CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: malathion
Accession: CHEBI:6651
browse the term
Definition: A racemate comprising equimolar amounts of (R) and (S)-malathion. It is a broad spectrum organophosphate proinsecticide used to control a wide range of pests including Coleoptera, Diptera, fruit flies, mosquitos and spider mites.
Synonyms: exact_synonym: rac-diethyl 2-[(dimethoxyphosphorothioyl)thio]succinate
related_synonym: Karbofos; Maldison; O,O-dimethyl S-(1,2-bis(ethoxycarbonyl)ethyl); O,O-dimethyl S-(1,2-dicarbethoxyethyl) dithiophosphate; O,O-dimethyl S-(1,2-dicarbethoxyethyl)phosphorodithioate; O,O-dimethyl S-1,2-di(ethoxycarbamyl)ethyl; O,O-dimethyldithiophosphate diethylmercaptosuccinate; [(dimethoxyphosphinothioyl)thio]butanedioic acid diethyl ester; carbophos; diethyl ((dimethoxyphosphinothioyl)thio)butanedioate; diethyl (dimethoxyphosphinothioylthio)succinate; diethyl 2-[(dimethoxyphosphorothioyl)sulfanyl]butanedioate; mercaptothion
xref: CAS:121-75-5; DrugBank:DB00772; Drug_Central:1626; KEGG:C07497; KEGG:D00534
xref_mesh: MESH:D008294
xref: PMID:16083681; PMID:19399610; PMID:28950791; PMID:29235025; PMID:29792547; PMID:29852369; Reaxys:1804525; Wikipedia:Malathion
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Acbd5
acyl-CoA binding domain containing 5
increases expression
ISO
Malathion results in increased expression of ACBD5 mRNA
CTD
PMID:37047231
NCBI chr17:85,206,178...85,248,909
Ensembl chr17:85,206,303...85,248,215
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Ache
acetylcholinesterase
multiple interactions decreases activity
ISO EXP
[Malathion co-treated with Dichlorvos] results in decreased activity of ACHE protein; Obidoxime Chloride inhibits the reaction [Malathion results in decreased activity of ACHE protein]; Oximes analog inhibits the reaction [Malathion results in decreased activity of ACHE protein]; pralidoxime inhibits the reaction [Malathion results in decreased activity of ACHE protein] [Endosulfan co-treated with Malathion] results in decreased activity of ACHE protein; [Malathion co-treated with Permethrin] results in decreased activity of ACHE protein; [Malathion co-treated with Permethrin] results in increased activity of ACHE protein; Taurine inhibits the reaction [Malathion results in decreased activity of ACHE protein]; zinc chloride inhibits the reaction [Malathion results in decreased activity of ACHE protein]
CTD
PMID:2380476 PMID:4859365 PMID:14713564 PMID:18617161 PMID:19429256 PMID:19784758 PMID:21628957 PMID:21723318 PMID:21983245 PMID:23774768 PMID:28987951 PMID:30625376 More...
NCBI chr12:19,406,133...19,413,713
Ensembl chr12:19,407,360...19,413,651
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Acot6
acyl-CoA thioesterase 6
decreases expression
ISO
Malathion results in decreased expression of ACOT6 mRNA
CTD
PMID:37047231
NCBI chr 6:103,732,372...103,741,446
Ensembl chr 6:103,732,372...103,741,446
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Acsm1
acyl-CoA synthetase medium-chain family member 1
decreases expression
ISO
Malathion results in decreased expression of ACSM1 mRNA
CTD
PMID:17311802
NCBI chr 1:173,985,715...174,020,565
Ensembl chr 1:173,984,672...174,025,495
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Adam11
ADAM metallopeptidase domain 11
increases methylation
ISO
Malathion results in increased methylation of ADAM11 promoter
CTD
PMID:37047231
NCBI chr10:87,724,115...87,742,773
Ensembl chr10:87,724,234...87,741,562
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Adam32
ADAM metallopeptidase domain 32
decreases expression
ISO
Malathion results in decreased expression of ADAM32 mRNA
CTD
PMID:37047231
NCBI chr16:67,102,384...67,212,163
Ensembl chr16:67,102,320...67,212,161
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Adamts12
ADAM metallopeptidase with thrombospondin type 1 motif, 12
decreases expression
ISO
Malathion results in decreased expression of ADAMTS12 mRNA
CTD
PMID:37047231
NCBI chr 2:60,032,873...60,327,629
Ensembl chr 2:60,032,873...60,327,629
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Adamts20
ADAM metallopeptidase with thrombospondin type 1 motif, 20
decreases expression
ISO
Malathion results in decreased expression of ADAMTS20 mRNA
CTD
PMID:37047231
NCBI chr 7:125,396,227...125,528,020
Ensembl chr 7:125,397,734...125,527,777
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Adamts6
ADAM metallopeptidase with thrombospondin type 1 motif, 6
increases expression
ISO
Malathion results in increased expression of ADAMTS6 mRNA
CTD
PMID:37047231
NCBI chr 2:35,421,483...35,633,305
Ensembl chr 2:35,421,510...35,633,298
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Add3
adducin 3
increases expression
EXP
Malathion results in increased expression of ADD3 mRNA
CTD
PMID:19784758
NCBI chr 1:252,147,341...252,255,126
Ensembl chr 1:252,147,386...252,255,124
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Adm
adrenomedullin
increases expression
ISO
Malathion results in increased expression of ADM mRNA
CTD
PMID:37047231
NCBI chr 1:164,745,484...164,747,655
Ensembl chr 1:164,745,466...164,747,654
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Adra2a
adrenoceptor alpha 2A
increases expression
ISO
Malathion results in increased expression of ADRA2A mRNA
CTD
PMID:37047231
NCBI chr 1:253,061,480...253,064,280
Ensembl chr 1:253,060,218...253,064,365
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Aff1
ALF transcription elongation factor 1
increases expression
ISO
Malathion results in increased expression of AFF1 mRNA mutant form
CTD
PMID:28624474
NCBI chr14:5,861,188...6,024,196
Ensembl chr14:5,863,961...6,024,729
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Ahr
aryl hydrocarbon receptor
multiple interactions
ISO
[prothioconazole co-treated with terbutylazine co-treated with bitertanol co-treated with cypermethrin co-treated with Malathion] results in increased activity of AHR protein
CTD
PMID:25684042
NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
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Akr1c1
aldo-keto reductase family 1, member C1
increases expression
ISO
Malathion results in increased expression of AKR1C1 mRNA
CTD
PMID:16079077 PMID:18214805
NCBI chr17:65,810,474...65,837,385
Ensembl chr17:65,810,475...65,837,326
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Akr1c2
aldo-keto reductase family 1, member C2
increases expression
ISO
Malathion results in increased expression of AKR1C2 mRNA
CTD
PMID:16079077
NCBI chr17:65,759,778...65,808,013
Ensembl chr17:65,759,788...65,775,764
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Akr1e2
aldo-keto reductase family 1, member E2
decreases expression
ISO
Malathion results in decreased expression of AKR1E2 mRNA
CTD
PMID:37047231
NCBI chr17:65,735,909...65,750,441
Ensembl chr17:65,735,943...65,750,441
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Alkal2
ALK and LTK ligand 2
increases expression
ISO
Malathion results in increased expression of ALKAL2 mRNA
CTD
PMID:37047231
NCBI chr 6:47,495,645...47,505,235
Ensembl chr 6:47,495,782...47,505,234
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Alpl
alkaline phosphatase, biomineralization associated
increases activity multiple interactions
EXP
Malathion results in increased activity of ALPL protein thymoquinone inhibits the reaction [Malathion results in increased activity of ALPL protein]
CTD
PMID:33510276
NCBI chr 5:149,951,397...150,006,424
Ensembl chr 5:149,951,409...150,006,446
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Amot
angiomotin
decreases expression
ISO
Malathion results in decreased expression of AMOT mRNA
CTD
PMID:37047231
NCBI chr X:108,982,399...109,041,265
Ensembl chr X:108,984,022...109,041,272
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Angptl2
angiopoietin-like 2
decreases expression
ISO
Malathion results in decreased expression of ANGPTL2 mRNA
CTD
PMID:37047231
NCBI chr 3:16,517,185...16,547,024
Ensembl chr 3:16,517,420...16,548,178
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Angptl4
angiopoietin-like 4
decreases methylation increases expression
ISO
Malathion results in decreased methylation of ANGPTL4 promoter Malathion results in increased expression of ANGPTL4 mRNA
CTD
PMID:37047231
NCBI chr 7:14,550,288...14,557,797
Ensembl chr 7:14,550,311...14,556,519
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Ank1
ankyrin 1
decreases expression
ISO
Malathion results in decreased expression of ANK1 mRNA
CTD
PMID:37047231
NCBI chr16:68,876,294...69,054,963
Ensembl chr16:68,877,504...69,054,759
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Ankrd55
ankyrin repeat domain 55
increases expression
ISO
Malathion results in increased expression of ANKRD55 mRNA
CTD
PMID:37047231
NCBI chr 2:43,883,877...43,983,820
Ensembl chr 2:43,883,857...43,983,680
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Aplf
aprataxin and PNKP like factor
decreases expression
ISO
Malathion results in decreased expression of APLF mRNA
CTD
PMID:37047231
NCBI chr 4:120,070,471...120,122,656
Ensembl chr 4:120,070,471...120,122,633
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Aqp12a
aquaporin 12A
decreases expression
ISO
Malathion results in decreased expression of AQP12A mRNA
CTD
PMID:37047231
NCBI chr 9:93,554,527...93,560,011
Ensembl chr 9:93,554,527...93,560,011
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Aqp9
aquaporin 9
increases expression
ISO
Malathion results in increased expression of AQP9 mRNA
CTD
PMID:37047231
NCBI chr 8:71,797,231...71,837,485
Ensembl chr 8:71,797,234...71,837,395
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Ar
androgen receptor
multiple interactions decreases expression
ISO EXP
[terbutylazine co-treated with bitertanol co-treated with propiconazole co-treated with cypermethrin co-treated with Malathion] inhibits the reaction [Dihydrotestosterone binds to and results in increased activity of AR protein]; [terbutylazine co-treated with bitertanol co-treated with propiconazole co-treated with cypermethrin co-treated with Malathion] results in decreased activity of AR protein Malathion results in decreased expression of AR mRNA
CTD
PMID:23871939 PMID:36336997
NCBI chr X:63,104,771...63,273,934
Ensembl chr X:63,104,771...63,273,925
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Armc3
armadillo repeat containing 3
decreases expression
ISO
Malathion results in decreased expression of ARMC3 mRNA
CTD
PMID:37047231
NCBI chr17:81,814,087...81,917,534
Ensembl chr17:81,832,518...81,917,531
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Arnt2
aryl hydrocarbon receptor nuclear translocator 2
decreases expression
ISO
Malathion results in decreased expression of ARNT2 mRNA
CTD
PMID:37047231
NCBI chr 1:138,236,235...138,392,868
Ensembl chr 1:138,189,940...138,393,153
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Asic5
acid sensing ion channel subunit family member 5
increases expression
ISO
Malathion results in increased expression of ASIC5 mRNA
CTD
PMID:37047231
NCBI chr 2:167,307,984...167,336,812
Ensembl chr 2:167,307,984...167,336,812
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Atp2b3
ATPase plasma membrane Ca2+ transporting 3
decreases expression
ISO
Malathion results in decreased expression of ATP2B3 mRNA
CTD
PMID:37047231
NCBI chr X:151,216,483...151,289,069
Ensembl chr X:151,216,507...151,286,775
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B4galt1
beta-1,4-galactosyltransferase 1
decreases expression
ISO
Malathion results in decreased expression of B4GALT1 mRNA
CTD
PMID:32069766
NCBI chr 5:55,935,614...55,982,461
Ensembl chr 5:55,935,615...55,982,461
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B9d1
B9 domain containing 1
decreases expression
ISO
Malathion results in decreased expression of B9D1 mRNA
CTD
PMID:37047231
NCBI chr10:46,186,222...46,196,309
Ensembl chr10:46,186,691...46,196,008
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Bax
BCL2 associated X, apoptosis regulator
decreases expression multiple interactions increases expression
EXP ISO
Malathion results in decreased expression of BAX mRNA Acetylcysteine inhibits the reaction [Malathion results in increased expression of BAX protein] Plant Extracts inhibits the reaction [Malathion results in increased expression of BAX protein]; Polyphenols inhibits the reaction [Malathion results in increased expression of BAX protein] crocin inhibits the reaction [Malathion results in increased expression of BAX protein]
CTD
PMID:23774768 PMID:30769050 PMID:32120800 PMID:35274200
NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
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Bche
butyrylcholinesterase
multiple interactions decreases activity increases activity
ISO EXP
Obidoxime Chloride inhibits the reaction [Malathion results in decreased activity of BCHE protein] Malathion results in increased activity of BCHE protein
CTD
PMID:17364237 PMID:18617161 PMID:21983245 PMID:25180440
NCBI chr 2:158,308,674...158,401,148
Ensembl chr 2:158,307,584...158,401,148
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Bcl2
BCL2, apoptosis regulator
decreases expression multiple interactions increases expression
EXP ISO
Malathion results in decreased expression of BCL2 mRNA Malathion results in decreased expression of BCL2 protein Acetylcysteine inhibits the reaction [Malathion results in decreased expression of BCL2 protein] Malathion results in increased expression of BCL2 protein Malathion results in increased expression of BCL2 mRNA
CTD
PMID:23774768 PMID:30673264 PMID:30769050 PMID:32120800
NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743 Ensembl chr13:22,684,989...22,853,743
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Bdnf
brain-derived neurotrophic factor
multiple interactions
ISO
[Pesticides results in increased abundance of Malathion metabolite] which results in decreased secretion of BDNF protein; [Pesticides results in increased abundance of Malathion metabolite] which results in increased methylation of BDNF gene
CTD
PMID:35292247
NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615
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Birc5
baculoviral IAP repeat-containing 5
increases expression multiple interactions
EXP
Malathion results in increased expression of BIRC5 protein Rosmarinic Acid inhibits the reaction [Malathion results in increased expression of BIRC5 protein]; thymoquinone inhibits the reaction [Malathion results in increased expression of BIRC5 protein]
CTD
PMID:33510276 PMID:34262720
NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380
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Bmi1
BMI1 proto-oncogene, polycomb ring finger
increases expression
ISO
Malathion results in increased expression of BMI1 mRNA
CTD
PMID:32069766
NCBI chr17:81,332,175...81,341,625
Ensembl chr17:81,332,214...81,388,690
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Brd7
bromodomain containing 7
increases expression
ISO
Malathion results in increased expression of BRD7 mRNA
CTD
PMID:18214912
NCBI chr19:18,708,792...18,737,497
Ensembl chr19:18,709,022...18,737,494
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Bsnd
barttin CLCNK type accessory subunit beta
increases expression
ISO
Malathion results in increased expression of BSND mRNA
CTD
PMID:37047231
NCBI chr 5:121,251,774...121,260,571
Ensembl chr 5:121,251,774...121,260,571
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Btg1
BTG anti-proliferation factor 1
decreases expression
ISO
Malathion results in decreased expression of BTG1 mRNA
CTD
PMID:32069766
NCBI chr 7:31,341,391...31,343,649
Ensembl chr 7:31,341,027...31,343,649
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Bub1
BUB1 mitotic checkpoint serine/threonine kinase
decreases expression
ISO
Malathion results in decreased expression of BUB1 mRNA
CTD
PMID:16079077
NCBI chr 3:115,020,254...115,051,650
Ensembl chr 3:115,020,254...115,051,650
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C16h10orf53
similar to human chromosome 10 open reading frame 53
decreases expression
ISO
Malathion results in decreased expression of C10ORF53 mRNA
CTD
PMID:37047231
NCBI chr16:7,634,207...7,644,876
Ensembl chr16:7,634,207...7,644,876
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C1ql2
complement C1q like 2
decreases expression
ISO
Malathion results in decreased expression of C1QL2 mRNA
CTD
PMID:37047231
NCBI chr13:31,471,150...31,472,685
Ensembl chr13:31,471,150...31,472,689
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C2h3orf80
similar to human chromosome 3 open reading frame 80
decreases expression
ISO
Malathion results in decreased expression of C3ORF80 mRNA
CTD
PMID:37047231
NCBI chr 2:153,125,312...153,128,124
Ensembl chr 2:153,125,676...153,126,419
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C3h11orf96
similar to human chromosome 11 open reading frame 96
increases expression
ISO
Malathion results in increased expression of C11ORF96 mRNA
CTD
PMID:37047231
NCBI chr 3:79,920,125...79,921,368
Ensembl chr 3:79,920,129...79,921,523
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C3h15orf48
similar to human chromosome 15 open reading frame 48
increases expression
ISO
Malathion results in increased expression of C15ORF48 mRNA
CTD
PMID:37047231
NCBI chr 3:109,719,952...109,723,505
Ensembl chr 3:109,719,897...109,724,006 Ensembl chr 3:109,719,897...109,724,006
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C5h8orf34
similar to human chromosome 8 open reading frame 34
decreases expression
ISO
Malathion results in decreased expression of C8ORF34 mRNA
CTD
PMID:37047231
NCBI chr 5:7,237,968...7,777,119
Ensembl chr 5:7,238,853...7,776,769
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C7h12orf54
similar to human chromosome 12 open reading frame 54
decreases expression
ISO
Malathion results in decreased expression of C12ORF54 mRNA
CTD
PMID:37047231
NCBI chr 7:129,529,811...129,548,676
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Cabp7
calcium binding protein 7
decreases expression
ISO
Malathion results in decreased expression of CABP7 mRNA
CTD
PMID:37047231
NCBI chr14:79,598,822...79,609,172
Ensembl chr14:79,598,827...79,609,240
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Cacna1c
calcium voltage-gated channel subunit alpha1 C
increases expression
ISO
Malathion results in increased expression of CACNA1C mRNA
CTD
PMID:37047231
NCBI chr 4:151,764,138...152,379,454
Ensembl chr 4:151,764,138...152,379,648
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Camk2a
calcium/calmodulin-dependent protein kinase II alpha
multiple interactions
EXP
Malathion promotes the reaction [NGF protein results in increased expression of CAMK2A mRNA]
CTD
PMID:28385489
NCBI chr18:54,378,642...54,441,120
Ensembl chr18:54,378,784...54,438,994
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Camk2b
calcium/calmodulin-dependent protein kinase II beta
multiple interactions
EXP
Malathion promotes the reaction [NGF protein results in increased expression of CAMK2B mRNA]
CTD
PMID:28385489
NCBI chr14:80,845,206...80,934,172
Ensembl chr14:80,845,238...80,933,994
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Capn8
calpain 8
decreases expression
ISO
Malathion results in decreased expression of CAPN8 mRNA
CTD
PMID:37047231
NCBI chr13:94,252,218...94,316,146
Ensembl chr13:94,253,054...94,316,146
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Cartpt
CART prepropeptide
increases expression
ISO
Malathion results in increased expression of CARTPT mRNA
CTD
PMID:37047231
NCBI chr 2:31,255,098...31,257,452
Ensembl chr 2:31,255,098...31,290,713
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Casp3
caspase 3
increases activity multiple interactions increases expression increases cleavage
ISO EXP
Malathion results in increased activity of CASP3 protein [Vitamin E co-treated with Selenium] inhibits the reaction [Malathion results in increased expression of CASP3 mRNA]; crocin inhibits the reaction [Malathion results in increased cleavage of CASP3 protein]; Levodopa inhibits the reaction [Malathion results in increased cleavage of CASP3 protein] Acetylcysteine inhibits the reaction [Malathion results in increased cleavage of CASP3 protein] Malathion results in increased activity of and results in increased cleavage of CASP3 protein; Metoclopramide inhibits the reaction [Malathion results in increased activity of and results in increased cleavage of CASP3 protein]
CTD
PMID:12505448 PMID:19815060 PMID:21628957 PMID:27941166 PMID:29027213 PMID:30769050 PMID:35274200 More...
NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
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Casp4
caspase 4
decreases expression
ISO
Malathion results in decreased expression of CASP4 mRNA
CTD
PMID:32069766
NCBI chr 8:2,599,017...2,635,097
Ensembl chr 8:2,598,876...2,635,092
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Casp8
caspase 8
increases activity
ISO
Malathion results in increased activity of CASP8 protein
CTD
PMID:12505448
NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
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Casp9
caspase 9
increases activity increases expression multiple interactions increases cleavage
ISO EXP
Malathion results in increased activity of CASP9 protein Malathion results in increased expression of CASP9 mRNA [Vitamin E co-treated with Selenium] inhibits the reaction [Malathion results in increased expression of CASP9 mRNA]; crocin inhibits the reaction [Malathion results in increased cleavage of CASP9 protein]; Levodopa inhibits the reaction [Malathion results in increased cleavage of CASP9 protein] Acetylcysteine inhibits the reaction [Malathion results in increased cleavage of CASP9 protein]
CTD
PMID:12505448 PMID:21628957 PMID:27941166 PMID:30769050 PMID:35274200
NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
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Cat
catalase
multiple interactions decreases activity increases activity decreases expression
EXP ISO
[Dimethoate co-treated with Malathion] results in increased activity of CAT protein; [Selenium co-treated with Vitamin E] inhibits the reaction [Malathion results in decreased activity of CAT protein]; Acetylcysteine inhibits the reaction [Malathion results in increased activity of CAT protein]; alpha-Tocopherol inhibits the reaction [Malathion results in increased activity of CAT protein]; Pentoxifylline inhibits the reaction [Malathion results in increased activity of CAT protein]; Taurine inhibits the reaction [Malathion results in decreased activity of CAT protein]; Vitamin E inhibits the reaction [Malathion results in increased activity of CAT protein]; zinc chloride inhibits the reaction [Malathion results in decreased activity of CAT protein] [Malathion co-treated with 1,4-bis(4-hydroxyiminomethylpyridinium)butane dibromide] results in increased activity of CAT protein; [Malathion co-treated with pralidoxime] results in increased activity of CAT protein; lavender oil inhibits the reaction [Malathion results in decreased expression of CAT protein]; Plant Extracts inhibits the reaction [Malathion results in decreased activity of CAT protein]; Polyphenols inhibits the reaction [Malathion results in decreased activity of CAT protein] [Ascorbic Acid co-treated with Vitamin E] inhibits the reaction [Malathion results in increased activity of CAT protein]; Acetylcysteine inhibits the reaction [Malathion results in decreased activity of CAT protein]; Ascorbic Acid inhibits the reaction [Malathion results in increased activity of CAT protein]; Vitamin E inhibits the reaction [Malathion results in increased activity of CAT protein]
CTD
PMID:11834209 PMID:18655177 PMID:19429256 PMID:20194575 PMID:21628957 PMID:21723318 PMID:24810974 PMID:25180440 PMID:28987951 PMID:30409133 PMID:30673264 PMID:30769050 PMID:32120800 PMID:36336997 More...
NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
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Cbfb
core-binding factor subunit beta
increases expression
ISO
Malathion results in increased expression of CBFB mRNA
CTD
PMID:32069766
NCBI chr19:33,049,162...33,092,752
Ensembl chr19:33,049,172...33,092,751
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Ccdc126
coiled-coil domain containing 126
increases expression
ISO
Malathion results in increased expression of CCDC126 mRNA
CTD
PMID:37047231
NCBI chr 4:78,297,625...78,318,655
Ensembl chr 4:78,297,551...78,318,655
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Cck
cholecystokinin
increases expression
EXP
Malathion results in increased expression of CCK mRNA
CTD
PMID:19784758
NCBI chr 8:121,153,499...121,160,194
Ensembl chr 8:121,153,500...121,160,084
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Ccl1
C-C motif chemokine ligand 1
increases expression
ISO
Malathion results in increased expression of CCL1 mRNA
CTD
PMID:37047231
NCBI chr10:67,128,331...67,131,109
Ensembl chr10:67,128,331...67,131,159
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Ccl19
C-C motif chemokine ligand 19
increases expression
ISO
Malathion results in increased expression of CCL19 mRNA
CTD
PMID:37047231
NCBI chr 5:56,963,364...56,965,308
Ensembl chr 5:56,963,364...56,965,308
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Ccl20
C-C motif chemokine ligand 20
increases expression
ISO
Malathion results in increased expression of CCL20 mRNA
CTD
PMID:37047231
NCBI chr 9:84,389,031...84,391,629
Ensembl chr 9:84,388,904...84,391,629
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Ccl3
C-C motif chemokine ligand 3
increases expression
ISO
Malathion results in increased expression of CCL3 mRNA
CTD
PMID:37047231
NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938
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Ccl7
C-C motif chemokine ligand 7
increases expression
ISO
Malathion results in increased expression of CCL7 mRNA
CTD
PMID:37047231
NCBI chr10:67,016,446...67,018,296
Ensembl chr10:67,016,446...67,018,303
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Ccm2l
CCM2 like scaffold protein
increases expression
ISO
Malathion results in increased expression of CCM2L mRNA
CTD
PMID:37047231
NCBI chr 3:141,533,470...141,549,136
Ensembl chr 3:141,533,511...141,549,140
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Ccna2
cyclin A2
decreases expression
ISO
Malathion results in decreased expression of CCNA2 protein
CTD
PMID:30769050
NCBI chr 2:119,427,239...119,433,645
Ensembl chr 2:119,426,089...119,433,577
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Ccnb1
cyclin B1
decreases expression
ISO
Malathion results in decreased expression of CCNB1 protein
CTD
PMID:30769050
NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172
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Ccne1
cyclin E1
decreases expression
ISO
Malathion results in decreased expression of CCNE1 protein
CTD
PMID:30769050
NCBI chr 1:90,781,947...90,791,188
Ensembl chr 1:90,781,949...90,791,101
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Ccser1
coiled-coil serine-rich protein 1
increases expression
ISO
Malathion results in increased expression of CCSER1 mRNA
CTD
PMID:37047231
NCBI chr 4:90,153,873...91,391,441
Ensembl chr 4:90,292,780...91,388,786
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Cd14
CD14 molecule
decreases expression
ISO
Malathion results in decreased expression of CD14 mRNA
CTD
PMID:32069766
NCBI chr18:28,335,522...28,337,383
Ensembl chr18:28,335,340...28,337,261
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Cd274
CD274 molecule
increases expression
ISO
Malathion results in increased expression of CD274 mRNA
CTD
PMID:37047231
NCBI chr 1:227,116,674...227,137,379
Ensembl chr 1:227,116,649...227,134,450
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Cd36
CD36 molecule
increases expression
ISO
Malathion results in increased expression of CD36 mRNA
CTD
PMID:32069766
NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903
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Cd5
Cd5 molecule
decreases expression
ISO
Malathion results in decreased expression of CD5 mRNA
CTD
PMID:32069766
NCBI chr 1:207,365,337...207,386,313
Ensembl chr 1:207,365,337...207,386,313
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Cd69
Cd69 molecule
increases expression
ISO
Malathion results in increased expression of CD69 mRNA
CTD
PMID:37047231
NCBI chr 4:162,725,446...162,733,364
Ensembl chr 4:162,725,446...162,733,542
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Cdc20
cell division cycle 20
decreases expression
ISO
Malathion results in decreased expression of CDC20 mRNA
CTD
PMID:18214805
NCBI chr 5:131,966,203...131,970,406
Ensembl chr 5:131,966,215...131,970,512
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Cdk15
cyclin-dependent kinase 15
increases expression
ISO
Malathion results in increased expression of CDK15 mRNA
CTD
PMID:37047231
NCBI chr 9:60,710,787...60,803,638
Ensembl chr 9:60,711,715...60,802,777
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Cdk2
cyclin dependent kinase 2
decreases expression increases expression
ISO
Malathion results in decreased expression of CDK2 protein Malathion results in increased expression of CDK2 mRNA
CTD
PMID:30769050 PMID:32069766
NCBI chr 7:1,129,878...1,137,431
Ensembl chr 7:1,129,811...1,137,403
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Cebpg
CCAAT/enhancer binding protein gamma
increases expression
ISO
Malathion results in increased expression of CEBPG mRNA
CTD
PMID:32069766
NCBI chr 1:87,683,060...87,692,772
Ensembl chr 1:87,684,019...87,694,569
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Cenpf
centromere protein F
decreases expression
ISO
Malathion results in decreased expression of CENPF mRNA
CTD
PMID:16079077
NCBI chr13:101,184,127...101,229,714
Ensembl chr13:101,184,127...101,229,669
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Ces1d
carboxylesterase 1D
increases expression
ISO
Malathion results in increased expression of CES1 mRNA
CTD
PMID:17311802
NCBI chr19:13,873,490...13,912,035
Ensembl chr19:13,796,623...13,912,035
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Cfap157
cilia and flagella associated protein 157
decreases expression
ISO
Malathion results in decreased expression of CFAP157 mRNA
CTD
PMID:37047231
NCBI chr 3:16,066,521...16,073,504
Ensembl chr 3:16,066,521...16,073,495
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Cfap91
cilia and flagella associated protein 91
decreases expression
ISO
Malathion results in decreased expression of CFAP91 mRNA
CTD
PMID:37047231
NCBI chr11:62,413,613...62,457,281
Ensembl chr11:62,413,602...62,457,293
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Cfb
complement factor B
increases expression
ISO
Malathion results in increased expression of CFB mRNA
CTD
PMID:37047231
NCBI chr20:3,970,643...3,976,510
Ensembl chr20:3,951,474...3,976,505
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Ch25h
cholesterol 25-hydroxylase
increases expression
ISO
Malathion results in increased expression of CH25H mRNA
CTD
PMID:37047231
NCBI chr 1:232,014,877...232,016,195
Ensembl chr 1:232,014,880...232,016,195
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Cldn12
claudin 12
increases expression
ISO
Malathion results in increased expression of CLDN12 mRNA
CTD
PMID:37047231
NCBI chr 4:28,522,659...28,533,647
Ensembl chr 4:28,522,678...28,533,801
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Cldn22
claudin 22
decreases expression
ISO
Malathion results in decreased expression of CLDN22 mRNA
CTD
PMID:37047231
NCBI chr16:44,422,344...44,423,370
Ensembl chr16:44,422,345...44,423,354
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Cldn5
claudin 5
multiple interactions decreases expression
EXP
[Malathion co-treated with Lead] results in decreased expression of CLDN5 protein Malathion results in decreased expression of CLDN5 protein
CTD
PMID:20970449
NCBI chr11:82,212,822...82,214,248
Ensembl chr11:82,211,475...82,214,992
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Cma1
chymase 1
decreases expression
ISO
Malathion results in decreased expression of CMA1 mRNA
CTD
PMID:37047231
NCBI chr15:29,417,451...29,420,233
Ensembl chr15:29,417,451...29,420,233
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Cntn4
contactin 4
increases expression
ISO
Malathion results in increased expression of CNTN4 mRNA
CTD
PMID:37047231
NCBI chr 4:138,624,584...139,622,499
Ensembl chr 4:139,099,152...139,621,090
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Col1a2
collagen type I alpha 2 chain
increases expression
ISO
Malathion results in increased expression of COL1A2 mRNA
CTD
PMID:32069766
NCBI chr 4:32,563,938...32,598,868
Ensembl chr 4:32,563,381...32,598,867
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Cpne9
copine family member 9
decreases expression
ISO
Malathion results in decreased expression of CPNE9 mRNA
CTD
PMID:37047231
NCBI chr 4:146,429,961...146,454,335
Ensembl chr 4:146,430,792...146,454,333
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Cpz
carboxypeptidase Z
decreases expression
ISO
Malathion results in decreased expression of CPZ mRNA
CTD
PMID:37047231
NCBI chr14:75,223,692...75,246,946
Ensembl chr14:75,223,605...75,246,945
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Crh
corticotropin releasing hormone
multiple interactions decreases expression
EXP
caffeic acid inhibits the reaction [Malathion results in decreased expression of CRH mRNA]
CTD
PMID:20233601 PMID:25404496
NCBI chr 2:102,143,055...102,144,919
Ensembl chr 2:102,143,055...102,144,919
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Crisp3
cysteine-rich secretory protein 3
decreases expression
ISO
Malathion results in decreased expression of CRISP3 mRNA
CTD
PMID:37047231
NCBI chr 9:20,432,051...20,472,663
Ensembl chr 9:20,450,908...20,472,658
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Crispld2
cysteine-rich secretory protein LCCL domain containing 2
decreases expression
EXP
Malathion results in decreased expression of CRISPLD2 mRNA
CTD
PMID:19784758
NCBI chr19:48,053,153...48,111,485
Ensembl chr19:48,053,287...48,110,465
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Csf2
colony stimulating factor 2
increases expression
EXP ISO
Malathion results in increased expression of CSF2 protein Malathion results in increased expression of CSF2 mRNA
CTD
PMID:34778934 PMID:37047231
NCBI chr10:38,386,945...38,388,926
Ensembl chr10:38,386,945...38,389,199
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Csf3
colony stimulating factor 3
increases expression
ISO
Malathion results in increased expression of CSF3 mRNA
CTD
PMID:37047231
NCBI chr10:83,660,787...83,664,569
Ensembl chr10:83,661,207...83,663,603
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Ctsd
cathepsin D
increases expression
ISO
Malathion results in increased expression of CTSD protein
CTD
PMID:8812242
NCBI chr 1:197,527,467...197,539,343
Ensembl chr 1:197,527,467...197,539,488
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Cxcl11
C-X-C motif chemokine ligand 11
increases expression
ISO
Malathion results in increased expression of CXCL11 mRNA
CTD
PMID:37047231
NCBI chr14:15,689,432...15,692,207
Ensembl chr14:15,689,424...15,692,271
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Cybb
cytochrome b-245 beta chain
multiple interactions increases expression
ISO
Plant Extracts inhibits the reaction [Malathion results in increased expression of CYBB protein]; Polyphenols inhibits the reaction [Malathion results in increased expression of CYBB protein]
CTD
PMID:32120800
NCBI chr X:13,358,101...13,392,570
Ensembl chr X:13,359,430...13,392,586
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Cyp11a1
cytochrome P450, family 11, subfamily a, polypeptide 1
decreases expression multiple interactions
ISO
Malathion results in decreased expression of CYP11A1 mRNA lavender oil inhibits the reaction [Malathion results in decreased expression of CYP11A1 mRNA]
CTD
PMID:30409133
NCBI chr 8:58,422,807...58,434,342
Ensembl chr 8:58,404,669...58,434,338
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Cyp19a1
cytochrome P450, family 19, subfamily a, polypeptide 1
multiple interactions
EXP
