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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:isoprenaline
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Accession:CHEBI:64317 term browser browse the term
Definition:A secondary amino compound that is noradrenaline in which one of the hydrogens attached to the nitrogen is replaced by an isopropyl group. A sympathomimetic acting almost exclusively on beta-adrenergic receptors, it is used (mainly as the hydrochloride salt) as a bronghodilator and heart stimulant for the management of a variety of cardiac disorders.
Synonyms:exact_synonym: 4-[1-hydroxy-2-(propan-2-ylamino)ethyl]benzene-1,2-diol
 related_synonym: 1-(3,4-dihydroxyphenyl)-2-(isopropylamino)ethanol;   1-(3,4-dihydroxyphenyl)-2-isopropylaminoethanol;   3,4-dihydroxy-alpha-[(isopropylamino)methyl]benzyl alcohol;   Formula=C11H17NO3;   InChI=1S/C11H17NO3/c1-7(2)12-6-11(15)8-3-4-9(13)10(14)5-8/h3-5,7,11-15H,6H2,1-2H3;   InChIKey=JWZZKOKVBUJMES-UHFFFAOYSA-N;   N-isopropyl-beta-dihydroxyphenyl-beta-hydroxyethylamine;   N-isopropylnoradrenaline;   N-isopropylnorepinephrine;   SMILES=CC(C)NCC(O)c1ccc(O)c(O)c1;   alpha-(isopropylaminomethyl)protocatechuyl alcohol;   isoprenalina;   isoprenalinum;   isopropyl noradrenaline;   isoproterenol
 xref: CAS:7683-59-2;   DrugBank:DB01064;   Drug_Central:1499;   KEGG:C07056;   KEGG:D08090;   LINCS:LSM-4311
 xref_mesh: MESH:D007545
 xref: Patent:DE723278;   Patent:US2308232;   Reaxys:2213857;   Wikipedia:Isoprenaline


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isoprenaline term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A2m alpha-2-macroglobulin increases expression ISO Isoproterenol results in increased expression of A2M mRNA CTD PMID:21335049 NCBI chr 4:154,897,770...154,947,787
Ensembl chr 4:154,897,877...154,947,786 		JBrowse link
G Abca1 ATP binding cassette subfamily A member 1 increases expression ISO Isoproterenol results in increased expression of ABCA1 mRNA CTD PMID:20003209 NCBI chr 5:67,678,267...67,801,162
Ensembl chr 5:67,681,297...67,801,170 		JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A increases expression ISO Isoproterenol results in increased expression of ABCB1A mRNA CTD PMID:20003209 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709 		JBrowse link
G Abcb4 ATP binding cassette subfamily B member 4 decreases expression EXP
ISO		 Isoproterenol results in decreased expression of ABCB4 mRNA CTD PMID:24286936 NCBI chr 4:25,150,998...25,209,489
Ensembl chr 4:25,151,953...25,209,202 		JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 decreases expression
increases expression		 ISO
EXP		 Isoproterenol results in decreased expression of ABCC3 mRNA
Isoproterenol results in increased expression of ABCC3 mRNA		 CTD PMID:21335049 PMID:24286936 NCBI chr10:79,296,681...79,342,749
Ensembl chr10:79,296,693...79,342,595 		JBrowse link
G Abcc4 ATP binding cassette subfamily C member 4 increases expression ISO Isoproterenol results in increased expression of ABCC4 mRNA CTD PMID:20003209 NCBI chr15:95,541,186...95,774,898
Ensembl chr15:95,542,315...95,774,283 		JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 increases expression ISO Isoproterenol results in increased expression of ABCG2 mRNA CTD PMID:20003209 NCBI chr 4:87,676,241...87,802,757
Ensembl chr 4:87,745,319...87,802,409 		JBrowse link
G Abhd2 abhydrolase domain containing 2, acylglycerol lipase increases expression EXP Isoproterenol results in increased expression of ABHD2 mRNA CTD PMID:20211217 NCBI chr 1:133,217,403...133,298,564
Ensembl chr 1:133,217,375...133,299,061 		JBrowse link
G Abhd4 abhydrolase domain containing 4, N-acyl phospholipase B increases expression ISO Isoproterenol results in increased expression of ABHD4 mRNA CTD PMID:20003209 NCBI chr15:27,697,384...27,716,013
Ensembl chr15:27,704,113...27,716,966 		JBrowse link
G Abi3 ABI family, member 3 increases expression ISO Isoproterenol results in increased expression of ABI3 mRNA CTD PMID:20003209 NCBI chr10:80,769,819...80,780,816
Ensembl chr10:80,769,822...80,780,816 		JBrowse link
G Ablim3 actin binding LIM protein family, member 3 increases expression ISO Isoproterenol results in increased expression of ABLIM3 mRNA CTD PMID:20003209 NCBI chr18:55,256,135...55,376,629
Ensembl chr18:55,257,583...55,376,380 		JBrowse link
G Acaca acetyl-CoA carboxylase alpha multiple interactions
decreases phosphorylation
increases phosphorylation		 ISO
EXP		 triacsin C inhibits the reaction [Isoproterenol results in increased phosphorylation of ACACA protein]
Isoproterenol results in decreased phosphorylation of ACACA protein		 CTD PMID:18390901 PMID:27491814 NCBI chr10:69,014,261...69,276,453
Ensembl chr10:69,014,170...69,276,457 		JBrowse link
G Acadl acyl-CoA dehydrogenase, long chain multiple interactions
decreases expression		 EXP [Isoproterenol co-treated with POSTN protein] results in decreased expression of ACADL mRNA; Sirolimus inhibits the reaction [Isoproterenol results in decreased expression of ACADL mRNA]; TNF protein inhibits the reaction [Sirolimus inhibits the reaction [Isoproterenol results in decreased expression of ACADL mRNA]] CTD PMID:25045214 PMID:30303030 NCBI chr 9:68,333,981...68,372,149
Ensembl chr 9:68,333,980...68,372,220 		JBrowse link
G Acadm acyl-CoA dehydrogenase medium chain decreases activity
multiple interactions
decreases expression		 EXP Isoproterenol results in decreased activity of ACADM protein
[Isoproterenol co-treated with POSTN protein] results in decreased expression of ACADM mRNA; Sirolimus inhibits the reaction [Isoproterenol results in decreased expression of ACADM mRNA]; TNF protein inhibits the reaction [Sirolimus inhibits the reaction [Isoproterenol results in decreased expression of ACADM mRNA]]		 CTD PMID:19826179 PMID:25045214 PMID:30303030 NCBI chr 2:242,858,865...242,883,036
Ensembl chr 2:242,858,865...242,883,147 		JBrowse link
G Acads acyl-CoA dehydrogenase short chain multiple interactions
decreases expression		 EXP [Isoproterenol co-treated with POSTN protein] results in decreased expression of ACADS mRNA
Isoproterenol results in decreased expression of ACADS mRNA		 CTD PMID:30303030 NCBI chr12:41,493,650...41,502,897
Ensembl chr12:41,493,626...41,502,898 		JBrowse link
G Acadvl acyl-CoA dehydrogenase, very long chain decreases expression
multiple interactions		 EXP Isoproterenol results in decreased expression of ACADVL mRNA
[Isoproterenol co-treated with POSTN protein] results in decreased expression of ACADVL mRNA		 CTD PMID:30303030 NCBI chr10:54,732,875...54,738,102
Ensembl chr10:54,732,469...54,738,075 		JBrowse link
G Ace angiotensin I converting enzyme multiple interactions
increases activity		 EXP oleuropein inhibits the reaction [Isoproterenol results in increased activity of ACE protein] CTD PMID:26056852 NCBI chr10:90,910,316...90,930,437
Ensembl chr10:90,910,316...90,931,131 		JBrowse link
G Ace2 angiotensin converting enzyme 2 increases expression
decreases activity
multiple interactions		 ISO
EXP		 Isoproterenol results in increased expression of ACE2 mRNA
Isoproterenol results in decreased activity of ACE2 protein
[Isoproterenol results in decreased activity of ACE2 protein] which results in decreased abundance of angiotensin I (1-7); xanthone inhibits the reaction [[Isoproterenol results in decreased activity of ACE2 protein] which results in decreased abundance of angiotensin I (1-7)]; xanthone inhibits the reaction [Isoproterenol results in decreased activity of ACE2 protein]
Isoproterenol results in increased expression of ACE2 protein		 CTD PMID:20003209 PMID:20409916 PMID:36414029 NCBI chr  X:30,293,597...30,340,961
Ensembl chr  X:30,293,589...30,340,977 		JBrowse link
G Acer2 alkaline ceramidase 2 increases expression ISO Isoproterenol results in increased expression of ACER2 mRNA CTD PMID:20003209 NCBI chr 5:101,391,830...101,442,615
Ensembl chr 5:101,391,885...101,442,614 		JBrowse link
G Acsl1 acyl-CoA synthetase long-chain family member 1 multiple interactions EXP [Isoproterenol co-treated with POSTN protein] results in decreased expression of ACSL1 mRNA CTD PMID:30303030 NCBI chr16:45,755,246...45,821,541
Ensembl chr16:45,755,254...45,821,541 		JBrowse link
G Acta1 actin, alpha 1, skeletal muscle multiple interactions ISO [Phenylephrine co-treated with Isoproterenol] results in increased expression of ACTA1 mRNA; EGR1 protein affects the reaction [[Phenylephrine co-treated with Isoproterenol] results in increased expression of ACTA1 mRNA] CTD PMID:10710348 NCBI chr19:51,883,709...51,886,735
Ensembl chr19:51,883,715...51,886,742 		JBrowse link
G Acta2 actin alpha 2, smooth muscle multiple interactions
increases expression
decreases expression		 ISO
EXP		 Doxycycline inhibits the reaction [Isoproterenol results in decreased expression of ACTA2 mRNA]
Glyburide promotes the reaction [Isoproterenol results in increased expression of ACTA2 protein]; pyrvinium inhibits the reaction [Glyburide promotes the reaction [Isoproterenol results in increased expression of ACTA2 protein]]; pyrvinium inhibits the reaction [Isoproterenol results in increased expression of ACTA2 protein]; xanthone inhibits the reaction [Isoproterenol results in increased expression of ACTA2 protein]
Isoproterenol results in increased expression of ACTA2 mRNA; Isoproterenol results in increased expression of ACTA2 protein		 CTD PMID:18089841 PMID:20003209 PMID:24945829 PMID:28526319 PMID:35305975 More... NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554 		JBrowse link
G Actb actin, beta decreases expression ISO Isoproterenol results in decreased expression of ACTB mRNA CTD PMID:20003209 NCBI chr12:11,663,112...11,666,697
Ensembl chr12:11,663,109...11,672,877 		JBrowse link
G Actg2 actin gamma 2, smooth muscle increases expression ISO Isoproterenol results in increased expression of ACTG2 mRNA CTD PMID:21335049 NCBI chr 4:116,021,832...116,046,475
Ensembl chr 4:116,021,832...116,046,465 		JBrowse link
G Ada adenosine deaminase multiple interactions
increases expression		 ISO Doxycycline inhibits the reaction [Isoproterenol results in increased expression of ADA mRNA] CTD PMID:18089841 PMID:20003209 NCBI chr 3:152,398,745...152,422,854
Ensembl chr 3:152,398,747...152,447,088 		JBrowse link
G Adam17 ADAM metallopeptidase domain 17 multiple interactions
increases expression		 EXP
ISO		 bellidifolin inhibits the reaction [Isoproterenol results in increased expression of ADAM17 mRNA] CTD PMID:37528096 NCBI chr 6:40,872,936...40,920,700
Ensembl chr 6:40,872,856...40,920,639 		JBrowse link
G Adam22 ADAM metallopeptidase domain 22 increases expression ISO Isoproterenol results in increased expression of ADAM22 mRNA CTD PMID:20003209 NCBI chr 4:25,716,055...25,970,932
Ensembl chr 4:25,715,990...25,964,962 		JBrowse link
G Adam8 ADAM metallopeptidase domain 8 increases expression EXP Isoproterenol results in increased expression of ADAM8 mRNA CTD PMID:20211217 NCBI chr 1:194,776,559...194,789,330
Ensembl chr 1:194,770,060...194,788,801 		JBrowse link
G Adamtsl2 ADAMTS-like 2 increases expression ISO Isoproterenol results in increased expression of ADAMTSL2 mRNA CTD PMID:20003209 NCBI chr 3:10,397,774...10,434,557
Ensembl chr 3:10,404,626...10,434,554 		JBrowse link
G Adamtsl4 ADAMTS-like 4 increases expression ISO Isoproterenol results in increased expression of ADAMTSL4 mRNA CTD PMID:20003209 NCBI chr 2:183,235,634...183,247,091
Ensembl chr 2:183,235,646...183,246,848 		JBrowse link
G Adcy5 adenylate cyclase 5 increases response to substance
multiple interactions		 ISO ADCY5 protein results in increased susceptibility to Isoproterenol
[ADCY5 protein results in increased susceptibility to Isoproterenol] which results in decreased expression of SOD2 protein; SOD2 protein inhibits the reaction [ADCY5 protein results in increased susceptibility to Isoproterenol]		 CTD PMID:12869393 PMID:23536361 NCBI chr11:65,471,612...65,618,877
Ensembl chr11:65,471,612...65,618,974 		JBrowse link
G Adcy6 adenylate cyclase 6 affects response to substance ISO ADCY6 protein affects the susceptibility to Isoproterenol CTD PMID:12393090 NCBI chr 7:129,742,827...129,763,922
Ensembl chr 7:129,742,838...129,763,754 		JBrowse link
G Adcy9 adenylate cyclase 9 multiple interactions ISO [Isoproterenol co-treated with Miconazole] results in increased activity of ADCY9 protein alternative form CTD PMID:30607468 NCBI chr10:11,138,966...11,262,067
Ensembl chr10:11,139,446...11,262,066 		JBrowse link
G Add3 adducin 3 decreases expression ISO Isoproterenol results in decreased expression of ADD3 mRNA CTD PMID:21335049 NCBI chr 1:252,147,341...252,255,126
Ensembl chr 1:252,147,386...252,255,124 		JBrowse link
G Adgrd1 adhesion G protein-coupled receptor D1 increases expression ISO Isoproterenol results in increased expression of ADGRD1 mRNA CTD PMID:20003209 NCBI chr12:27,488,908...27,603,714
Ensembl chr12:27,488,908...27,603,696 		JBrowse link
G Adgrf5 adhesion G protein-coupled receptor F5 increases expression ISO Isoproterenol results in increased expression of ADGRF5 mRNA CTD PMID:20003209 NCBI chr 9:17,517,596...17,624,107
Ensembl chr 9:17,520,009...17,623,968 		JBrowse link
G Adgrl4 adhesion G protein-coupled receptor L4 increases expression ISO Isoproterenol results in increased expression of ADGRL4 mRNA CTD PMID:20003209 NCBI chr 2:240,354,909...240,457,231
Ensembl chr 2:240,354,941...240,457,225 		JBrowse link
G Adh1c alcohol dehydrogenase 1C (class I), gamma polypeptide increases expression ISO Isoproterenol results in increased expression of ADH1 mRNA CTD PMID:20003209 NCBI chr 2:226,797,303...226,808,892
Ensembl chr 2:226,797,303...226,808,892 		JBrowse link
G Adm adrenomedullin multiple interactions
increases expression		 EXP [Phenylephrine co-treated with Isoproterenol] results in increased expression of ADM mRNA; [Phenylephrine co-treated with Isoproterenol] results in increased expression of ADM protein; ADM protein inhibits the reaction [Isoproterenol promotes the reaction [ADM protein results in increased abundance of Cyclic AMP]]; CALCA protein inhibits the reaction [Isoproterenol promotes the reaction [ADM protein results in increased abundance of Cyclic AMP]]; Isoproterenol promotes the reaction [ADM protein results in increased abundance of Cyclic AMP]
Isoproterenol results in increased expression of ADM mRNA; Isoproterenol results in increased expression of ADM protein		 CTD PMID:12732346 PMID:17250927 PMID:17306419 NCBI chr 1:164,745,484...164,747,655
Ensembl chr 1:164,745,466...164,747,654 		JBrowse link
G Adra1b adrenoceptor alpha 1B multiple interactions
decreases expression		 ISO ADRA1B protein affects the reaction [Isoproterenol results in increased abundance of Cyclic AMP]
Isoproterenol results in decreased expression of ADRA1B mRNA		 CTD PMID:12649302 PMID:20003209 NCBI chr10:28,255,025...28,373,418
Ensembl chr10:28,255,025...28,312,919 		JBrowse link
G Adrb1 adrenoceptor beta 1 multiple interactions
decreases expression
increases phosphorylation
increases activity
affects response to substance
increases uptake		 ISO
EXP		 [Isoproterenol binds to and results in increased activity of ADRB1 protein] which results in increased abundance of Cyclic AMP; Atenolol inhibits the reaction [Isoproterenol results in increased activity of ADRB1 protein]; carvedilol inhibits the reaction [Isoproterenol results in increased activity of ADRB1 protein]; CGP 12177 inhibits the reaction [Isoproterenol results in increased activity of ADRB1 protein]; CGP 20712A inhibits the reaction [Isoproterenol results in increased activity of ADRB1 protein]; Isoproterenol binds to and results in increased activity of ADRB1 protein; Isoproterenol inhibits the reaction [cyanopindolol binds to ADRB1 protein]; Isoproterenol inhibits the reaction [Iodocyanopindolol binds to ADRB1 protein]; Isoproterenol promotes the reaction [ADRB1 protein binds to ARRB1 protein]; Isoproterenol promotes the reaction [ADRB1 protein binds to ARRB2 protein]; Isoproterenol promotes the reaction [ADRB1 protein results in increased abundance of Cyclic AMP]; Isoproterenol promotes the reaction [ADRB1 protein results in increased uptake of EGFR protein]; Propranolol inhibits the reaction [Isoproterenol results in increased activity of ADRB1 protein]
Isoproterenol results in decreased expression of ADRB1 mRNA
Isoproterenol results in increased phosphorylation of ADRB1 protein
[ADRB3 affects the expression of ADRB1 mRNA] which affects the susceptibility to Isoproterenol
ADRB1 protein polymorphism affects the susceptibility to Isoproterenol
Isoproterenol results in increased uptake of ADRB1 protein
ADRB1 protein promotes the reaction [Isoproterenol results in decreased expression of NPPA protein]; ADRB1 protein promotes the reaction [Isoproterenol results in increased abundance of Cyclic AMP]; AGT affects the reaction [Isoproterenol results in decreased expression of ADRB1 mRNA]; Isoproterenol binds to and results in increased activity of ADRB1 protein; Isoproterenol inhibits the reaction [Iodocyanopindolol binds to ADRB1 protein]; Metoprolol inhibits the reaction [Isoproterenol results in decreased expression of ADRB1 mRNA]
