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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:conduritol epoxide
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Accession:CHEBI:67235 term browser browse the term
Definition:An epoxide resulting from the epoxidation of the double bond of a conduritol.
Synonyms:exact_synonym: 7-oxabicyclo[4.1.0]heptane-2,3,4,5-tetrol
 related_synonym: Formula=C6H10O5;   InChI=1S/C6H10O5/c7-1-2(8)4(10)6-5(11-6)3(1)9/h1-10H;   InChIKey=ZHMWOVGZCINIHW-UHFFFAOYSA-N;   SMILES=OC1C(O)C(O)C2OC2C1O


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conduritol B epoxide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gba1 glucosylceramidase beta 1 multiple interactions
decreases activity		 ISO
EXP		 [conduritol epoxide binds to and results in decreased activity of GBA1 protein] which results in increased expression of SNCA protein
conduritol epoxide analog results in decreased activity of GBA1 protein
[conduritol epoxide binds to and results in decreased activity of GBA1 protein] which affects the localization of SNCA protein; [conduritol epoxide binds to and results in decreased activity of GBA1 protein] which results in increased expression of SNCA protein		 CTD PMID:9101438 PMID:19576930 NCBI chr 2:174,609,437...174,615,457
Ensembl chr 2:174,609,403...174,618,263 		JBrowse link
G Snca synuclein alpha multiple interactions ISO [conduritol epoxide binds to and results in decreased activity of GBA1 protein] which affects the localization of SNCA protein; [conduritol epoxide binds to and results in decreased activity of GBA1 protein] which results in increased expression of SNCA protein CTD PMID:19576930 NCBI chr 4:89,696,420...89,797,240
Ensembl chr 4:89,696,420...89,796,262 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19880
    chemical entity 19878
      molecular entity 19878
        main group molecular entity 19817
          gas molecular entity 18472
            oxirane 11285
              epoxide 11284
                conduritol epoxide 2
                  1-D-1,2-anhydro-myo-inositol + 2
                  1-L-1,2-anhydro-myo-inositol + 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19880
    subatomic particle 19878
      composite particle 19878
        hadron 19878
          baryon 19878
            nucleon 19878
              atomic nucleus 19878
                atom 19878
                  main group element atom 19817
                    main group molecular entity 19817
                      s-block molecular entity 19653
                        hydrogen molecular entity 19634
                          hydrides 19144
                            organic hydride 18691
                              organic fundamental parent 18691
                                hydrocarbon 18442
                                  olefin 8922
                                    cyclic olefin 422
                                      monocyclic olefin 420
                                        cycloalkene 407
                                          cyclohexene 3
                                            conduritol 2
                                              conduritol epoxide 2
                                                1-D-1,2-anhydro-myo-inositol + 2
                                                1-L-1,2-anhydro-myo-inositol + 2
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