Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:linuron
go back to main search page
Accession:CHEBI:6482 term browser browse the term
Definition:A member of the class of phenylureas that is N-methyl urea substituted by a methoxy group at position 1 and a 3,4-dichlorophenyl group at position 3.
Synonyms:related_synonym: 1-Methoxy-1-methyl-3-(3,4-dichlorophenyl)urea;   3-(3,4-dichlorophenyl)-1-methoxy-1-methylurea;   Formula=C9H10Cl2N2O2;   InChI=1S/C9H10Cl2N2O2/c1-13(15-2)9(14)12-6-3-4-7(10)8(11)5-6/h3-5H,1-2H3,(H,12,14);   InChIKey=XKJMBINCVNINCA-UHFFFAOYSA-N;   N'-(3,4-dichlorophenyl)-N-methoxy-N-methyl Urea;   SMILES=CON(C)C(=O)Nc1ccc(Cl)c(Cl)c1
 xref: CAS:330-55-2;   KEGG:C11007
 xref_mesh: MESH:D008044
 xref: PMID:23586778;   PMID:24410802;   PMID:25238184;   PPDB:419;   Pesticides:linuron;   Reaxys:2128725


show annotations for term's descendants           Sort by:
linuron term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actn1 actinin, alpha 1 multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of ACTN1 mRNA CTD PMID:25607892 NCBI chr 6:98,998,553...99,093,334
Ensembl chr 6:98,998,556...99,093,251 		JBrowse link
G Ahr aryl hydrocarbon receptor multiple interactions
increases expression		 ISO Linuron binds to and results in increased activity of AHR protein; SIGMAR1 gene promotes the reaction [Linuron results in increased expression of AHR mRNA]; XBP1 gene promotes the reaction [Linuron results in increased expression of AHR mRNA] CTD PMID:18835618 PMID:30661753 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568 		JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 increases expression EXP Linuron results in increased expression of APAF1 mRNA CTD PMID:28705778 NCBI chr 7:25,494,143...25,579,540
Ensembl chr 7:25,494,609...25,579,540 		JBrowse link
G Ar androgen receptor multiple interactions
decreases activity
increases expression
decreases expression
affects binding
affects activity		 ISO
EXP		 Dihydrotestosterone inhibits the reaction [Linuron results in increased activity of AR protein]; Linuron binds to and results in decreased activity of AR protein; Linuron inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; Linuron inhibits the reaction [Dihydrotestosterone binds to and results in increased activity of AR protein]; Linuron inhibits the reaction [Dihydrotestosterone results in increased activity of AR protein]; Linuron inhibits the reaction [Dihydrotestosterone results in increased expression of AR mRNA]; Linuron inhibits the reaction [Metribolone binds to AR protein]; Linuron inhibits the reaction [Metribolone results in increased activity of AR protein]; Linuron inhibits the reaction [Stanozolol binds to and results in increased activity of AR protein]; Linuron inhibits the reaction [Testosterone results in increased activity of AR protein]; methoxyacetic acid inhibits the reaction [Linuron inhibits the reaction [Testosterone results in increased activity of AR protein]]
Linuron results in decreased activity of AR protein
Linuron results in increased expression of AR mRNA
Linuron binds to and results in decreased activity of AR protein; Linuron inhibits the reaction [Dihydrotestosterone binds to and results in increased activity of AR protein]; Linuron inhibits the reaction [Metribolone binds to AR protein]
Linuron results in decreased expression of AR mRNA
Linuron binds to AR protein
Linuron affects the activity of AR protein		 CTD PMID:10910998 PMID:10964759 PMID:11861974 PMID:12730624 PMID:14565775 More... NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925 		JBrowse link
G Arg1 arginase 1 increases expression
multiple interactions		 ISO Linuron results in increased expression of ARG1 mRNA
SIGMAR1 gene mutant form inhibits the reaction [Linuron results in increased expression of ARG1 mRNA]; XBP1 gene mutant form inhibits the reaction [Linuron results in increased expression of ARG1 mRNA]		 CTD PMID:30661753 NCBI chr 1:20,475,878...20,488,422
Ensembl chr 1:20,475,968...20,488,422 		JBrowse link
G Arnt aryl hydrocarbon receptor nuclear translocator multiple interactions ISO XBP1 gene promotes the reaction [Linuron results in increased expression of ARNT mRNA] CTD PMID:30661753 NCBI chr 2:182,997,731...183,056,584
Ensembl chr 2:182,997,736...183,056,580 		JBrowse link
G Avp arginine vasopressin multiple interactions EXP [Plasticizers co-treated with Fungicides, Industrial co-treated with Linuron co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with Dichlorodiphenyl Dichloroethylene co-treated with butylparaben co-treated with Acetaminophen] results in decreased expression of AVP mRNA CTD PMID:34383603 NCBI chr 3:117,793,447...117,805,091
Ensembl chr 3:117,793,457...117,795,425 		JBrowse link
G Bace1 beta-secretase 1 multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of BACE1 mRNA CTD PMID:25607892 NCBI chr 8:46,142,060...46,166,268
Ensembl chr 8:46,142,116...46,165,876 		JBrowse link
G Bace2 beta-secretase 2 multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of BACE2 mRNA CTD PMID:25607892 NCBI chr11:36,707,447...36,789,550
Ensembl chr11:36,707,458...36,789,546 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression EXP Linuron results in increased expression of BAX mRNA CTD PMID:36410587 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bdnf brain-derived neurotrophic factor multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of BDNF mRNA CTD PMID:25607892 NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615 		JBrowse link
G Becn1 beclin 1 increases expression EXP Linuron results in increased expression of BECN1 mRNA CTD PMID:28705778 NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742 		JBrowse link
G Bmp4 bone morphogenetic protein 4 decreases expression EXP Linuron results in decreased expression of BMP4 mRNA CTD PMID:12730624 NCBI chr15:19,618,538...19,633,494
Ensembl chr15:19,618,542...19,623,306 		JBrowse link
G Bmpr1b bone morphogenetic protein receptor type 1B decreases expression EXP Linuron results in decreased expression of BMPR1B mRNA CTD PMID:12730624 NCBI chr 2:230,538,252...230,871,077
Ensembl chr 2:230,541,558...230,871,368 		JBrowse link
G Bsn bassoon (presynaptic cytomatrix protein) multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of BSN mRNA CTD PMID:25607892 NCBI chr 8:108,784,849...108,875,819
Ensembl chr 8:108,788,542...108,875,819 		JBrowse link
G Cacna1a calcium voltage-gated channel subunit alpha1 A multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of CACNA1A mRNA CTD PMID:25607892 NCBI chr19:23,520,741...23,819,971
Ensembl chr19:23,520,741...23,823,225 		JBrowse link
G Cacna1b calcium voltage-gated channel subunit alpha1 B multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of CACNA1B mRNA CTD PMID:25607892 NCBI chr 3:7,380,892...7,546,104
Ensembl chr 3:7,380,922...7,546,091 		JBrowse link
G Cacna1c calcium voltage-gated channel subunit alpha1 C multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of CACNA1C mRNA CTD PMID:25607892 NCBI chr 4:151,764,138...152,379,454
Ensembl chr 4:151,764,138...152,379,648 		JBrowse link
G Cacna1d calcium voltage-gated channel subunit alpha1 D multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of CACNA1D mRNA CTD PMID:25607892 NCBI chr16:5,227,157...5,521,163
Ensembl chr16:5,228,306...5,668,215 		JBrowse link
G Cacna1g calcium voltage-gated channel subunit alpha1 G multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of CACNA1G mRNA CTD PMID:25607892 NCBI chr10:79,354,998...79,422,960
Ensembl chr10:79,355,008...79,422,752 		JBrowse link
G Cacna1i calcium voltage-gated channel subunit alpha1 I multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of CACNA1I mRNA CTD PMID:25607892 NCBI chr 7:111,835,996...111,947,418
Ensembl chr 7:111,836,012...111,944,688 		JBrowse link
G Cacna2d3 calcium voltage-gated channel auxiliary subunit alpha2delta 3 multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] affects the expression of CACNA2D3 mRNA CTD PMID:25607892 NCBI chr16:4,098,439...4,912,498
Ensembl chr16:4,098,445...4,912,351 		JBrowse link
G Cacnb1 calcium voltage-gated channel auxiliary subunit beta 1 multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of CACNB1 mRNA CTD PMID:25607892 NCBI chr10:82,998,182...83,018,838
Ensembl chr10:82,998,182...83,018,694 		JBrowse link
G Cacnb3 calcium voltage-gated channel auxiliary subunit beta 3 multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of CACNB3 mRNA CTD PMID:25607892 NCBI chr 7:129,784,799...129,797,074
Ensembl chr 7:129,783,674...129,797,074 		JBrowse link
G Cacng2 calcium voltage-gated channel auxiliary subunit gamma 2 multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of CACNG2 mRNA CTD PMID:25607892 NCBI chr 7:109,572,838...109,698,516
Ensembl chr 7:109,574,459...109,697,227 		JBrowse link
G Cacng6 calcium voltage-gated channel auxiliary subunit gamma 6 multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of CACNG6 mRNA CTD PMID:25607892 NCBI chr 1:65,732,910...65,747,377