[bitertanol co-treated with propiconazole co-treated with cypermethrin co-treated with Malathion co-treated with terbutylazine] results in increased expression of CYP19A1 mRNA
CTD
PMID:23954766
NCBI chr 8:54,552,978...54,580,375
Ensembl chr 8:54,553,165...54,580,758
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Cyp1a2
cytochrome P450, family 1, subfamily a, polypeptide 2
affects metabolic processing increases expression
ISO
CYP1A2 protein affects the metabolism of Malathion Malathion results in increased expression of CYP1A2 mRNA
CTD
PMID:15557345 PMID:22310298
NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
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Cyp27b1
cytochrome P450, family 27, subfamily b, polypeptide 1
increases expression
ISO
Malathion results in increased expression of CYP27B1 mRNA
CTD
PMID:37047231
NCBI chr 7:62,869,340...62,876,242
Ensembl chr 7:62,871,297...62,876,241
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Cyp2b3
cytochrome P450, family 2, subfamily b, polypeptide 3
affects metabolic processing decreases activity increases expression multiple interactions
ISO
CYP2B6 protein affects the metabolism of Malathion Malathion results in decreased activity of CYP2B6 protein Malathion results in increased expression of CYP2B6 mRNA Malathion promotes the reaction [isomalathion results in increased expression of CYP2B6 mRNA]
CTD
PMID:15557345 PMID:22310298 PMID:24333466
NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143
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Cyp2e1
cytochrome P450, family 2, subfamily e, polypeptide 1
multiple interactions decreases activity
ISO
Malathion inhibits the reaction [CYP2E1 protein results in increased hydroxylation of Chlorzoxazone] Malathion results in decreased activity of CYP2E1 protein
CTD
PMID:22634058
NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
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Cyp3a2
cytochrome P450, family 3, subfamily a, polypeptide 2
multiple interactions affects metabolic processing increases expression
ISO
[Malathion co-treated with isomalathion] results in increased expression of CYP3A4 mRNA CYP3A4 protein affects the metabolism of Malathion Malathion results in increased expression of CYP3A4 mRNA
CTD
PMID:15557345 PMID:17110060 PMID:22310298 PMID:24333466
NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008
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Cyp3a9
cytochrome P450, family 3, subfamily a, polypeptide 9
affects metabolic processing increases expression
ISO
CYP3A5 protein affects the metabolism of Malathion Malathion results in increased expression of CYP3A5 mRNA
CTD
PMID:17110060 PMID:37047231
NCBI chr12:16,806,222...16,846,428
Ensembl chr12:16,806,207...16,846,422
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Cyp8b1
cytochrome P450 family 8 subfamily B member 1
multiple interactions
ISO
[Insecticides results in increased abundance of Malathion] which affects the methylation of CYP8B1 gene
CTD
PMID:34516295
NCBI chr 8:121,578,123...121,580,093
Ensembl chr 8:121,557,062...121,580,166
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Dcn
decorin
increases expression
ISO
Malathion results in increased expression of DCN mRNA
CTD
PMID:37047231
NCBI chr 7:32,281,252...32,321,291
Ensembl chr 7:32,281,252...32,321,270
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Ddc
dopa decarboxylase
affects binding increases expression
ISO
Malathion binds to [DDC protein binds to Pyridoxal Phosphate]; Malathion binds to DDC protein Malathion results in increased expression of DDC mRNA
CTD
PMID:35151785 PMID:37047231
NCBI chr14:86,378,685...86,469,189
Ensembl chr14:86,378,685...86,469,208
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Ddr1
discoidin domain receptor tyrosine kinase 1
decreases expression
ISO
Malathion results in decreased expression of DDR1 mRNA
CTD
PMID:37047231
NCBI chr20:3,042,494...3,064,442
Ensembl chr20:3,044,320...3,064,468
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Ddx11
DEAD/H-box helicase 11
increases expression
ISO
Malathion results in increased expression of DDX11 mRNA
CTD
PMID:32069766
NCBI chr 9:105,833,234...105,862,844
Ensembl chr 9:105,833,504...105,862,550
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Dio1
iodothyronine deiodinase 1
decreases expression
ISO
Malathion results in decreased expression of DIO1 mRNA
CTD
PMID:37047231
NCBI chr 5:122,074,285...122,090,983
Ensembl chr 5:122,074,279...122,090,970
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Disc1
DISC1 scaffold protein
increases expression
ISO
Malathion results in increased expression of DISC1 mRNA
CTD
PMID:37047231
NCBI chr19:53,014,201...53,223,617
Ensembl chr19:53,014,616...53,219,778
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Dkk2
dickkopf WNT signaling pathway inhibitor 2
increases expression
ISO
Malathion results in increased expression of DKK2 mRNA
CTD
PMID:37047231
NCBI chr 2:220,568,338...220,660,225
Ensembl chr 2:220,568,338...220,660,225
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Dlg2
discs large MAGUK scaffold protein 2
increases expression
ISO
Malathion results in increased expression of DLG2 mRNA
CTD
PMID:37047231
NCBI chr 1:144,451,653...146,503,949
Ensembl chr 1:144,451,472...146,499,475
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Dnmt1
DNA methyltransferase 1
decreases expression
EXP
Malathion results in decreased expression of DNMT1 mRNA
CTD
PMID:36370973
NCBI chr 8:19,440,611...19,486,659
Ensembl chr 8:19,440,611...19,486,659
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Dnmt3a
DNA methyltransferase 3 alpha
affects expression
EXP
Malathion affects the expression of DNMT3A mRNA
CTD
PMID:36370973
NCBI chr 6:26,791,517...26,902,161
Ensembl chr 6:26,822,609...26,896,687
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Dnmt3b
DNA methyltransferase 3 beta
affects expression
EXP
Malathion affects the expression of DNMT3B mRNA
CTD
PMID:36370973
NCBI chr 3:142,130,588...142,169,128
Ensembl chr 3:142,130,592...142,169,124
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Doc2b
double C2 domain beta
decreases expression
ISO
Malathion results in decreased expression of DOC2B mRNA
CTD
PMID:37047231
NCBI chr10:60,628,029...60,653,267
Ensembl chr10:60,628,029...60,653,267
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Dsp
desmoplakin
increases expression
ISO
Malathion results in increased expression of DSP mRNA
CTD
PMID:37047231
NCBI chr17:26,623,602...26,671,692
Ensembl chr17:26,623,588...26,671,800
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Dspp
dentin sialophosphoprotein
decreases expression
ISO
Malathion results in decreased expression of DSPP mRNA
CTD
PMID:37047231
NCBI chr14:5,565,562...5,571,669
Ensembl chr14:5,565,629...5,571,672
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Dtna
dystrobrevin, alpha
decreases expression
ISO
Malathion results in decreased expression of DTNA mRNA
CTD
PMID:37047231
NCBI chr18:14,687,193...14,944,232
Ensembl chr18:14,587,852...14,944,261
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Duox1
dual oxidase 1
multiple interactions increases expression
ISO
Plant Extracts inhibits the reaction [Malathion results in increased expression of DUOX1 protein]; Polyphenols inhibits the reaction [Malathion results in increased expression of DUOX1 protein]
CTD
PMID:32120800
NCBI chr 3:109,260,526...109,295,588
Ensembl chr 3:109,262,397...109,295,563
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Dusp1
dual specificity phosphatase 1
decreases expression
ISO
Malathion results in decreased expression of DUSP1 mRNA
CTD
PMID:32069766
NCBI chr10:16,680,478...16,683,275
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Dusp5
dual specificity phosphatase 5
increases expression
ISO
Malathion results in increased expression of DUSP5 mRNA
CTD
PMID:37047231
NCBI chr 1:252,538,408...252,555,320
Ensembl chr 1:252,538,449...252,551,818
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Dvl1
dishevelled segment polarity protein 1
increases expression
ISO
Malathion results in increased expression of DVL1 mRNA
CTD
PMID:18204794
NCBI chr 5:166,456,989...166,468,733
Ensembl chr 5:166,456,686...166,468,664
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Ebi3
Epstein-Barr virus induced 3
increases expression
ISO
Malathion results in increased expression of EBI3 mRNA
CTD
PMID:37047231
NCBI chr 9:774,252...787,544
Ensembl chr 9:783,617...787,544
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Edn1
endothelin 1
increases expression
ISO
Malathion results in increased expression of EDN1 mRNA
CTD
PMID:37047231
NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885
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Ednrb
endothelin receptor type B
decreases expression
ISO
Malathion results in decreased expression of EDNRB mRNA
CTD
PMID:37047231
NCBI chr15:80,640,839...80,672,115
Ensembl chr15:80,643,043...80,672,115
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Efcab9
EF-hand calcium binding domain 9
increases expression
ISO
Malathion results in increased expression of EFCAB9 mRNA
CTD
PMID:37047231
NCBI chr10:17,107,123...17,112,282
Ensembl chr10:17,107,123...17,112,289
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Ehbp1
EH domain binding protein 1
increases response to substance
ISO
EHBP1 gene SNP results in increased susceptibility to Malathion
CTD
PMID:23593118
NCBI chr14:96,093,327...96,380,502
Ensembl chr14:96,093,327...96,345,332
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En1
engrailed homeobox 1
decreases expression
ISO
Malathion results in decreased expression of EN1 mRNA
CTD
PMID:37047231
NCBI chr13:31,750,892...31,756,477
Ensembl chr13:31,751,545...31,755,943
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Enkur
enkurin, TRPC channel interacting protein
increases expression
ISO
Malathion results in increased expression of ENKUR mRNA
CTD
PMID:37047231
NCBI chr17:83,690,105...83,714,756
Ensembl chr17:83,690,797...83,714,408
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Epha10
EPH receptor A10
increases expression
ISO
Malathion results in increased expression of EPHA10 mRNA
CTD
PMID:37047231
NCBI chr 5:137,139,588...137,175,637
Ensembl chr 5:137,140,735...137,174,157
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Epha4
Eph receptor A4
increases expression
ISO
Malathion results in increased expression of EPHA4 mRNA
CTD
PMID:32069766
NCBI chr 9:78,815,460...78,958,139
Ensembl chr 9:78,815,460...78,958,139
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Ephx1
epoxide hydrolase 1
decreases expression
ISO
Malathion results in decreased expression of EPHX1 mRNA
CTD
PMID:17311802
NCBI chr13:92,714,315...92,744,105
Ensembl chr13:92,714,315...92,790,235
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Epop
elongin BC and polycomb repressive complex 2 associated protein
increases expression
ISO
Malathion results in increased expression of EPOP mRNA
CTD
PMID:37047231
NCBI chr10:82,624,392...82,625,912
Ensembl chr10:82,624,392...82,625,912
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Eps8l1
EPS8-like 1
increases expression
ISO
Malathion results in increased expression of EPS8L1 mRNA
CTD
PMID:32069766
NCBI chr 1:69,343,202...69,359,778
Ensembl chr 1:69,344,243...69,363,524
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Erbb4
erb-b2 receptor tyrosine kinase 4
increases expression
ISO
Malathion results in increased expression of ERBB4 mRNA
CTD
PMID:37047231
NCBI chr 9:69,523,733...70,596,743
Ensembl chr 9:69,531,481...70,596,595
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Esr1
estrogen receptor 1
decreases activity
ISO
Malathion results in decreased activity of ESR1 protein
CTD
PMID:22562034
NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
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Etv6
ETS variant transcription factor 6
increases expression
ISO
Malathion results in increased expression of ETV6 mRNA mutant form
CTD
PMID:28624474
NCBI chr 4:166,849,031...167,085,211
Ensembl chr 4:166,847,686...167,084,992
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F3
coagulation factor III, tissue factor
increases expression
ISO
Malathion results in increased expression of F3 mRNA
CTD
PMID:37047231
NCBI chr 2:209,827,061...209,838,666
Ensembl chr 2:209,826,959...209,838,668
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Fam124a
family with sequence similarity 124 member A
increases expression
ISO
Malathion results in increased expression of FAM124A mRNA
CTD
PMID:37047231
NCBI chr15:36,799,836...36,855,062
Ensembl chr15:36,799,877...36,853,683
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Fam227b
family with sequence similarity 227, member B
decreases expression
ISO
Malathion results in decreased expression of FAM227B mRNA
CTD
PMID:37047231
NCBI chr 3:113,226,662...113,392,396
Ensembl chr 3:113,233,205...113,392,320
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Fam229b
family with sequence similarity 229, member B
decreases expression
ISO
Malathion results in decreased expression of FAM229B mRNA
CTD
PMID:37047231
NCBI chr20:42,538,853...42,552,355
Ensembl chr20:42,538,868...42,552,248
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Fgf22
fibroblast growth factor 22
decreases expression
ISO
Malathion results in decreased expression of FGF22 mRNA
CTD
PMID:37047231
NCBI chr 7:9,947,632...9,956,918
Ensembl chr 7:9,948,071...9,950,486
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Fgf6
fibroblast growth factor 6
increases expression
ISO
Malathion results in increased expression of FGF6 mRNA
CTD
PMID:32069766
NCBI chr 4:159,854,913...159,863,447
Ensembl chr 4:159,854,913...159,863,447
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Fgfbp1
fibroblast growth factor binding protein 1
increases expression
ISO
Malathion results in increased expression of FGFBP1 mRNA
CTD
PMID:37047231
NCBI chr14:67,103,686...67,107,492
Ensembl chr14:67,104,545...67,107,496
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Fgfr1
Fibroblast growth factor receptor 1
increases expression
ISO
Malathion results in increased expression of FGFR1 mRNA
CTD
PMID:32069766
NCBI chr16:66,491,930...66,547,161
Ensembl chr16:66,494,042...66,547,350
G
Fgg
fibrinogen gamma chain
decreases expression
ISO
Malathion results in decreased expression of FGG mRNA
CTD
PMID:37047231
NCBI chr 2:168,354,880...168,362,325
Ensembl chr 2:168,355,013...168,362,322
G
Filip1l
filamin A interacting protein 1-like
increases expression
ISO
Malathion results in increased expression of FILIP1L mRNA
CTD
PMID:37047231
NCBI chr11:42,937,353...43,177,085
Ensembl chr11:42,940,467...43,177,415
G
Flt4
Fms related receptor tyrosine kinase 4
increases expression
ISO
Malathion results in increased expression of FLT4 mRNA
CTD
PMID:37047231
NCBI chr10:33,913,725...33,954,770
Ensembl chr10:33,913,608...33,954,770
G
Foxo1
forkhead box O1
decreases expression multiple interactions increases methylation
EXP
Malathion results in decreased expression of FOXO1 mRNA [Malathion results in increased methylation of FOXO1 promoter] which results in decreased expression of FOXO1 mRNA
CTD
PMID:36370973
NCBI chr 2:136,312,168...136,390,603
Ensembl chr 2:136,312,168...136,387,790
G
Foxo4
forkhead box O4
increases expression
ISO
Malathion results in increased expression of FOXO4 mRNA
CTD
PMID:32069766
NCBI chr X:66,385,241...66,392,115
Ensembl chr X:66,385,558...66,392,115
G
Fshr
follicle stimulating hormone receptor
increases expression
ISO
Malathion results in increased expression of FSHR mRNA
CTD
PMID:32069766
NCBI chr 6:5,198,825...5,406,785
Ensembl chr 6:5,198,825...5,406,785
G
G6pd
glucose-6-phosphate dehydrogenase
multiple interactions increases activity
EXP
