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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:ryanodine receptor agonist
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Accession:CHEBI:67114 term browser browse the term
Definition:A ryanodine receptor modulator which activates the receptor. Ryanodine receptors (RyRs) act as selective ion channels, modulating the release of calcium. Activating the receptors causes the release of calcium, so depleting internal calcium and ultimately preventing further muscle contraction.
Synonyms:related_synonym: RyR activator;   RyR activators;   RyR agonist;   RyR agonists;   RyRs activator;   RyRs agonist;   ryanodine receptor activator;   ryanodine receptor activators
 xref: PMID:30679133;   PMID:30684528;   PMID:31840405;   PMID:8597061;   Wikipedia:Ryanodine_receptor


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      CHEBI ontology 19867
        role 19837
          biological role 19835
            biophysical role 14052
              membrane transport modulator 13888
                calcium channel modulator 9707
                  ryanodine receptor modulator 3803
                    ryanodine receptor agonist 3755
                      4-chloro-m-cresol 5
                      caffeine + 3731
                      chlorantraniliprole 0
                      cyantraniliprole 0
                      cyclaniliprole 0
                      cyclic ADP-beta-D-ribose + 3
                      suramin 35
                      suramin sodium 0
                      tetraniliprole 0
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