Ensembl chr 1:65,732,632...65,747,341 		JBrowse link
G Cacng7 calcium voltage-gated channel auxiliary subunit gamma 7 multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of CACNG7 mRNA CTD PMID:25607892 NCBI chr 1:65,800,059...65,831,246
Ensembl chr 1:65,800,355...65,831,006 		JBrowse link
G Cadm1 cell adhesion molecule 1 multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of CADM1 mRNA CTD PMID:25607892 NCBI chr 8:47,847,836...48,178,703
Ensembl chr 8:47,847,325...48,182,833 		JBrowse link
G Camk2b calcium/calmodulin-dependent protein kinase II beta multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of CAMK2B mRNA CTD PMID:25607892 NCBI chr14:80,845,206...80,934,172
Ensembl chr14:80,845,238...80,933,994 		JBrowse link
G Camk2g calcium/calmodulin-dependent protein kinase II gamma multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] affects the expression of CAMK2G mRNA CTD PMID:25607892 NCBI chr15:3,504,017...3,563,050
Ensembl chr15:3,504,085...3,563,050 		JBrowse link
G Cartpt CART prepropeptide multiple interactions EXP [Plasticizers co-treated with Fungicides, Industrial co-treated with Linuron co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with Dichlorodiphenyl Dichloroethylene co-treated with butylparaben co-treated with Acetaminophen] results in increased expression of CARTPT mRNA CTD PMID:34383603 NCBI chr 2:31,255,098...31,257,452
Ensembl chr 2:31,255,098...31,290,713 		JBrowse link
G Casp3 caspase 3 increases expression EXP Linuron results in increased expression of CASP3 mRNA CTD PMID:28705778 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Ccl1 C-C motif chemokine ligand 1 increases expression
multiple interactions		 ISO Linuron results in increased expression of CCL1 mRNA
SIGMAR1 gene mutant form inhibits the reaction [Linuron results in increased expression of CCL1 mRNA]; XBP1 gene mutant form inhibits the reaction [Linuron results in increased expression of CCL1 mRNA]		 CTD PMID:30661753 NCBI chr10:67,128,331...67,131,109
Ensembl chr10:67,128,331...67,131,159 		JBrowse link
G Ccl17 C-C motif chemokine ligand 17 multiple interactions
increases expression		 ISO SIGMAR1 gene mutant form inhibits the reaction [Linuron results in increased expression of CCL17 mRNA] CTD PMID:30661753 NCBI chr19:10,202,128...10,203,903
Ensembl chr19:10,202,128...10,203,819 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 increases expression
multiple interactions		 ISO Linuron results in increased expression of CCL2 mRNA
1-(2-(3,4-dichlorophenyl)ethyl)-4-methylpiperazine inhibits the reaction [Linuron promotes the reaction [[IL1B protein co-treated with TNF protein] results in increased expression of CCL2 mRNA]]; Linuron promotes the reaction [[IL1B protein co-treated with TNF protein] results in increased expression of CCL2 mRNA]; XBP1 gene mutant form inhibits the reaction [Linuron results in increased expression of CCL2 mRNA]		 CTD PMID:30661753 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226 		JBrowse link
G Ccl20 C-C motif chemokine ligand 20 increases expression
multiple interactions		 ISO Linuron results in increased expression of CCL20 mRNA
SIGMAR1 gene mutant form inhibits the reaction [Linuron results in increased expression of CCL20 mRNA]; XBP1 gene mutant form inhibits the reaction [Linuron results in increased expression of CCL20 mRNA]		 CTD PMID:30661753 NCBI chr 9:84,389,031...84,391,629
Ensembl chr 9:84,388,904...84,391,629 		JBrowse link
G Ccl4 C-C motif chemokine ligand 4 increases expression
multiple interactions		 ISO Linuron results in increased expression of CCL4 mRNA
SIGMAR1 gene mutant form inhibits the reaction [Linuron results in increased expression of CCL4 mRNA]		 CTD PMID:30661753 NCBI chr10:68,466,394...68,468,229
Ensembl chr10:68,452,052...68,468,231 		JBrowse link
G Ccr2 C-C motif chemokine receptor 2 multiple interactions
increases expression		 ISO SIGMAR1 gene mutant form inhibits the reaction [Linuron results in increased expression of CCR2 mRNA]; XBP1 gene mutant form inhibits the reaction [Linuron results in increased expression of CCR2 mRNA] CTD PMID:30661753 NCBI chr 8:123,734,465...123,742,483
Ensembl chr 8:123,734,430...123,742,100 		JBrowse link
G Cd44 CD44 molecule multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of CD44 mRNA CTD PMID:25607892 NCBI chr 3:89,155,850...89,244,615
Ensembl chr 3:89,157,058...89,244,620 		JBrowse link
G Cd81 Cd81 molecule multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of CD81 mRNA CTD PMID:25607892 NCBI chr 1:198,235,861...198,251,660
Ensembl chr 1:198,241,484...198,251,660 		JBrowse link
G Cdk2 cyclin dependent kinase 2 decreases expression EXP Linuron results in decreased expression of CDK2 mRNA CTD PMID:28705778 NCBI chr 7:1,129,878...1,137,431
Ensembl chr 7:1,129,811...1,137,403 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression EXP Linuron results in increased expression of CDKN1A mRNA CTD PMID:28705778 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585 		JBrowse link
G Chga chromogranin A multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of CHGA mRNA CTD PMID:25607892 NCBI chr 6:121,696,051...121,707,399
Ensembl chr 6:121,696,051...121,707,398 		JBrowse link
G Cntf ciliary neurotrophic factor multiple interactions
increases expression		 ISO XBP1 gene promotes the reaction [Linuron results in increased expression of CNTF mRNA] CTD PMID:30661753 NCBI chr 1:209,887,854...209,889,877
Ensembl chr 1:209,887,854...209,889,877 		JBrowse link
G Cox7a2 cytochrome c oxidase subunit 7A2 increases expression EXP Linuron results in increased expression of COX7A2 mRNA CTD PMID:28705778 NCBI chr 8:80,716,824...80,720,922
Ensembl chr14:51,301,168...51,301,633
Ensembl chr 8:51,301,168...51,301,633 		JBrowse link
G Crh corticotropin releasing hormone multiple interactions EXP [Plasticizers co-treated with Fungicides, Industrial co-treated with Linuron co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with Dichlorodiphenyl Dichloroethylene co-treated with butylparaben co-treated with Acetaminophen] affects the expression of CRH mRNA CTD PMID:34383603 NCBI chr 2:102,143,055...102,144,919
Ensembl chr 2:102,143,055...102,144,919 		JBrowse link
G Csf2 colony stimulating factor 2 increases expression
multiple interactions		 ISO Linuron results in increased expression of CSF2 mRNA
1-(2-(3,4-dichlorophenyl)ethyl)-4-methylpiperazine inhibits the reaction [Linuron promotes the reaction [[IL1B protein co-treated with TNF protein] results in increased expression of CSF2 mRNA]]; Linuron promotes the reaction [[IL1B protein co-treated with TNF protein] results in increased expression of CSF2 mRNA]; SIGMAR1 gene mutant form inhibits the reaction [Linuron results in increased expression of CSF2 mRNA]; XBP1 gene mutant form inhibits the reaction [Linuron results in increased expression of CSF2 mRNA]		 CTD PMID:30661753 NCBI chr10:38,386,945...38,388,926
Ensembl chr10:38,386,945...38,389,199 		JBrowse link
G Cspg4 chondroitin sulfate proteoglycan 4 multiple interactions
increases expression		 ISO SIGMAR1 gene promotes the reaction [Linuron results in increased expression of CSPG4 mRNA]; XBP1 gene promotes the reaction [Linuron results in increased expression of CSPG4 mRNA] CTD PMID:30661753 NCBI chr 8:57,264,962...57,300,010
Ensembl chr 8:57,264,962...57,300,010 		JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 increases expression
multiple interactions		 ISO Linuron results in increased expression of CXCL10 mRNA
SIGMAR1 gene mutant form inhibits the reaction [Linuron results in increased expression of CXCL10 mRNA]		 CTD PMID:30661753 NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975 		JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 increases expression
multiple interactions		 ISO Linuron results in increased expression of CXCL12 mRNA
XBP1 gene promotes the reaction [Linuron results in increased expression of CXCL12 mRNA]		 CTD PMID:30661753 NCBI chr 4:150,388,326...150,401,173
Ensembl chr 4:150,388,325...150,401,168 		JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 decreases expression EXP Linuron results in decreased expression of CYP11A1 mRNA; Linuron results in decreased expression of CYP11A1 protein CTD PMID:28007637 PMID:28705778 NCBI chr 8:58,422,807...58,434,342
Ensembl chr 8:58,404,669...58,434,338 		JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 decreases expression EXP Linuron results in decreased expression of CYP17A1 mRNA CTD PMID:28007637 PMID:28705778 NCBI chr 1:245,535,462...245,543,148
Ensembl chr 1:245,535,462...245,541,573 		JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of CYP19A1 mRNA CTD PMID:25607892 NCBI chr 8:54,552,978...54,580,375
Ensembl chr 8:54,553,165...54,580,758 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases activity EXP Linuron results in increased activity of CYP1A1 protein CTD PMID:7823289 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 decreases response to substance ISO CYP1A2 protein results in decreased susceptibility to Linuron CTD PMID:29573710 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312 		JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 increases expression