[Malathion co-treated with Carbaryl] results in increased activity of G6PD protein; Plant Extracts inhibits the reaction [[Malathion co-treated with Carbaryl] results in increased activity of G6PD protein] Malathion results in increased activity of G6PD protein
CTD
PMID:27214522
NCBI chr X:152,201,081...152,220,863
Ensembl chr X:152,201,098...152,220,801
G
Gad1
glutamate decarboxylase 1
affects binding
ISO
Malathion binds to [GAD1 protein binds to Pyridoxal Phosphate]; Malathion binds to GAD1 protein
CTD
PMID:35151785
NCBI chr 3:55,369,704...55,410,335
Ensembl chr 3:55,369,704...55,410,333
G
Gad2
glutamate decarboxylase 2
affects binding
ISO
Malathion binds to [GAD2 protein binds to Pyridoxal Phosphate]; Malathion binds to GAD2 protein
CTD
PMID:35151785
NCBI chr17:84,763,630...84,826,155
Ensembl chr17:84,763,628...84,826,155
G
Galnt16
polypeptide N-acetylgalactosaminyltransferase 16
increases expression
ISO
Malathion results in increased expression of GALNT16 mRNA
CTD
PMID:37047231
NCBI chr 6:100,168,943...100,250,718
Ensembl chr 6:100,170,306...100,250,705
G
Garin2
golgi associated RAB2 interactor family member 2
decreases expression
ISO
Malathion results in decreased expression of GARIN2 mRNA
CTD
PMID:37047231
NCBI chr 6:97,489,562...97,534,729
Ensembl chr 6:97,490,368...97,534,763
G
Gas2
growth arrest-specific 2
increases expression
ISO
Malathion results in increased expression of GAS2 mRNA
CTD
PMID:37047231
NCBI chr 1:101,452,361...101,582,619
Ensembl chr 1:101,482,591...101,582,619
G
Gata4
GATA binding protein 4
decreases expression
ISO
Malathion results in decreased expression of GATA4 mRNA
CTD
PMID:37047231
NCBI chr15:37,459,601...37,531,291
Ensembl chr15:37,459,601...37,505,636
G
Gbp1
guanylate binding protein 1
increases expression
ISO
Malathion results in increased expression of GBP1 mRNA
CTD
PMID:37047231
NCBI chr 2:231,398,136...231,432,773
Ensembl chr 2:231,398,163...231,432,131 Ensembl chr 2:231,398,163...231,432,131
G
Gbp3
guanylate binding protein 3
increases expression
ISO
Malathion results in increased expression of GBP3 mRNA
CTD
PMID:37047231
NCBI chr 2:231,460,032...231,500,266
Ensembl chr 2:231,486,062...231,493,098
G
Gbp5
guanylate binding protein 5
increases expression
ISO
Malathion results in increased expression of GBP5 mRNA
CTD
PMID:37047231
NCBI chr 2:231,237,748...231,257,071
Ensembl chr 2:231,237,748...231,257,061
G
Gk
glycerol kinase
multiple interactions increases activity
EXP
Acetylcysteine inhibits the reaction [Malathion results in increased activity of GK protein]
CTD
PMID:25449180
NCBI chr X:50,162,089...50,238,707
Ensembl chr X:50,163,123...50,238,631
G
Gk2
glycerol kinase 2
decreases expression
EXP
Malathion results in decreased expression of GK2 mRNA
CTD
PMID:25449180
NCBI chr14:12,107,071...12,108,923
Ensembl chr14:12,107,020...12,128,473
G
Gmnc
geminin coiled-coil domain containing
increases expression
ISO
Malathion results in increased expression of GMNC mRNA
CTD
PMID:37047231
NCBI chr11:73,836,255...73,847,698
Ensembl chr11:73,814,533...73,847,328
G
Gnai1
G protein subunit alpha i1
increases expression
ISO
Malathion results in increased expression of GNAI1 mRNA
CTD
PMID:37047231
NCBI chr 4:16,814,000...16,898,119
Ensembl chr 4:16,814,001...16,896,417
G
Gnai2
G protein subunit alpha i2
decreases expression
ISO
Malathion results in decreased expression of GNAI2 mRNA
CTD
PMID:32069766
NCBI chr 8:108,288,401...108,309,009
Ensembl chr 8:108,288,401...108,308,979
G
Got1
glutamic-oxaloacetic transaminase 1
multiple interactions increases activity
EXP
thymoquinone inhibits the reaction [Malathion results in increased activity of GOT1 protein]
CTD
PMID:33510276
NCBI chr 1:242,357,293...242,381,535
Ensembl chr 1:242,357,306...242,380,633
G
Got1l1
glutamic-oxaloacetic transaminase 1-like 1
increases expression
ISO
Malathion results in increased expression of GOT1L1 mRNA
CTD
PMID:37047231
NCBI chr16:64,860,308...64,873,656
Ensembl chr16:64,860,704...64,866,162
G
Gp5
glycoprotein V (platelet)
increases expression
ISO
Malathion results in increased expression of GP5 mRNA
CTD
PMID:37047231
NCBI chr11:70,443,613...70,446,705
Ensembl chr11:70,443,613...70,446,705
G
Gpr179
G protein-coupled receptor 179
decreases expression
ISO
Malathion results in decreased expression of GPR179 mRNA
CTD
PMID:37047231
NCBI chr10:82,324,568...82,340,448
Ensembl chr10:82,337,771...82,340,448
G
Gps2
G protein pathway suppressor 2
decreases expression
ISO
Malathion results in decreased expression of GPS2 mRNA
CTD
PMID:32069766
NCBI chr10:54,637,360...54,640,542
Ensembl chr10:54,637,455...54,640,650
G
Gpt
glutamic--pyruvic transaminase
increases activity multiple interactions
EXP
Malathion results in increased activity of GPT protein thymoquinone inhibits the reaction [Malathion results in increased activity of GPT protein]
CTD
PMID:25180440 PMID:33510276 PMID:36370973
NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494
G
Gramd4
GRAM domain containing 4
decreases expression
ISO
Malathion results in decreased expression of GRAMD4 mRNA
CTD
PMID:32069766
NCBI chr 7:117,150,398...117,224,056
Ensembl chr 7:117,150,374...117,224,053
G
Grk1
G protein-coupled receptor kinase 1
increases expression
ISO
Malathion results in increased expression of GRK1 mRNA
CTD
PMID:37047231
NCBI chr16:76,122,501...76,135,792
Ensembl chr16:76,123,842...76,135,792
G
Gsk3b
glycogen synthase kinase 3 beta
increases expression
EXP
Malathion results in increased expression of GSK3B mRNA
CTD
PMID:25449180
NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
G
Gsr
glutathione-disulfide reductase
multiple interactions decreases activity
ISO EXP
[Hexachlorocyclohexane co-treated with Malathion] results in decreased activity of GSR protein Malathion results in decreased activity of GSR protein zinc chloride inhibits the reaction [Malathion results in decreased activity of GSR protein]
CTD
PMID:16718366 PMID:19429256
NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
G
Gstp1
glutathione S-transferase pi 1
decreases expression
ISO
Malathion results in decreased expression of GSTP1 mRNA
CTD
PMID:32069766
NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226
G
Gzmb
granzyme B
decreases expression multiple interactions
ISO
Malathion results in decreased expression of GZMB protein Plant Extracts inhibits the reaction [Malathion results in decreased expression of GZMB protein]; Polyphenols inhibits the reaction [Malathion results in decreased expression of GZMB protein]
CTD
PMID:32120800
NCBI chr15:30,343,352...30,346,814
Ensembl chr15:30,173,603...30,346,814
G
H19
H19 imprinted maternally expressed transcript
increases expression
ISO
Malathion results in increased expression of H19 mRNA
CTD
PMID:37047231
NCBI chr 1:197,730,698...197,733,374
Ensembl chr 1:197,730,698...197,733,134
G
Has1
hyaluronan synthase 1
increases expression
ISO
Malathion results in increased expression of HAS1 mRNA
CTD
PMID:37047231
NCBI chr 1:58,693,411...58,705,653
Ensembl chr 1:58,693,411...58,705,397
G
Hbegf
heparin-binding EGF-like growth factor
increases expression
ISO
Malathion results in increased expression of HBEGF mRNA
CTD
PMID:37047231
NCBI chr18:28,106,284...28,116,167
Ensembl chr18:28,105,760...28,116,441
G
Hdc
histidine decarboxylase
affects binding
ISO
Malathion binds to [HDC protein binds to Pyridoxal Phosphate]; Malathion binds to HDC protein
CTD
PMID:35151785
NCBI chr 3:113,847,256...113,865,334
Ensembl chr 3:113,847,260...113,865,341
G
Hilpda
hypoxia inducible lipid droplet-associated
increases expression
ISO
Malathion results in increased expression of HILPDA mRNA
CTD
PMID:37047231
NCBI chr 4:57,871,088...57,874,048
Ensembl chr 4:57,871,110...57,874,557
G
Hmox1
heme oxygenase 1
increases expression
EXP
Malathion results in increased expression of HMOX1 protein
CTD
PMID:34778934
NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
G
Hnmt
histamine N-methyltransferase
decreases expression
ISO
Malathion results in decreased expression of HNMT mRNA
CTD
PMID:37047231
NCBI chr 3:6,591,804...6,623,821
Ensembl chr 3:6,591,463...6,624,012
G
Hras
HRas proto-oncogene, GTPase
multiple interactions increases expression
ISO
[Malathion co-treated with Estrogens] results in increased expression of HRAS mRNA Malathion results in increased expression of HRAS mRNA; Malathion results in increased expression of HRAS protein
CTD
PMID:18204794 PMID:19787260
NCBI chr 1:196,290,127...196,299,823
Ensembl chr 1:196,296,263...196,300,615
G
Hsd17b3
hydroxysteroid (17-beta) dehydrogenase 3
multiple interactions decreases expression
ISO EXP
lavender oil inhibits the reaction [Malathion results in decreased expression of HSD17B3 mRNA]
CTD
PMID:30409133 PMID:36336997
NCBI chr17:1,027,229...1,058,554
Ensembl chr17:1,027,229...1,058,554
G
Hsf2bp
heat shock transcription factor 2 binding protein
increases expression
ISO
Malathion results in increased expression of HSF2BP mRNA
CTD
PMID:37047231
NCBI chr20:10,035,562...10,123,059
Ensembl chr20:10,035,562...10,121,242
G
Hspb2
heat shock protein family B (small) member 2
increases expression
ISO
Malathion results in increased expression of HSPB2 protein
CTD
PMID:19607909
NCBI chr 8:51,093,267...51,094,528
Ensembl chr 8:51,081,342...51,094,533
G
Htatip2
HIV-1 Tat interactive protein 2
decreases expression
ISO
Malathion results in decreased expression of HTATIP2 mRNA
CTD
PMID:32069766
NCBI chr 1:99,473,411...99,488,632
Ensembl chr 1:99,469,245...99,488,629
G
Htra4
HtrA serine peptidase 4
decreases expression
ISO
Malathion results in decreased expression of HTRA4 mRNA
CTD
PMID:37047231
NCBI chr16:67,001,605...67,015,074
Ensembl chr16:67,001,605...67,015,074
G
Ido1
indoleamine 2,3-dioxygenase 1
increases expression
ISO
Malathion results in increased expression of IDO1 mRNA
CTD
PMID:37047231
NCBI chr16:67,430,654...67,442,726
Ensembl chr16:67,430,578...67,442,730
G
Ifi44l
interferon-induced protein 44-like
increases expression
ISO
Malathion results in increased expression of IFI44L mRNA
CTD
PMID:37047231
NCBI chr 2:240,668,742...240,706,425
Ensembl chr 2:240,668,713...240,706,359
G
Ifnb1
interferon beta 1
multiple interactions
ISO
Malathion inhibits the reaction [Lipopolysaccharides results in increased expression of IFNB1 mRNA]
CTD
PMID:18177342
NCBI chr 5:103,020,758...103,021,595
Ensembl chr 5:103,020,969...103,021,523
G
Ifng
interferon gamma
decreases expression multiple interactions increases expression
EXP ISO
Malathion results in decreased expression of IFNG protein Acetylcysteine inhibits the reaction [Malathion results in increased expression of IFNG mRNA]; Taurine inhibits the reaction [Malathion results in increased expression of IFNG mRNA] Plant Extracts inhibits the reaction [Malathion results in decreased expression of IFNG protein]; Polyphenols inhibits the reaction [Malathion results in decreased expression of IFNG protein]
CTD
PMID:19145326 PMID:24810974 PMID:25180440 PMID:28987951 PMID:32120800
NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
G
Il11
interleukin 11
increases expression
ISO
Malathion results in increased expression of IL11 mRNA
CTD
PMID:37047231
NCBI chr 1:69,069,829...69,076,129
Ensembl chr 1:69,068,137...69,076,129
G
Il13
interleukin 13
increases expression
ISO
Malathion results in increased expression of IL13 mRNA
CTD
PMID:37047231
NCBI chr10:37,790,130...37,792,687
Ensembl chr10:37,790,130...37,792,737
G
Il13ra2
interleukin 13 receptor subunit alpha 2
increases expression
ISO
Malathion results in increased expression of IL13RA2 mRNA
CTD
PMID:32069766
NCBI chr X:111,002,590...111,074,053
Ensembl chr X:111,002,592...111,072,381
G
Il1a
interleukin 1 alpha
increases expression
ISO
Malathion results in increased expression of IL1A mRNA
CTD
PMID:37047231
NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
G
Il1b
interleukin 1 beta
multiple interactions increases expression
EXP ISO
Acetylcysteine inhibits the reaction [Malathion results in increased expression of IL1B mRNA]; Taurine inhibits the reaction [Malathion results in increased expression of IL1B mRNA]
CTD
PMID:24810974 PMID:25180440 PMID:28987951 PMID:37047231
NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
G
Il1r2
interleukin 1 receptor type 2
decreases expression
EXP
Malathion results in decreased expression of IL1R2 mRNA
CTD
PMID:19784758
NCBI chr 9:42,384,280...42,424,726
Ensembl chr 9:42,384,433...42,424,725
G
Il2
interleukin 2
multiple interactions decreases expression
ISO
Plant Extracts inhibits the reaction [Malathion results in decreased expression of IL2 protein]; Polyphenols inhibits the reaction [Malathion results in decreased expression of IL2 protein]
CTD
PMID:32120800
NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566
G
Il23a
interleukin 23 subunit alpha
increases expression
ISO
Malathion results in increased expression of IL23A mRNA
CTD
PMID:37047231
NCBI chr 7:721,809...723,923
Ensembl chr 7:721,809...723,923
G
Il24
interleukin 24
increases expression
ISO
Malathion results in increased expression of IL24 mRNA
CTD
PMID:37047231
NCBI chr13:42,353,089...42,358,487
Ensembl chr13:42,353,090...42,358,487
G
Il36g
interleukin 36, gamma
increases expression
ISO
Malathion results in increased expression of IL36G mRNA
CTD
PMID:37047231
NCBI chr 3:6,948,323...6,954,485
Ensembl chr 3:6,948,297...6,954,480
G
Il4
interleukin 4
decreases expression multiple interactions
ISO
Malathion results in decreased expression of IL4 protein Plant Extracts inhibits the reaction [Malathion results in decreased expression of IL4 protein]; Polyphenols inhibits the reaction [Malathion results in decreased expression of IL4 protein]
CTD
PMID:32120800
NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
G
Il6
interleukin 6
multiple interactions increases expression
EXP ISO
Acetylcysteine inhibits the reaction [Malathion results in increased expression of IL6 mRNA]
CTD
PMID:24810974 PMID:25180440 PMID:37047231
NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
G
Inhba
inhibin subunit beta A
increases expression decreases methylation
ISO
Malathion results in increased expression of INHBA mRNA Malathion results in decreased methylation of INHBA promoter
CTD
PMID:37047231
NCBI chr17:49,091,635...49,111,573
Ensembl chr17:49,095,920...49,108,982
G
Ins1
insulin 1
increases expression
EXP
Malathion results in increased expression of INS1 protein
CTD
PMID:25449180
NCBI chr 1:251,244,973...251,245,540
Ensembl chr 1:251,244,973...251,245,536
G
Irak1
interleukin-1 receptor-associated kinase 1
increases expression
ISO
Malathion results in increased expression of IRAK1 mRNA
CTD
PMID:32069766
NCBI chr X:151,768,621...151,778,521
Ensembl chr X:151,768,777...151,778,521
G
Irak2
interleukin-1 receptor-associated kinase 2
increases expression
ISO
Malathion results in increased expression of IRAK2 mRNA
CTD
PMID:37047231
NCBI chr 4:146,786,004...146,842,615
Ensembl chr 4:146,786,100...146,842,602
G
Irx2
iroquois homeobox 2
increases expression
ISO
Malathion results in increased expression of IRX2 mRNA
CTD
PMID:37047231
NCBI chr 1:30,660,960...30,666,378
Ensembl chr 1:30,660,960...30,666,378
G
Itgb8
integrin subunit beta 8
decreases methylation increases expression
ISO
Malathion results in decreased methylation of ITGB8 promoter Malathion results in increased expression of ITGB8 mRNA
CTD
PMID:37047231
NCBI chr 6:140,125,002...140,208,261
Ensembl chr 6:140,127,203...140,208,476
G
Kazn
kazrin, periplakin interacting protein
decreases expression
ISO
Malathion results in decreased expression of KAZN mRNA
CTD
PMID:37047231
NCBI chr 5:154,392,793...155,381,567
Ensembl chr 5:154,392,793...154,779,074
G
Kcnh5
potassium voltage-gated channel subfamily H member 5
increases expression
ISO
Malathion results in increased expression of KCNH5 mRNA
CTD
PMID:37047231
