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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:panaxydol
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Accession:CHEBI:66723 term browser browse the term
Definition:An acetylenic compound that has formula C17H24O2.
Synonyms:exact_synonym: (3R)-8-[(2R,3S)-3-heptyloxiran-2-yl]oct-1-ene-4,6-diyn-3-ol
 related_synonym: Formula=C17H24O2;   InChI=1S/C17H24O2/c1-3-5-6-7-10-13-16-17(19-16)14-11-8-9-12-15(18)4-2/h4,15-18H,2-3,5-7,10,13-14H2,1H3/t15-,16+,17-/m1/s1;   InChIKey=GVLDSGIQZAFIAN-IXDOHACOSA-N;   SMILES=CCCCCCC[C@@H]1O[C@@H]1CC#CC#C[C@H](O)C=C
 xref: CAS:72800-72-7;   KNApSAcK:C00030922
 xref_mesh: MESH:C055778
 xref: PMID:2092947;   Reaxys:7926422



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panaxydol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Afp alpha-fetoprotein decreases secretion ISO panaxydol results in decreased secretion of AFP protein CTD PMID:19450571 NCBI chr14:17,857,584...17,875,645
Ensembl chr14:17,857,584...17,875,649
JBrowse link
G Alb albumin increases secretion ISO panaxydol results in increased secretion of ALB protein CTD PMID:19450571 NCBI chr14:17,891,564...17,907,043
Ensembl chr14:17,891,582...17,911,865
JBrowse link
G Bdnf brain-derived neurotrophic factor multiple interactions EXP panaxydol inhibits the reaction [Oxygen deficiency results in decreased expression of BDNF mRNA]; panaxydol inhibits the reaction [Oxygen deficiency results in decreased secretion of BDNF protein]; panaxydol results in increased expression of and results in increased secretion of BDNF protein CTD PMID:18541227 PMID:18805406 NCBI chr 3:116,619,633...116,670,212
Ensembl chr 3:116,619,633...116,670,657
JBrowse link
G Casp3 caspase 3 multiple interactions EXP panaxydol inhibits the reaction [Oxygen deficiency results in increased activity of CASP3 protein] CTD PMID:18541227 NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression ISO panaxydol results in increased expression of CDKN1A mRNA; panaxydol results in increased expression of CDKN1A protein CTD PMID:19450571 NCBI chr20:7,150,820...7,161,373
Ensembl chr20:7,153,958...7,164,969
JBrowse link
G Id1 inhibitor of DNA binding 1 decreases expression ISO panaxydol results in decreased expression of ID1 mRNA CTD PMID:19450571 NCBI chr 3:161,671,525...161,672,691
Ensembl chr 3:161,671,538...161,672,685
JBrowse link
G Id2 inhibitor of DNA binding 2 decreases expression ISO panaxydol results in decreased expression of ID2 mRNA CTD PMID:19450571 NCBI chr 6:47,469,162...47,470,995
Ensembl chr 6:47,457,554...47,472,961
JBrowse link
G Ngf nerve growth factor multiple interactions
increases secretion
EXP panaxydol promotes the reaction [Oxygen deficiency results in increased expression of NGF mRNA]; panaxydol results in increased expression of and results in increased secretion of NGF protein
panaxydol results in increased secretion of NGF protein
CTD PMID:18541227 PMID:18805406 NCBI chr 2:192,589,580...192,642,971
Ensembl chr 2:192,589,582...192,643,834
JBrowse link
G Rb1 RB transcriptional corepressor 1 increases expression ISO panaxydol results in increased expression of RB1 protein; panaxydol results in increased expression of RB1 protein modified form CTD PMID:19450571 NCBI chr15:54,780,858...54,911,989
Ensembl chr15:54,780,858...54,911,857
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20862
    chemical entity 20860
      molecular entity 20859
        main group molecular entity 20781
          gas molecular entity 18922
            oxirane 11487
              epoxide 11486
                panaxydol 9
Path 2
Term Annotations click to browse term
  CHEBI ontology 20862
    subatomic particle 20860
      composite particle 20860
        hadron 20860
          baryon 20860
            nucleon 20860
              atomic nucleus 20860
                atom 20860
                  main group element atom 20781
                    p-block element atom 20781
                      carbon group element atom 20715
                        carbon atom 20710
                          organic molecular entity 20710
                            organic molecule 20654
                              organic cyclic compound 20404
                                organic heterocyclic compound 19388
                                  organic heteromonocyclic compound 18212
                                    saturated organic heteromonocyclic parent 11505
                                      oxirane 11487
                                        epoxide 11486
                                          panaxydol 9
paths to the root