multiple interactions		 ISO Linuron results in increased expression of CYP1B1 mRNA
XBP1 gene promotes the reaction [Linuron results in increased expression of CYP1B1 mRNA]		 CTD PMID:16040568 PMID:30661753 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917 		JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 affects activity EXP Linuron affects the activity of CYP2B1 protein CTD PMID:7823289 NCBI chr 1:81,518,387...81,544,999
Ensembl chr 1:81,518,408...81,542,052 		JBrowse link
G Cyp2b2 cytochrome P450, family 2, subfamily b, polypeptide 2 affects activity EXP Linuron affects the activity of CYP2B2 protein CTD PMID:7823289 NCBI chr 1:81,594,534...81,608,567
Ensembl chr 1:81,594,555...81,608,566 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 multiple interactions ISO [Chlorfenvinphos co-treated with ethion co-treated with Linuron] results in increased expression of CYP3A4 mRNA CTD PMID:25028461 NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008 		JBrowse link
G Dcc DCC netrin 1 receptor multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of DCC mRNA CTD PMID:25607892 NCBI chr18:64,868,987...65,972,783
Ensembl chr18:64,873,898...65,972,740 		JBrowse link
G Ddx4 DEAD-box helicase 4 increases expression EXP Linuron results in increased expression of DDX4 mRNA CTD PMID:36410587 NCBI chr 2:44,227,946...44,282,867
Ensembl chr 2:44,227,946...44,282,723 		JBrowse link
G Dlg1 discs large MAGUK scaffold protein 1 multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of DLG1 mRNA CTD PMID:25607892 NCBI chr11:68,911,883...69,103,230
Ensembl chr11:68,911,883...69,102,689 		JBrowse link
G Dlg4 discs large MAGUK scaffold protein 4 multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] affects the expression of DLG4 mRNA; [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of DLG4 mRNA CTD PMID:25607892 NCBI chr10:54,740,700...54,769,097
Ensembl chr10:54,739,470...54,767,153 		JBrowse link
G Dlgap3 DLG associated protein 3 multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of DLGAP3 mRNA CTD PMID:25607892 NCBI chr 5:139,491,972...139,562,625
Ensembl chr 5:139,492,947...139,562,625 		JBrowse link
G Dlgap4 DLG associated protein 4 multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of DLGAP4 mRNA CTD PMID:25607892 NCBI chr 3:145,124,189...145,271,791
Ensembl chr 3:145,175,479...145,270,490 		JBrowse link
G Dll1 delta like canonical Notch ligand 1 increases expression EXP Linuron results in increased expression of DLL1 mRNA CTD PMID:12730624 NCBI chr 1:56,312,062...56,320,177
Ensembl chr 1:56,312,066...56,320,179 		JBrowse link
G Dnm1 dynamin 1 multiple interactions EXP [Plasticizers co-treated with Fungicides, Industrial co-treated with Linuron co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with Dichlorodiphenyl Dichloroethylene co-treated with butylparaben co-treated with Acetaminophen] results in decreased expression of DNM1 mRNA CTD PMID:34383603 NCBI chr 3:15,604,782...15,648,654
Ensembl chr 3:15,604,784...15,648,538 		JBrowse link
G Doc2a double C2 domain alpha multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of DOC2A mRNA CTD PMID:25607892 NCBI chr 1:181,457,415...181,462,528
Ensembl chr 1:181,458,390...181,462,030 		JBrowse link
G Dpp10 dipeptidyl peptidase like 10 multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of DPP10 mRNA CTD PMID:25607892 NCBI chr13:34,584,420...36,269,292
Ensembl chr13:34,595,868...36,269,292 		JBrowse link
G Dpp6 dipeptidyl peptidase like 6 multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of DPP6 mRNA CTD PMID:25607892 NCBI chr 4:7,589,386...8,508,666
Ensembl chr 4:7,591,009...8,508,532 		JBrowse link
G Dpyd dihydropyrimidine dehydrogenase multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of DPYD mRNA CTD PMID:25607892 NCBI chr 2:206,609,043...207,474,982
Ensembl chr 2:206,609,122...207,474,982 		JBrowse link
G Egf epidermal growth factor multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of EGF mRNA CTD PMID:25607892 NCBI chr 2:218,219,408...218,302,359
Ensembl chr 2:218,219,415...218,302,064 		JBrowse link
G Egfr epidermal growth factor receptor decreases expression
multiple interactions		 EXP Linuron results in decreased expression of EGFR mRNA
[Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of EGFR mRNA		 CTD PMID:12730624 PMID:25607892 NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382 		JBrowse link
G Eif4e eukaryotic translation initiation factor 4E decreases expression EXP Linuron results in decreased expression of EIF4E mRNA CTD PMID:28705778 NCBI chr 2:227,066,519...227,099,261
Ensembl chr 2:227,066,673...227,098,683 		JBrowse link
G Entpd1 ectonucleoside triphosphate diphosphohydrolase 1 increases expression
multiple interactions		 ISO Linuron results in increased expression of ENTPD1 mRNA
SIGMAR1 gene promotes the reaction [Linuron results in increased expression of ENTPD1 mRNA]; XBP1 gene promotes the reaction [Linuron results in increased expression of ENTPD1 mRNA]		 CTD PMID:30661753 NCBI chr 1:239,425,515...239,552,323
Ensembl chr 1:239,425,430...239,552,317 		JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of ERBB2 mRNA CTD PMID:25607892 NCBI chr10:83,411,197...83,435,078
Ensembl chr10:83,411,313...83,435,078 		JBrowse link
G Erbb3 erb-b2 receptor tyrosine kinase 3 multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of ERBB3 mRNA CTD PMID:25607892 NCBI chr 7:994,549...1,015,876
Ensembl chr 7:996,225...1,015,525 		JBrowse link
G Erbb4 erb-b2 receptor tyrosine kinase 4 multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of ERBB4 mRNA; [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of ERBB4 mRNA CTD PMID:25607892 NCBI chr 9:69,523,733...70,596,743
Ensembl chr 9:69,531,481...70,596,595 		JBrowse link
G Ern1 endoplasmic reticulum to nucleus signaling 1 increases activity
multiple interactions		 ISO Linuron results in increased activity of ERN1 protein
1-(2-(3,4-dichlorophenyl)ethyl)-4-methylpiperazine inhibits the reaction [Linuron promotes the reaction [[IL1B protein co-treated with TNF protein] results in increased expression of ERN1 protein modified form]]
Linuron promotes the reaction [ERN1 protein binds to SIGMAR1 protein]		 CTD PMID:30661753 NCBI chr10:91,326,889...91,421,201
Ensembl chr10:91,330,654...91,421,029 		JBrowse link
G Esr1 estrogen receptor 1 multiple interactions ISO
EXP		 Linuron binds to and results in increased activity of ESR1 protein
[Plasticizers co-treated with Fungicides, Industrial co-treated with Linuron co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with Dichlorodiphenyl Dichloroethylene co-treated with butylparaben co-treated with Acetaminophen] results in decreased expression of ESR1 mRNA		 CTD PMID:33049310 PMID:34383603 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002 		JBrowse link
G Esr2 estrogen receptor 2 multiple interactions ISO Linuron binds to and results in increased activity of ESR2 protein CTD PMID:33049310 NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919 		JBrowse link
G Fgfr2 fibroblast growth factor receptor 2 decreases expression EXP Linuron results in decreased expression of FGFR2 mRNA CTD PMID:12730624 NCBI chr 1:184,745,418...184,850,655
Ensembl chr 1:184,745,420...184,850,626 		JBrowse link
G Fmr1 fragile X messenger ribonucleoprotein 1 multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of FMR1 mRNA CTD PMID:25607892 NCBI chr  X:147,240,239...147,278,057
Ensembl chr  X:147,240,301...147,278,050 		JBrowse link
G Fshr follicle stimulating hormone receptor decreases expression EXP Linuron results in decreased expression of FSHR mRNA CTD PMID:36410587 NCBI chr 6:5,198,825...5,406,785
Ensembl chr 6:5,198,825...5,406,785 		JBrowse link
G Fyn FYN proto-oncogene, Src family tyrosine kinase multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of FYN mRNA CTD PMID:25607892 NCBI chr20:42,767,733...42,960,903
Ensembl chr20:42,766,369...42,959,911 		JBrowse link
G Gabra4 gamma-aminobutyric acid type A receptor subunit alpha 4 multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of GABRA4 mRNA CTD PMID:25607892 NCBI chr14:36,590,782...36,667,724
Ensembl chr14:36,590,782...36,665,844 		JBrowse link
G Gabrb1 gamma-aminobutyric acid type A receptor subunit beta1 multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of GABRB1 mRNA CTD PMID:25607892 NCBI chr14:36,068,725...36,548,946
Ensembl chr14:36,080,393...36,548,948 		JBrowse link
G Gdnf glial cell derived neurotrophic factor multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of GDNF mRNA CTD PMID:25607892 NCBI chr 2:56,894,022...56,919,935
Ensembl chr 2:56,895,010...56,917,209 		JBrowse link
G Gls glutaminase multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of GLS mRNA CTD PMID:25607892 NCBI chr 9:49,344,616...49,416,900