NCBI chr 6:93,615,174...93,908,107
Ensembl chr 6:93,624,529...93,908,107
G
Kcnma1
potassium calcium-activated channel subfamily M alpha 1
increases methylation decreases expression
ISO
Malathion results in increased methylation of KCNMA1 promoter Malathion results in decreased expression of KCNMA1 mRNA
CTD
PMID:37047231
NCBI chr15:302,480...1,007,675
Ensembl chr15:302,214...1,001,198
G
Kif6
kinesin family member 6
decreases expression
ISO
Malathion results in decreased expression of KIF6 mRNA
CTD
PMID:37047231
NCBI chr 9:11,076,203...11,373,205
Ensembl chr 9:11,072,824...11,373,006
G
Kit
KIT proto-oncogene receptor tyrosine kinase
increases expression multiple interactions
EXP
Malathion results in increased expression of KIT protein Rosmarinic Acid inhibits the reaction [Malathion results in increased expression of KIT protein]; thymoquinone inhibits the reaction [Malathion results in increased expression of KIT protein]
CTD
PMID:33510276 PMID:34262720
NCBI chr14:32,547,459...32,624,694
Ensembl chr14:32,548,877...32,624,652
G
Kmt2a
lysine methyltransferase 2A
increases mutagenesis increases expression
ISO
Malathion results in increased mutagenesis of KMT2A gene Malathion results in increased expression of KMT2A mRNA mutant form
CTD
PMID:28624474
NCBI chr 8:45,116,763...45,193,320
Ensembl chr 8:45,118,814...45,193,181
G
Krt14
keratin 14
increases expression
ISO
Malathion results in increased expression of KRT14 mRNA
CTD
PMID:37047231
NCBI chr10:85,137,786...85,142,054
Ensembl chr10:85,066,802...85,171,799
G
Krt17
keratin 17
increases expression
ISO
Malathion results in increased expression of KRT17 mRNA
CTD
PMID:37047231
NCBI chr10:85,178,673...85,183,392
Ensembl chr10:85,178,675...85,183,392
G
Krtap27-1
keratin associated protein 27-1
increases expression
ISO
Malathion results in increased expression of KRTAP27-1 mRNA
CTD
PMID:37047231
NCBI chr11:27,980,875...27,982,002
G
L1td1
LINE-1 type transposase domain containing 1
affects expression increases methylation multiple interactions
EXP
Malathion affects the expression of L1TD1 mRNA Malathion results in increased methylation of L1TD1 promoter [Malathion results in increased methylation of L1TD1 promoter] which affects the expression of L1TD1 mRNA
CTD
PMID:36370973
NCBI chr 5:113,373,193...113,386,088
Ensembl chr 5:113,379,870...113,385,730
G
Lat
linker for activation of T cells
increases expression
EXP
Malathion results in increased expression of LAT mRNA
CTD
PMID:19784758
NCBI chr 1:180,936,536...180,941,561
Ensembl chr 1:180,936,534...180,941,578
G
Lcorl
ligand dependent nuclear receptor corepressor-like
increases expression
ISO
Malathion results in increased expression of LCORL mRNA
CTD
PMID:37047231
NCBI chr14:65,271,339...65,407,732
Ensembl chr14:65,271,135...65,404,174
G
Lemd1
LEM domain containing 1
increases expression
ISO
Malathion results in increased expression of LEMD1 mRNA
CTD
PMID:37047231
NCBI chr13:43,631,705...43,697,765
Ensembl chr13:43,665,926...43,697,948
G
Lgals1
galectin 1
decreases expression
ISO
Malathion results in decreased expression of LGALS1 mRNA
CTD
PMID:32069766
NCBI chr 7:110,485,239...110,488,345
Ensembl chr 7:110,481,392...110,488,345
G
Lif
LIF, interleukin 6 family cytokine
increases expression
ISO
Malathion results in increased expression of LIF mRNA
CTD
PMID:37047231
NCBI chr14:79,131,049...79,140,486
Ensembl chr14:79,134,574...79,140,482
G
Lin28b
lin-28 homolog B
increases expression
ISO
Malathion results in increased expression of LIN28B mRNA
CTD
PMID:37047231
NCBI chr20:48,865,329...48,964,769
Ensembl chr20:48,869,485...48,955,077
G
Lingo1
leucine rich repeat and Ig domain containing 1
decreases expression
ISO
Malathion results in decreased expression of LINGO1 mRNA
CTD
PMID:37047231
NCBI chr 8:57,011,272...57,193,496
Ensembl chr 8:57,010,007...57,196,544
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Lmbr1
limb development membrane protein 1
increases expression
ISO
Malathion results in increased expression of LMBR1 mRNA
CTD
PMID:37047231
NCBI chr 4:5,974,687...6,146,348
Ensembl chr 4:5,974,750...6,146,368
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LOC120095955
mucin-12-like
decreases expression
ISO
Malathion results in decreased expression of MUC12 mRNA
CTD
PMID:37047231
NCBI chr12:19,486,041...19,493,995
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Lpcat4
lysophosphatidylcholine acyltransferase 4
increases expression
ISO
Malathion results in increased expression of LPCAT4 mRNA
CTD
PMID:32069766
NCBI chr 3:99,044,729...99,052,963
Ensembl chr 3:99,044,729...99,052,875
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Lrguk
leucine-rich repeats and guanylate kinase domain containing
decreases expression
ISO
Malathion results in decreased expression of LRGUK mRNA
CTD
PMID:37047231
NCBI chr 4:62,647,222...62,770,268
Ensembl chr 4:62,647,264...62,770,319
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Lrp3
LDL receptor related protein 3
decreases expression
ISO
Malathion results in decreased expression of LRP3 mRNA
CTD
PMID:37047231
NCBI chr 1:87,843,815...87,859,147
Ensembl chr 1:87,844,868...87,859,110
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Lypd1
Ly6/Plaur domain containing 1
decreases expression
ISO
Malathion results in decreased expression of LYPD1 mRNA
CTD
PMID:37047231
NCBI chr13:37,326,459...37,368,515
Ensembl chr13:37,326,464...37,368,493
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Lzts1
leucine zipper tumor suppressor 1
increases expression
ISO
Malathion results in increased expression of LZTS1 mRNA
CTD
PMID:37047231
NCBI chr16:20,542,756...20,598,204
Ensembl chr16:20,542,809...20,598,203
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Lzts2
leucine zipper tumor suppressor 2
decreases expression
ISO
Malathion results in decreased expression of LZTS2 mRNA
CTD
PMID:32069766
NCBI chr 1:243,876,665...243,888,489
Ensembl chr 1:243,880,022...243,888,423
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Macrod2
mono-ADP ribosylhydrolase 2
decreases expression
ISO
Malathion results in decreased expression of MACROD2 mRNA
CTD
PMID:37047231
NCBI chr 3:127,720,066...129,737,511
Ensembl chr 3:127,720,181...129,734,492
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Map2k3
mitogen activated protein kinase kinase 3
decreases expression
ISO
Malathion results in decreased expression of MAP2K3 mRNA
CTD
PMID:32069766
NCBI chr10:45,608,145...45,629,492
Ensembl chr10:45,607,163...45,629,492
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Marchf3
membrane associated ring-CH-type finger 3
increases expression
ISO
Malathion results in increased expression of MARCHF3 mRNA
CTD
PMID:37047231
NCBI chr18:50,237,218...50,389,343
Ensembl chr18:50,237,230...50,389,150
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Mbp
myelin basic protein
decreases expression
ISO
Malathion results in decreased expression of MBP mRNA
CTD
PMID:37047231
NCBI chr18:75,855,878...75,966,404
Ensembl chr18:75,855,878...75,966,404
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Mcm2
minichromosome maintenance complex component 2
multiple interactions increases expression
ISO
[Malathion co-treated with Estrogens] results in increased expression of MCM2 mRNA Malathion results in increased expression of MCM2 mRNA
CTD
PMID:18204794
NCBI chr 4:121,346,434...121,360,962
Ensembl chr 4:121,346,434...121,360,847
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Meis1
Meis homeobox 1
decreases expression
ISO
Malathion results in decreased expression of MEIS1 mRNA
CTD
PMID:37047231
NCBI chr14:93,155,426...93,294,373
Ensembl chr14:93,155,419...93,294,265
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Met
MET proto-oncogene, receptor tyrosine kinase
increases expression
ISO
Malathion results in increased expression of MET mRNA
CTD
PMID:37047231
NCBI chr 4:45,790,456...45,898,139
Ensembl chr 4:45,790,791...45,897,876
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Mfsd2a
MFSD2 lysolipid transporter A, lysophospholipid
increases expression
ISO
Malathion results in increased expression of MFSD2A mRNA
CTD
PMID:37047231
NCBI chr 5:135,225,801...135,240,744
Ensembl chr 5:135,225,816...135,240,690
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Mill1
MHC I like leukocyte 1
increases expression
ISO
Malathion results in increased expression of MICA mRNA
CTD
PMID:32069766
NCBI chr 1:78,372,798...78,398,932
Ensembl chr 1:78,372,802...78,398,930
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Mmp1
matrix metallopeptidase 1
increases expression
ISO
Malathion results in increased expression of MMP1 mRNA
CTD
PMID:37047231
NCBI chr 8:4,658,588...4,679,099
Ensembl chr 8:4,658,588...4,679,097
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Mmp10
matrix metallopeptidase 10
increases expression
ISO
Malathion results in increased expression of MMP10 mRNA
CTD
PMID:37047231
NCBI chr 8:4,689,840...4,697,748
Ensembl chr 8:4,689,840...4,697,748
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Mmp12
matrix metallopeptidase 12
increases expression
ISO
Malathion results in increased expression of MMP12 mRNA
CTD
PMID:37047231
NCBI chr 8:4,581,785...4,591,687
Ensembl chr 8:4,581,785...4,599,611
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Mmp3
matrix metallopeptidase 3
increases expression
ISO
Malathion results in increased expression of MMP3 mRNA
CTD
PMID:37047231
NCBI chr 8:4,640,397...4,653,963
Ensembl chr 8:4,640,416...4,653,961
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Mpo
myeloperoxidase
multiple interactions increases activity
EXP
Acetylcysteine inhibits the reaction [Malathion results in increased activity of MPO protein]
CTD
PMID:24810974 PMID:25180440
NCBI chr10:72,594,883...72,608,862
Ensembl chr10:72,594,661...72,604,819
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Mt-co1
mitochondrially encoded cytochrome c oxidase I
decreases expression
ISO
Malathion results in decreased expression of COX1 mRNA
CTD
PMID:18214912
NCBI chr MT:5,323...6,867 NCBI chr MT:5,323...6,867 NCBI chr MT:5,323...6,867 NCBI chr MT:5,323...6,867 NCBI chr MT:5,323...6,867 NCBI chr MT:5,323...6,867 NCBI chr MT:5,323...6,867 NCBI chr MT:5,323...6,867 NCBI chr MT:5,323...6,867 NCBI chr MT:5,323...6,867
Ensembl chr MT:5,323...6,867
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Mt-co3
mitochondrially encoded cytochrome c oxidase III
decreases expression
ISO
Malathion results in decreased expression of COX3 mRNA
CTD
PMID:18214912
NCBI chr MT:8,599...9,382 NCBI chr MT:8,599...9,382 NCBI chr MT:8,599...9,382 NCBI chr MT:8,599...9,382 NCBI chr MT:8,599...9,382 NCBI chr MT:8,599...9,382 NCBI chr MT:8,599...9,382 NCBI chr MT:8,599...9,382 NCBI chr MT:8,599...9,382
Ensembl chr MT:8,599...9,382
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Mt1-ps3
metallothionein 1, pseudogene 3
increases expression
ISO
Malathion results in increased expression of MT1E mRNA
CTD
PMID:37047231
NCBI chr17:74,786,652...74,787,040
Ensembl chr17:74,786,654...74,787,135
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Mt2A
metallothionein 2A
increases expression
ISO
Malathion results in increased expression of MT2A mRNA
CTD
PMID:37047231
NCBI chr19:10,832,009...10,832,783
Ensembl chr19:10,832,002...10,832,784
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Mybphl
myosin binding protein H-like
increases expression
ISO
Malathion results in increased expression of MYBPHL mRNA
CTD
PMID:37047231
NCBI chr 2:196,005,297...196,018,826
Ensembl chr 2:196,005,325...196,018,824
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Myo1b
myosin Ib
increases expression
ISO
Malathion results in increased expression of MYO1B mRNA
CTD
PMID:37047231
NCBI chr 9:49,690,043...49,852,373
Ensembl chr 9:49,690,086...49,850,798
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Myzap
myocardial zonula adherens protein
increases expression
ISO
Malathion results in increased expression of MYZAP mRNA
CTD
PMID:37047231
NCBI chr 8:72,155,817...72,243,036
Ensembl chr 8:72,131,530...72,243,036
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Ndufs7
NADH:ubiquinone oxidoreductase core subunit S7
decreases expression
ISO
Malathion results in decreased expression of NDUFS7 mRNA
CTD
PMID:37047231
NCBI chr 7:9,452,556...9,460,135
Ensembl chr 7:9,450,392...9,460,195
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Nefh
neurofilament heavy chain
affects expression increases expression
EXP
Malathion affects the expression of NEFH mRNA Malathion results in increased expression of NEFH mRNA
CTD
PMID:22954530 PMID:28385489
NCBI chr14:79,830,362...79,840,347
Ensembl chr14:79,830,362...79,840,351
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Nek10
NIMA-related kinase 10
decreases expression
ISO
Malathion results in decreased expression of NEK10 mRNA
CTD
PMID:37047231
NCBI chr15:10,387,063...10,564,177
Ensembl chr15:10,381,140...10,559,722
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Neu4
neuraminidase 4
increases expression
ISO
Malathion results in increased expression of NEU4 mRNA
CTD
PMID:37047231
NCBI chr 9:94,396,920...94,402,576
Ensembl chr 9:94,396,920...94,402,576
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Neurl3
neuralized E3 ubiquitin protein ligase 3
increases expression
ISO
Malathion results in increased expression of NEURL3 mRNA
CTD
PMID:37047231
NCBI chr 9:38,494,486...38,503,352
Ensembl chr 9:38,494,489...38,502,649
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Nfe2l2
NFE2 like bZIP transcription factor 2
increases activity
ISO
Malathion results in increased activity of NFE2L2 protein
CTD
PMID:30114225 PMID:30203046
NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737
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Nfib
nuclear factor I/B
decreases expression
ISO
Malathion results in decreased expression of NFIB mRNA
CTD
PMID:37047231
NCBI chr 5:96,759,208...96,974,001
Ensembl chr 5:96,764,653...96,975,479
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Ngf
nerve growth factor
multiple interactions
EXP
Malathion promotes the reaction [NGF protein results in increased expression of CAMK2A mRNA]; Malathion promotes the reaction [NGF protein results in increased expression of CAMK2B mRNA]
CTD
PMID:28385489
NCBI chr 2:189,901,058...189,954,452
Ensembl chr 2:189,901,058...189,954,452
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Ninj1
ninjurin 1
decreases expression
ISO
Malathion results in decreased expression of NINJ1 mRNA
CTD
PMID:32069766
NCBI chr17:15,452,804...15,461,684
Ensembl chr17:15,452,813...15,461,704
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Nnt
nicotinamide nucleotide transhydrogenase
decreases expression
ISO
Malathion results in decreased expression of NNT mRNA
CTD
PMID:37047231
NCBI chr 2:51,411,413...51,505,125
Ensembl chr 2:51,411,413...51,504,823
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Nos2
nitric oxide synthase 2
increases expression
EXP
Malathion results in increased expression of NOS2 mRNA
CTD
PMID:20233601
NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
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Nqo1
NAD(P)H quinone dehydrogenase 1
increases expression
ISO
Malathion results in increased expression of NQO1 mRNA
CTD
PMID:17311802
NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
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Nr1i3
nuclear receptor subfamily 1, group I, member 3
increases expression increases activity
ISO
Malathion results in increased expression of NR1I3 mRNA Malathion results in increased activity of NR1I3 protein
CTD
PMID:22310298 PMID:28927721 PMID:30203046
NCBI chr13:83,632,940...83,638,193
Ensembl chr13:83,632,899...83,637,906
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Nr4a1