Isoproterenol results in decreased expression of ADRB1; Isoproterenol results in decreased expression of ADRB1 mRNA		 CTD PMID:1312942 PMID:8096834 PMID:8723169 PMID:11159692 PMID:12761341 More... NCBI chr 1:255,771,962...255,774,973
Ensembl chr 1:255,771,597...255,807,259 		JBrowse link
G Adrb2 adrenoceptor beta 2 multiple interactions
increases activity
affects expression
increases uptake
decreases expression
increases phosphorylation
increases expression		 ISO
EXP		 4-(1H-imidazol-4-ylmethyl)piperidine promotes the reaction [Isoproterenol results in increased activity of ADRB2 protein]; [Isoproterenol binds to ADRB2 protein] which results in increased phosphorylation of MAPK1 protein; [Isoproterenol binds to ADRB2 protein] which results in increased phosphorylation of MAPK3 protein; [Isoproterenol binds to and results in increased activity of ADRB2 protein] which results in increased abundance of Cyclic AMP; [Isoproterenol binds to and results in increased activity of ADRB2 protein] which results in increased phosphorylation of and results in increased activity of MAPK1 protein; [Isoproterenol binds to and results in increased activity of ADRB2 protein] which results in increased phosphorylation of and results in increased activity of MAPK3 protein; [Isoproterenol results in increased activity of ADRB2 protein] which results in increased chemical synthesis of Cyclic AMP; [Terbutaline binds to and results in increased activity of ADRB2 protein] which results in decreased susceptibility to Isoproterenol; Atenolol inhibits the reaction [[Isoproterenol binds to and results in increased activity of ADRB2 protein] which results in increased abundance of Cyclic AMP]; Atenolol inhibits the reaction [Isoproterenol binds to and results in increased activity of ADRB2 protein]; clobenpropit promotes the reaction [Isoproterenol results in increased activity of ADRB2 protein]; Cobalt promotes the reaction [Isoproterenol binds to and results in increased activity of ADRB2 protein]; Histamine promotes the reaction [Isoproterenol results in increased activity of ADRB2 protein]; ICI 118551 inhibits the reaction [[Isoproterenol binds to and results in increased activity of ADRB2 protein] which results in increased abundance of Cyclic AMP]; ICI 118551 inhibits the reaction [Isoproterenol binds to and results in increased activity of ADRB2 protein]; ICI 118551 inhibits the reaction [Isoproterenol results in increased activity of ADRB2 protein]; imidazole promotes the reaction [Isoproterenol results in increased activity of ADRB2 protein]; Isoproterenol binds to and results in increased activity of ADRB2 protein; Isoproterenol inhibits the reaction [cyanopindolol binds to ADRB2 protein]; Isoproterenol promotes the reaction [ADRB2 protein binds to ARRB2 protein]; Ketotifen inhibits the reaction [[Terbutaline binds to and results in increased activity of ADRB2 protein] which results in decreased susceptibility to Isoproterenol]; Propranolol inhibits the reaction [[Isoproterenol binds to and results in increased activity of ADRB2 protein] which results in increased abundance of Cyclic AMP]; Propranolol inhibits the reaction [Isoproterenol binds to and results in increased activity of ADRB2 protein]; Zinc promotes the reaction [Isoproterenol binds to and results in increased activity of ADRB2 protein]
Isoproterenol affects the expression of ADRB2 mRNA
Isoproterenol results in increased uptake of ADRB2 protein
[Isoproterenol results in increased activity of ADRB2 protein] which results in increased secretion of Histamine; ADRB2 protein promotes the reaction [Isoproterenol results in increased abundance of Cyclic AMP]
Isoproterenol results in decreased expression of ADRB2; Isoproterenol results in decreased expression of ADRB2 mRNA
[GNA15 protein results in increased susceptibility to Isoproterenol] which results in increased activity of ADRB2 protein; ADRB2 protein affects the reaction [Isoproterenol results in increased expression of IL18 mRNA]; CAV1 protein promotes the reaction [Isoproterenol results in increased activity of ADRB2 protein]; ICI 118551 inhibits the reaction [Isoproterenol results in increased activity of ADRB2 protein]
Isoproterenol results in increased phosphorylation of ADRB2 protein
Isoproterenol results in increased expression of ADRB2 mRNA		 CTD PMID:9875846 PMID:10226872 PMID:10516654 PMID:11164953 PMID:11752207 More... NCBI chr18:55,642,459...55,644,501
Ensembl chr18:55,502,903...55,644,512 		JBrowse link
G Adrb3 adrenoceptor beta 3 multiple interactions
increases activity
increases expression		 ISO
EXP		 [Isoproterenol binds to and results in increased activity of ADRB3 protein] which results in increased abundance of Cyclic AMP; Isoproterenol binds to and results in increased activity of ADRB3 protein; Isoproterenol inhibits the reaction [cyanopindolol binds to ADRB3 protein]; L 748,337 inhibits the reaction [Isoproterenol results in increased activity of ADRB3 protein]
Isoproterenol results in increased expression of ADRB3 mRNA; Isoproterenol results in increased expression of ADRB3 protein
[ADRB3 affects the expression of ADRB1 mRNA] which affects the susceptibility to Isoproterenol
3-(2-ethylphenoxy)-1-(1,2,3,4-tetrahydronaphth-1-ylamino)-2-propanol oxalate inhibits the reaction [Isoproterenol results in increased activity of ADRB3 protein]; 3-(2-ethylphenoxy)-1-(1,2,3,4-tetrahydronaphth-1-ylamino)-2-propanol oxalate inhibits the reaction [Isoproterenol results in increased expression of ADRB3 protein]; BRL 37344 promotes the reaction [Isoproterenol results in increased expression of ADRB3 mRNA]; BRL 37344 promotes the reaction [Isoproterenol results in increased expression of ADRB3 protein]; Isoproterenol binds to and results in increased activity of ADRB3 protein		 CTD PMID:1682311 PMID:7815362 PMID:11159692 PMID:14730417 PMID:15009959 More... NCBI chr16:64,839,820...64,844,552
Ensembl chr16:64,841,788...64,844,552 		JBrowse link
G Aen apoptosis enhancing nuclease decreases expression ISO Isoproterenol results in decreased expression of AEN mRNA CTD PMID:20003209 NCBI chr 1:132,815,094...132,824,522
Ensembl chr 1:132,815,142...132,824,523 		JBrowse link
G Agbl5 AGBL carboxypeptidase 5 decreases expression ISO Isoproterenol results in decreased expression of AGBL5 mRNA CTD PMID:20003209 NCBI chr 6:25,472,333...25,492,173
Ensembl chr 6:25,472,333...25,490,738 		JBrowse link
G Agt angiotensinogen multiple interactions
increases expression		 ISO
EXP		 adenosine-3',5'-cyclic phosphorothioate inhibits the reaction [Isoproterenol promotes the reaction [Dexamethasone results in increased expression of AGT protein]]; ICI 118551 inhibits the reaction [Isoproterenol promotes the reaction [Dexamethasone results in increased expression of AGT protein]]; Isoproterenol promotes the reaction [Dexamethasone results in increased expression of AGT protein]; Propranolol inhibits the reaction [Isoproterenol promotes the reaction [Dexamethasone results in increased expression of AGT protein]]
Isoproterenol results in increased expression of AGT protein
AGT affects the reaction [Isoproterenol results in decreased expression of ADRB1 mRNA]; AGT affects the reaction [Isoproterenol results in decreased expression of GRK2 mRNA]; AGT inhibits the reaction [Isoproterenol results in increased expression of COL3A1 protein]; Isoproterenol inhibits the reaction [AGT protein results in increased phosphorylation of MAPK1 protein]; Isoproterenol inhibits the reaction [AGT protein results in increased phosphorylation of MAPK3 protein]; Losartan inhibits the reaction [Isoproterenol results in increased expression of AGT protein]; Losartan promotes the reaction [Isoproterenol results in increased expression of AGT protein]; natakalim inhibits the reaction [Isoproterenol results in increased expression of AGT protein]; Quercetin inhibits the reaction [Isoproterenol results in increased expression of AGT protein]; Quinapril inhibits the reaction [Isoproterenol results in increased expression of AGT protein]; Quinapril promotes the reaction [Isoproterenol results in increased expression of AGT protein]; Rutin inhibits the reaction [Isoproterenol results in increased expression of AGT protein]; trandolapril inhibits the reaction [Isoproterenol results in increased expression of AGT protein]; xanthone inhibits the reaction [Isoproterenol results in increased expression of AGT protein]
Isoproterenol results in increased expression of AGT mRNA; Isoproterenol results in increased expression of AGT protein
Propranolol inhibits the reaction [Isoproterenol results in increased expression of AGT protein]		 CTD PMID:1534315 PMID:1653766 PMID:7843740 PMID:11709406 PMID:16731636 More... NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977 		JBrowse link
G Agtr1a angiotensin II receptor, type 1a decreases expression ISO Isoproterenol results in decreased expression of AGTR1A mRNA CTD PMID:17350036 NCBI chr17:34,173,446...34,226,892
Ensembl chr17:34,174,429...34,226,946 		JBrowse link
G Ahcy adenosylhomocysteinase increases expression ISO Isoproterenol results in increased expression of AHCY mRNA CTD PMID:20003209 NCBI chr 3:143,569,134...143,584,359
Ensembl chr 3:143,569,094...143,584,393 		JBrowse link
G Ahnak2 AHNAK nucleoprotein 2 increases expression ISO Isoproterenol results in increased expression of AHNAK2 mRNA CTD PMID:20003209 NCBI chr 6:131,830,668...131,876,311
Ensembl chr 6:131,831,454...131,854,463 		JBrowse link
G Ahr aryl hydrocarbon receptor increases expression
decreases expression		 ISO
EXP		 Isoproterenol results in increased expression of AHR mRNA
Isoproterenol results in decreased expression of AHR mRNA		 CTD PMID:24286936 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568 		JBrowse link
G Ahsg alpha-2-HS-glycoprotein increases expression ISO Isoproterenol results in increased expression of AHSG mRNA CTD PMID:20003209 PMID:21335049 NCBI chr11:78,121,388...78,127,998
Ensembl chr11:78,117,918...78,145,999 		JBrowse link
G Aif1 allograft inflammatory factor 1 decreases expression ISO Isoproterenol results in decreased expression of AIF1 mRNA CTD PMID:20003209 NCBI chr20:3,646,784...3,652,670
Ensembl chr20:3,646,777...3,652,668 		JBrowse link
G Ak4 adenylate kinase 4 decreases expression ISO Isoproterenol results in decreased expression of AK4 mRNA CTD PMID:20003209 NCBI chr 5:116,039,222...116,099,064
Ensembl chr 5:116,039,616...116,098,618 		JBrowse link
G Akap1 A-kinase anchoring protein 1 decreases expression ISO Isoproterenol results in decreased expression of AKAP1 mRNA CTD PMID:20003209 NCBI chr10:73,621,021...73,654,123
Ensembl chr10:73,621,883...73,653,896 		JBrowse link
G Akap13 A-kinase anchoring protein 13 increases expression ISO Isoproterenol results in increased expression of AKAP13 mRNA CTD PMID:20003209 NCBI chr 1:129,313,183...129,619,647
Ensembl chr 1:129,314,402...129,619,646 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 increases phosphorylation
increases expression
increases activity
decreases phosphorylation
multiple interactions
decreases expression		 ISO
EXP		 Isoproterenol results in increased phosphorylation of AKT1 protein
Isoproterenol results in increased expression of AKT1 mRNA
Isoproterenol increases activity of Akt1 protein in adipocytes
Isoproterenol results in decreased phosphorylation of AKT1 protein
2-((2-piperidin-1-ylethyl)thio)quinazolin-4(3H)-one promotes the reaction [Isoproterenol results in increased phosphorylation of AKT1 protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Isoproterenol results in increased phosphorylation of AKT1 protein]; 5-Methoxypsoralen inhibits the reaction [Isoproterenol results in decreased phosphorylation of AKT1 protein]; [Isoproterenol co-treated with POSTN protein] results in decreased expression of AKT1 mRNA; [PDE3B protein co-treated with AKT1 protein] inhibits the reaction [Isoproterenol results in increased phosphorylation of PRKAA1 protein]; Enalapril promotes the reaction [Isoproterenol results in increased phosphorylation of AKT1 protein]; plantamajoside inhibits the reaction [Isoproterenol results in increased phosphorylation of AKT1 protein]; swietenine inhibits the reaction [Isoproterenol results in increased phosphorylation of AKT1 protein]; Valsartan inhibits the reaction [Isoproterenol results in increased phosphorylation of AKT1 protein]; zingiberene inhibits the reaction [Isoproterenol results in increased expression of AKT1 mRNA]
Isoproterenol results in decreased expression of AKT1 mRNA
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Isoproterenol results in increased phosphorylation of and results in increased activity of AKT1 protein]; Isoproterenol results in increased phosphorylation of and results in increased activity of AKT1 protein; plantamajoside inhibits the reaction [Isoproterenol results in increased phosphorylation of AKT1 protein]; swietenine inhibits the reaction [Isoproterenol results in increased phosphorylation of AKT1 protein]; Valsartan inhibits the reaction [Isoproterenol results in increased phosphorylation of AKT1 protein]; Wortmannin inhibits the reaction [Isoproterenol results in increased phosphorylation of and results in increased activity of AKT1 protein]		 CTD
RGD		 PMID:15178407 PMID:15618457 PMID:15951400 PMID:16716347 PMID:17623046 More... RGD:407420264 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Alb albumin increases secretion ISO Isoproterenol results in increased secretion of ALB protein CTD PMID:38369011 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836 		JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member decreases expression ISO Isoproterenol results in decreased expression of ALDH2 mRNA CTD PMID:20003209 NCBI chr12:34,949,549...34,982,527
Ensembl chr12:34,901,219...34,982,521 		JBrowse link
G Aldh3a2 aldehyde dehydrogenase 3 family, member A2 decreases expression ISO Isoproterenol results in decreased expression of ALDH3A2 mRNA CTD PMID:21335049 NCBI chr10:45,928,313...45,949,366
Ensembl chr10:45,908,524...45,949,281 		JBrowse link
G Alpk2 alpha-kinase 2 increases expression ISO Isoproterenol results in increased expression of ALPK2 mRNA CTD PMID:20003209 NCBI chr18:58,775,603...58,906,150
Ensembl chr18:58,775,605...58,906,258 		JBrowse link
G Alpk3 alpha-kinase 3 decreases expression
multiple interactions		 ISO Isoproterenol results in decreased expression of ALPK3 mRNA; Isoproterenol results in decreased expression of ALPK3 protein
MIR384 mRNA inhibits the reaction [Isoproterenol results in decreased expression of ALPK3 mRNA]		 CTD PMID:35510648 NCBI chr 1:135,014,455...135,062,294
Ensembl chr 1:135,014,499...135,062,302 		JBrowse link
G Alpp alkaline phosphatase, placental multiple interactions
increases expression		 ISO Amphetamine promotes the reaction [Isoproterenol results in increased expression of ALPP mRNA]; Chlorpromazine inhibits the reaction [Isoproterenol results in increased expression of ALPP mRNA]; Clozapine inhibits the reaction [Isoproterenol results in increased expression of ALPP mRNA]; Desipramine inhibits the reaction [Isoproterenol results in increased expression of ALPP mRNA]; ICI 118551 inhibits the reaction [Isoproterenol results in increased expression of ALPP mRNA]; norfluoxetine inhibits the reaction [Isoproterenol results in increased expression of ALPP mRNA] CTD PMID:16036225 NCBI chr 9:87,765,846...87,768,606
Ensembl chr 9:87,765,860...87,768,606 		JBrowse link
G Amy1 amylase alpha 1 multiple interactions EXP Atenolol inhibits the reaction [Isoproterenol results in increased secretion of and results in increased activity of AMY1A protein]; Isoproterenol results in increased secretion of and results in increased activity of AMY1A protein; Propranolol inhibits the reaction [Isoproterenol results in increased secretion of and results in increased activity of AMY1A protein] CTD PMID:21173550 NCBI chr 2:201,382,678...201,397,487
Ensembl chr 2:201,382,675...201,397,816 		JBrowse link
G Ang angiogenin increases expression
multiple interactions		 ISO Isoproterenol results in increased expression of ANG mRNA
Doxycycline inhibits the reaction [Isoproterenol results in increased expression of ANG mRNA]		 CTD PMID:18089841 PMID:20003209 NCBI chr15:24,312,711...24,323,361 JBrowse link
G Angpt2 angiopoietin 2 increases expression EXP Isoproterenol results in increased expression of ANGPT2 mRNA CTD PMID:22908232 NCBI chr16:71,088,364...71,138,805
Ensembl chr16:71,088,364...71,138,804 		JBrowse link
G Angptl2 angiopoietin-like 2 decreases expression ISO Isoproterenol results in decreased expression of ANGPTL2 mRNA CTD PMID:20003209 NCBI chr 3:16,517,185...16,547,024
Ensembl chr 3:16,517,420...16,548,178 		JBrowse link
G Angptl6 angiopoietin-like 6 decreases expression ISO Isoproterenol results in decreased expression of ANGPTL6 mRNA CTD PMID:21335049 NCBI chr 8:19,413,617...19,419,925