Ensembl chr 9:49,344,781...49,416,900 		JBrowse link
G Gpc1 glypican 1 decreases expression EXP Linuron results in decreased expression of GPC1 mRNA CTD PMID:12730624 NCBI chr 9:93,396,234...93,424,047
Ensembl chr 9:93,396,234...93,424,047 		JBrowse link
G Gria2 glutamate ionotropic receptor AMPA type subunit 2 multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of GRIA2 mRNA CTD PMID:25607892 NCBI chr 2:165,949,379...166,069,510
Ensembl chr 2:165,947,521...166,069,510 		JBrowse link
G Gria4 glutamate ionotropic receptor AMPA type subunit 4 multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of GRIA4 mRNA CTD PMID:25607892 NCBI chr 8:1,562,118...2,035,035
Ensembl chr 8:1,562,119...2,034,979 		JBrowse link
G Grid2 glutamate ionotropic receptor delta type subunit 2 multiple interactions EXP [Plasticizers co-treated with Fungicides, Industrial co-treated with Linuron co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with Dichlorodiphenyl Dichloroethylene co-treated with butylparaben co-treated with Acetaminophen] results in decreased expression of GRID2 mRNA CTD PMID:34383603 NCBI chr 4:92,415,019...93,892,472
Ensembl chr 4:92,415,230...93,889,355 		JBrowse link
G Grik1 glutamate ionotropic receptor kainate type subunit 1 multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of GRIK1 mRNA CTD PMID:25607892 NCBI chr11:27,169,739...27,571,131
Ensembl chr11:27,169,740...27,570,645 		JBrowse link
G Grik2 glutamate ionotropic receptor kainate type subunit 2 multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of GRIK2 mRNA CTD PMID:25607892 NCBI chr20:52,135,325...52,833,061
Ensembl chr20:52,133,851...52,838,375 		JBrowse link
G Grin1 glutamate ionotropic receptor NMDA type subunit 1 multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of GRIN1 mRNA CTD PMID:25607892 NCBI chr 3:8,103,680...8,130,603
Ensembl chr 3:8,103,680...8,130,603 		JBrowse link
G Grin2b glutamate ionotropic receptor NMDA type subunit 2B multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of GRIN2B mRNA CTD PMID:25607892 NCBI chr 4:168,580,824...169,044,110
Ensembl chr 4:168,599,546...169,042,279 		JBrowse link
G Grin2d glutamate ionotropic receptor NMDA type subunit 2D multiple interactions EXP [Plasticizers co-treated with Fungicides, Industrial co-treated with Linuron co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with Dichlorodiphenyl Dichloroethylene co-treated with butylparaben co-treated with Acetaminophen] results in decreased expression of GRIN2D mRNA CTD PMID:34383603 NCBI chr 1:96,306,871...96,346,994
Ensembl chr 1:96,308,365...96,344,793 		JBrowse link
G Grip1 glutamate receptor interacting protein 1 multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of GRIP1 mRNA CTD PMID:25607892 NCBI chr 7:54,934,856...55,592,274
Ensembl chr 7:54,934,250...55,592,273 		JBrowse link
G Hbg1 hemoglobin subunit gamma 1 decreases expression EXP Linuron results in decreased expression of HBG1 mRNA CTD PMID:16498641 NCBI chr 1:158,271,871...158,273,426
Ensembl chr 1:158,271,873...158,273,425 		JBrowse link
G Hes6 hes family bHLH transcription factor 6 multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of HES6 mRNA CTD PMID:25607892 NCBI chr 9:92,001,849...92,003,562
Ensembl chr 9:92,001,841...92,003,559 		JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha increases expression
multiple interactions		 ISO Linuron results in increased expression of HIF1A mRNA
XBP1 gene mutant form inhibits the reaction [Linuron results in increased expression of HIF1A mRNA]		 CTD PMID:30661753 NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261 		JBrowse link
G Hsd17b3 hydroxysteroid (17-beta) dehydrogenase 3 decreases expression EXP Linuron results in decreased expression of HSD17B3 mRNA CTD PMID:28007637 NCBI chr17:1,027,229...1,058,554
Ensembl chr17:1,027,229...1,058,554 		JBrowse link
G Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 decreases expression EXP Linuron results in decreased expression of HSD3B1 mRNA CTD PMID:36410587 NCBI chr 2:186,169,864...186,175,984
Ensembl chr 2:186,169,863...186,175,999 		JBrowse link
G Idi1 isopentenyl-diphosphate delta isomerase 1 decreases expression EXP Linuron results in decreased expression of IDI1 mRNA CTD PMID:16498641 NCBI chr17:61,629,592...61,637,357
Ensembl chr17:61,629,594...61,637,357 		JBrowse link
G Ifnar1 interferon alpha and beta receptor subunit 1 multiple interactions
increases expression		 ISO SIGMAR1 gene promotes the reaction [Linuron results in increased expression of IFNAR1 mRNA]; XBP1 gene promotes the reaction [Linuron results in increased expression of IFNAR1 mRNA] CTD PMID:30661753 NCBI chr11:30,725,774...30,752,227
Ensembl chr11:30,725,790...30,749,979 		JBrowse link
G Ifnb1 interferon beta 1 multiple interactions
increases expression		 ISO SIGMAR1 gene mutant form inhibits the reaction [Linuron results in increased expression of IFNB1 mRNA] CTD PMID:30661753 NCBI chr 5:103,020,758...103,021,595
Ensembl chr 5:103,020,969...103,021,523 		JBrowse link
G Ifng interferon gamma increases expression
multiple interactions		 ISO Linuron results in increased expression of IFNG mRNA
SIGMAR1 gene mutant form inhibits the reaction [Linuron results in increased expression of IFNG mRNA]; XBP1 gene mutant form inhibits the reaction [Linuron results in increased expression of IFNG mRNA]		 CTD PMID:30661753 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375 		JBrowse link
G Igf1 insulin-like growth factor 1 increases expression EXP Linuron results in increased expression of IGF1 mRNA CTD PMID:12730624 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296 		JBrowse link
G Igf1r insulin-like growth factor 1 receptor decreases expression EXP Linuron results in decreased expression of IGF1R mRNA CTD PMID:12730624 NCBI chr 1:121,549,831...121,838,548
Ensembl chr 1:121,550,743...121,831,777 		JBrowse link
G Igf2r insulin-like growth factor 2 receptor multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of IGF2R mRNA CTD PMID:25607892 NCBI chr 1:47,979,109...48,067,501
Ensembl chr 1:47,979,109...48,067,501 		JBrowse link
G Igfbp5 insulin-like growth factor binding protein 5 decreases expression EXP Linuron results in decreased expression of IGFBP5 mRNA CTD PMID:12730624 NCBI chr 9:74,452,371...74,464,953
Ensembl chr 9:74,448,382...74,465,156 		JBrowse link
G Il10 interleukin 10 increases expression
multiple interactions		 ISO Linuron results in increased expression of IL10 mRNA
XBP1 gene promotes the reaction [Linuron results in increased expression of IL10 mRNA]		 CTD PMID:30661753 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313 		JBrowse link
G Il10ra interleukin 10 receptor subunit alpha multiple interactions
increases expression		 ISO SIGMAR1 gene promotes the reaction [Linuron results in increased expression of IL10RA mRNA] CTD PMID:30661753 NCBI chr 8:45,563,009...45,578,041
Ensembl chr 8:45,563,137...45,578,061 		JBrowse link
G Il13 interleukin 13 increases expression
multiple interactions		 ISO Linuron results in increased expression of IL13 mRNA
XBP1 gene mutant form inhibits the reaction [Linuron results in increased expression of IL13 mRNA]		 CTD PMID:30661753 NCBI chr10:37,790,130...37,792,687
Ensembl chr10:37,790,130...37,792,737 		JBrowse link
G Il1b interleukin 1 beta multiple interactions
increases expression		 ISO 1-(2-(3,4-dichlorophenyl)ethyl)-4-methylpiperazine inhibits the reaction [[IL1B protein co-treated with TNF protein co-treated with Linuron] results in increased expression of RELA protein modified form]; 1-(2-(3,4-dichlorophenyl)ethyl)-4-methylpiperazine inhibits the reaction [[IL1B protein co-treated with TNF protein co-treated with Linuron] results in increased expression of XBP1 protein modified form]; 1-(2-(3,4-dichlorophenyl)ethyl)-4-methylpiperazine inhibits the reaction [[IL1B protein co-treated with TNF protein co-treated with Linuron] results in increased splicing of XBP1 mRNA]; 1-(2-(3,4-dichlorophenyl)ethyl)-4-methylpiperazine inhibits the reaction [Linuron promotes the reaction [[IL1B protein co-treated with TNF protein] results in increased expression of CCL2 mRNA]]; 1-(2-(3,4-dichlorophenyl)ethyl)-4-methylpiperazine inhibits the reaction [Linuron promotes the reaction [[IL1B protein co-treated with TNF protein] results in increased expression of CSF2 mRNA]]; 1-(2-(3,4-dichlorophenyl)ethyl)-4-methylpiperazine inhibits the reaction [Linuron promotes the reaction [[IL1B protein co-treated with TNF protein] results in increased expression of ERN1 protein modified form]]; 1-(2-(3,4-dichlorophenyl)ethyl)-4-methylpiperazine inhibits the reaction [Linuron promotes the reaction [[IL1B protein co-treated with TNF protein] results in increased expression of IL6 mRNA]]; 1-(2-(3,4-dichlorophenyl)ethyl)-4-methylpiperazine inhibits the reaction [Linuron promotes the reaction [[IL1B protein co-treated with TNF protein] results in increased expression of NOS2 mRNA]]; [IL1B protein co-treated with TNF