nuclear receptor subfamily 4, group A, member 1
increases expression
ISO
Malathion results in increased expression of NR4A1 mRNA
CTD
PMID:37047231
NCBI chr 7:132,368,399...132,389,300
Ensembl chr 7:132,374,840...132,389,297
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Nr4a3
nuclear receptor subfamily 4, group A, member 3
decreases methylation increases expression
ISO
Malathion results in decreased methylation of NR4A3 promoter Malathion results in increased expression of NR4A3 mRNA
CTD
PMID:37047231
NCBI chr 5:62,361,588...62,401,489
Ensembl chr 5:62,361,822...62,402,733
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Ntn1
netrin 1
increases expression
ISO
Malathion results in increased expression of NTN1 mRNA
CTD
PMID:37047231
NCBI chr10:52,899,933...53,098,591
Ensembl chr10:52,899,934...53,085,326
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Ntrk2
neurotrophic receptor tyrosine kinase 2
increases expression
ISO
Malathion results in increased expression of NTRK2 mRNA
CTD
PMID:32069766
NCBI chr17:5,558,992...5,870,299
Ensembl chr17:5,559,043...5,869,136
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Ocln
occludin
multiple interactions decreases expression
EXP
[Malathion co-treated with Lead] results in decreased expression of OCLN protein Malathion results in decreased expression of OCLN protein
CTD
PMID:20970449
NCBI chr 2:31,657,217...31,707,466
Ensembl chr 2:31,657,220...31,764,150
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Ocstamp
osteoclast stimulatory transmembrane protein
increases expression
ISO
Malathion results in increased expression of OCSTAMP mRNA
CTD
PMID:37047231
NCBI chr 3:154,131,113...154,141,611
Ensembl chr 3:154,132,328...154,136,991
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Odam
odontogenic, ameloblast associated
decreases expression
ISO
Malathion results in decreased expression of ODAM mRNA
CTD
PMID:37047231
NCBI chr14:20,193,286...20,202,517
Ensembl chr14:20,193,302...20,202,517
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Odf2l
outer dense fiber of sperm tails 2-like
decreases expression
ISO
Malathion results in decreased expression of ODF2L mRNA
CTD
PMID:37047231
NCBI chr 2:234,036,049...234,072,751
Ensembl chr 2:234,033,652...234,072,747
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Olr1433
olfactory receptor 1433
increases expression
ISO
Malathion results in increased expression of OR2W3 mRNA
CTD
PMID:37047231
NCBI chr10:43,042,427...43,046,293
Ensembl chr10:43,037,857...43,046,701
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Olr1523
olfactory receptor 1523
decreases expression
ISO
Malathion results in decreased expression of OR4D1 mRNA
CTD
PMID:37047231
NCBI chr10:72,708,272...72,709,213
Ensembl chr10:72,707,063...72,715,311
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Olr35
olfactory receptor 35
decreases expression
ISO
Malathion results in decreased expression of OR2AT4 mRNA
CTD
PMID:37047231
NCBI chr 1:153,994,678...154,043,281
Ensembl chr 1:154,041,306...154,043,257
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Omg
oligodendrocyte-myelin glycoprotein
affects expression
ISO
Malathion affects the expression of OMG mRNA
CTD
PMID:37047231
NCBI chr10:64,461,350...64,464,084
Ensembl chr10:64,461,350...64,464,084
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Opn5
opsin 5
decreases expression
ISO
Malathion results in decreased expression of OPN5 mRNA
CTD
PMID:37047231
NCBI chr 9:18,368,393...18,416,098
Ensembl chr 9:18,368,416...18,415,476
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Or4f7c
olfactory receptor family 4 subfamily F member 7C
decreases expression
ISO
Malathion results in decreased expression of OR4F21 mRNA
CTD
PMID:37047231
NCBI chr 3:98,458,889...98,459,827
Ensembl chr 3:98,457,871...98,464,794
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Or6c2
olfactory receptor family 6 subfamily C member 2
decreases expression
ISO
Malathion results in decreased expression of OR6C2 mRNA
CTD
PMID:37047231
NCBI chr 7:2,188,601...2,189,539
Ensembl chr 7:2,182,984...2,189,667
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Or9g4
olfactory receptor family 9 subfamily G member 4
decreases expression
ISO
Malathion results in decreased expression of OR9G4 mRNA
CTD
PMID:37047231
NCBI chr 3:70,727,963...70,728,901
Ensembl chr 3:70,726,935...70,732,439
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P2rx1
purinergic receptor P2X 1
increases expression
EXP
Malathion results in increased expression of P2RX1 mRNA
CTD
PMID:19784758
NCBI chr10:57,618,586...57,633,648
Ensembl chr10:57,618,586...57,633,623
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Palmd
palmdelphin
decreases expression
ISO
Malathion results in decreased expression of PALMD mRNA
CTD
PMID:37047231
NCBI chr 2:204,889,526...204,941,355
Ensembl chr 2:204,889,533...204,941,519
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Parp1
poly (ADP-ribose) polymerase 1
increases cleavage multiple interactions
ISO
Malathion results in increased cleavage of PARP1 protein Metoclopramide inhibits the reaction [Malathion results in increased cleavage of PARP1 protein]
CTD
PMID:29027213
NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
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Pax1
paired box 1
increases expression
ISO
Malathion results in increased expression of PAX1 mRNA
CTD
PMID:32069766
NCBI chr 3:134,792,330...134,801,637
Ensembl chr 3:134,789,182...134,801,636
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Pcdh15
protocadherin related 15
decreases expression
ISO
Malathion results in decreased expression of PCDH15 mRNA
CTD
PMID:37047231
NCBI chr20:13,997,094...15,496,446
Ensembl chr20:13,963,565...15,494,719
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Pcdhb19
protocadherin beta 19
decreases expression
ISO
Malathion results in decreased expression of PCDHB12 mRNA
CTD
PMID:37047231
NCBI chr18:29,204,838...29,207,646
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Pcdhgb1
protocadherin gamma subfamily B, 1
increases expression
ISO
Malathion results in increased expression of PCDHGB1 mRNA
CTD
PMID:37047231
NCBI chr18:29,501,739...29,508,024
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Pck1
phosphoenolpyruvate carboxykinase 1
multiple interactions increases expression
EXP
Acetylcysteine inhibits the reaction [Malathion results in increased expression of PCK1 mRNA]
CTD
PMID:25449180
NCBI chr 3:161,930,256...161,936,205
Ensembl chr 3:161,930,256...161,936,191
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Pcna
proliferating cell nuclear antigen
multiple interactions increases expression
ISO
Atropine inhibits the reaction [Malathion results in increased expression of PCNA]
CTD
PMID:12762645
NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995
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Pde6c
phosphodiesterase 6C
decreases expression
ISO
Malathion results in decreased expression of PDE6C mRNA
CTD
PMID:37047231
NCBI chr 1:235,909,583...235,965,435
Ensembl chr 1:235,909,775...235,965,315
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Pdia2
protein disulfide isomerase family A, member 2
decreases expression
ISO
Malathion results in decreased expression of PDIA2 mRNA
CTD
PMID:37047231
NCBI chr10:15,215,824...15,218,937
Ensembl chr10:15,215,824...15,220,931
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Pebp1
phosphatidylethanolamine binding protein 1
decreases expression
ISO
Malathion results in decreased expression of PEBP1 mRNA
CTD
PMID:32069766
NCBI chr12:39,302,864...39,307,064
Ensembl chr12:39,302,840...39,307,862
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Peg10
paternally expressed 10
increases expression
ISO
Malathion results in increased expression of PEG10 mRNA
CTD
PMID:37047231
NCBI chr 4:32,842,441...32,855,639
Ensembl chr 4:32,848,493...32,852,621
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Pfn1
profilin 1
decreases expression
ISO
Malathion results in decreased expression of PFN1 mRNA
CTD
PMID:32069766
NCBI chr10:55,365,263...55,367,968
Ensembl chr10:55,365,262...55,527,631
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Phb1
prohibitin 1
decreases expression
ISO
Malathion results in decreased expression of PHB1 mRNA
CTD
PMID:32069766
NCBI chr10:80,605,268...80,618,043
Ensembl chr10:80,605,251...80,618,042
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Pitx1
paired-like homeodomain 1
decreases expression
ISO
Malathion results in decreased expression of PITX1 mRNA
CTD
PMID:37047231
NCBI chr17:8,794,134...8,800,292
Ensembl chr17:8,794,134...8,800,291
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Plat
plasminogen activator, tissue type
decreases expression
ISO
Malathion results in decreased expression of PLAT mRNA
CTD
PMID:16079077
NCBI chr16:69,240,582...69,265,177
Ensembl chr16:69,240,585...69,268,223
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Plau
plasminogen activator, urokinase
increases expression
ISO
Malathion results in increased expression of PLAU mRNA
CTD
PMID:32069766
NCBI chr15:3,456,230...3,462,732
Ensembl chr15:3,456,232...3,462,775
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Plaur
plasminogen activator, urokinase receptor
increases expression
ISO
Malathion results in increased expression of PLAUR mRNA
CTD
PMID:37047231
NCBI chr 1:80,053,440...80,068,384
Ensembl chr 1:80,050,324...80,068,595
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Plcb4
phospholipase C, beta 4
increases expression
ISO
Malathion results in increased expression of PLCB4 mRNA
CTD
PMID:37047231
NCBI chr 3:122,952,965...123,322,522
Ensembl chr 3:122,953,196...123,322,392
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Plekhd1
pleckstrin homology and coiled-coil domain containing D1
decreases expression
ISO
Malathion results in decreased expression of PLEKHD1 mRNA
CTD
PMID:37047231
NCBI chr 6:100,340,655...100,371,942
Ensembl chr 6:100,340,655...100,371,941
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Plin1
perilipin 1
increases expression
ISO
Malathion results in increased expression of PLIN1 mRNA
CTD
PMID:37047231
NCBI chr 1:133,664,294...133,676,854
Ensembl chr 1:133,664,892...133,676,828
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Plin2
perilipin 2
increases expression
ISO
Malathion results in increased expression of PLIN2 mRNA
CTD
PMID:37047231
NCBI chr 5:101,156,648...101,211,738
Ensembl chr 5:101,154,411...101,242,319
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Plp1
proteolipid protein 1
decreases expression
ISO
Malathion results in decreased expression of PLP1 mRNA
CTD
PMID:37047231
NCBI chr X:100,184,039...100,201,035
Ensembl chr X:100,185,767...100,201,032
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Pls3
plastin 3
increases expression
ISO
Malathion results in increased expression of PLS3 mRNA
CTD
PMID:37047231
NCBI chr X:111,589,193...111,683,908
Ensembl chr X:111,589,254...111,683,891
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Plvap
plasmalemma vesicle associated protein
decreases expression
ISO
Malathion results in decreased expression of PLVAP mRNA
CTD
PMID:37047231
NCBI chr16:18,184,985...18,197,301
Ensembl chr16:18,184,975...18,197,301
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Pml
PML nuclear body scaffold
decreases expression
ISO
Malathion results in decreased expression of PML mRNA
CTD
PMID:32069766
NCBI chr 8:58,627,347...58,661,927
Ensembl chr 8:58,628,837...58,658,971
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Ppara
peroxisome proliferator activated receptor alpha
decreases expression
ISO
Malathion results in decreased expression of PPARA mRNA
CTD
PMID:25689681
NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
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Prkd1
protein kinase D1
increases expression
ISO
Malathion results in increased expression of PRKD1 mRNA
CTD
PMID:32069766
NCBI chr 6:67,725,193...68,039,002
Ensembl chr 6:67,725,905...68,039,042
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Prox2
prospero homeobox 2
decreases expression
ISO
Malathion results in decreased expression of PROX2 mRNA
CTD
PMID:37047231
NCBI chr 6:104,731,385...104,758,619
Ensembl chr 6:104,733,002...104,742,093
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Proz
protein Z, vitamin K-dependent plasma glycoprotein
decreases expression
ISO
Malathion results in decreased expression of PROZ mRNA
CTD
PMID:37047231
NCBI chr16:76,450,013...76,463,558
Ensembl chr16:76,450,013...76,463,480
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Ptcra
pre T-cell antigen receptor alpha
decreases expression
ISO
Malathion results in decreased expression of PTCRA mRNA
CTD
PMID:37047231
NCBI chr 9:14,218,907...14,229,141
Ensembl chr 9:14,218,802...14,229,235
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Ptgs2
prostaglandin-endoperoxide synthase 2
increases expression
ISO
Malathion results in increased expression of PTGS2 mRNA; Malathion results in increased expression of PTGS2 protein
CTD
PMID:30673264
NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
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Pygl
glycogen phosphorylase L
multiple interactions increases expression
EXP
Acetylcysteine inhibits the reaction [Malathion results in increased expression of PYGL mRNA]
CTD
PMID:25449180
NCBI chr 6:88,697,598...88,740,260
Ensembl chr 6:88,697,593...88,740,310
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Rab11fip3
RAB11 family interacting protein 3
increases expression
ISO
Malathion results in increased expression of RAB11FIP3 mRNA
CTD
PMID:32069766
NCBI chr10:15,002,650...15,086,382
Ensembl chr10:15,002,926...15,118,479
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Rab3c
RAB3C, member RAS oncogene family
decreases expression
ISO
Malathion results in decreased expression of RAB3C mRNA
CTD
PMID:37047231
NCBI chr 2:41,627,720...41,843,541
Ensembl chr 2:41,627,720...41,843,749
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Rapgef5
Rap guanine nucleotide exchange factor 5
increases expression
ISO
Malathion results in increased expression of RAPGEF5 mRNA
CTD
PMID:37047231
NCBI chr 6:138,445,184...138,679,943
Ensembl chr 6:138,437,991...138,679,936
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Rbp3
retinol binding protein 3
decreases expression
ISO
Malathion results in decreased expression of RBP3 mRNA
CTD
PMID:37047231
NCBI chr16:9,267,538...9,276,006
Ensembl chr16:9,267,538...9,276,006
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Rbp7
retinol binding protein 7
decreases expression
ISO
Malathion results in decreased expression of RBP7 mRNA
CTD
PMID:37047231
NCBI chr 5:159,889,723...159,894,338
Ensembl chr 5:159,889,723...159,894,339
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Redic1
regulator of DNA class I crossover intermediates 1
decreases expression
ISO
Malathion results in decreased expression of REDIC1 mRNA
CTD
PMID:37047231
NCBI chr 7:122,318,495...122,386,002
Ensembl chr 7:122,318,499...122,385,983
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Rela
RELA proto-oncogene, NF-kB subunit
increases expression multiple interactions
EXP ISO
Malathion results in increased expression of RELA mRNA Taurine inhibits the reaction [Malathion results in increased expression of RELA mRNA]
CTD
PMID:28987951 PMID:30673264
NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
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Reln
reelin
increases expression
ISO
Malathion results in increased expression of RELN mRNA
CTD
PMID:37047231
NCBI chr 4:12,736,177...13,162,956
Ensembl chr 4:12,736,130...13,162,211
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Rfc3