Ensembl chr 8:19,413,619...19,419,925 		JBrowse link
G Anp32a acidic nuclear phosphoprotein 32 family member A decreases expression ISO Isoproterenol results in decreased expression of ANP32A mRNA CTD PMID:20003209 PMID:21335049 NCBI chr 8:62,829,099...62,865,443
Ensembl chr 8:62,827,456...62,865,443 		JBrowse link
G Anxa1 annexin A1 multiple interactions
increases expression		 ISO ANXA1 affects the reaction [Isoproterenol results in decreased secretion of IL6 protein]
Isoproterenol results in increased expression of ANXA1 mRNA		 CTD PMID:16835395 PMID:20003209 NCBI chr 1:217,861,175...217,877,205
Ensembl chr 1:217,861,175...217,877,343 		JBrowse link
G Aoc1 amine oxidase, copper containing 1 multiple interactions
increases activity		 EXP Cycloheximide inhibits the reaction [Isoproterenol results in increased activity of AOC1 protein]; Dactinomycin inhibits the reaction [Isoproterenol results in increased activity of AOC1 protein]; H 35-25 inhibits the reaction [Isoproterenol results in increased activity of AOC1 protein]; pimagedine inhibits the reaction [Isoproterenol results in increased activity of AOC1 protein] CTD PMID:2860926 PMID:6218830 NCBI chr 4:77,812,260...77,831,846
Ensembl chr 4:77,812,260...77,831,840 		JBrowse link
G Aoc3 amine oxidase, copper containing 3 increases expression ISO Isoproterenol results in increased expression of AOC3 mRNA CTD PMID:20003209 NCBI chr10:86,272,757...86,280,702 JBrowse link
G Aox1 aldehyde oxidase 1 increases expression ISO Isoproterenol results in increased expression of AOX1 mRNA CTD PMID:20003209 NCBI chr 9:59,579,621...59,658,772
Ensembl chr 9:59,579,649...59,658,770 		JBrowse link
G Ap1b1 adaptor related protein complex 1 subunit beta 1 increases expression ISO Isoproterenol results in increased expression of AP1B1 mRNA CTD PMID:21335049 NCBI chr14:79,879,482...79,930,778
Ensembl chr14:79,879,533...79,930,778 		JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 increases expression ISO Isoproterenol results in increased expression of APAF1 mRNA CTD PMID:24286936 NCBI chr 7:25,494,143...25,579,540
Ensembl chr 7:25,494,609...25,579,540 		JBrowse link
G Apex1 apurinic/apyrimidinic endodeoxyribonuclease 1 increases expression ISO Isoproterenol results in increased expression of APEX1 mRNA CTD PMID:21335049 NCBI chr15:24,144,595...24,146,785
Ensembl chr15:24,144,362...24,146,785 		JBrowse link
G Apln apelin multiple interactions
decreases expression		 EXP Plant Extracts inhibits the reaction [Isoproterenol results in decreased expression of APLN mRNA]; Plant Extracts inhibits the reaction [Isoproterenol results in decreased expression of APLN protein]
Isoproterenol results in decreased expression of APLN mRNA; Isoproterenol results in decreased expression of APLN protein		 CTD PMID:19960946 NCBI chr  X:127,180,801...127,213,567
Ensembl chr  X:127,203,823...127,213,391 		JBrowse link
G Apoa2 apolipoprotein A2 increases expression ISO Isoproterenol results in increased expression of APOA2 mRNA CTD PMID:21335049 NCBI chr13:83,644,460...83,646,358
Ensembl chr13:83,644,470...83,646,355 		JBrowse link
G Apod apolipoprotein D increases expression ISO Isoproterenol results in increased expression of APOD mRNA CTD PMID:20003209 NCBI chr11:69,431,261...69,452,306
Ensembl chr11:69,431,260...69,452,305 		JBrowse link
G Appbp2 amyloid beta precursor protein binding protein 2 increases expression ISO Isoproterenol results in increased expression of APPBP2 mRNA CTD PMID:20003209 NCBI chr10:70,057,774...70,099,877
Ensembl chr10:70,057,774...70,099,835 		JBrowse link
G Appl2 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2 increases expression ISO Isoproterenol results in increased expression of APPL2 mRNA CTD PMID:20003209 NCBI chr 7:20,135,248...20,184,757
Ensembl chr 7:20,135,375...20,184,754 		JBrowse link
G Arf2 ADP-ribosylation factor 2 decreases expression ISO Isoproterenol results in decreased expression of ARF2 mRNA CTD PMID:20003209 NCBI chr10:88,867,836...88,889,654
Ensembl chr10:88,867,836...88,889,659 		JBrowse link
G Arf4 ARF GTPase 4 increases expression ISO Isoproterenol results in increased expression of ARF4 mRNA CTD PMID:21335049 NCBI chr16:1,896,692...1,913,267
Ensembl chr16:1,896,546...1,913,261 		JBrowse link
G Arhgap12 Rho GTPase activating protein 12 increases expression ISO Isoproterenol results in increased expression of ARHGAP12 mRNA CTD PMID:20003209 NCBI chr17:51,588,810...51,702,417
Ensembl chr17:51,588,842...51,702,080 		JBrowse link
G Arhgap18 Rho GTPase activating protein 18 decreases expression ISO Isoproterenol results in decreased expression of ARHGAP18 mRNA CTD PMID:20003209 NCBI chr 1:18,403,531...18,637,306
Ensembl chr 1:18,403,537...18,637,256 		JBrowse link
G Arhgap20 Rho GTPase activating protein 20 increases expression ISO Isoproterenol results in increased expression of ARHGAP20 mRNA CTD PMID:20003209 NCBI chr 8:52,074,472...52,155,739
Ensembl chr 8:52,074,158...52,155,739 		JBrowse link
G Arhgap24 Rho GTPase activating protein 24 increases expression ISO Isoproterenol results in increased expression of ARHGAP24 mRNA CTD PMID:20003209 NCBI chr14:6,800,624...7,183,877
Ensembl chr14:6,800,631...7,183,823 		JBrowse link
G Arhgdib Rho GDP dissociation inhibitor beta increases expression EXP Isoproterenol results in increased expression of ARHGDIB mRNA CTD PMID:30303030 NCBI chr 4:169,822,951...169,841,884
Ensembl chr 4:169,822,952...169,841,658 		JBrowse link
G Arid4b AT-rich interaction domain 4B increases expression ISO Isoproterenol results in increased expression of ARID4B mRNA CTD PMID:20003209 NCBI chr17:51,138,419...51,262,894
Ensembl chr17:51,138,535...51,262,906 		JBrowse link
G Arid5b AT-rich interaction domain 5B increases expression ISO Isoproterenol results in increased expression of ARID5B mRNA CTD PMID:20003209 NCBI chr20:20,307,731...20,490,746
Ensembl chr20:20,307,731...20,487,433 		JBrowse link
G Arl4a ARF like GTPase 4A increases expression ISO Isoproterenol results in increased expression of ARL4A mRNA CTD PMID:20003209 NCBI chr 6:57,079,496...57,084,156
Ensembl chr 6:57,078,812...57,085,066 		JBrowse link
G Arnt2 aryl hydrocarbon receptor nuclear translocator 2 decreases expression
increases expression		 ISO
EXP		 Isoproterenol results in decreased expression of ARNT2 mRNA
Isoproterenol results in increased expression of ARNT2 mRNA		 CTD PMID:24286936 NCBI chr 1:138,236,235...138,392,868
Ensembl chr 1:138,189,940...138,393,153 		JBrowse link
G Arrb1 arrestin, beta 1 multiple interactions ISO Isoproterenol promotes the reaction [ADRB1 protein binds to ARRB1 protein] CTD PMID:18787115 NCBI chr 1:153,837,964...153,912,111
Ensembl chr 1:153,838,078...153,904,061 		JBrowse link
G Arrb2 arrestin, beta 2 affects localization
multiple interactions		 ISO
EXP		 Isoproterenol affects the localization of ARRB2 protein
ARRB2 protein promotes the reaction [Isoproterenol results in increased phosphorylation of MAPK1 protein]; ARRB2 protein promotes the reaction [Isoproterenol results in increased phosphorylation of MAPK3 protein]; Isoproterenol promotes the reaction [ADRB1 protein binds to ARRB2 protein]; Isoproterenol promotes the reaction [ADRB2 protein binds to ARRB2 protein]; S-nitrosocysteine inhibits the reaction [Isoproterenol affects the localization of ARRB2 protein]		 CTD PMID:17482545 PMID:17925438 PMID:18787115 PMID:21078978 NCBI chr10:55,146,887...55,154,854
Ensembl chr10:55,146,818...55,154,850 		JBrowse link
G Arrdc2 arrestin domain containing 2 increases expression ISO Isoproterenol results in increased expression of ARRDC2 mRNA CTD PMID:20003209 NCBI chr16:18,601,897...18,606,029
Ensembl chr16:18,601,897...18,606,029 		JBrowse link
G Arrdc3 arrestin domain containing 3 increases expression ISO Isoproterenol results in increased expression of ARRDC3 mRNA CTD PMID:20003209 NCBI chr 2:11,137,464...11,149,978
Ensembl chr 2:11,137,460...11,149,978 		JBrowse link
G Asap1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 decreases expression ISO Isoproterenol results in decreased expression of ASAP1 mRNA CTD PMID:20003209 NCBI chr 7:95,786,130...96,093,111
Ensembl chr 7:95,787,818...96,092,754 		JBrowse link
G Asb11 ankyrin repeat and SOCS box containing 11 increases expression ISO Isoproterenol results in increased expression of ASB11 mRNA CTD PMID:20003209 NCBI chr  X:30,014,485...30,037,808
Ensembl chr  X:29,992,416...30,037,807 		JBrowse link
G Ascc3 activating signal cointegrator 1 complex subunit 3 increases expression ISO Isoproterenol results in increased expression of ASCC3 mRNA CTD PMID:20003209 NCBI chr20:53,510,137...53,795,446
Ensembl chr20:53,510,184...53,790,165 		JBrowse link
G Asns asparagine synthetase (glutamine-hydrolyzing) increases expression ISO Isoproterenol results in increased expression of ASNS mRNA CTD PMID:21335049 PMID:21823215 NCBI chr 4:35,784,995...35,803,474
Ensembl chr 4:35,785,237...35,803,423 		JBrowse link
G Asph aspartate-beta-hydroxylase decreases expression ISO Isoproterenol results in decreased expression of ASPH mRNA CTD PMID:20003209 NCBI chr 5:22,601,581...22,814,107
Ensembl chr 5:22,603,486...22,813,876 		JBrowse link
G Aspn asporin increases expression ISO Isoproterenol results in increased expression of ASPN mRNA CTD PMID:20003209 NCBI chr17:15,079,910...15,104,369
Ensembl chr17:15,080,639...15,104,041 		JBrowse link
G Atad2 ATPase family, AAA domain containing 2 increases expression ISO Isoproterenol results in increased expression of ATAD2 mRNA CTD PMID:20003209 NCBI chr 7:89,634,123...89,676,738
Ensembl chr 7:89,634,123...89,676,738 		JBrowse link
G Atf2 activating transcription factor 2 multiple interactions
increases phosphorylation		 ISO Doxycycline inhibits the reaction [Isoproterenol results in increased phosphorylation of ATF2 protein] CTD PMID:18089841 NCBI chr 3:58,718,323...58,795,280
Ensembl chr 3:58,718,332...58,795,236 		JBrowse link
G Atf3 activating transcription factor 3 increases expression
multiple interactions		 ISO
EXP		 Isoproterenol results in increased expression of ATF3 mRNA
Isoproterenol results in increased expression of ATF3 protein
N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Isoproterenol results in increased expression of ATF3 protein]		 CTD PMID:21823215 PMID:25136830 NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631 		JBrowse link
G Atp10d ATPase phospholipid transporting 10D (putative) increases expression ISO Isoproterenol results in increased expression of ATP10D mRNA CTD PMID:20003209 NCBI chr14:35,911,728...36,012,549
Ensembl chr14:35,912,141...36,012,564 		JBrowse link
G Atp2a2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 multiple interactions
decreases expression		 EXP astragaloside A inhibits the reaction [Isoproterenol results in decreased expression of and results in decreased activity of ATP2A2 protein]; astragaloside A inhibits the reaction [Isoproterenol results in decreased expression of ATP2A2 mRNA]; candesartan inhibits the reaction [Isoproterenol results in decreased expression of ATP2A2 protein]; Isoproterenol results in decreased expression of and results in decreased activity of ATP2A2 protein
Isoproterenol results in decreased expression of ATP2A2 mRNA; Isoproterenol results in decreased expression of ATP2A2 protein		 CTD PMID:16723803 PMID:17509559 NCBI chr12:34,072,710...34,122,142
Ensembl chr12:34,072,683...34,122,101 		JBrowse link
G Atp5f1a ATP synthase F1 subunit alpha multiple interactions
decreases expression		 EXP
ISO		 [Isoproterenol co-treated with POSTN protein] results in decreased expression of ATP5F1A mRNA
Isoproterenol results in decreased expression of ATP5F1A mRNA		 CTD PMID:20003209 PMID:30303030 NCBI chr18:71,292,406...71,300,342
Ensembl chr18:71,292,374...71,300,794 		JBrowse link
G Atp5f1d ATP synthase F1 subunit delta multiple interactions EXP [Isoproterenol co-treated with POSTN protein] results in decreased expression of ATP5F1D mRNA CTD PMID:30303030 NCBI chr 7:9,560,604...9,565,919
Ensembl chr 7:9,560,608...9,565,929 		JBrowse link
G Atp5mc1 ATP synthase membrane subunit c locus 1 multiple interactions EXP [Isoproterenol co-treated with POSTN protein] results in decreased expression of ATP5MC1 mRNA CTD PMID:30303030 NCBI chr10:81,024,056...81,026,780
Ensembl chr10:81,023,925...81,027,124
Ensembl chr10:81,023,925...81,027,124 		JBrowse link
G Atp5me ATP synthase membrane subunit e multiple interactions EXP [Isoproterenol co-treated with POSTN protein] results in increased expression of ATP5ME mRNA CTD PMID:30303030 NCBI chr14:1,319,868...1,320,996
Ensembl chr14:1,319,868...1,321,013 		JBrowse link
G Atp5pd ATP synthase peripheral stalk subunit d multiple interactions EXP [Isoproterenol co-treated with POSTN protein] results in increased expression of ATP5PD mRNA CTD PMID:30303030 NCBI chr10:100,657,700...100,662,960
Ensembl chr10:100,657,708...100,663,479 		JBrowse link
G Atp5po ATP synthase peripheral stalk subunit OSCP multiple interactions EXP [Isoproterenol co-treated with POSTN protein] results in decreased expression of ATP5PO mRNA CTD PMID:30303030 NCBI chr11:31,165,218...31,171,530
Ensembl chr11:31,165,217...31,171,592 		JBrowse link
G Atp6ap2 ATPase H+ transporting accessory protein 2 multiple interactions EXP [Isoproterenol co-treated with POSTN protein] results in decreased expression of ATP6AP2 mRNA CTD PMID:30303030 NCBI chr  X:10,183,983...10,210,948
Ensembl chr  X:10,183,068...10,210,918 		JBrowse link
G Atp6v1e1 ATPase H+ transporting V1 subunit E1 decreases expression ISO Isoproterenol results in decreased expression of ATP6V1E1 mRNA CTD PMID:20003209 NCBI chr 4:154,022,358...154,044,486
Ensembl chr 4:154,022,358...154,044,584 		JBrowse link
G Atp8b1 ATPase phospholipid transporting 8B1 increases expression ISO Isoproterenol results in increased expression of ATP8B1 mRNA CTD PMID:20003209 NCBI chr18:58,016,382...58,157,213
Ensembl chr18:58,018,268...58,157,396 		JBrowse link
G Atxn10 ataxin 10 increases expression ISO Isoproterenol results in increased expression of ATXN10 mRNA CTD PMID:20003209 NCBI chr 7:116,441,768...116,565,093
Ensembl chr 7:116,441,613...116,565,087 		JBrowse link
G Auts2 activator of transcription and developmental regulator AUTS2 decreases expression ISO Isoproterenol results in decreased expression of AUTS2 mRNA CTD PMID:20003209 NCBI chr12:24,104,187...25,194,123
Ensembl chr12:24,104,192...25,194,416 		JBrowse link
G Azi2 5-azacytidine induced 2 multiple interactions EXP [Isoproterenol co-treated with POSTN protein] results in decreased expression of AZI2 mRNA CTD PMID:30303030 NCBI chr 8:117,773,248...117,797,844
Ensembl chr 8:117,773,279...117,797,847 		JBrowse link
G Bag1 BAG cochaperone 1 decreases expression ISO Isoproterenol results in decreased expression of BAG1 mRNA CTD PMID:21335049 NCBI chr 5:56,068,494...56,081,075
Ensembl chr 5:56,068,494...56,081,075 		JBrowse link
G Bag4 BAG cochaperone 4 multiple interactions EXP [Isoproterenol co-treated with POSTN protein] results in decreased expression of BAG4 mRNA CTD PMID:30303030 NCBI chr16:66,288,678...66,305,893
Ensembl chr16:66,288,678...66,308,663 		JBrowse link
G Bak1 BCL2-antagonist/killer 1 decreases expression ISO Isoproterenol results in decreased expression of BAK1 mRNA CTD PMID:24286936 NCBI chr20:5,100,480...5,109,669
Ensembl chr20:5,100,480...5,109,264 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression
multiple interactions
decreases expression		 ISO
EXP		 Isoproterenol results in increased expression of BAX protein
2-chloro-5-nitrobenzanilide promotes the reaction [[Streptozocin co-treated with Isoproterenol] affects the expression of BAX protein]; [Acrolein results in increased susceptibility to Isoproterenol] which results in increased expression of BAX protein; [Streptozocin co-treated with Isoproterenol] affects the expression of BAX protein; Acrolein promotes the reaction [Isoproterenol results in increased expression of BAX mRNA]; Acrolein promotes the reaction [Isoproterenol results in increased expression of BAX protein]; anethole inhibits the reaction [Isoproterenol results in increased expression of BAX mRNA]; Apigenin inhibits the reaction [Isoproterenol results in increased expression of BAX protein]; erdosteine inhibits the reaction [Isoproterenol results in increased expression of BAX protein]; Hesperidin inhibits the reaction [2-chloro-5-nitrobenzanilide promotes the reaction [[Streptozocin co-treated with Isoproterenol] affects the expression of BAX protein]]; Hesperidin inhibits the reaction [[Streptozocin co-treated with Isoproterenol] affects the expression of BAX protein]; Plant Extracts inhibits the reaction [[Acrolein results in increased susceptibility to Isoproterenol] which results in increased expression of BAX protein]; Plant Extracts inhibits the reaction [Acrolein promotes the reaction [Isoproterenol results in increased expression of BAX mRNA]]; Plant Extracts inhibits the reaction [Acrolein promotes the reaction [Isoproterenol results in increased expression of BAX protein]]; protocatechuic acid inhibits the reaction [Isoproterenol results in increased expression of BAX protein]; punicalagin inhibits the reaction [Isoproterenol results in increased expression of BAX protein]; Rosuvastatin Calcium inhibits the reaction [Isoproterenol results in increased expression of BAX mRNA]; Tretinoin inhibits the reaction [Isoproterenol results in increased expression of BAX mRNA]; zingiberene inhibits the reaction [Isoproterenol results in increased expression of BAX protein]