protein co-treated with Linuron] promotes the reaction [XBP1 protein binds to NOS2 promoter]; [IL1B protein co-treated with TNF protein co-treated with Linuron] results in increased expression of RELA protein modified form; [IL1B protein co-treated with TNF protein co-treated with Linuron] results in increased expression of XBP1 protein modified form; [IL1B protein co-treated with TNF protein co-treated with Linuron] results in increased splicing of XBP1 mRNA; [IL1B protein co-treated with TNF protein] results in increased susceptibility to Linuron; Linuron promotes the reaction [[IL1B protein co-treated with TNF protein] results in increased expression of CCL2 mRNA]; Linuron promotes the reaction [[IL1B protein co-treated with TNF protein] results in increased expression of CSF2 mRNA]; Linuron promotes the reaction [[IL1B protein co-treated with TNF protein] results in increased expression of IL6 mRNA]; Linuron promotes the reaction [[IL1B protein co-treated with TNF protein] results in increased expression of NOS2 mRNA]; SIGMAR1 gene mutant form inhibits the reaction [Linuron results in increased expression of IL1B mRNA]; STF 083010 inhibits the reaction [Linuron promotes the reaction [[IL1B protein co-treated with TNF protein] results in increased expression of NOS2 mRNA]]; XBP1 gene mutant form inhibits the reaction [Linuron results in increased expression of IL1B mRNA]
1-(2-(3,4-dichlorophenyl)ethyl)-4-methylpiperazine inhibits the reaction [Linuron promotes the reaction [[IL1B protein co-treated with TNF protein] results in increased expression of NOS2 mRNA]]; Linuron promotes the reaction [[IL1B protein co-treated with TNF protein] results in increased expression of NOS2 mRNA]; STF 083010 inhibits the reaction [[Linuron co-treated with IL1B protein co-treated with TNF protein] results in increased splicing of XBP1 mRNA]; STF 083010 inhibits the reaction [Linuron promotes the reaction [[IL1B protein co-treated with TNF protein] results in increased expression of NOS2 mRNA]]		 CTD PMID:30661753 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il1rapl1 interleukin 1 receptor accessory protein-like 1 multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of IL1RAPL1 mRNA CTD PMID:25607892 NCBI chr  X:51,371,969...52,876,726
Ensembl chr  X:51,378,215...52,876,772 		JBrowse link
G Il21 interleukin 21 increases expression
multiple interactions		 ISO Linuron results in increased expression of IL21 mRNA
SIGMAR1 gene mutant form inhibits the reaction [Linuron results in increased expression of IL21 mRNA]		 CTD PMID:30661753 NCBI chr 2:120,117,105...120,127,012
Ensembl chr 2:120,119,444...120,126,996 		JBrowse link
G Il23a interleukin 23 subunit alpha increases expression
multiple interactions		 ISO Linuron results in increased expression of IL23A mRNA
SIGMAR1 gene mutant form inhibits the reaction [Linuron results in increased expression of IL23A mRNA]; XBP1 gene mutant form inhibits the reaction [Linuron results in increased expression of IL23A mRNA]		 CTD PMID:30661753 NCBI chr 7:721,809...723,923
Ensembl chr 7:721,809...723,923 		JBrowse link
G Il5 interleukin 5 increases expression
multiple interactions		 ISO Linuron results in increased expression of IL5 mRNA
XBP1 gene mutant form inhibits the reaction [Linuron results in increased expression of IL5 mRNA]		 CTD PMID:30661753 NCBI chr10:37,874,342...37,877,213
Ensembl chr10:37,874,342...37,877,213 		JBrowse link
G Il6 interleukin 6 multiple interactions
increases expression		 ISO 1-(2-(3,4-dichlorophenyl)ethyl)-4-methylpiperazine inhibits the reaction [Linuron promotes the reaction [[IL1B protein co-treated with TNF protein] results in increased expression of IL6 mRNA]]; Linuron promotes the reaction [[IL1B protein co-treated with TNF protein] results in increased expression of IL6 mRNA]; SIGMAR1 gene mutant form inhibits the reaction [Linuron results in increased expression of IL6 mRNA]; XBP1 gene mutant form inhibits the reaction [Linuron results in increased expression of IL6 mRNA] CTD PMID:30661753 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Inha inhibin subunit alpha decreases expression EXP Linuron results in decreased expression of INHA mRNA CTD PMID:36410587 NCBI chr 9:76,994,465...76,997,366
Ensembl chr 9:76,993,589...76,997,248 		JBrowse link
G Inhba inhibin subunit beta A decreases expression EXP Linuron results in decreased expression of INHBA mRNA CTD PMID:36410587 NCBI chr17:49,091,635...49,111,573
Ensembl chr17:49,095,920...49,108,982 		JBrowse link
G Irf3 interferon regulatory factor 3 increases expression
multiple interactions		 ISO Linuron results in increased expression of IRF3 mRNA
XBP1 gene promotes the reaction [Linuron results in increased expression of IRF3 mRNA]		 CTD PMID:30661753 NCBI chr 1:95,479,966...95,484,926
Ensembl chr 1:95,479,821...95,484,935 		JBrowse link
G Irf7 interferon regulatory factor 7 increases expression
multiple interactions		 ISO Linuron results in increased expression of IRF7 mRNA
XBP1 gene promotes the reaction [Linuron results in increased expression of IRF7 mRNA]		 CTD PMID:30661753 NCBI chr 1:196,367,380...196,370,943
Ensembl chr 1:196,367,361...196,370,832 		JBrowse link
G Irf9 interferon regulatory factor 9 increases expression
multiple interactions		 ISO Linuron results in increased expression of IRF9 mRNA
XBP1 gene promotes the reaction [Linuron results in increased expression of IRF9 mRNA]		 CTD PMID:30661753 NCBI chr15:29,095,474...29,101,924
Ensembl chr15:29,095,789...29,101,236 		JBrowse link
G Kiss1 KiSS-1 metastasis-suppressor multiple interactions EXP [Plasticizers co-treated with Fungicides, Industrial co-treated with Linuron co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with Dichlorodiphenyl Dichloroethylene co-treated with butylparaben co-treated with Acetaminophen] results in decreased expression of KISS1 mRNA CTD PMID:34383603 NCBI chr13:44,775,106...44,780,707
Ensembl chr13:44,774,823...44,780,612 		JBrowse link
G Klk1c10 kallikrein 1-related peptidase C10 decreases expression
increases secretion		 ISO Linuron results in decreased expression of KLK3 mRNA
Linuron results in increased secretion of KLK3 protein		 CTD PMID:20363314 PMID:33932781 NCBI chr 1:94,402,993...94,407,052
Ensembl chr 1:94,402,993...94,407,052 		JBrowse link
G Lhcgr luteinizing hormone/choriogonadotropin receptor decreases expression EXP Linuron results in decreased expression of LHCGR mRNA CTD PMID:36410587 NCBI chr 6:5,661,871...5,728,109
Ensembl chr 6:5,661,871...5,724,521 		JBrowse link
G Lif LIF, interleukin 6 family cytokine increases expression
multiple interactions		 ISO Linuron results in increased expression of LIF mRNA
SIGMAR1 gene promotes the reaction [Linuron results in increased expression of LIF mRNA]; XBP1 gene promotes the reaction [Linuron results in increased expression of LIF mRNA]		 CTD PMID:30661753 NCBI chr14:79,131,049...79,140,486
Ensembl chr14:79,134,574...79,140,482 		JBrowse link
G Lrrc7 leucine rich repeat containing 7 multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of LRRC7 mRNA CTD PMID:25607892 NCBI chr 2:247,146,616...247,634,945
Ensembl chr 2:247,147,752...247,634,547 		JBrowse link
G Magi2 membrane associated guanylate kinase, WW and PDZ domain containing 2 multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of MAGI2 mRNA CTD PMID:25607892 NCBI chr 4:14,386,389...15,870,036
Ensembl chr 4:14,386,399...15,870,240 		JBrowse link
G Mdga2 MAM domain containing glycosylphosphatidylinositol anchor 2 multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of MDGA2 mRNA CTD PMID:25607892 NCBI chr 6:84,746,422...85,608,640
Ensembl chr 6:84,761,941...85,608,126 		JBrowse link
G Mfn2 mitofusin 2 decreases expression EXP Linuron results in decreased expression of MFN2 mRNA CTD PMID:28705778 NCBI chr 5:158,304,285...158,335,502
Ensembl chr 5:158,304,287...158,335,342 		JBrowse link
G Mmp12 matrix metallopeptidase 12 increases expression
multiple interactions		 ISO Linuron results in increased expression of MMP12 mRNA
SIGMAR1 gene mutant form inhibits the reaction [Linuron results in increased expression of MMP12 mRNA]; XBP1 gene mutant form inhibits the reaction [Linuron results in increased expression of MMP12 mRNA]		 CTD PMID:30661753 NCBI chr 8:4,581,785...4,591,687
Ensembl chr 8:4,581,785...4,599,611 		JBrowse link
G Msmb microseminoprotein, beta decreases expression ISO Linuron results in decreased expression of MSMB mRNA CTD PMID:33932781 NCBI chr16:7,366,536...7,387,124
Ensembl chr16:7,366,536...7,387,123 		JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor decreases expression EXP Linuron results in decreased expression of MYC mRNA CTD PMID:28705778 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630 		JBrowse link
G Myom2 myomesin 2 increases expression EXP Linuron results in increased expression of MYOM2 mRNA CTD PMID:16498641 NCBI chr16:74,520,148...74,592,658
Ensembl chr16:74,520,157...74,592,772 		JBrowse link