replication factor C subunit 3
decreases expression
ISO
Malathion results in decreased expression of RFC3 mRNA
CTD
PMID:16079077
NCBI chr12:1,000,987...1,011,778
Ensembl chr12:1,000,994...1,011,778
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Rft1
RFT1 homolog
decreases expression
ISO
Malathion results in decreased expression of RFT1 mRNA
CTD
PMID:37047231
NCBI chr16:5,827,063...5,861,120
Ensembl chr16:5,827,088...5,861,120
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Rhoa
ras homolog family member A
decreases activity
ISO
Malathion results in decreased activity of RHOA protein
CTD
PMID:37270087
NCBI chr 8:108,991,926...109,025,746
Ensembl chr 8:108,991,954...109,025,746
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Rhox13
Rhox homeobox family member 13
increases expression
ISO
Malathion results in increased expression of RHOXF1 mRNA
CTD
PMID:37047231
NCBI chr X:116,911,226...116,917,758
Ensembl chr X:116,911,329...116,917,644
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Rimbp2
RIMS binding protein 2
decreases expression
ISO
Malathion results in decreased expression of RIMBP2 mRNA
CTD
PMID:37047231
NCBI chr12:27,747,615...27,946,256
Ensembl chr12:27,747,980...27,956,763
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Rnase6
ribonuclease A family member 6
increases expression
EXP
Malathion results in increased expression of RNASE6 mRNA
CTD
PMID:19784758
NCBI chr15:24,354,305...24,357,289
Ensembl chr15:24,354,303...24,357,328
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Rnf170
ring finger protein 170
increases expression
ISO
Malathion results in increased expression of RNF170 mRNA
CTD
PMID:37047231
NCBI chr16:65,928,886...65,954,092
Ensembl chr16:65,928,895...65,954,083
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Rnf183
ring finger protein 183
increases expression
ISO
Malathion results in increased expression of RNF183 mRNA
CTD
PMID:37047231
NCBI chr 5:75,877,111...75,886,253
Ensembl chr 5:75,876,003...75,886,191
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Robo4
roundabout guidance receptor 4
decreases expression
ISO
Malathion results in decreased expression of ROBO4 mRNA
CTD
PMID:37047231
NCBI chr 8:37,119,953...37,133,887
Ensembl chr 8:37,119,988...37,132,519
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Rph3a
rabphilin 3A
decreases expression
ISO
Malathion results in decreased expression of RPH3A mRNA
CTD
PMID:37047231
NCBI chr12:35,542,389...35,618,901
Ensembl chr12:35,542,728...35,617,592
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Rrad
RRAD, Ras related glycolysis inhibitor and calcium channel regulator
increases expression
ISO
Malathion results in increased expression of RRAD mRNA
CTD
PMID:37047231
NCBI chr19:354,184...357,424
Ensembl chr19:354,198...357,417
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Rs1
retinoschisin 1
increases expression
ISO
Malathion results in increased expression of RS1 mRNA
CTD
PMID:37047231
NCBI chr X:33,962,440...33,992,203
Ensembl chr X:33,963,657...33,992,115
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Rsad2
radical S-adenosyl methionine domain containing 2
increases expression
ISO
Malathion results in increased expression of RSAD2 mRNA
CTD
PMID:37047231
NCBI chr 6:43,046,514...43,059,737
Ensembl chr 6:43,047,658...43,059,699
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Rspo2
R-spondin 2
decreases expression
ISO
Malathion results in decreased expression of RSPO2 mRNA
CTD
PMID:37047231
NCBI chr 7:74,096,378...74,239,398
Ensembl chr 7:74,103,090...74,238,933
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RT1-A2
RT1 class Ia, locus A2
decreases expression
ISO
Malathion results in decreased expression of HLA-E mRNA
CTD
PMID:32069766
NCBI chr20:4,870,939...4,910,183
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RT1-CE16
RT1 class I, locus CE16
decreases expression
ISO
Malathion results in decreased expression of HLA-A mRNA
CTD
PMID:32069766
NCBI chr20:3,257,109...3,260,747
Ensembl chr20:3,257,123...3,279,563
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Runx1
RUNX family transcription factor 1
increases expression
ISO
Malathion results in increased expression of RUNX1 mRNA mutant form
CTD
PMID:28624474
NCBI chr11:31,839,880...32,074,427
Ensembl chr11:31,843,764...32,074,542
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S100a1
S100 calcium binding protein A1
decreases expression
ISO
Malathion results in decreased expression of S100A1 mRNA
CTD
PMID:37047231
NCBI chr 2:175,993,922...175,998,765
Ensembl chr 2:175,993,922...175,999,544
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Scg5
secretogranin V
increases expression
ISO
Malathion results in increased expression of SCG5 mRNA
CTD
PMID:37047231
NCBI chr 3:100,544,101...100,588,558
Ensembl chr 3:100,544,099...100,588,463
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Scn9a
sodium voltage-gated channel alpha subunit 9
decreases expression
ISO
Malathion results in decreased expression of SCN9A mRNA
CTD
PMID:37047231
NCBI chr 3:51,145,148...51,293,342
Ensembl chr 3:51,145,146...51,293,516
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Serpinb2
serpin family B member 2
increases expression
ISO
Malathion results in increased expression of SERPINB2 mRNA
CTD
PMID:37047231
NCBI chr13:23,537,312...23,551,823
Ensembl chr13:23,541,400...23,550,408
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Sftpb
surfactant protein B
decreases expression multiple interactions
ISO EXP
Malathion results in decreased expression of SFTPB mRNA Rosmarinic Acid inhibits the reaction [Malathion results in decreased expression of SFTPB protein]; thymoquinone inhibits the reaction [Malathion results in decreased expression of SFTPB mRNA] Malathion results in decreased expression of SFTPB mRNA; Malathion results in decreased expression of SFTPB protein
CTD
PMID:33510276 PMID:34262720 PMID:37047231
NCBI chr 4:104,359,303...104,368,439
Ensembl chr 4:104,359,396...104,368,436
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Sgpp2
sphingosine-1-phosphate phosphatase 2
increases expression
ISO
Malathion results in increased expression of SGPP2 mRNA
CTD
PMID:37047231
NCBI chr 9:79,762,658...79,884,665
Ensembl chr 9:79,763,284...79,880,457
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Shc1
SHC adaptor protein 1
increases expression
ISO
Malathion results in increased expression of SHC1 mRNA
CTD
PMID:32069766
NCBI chr 2:174,837,937...174,849,538
Ensembl chr 2:174,837,930...174,849,536
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Shisa3
shisa family member 3
increases expression
ISO
Malathion results in increased expression of SHISA3 mRNA
CTD
PMID:37047231
NCBI chr14:40,563,672...40,568,244
Ensembl chr14:40,563,673...40,568,244
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Shisa9
shisa family member 9
increases expression
ISO
Malathion results in increased expression of SHISA9 mRNA
CTD
PMID:37047231
NCBI chr10:3,335,616...3,629,334
Ensembl chr10:3,337,979...3,627,773
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Shtn1
shootin 1
decreases expression
ISO
Malathion results in decreased expression of SHTN1 mRNA
CTD
PMID:37047231
NCBI chr 1:258,121,966...258,225,861
Ensembl chr 1:258,121,968...258,228,265
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Slc14a1
solute carrier family 14 member 1 (Kidd blood group)
decreases expression
ISO
Malathion results in decreased expression of SLC14A1 mRNA
CTD
PMID:37047231
NCBI chr18:71,565,453...71,608,807
Ensembl chr18:71,565,454...71,595,146
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Slc22a2
solute carrier family 22 member 2
multiple interactions
ISO
Malathion inhibits the reaction [SLC22A2 protein results in increased uptake of Tetraethylammonium]
CTD
PMID:23770354
NCBI chr 1:48,121,061...48,163,268
Ensembl chr 1:48,121,061...48,163,268
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Slc22a6
solute carrier family 22 member 6
multiple interactions
ISO
Malathion inhibits the reaction [SLC22A6 protein results in increased uptake of p-Aminohippuric Acid]
CTD
PMID:21561794
NCBI chr 1:205,522,579...205,531,179
Ensembl chr 1:205,522,729...205,531,173
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Slc4a5
solute carrier family 4 member 5
decreases expression
ISO
Malathion results in decreased expression of SLC4A5 mRNA
CTD
PMID:37047231
NCBI chr 4:115,710,101...115,810,330
Ensembl chr 4:115,725,592...115,810,323
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Slco4a1
solute carrier organic anion transporter family, member 4a1
increases expression
ISO
Malathion results in increased expression of SLCO4A1 mRNA
CTD
PMID:37047231
NCBI chr 3:167,559,177...167,578,307
Ensembl chr 3:167,559,316...167,578,305
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Smim32
small integral membrane protein 32
decreases expression
ISO
Malathion results in decreased expression of SMIM32 mRNA
CTD
PMID:37047231
NCBI chr17:7,853,492...7,857,235
G
Snca
synuclein alpha
increases expression multiple interactions
EXP
Malathion results in increased expression of SNCA mRNA; Malathion results in increased expression of SNCA protein crocin inhibits the reaction [Malathion results in increased expression of SNCA mRNA]; crocin inhibits the reaction [Malathion results in increased expression of SNCA protein]; Levodopa inhibits the reaction [Malathion results in increased expression of SNCA mRNA]; Levodopa inhibits the reaction [Malathion results in increased expression of SNCA protein]
CTD
PMID:35274200
NCBI chr 4:89,696,420...89,797,240
Ensembl chr 4:89,696,420...89,796,262
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Sntg1
syntrophin, gamma 1
decreases expression
ISO
Malathion results in decreased expression of SNTG1 mRNA
CTD
PMID:37047231
NCBI chr 5:9,980,550...10,794,666
Ensembl chr 5:9,981,115...10,791,181
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Socs3
suppressor of cytokine signaling 3
decreases expression
ISO
Malathion results in decreased expression of SOCS3 mRNA
CTD
PMID:32069766
NCBI chr10:103,193,909...103,197,322
Ensembl chr10:103,193,537...103,197,787
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Sod1
superoxide dismutase 1
increases activity multiple interactions decreases expression
EXP ISO
Malathion results in increased activity of SOD1 protein alpha-Tocopherol inhibits the reaction [Malathion results in increased activity of SOD1 protein] lavender oil inhibits the reaction [Malathion results in decreased expression of SOD1 protein]
CTD
PMID:20194575 PMID:30409133
NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
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Sod2
superoxide dismutase 2
multiple interactions decreases expression
EXP ISO
alpha-Tocopherol inhibits the reaction [Malathion results in increased activity of SOD2 protein]; Malathion results in increased expression of and results in increased activity of SOD2 protein Malathion results in decreased expression of SOD2 protein lavender oil inhibits the reaction [Malathion results in decreased expression of SOD2 protein]
CTD
PMID:20194575 PMID:30409133
NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
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Spata17
spermatogenesis associated 17
decreases expression
ISO
Malathion results in decreased expression of SPATA17 mRNA
CTD
PMID:37047231
NCBI chr13:98,605,986...98,784,855
Ensembl chr13:98,605,986...98,784,929
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Spdya
speedy/RINGO cell cycle regulator family member A
increases expression
ISO
Malathion results in increased expression of SPDYA mRNA
CTD
PMID:37047231
NCBI chr 6:23,905,574...23,954,926
Ensembl chr 6:23,910,223...23,954,850
G
Spink13
serine peptidase inhibitor Kazal type 13
decreases expression
ISO
Malathion results in decreased expression of SPINK13 mRNA
CTD
PMID:37047231
NCBI chr18:56,064,839...56,206,257
Ensembl chr18:56,064,839...56,206,257
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Spink4
serine peptidase inhibitor, Kazal type 4
decreases expression
ISO
Malathion results in decreased expression of SPINK4 mRNA
CTD
PMID:37047231
NCBI chr 5:56,043,936...56,064,841
Ensembl chr 5:55,981,624...56,064,795
G
Srsf5
serine and arginine rich splicing factor 5
decreases expression
EXP
Malathion results in decreased expression of SRSF5 mRNA
CTD
PMID:19784758
NCBI chr 6:100,605,165...100,610,192
Ensembl chr 6:100,605,456...100,610,177
G
Sspo
SCO-spondin
decreases expression
ISO
Malathion results in decreased expression of SSPOP mRNA
CTD
PMID:37047231
NCBI chr 4:77,394,915...77,450,526
Ensembl chr 4:77,397,059...77,450,412
G
Sst
somatostatin
decreases expression
ISO
Malathion results in decreased expression of SST mRNA
CTD
PMID:37047231
NCBI chr11:76,956,896...76,958,173
Ensembl chr11:76,956,896...76,958,173
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Sstr2
somatostatin receptor 2
increases expression
ISO
Malathion results in increased expression of SSTR2 mRNA
CTD
PMID:37047231
NCBI chr10:98,664,204...98,671,370
Ensembl chr10:98,664,216...98,674,351
G
St6gal2
ST6 beta-galactoside alpha-2,6-sialyltransferase 2
increases expression
ISO
Malathion results in increased expression of ST6GAL2 mRNA
CTD
PMID:37047231
NCBI chr 9:9,181,744...9,274,161
Ensembl chr 9:9,182,399...9,269,697
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St8sia1
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
increases expression
EXP
Malathion results in increased expression of ST8SIA1 mRNA
CTD
PMID:19784758
NCBI chr 4:175,782,989...175,921,338
Ensembl chr 4:175,789,947...175,920,708
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St8sia4
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
increases expression
ISO
Malathion results in increased expression of ST8SIA4 mRNA
CTD
PMID:37047231
NCBI chr 9:95,990,131...96,084,661
Ensembl chr 9:95,993,503...96,084,653
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Star
steroidogenic acute regulatory protein
decreases expression multiple interactions
ISO
Malathion results in decreased expression of STAR mRNA lavender oil inhibits the reaction [Malathion results in decreased expression of STAR mRNA]
CTD
PMID:30409133
NCBI chr16:66,267,094...66,274,368
Ensembl chr16:66,264,807...66,271,672
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Stat3
signal transducer and activator of transcription 3
decreases phosphorylation
EXP
Malathion results in decreased phosphorylation of STAT3 protein
CTD
PMID:34778934
NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057
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Stat5b
signal transducer and activator of transcription 5B
decreases activity
ISO
Malathion results in decreased activity of STAT5B protein
CTD
PMID:30114225
NCBI chr10:85,704,841...85,775,856
Ensembl chr10:85,705,670...85,775,668
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Stk36
serine/threonine kinase 36
decreases expression
ISO
Malathion results in decreased expression of STK36 mRNA
CTD
PMID:37047231
NCBI chr 9:76,176,922...76,204,423
Ensembl chr 9:76,176,920...76,204,422
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Stra6
signaling receptor and transporter of retinol STRA6
decreases expression
ISO
Malathion results in decreased expression of STRA6 mRNA
CTD
PMID:37047231
NCBI chr 8:58,548,899...58,568,861
Ensembl chr 8:58,549,736...58,568,860
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Tcf7l1
transcription factor 7 like 1
increases expression
ISO
Malathion results in increased expression of TCF7L1 mRNA
CTD
PMID:37047231
NCBI chr 4:104,680,734...104,846,086
Ensembl chr 4:104,680,739...104,845,287
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Tchhl1