Isoproterenol results in decreased expression of BAX mRNA
Isoproterenol results in increased expression of BAX mRNA; Isoproterenol results in increased expression of BAX protein		 CTD PMID:15052282 PMID:16116328 PMID:17961425 PMID:24286936 PMID:24954035 More... NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bcat1 branched chain amino acid transaminase 1 increases expression EXP Isoproterenol results in increased expression of BCAT1 mRNA CTD PMID:20211217 PMID:23558518 PMID:24286936 NCBI chr 4:177,964,834...178,046,573
Ensembl chr 4:177,964,834...178,046,597 		JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression
multiple interactions
increases expression		 ISO
EXP		 Isoproterenol results in decreased expression of BCL2 protein
2-chloro-5-nitrobenzanilide promotes the reaction [[Streptozocin co-treated with Isoproterenol] affects the expression of BCL2 protein]; [Acrolein results in increased susceptibility to Isoproterenol] which results in decreased expression of BCL2 protein; [erdosteine co-treated with Isoproterenol] affects the expression of BCL2 protein; [Isoproterenol co-treated with POSTN protein] results in increased expression of BCL2 mRNA; [Streptozocin co-treated with Isoproterenol] affects the expression of BCL2 protein; Acrolein promotes the reaction [Isoproterenol results in decreased expression of BCL2 mRNA]; anethole inhibits the reaction [Isoproterenol results in increased expression of BCL2 mRNA]; Apigenin inhibits the reaction [Isoproterenol results in decreased expression of BCL2 protein]; echinocystic acid affects the reaction [Isoproterenol affects the expression of BCL2 mRNA]; Enalapril inhibits the reaction [Isoproterenol results in decreased expression of BCL2 protein]; Hesperidin inhibits the reaction [2-chloro-5-nitrobenzanilide promotes the reaction [[Streptozocin co-treated with Isoproterenol] affects the expression of BCL2 protein]]; Hesperidin inhibits the reaction [[Streptozocin co-treated with Isoproterenol] affects the expression of BCL2 protein]; Hesperidin inhibits the reaction [Isoproterenol results in decreased expression of BCL2 protein]; Plant Extracts inhibits the reaction [[Acrolein results in increased susceptibility to Isoproterenol] which results in decreased expression of BCL2 protein]; Plant Extracts inhibits the reaction [Acrolein promotes the reaction [Isoproterenol results in decreased expression of BCL2 mRNA]]; protocatechuic acid inhibits the reaction [Isoproterenol results in decreased expression of BCL2 protein]; punicalagin inhibits the reaction [Isoproterenol results in decreased expression of BCL2 protein]; zingiberene inhibits the reaction [Isoproterenol results in decreased expression of BCL2 protein]
Isoproterenol results in decreased expression of BCL2 mRNA; Isoproterenol results in decreased expression of BCL2 protein		 CTD PMID:11218852 PMID:12791704 PMID:15052282 PMID:19573579 PMID:24954035 More... NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Bcl2l1 Bcl2-like 1 increases expression
decreases expression
multiple interactions		 ISO
EXP		 Isoproterenol results in increased expression of BCL2L1 mRNA
Isoproterenol results in decreased expression of BCL2L1 mRNA; Isoproterenol results in decreased expression of BCL2L1 protein
Isoproterenol results in increased expression of BCL2L1 mRNA alternative form; Isoproterenol results in increased expression of BCL2L1 protein; Isoproterenol results in increased expression of BCL2L1 protein alternative form
Apigenin inhibits the reaction [Isoproterenol results in decreased expression of BCL2L1 protein]; CGP 20712A inhibits the reaction [Isoproterenol results in increased expression of BCL2L1 protein]; geraniol inhibits the reaction [Isoproterenol results in decreased expression of BCL2L1 mRNA]; Metoprolol inhibits the reaction [Isoproterenol results in increased expression of BCL2L1 protein]; Perindopril inhibits the reaction [Isoproterenol results in increased expression of BCL2L1 mRNA alternative form]; Thymol inhibits the reaction [Isoproterenol results in decreased expression of BCL2L1 mRNA]		 CTD PMID:12738230 PMID:16116328 PMID:20003209 PMID:24286936 PMID:26996544 More... NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
Ensembl chr 1:141,253,523...141,303,479 		JBrowse link
G Bcl2l11 Bcl2-like 11 increases expression ISO
EXP		 Isoproterenol results in increased expression of BCL2L11 protein
Isoproterenol results in increased expression of BCL2L11 mRNA		 CTD PMID:14996839 PMID:24286936 NCBI chr 3:115,366,783...115,404,068
Ensembl chr 3:115,366,646...115,404,068 		JBrowse link
G Bdh1 3-hydroxybutyrate dehydrogenase 1 increases expression ISO Isoproterenol results in increased expression of BDH1 mRNA CTD PMID:20003209 NCBI chr11:69,302,534...69,343,173
Ensembl chr11:69,302,534...69,337,671 		JBrowse link
G Bicd1 BICD cargo adaptor 1 increases expression ISO Isoproterenol results in increased expression of BICD1 mRNA CTD PMID:20003209 NCBI chr 4:182,479,071...182,631,504
Ensembl chr 4:182,479,071...182,627,434 		JBrowse link
G Birc2 baculoviral IAP repeat-containing 2 multiple interactions EXP [Isoproterenol co-treated with POSTN protein] results in decreased expression of BIRC2 mRNA CTD PMID:30303030 NCBI chr 8:4,968,856...4,989,325
Ensembl chr 8:4,968,842...4,988,732 		JBrowse link
G Bmal1 basic helix-loop-helix ARNT like 1 increases expression ISO Isoproterenol results in increased expression of BMAL1 mRNA CTD PMID:20003209 NCBI chr 1:167,331,756...167,430,235
Ensembl chr 1:167,331,633...167,430,231 		JBrowse link
G Bmf Bcl2 modifying factor increases expression EXP Isoproterenol results in increased expression of BMF mRNA CTD PMID:24286936 NCBI chr 3:105,499,534...105,520,159
Ensembl chr 3:105,499,538...105,520,145 		JBrowse link
G Bmp10 bone morphogenetic protein 10 multiple interactions
decreases response to substance		 ISO BMP10 protein inhibits the reaction [Isoproterenol results in increased expression of CASP3 protein]; STAT3 protein affects the reaction [BMP10 protein results in decreased susceptibility to Isoproterenol]
BMP10 protein inhibits the reaction [Isoproterenol results in increased cleavage of PARP1 protein]; BMP10 protein inhibits the reaction [Isoproterenol results in increased expression of CASP3 protein]; BMP10 protein inhibits the reaction [Isoproterenol results in increased expression of COL1A1 protein]; BMP10 protein inhibits the reaction [Isoproterenol results in increased expression of COL3A1 protein]; STAT3 protein affects the reaction [BMP10 protein inhibits the reaction [Isoproterenol results in increased expression of CASP3 protein]]		 CTD PMID:31712309 NCBI chr 4:119,872,066...119,877,694
Ensembl chr 4:119,872,045...119,878,627 		JBrowse link
G Bmp2 bone morphogenetic protein 2 increases expression EXP isoprenaline increases expression of mRNA in neonatal rat cardiomyocytes RGD PMID:26873969 RGD:11526363 NCBI chr 3:120,812,660...120,822,579
Ensembl chr 3:120,812,882...120,821,397 		JBrowse link
G Bmp4 bone morphogenetic protein 4 increases expression EXP isoprenaline increases expression of mRNA in neonatal rat cardiomyocytes RGD PMID:26873969 RGD:11526363 NCBI chr15:19,618,538...19,633,494
Ensembl chr15:19,618,542...19,623,306 		JBrowse link
G Bmp7 bone morphogenetic protein 7 increases expression EXP isoprenaline increases expression of mRNA in neonatal rat cardiomyocytes RGD PMID:26873969 RGD:11526363 NCBI chr 3:161,639,915...161,716,938
Ensembl chr 3:161,516,462...161,716,788 		JBrowse link
G Bnip1 BCL2 interacting protein 1 increases expression ISO Isoproterenol results in increased expression of BNIP1 protein CTD PMID:15052282 NCBI chr10:16,386,876...16,399,124
Ensembl chr10:16,386,841...16,399,157 		JBrowse link
G Bnip3 BCL2 interacting protein 3 increases expression ISO Isoproterenol results in increased expression of BNIP3 mRNA CTD PMID:20003209 NCBI chr 1:193,708,164...193,725,348
Ensembl chr 1:193,708,167...193,725,359 		JBrowse link
G Bok BCL2 family apoptosis regulator BOK decreases expression ISO Isoproterenol results in decreased expression of BOK mRNA CTD PMID:21335049 NCBI chr 9:94,223,493...94,234,476
Ensembl chr 9:94,223,389...94,234,476 		JBrowse link
G Brd4 bromodomain containing 4 decreases expression
increases expression
multiple interactions		 ISO Isoproterenol results in decreased expression of BRD4 mRNA
Isoproterenol results in increased expression of BRD4 mRNA; Isoproterenol results in increased expression of BRD4 protein
bellidifolin inhibits the reaction [Isoproterenol results in increased expression of BRD4 mRNA]; bellidifolin inhibits the reaction [Isoproterenol results in increased expression of BRD4 protein]		 CTD PMID:20003209 PMID:37528096 NCBI chr 7:11,216,446...11,296,029
Ensembl chr 7:11,216,446...11,295,539 		JBrowse link
G Brwd1 bromodomain and WD repeat domain containing 1 increases expression ISO Isoproterenol results in increased expression of BRWD1 mRNA CTD PMID:20003209 NCBI chr11:35,286,364...35,378,768
Ensembl chr11:35,288,313...35,378,768 		JBrowse link
G Bsdc1 BSD domain containing 1 increases expression ISO Isoproterenol results in increased expression of BSDC1 mRNA CTD PMID:20003209 NCBI chr 5:141,798,918...141,827,091
Ensembl chr 5:141,798,981...141,827,092 		JBrowse link
G C3 complement C3 increases expression
multiple interactions
decreases expression		 ISO
EXP		 Isoproterenol results in increased expression of C3 mRNA
Acetylcysteine inhibits the reaction [Isoproterenol results in increased expression of C3 protein]; pifithrin inhibits the reaction [Isoproterenol results in increased expression of C3 protein]; S100A9 protein affects the reaction [Isoproterenol results in increased expression of C3 protein]
Isoproterenol results in decreased expression of C3 mRNA
Isoproterenol results in increased expression of C3 mRNA; Isoproterenol results in increased expression of C3 protein		 CTD PMID:20003209 PMID:24286936 PMID:32924446 NCBI chr 9:2,087,437...2,114,366
Ensembl chr 9:2,087,437...2,114,429 		JBrowse link
G C4b complement C4B increases expression ISO Isoproterenol results in increased expression of C4B mRNA CTD PMID:20003209 NCBI chr20:4,197,371...4,211,684
Ensembl chr20:4,197,366...4,211,681 		JBrowse link
G C5 complement C5 increases expression
multiple interactions		 EXP Isoproterenol results in increased expression of C5 protein
Acetylcysteine inhibits the reaction [Isoproterenol results in increased expression of C5 protein]; pifithrin inhibits the reaction [Isoproterenol results in increased expression of C5 protein]; S100A9 protein affects the reaction [Isoproterenol results in increased expression of C5 protein]		 CTD PMID:32924446 NCBI chr 3:18,270,696...18,361,994
Ensembl chr 3:18,270,696...18,361,994 		JBrowse link
G C9 complement C9 increases expression EXP Isoproterenol results in increased expression of C9 mRNA CTD PMID:24286936 NCBI chr 2:55,573,094...55,621,345
Ensembl chr 2:55,572,992...55,621,338 		JBrowse link
G Cacna1c calcium voltage-gated channel subunit alpha1 C increases expression EXP Isoproterenol results in increased expression of CACNA1C mRNA CTD PMID:17526999 NCBI chr 4:151,764,138...152,379,454
Ensembl chr 4:151,764,138...152,379,648 		JBrowse link
G Cadm4 cell adhesion molecule 4 decreases expression ISO Isoproterenol results in decreased expression of CADM4 mRNA CTD PMID:20003209 NCBI chr 1:80,075,163...80,097,423
Ensembl chr 1:80,075,202...80,097,423 		JBrowse link
G Calca calcitonin-related polypeptide alpha multiple interactions EXP CALCA protein inhibits the reaction [Isoproterenol promotes the reaction [ADM protein results in increased abundance of Cyclic AMP]] CTD PMID:17306419 NCBI chr 1:168,878,212...168,883,176
Ensembl chr 1:168,878,214...168,883,105 		JBrowse link
G Calcrl calcitonin receptor like receptor multiple interactions
increases expression		 EXP [Phenylephrine co-treated with Isoproterenol] results in increased expression of CALCRL mRNA
Isoproterenol results in increased expression of CALCRL mRNA; Isoproterenol results in increased expression of CALCRL protein		 CTD PMID:16987513 PMID:17250927 PMID:17306419 NCBI chr 3:69,428,348...69,525,910
Ensembl chr 3:69,430,120...69,525,910 		JBrowse link
G Calm3 calmodulin 3 decreases expression ISO Isoproterenol results in decreased expression of CALM3 mRNA CTD PMID:20003209 NCBI chr 1:77,590,668...77,597,776
Ensembl chr 1:77,589,230...77,592,207 		JBrowse link
G Calr calreticulin increases expression ISO Isoproterenol results in increased expression of CALR mRNA CTD PMID:21823215 NCBI chr19:23,308,525...23,313,420
Ensembl chr19:23,308,351...23,313,414 		JBrowse link
G Calr3 calreticulin 3 increases expression ISO Isoproterenol results in increased expression of CALR3 mRNA CTD PMID:20003209 NCBI chr16:17,396,064...17,423,166
Ensembl chr16:17,396,247...17,423,015 		JBrowse link
G Camk2b calcium/calmodulin-dependent protein kinase II beta increases expression ISO Isoproterenol results in increased expression of CAMK2B mRNA CTD PMID:20003209 NCBI chr14:80,845,206...80,934,172
Ensembl chr14:80,845,238...80,933,994 		JBrowse link
G Camk2d calcium/calmodulin-dependent protein kinase II delta multiple interactions
increases expression		 EXP [Carvedilol co-treated with aliskiren] inhibits the reaction [Isoproterenol results in increased expression of CAMK2D protein]; aliskiren inhibits the reaction [Isoproterenol results in increased expression of CAMK2D protein]; Carvedilol inhibits the reaction [Isoproterenol results in increased expression of CAMK2D protein] CTD PMID:26982530 NCBI chr 2:215,023,785...215,287,351
Ensembl chr 2:215,024,004...215,286,178 		JBrowse link
G Camkk2 calcium/calmodulin-dependent protein kinase kinase 2 decreases phosphorylation EXP Isoproterenol results in decreased phosphorylation of CAMKK2 protein CTD PMID:27491814 NCBI chr12:33,791,023...33,845,000
Ensembl chr12:33,791,052...33,843,279 		JBrowse link
G Capn1 calpain 1 increases expression
multiple interactions		 EXP Isoproterenol results in increased expression of CAPN1 mRNA
Quercetin inhibits the reaction [Isoproterenol results in increased expression of CAPN1 mRNA]		 CTD PMID:27527349 NCBI chr 1:203,275,912...203,300,848
Ensembl chr 1:203,277,344...203,300,177 		JBrowse link
G Capn10 calpain 10 increases expression ISO Isoproterenol results in increased expression of CAPN10 mRNA CTD PMID:20003209 NCBI chr 9:93,498,132...93,510,494
Ensembl chr 9:93,498,478...93,510,494 		JBrowse link
G Capn2 calpain 2 multiple interactions
increases expression		 EXP Quercetin inhibits the reaction [Isoproterenol results in increased expression of CAPN2 mRNA] CTD PMID:27527349 NCBI chr13:94,150,244...94,200,969
Ensembl chr13:94,150,240...94,200,969 		JBrowse link
G Car4 carbonic anhydrase 4 increases expression ISO Isoproterenol results in increased expression of CAR4 mRNA CTD PMID:20003209 NCBI chr10:69,827,945...69,836,501
Ensembl chr10:69,827,945...69,836,501 		JBrowse link
G Carmil1 capping protein regulator and myosin 1 linker 1 increases expression ISO Isoproterenol results in increased expression of CARMIL1 mRNA CTD PMID:20003209 NCBI chr17:40,807,921...41,088,326
Ensembl chr17:40,808,389...41,088,326 		JBrowse link
G Casp1 caspase 1 decreases expression
increases expression		 ISO Isoproterenol results in decreased expression of CASP1 mRNA
Isoproterenol results in increased expression of CASP1 mRNA		 CTD PMID:24286936 NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383 		JBrowse link
G Casp2 caspase 2 decreases expression
increases expression		 EXP Isoproterenol results in decreased expression of CASP2 mRNA
Isoproterenol results in increased expression of CASP2 mRNA		 CTD PMID:24286936 NCBI chr 4:71,149,632...71,167,388
Ensembl chr 4:71,149,669...71,167,379 		JBrowse link
G Casp3 caspase 3 multiple interactions
increases expression
increases cleavage
increases activity		 ISO
EXP		 Acetylcysteine inhibits the reaction [Isoproterenol results in increased activity of and results in increased cleavage of CASP3 protein]; BMP10 protein inhibits the reaction [Isoproterenol results in increased expression of CASP3 protein]; Isoproterenol results in increased activity of and results in increased cleavage of CASP3 protein
Isoproterenol results in increased cleavage of CASP3 protein
Isoproterenol results in increased activity of CASP3 protein