G Nf1 neurofibromin 1 multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of NF1 mRNA CTD PMID:25607892 NCBI chr10:64,306,027...64,539,112
Ensembl chr10:64,306,301...64,536,658 		JBrowse link
G Nlgn1 neuroligin 1 multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of NLGN1 mRNA CTD PMID:25607892 NCBI chr 2:108,256,236...109,181,530
Ensembl chr 2:108,257,824...109,002,464 		JBrowse link
G Nos2 nitric oxide synthase 2 increases expression
multiple interactions		 ISO Linuron results in increased expression of NOS2 mRNA
1-(2-(3,4-dichlorophenyl)ethyl)-4-methylpiperazine inhibits the reaction [Linuron promotes the reaction [[IL1B protein co-treated with TNF protein] results in increased expression of NOS2 mRNA]]; [IL1B protein co-treated with TNF protein co-treated with Linuron] promotes the reaction [XBP1 protein binds to NOS2 promoter]; Linuron promotes the reaction [[IL1B protein co-treated with TNF protein] results in increased expression of NOS2 mRNA]; SIGMAR1 gene mutant form inhibits the reaction [Linuron results in increased expression of NOS2 mRNA]; STF 083010 inhibits the reaction [Linuron promotes the reaction [[IL1B protein co-treated with TNF protein] results in increased expression of NOS2 mRNA]]; XBP1 gene mutant form inhibits the reaction [Linuron results in increased expression of NOS2 mRNA]
1-(2-(3,4-dichlorophenyl)ethyl)-4-methylpiperazine inhibits the reaction [Linuron promotes the reaction [[IL1B protein co-treated with TNF protein] results in increased expression of NOS2 mRNA]]; Linuron promotes the reaction [[IL1B protein co-treated with TNF protein] results in increased expression of NOS2 mRNA]; STF 083010 inhibits the reaction [Linuron promotes the reaction [[IL1B protein co-treated with TNF protein] results in increased expression of NOS2 mRNA]]		 CTD PMID:30661753 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210 		JBrowse link
G Notch2 notch receptor 2 decreases expression
multiple interactions		 EXP Linuron results in decreased expression of NOTCH2 mRNA
[Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] affects the expression of NOTCH2 mRNA		 CTD PMID:12730624 PMID:25607892 NCBI chr 2:185,610,594...185,744,088
Ensembl chr 2:185,610,589...185,744,088 		JBrowse link
G Notch3 notch receptor 3 multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of NOTCH3 mRNA CTD PMID:25607892 NCBI chr 7:11,132,984...11,184,025
Ensembl chr 7:11,133,706...11,184,025 		JBrowse link
G Notch4 notch receptor 4 multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of NOTCH4 mRNA CTD PMID:25607892 NCBI chr20:4,160,362...4,184,466
Ensembl chr20:4,160,445...4,184,465 		JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions ISO Linuron binds to and results in increased activity of NR1I2 protein
[Chlorfenvinphos co-treated with ethion co-treated with Linuron] results in increased activity of NR1I2 protein; Linuron binds to and results in increased activity of NR1I2 protein		 CTD PMID:21115097 PMID:25028461 PMID:33049310 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658 		JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 multiple interactions EXP [Plasticizers co-treated with Fungicides, Industrial co-treated with Linuron co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with Dichlorodiphenyl Dichloroethylene co-treated with butylparaben co-treated with Acetaminophen] results in decreased expression of NR3C1 mRNA CTD PMID:34383603 NCBI chr18:31,271,681...31,393,320
Ensembl chr18:31,271,681...31,393,375 		JBrowse link
G Nrcam neuronal cell adhesion molecule multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of NRCAM mRNA CTD PMID:25607892 NCBI chr 6:61,402,813...61,698,536
Ensembl chr 6:61,329,863...61,702,992 		JBrowse link
G Nrg1 neuregulin 1 multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of NRG1 mRNA; [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of NRG1 mRNA CTD PMID:25607892 NCBI chr16:59,250,658...60,304,519
Ensembl chr16:59,250,854...60,296,884 		JBrowse link
G Nrxn1 neurexin 1 multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of NRXN1 mRNA CTD PMID:25607892 NCBI chr 6:3,177,788...4,323,848
Ensembl chr 6:3,177,897...4,322,710 		JBrowse link
G Nrxn2 neurexin 2 multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of NRXN2 mRNA CTD PMID:25607892 NCBI chr 1:203,726,420...203,842,301
Ensembl chr 1:203,735,753...203,842,297 		JBrowse link
G Ntrk2 neurotrophic receptor tyrosine kinase 2 multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of NTRK2 mRNA CTD PMID:25607892 NCBI chr17:5,558,992...5,870,299
Ensembl chr17:5,559,043...5,869,136 		JBrowse link
G Oxt oxytocin/neurophysin I prepropeptide multiple interactions EXP [Plasticizers co-treated with Fungicides, Industrial co-treated with Linuron co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with Dichlorodiphenyl Dichloroethylene co-treated with butylparaben co-treated with Acetaminophen] results in decreased expression of OXT mRNA CTD PMID:34383603 NCBI chr 3:117,782,650...117,783,490
Ensembl chr 3:117,782,650...117,783,490 		JBrowse link
G Pcna proliferating cell nuclear antigen decreases expression EXP Linuron results in decreased expression of PCNA mRNA; Linuron results in decreased expression of PCNA protein CTD PMID:28007637 PMID:28705778 NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995 		JBrowse link
G Pgr progesterone receptor multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of PGR mRNA CTD PMID:25607892 NCBI chr 8:6,072,673...6,131,552
Ensembl chr 8:6,072,673...6,131,344 		JBrowse link
G Pomc proopiomelanocortin multiple interactions EXP [Plasticizers co-treated with Fungicides, Industrial co-treated with Linuron co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with Dichlorodiphenyl Dichloroethylene co-treated with butylparaben co-treated with Acetaminophen] affects the expression of POMC mRNA CTD PMID:34383603 NCBI chr 6:26,939,844...26,945,666
Ensembl chr 6:26,939,837...26,945,664 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma multiple interactions ISO Linuron binds to and results in increased activity of PPARG protein CTD PMID:33049310 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468 		JBrowse link
G Ppp1r1b protein phosphatase 1, regulatory (inhibitor) subunit 1B multiple interactions EXP [Plasticizers co-treated with Fungicides, Industrial co-treated with Linuron co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with Dichlorodiphenyl Dichloroethylene co-treated with butylparaben co-treated with Acetaminophen] results in decreased expression of PPP1R1B mRNA CTD PMID:34383603 NCBI chr10:83,347,731...83,356,775
Ensembl chr10:83,347,731...83,356,775 		JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of PRKN mRNA CTD PMID:25607892 NCBI chr 1:48,688,651...49,882,520
Ensembl chr 1:48,690,556...49,882,555 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO [Linuron binds to and results in decreased activity of PTGS2 protein] which results in decreased chemical synthesis of and results in decreased secretion of Prostaglandin D2 CTD PMID:26359731 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO 1-(2-(3,4-dichlorophenyl)ethyl)-4-methylpiperazine inhibits the reaction [[IL1B protein co-treated with TNF protein co-treated with Linuron] results in increased expression of RELA protein modified form]; [IL1B protein co-treated with TNF protein co-treated with Linuron] results in increased expression of RELA protein modified form CTD PMID:30661753 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484 		JBrowse link
G Reln reelin multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of RELN mRNA CTD PMID:25607892 NCBI chr 4:12,736,177...13,162,956
Ensembl chr 4:12,736,130...13,162,211 		JBrowse link
G Robo1 roundabout guidance receptor 1 multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of ROBO1 mRNA CTD PMID:25607892 NCBI chr11:10,580,863...11,621,675
Ensembl chr11:10,580,908...11,620,203 		JBrowse link
G Rps6kb2 ribosomal protein S6 kinase B2 decreases expression EXP Linuron results in decreased expression of RPS6KB2 mRNA CTD PMID:28705778 NCBI chr 1:201,451,265...201,458,096
Ensembl chr 1:201,451,265...201,458,078 		JBrowse link
G Rptor regulatory associated protein of MTOR, complex 1 decreases expression EXP Linuron results in decreased expression of RPTOR mRNA CTD PMID:28705778 NCBI chr10:104,878,487...105,176,986
Ensembl chr10:104,878,487...105,176,983 		JBrowse link
G Rxra retinoid X receptor alpha multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of RXRA mRNA CTD PMID:25607892 NCBI chr 3:10,989,832...11,076,366
Ensembl chr 3:10,989,832...11,073,712 		JBrowse link
G Shank2 SH3 and multiple ankyrin repeat domains 2 multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of SHANK2 mRNA CTD PMID:25607892 NCBI chr 1:199,146,210...199,590,962
Ensembl chr 1:199,169,429...199,589,394 		JBrowse link
G Shbg sex hormone binding globulin decreases expression EXP Linuron results in decreased expression of SHBG mRNA CTD PMID:28705778 NCBI chr10:54,332,939...54,350,409