trichohyalin-like 1
decreases expression
ISO
Malathion results in decreased expression of TCHHL1 mRNA
CTD
PMID:37047231
NCBI chr 2:179,134,941...179,138,467
Ensembl chr 2:179,135,796...179,138,202
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Tdrd1
tudor domain containing 1
increases expression
ISO
Malathion results in increased expression of TDRD1 mRNA
CTD
PMID:37047231
NCBI chr 1:255,871,939...255,919,222
Ensembl chr 1:255,875,887...255,915,871
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Tdrd6
tudor domain containing 6
increases expression
ISO
Malathion results in increased expression of TDRD6 mRNA
CTD
PMID:37047231
NCBI chr 9:17,344,033...17,359,348
Ensembl chr 9:17,344,026...17,359,344
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Tdrp
testis development related protein
decreases expression
ISO
Malathion results in decreased expression of TDRP mRNA
CTD
PMID:37047231
NCBI chr16:75,624,047...75,652,635
Ensembl chr16:75,624,907...75,652,420
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Tek
TEK receptor tyrosine kinase
increases expression
ISO
Malathion results in increased expression of TEK mRNA
CTD
PMID:32069766
NCBI chr 5:109,607,077...109,733,805
Ensembl chr 5:109,607,077...109,733,804
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Tet1
tet methylcytosine dioxygenase 1
affects expression
EXP
Malathion affects the expression of TET1 mRNA
CTD
PMID:36370973
NCBI chr20:25,761,042...25,840,926
Ensembl chr20:25,768,120...25,833,052
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Tet2
tet methylcytosine dioxygenase 2
decreases expression
EXP
Malathion results in decreased expression of TET2 mRNA
CTD
PMID:36370973
NCBI chr 2:221,988,645...222,072,813
Ensembl chr 2:221,988,645...222,072,534
G
Tet3
tet methylcytosine dioxygenase 3
affects expression
EXP
Malathion affects the expression of TET3 mRNA
CTD
PMID:36370973
NCBI chr 4:115,867,412...115,964,433
Ensembl chr 4:115,871,265...115,964,193
G
Tfpi2
tissue factor pathway inhibitor 2
increases expression
ISO
Malathion results in increased expression of TFPI2 mRNA
CTD
PMID:37047231
NCBI chr 4:31,981,786...31,986,707
Ensembl chr 4:31,982,178...31,986,600
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Tfrc
transferrin receptor
increases expression
ISO
Malathion results in increased expression of TFRC mRNA
CTD
PMID:32069766
NCBI chr11:68,163,413...68,185,257
Ensembl chr11:68,163,413...68,185,257
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Tg
thyroglobulin
decreases expression
EXP
Malathion results in decreased expression of TG mRNA; Malathion results in decreased expression of TG protein
CTD
PMID:29143548
NCBI chr 7:98,418,293...98,603,210
Ensembl chr 7:98,418,293...98,603,210
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Tifab
TIFA inhibitor
decreases expression
ISO
Malathion results in decreased expression of TIFAB mRNA
CTD
PMID:37047231
NCBI chr17:8,433,406...8,436,541
Ensembl chr17:8,431,635...8,436,592
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Timp3
TIMP metallopeptidase inhibitor 3
decreases expression
EXP
Malathion results in decreased expression of TIMP3 mRNA
CTD
PMID:19784758
NCBI chr 7:17,520,827...17,571,850
Ensembl chr 7:17,521,919...17,571,839
G
Tjp1
tight junction protein 1
multiple interactions decreases expression
EXP
[Malathion co-treated with Lead] results in decreased expression of TJP1 protein Malathion results in decreased expression of TJP1 protein
CTD
PMID:20970449
NCBI chr 1:118,849,838...119,094,492
Ensembl chr 1:118,849,838...119,094,432
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Tjp2
tight junction protein 2
multiple interactions decreases expression
EXP
[Malathion co-treated with Lead] results in decreased expression of TJP2 protein Malathion results in decreased expression of TJP2 protein
CTD
PMID:20970449
NCBI chr 1:221,709,745...221,838,291
Ensembl chr 1:221,709,745...221,838,295
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Tlr4
toll-like receptor 4
multiple interactions increases expression
ISO
Plant Extracts inhibits the reaction [Malathion results in increased expression of TLR4 protein]; Polyphenols inhibits the reaction [Malathion results in increased expression of TLR4 protein]
CTD
PMID:32120800
NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628
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Tlr8
toll-like receptor 8
increases expression
ISO
Malathion results in increased expression of TLR8 mRNA
CTD
PMID:32069766
NCBI chr X:27,091,780...27,116,092
Ensembl chr X:27,091,778...27,116,549
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Tmem114
transmembrane protein 114
decreases expression
ISO
Malathion results in decreased expression of TMEM114 mRNA
CTD
PMID:37047231
NCBI chr10:7,168,998...7,185,251
Ensembl chr10:7,169,746...7,185,251
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Tmem158
transmembrane protein 158
increases expression
ISO
Malathion results in increased expression of TMEM158 mRNA
CTD
PMID:37047231
NCBI chr 8:122,913,675...122,914,673
Ensembl chr 8:122,913,675...122,914,673
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Tmem241
transmembrane protein 241
decreases expression
ISO
Malathion results in decreased expression of TMEM241 mRNA
CTD
PMID:37047231
NCBI chr18:3,168,072...3,318,340
Ensembl chr18:3,168,067...3,318,293
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Tmem65
transmembrane protein 65
increases expression
ISO
Malathion results in increased expression of TMEM65 mRNA
CTD
PMID:37047231
NCBI chr 7:90,336,997...90,378,930
Ensembl chr 7:90,274,142...90,379,474
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Tnf
tumor necrosis factor
increases expression multiple interactions
EXP ISO
Malathion results in increased expression of TNF mRNA Taurine inhibits the reaction [Malathion results in increased expression of TNF mRNA]
CTD
PMID:28987951 PMID:37047231
NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
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Tnfaip6
TNF alpha induced protein 6
increases expression
ISO
Malathion results in increased expression of TNFAIP6 mRNA
CTD
PMID:37047231
NCBI chr 3:36,502,250...36,521,652
Ensembl chr 3:36,502,188...36,521,649
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Tnfaip8l3
TNF alpha induced protein 8 like 3
decreases expression
ISO
Malathion results in decreased expression of TNFAIP8L3 mRNA
CTD
PMID:37047231
NCBI chr 8:54,413,503...54,455,512
Ensembl chr 8:54,414,457...54,500,079
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Tnfsf15
TNF superfamily member 15
affects expression
ISO
Malathion affects the expression of TNFSF15 mRNA
CTD
PMID:37047231
NCBI chr 5:77,134,885...77,156,171
Ensembl chr 5:77,139,878...77,156,228
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Tnip3
TNFAIP3 interacting protein 3
increases expression
ISO
Malathion results in increased expression of TNIP3 mRNA
CTD
PMID:37047231
NCBI chr 4:94,867,258...94,908,780
Ensembl chr 4:94,811,097...94,907,605
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Tp53
tumor protein p53
multiple interactions increases expression
ISO EXP
Atropine inhibits the reaction [Malathion results in increased expression of TP53 protein] Malathion results in increased expression of TP53 mRNA; Malathion results in increased expression of TP53 protein Malathion results in increased expression of TRP53 protein [Vitamin E co-treated with Selenium] inhibits the reaction [Malathion results in increased expression of TP53 mRNA] Plant Extracts inhibits the reaction [Malathion results in increased expression of TRP53 protein]; Polyphenols inhibits the reaction [Malathion results in increased expression of TRP53 protein]
CTD
PMID:12505448 PMID:12762645 PMID:18204794 PMID:19787260 PMID:21628957 PMID:32120800 More...
NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
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Tp53i3
tumor protein p53 inducible protein 3
increases expression multiple interactions
ISO
Malathion results in increased expression of TP53I3 mRNA [Malathion co-treated with Estrogens] results in increased expression of TP53I3 mRNA
CTD
PMID:18204794
NCBI chr 6:27,818,327...27,825,753
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Tpd52l3
TPD52 like 3
decreases expression
ISO
Malathion results in decreased expression of TPD52L3 mRNA
CTD
PMID:37047231
NCBI chr 1:227,781,173...227,785,040
Ensembl chr 1:227,773,724...227,784,467
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Tpr
translocated promoter region, nuclear basket protein
increases expression
ISO
Malathion results in increased expression of TPR mRNA
CTD
PMID:32069766
NCBI chr13:62,424,312...62,487,502
Ensembl chr13:62,424,312...62,487,496
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Tram1l1
translocation associated membrane protein 1-like 1
increases expression
ISO
Malathion results in increased expression of TRAM1L1 mRNA
CTD
PMID:37047231
NCBI chr 2:212,511,130...212,513,311
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Trim35
tripartite motif-containing 35
decreases expression
ISO
Malathion results in decreased expression of TRIM35 mRNA
CTD
PMID:32069766
NCBI chr15:40,493,697...40,510,246
Ensembl chr15:40,493,755...40,510,240
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Trpc1
transient receptor potential cation channel, subfamily C, member 1
increases expression
EXP
Malathion results in increased expression of TRPC1 mRNA; Malathion results in increased expression of TRPC1 protein
CTD
PMID:22674931
NCBI chr 8:96,263,322...96,314,220
Ensembl chr 8:96,263,329...96,314,276
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Trpc4
transient receptor potential cation channel, subfamily C, member 4
increases expression decreases expression
EXP ISO
Malathion results in increased expression of TRPC4 mRNA; Malathion results in increased expression of TRPC4 protein Malathion results in decreased expression of TRPC4 mRNA
CTD
PMID:22674931 PMID:37047231
NCBI chr 2:138,307,676...138,476,856
Ensembl chr 2:138,308,084...138,476,768
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Trpc5os
TRPC5 opposite strand
increases expression
ISO
Malathion results in increased expression of TRPC5OS mRNA
CTD
PMID:37047231
NCBI chr X:108,025,172...108,044,201
Ensembl chr X:108,024,924...108,046,581
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Tshr
thyroid stimulating hormone receptor
decreases expression
EXP
Malathion results in decreased expression of TSHR protein
CTD
PMID:29143548
NCBI chr 6:110,341,585...110,475,297
Ensembl chr 6:110,341,581...110,474,538
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Ttc9
tetratricopeptide repeat domain 9
decreases expression
ISO
Malathion results in decreased expression of TTC9 mRNA
CTD
PMID:37047231
NCBI chr 6:101,333,274...101,368,110
Ensembl chr 6:101,333,141...101,368,110
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Tusc2
tumor suppressor 2, mitochondrial calcium regulator
decreases expression
ISO
Malathion results in decreased expression of TUSC2 mRNA
CTD
PMID:32069766
NCBI chr 8:108,236,838...108,240,056
Ensembl chr 8:108,236,838...108,240,056
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Twist1
twist family bHLH transcription factor 1
increases expression
ISO
Malathion results in increased expression of TWIST1 mRNA
CTD
PMID:32069766
NCBI chr 6:50,674,910...50,676,904
Ensembl chr 6:50,674,678...50,677,653
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Txnrd3
thioredoxin reductase 3
decreases expression
ISO
Malathion results in decreased expression of TXNRD3 mRNA
CTD
PMID:37047231
NCBI chr 4:122,072,548...122,112,493
Ensembl chr 4:122,072,548...122,112,491
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Tyms
thymidylate synthetase
decreases expression
ISO
Malathion results in decreased expression of TYMS mRNA
CTD
PMID:16079077
NCBI chr 9:113,313,454...113,329,551
Ensembl chr 9:113,313,452...113,329,536
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Ubd
ubiquitin D
increases expression
ISO
Malathion results in increased expression of UBD mRNA
CTD
PMID:37047231
NCBI chr20:1,385,487...1,387,438
Ensembl chr20:1,385,864...1,408,639 Ensembl chr20:1,385,864...1,408,639
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Umodl1
uromodulin-like 1
increases expression
ISO
Malathion results in increased expression of UMODL1 mRNA
CTD
PMID:37047231
NCBI chr20:9,027,751...9,087,133
Ensembl chr20:9,025,724...9,087,146
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Usp2
ubiquitin specific peptidase 2
increases expression
ISO
Malathion results in increased expression of USP2 mRNA
CTD
PMID:37047231
NCBI chr 8:44,411,457...44,439,668
Ensembl chr 8:44,411,607...44,438,331
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Usp27x
ubiquitin specific peptidase 27, X-linked
increases expression
ISO
Malathion results in increased expression of USP27X mRNA
CTD
PMID:37047231
NCBI chr X:15,123,620...15,126,855
Ensembl chr X:15,124,596...15,125,912
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Vhl
von Hippel-Lindau tumor suppressor
decreases expression
ISO
Malathion results in decreased expression of VHL mRNA
CTD
PMID:32069766
NCBI chr 4:146,772,483...146,779,376
Ensembl chr 4:146,772,468...146,779,377
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Vpreb3
V-set pre-B cell surrogate light chain 3
increases expression
ISO
Malathion results in increased expression of VPREB3 mRNA
CTD
PMID:32069766
NCBI chr20:12,717,421...12,718,785
Ensembl chr20:12,716,779...12,719,520
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Wbp2nl
WBP2 N-terminal like
decreases expression
ISO
Malathion results in decreased expression of WBP2NL mRNA
CTD
PMID:37047231
NCBI chr 7:113,814,793...113,831,974
Ensembl chr 7:113,814,992...113,831,333
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Wfdc6a
WAP four-disulfide core domain 6A
decreases expression
ISO
Malathion results in decreased expression of WFDC6 mRNA
CTD
PMID:37047231
NCBI chr 3:153,305,336...153,309,144
Ensembl chr 3:153,305,336...153,309,144
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Wipf3
WAS/WASL interacting protein family, member 3
decreases expression
ISO
Malathion results in decreased expression of WIPF3 mRNA
CTD
PMID:37047231
NCBI chr 4:83,550,075...83,629,929
Ensembl chr 4:83,550,468...83,629,386
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Wt1
WT1 transcription factor
increases expression
ISO
Malathion results in increased expression of WT1 mRNA
CTD
PMID:32069766
NCBI chr 3:91,566,540...91,613,653
Ensembl chr 3:91,567,001...91,613,643
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Xkr4
XK related 4
decreases expression
ISO
Malathion results in decreased expression of XKR4 mRNA
CTD
PMID:37047231
NCBI chr 5:15,896,818...16,297,733
Ensembl chr 5:15,895,863...16,282,962
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Zfp42
zinc finger protein 42
decreases expression
ISO
Malathion results in decreased expression of ZFP42 mRNA
CTD
PMID:37047231
NCBI chr16:48,836,463...48,845,443
Ensembl chr16:48,836,648...48,845,401 Ensembl chr 4:48,836,648...48,845,401
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Zfpm2
zinc finger protein, multitype 2
increases expression
ISO
Malathion results in increased expression of ZFPM2 mRNA
CTD
PMID:37047231
NCBI chr 7:71,678,658...72,116,209
Ensembl chr 7:71,678,880...72,116,205
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Zscan5b
zinc finger and SCAN domain containing 5B
decreases expression
ISO
Malathion results in decreased expression of ZSCAN5B mRNA
CTD
PMID:37047231
NCBI chr 1:67,666,684...67,674,238
Ensembl chr 1:67,666,691...67,674,238
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