[Carvedilol co-treated with aliskiren] inhibits the reaction [Isoproterenol results in increased expression of CASP3 protein]; [erdosteine co-treated with Isoproterenol] affects the expression of CASP3 protein; Acetylcysteine inhibits the reaction [Isoproterenol results in increased expression of CASP3 protein]; aliskiren inhibits the reaction [Isoproterenol results in increased expression of CASP3 protein]; anethole inhibits the reaction [Isoproterenol results in increased cleavage of CASP3 protein]; Apigenin inhibits the reaction [Isoproterenol results in increased expression of CASP3 protein]; benidipine inhibits the reaction [Isoproterenol results in increased activity of CASP3 protein]; Carvedilol inhibits the reaction [Isoproterenol results in increased expression of CASP3 protein]; caryophyllene inhibits the reaction [Isoproterenol results in increased expression of CASP3 mRNA]; Enalapril inhibits the reaction [Isoproterenol results in increased expression of CASP3 protein]; Glyburide promotes the reaction [Isoproterenol results in increased activity of CASP3 protein]; Hesperidin inhibits the reaction [Isoproterenol results in increased expression of CASP3 protein]; pifithrin inhibits the reaction [Isoproterenol results in increased expression of CASP3 protein]; Progesterone inhibits the reaction [Isoproterenol results in increased activity of CASP3 protein]; protocatechuic acid inhibits the reaction [Isoproterenol results in increased activity of CASP3 protein]; punicalagin inhibits the reaction [Isoproterenol results in increased expression of CASP3 protein]; pyrvinium inhibits the reaction [Glyburide promotes the reaction [Isoproterenol results in increased activity of CASP3 protein]]; pyrvinium inhibits the reaction [Isoproterenol results in increased activity of CASP3 protein]; S100A9 protein affects the reaction [Isoproterenol results in increased expression of CASP3 protein]; sodium thiosulfate inhibits the reaction [Isoproterenol results in increased activity of CASP3 protein]; Vanillic Acid inhibits the reaction [Isoproterenol results in increased expression of CASP3 mRNA]; zingiberene inhibits the reaction [Isoproterenol results in increased expression of CASP3 protein]
Isoproterenol results in increased expression of CASP3 mRNA; Isoproterenol results in increased expression of CASP3 protein
BMP10 protein inhibits the reaction [Isoproterenol results in increased expression of CASP3 protein]; Isoproterenol inhibits the reaction [Cisplatin results in increased cleavage of and results in increased activity of CASP3 protein]; RAPGEF3 mutant form inhibits the reaction [Isoproterenol inhibits the reaction [Cisplatin results in increased cleavage of and results in increased activity of CASP3 protein]]; STAT3 protein affects the reaction [BMP10 protein inhibits the reaction [Isoproterenol results in increased expression of CASP3 protein]]		 CTD PMID:11218852 PMID:17136323 PMID:17961425 PMID:20726854 PMID:21745194 More... NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casp6 caspase 6 decreases expression ISO Isoproterenol results in decreased expression of CASP6 mRNA CTD PMID:21335049 NCBI chr 2:218,466,063...218,478,503
Ensembl chr 2:218,466,076...218,478,502 		JBrowse link
G Casp7 caspase 7 multiple interactions
decreases expression		 ISO
EXP		 Acetylcysteine inhibits the reaction [Isoproterenol results in increased activity of and results in increased cleavage of CASP7 protein]; Isoproterenol results in increased activity of and results in increased cleavage of CASP7 protein
[Isoproterenol co-treated with POSTN protein] results in decreased expression of CASP7 mRNA
Isoproterenol results in decreased expression of CASP7 mRNA		 CTD PMID:17136323 PMID:24286936 PMID:30303030 NCBI chr 1:255,437,438...255,476,737
Ensembl chr 1:255,437,172...255,476,729 		JBrowse link
G Casp8 caspase 8 increases expression
multiple interactions		 EXP Isoproterenol results in increased expression of CASP8 mRNA; Isoproterenol results in increased expression of CASP8 protein
Apigenin inhibits the reaction [Isoproterenol results in increased expression of CASP8 protein]; caryophyllene inhibits the reaction [Isoproterenol results in increased expression of CASP8 mRNA]; Thymol inhibits the reaction [Isoproterenol results in increased expression of CASP8 mRNA]; Vanillic Acid inhibits the reaction [Isoproterenol results in increased expression of CASP8 mRNA]		 CTD PMID:25794854 PMID:26996544 PMID:30152906 PMID:34816538 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542 		JBrowse link
G Casp9 caspase 9 increases expression
increases cleavage
increases activity
multiple interactions		 EXP Isoproterenol results in increased expression of CASP9 mRNA; Isoproterenol results in increased expression of CASP9 protein
Isoproterenol results in increased cleavage of CASP9 protein
Isoproterenol results in increased activity of CASP9 protein
anethole inhibits the reaction [Isoproterenol results in increased cleavage of CASP9 protein]; Apigenin inhibits the reaction [Isoproterenol results in increased expression of CASP9 protein]; caryophyllene inhibits the reaction [Isoproterenol results in increased expression of CASP9 mRNA]; sodium thiosulfate inhibits the reaction [Isoproterenol results in increased activity of CASP9 protein]; Thymol inhibits the reaction [Isoproterenol results in increased expression of CASP9 mRNA]; Vanillic Acid inhibits the reaction [Isoproterenol results in increased expression of CASP9 mRNA]		 CTD PMID:24286936 PMID:25794854 PMID:26996544 PMID:30152906 PMID:32865837 More... NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626 		JBrowse link
G Cat catalase decreases expression
decreases activity
multiple interactions
increases activity
increases expression		 ISO
EXP		 Isoproterenol results in decreased expression of CAT protein
Isoproterenol results in decreased activity of CAT protein
5-Methoxypsoralen inhibits the reaction [Isoproterenol results in decreased activity of CAT protein]; [Quercetin co-treated with alpha-Tocopherol] inhibits the reaction [Isoproterenol results in decreased activity of CAT protein]; [Rosuvastatin Calcium co-treated with Isoproterenol] inhibits the reaction [Interleukin-6 results in increased expression of CAT protein]; [Streptozocin co-treated with Isoproterenol] affects the activity of CAT protein; alpha-pinene inhibits the reaction [Isoproterenol results in decreased activity of CAT protein]; anethole inhibits the reaction [Isoproterenol results in decreased activity of CAT protein]; Apigenin inhibits the reaction [Isoproterenol results in decreased activity of CAT protein]; Atenolol inhibits the reaction [Isoproterenol results in decreased activity of CAT protein]; Atenolol promotes the reaction [Quercetin inhibits the reaction [Isoproterenol results in decreased activity of CAT protein]]; benidipine inhibits the reaction [Isoproterenol results in decreased activity of CAT protein]; Carvedilol inhibits the reaction [Isoproterenol results in decreased expression of and results in decreased activity of CAT protein]; caryophyllene inhibits the reaction [Isoproterenol results in decreased activity of CAT protein]; Desmodium gangeticum extract inhibits the reaction [Isoproterenol results in decreased activity of CAT protein]; dicarbine inhibits the reaction [Isoproterenol results in increased activity of CAT protein]; Enalapril inhibits the reaction [Isoproterenol results in decreased expression of CAT protein]; erdosteine inhibits the reaction [Isoproterenol results in decreased activity of CAT protein]; ferruginol inhibits the reaction [Isoproterenol results in decreased activity of CAT protein]; Gallic Acid inhibits the reaction [Isoproterenol results in decreased expression of CAT protein]; geraniol inhibits the reaction [Isoproterenol results in decreased activity of CAT protein]; geraniol inhibits the reaction [Isoproterenol results in decreased expression of CAT mRNA]; Glyburide promotes the reaction [Isoproterenol results in decreased activity of CAT protein]; Hesperidin inhibits the reaction [Isoproterenol results in decreased expression of CAT protein]; imetit inhibits the reaction [Isoproterenol results in decreased expression of and results in decreased activity of CAT protein]; Isoproterenol results in decreased expression of and results in decreased activity of CAT protein; mangiferin inhibits the reaction [Isoproterenol results in decreased activity of CAT protein]; protocatechuic acid inhibits the reaction [Isoproterenol results in decreased activity of CAT protein]; punicalagin inhibits the reaction [Isoproterenol results in decreased activity of CAT protein]; pyrvinium inhibits the reaction [Glyburide promotes the reaction [Isoproterenol results in decreased activity of CAT protein]]; pyrvinium inhibits the reaction [Isoproterenol results in decreased activity of CAT protein]; Quercetin inhibits the reaction [Isoproterenol results in decreased activity of CAT protein]; Quercetin promotes the reaction [Atenolol inhibits the reaction [Isoproterenol results in decreased activity of CAT protein]]; Rosuvastatin Calcium inhibits the reaction [Isoproterenol results in decreased activity of CAT protein]; Thymol inhibits the reaction [Isoproterenol results in decreased activity of CAT protein]; Tretinoin inhibits the reaction [Isoproterenol results in decreased activity of CAT protein]; Vincristine inhibits the reaction [Isoproterenol results in decreased activity of CAT protein]; Vincristine inhibits the reaction [Isoproterenol results in decreased expression of CAT protein]; zingiberene inhibits the reaction [Isoproterenol results in decreased activity of CAT protein]
Isoproterenol results in decreased expression of CAT mRNA; Isoproterenol results in decreased expression of CAT protein
Isoproterenol results in increased expression of CAT mRNA		 CTD PMID:1840475 PMID:12708743 PMID:15740881 PMID:16584858 PMID:16697266 More... NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Cav1 caveolin 1 multiple interactions ISO CAV1 protein promotes the reaction [Isoproterenol results in increased activity of ADRB2 protein] CTD PMID:18820136 NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705 		JBrowse link
G Cav3 caveolin 3 affects localization EXP Isoproterenol affects the localization of CAV3 protein CTD PMID:19299911 NCBI chr 4:145,582,168...145,598,142
Ensembl chr 4:145,582,060...145,598,137 		JBrowse link
G Cblb Cbl proto-oncogene B increases expression ISO Isoproterenol results in increased expression of CBLB mRNA CTD PMID:20003209 NCBI chr11:48,589,878...48,756,940
Ensembl chr11:48,592,703...48,756,839 		JBrowse link
G Ccdc80 coiled-coil domain containing 80 increases expression ISO Isoproterenol results in increased expression of CCDC80 mRNA CTD PMID:20003209 NCBI chr11:55,685,165...55,718,827
Ensembl chr11:55,685,872...55,719,137 		JBrowse link
G Ccdc85a coiled-coil domain containing 85A increases expression ISO Isoproterenol results in increased expression of CCDC85A mRNA CTD PMID:20003209 NCBI chr14:102,126,574...102,359,207
Ensembl chr14:102,129,029...102,359,058 		JBrowse link
G Ccl17 C-C motif chemokine ligand 17 decreases secretion ISO Isoproterenol results in decreased secretion of CCL17 protein CTD PMID:12871855 NCBI chr19:10,202,128...10,203,903
Ensembl chr19:10,202,128...10,203,819 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 increases expression ISO Isoproterenol results in increased expression of CCL2 mRNA CTD PMID:21823215 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226 		JBrowse link
G Ccl3 C-C motif chemokine ligand 3 multiple interactions
increases expression
decreases expression		 ISO Isoproterenol inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of CCL3 protein]
Isoproterenol results in increased expression of CCL3 protein
Isoproterenol results in decreased expression of CCL3 mRNA
Isoproterenol inhibits the reaction [Lipopolysaccharides results in increased secretion of CCL3 protein]		 CTD PMID:9863660 PMID:12538206 PMID:21335049 PMID:24286936 NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938 		JBrowse link
G Ccl7 C-C motif chemokine ligand 7 increases expression
decreases expression		 EXP
ISO		 Isoproterenol results in increased expression of CCL7 mRNA
Isoproterenol results in decreased expression of CCL7 mRNA		 CTD PMID:20211217 PMID:24286936 NCBI chr10:67,016,446...67,018,296
Ensembl chr10:67,016,446...67,018,303 		JBrowse link
G Ccl9 C-C motif chemokine ligand 9 increases expression ISO Isoproterenol results in increased expression of CCL6 mRNA CTD PMID:20003209 NCBI chr10:68,366,486...68,371,408
Ensembl chr10:68,366,487...68,371,369 		JBrowse link
G Ccn2 cellular communication network factor 2 increases expression
multiple interactions
decreases expression		 ISO
EXP		 Isoproterenol results in increased expression of CCN2 mRNA
Isoproterenol results in increased expression of CCN2 mRNA; Isoproterenol results in increased expression of CCN2 protein
Quercetin inhibits the reaction [Isoproterenol results in increased expression of CCN2 mRNA]; Quercetin inhibits the reaction [Isoproterenol results in increased expression of CCN2 protein]; Rutin inhibits the reaction [Isoproterenol results in increased expression of CCN2 mRNA]; Rutin inhibits the reaction [Isoproterenol results in increased expression of CCN2 protein]
Isoproterenol results in decreased expression of CCN2 mRNA		 CTD PMID:20003209 PMID:24117263 PMID:24286936 NCBI chr 1:20,802,199...20,805,315
Ensembl chr 1:20,802,199...20,805,734 		JBrowse link
G Ccnd1 cyclin D1 decreases expression
increases expression		 ISO Isoproterenol results in decreased expression of CCND1 mRNA
Isoproterenol results in increased expression of CCND1 mRNA		 CTD PMID:20003209 PMID:21335049 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602 		JBrowse link
G Ccnd3 cyclin D3 increases expression ISO Isoproterenol results in increased expression of CCND3 mRNA CTD PMID:20003209 NCBI chr 9:13,394,161...13,400,341
Ensembl chr 9:13,394,169...13,489,371 		JBrowse link
G Ccng2 cyclin G2 multiple interactions
increases expression		 ISO Doxycycline inhibits the reaction [Isoproterenol results in increased expression of CCNG2 mRNA] CTD PMID:18089841 PMID:20003209 NCBI chr14:14,804,321...14,812,819
Ensembl chr14:14,804,322...14,812,830 		JBrowse link
G Ccr1 C-C motif chemokine receptor 1 increases expression EXP Isoproterenol results in increased expression of CCR1 mRNA CTD PMID:20211217 NCBI chr 8:123,556,286...123,561,841 JBrowse link
G Cd14 CD14 molecule increases expression EXP
ISO		 Isoproterenol results in increased expression of CD14 mRNA CTD PMID:20003209 PMID:20211217 NCBI chr18:28,335,522...28,337,383
Ensembl chr18:28,335,340...28,337,261 		JBrowse link
G Cd163 CD163 molecule increases expression ISO Isoproterenol results in increased expression of CD163 mRNA CTD PMID:20003209 NCBI chr 4:157,085,080...157,118,470
Ensembl chr 4:157,085,093...157,117,878 		JBrowse link
G Cd302 CD302 molecule increases expression ISO Isoproterenol results in increased expression of CD302 mRNA CTD PMID:20003209 NCBI chr 3:44,722,324...44,756,045
Ensembl chr 3:44,722,325...44,756,045 		JBrowse link
G Cd36 CD36 molecule decreases expression EXP Isoproterenol results in decreased expression of CD36 protein CTD PMID:19826179 NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903 		JBrowse link
G Cd38 CD38 molecule multiple interactions ISO Isoproterenol promotes the reaction [CD38 gene mutant form results in increased activity of REN protein] CTD PMID:23343681 NCBI chr14:67,172,062...67,212,328
Ensembl chr14:67,172,063...67,211,986 		JBrowse link
G Cd74 CD74 molecule decreases expression ISO Isoproterenol results in decreased expression of CD74 mRNA CTD PMID:20003209 NCBI chr18:54,256,757...54,266,003
Ensembl chr18:54,256,778...54,266,003 		JBrowse link
G Cdc37 cell division cycle 37, HSP90 cochaperone multiple interactions EXP [Isoproterenol co-treated with POSTN protein] results in decreased expression of CDC37 mRNA CTD PMID:30303030 NCBI chr 8:19,677,400...19,690,761
Ensembl chr 8:19,671,938...19,690,809 		JBrowse link
G Cdc37l1 cell division cycle 37-like 1 increases expression ISO Isoproterenol results in increased expression of CDC37L1 mRNA CTD PMID:20003209 NCBI chr 1:226,705,019...226,733,994
Ensembl chr 1:226,705,003...226,761,175 		JBrowse link
G Cdc42ep3 CDC42 effector protein 3 decreases expression ISO Isoproterenol results in decreased expression of CDC42EP3 mRNA CTD PMID:20003209 NCBI chr 6:15,710,894...15,731,366
Ensembl chr 6:15,708,730...15,732,721 		JBrowse link
G Cdc42ep4 CDC42 effector protein 4 increases expression ISO Isoproterenol results in increased expression of CDC42EP4 mRNA CTD PMID:20003209 NCBI chr10:98,772,613...98,797,924
Ensembl chr10:98,772,495...98,797,695 		JBrowse link
G Cdh11 cadherin 11 increases expression ISO Isoproterenol results in increased expression of CDH11 mRNA CTD PMID:20003209 NCBI chr19:2,148,447...2,305,754
Ensembl chr19:2,148,458...2,304,272 		JBrowse link
G Cdh13 cadherin 13 decreases expression ISO Isoproterenol results in decreased expression of CDH13 mRNA CTD PMID:20003209 NCBI chr19:46,349,562...47,387,462
Ensembl chr19:46,349,430...47,387,459 		JBrowse link