Ensembl chr10:54,332,941...54,351,057 		JBrowse link
G Sigmar1 sigma non-opioid intracellular receptor 1 increases activity
multiple interactions
decreases response to substance		 ISO Linuron results in increased activity of SIGMAR1 protein
Linuron promotes the reaction [ERN1 protein binds to SIGMAR1 protein]
SIGMAR1 gene mutant form results in decreased susceptibility to Linuron
SIGMAR1 gene mutant form inhibits the reaction [Linuron results in increased expression of ARG1 mRNA]; SIGMAR1 gene mutant form inhibits the reaction [Linuron results in increased expression of CCL1 mRNA]; SIGMAR1 gene mutant form inhibits the reaction [Linuron results in increased expression of CCL17 mRNA]; SIGMAR1 gene mutant form inhibits the reaction [Linuron results in increased expression of CCL20 mRNA]; SIGMAR1 gene mutant form inhibits the reaction [Linuron results in increased expression of CCL4 mRNA]; SIGMAR1 gene mutant form inhibits the reaction [Linuron results in increased expression of CCR2 mRNA]; SIGMAR1 gene mutant form inhibits the reaction [Linuron results in increased expression of CSF2 mRNA]; SIGMAR1 gene mutant form inhibits the reaction [Linuron results in increased expression of CXCL10 mRNA]; SIGMAR1 gene mutant form inhibits the reaction [Linuron results in increased expression of IFNB1 mRNA]; SIGMAR1 gene mutant form inhibits the reaction [Linuron results in increased expression of IFNG mRNA]; SIGMAR1 gene mutant form inhibits the reaction [Linuron results in increased expression of IL1B mRNA]; SIGMAR1 gene mutant form inhibits the reaction [Linuron results in increased expression of IL21 mRNA]; SIGMAR1 gene mutant form inhibits the reaction [Linuron results in increased expression of IL23A mRNA]; SIGMAR1 gene mutant form inhibits the reaction [Linuron results in increased expression of IL6 mRNA]; SIGMAR1 gene mutant form inhibits the reaction [Linuron results in increased expression of MMP12 mRNA]; SIGMAR1 gene mutant form inhibits the reaction [Linuron results in increased expression of NOS2 mRNA]; SIGMAR1 gene promotes the reaction [Linuron results in increased expression of AHR mRNA]; SIGMAR1 gene promotes the reaction [Linuron results in increased expression of CSPG4 mRNA]; SIGMAR1 gene promotes the reaction [Linuron results in increased expression of ENTPD1 mRNA]; SIGMAR1 gene promotes the reaction [Linuron results in increased expression of IFNAR1 mRNA]; SIGMAR1 gene promotes the reaction [Linuron results in increased expression of IL10RA mRNA]; SIGMAR1 gene promotes the reaction [Linuron results in increased expression of LIF mRNA]; SIGMAR1 gene promotes the reaction [Linuron results in increased expression of TGFB2 mRNA]		 CTD PMID:30661753 NCBI chr 5:56,904,155...56,907,012
Ensembl chr 5:56,904,159...56,907,017 		JBrowse link
G Slc1a2 solute carrier family 1 member 2 multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of SLC1A2 mRNA CTD PMID:25607892 NCBI chr 3:89,005,129...89,135,469
Ensembl chr 3:89,005,129...89,126,498 		JBrowse link
G Slc1a6 solute carrier family 1 member 6 multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of SLC1A6 mRNA CTD PMID:25607892 NCBI chr 7:10,841,836...10,870,424
Ensembl chr 7:10,841,837...10,870,449 		JBrowse link
G Slit1 slit guidance ligand 1 multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of SLIT1 mRNA CTD PMID:25607892 NCBI chr 1:240,409,559...240,558,127
Ensembl chr 1:240,409,561...240,558,127 		JBrowse link
G Sptbn2 spectrin, beta, non-erythrocytic 2 multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of SPTBN2 mRNA CTD PMID:25607892 NCBI chr 1:202,002,970...202,045,343
Ensembl chr 1:202,002,970...202,044,283 		JBrowse link
G Srd5a1 steroid 5 alpha-reductase 1 decreases expression EXP Linuron results in decreased expression of SRD5A1 mRNA CTD PMID:28705778 NCBI chr 1:33,686,069...33,720,468
Ensembl chr 1:33,686,391...33,720,461 		JBrowse link
G Srd5a2 steroid 5 alpha-reductase 2 decreases activity ISO Linuron results in decreased activity of SRD5A2 protein CTD PMID:17218080 NCBI chr 6:21,426,225...21,465,727
Ensembl chr 6:21,426,215...21,462,112 		JBrowse link
G Star steroidogenic acute regulatory protein decreases expression EXP Linuron results in decreased expression of STAR mRNA CTD PMID:28705778 NCBI chr16:66,267,094...66,274,368
Ensembl chr16:66,264,807...66,271,672 		JBrowse link
G Stmn2 stathmin 2 multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of STMN2 mRNA CTD PMID:25607892 NCBI chr 2:93,204,690...93,252,011
Ensembl chr 2:93,204,692...93,252,011 		JBrowse link
G Sts steroid sulfatase multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of STS mRNA CTD PMID:25607892 NCBI chr  X:42,225,131...42,233,403
Ensembl chr  X:42,225,372...42,233,402 		JBrowse link
G Stxbp1 syntaxin binding protein 1 multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of STXBP1 mRNA CTD PMID:25607892 NCBI chr 3:16,076,725...16,138,431
Ensembl chr 3:16,076,391...16,138,369 		JBrowse link
G Syngap1 synaptic Ras GTPase activating protein 1 multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of SYNGAP1 mRNA CTD PMID:25607892 NCBI chr20:5,026,366...5,056,659
Ensembl chr20:5,026,364...5,056,672 		JBrowse link
G Syp synaptophysin multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] affects the expression of SYP mRNA CTD PMID:25607892 NCBI chr  X:14,849,444...14,864,553
Ensembl chr  X:14,849,444...14,864,745 		JBrowse link
G Tff1 trefoil factor 1 increases expression ISO Linuron results in increased expression of TFF1 mRNA CTD PMID:35307500 NCBI chr20:9,235,736...9,239,597
Ensembl chr20:9,235,736...9,239,597 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of TGFB1 mRNA CTD PMID:25607892 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847 		JBrowse link
G Tgfb2 transforming growth factor, beta 2 multiple interactions
increases expression		 ISO SIGMAR1 gene promotes the reaction [Linuron results in increased expression of TGFB2 mRNA]; XBP1 gene promotes the reaction [Linuron results in increased expression of TGFB2 mRNA] CTD PMID:30661753 NCBI chr13:98,160,075...98,261,771
Ensembl chr13:98,160,087...98,261,405 		JBrowse link
G Tgfb3 transforming growth factor, beta 3 increases expression
multiple interactions		 ISO Linuron results in increased expression of TGFB3 mRNA
XBP1 gene promotes the reaction [Linuron results in increased expression of TGFB3 mRNA]		 CTD PMID:30661753 NCBI chr 6:105,704,058...105,726,661
Ensembl chr 6:105,704,236...105,726,564 		JBrowse link
G Th tyrosine hydroxylase multiple interactions EXP [Plasticizers co-treated with Fungicides, Industrial co-treated with Linuron co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with Dichlorodiphenyl Dichloroethylene co-treated with butylparaben co-treated with Acetaminophen] results in decreased expression of TH mRNA CTD PMID:34383603 NCBI chr 1:198,071,500...198,078,832
Ensembl chr 1:198,071,503...198,109,767 		JBrowse link
G Thra thyroid hormone receptor alpha multiple interactions ISO Linuron binds to and results in increased activity of THRA protein CTD PMID:33049310 NCBI chr10:83,701,885...83,729,408
Ensembl chr10:83,700,755...83,729,936 		JBrowse link
G Timp3 TIMP metallopeptidase inhibitor 3 affects expression EXP Linuron affects the expression of TIMP3 mRNA CTD PMID:12730624 NCBI chr 7:17,520,827...17,571,850
Ensembl chr 7:17,521,919...17,571,839 		JBrowse link
G Tlr5 toll-like receptor 5 increases expression
multiple interactions		 ISO Linuron results in increased expression of TLR5 mRNA
XBP1 gene mutant form inhibits the reaction [Linuron results in increased expression of TLR5 mRNA]		 CTD PMID:30661753 NCBI chr13:94,634,778...94,658,992
Ensembl chr13:94,634,801...94,657,738 		JBrowse link
G Tnf tumor necrosis factor multiple interactions
increases expression		 ISO 1-(2-(3,4-dichlorophenyl)ethyl)-4-methylpiperazine inhibits the reaction [Linuron promotes the reaction [[IL1B protein co-treated with TNF protein] results in increased expression of NOS2 mRNA]]; Linuron promotes the reaction [[IL1B protein co-treated with TNF protein] results in increased expression of NOS2 mRNA]; STF 083010 inhibits the reaction [[Linuron co-treated with IL1B protein co-treated with TNF protein] results in increased splicing of XBP1 mRNA]; STF 083010 inhibits the reaction [Linuron promotes the reaction [[IL1B protein co-treated with TNF protein] results in increased expression of NOS2 mRNA]]