G Cdh2 cadherin 2 decreases expression ISO Isoproterenol results in decreased expression of CDH2 mRNA CTD PMID:21335049 NCBI chr18:7,776,704...7,990,934
Ensembl chr18:7,776,704...7,990,167 		JBrowse link
G Cdk1 cyclin-dependent kinase 1 increases expression
multiple interactions		 ISO Isoproterenol results in increased expression of CDK1 mRNA; Isoproterenol results in increased expression of CDK1 protein
Atenolol inhibits the reaction [Isoproterenol results in increased expression of CDK1 mRNA]		 CTD PMID:9593584 NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions
increases expression		 ISO Doxycycline inhibits the reaction [Isoproterenol results in increased expression of CDKN1A mRNA] CTD PMID:18089841 PMID:20003209 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585 		JBrowse link
G Cdo1 cysteine dioxygenase type 1 increases expression ISO Isoproterenol results in increased expression of CDO1 mRNA CTD PMID:20003209 NCBI chr18:39,432,473...39,447,253
Ensembl chr18:39,432,474...39,447,296 		JBrowse link
G Cds2 CDP-diacylglycerol synthase 2 increases expression ISO Isoproterenol results in increased expression of CDS2 mRNA CTD PMID:20003209 NCBI chr 3:119,514,963...119,553,555
Ensembl chr 3:119,515,000...119,553,541 		JBrowse link
G Cdv3 carnitine deficiency-associated gene expressed in ventricle 3 increases expression ISO Isoproterenol results in increased expression of CDV3 mRNA CTD PMID:20003209 NCBI chr 8:103,934,006...103,947,173
Ensembl chr 8:103,933,996...103,947,192 		JBrowse link
G Cdyl chromodomain Y-like increases expression ISO Isoproterenol results in increased expression of CDYL mRNA CTD PMID:20003209 NCBI chr17:28,982,009...29,204,345
Ensembl chr17:28,982,037...29,204,313 		JBrowse link
G Cebpd CCAAT/enhancer binding protein delta increases expression ISO Isoproterenol results in increased expression of CEBPD mRNA CTD PMID:20003209 NCBI chr11:84,764,670...84,765,808
Ensembl chr11:84,764,565...84,765,829 		JBrowse link
G Cebpg CCAAT/enhancer binding protein gamma increases expression ISO Isoproterenol results in increased expression of CEBPG mRNA CTD PMID:20003209 NCBI chr 1:87,683,060...87,692,772
Ensembl chr 1:87,684,019...87,694,569 		JBrowse link
G Cenpa centromere protein A decreases expression ISO Isoproterenol results in decreased expression of CENPA mRNA CTD PMID:20003209 NCBI chr 6:25,700,142...25,711,767
Ensembl chr 6:25,700,142...25,711,675 		JBrowse link
G Cep192 centrosomal protein 192 increases expression ISO Isoproterenol results in increased expression of CEP192 mRNA CTD PMID:20003209 NCBI chr18:61,373,937...61,458,405
Ensembl chr18:61,332,158...61,458,379 		JBrowse link
G Cfh complement factor H increases expression ISO Isoproterenol results in increased expression of CFH mRNA CTD PMID:20003209 NCBI chr13:51,512,376...51,613,829
Ensembl chr13:51,511,828...51,613,838 		JBrowse link
G Cftr CF transmembrane conductance regulator multiple interactions
increases activity		 ISO
EXP		 [Isoproterenol co-treated with Adenosine] results in increased activity of CFTR protein; Baclofen promotes the reaction [Isoproterenol results in increased activity of CFTR protein]; Enkephalin, Leucine-2-Alanine promotes the reaction [Isoproterenol results in increased activity of CFTR protein]; Serotonin promotes the reaction [Isoproterenol results in increased activity of CFTR protein] CTD PMID:15020588 PMID:15039139 PMID:15151902 NCBI chr 4:46,561,269...46,728,759
Ensembl chr 4:46,560,885...46,728,756 		JBrowse link
G Ch25h cholesterol 25-hydroxylase increases expression EXP Isoproterenol results in increased expression of CH25H mRNA CTD PMID:20211217 NCBI chr 1:232,014,877...232,016,195
Ensembl chr 1:232,014,880...232,016,195 		JBrowse link
G Chac1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 increases expression ISO Isoproterenol results in increased expression of CHAC1 mRNA CTD PMID:20003209 NCBI chr 3:106,342,302...106,345,526
Ensembl chr 3:106,342,302...106,345,526 		JBrowse link
G Chka choline kinase alpha increases expression ISO Isoproterenol results in increased expression of CHKA mRNA CTD PMID:20003209 NCBI chr 1:201,076,804...201,125,517
Ensembl chr 1:201,076,860...201,125,516 		JBrowse link
G Chuk component of inhibitor of nuclear factor kappa B kinase complex multiple interactions EXP [Isoproterenol co-treated with POSTN protein] results in decreased expression of CHUK mRNA CTD PMID:30303030 NCBI chr 1:242,959,539...242,995,066
Ensembl chr 1:242,959,760...242,995,065 		JBrowse link
G Cidec cell death-inducing DFFA-like effector c multiple interactions ISO Isoproterenol results in increased expression of and results in decreased degradation of CIDEC protein; KT 5720 inhibits the reaction [Isoproterenol results in increased expression of CIDEC protein] CTD PMID:21097823 NCBI chr 4:146,569,288...146,582,173
Ensembl chr 4:146,569,289...146,582,173 		JBrowse link
G Cilp cartilage intermediate layer protein increases expression ISO Isoproterenol results in increased expression of CILP mRNA CTD PMID:20003209 NCBI chr 8:65,777,281...65,792,251
Ensembl chr 8:65,777,281...65,792,251 		JBrowse link
G Cirbp cold inducible RNA binding protein decreases expression ISO Isoproterenol results in decreased expression of CIRBP mRNA CTD PMID:20003209 NCBI chr 7:9,533,857...9,538,899
Ensembl chr 7:9,424,178...9,538,818 		JBrowse link
G Cited2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 increases expression ISO Isoproterenol results in increased expression of CITED2 mRNA CTD PMID:20003209 NCBI chr 1:12,312,426...12,314,869
Ensembl chr 1:12,312,160...12,314,897 		JBrowse link
G Cited4 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4 decreases expression ISO Isoproterenol results in decreased expression of CITED4 mRNA CTD PMID:20003209 NCBI chr 5:134,246,936...134,247,827
Ensembl chr 5:134,246,682...134,248,135 		JBrowse link
G Ckb creatine kinase B multiple interactions
increases activity		 EXP benidipine inhibits the reaction [Isoproterenol results in increased expression of and results in increased secretion of [CKM protein binds to CKB protein]]; Carvedilol inhibits the reaction [Isoproterenol results in increased expression of and results in increased secretion of [CKM protein binds to CKB protein]]; Gallic Acid inhibits the reaction [Isoproterenol results in increased secretion of [CKM protein binds to CKB protein]]; imetit inhibits the reaction [Isoproterenol results in increased expression of and results in increased secretion of [CKM protein binds to CKB protein]]; Isoproterenol results in increased expression of [CKM protein binds to CKB protein]; Isoproterenol results in increased expression of and results in increased secretion of [CKM protein binds to CKB protein]; Isoproterenol results in increased secretion of [CKM protein binds to CKB protein]; Lutein inhibits the reaction [Isoproterenol results in increased activity of CKB protein] CTD PMID:19146839 PMID:22391854 PMID:25269373 PMID:25496245 PMID:34435724 NCBI chr 6:130,729,420...130,732,301
Ensembl chr 6:130,729,423...130,732,315 		JBrowse link
G Ckm creatine kinase, M-type multiple interactions
increases secretion		 EXP [Carvedilol co-treated with aliskiren] inhibits the reaction [Isoproterenol results in increased expression of and results in increased secretion of CKM protein]; aliskiren inhibits the reaction [Isoproterenol results in increased expression of and results in increased secretion of CKM protein]; benidipine inhibits the reaction [Isoproterenol results in increased expression of and results in increased secretion of [CKM protein binds to CKB protein]]; Carvedilol inhibits the reaction [Isoproterenol results in increased expression of and results in increased secretion of [CKM protein binds to CKB protein]]; Carvedilol inhibits the reaction [Isoproterenol results in increased expression of and results in increased secretion of CKM protein]; Gallic Acid inhibits the reaction [Isoproterenol results in increased secretion of [CKM protein binds to CKB protein]]; imetit inhibits the reaction [Isoproterenol results in increased expression of and results in increased secretion of [CKM protein binds to CKB protein]]; Isoproterenol results in increased expression of [CKM protein binds to CKB protein]; Isoproterenol results in increased expression of and results in increased secretion of [CKM protein binds to CKB protein]; Isoproterenol results in increased expression of and results in increased secretion of CKM protein; Isoproterenol results in increased secretion of [CKM protein binds to CKB protein]; Quercetin inhibits the reaction [Isoproterenol results in increased secretion of CKM protein] CTD PMID:19146839 PMID:22391854 PMID:25269373 PMID:25496245 PMID:26982530 More... NCBI chr 1:79,061,390...79,071,721
Ensembl chr 1:79,061,456...79,071,720 		JBrowse link
G Clca1 chloride channel accessory 1 increases expression ISO Isoproterenol results in increased expression of CLCA1 mRNA CTD PMID:20003209 NCBI chr 2:233,938,677...233,964,369
Ensembl chr 2:233,938,677...233,964,369 		JBrowse link
G Clcn3 chloride voltage-gated channel 3 decreases expression ISO Isoproterenol results in decreased expression of CLCN3 mRNA CTD PMID:20003209 NCBI chr16:29,127,152...29,200,133
Ensembl chr16:29,127,419...29,200,119 		JBrowse link
G Clec1a C-type lectin domain family 1, member A increases expression ISO Isoproterenol results in increased expression of CLEC1A mRNA CTD PMID:20003209 NCBI chr 4:162,875,360...162,902,571
Ensembl chr 4:162,877,346...162,901,247 		JBrowse link
G Clec4a C-type lectin domain family 4, member A increases expression ISO Isoproterenol results in increased expression of CLEC4N mRNA CTD PMID:20003209 NCBI chr 4:156,340,439...156,434,212
Ensembl chr 4:156,414,688...156,432,402 		JBrowse link
G Clec4d C-type lectin domain family 4, member D increases expression ISO Isoproterenol results in increased expression of CLEC4D mRNA CTD PMID:20003209 NCBI chr 4:156,589,591...156,599,279
Ensembl chr 4:156,589,792...156,598,848 		JBrowse link
G Clic5 chloride intracellular channel 5 increases expression ISO Isoproterenol results in increased expression of CLIC5 mRNA CTD PMID:20003209 NCBI chr 9:16,710,980...16,813,502
Ensembl chr 9:16,710,980...16,813,427 		JBrowse link
G Clip1 CAP-GLY domain containing linker protein 1 increases expression ISO Isoproterenol results in increased expression of CLIP1 mRNA CTD PMID:20003209 NCBI chr12:32,910,932...33,017,891
Ensembl chr12:32,910,977...33,017,884 		JBrowse link
G Clip4 CAP-GLY domain containing linker protein family, member 4 decreases expression ISO Isoproterenol results in decreased expression of CLIP4 mRNA CTD PMID:20003209 NCBI chr 6:23,616,280...23,697,625
NCBI chr 6:23,718,580...23,729,231
NCBI chr 6:23,597,729...23,601,000
Ensembl chr 6:23,616,281...23,677,874 		JBrowse link
G Clpb ClpB family mitochondrial disaggregase decreases expression ISO Isoproterenol results in decreased expression of CLPB mRNA CTD PMID:20003209 NCBI chr 1:156,028,740...156,158,183
Ensembl chr 1:156,028,930...156,168,788 		JBrowse link
G Clu clusterin increases expression ISO Isoproterenol results in increased expression of CLU mRNA; Isoproterenol results in increased expression of CLU protein CTD PMID:15052282 PMID:20003209 NCBI chr15:40,161,068...40,200,315
Ensembl chr15:40,174,617...40,200,315 		JBrowse link
G Cnksr1 connector enhancer of kinase suppressor of Ras 1 increases expression ISO Isoproterenol results in increased expression of CNKSR1 mRNA CTD PMID:20003209 NCBI chr 5:146,447,495...146,458,332
Ensembl chr 5:146,447,497...146,458,212 		JBrowse link
G Cnksr3 Cnksr family member 3 increases expression ISO Isoproterenol results in increased expression of CNKSR3 mRNA CTD PMID:20003209 NCBI chr 1:43,499,273...43,591,630
Ensembl chr 1:43,499,487...43,591,635 		JBrowse link
G Cobll1 cordon-bleu WH2 repeat protein-like 1 increases expression ISO Isoproterenol results in increased expression of COBLL1 mRNA CTD PMID:20003209 NCBI chr 3:49,753,260...49,915,168
Ensembl chr 3:49,753,262...49,915,194 		JBrowse link
G Col15a1 collagen type XV alpha 1 chain decreases expression ISO Isoproterenol results in decreased expression of COL15A1 mRNA CTD PMID:20003209 NCBI chr 5:61,501,963...61,607,591
Ensembl chr 5:61,501,963...61,607,591 		JBrowse link
G Col1a1 collagen type I alpha 1 chain multiple interactions
increases expression 		EXP
ISO		 manidipine inhibits the reaction [Isoproterenol results in increased expression of COL1A1 mRNA]; MIR214 mRNA promotes the reaction [Isoproterenol results in increased expression of COL1A1 mRNA]
isoprenaline increases expression of Col1a1 protein in blood serum
BMP10 protein inhibits the reaction [Isoproterenol results in increased expression of COL1A1 protein]; celastrol methyl ester inhibits the reaction [Isoproterenol results in increased expression of COL1A1 mRNA]; plantamajoside inhibits the reaction [Isoproterenol results in increased expression of COL1A1 mRNA]; plantamajoside inhibits the reaction [Isoproterenol results in increased expression of COL1A1 protein]; Valsartan inhibits the reaction [Isoproterenol results in increased expression of COL1A1 mRNA]; Valsartan inhibits the reaction [Isoproterenol results in increased expression of COL1A1 protein]
Isoproterenol results in increased expression of COL1A1 mRNA; Isoproterenol results in increased expression of COL1A1 protein		 CTD
RGD		 PMID:9559417 PMID:24945829 PMID:26692091 PMID:28526319 PMID:31009642 More... RGD:156430318 NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624 		JBrowse link
G Col2a1 collagen type II alpha 1 chain multiple interactions
decreases expression		 ISO [N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide co-treated with U 0126] inhibits the reaction [Isoproterenol results in decreased expression of COL2A1 mRNA]; [N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide co-treated with U 0126] inhibits the reaction [Isoproterenol results in decreased expression of COL2A1 protein]; DUSP1 protein inhibits the reaction [Isoproterenol results in decreased expression of COL2A1 mRNA]; DUSP1 protein inhibits the reaction [Isoproterenol results in decreased expression of COL2A1 protein]; JUNB protein promotes the reaction [Isoproterenol results in decreased expression of COL2A1 mRNA]; MAP2K1 protein promotes the reaction [Isoproterenol results in decreased expression of COL2A1 mRNA]; MAP2K1 protein promotes the reaction [Isoproterenol results in decreased expression of COL2A1 protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Isoproterenol results in decreased expression of COL2A1 mRNA]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Isoproterenol results in decreased expression of COL2A1 protein]; Propranolol inhibits the reaction [Isoproterenol results in decreased expression of COL2A1 mRNA]; Propranolol inhibits the reaction [Isoproterenol results in decreased expression of COL2A1 protein]; U 0126 inhibits the reaction [Isoproterenol results in decreased expression of COL2A1 mRNA]; U 0126 inhibits the reaction [Isoproterenol results in decreased expression of COL2A1 protein]
Isoproterenol results in decreased expression of COL2A1 mRNA; Isoproterenol results in decreased expression of COL2A1 protein		 CTD PMID:21177286 NCBI chr 7:129,098,489...129,127,560
Ensembl chr 7:129,098,786...129,127,546 		JBrowse link
G Col3a1 collagen type III alpha 1 chain multiple interactions
increases expression 		EXP
ISO		 AGT inhibits the reaction [Isoproterenol results in increased expression of COL3A1 protein]; manidipine inhibits the reaction [Isoproterenol results in increased expression of COL3A1 mRNA]; MIR214 mRNA promotes the reaction [Isoproterenol results in increased expression of COL3A1 mRNA]
isoprenaline increases expression of Col3a1 protein in blood serum
Isoproterenol results in increased expression of COL3A1 mRNA; Isoproterenol results in increased expression of COL3A1 protein
BMP10 protein inhibits the reaction [Isoproterenol results in increased expression of COL3A1 protein]; plantamajoside inhibits the reaction [Isoproterenol results in increased expression of COL3A1 mRNA]; plantamajoside inhibits the reaction [Isoproterenol results in increased expression of COL3A1 protein]; Valsartan inhibits the reaction [Isoproterenol results in increased expression of COL3A1 mRNA]; Valsartan inhibits the reaction [Isoproterenol results in increased expression of COL3A1 protein]		 CTD
RGD		 PMID:9559417 PMID:20409916 PMID:26692091 PMID:31009642 PMID:31712309 More... RGD:156430318 NCBI chr 9:47,374,611...47,410,547
Ensembl chr 9:47,374,593...47,410,547 		JBrowse link
G Col5a1 collagen type V alpha 1 chain decreases expression ISO Isoproterenol results in decreased expression of COL5A1 mRNA CTD PMID:21335049 NCBI chr 3:11,208,429...11,356,715
Ensembl chr 3:11,208,512...11,354,588 		JBrowse link
G Col5a2 collagen type V alpha 2 chain increases expression ISO Isoproterenol results in increased expression of COL5A2 mRNA CTD PMID:20003209 NCBI chr 9:47,448,741...47,598,134