1-(2-(3,4-dichlorophenyl)ethyl)-4-methylpiperazine inhibits the reaction [[IL1B protein co-treated with TNF protein co-treated with Linuron] results in increased expression of RELA protein modified form]; 1-(2-(3,4-dichlorophenyl)ethyl)-4-methylpiperazine inhibits the reaction [[IL1B protein co-treated with TNF protein co-treated with Linuron] results in increased expression of XBP1 protein modified form]; 1-(2-(3,4-dichlorophenyl)ethyl)-4-methylpiperazine inhibits the reaction [[IL1B protein co-treated with TNF protein co-treated with Linuron] results in increased splicing of XBP1 mRNA]; 1-(2-(3,4-dichlorophenyl)ethyl)-4-methylpiperazine inhibits the reaction [Linuron promotes the reaction [[IL1B protein co-treated with TNF protein] results in increased expression of CCL2 mRNA]]; 1-(2-(3,4-dichlorophenyl)ethyl)-4-methylpiperazine inhibits the reaction [Linuron promotes the reaction [[IL1B protein co-treated with TNF protein] results in increased expression of CSF2 mRNA]]; 1-(2-(3,4-dichlorophenyl)ethyl)-4-methylpiperazine inhibits the reaction [Linuron promotes the reaction [[IL1B protein co-treated with TNF protein] results in increased expression of ERN1 protein modified form]]; 1-(2-(3,4-dichlorophenyl)ethyl)-4-methylpiperazine inhibits the reaction [Linuron promotes the reaction [[IL1B protein co-treated with TNF protein] results in increased expression of IL6 mRNA]]; 1-(2-(3,4-dichlorophenyl)ethyl)-4-methylpiperazine inhibits the reaction [Linuron promotes the reaction [[IL1B protein co-treated with TNF protein] results in increased expression of NOS2 mRNA]]; [IL1B protein co-treated with TNF protein co-treated with Linuron] promotes the reaction [XBP1 protein binds to NOS2 promoter]; [IL1B protein co-treated with TNF protein co-treated with Linuron] results in increased expression of RELA protein modified form; [IL1B protein co-treated with TNF protein co-treated with Linuron] results in increased expression of XBP1 protein modified form; [IL1B protein co-treated with TNF protein co-treated with Linuron] results in increased splicing of XBP1 mRNA; [IL1B protein co-treated with TNF protein] results in increased susceptibility to Linuron; Linuron promotes the reaction [[IL1B protein co-treated with TNF protein] results in increased expression of CCL2 mRNA]; Linuron promotes the reaction [[IL1B protein co-treated with TNF protein] results in increased expression of CSF2 mRNA]; Linuron promotes the reaction [[IL1B protein co-treated with TNF protein] results in increased expression of IL6 mRNA]; Linuron promotes the reaction [[IL1B protein co-treated with TNF protein] results in increased expression of NOS2 mRNA]; STF 083010 inhibits the reaction [Linuron promotes the reaction [[IL1B protein co-treated with TNF protein] results in increased expression of NOS2 mRNA]]; XBP1 gene mutant form inhibits the reaction [Linuron results in increased expression of TNF mRNA]		 CTD PMID:30661753 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tsc1 TSC complex subunit 1 increases expression EXP Linuron results in increased expression of TSC1 mRNA CTD PMID:28705778 NCBI chr 3:11,969,547...12,018,591
Ensembl chr 3:11,979,729...12,015,674 		JBrowse link
G Tsc2 TSC complex subunit 2 multiple interactions
increases expression		 EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of TSC2 mRNA
Linuron results in increased expression of TSC2 mRNA		 CTD PMID:25607892 PMID:28705778 NCBI chr10:13,621,135...13,655,773
Ensembl chr10:13,621,136...13,655,951 		JBrowse link
G Unc5b unc-5 netrin receptor B multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of UNC5B mRNA CTD PMID:25607892 NCBI chr20:28,697,726...28,764,474
Ensembl chr20:28,697,726...28,764,537 		JBrowse link
G Xbp1 X-box binding protein 1 decreases response to substance
increases activity
multiple interactions		 ISO XBP1 gene mutant form results in decreased susceptibility to Linuron
Linuron results in increased activity of XBP1 protein
1-(2-(3,4-dichlorophenyl)ethyl)-4-methylpiperazine inhibits the reaction [[IL1B protein co-treated with TNF protein co-treated with Linuron] results in increased expression of XBP1 protein modified form]; 1-(2-(3,4-dichlorophenyl)ethyl)-4-methylpiperazine inhibits the reaction [[IL1B protein co-treated with TNF protein co-treated with Linuron] results in increased splicing of XBP1 mRNA]; [IL1B protein co-treated with TNF protein co-treated with Linuron] promotes the reaction [XBP1 protein binds to NOS2 promoter]; [IL1B protein co-treated with TNF protein co-treated with Linuron] results in increased expression of XBP1 protein modified form; [IL1B protein co-treated with TNF protein co-treated with Linuron] results in increased splicing of XBP1 mRNA; XBP1 gene mutant form inhibits the reaction [Linuron results in increased expression of ARG1 mRNA]; XBP1 gene mutant form inhibits the reaction [Linuron results in increased expression of CCL1 mRNA]; XBP1 gene mutant form inhibits the reaction [Linuron results in increased expression of CCL2 mRNA]; XBP1 gene mutant form inhibits the reaction [Linuron results in increased expression of CCL20 mRNA]; XBP1 gene mutant form inhibits the reaction [Linuron results in increased expression of CCR2 mRNA]; XBP1 gene mutant form inhibits the reaction [Linuron results in increased expression of CSF2 mRNA]; XBP1 gene mutant form inhibits the reaction [Linuron results in increased expression of HIF1A mRNA]; XBP1 gene mutant form inhibits the reaction [Linuron results in increased expression of IFNG mRNA]; XBP1 gene mutant form inhibits the reaction [Linuron results in increased expression of IL13 mRNA]; XBP1 gene mutant form inhibits the reaction [Linuron results in increased expression of IL1B mRNA]; XBP1 gene mutant form inhibits the reaction [Linuron results in increased expression of IL23A mRNA]; XBP1 gene mutant form inhibits the reaction [Linuron results in increased expression of IL5 mRNA]; XBP1 gene mutant form inhibits the reaction [Linuron results in increased expression of IL6 mRNA]; XBP1 gene mutant form inhibits the reaction [Linuron results in increased expression of MMP12 mRNA]; XBP1 gene mutant form inhibits the reaction [Linuron results in increased expression of NOS2 mRNA]; XBP1 gene mutant form inhibits the reaction [Linuron results in increased expression of TLR5 mRNA]; XBP1 gene mutant form inhibits the reaction [Linuron results in increased expression of TNF mRNA]; XBP1 gene promotes the reaction [Linuron results in increased expression of AHR mRNA]; XBP1 gene promotes the reaction [Linuron results in increased expression of ARNT mRNA]; XBP1 gene promotes the reaction [Linuron results in increased expression of CNTF mRNA]; XBP1 gene promotes the reaction [Linuron results in increased expression of CSPG4 mRNA]; XBP1 gene promotes the reaction [Linuron results in increased expression of CXCL12 mRNA]; XBP1 gene promotes the reaction [Linuron results in increased expression of CYP1B1 mRNA]; XBP1 gene promotes the reaction [Linuron results in increased expression of ENTPD1 mRNA]; XBP1 gene promotes the reaction [Linuron results in increased expression of IFNAR1 mRNA]; XBP1 gene promotes the reaction [Linuron results in increased expression of IL10 mRNA]; XBP1 gene promotes the reaction [Linuron results in increased expression of IRF3 mRNA]; XBP1 gene promotes the reaction [Linuron results in increased expression of IRF7 mRNA]; XBP1 gene promotes the reaction [Linuron results in increased expression of IRF9 mRNA]; XBP1 gene promotes the reaction [Linuron results in increased expression of LIF mRNA]; XBP1 gene promotes the reaction [Linuron results in increased expression of TGFB2 mRNA]; XBP1 gene promotes the reaction [Linuron results in increased expression of TGFB3 mRNA]
STF 083010 inhibits the reaction [[Linuron co-treated with IL1B protein co-treated with TNF protein] results in increased splicing of XBP1 mRNA]		 CTD PMID:30661753 NCBI chr14:80,390,629...80,395,713
Ensembl chr14:80,390,643...80,395,693 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19911
    role 19854
      application 19722
        agrochemical 16894
          linuron 193
Path 2
Term Annotations click to browse term
  CHEBI ontology 19911
    subatomic particle 19909
      composite particle 19909
        hadron 19880
          baryon 19880
            nucleon 19909
              atomic nucleus 19880
                atom 19909
                  main group element atom 19849
                    p-block element atom 19849
                      carbon group element atom 19766
                        carbon atom 19785
                          organic molecular entity 19785
                            heteroorganic entity 19541
                              organochalcogen compound 19301
                                organooxygen compound 19193
                                  carbon oxoacid 18681
                                    carboxylic acid 18678
                                      carboacyl group 17728
                                        univalent carboacyl group 17728
                                          carbamoyl group 17548
                                            carboxamide 17580
                                              monocarboxylic acid amide 15752
                                                urea 6228
                                                  ureas 6226
                                                    phenylureas 2625
                                                      linuron 193
paths to the root