Ensembl chr 9:47,448,736...47,598,154 		JBrowse link
G Comt catechol-O-methyltransferase increases methylation ISO COMT protein results in increased methylation of Isoproterenol CTD PMID:11160877 NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642 		JBrowse link
G Cops3 COP9 signalosome subunit 3 multiple interactions EXP [Isoproterenol co-treated with POSTN protein] results in decreased expression of COPS3 mRNA CTD PMID:30303030 NCBI chr10:44,618,115...44,652,807
Ensembl chr10:44,618,115...44,641,597 		JBrowse link
G Corin corin, serine peptidase increases expression ISO Isoproterenol results in increased expression of CORIN mRNA CTD PMID:20003209 NCBI chr14:35,680,601...35,910,703
Ensembl chr14:35,681,304...35,909,503 		JBrowse link
G Cp ceruloplasmin multiple interactions
increases expression
decreases activity		 EXP
ISO		 allyl sulfide inhibits the reaction [Isoproterenol results in decreased activity of CP protein]
Isoproterenol results in increased expression of CP protein
Isoproterenol results in increased expression of CP mRNA		 CTD PMID:1521861 PMID:15261977 PMID:20003209 NCBI chr 2:102,439,433...102,498,075
Ensembl chr 2:102,439,624...102,498,075 		JBrowse link
G Cpne8 copine 8 increases expression ISO Isoproterenol results in increased expression of CPNE8 mRNA CTD PMID:20003209 NCBI chr 7:121,615,293...121,789,507
Ensembl chr 7:121,615,294...121,790,377 		JBrowse link
G Cps1 carbamoyl-phosphate synthase 1 increases expression ISO Isoproterenol results in increased expression of CPS1 mRNA CTD PMID:21335049 NCBI chr 9:68,614,153...68,737,037
Ensembl chr 9:68,614,153...68,737,033 		JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A multiple interactions EXP [Isoproterenol co-treated with POSTN protein] results in decreased expression of CPT1A mRNA CTD PMID:30303030 NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:200,565,613...200,627,055 		JBrowse link
G Cpt1b carnitine palmitoyltransferase 1B multiple interactions
decreases expression		 EXP Sirolimus inhibits the reaction [Isoproterenol results in decreased expression of CPT1B mRNA]; TNF protein inhibits the reaction [Sirolimus inhibits the reaction [Isoproterenol results in decreased expression of CPT1B mRNA]] CTD PMID:25045214 NCBI chr 7:120,491,354...120,500,833
Ensembl chr 7:120,491,354...120,500,404 		JBrowse link
G Cpt2 carnitine palmitoyltransferase 2 decreases expression
multiple interactions		 EXP Isoproterenol results in decreased expression of CPT2 mRNA
[Isoproterenol co-treated with POSTN protein] results in decreased expression of CPT2 mRNA; Sirolimus inhibits the reaction [Isoproterenol results in decreased expression of CPT2 mRNA]; TNF protein inhibits the reaction [Sirolimus inhibits the reaction [Isoproterenol results in decreased expression of CPT2 mRNA]]		 CTD PMID:25045214 PMID:30303030 NCBI chr 5:122,664,677...122,682,126
Ensembl chr 5:122,664,677...122,682,095 		JBrowse link
G Crb1 crumbs cell polarity complex component 1 increases expression ISO Isoproterenol results in increased expression of CRB1 mRNA CTD PMID:20003209 NCBI chr13:50,801,484...50,989,261
Ensembl chr13:50,800,959...50,989,261 		JBrowse link
G Crbn cereblon increases expression ISO Isoproterenol results in increased expression of CRBN mRNA CTD PMID:20003209 NCBI chr 4:139,701,154...139,719,949
Ensembl chr 4:139,701,094...139,719,938 		JBrowse link
G Creb1 cAMP responsive element binding protein 1 multiple interactions
increases phosphorylation		 ISO
EXP		 oxophenylarsine inhibits the reaction [Isoproterenol results in increased phosphorylation of CREB1 protein]
CREM protein inhibits the reaction [Isoproterenol results in increased activity of CREB1 protein]; swietenine inhibits the reaction [Isoproterenol results in increased phosphorylation of CREB1 protein]		 CTD PMID:12791704 PMID:17141199 PMID:21745194 PMID:32686902 NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816 		JBrowse link
G Crem cAMP responsive element modulator multiple interactions
increases expression
affects localization		 EXP CREM protein inhibits the reaction [Isoproterenol results in increased activity of CREB1 protein]; CREM protein inhibits the reaction [Isoproterenol results in increased expression of FOS mRNA]; CREM protein inhibits the reaction [Isoproterenol results in increased expression of NPPA protein]
Isoproterenol results in increased expression of CREM mRNA; Isoproterenol results in increased expression of CREM protein
Isoproterenol affects the localization of CREM protein		 CTD PMID:12791704 PMID:20211217 NCBI chr17:54,238,889...54,305,989
Ensembl chr17:54,239,030...54,305,989 		JBrowse link
G Crlf1 cytokine receptor-like factor 1 increases expression ISO Isoproterenol results in increased expression of CRLF1 mRNA CTD PMID:20003209 NCBI chr16:18,924,722...18,936,049
Ensembl chr16:18,924,722...18,935,997 		JBrowse link
G Crp C-reactive protein increases expression
multiple interactions		 EXP Isoproterenol results in increased expression of CRP protein
benidipine inhibits the reaction [Isoproterenol results in increased expression of and results in increased secretion of CRP protein]; geraniol inhibits the reaction [Isoproterenol results in increased expression of CRP protein]; Isoproterenol results in increased expression of and results in increased secretion of CRP protein; p-coumaric acid inhibits the reaction [Isoproterenol results in increased expression of CRP protein]		 CTD PMID:25269373 PMID:35608392 PMID:38439645 NCBI chr13:85,135,384...85,175,178
Ensembl chr13:85,124,977...85,175,178 		JBrowse link
G Cryab crystallin, alpha B multiple interactions EXP Isoproterenol inhibits the reaction [arsenite results in increased expression of CRYAB protein] CTD PMID:8769853 NCBI chr 8:51,093,441...51,099,161
Ensembl chr 8:51,093,441...51,099,157 		JBrowse link
G Cryba4 crystallin, beta A4 decreases expression ISO Isoproterenol results in decreased expression of CRYBA4 mRNA CTD PMID:20003209 NCBI chr12:44,378,734...44,393,226
Ensembl chr12:44,378,737...44,393,221 		JBrowse link
G Cs citrate synthase decreases activity EXP Isoproterenol results in decreased activity of CS protein CTD PMID:27491814 NCBI chr 7:758,074...791,421
Ensembl chr 7:758,345...791,421 		JBrowse link
G Csdc2 cold shock domain containing C2 increases expression ISO Isoproterenol results in increased expression of CSDC2 mRNA CTD PMID:20003209 NCBI chr 7:113,451,998...113,466,464
Ensembl chr 7:113,451,998...113,466,463 		JBrowse link
G Csf2rb colony stimulating factor 2 receptor subunit beta increases expression ISO Isoproterenol results in increased expression of CSF2RB mRNA; Isoproterenol results in increased expression of CSF2RB2 mRNA CTD PMID:20003209 NCBI chr 7:109,876,919...109,901,589
Ensembl chr 7:109,886,425...109,904,157 		JBrowse link
G Csk C-terminal Src kinase multiple interactions ISO CSK protein promotes the reaction [Isoproterenol results in increased abundance of Cyclic AMP]; Isoproterenol inhibits the reaction [CSK protein promotes the reaction [Epinephrine results in increased abundance of Cyclic AMP]] CTD PMID:1699227 NCBI chr 8:58,029,748...58,048,742
Ensembl chr 8:58,029,749...58,048,292 		JBrowse link
G Ctf1 cardiotrophin 1 increases expression
multiple interactions		 EXP Isoproterenol results in increased expression of CTF1 mRNA; Isoproterenol results in increased expression of CTF1 protein
Spironolactone inhibits the reaction [Isoproterenol results in increased expression of CTF1 mRNA]; Spironolactone inhibits the reaction [Isoproterenol results in increased expression of CTF1 protein]; Valsartan inhibits the reaction [Isoproterenol results in increased expression of CTF1 mRNA]; Valsartan inhibits the reaction [Isoproterenol results in increased expression of CTF1 protein]		 CTD PMID:23288202 NCBI chr 1:182,328,035...182,336,346
Ensembl chr 1:182,328,090...182,333,335 		JBrowse link
G Cth cystathionine gamma-lyase multiple interactions EXP [Isoproterenol co-treated with Caffeine] results in decreased expression of CTH mRNA CTD PMID:29447158 NCBI chr 2:246,975,888...247,002,234
Ensembl chr 2:246,975,894...247,002,234 		JBrowse link
G Cthrc1 collagen triple helix repeat containing 1 increases expression ISO Isoproterenol results in increased expression of CTHRC1 mRNA CTD PMID:20003209 NCBI chr 7:70,122,474...70,132,756
Ensembl chr 7:70,122,474...70,132,756 		JBrowse link
G Ctnnal1 catenin alpha-like 1 increases expression ISO Isoproterenol results in increased expression of CTNNAL1 mRNA CTD PMID:20003209 NCBI chr 5:71,514,340...71,569,431
Ensembl chr 5:71,514,340...71,569,431 		JBrowse link
G Ctnnb1 catenin beta 1 increases expression
multiple interactions		 EXP Isoproterenol results in increased expression of CTNNB1 mRNA; Isoproterenol results in increased expression of CTNNB1 protein
[Glyburide co-treated with Isoproterenol] results in increased expression of CTNNB1 mRNA; Glyburide promotes the reaction [Isoproterenol results in increased expression of CTNNB1 protein]; pyrvinium inhibits the reaction [[Glyburide co-treated with Isoproterenol] results in increased expression of CTNNB1 mRNA]; pyrvinium inhibits the reaction [Glyburide promotes the reaction [Isoproterenol results in increased expression of CTNNB1 protein]]; pyrvinium inhibits the reaction [Isoproterenol results in increased expression of CTNNB1 mRNA]; pyrvinium inhibits the reaction [Isoproterenol results in increased expression of CTNNB1 protein]		 CTD PMID:35305975 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111 		JBrowse link
G Ctnnbip1 catenin, beta-interacting protein 1 decreases expression ISO Isoproterenol results in decreased expression of CTNNBIP1 mRNA CTD PMID:20003209 NCBI chr 5:159,961,961...160,010,942
Ensembl chr 5:159,961,928...160,010,939 		JBrowse link
G Ctps2 CTP synthase 2 increases expression ISO Isoproterenol results in increased expression of CTPS2 mRNA CTD PMID:20003209 NCBI chr  X:31,645,873...31,786,733
Ensembl chr  X:31,645,873...31,786,733 		JBrowse link
G Ctsb cathepsin B multiple interactions
increases activity
decreases expression
decreases activity		 EXP
ISO		 Arbutin inhibits the reaction [Isoproterenol results in increased activity of CTSB protein]; caffeic acid inhibits the reaction [Isoproterenol results in increased activity of CTSB protein]; Curcumin inhibits the reaction [Isoproterenol results in increased activity of CTSB protein]; epigallocatechin gallate inhibits the reaction [Isoproterenol results in increased activity of CTSB protein]; naringin inhibits the reaction [Isoproterenol results in decreased activity of CTSB protein]; naringin inhibits the reaction [Isoproterenol results in increased activity of CTSB protein]; Phytic Acid inhibits the reaction [Isoproterenol results in increased activity of CTSB protein]
Isoproterenol results in decreased expression of CTSB mRNA		 CTD PMID:2015110 PMID:8534267 PMID:17188415 PMID:18294627 PMID:20391626 More... NCBI chr15:37,389,636...37,410,508
Ensembl chr15:37,389,629...37,410,500 		JBrowse link
G Ctsd cathepsin D multiple interactions
affects activity
increases activity
decreases activity
increases expression		 EXP [ferulic acid co-treated with Ascorbic Acid] inhibits the reaction [Isoproterenol results in increased activity of CTSD protein]; [Nicorandil co-treated with Amlodipine] inhibits the reaction [Isoproterenol results in decreased activity of CTSD protein]; [Nicorandil co-treated with Amlodipine] inhibits the reaction [Isoproterenol results in increased activity of CTSD protein]; alliin affects the reaction [Isoproterenol affects the activity of CTSD protein]; Arbutin inhibits the reaction [Isoproterenol results in increased activity of CTSD protein]; caffeic acid inhibits the reaction [Isoproterenol affects the activity of CTSD protein]; Curcumin inhibits the reaction [Isoproterenol results in decreased activity of CTSD protein]; Curcumin inhibits the reaction [Isoproterenol results in increased activity of CTSD protein]; Ellagic Acid inhibits the reaction [Isoproterenol results in increased activity of CTSD protein]; epigallocatechin gallate inhibits the reaction [Isoproterenol affects the activity of CTSD protein]; mangiferin inhibits the reaction [Isoproterenol results in decreased activity of CTSD protein]; Methylprednisolone inhibits the reaction [Isoproterenol results in increased expression of CTSD mRNA]; naringin inhibits the reaction [Isoproterenol results in increased activity of CTSD protein]; Phytic Acid inhibits the reaction [Isoproterenol results in increased activity of CTSD protein]; Plant Extracts inhibits the reaction [Isoproterenol results in increased activity of CTSD protein]; S-allylcysteine inhibits the reaction [Isoproterenol results in increased expression of CTSD mRNA]
Isoproterenol results in increased expression of CTSD mRNA; Isoproterenol results in increased expression of CTSD protein		 CTD PMID:894732 PMID:2015110 PMID:8534267 PMID:11829124 PMID:14499179 More... NCBI chr 1:197,527,467...197,539,343
Ensembl chr 1:197,527,467...197,539,488 		JBrowse link
G Ctsl cathepsin L increases expression ISO Isoproterenol results in increased expression of CTSL mRNA CTD PMID:20003209 NCBI chr17:764,370...770,533
Ensembl chr17:764,309...770,548 		JBrowse link
G Cul1 cullin 1 multiple interactions EXP [Isoproterenol co-treated with POSTN protein] results in decreased expression of CUL1 mRNA CTD PMID:30303030 NCBI chr 4:76,551,952...76,625,830
Ensembl chr 4:76,551,983...76,627,980 		JBrowse link
G Cul4b cullin 4B increases expression ISO Isoproterenol results in increased expression of CUL4B mRNA CTD PMID:20003209 NCBI chr  X:117,287,481...117,326,688
Ensembl chr  X:117,287,484...117,326,688 		JBrowse link
G Cux2 cut-like homeobox 2 decreases expression ISO Isoproterenol results in decreased expression of CUX2 mRNA CTD PMID:20003209 NCBI chr12:34,507,723...34,707,581
Ensembl chr12:34,520,959...34,705,806 		JBrowse link
G Cuzd1 CUB and zona pellucida-like domains 1 increases expression ISO Isoproterenol results in increased expression of CUZD1 mRNA CTD PMID:20003209 NCBI chr 1:186,089,422...186,130,536
Ensembl chr 1:186,089,423...186,102,546 		JBrowse link
G Cxcl13 C-X-C motif chemokine ligand 13 increases expression ISO Isoproterenol results in increased expression of CXCL13 mRNA CTD PMID:20003209 NCBI chr14:13,608,894...13,613,965
Ensembl chr14:13,608,902...13,613,933 		JBrowse link
G Cxcl9 C-X-C motif chemokine ligand 9 decreases expression ISO Isoproterenol results in decreased expression of CXCL9 mRNA CTD PMID:20003209 NCBI chr14:15,722,868...15,727,779
Ensembl chr14:15,722,908...15,728,435 		JBrowse link
G Cxcr2 C-X-C motif chemokine receptor 2 increases activity ISO Isoproterenol results in increased activity of CXCR2 protein CTD PMID:15477226 NCBI chr 9:75,729,493...75,735,868
Ensembl chr 9:75,729,115...75,739,425 		JBrowse link
G Cxxc5 CXXC finger protein 5 decreases expression ISO Isoproterenol results in decreased expression of CXXC5 mRNA CTD PMID:20003209 NCBI chr18:27,427,591...27,458,579
Ensembl chr18:27,427,230...27,458,673 		JBrowse link
G Cyba cytochrome b-245 alpha chain increases expression
multiple interactions		 EXP Isoproterenol results in increased expression of CYBA mRNA
CPU0213 inhibits the reaction [Isoproterenol results in increased expression of CYBA mRNA]; pimagedine inhibits the reaction [Isoproterenol results in increased expression of CYBA mRNA]		 CTD PMID:18594475 NCBI chr19:50,487,598...50,495,669
Ensembl chr19:50,487,597...50,495,721 		JBrowse link
G Cycs cytochrome c, somatic increases expression
multiple interactions		 EXP Isoproterenol results in increased expression of CYCS protein
Apigenin inhibits the reaction [Isoproterenol results in increased expression of CYCS protein]; zingiberene inhibits the reaction [Isoproterenol results in increased expression of CYCS protein]		 CTD PMID:30152906 PMID:33242989 NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054
Ensembl chr18:79,651,378...79,654,054 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 decreases expression
increases expression
multiple interactions		 ISO
EXP		 Isoproterenol results in decreased expression of CYP1A1 mRNA
Isoproterenol results in increased expression of CYP1A1 mRNA
Isoproterenol inhibits the reaction [Lipopolysaccharides results in decreased activity of CYP1A1 protein]; Propranolol inhibits the reaction [Isoproterenol inhibits the reaction [Lipopolysaccharides results in decreased activity of CYP1A1 protein]]		 CTD PMID:15627480 PMID:15710352 PMID:18725507 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions ISO
EXP		 Isoproterenol inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]
Isoproterenol inhibits the reaction [Lipopolysaccharides results in decreased activity of CYP1A2 protein]; Propranolol inhibits the reaction [Isoproterenol inhibits the reaction [Lipopolysaccharides results in decreased activity of CYP1A2 protein]]		 CTD PMID:15710352 PMID:18493746 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312 		JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 increases expression EXP
ISO		 Isoproterenol results in increased expression of CYP1B1 mRNA CTD PMID:18725507 PMID:20003209 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917 		JBrowse link
G Cyp26b1 cytochrome P450, family 26, subfamily b, polypeptide 1 decreases expression ISO Isoproterenol results in decreased expression of CYP26B1 mRNA CTD PMID:20003209 NCBI chr 4:117,041,808...117,058,628
Ensembl chr 4:117,041,808...117,058,628 		JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 increases expression ISO Isoproterenol results in increased expression of CYP2B10 mRNA CTD PMID:20003209 NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143 		JBrowse link
G Cyp2c11 cytochrome P450, subfamily 2, polypeptide 11 decreases expression EXP Isoproterenol results in decreased expression of CYP2C11 mRNA CTD PMID:18725507 NCBI chr 1:236,762,719...236,799,069
Ensembl chr 1:236,762,842...236,799,066 		JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 affects expression EXP Isoproterenol affects the expression of CYP2E1 mRNA CTD PMID:18725507 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023 		JBrowse link
G Cyp4a3 cytochrome P450, family 4, subfamily a, polypeptide 3 increases expression EXP Isoproterenol results in increased expression of CYP4A3 mRNA CTD PMID:18725507 NCBI chr 5:129,097,571...129,115,488
Ensembl chr 5:129,097,926...129,115,463 		JBrowse link
G Cysltr1 cysteinyl leukotriene receptor 1 increases expression ISO Isoproterenol results in increased expression of CYSLTR1 mRNA CTD PMID:20003209 NCBI chr  X:71,661,421...71,690,012
Ensembl chr  X:71,663,821...71,690,121 		JBrowse link
G Cyss cystatin S multiple interactions
increases expression		 EXP Reserpine inhibits the reaction [Isoproterenol results in increased expression of CYSS mRNA] CTD PMID:9447264 NCBI chr 3:137,432,049...137,436,654
Ensembl chr 3:137,432,049...137,436,610 		JBrowse link
G Dag1 dystroglycan 1 decreases expression EXP Isoproterenol results in decreased expression of DAG1 CTD PMID:18808529 NCBI chr 8:108,890,926...108,955,611
Ensembl chr 8:108,890,929...108,952,325 		JBrowse link
G Dap death-associated protein multiple interactions
increases expression		 EXP [Isoproterenol co-treated with POSTN protein] results in increased expression of DAP mRNA
Isoproterenol results in increased expression of DAP mRNA		 CTD PMID:30303030 NCBI chr 2:82,199,206...82,251,771
Ensembl chr 2:82,199,280...82,251,752 		JBrowse link
G Dbp D-box binding PAR bZIP transcription factor decreases expression ISO Isoproterenol results in decreased expression of DBP mRNA CTD PMID:20003209 NCBI chr 1:96,175,796...96,180,745
Ensembl chr 1:96,175,440...96,180,745 		JBrowse link
G Dcakd dephospho-CoA kinase domain containing decreases expression ISO Isoproterenol results in decreased expression of DCAKD mRNA CTD PMID:20003209 NCBI chr10:87,957,738...87,989,002
Ensembl chr10:87,957,740...87,980,054 		JBrowse link
G Dcn decorin increases expression ISO Isoproterenol results in increased expression of DCN mRNA CTD PMID:20003209 NCBI chr 7:32,281,252...32,321,291
Ensembl chr 7:32,281,252...32,321,270 		JBrowse link
G Dct dopachrome tautomerase increases expression ISO Isoproterenol results in increased expression of DCT mRNA CTD PMID:20003209 NCBI chr15:95,062,006...95,100,863
Ensembl chr15:95,062,003...95,100,836 		JBrowse link
G Dctn5 dynactin subunit 5 increases expression ISO Isoproterenol results in increased expression of DCTN5 mRNA CTD PMID:21335049 NCBI chr 1:176,689,176...176,705,907
Ensembl chr 1:176,689,156...176,705,906 		JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression
multiple interactions		 ISO
EXP		 Isoproterenol results in increased expression of DDIT3 mRNA
[Acrolein results in increased susceptibility to Isoproterenol] which results in increased expression of DDIT3 protein; Acrolein promotes the reaction [Isoproterenol results in increased expression of DDIT3 mRNA]; Plant Extracts inhibits the reaction [[Acrolein results in increased susceptibility to Isoproterenol] which results in increased expression of DDIT3 protein]; Plant Extracts inhibits the reaction [Acrolein promotes the reaction [Isoproterenol results in increased expression of DDIT3 mRNA]]		 CTD PMID:21823215 PMID:29414845 NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201 		JBrowse link
G Ddit4 DNA-damage-inducible transcript 4 multiple interactions
increases expression		 ISO Doxycycline inhibits the reaction [Isoproterenol results in increased expression of DDIT4 mRNA] CTD PMID:18089841 PMID:20003209 NCBI chr20:27,891,989...27,894,088
Ensembl chr20:27,891,998...27,894,105 		JBrowse link
G Ddost dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit increases expression ISO Isoproterenol results in increased expression of DDOST mRNA CTD PMID:21823215 NCBI chr 5:150,522,297...150,529,413
Ensembl chr 5:150,522,242...150,529,413 		JBrowse link
G Defb1 defensin beta 1 decreases expression
increases expression		 EXP Isoproterenol results in decreased expression of DEFB1 mRNA
Isoproterenol results in increased expression of DEFB1 mRNA		 CTD PMID:24286936 NCBI chr16:70,298,862...70,313,604
Ensembl chr16:70,298,863...70,313,604 		JBrowse link
G Dennd4a DENN domain containing 4A increases expression ISO Isoproterenol results in increased expression of DENND4A mRNA CTD PMID:20003209 NCBI chr 8:65,322,920...65,436,331
Ensembl chr 8:65,322,941...65,436,330 		JBrowse link
G Derl2 derlin 2 increases expression ISO Isoproterenol results in increased expression of DERL2 mRNA CTD PMID:21823215 NCBI chr10:55,727,764...55,739,442
Ensembl chr10:55,727,643...55,739,518 		JBrowse link
G Derl3 derlin 3 decreases expression ISO Isoproterenol results in decreased expression of DERL3 mRNA CTD PMID:21823215 NCBI chr20:12,754,490...12,768,454
Ensembl chr20:12,763,543...12,767,027 		JBrowse link
G Des desmin decreases expression
multiple interactions		 EXP Isoproterenol results in decreased expression of DES protein
Lutein inhibits the reaction [Isoproterenol results in decreased expression of DES protein]		 CTD PMID:34435724 NCBI chr 9:76,850,979...76,858,695
Ensembl chr 9:76,850,982...76,858,699 		JBrowse link
G Dffb DNA fragmentation factor subunit beta increases expression ISO Isoproterenol results in increased expression of DFFB mRNA CTD PMID:20003209 NCBI chr 5:164,522,446...164,534,733
Ensembl chr 5:164,522,463...164,534,628 		JBrowse link
G Dhcr24 24-dehydrocholesterol reductase decreases expression ISO Isoproterenol results in decreased expression of DHCR24 mRNA CTD PMID:20003209 NCBI chr 5:121,344,552...121,371,124
Ensembl chr 5:121,344,575...121,371,137 		JBrowse link
G Dhrs3 dehydrogenase/reductase 3 decreases expression ISO Isoproterenol results in decreased expression of DHRS3 mRNA CTD PMID:21335049 NCBI chr 5:156,747,939...156,782,420
Ensembl chr 5:156,747,962...156,782,417 		JBrowse link
G Dhrs7 dehydrogenase/reductase 7 decreases expression ISO Isoproterenol results in decreased expression of DHRS7 mRNA CTD PMID:20003209 PMID:21335049 NCBI chr 6:91,332,259...91,347,856
Ensembl chr 6:91,251,323...91,347,892 		JBrowse link
G Dhrs7c dehydrogenase/reductase 7C decreases expression ISO Isoproterenol results in decreased expression of DHRS7C mRNA CTD PMID:20003209 NCBI chr10:52,495,262...52,513,338
Ensembl chr10:52,495,262...52,513,338 		JBrowse link
G Diaph2 diaphanous-related formin 2 increases expression ISO Isoproterenol results in increased expression of DIAPH2 mRNA CTD PMID:20003209 NCBI chr  X:92,395,189...93,234,521
Ensembl chr  X:92,395,251...93,229,869 		JBrowse link
G Dio2 iodothyronine deiodinase 2 increases expression
increases activity		 ISO
EXP		 Isoproterenol results in increased expression of DIO2 mRNA
Isoproterenol results in increased activity of DIO2 protein		 CTD PMID:15345674 PMID:20003209 NCBI chr 6:109,665,523...109,679,809
Ensembl chr 6:109,665,523...109,679,809 		JBrowse link
G Dixdc1 DIX domain containing 1 increases expression ISO Isoproterenol results in increased expression of DIXDC1 mRNA CTD PMID:20003209 NCBI chr 8:51,007,835...51,081,191
Ensembl chr 8:51,007,838...51,081,090 		JBrowse link
G Dlat dihydrolipoamide S-acetyltransferase decreases expression ISO Isoproterenol results in decreased expression of DLAT mRNA CTD PMID:21335049 NCBI chr 8:50,979,151...51,004,435
Ensembl chr 8:50,978,051...51,004,479
Ensembl chr 1:50,978,051...51,004,479 		JBrowse link
G Dmac2l distal membrane arm assembly component 2 like multiple interactions EXP [Isoproterenol co-treated with POSTN protein] results in decreased expression of DMAC2L mRNA CTD PMID:30303030 NCBI chr 6:88,205,580...88,223,934
Ensembl chr 6:88,205,700...88,223,933 		JBrowse link
G Dmd dystrophin multiple interactions
decreases expression		 ISO
EXP		 DMD gene mutant form promotes the reaction [ITGB1 gene affects the susceptibility to Isoproterenol]
Isoproterenol results in decreased expression of DMD		 CTD PMID:18340010 PMID:18808529 NCBI chr  X:47,272,324...49,504,219
Ensembl chr  X:47,272,331...49,504,207 		JBrowse link
G Dnajb11 DnaJ heat shock protein family (Hsp40) member B11 increases expression ISO Isoproterenol results in increased expression of DNAJB11 mRNA CTD PMID:21823215 NCBI chr11:78,151,750...78,168,259
Ensembl chr11:78,150,429...78,180,407 		JBrowse link
G Dnajb9 DnaJ heat shock protein family (Hsp40) member B9 increases expression ISO Isoproterenol results in increased expression of DNAJB9 mRNA CTD PMID:21335049 NCBI chr 6:61,270,385...61,276,795
Ensembl chr 6:61,269,913...61,275,063 		JBrowse link
G Dnm1l dynamin 1-like increases phosphorylation EXP Isoproterenol results in increased phosphorylation of DNM1L protein CTD PMID:27491814 NCBI chr11:84,581,216...84,632,382
Ensembl chr11:84,581,216...84,631,482 		JBrowse link
G Dnmt3a DNA methyltransferase 3 alpha decreases expression
increases expression		 ISO
EXP		 Isoproterenol results in decreased expression of DNMT3A mRNA
Isoproterenol results in increased expression of DNMT3A protein		 CTD PMID:20003209 PMID:24945829 NCBI chr 6:26,791,517...26,902,161
Ensembl chr 6:26,822,609...26,896,687 		JBrowse link
G Dnmt3b DNA methyltransferase 3 beta increases expression ISO Isoproterenol results in increased expression of DNMT3B mRNA CTD PMID:21335049 NCBI chr 3:142,130,588...142,169,128
Ensembl chr 3:142,130,592...142,169,124 		JBrowse link
G Dnttip2 deoxynucleotidyltransferase, terminal, interacting protein 2 increases expression ISO Isoproterenol results in increased expression of DNTTIP2 mRNA CTD PMID:20003209 NCBI chr 2:210,374,321...210,386,366
Ensembl chr 2:210,374,289...210,385,581 		JBrowse link
G Dock10 dedicator of cytokinesis 10 increases expression ISO Isoproterenol results in increased expression of DOCK10 mRNA CTD PMID:20003209 NCBI chr 9:81,843,599...82,101,540
Ensembl chr 9:81,843,604...82,101,525 		JBrowse link
G Dock9 dedicator of cytokinesis 9 increases expression ISO Isoproterenol results in increased expression of DOCK9 mRNA CTD PMID:20003209 NCBI chr15:98,611,518...98,883,306
Ensembl chr15:98,618,084...98,883,153 		JBrowse link
G Dpep1 dipeptidase 1 increases expression ISO Isoproterenol results in increased expression of DPEP1 mRNA CTD PMID:20003209 NCBI chr19:51,209,831...51,237,004
Ensembl chr19:51,219,660...51,235,257 		JBrowse link
G Dpp7 dipeptidylpeptidase 7 increases expression ISO Isoproterenol results in increased expression of DPP7 mRNA CTD PMID:20003209 NCBI chr 3:8,165,091...8,169,343
Ensembl chr 3:8,165,091...8,169,355 		JBrowse link
G Dsg2 desmoglein 2 decreases expression ISO Isoproterenol results in decreased expression of DSG2 mRNA CTD PMID:20003209 NCBI chr18:11,846,207...11,904,630
Ensembl chr18:11,846,183...11,904,156 		JBrowse link
G Dtx4 deltex E3 ubiquitin ligase 4 increases expression ISO Isoproterenol results in increased expression of DTX4 mRNA CTD PMID:20003209 NCBI chr 1:209,457,719...209,545,163
Ensembl chr 1:209,460,735...209,492,818 		JBrowse link
G Dusp1 dual specificity phosphatase 1 multiple interactions ISO DUSP1 protein inhibits the reaction [Isoproterenol results in decreased expression of COL2A1 mRNA]; DUSP1 protein inhibits the reaction [Isoproterenol results in decreased expression of COL2A1 protein]; DUSP1 protein inhibits the reaction [Isoproterenol results in increased phosphorylation of MAPK1 protein]; DUSP1 protein inhibits the reaction [Isoproterenol results in increased phosphorylation of MAPK3 protein] CTD PMID:21177286 NCBI chr10:16,680,478...16,683,275 JBrowse link
G Dusp4 dual specificity phosphatase 4 increases expression ISO Isoproterenol results in increased expression of DUSP4 mRNA CTD PMID:20003209 NCBI chr16:57,376,659...57,398,161
Ensembl chr16:57,377,229...57,398,138 		JBrowse link
G Dusp5 dual specificity phosphatase 5 decreases expression EXP isoprenaline decreases expression of Dusp5 mRNA and protein in cardiac muscle cells RGD PMID:27318893 RGD:156430318 NCBI chr 1:252,538,408...252,555,320
Ensembl chr 1:252,538,449...252,551,818 		JBrowse link
G Dusp8 dual specificity phosphatase 8 decreases expression ISO Isoproterenol results in decreased expression of DUSP8 mRNA CTD PMID:20003209 NCBI chr 1:197,167,392...197,184,285
Ensembl chr 1:197,169,422...197,182,921 		JBrowse link
G Dxo decapping exoribonuclease increases expression ISO Isoproterenol results in increased expression of DXO mRNA CTD PMID:21335049 NCBI chr20:3,993,322...3,995,484
Ensembl chr20:3,993,327...3,995,494 		JBrowse link
G Ecm1 extracellular matrix protein 1 increases expression ISO Isoproterenol results in increased expression of ECM1 mRNA CTD PMID:20003209 NCBI chr 2:183,287,491...183,292,729
Ensembl chr 2:183,287,322...183,292,671 		JBrowse link
G Edem1 ER degradation enhancing alpha-mannosidase like protein 1 increases expression ISO Isoproterenol results in increased expression of EDEM1 mRNA CTD PMID:21335049 PMID:21823215 NCBI chr 4:141,797,631...141,829,717
Ensembl chr 4:141,797,701...141,829,717 		JBrowse link
G Edn1 endothelin 1 multiple interactions
increases activity
increases expression		 EXP Cyclosporine inhibits the reaction [Isoproterenol results in increased activity of EDN1 promoter]; Glyburide inhibits the reaction [natakalim inhibits the reaction [Isoproterenol results in increased expression of EDN1 mRNA]]; Glyburide inhibits the reaction [natakalim inhibits the reaction [Isoproterenol results in increased expression of EDN1 protein]]; N-(1-methylethyl)-1,1,2-trimethylpropylamine inhibits the reaction [Isoproterenol results in increased expression of EDN1 mRNA]; N-(1-methylethyl)-1,1,2-trimethylpropylamine inhibits the reaction [Isoproterenol results in increased expression of EDN1 protein]; natakalim inhibits the reaction [Isoproterenol results in increased expression of EDN1 mRNA]; natakalim inhibits the reaction [Isoproterenol results in increased expression of EDN1 protein]; Nifedipine inhibits the reaction [Isoproterenol results in increased activity of EDN1 promoter]
Isoproterenol results in increased expression of EDN1 mRNA; Isoproterenol results in increased expression of EDN1 protein		 CTD PMID:9861301 PMID:11435416 PMID:27174236 PMID:27890915 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885 		JBrowse link
G Ednra endothelin receptor type A increases expression
multiple interactions		 ISO
EXP		 Isoproterenol results in increased expression of EDNRA mRNA
Isoproterenol results in increased expression of EDNRA mRNA; Isoproterenol results in increased expression of EDNRA protein
CPU0213 inhibits the reaction [Isoproterenol results in increased expression of EDNRA mRNA]; CPU0213 inhibits the reaction [Isoproterenol results in increased expression of EDNRA protein]; natakalim inhibits the reaction [Isoproterenol results in increased expression of EDNRA protein]; pimagedine inhibits the reaction [Isoproterenol results in increased expression of EDNRA mRNA]		 CTD PMID:18594475 PMID:20003209 PMID:20307649 PMID:27174236 NCBI chr19:30,233,540...30,303,727
Ensembl chr19:30,233,571...30,297,049 		JBrowse link
G Ednrb endothelin receptor type B multiple interactions
increases expression		 EXP CPU0213 inhibits the reaction [Isoproterenol results in increased expression of EDNRB mRNA]; natakalim inhibits the reaction [Isoproterenol results in increased expression of EDNRB protein]
Isoproterenol results in increased expression of EDNRB mRNA; Isoproterenol results in increased expression of EDNRB protein		 CTD PMID:18594475 PMID:27174236 NCBI chr15:80,640,839...80,672,115
Ensembl chr15:80,643,043...80,672,115 		JBrowse link
G Eef1akmt1 EEF1A lysine methyltransferase 1 decreases expression ISO Isoproterenol results in decreased expression of EEF1AKMT1 mRNA CTD PMID:20003209 NCBI chr15:31,694,284...31,711,367
Ensembl chr15:31,694,292...31,711,336 		JBrowse link
G Efhd2 EF-hand domain family, member D2 increases expression ISO Isoproterenol results in increased expression of EFHD2 mRNA CTD PMID:20003209 NCBI chr 5:154,160,945...154,176,980
Ensembl chr 5:154,160,946...154,176,980 		JBrowse link
G Egfr epidermal growth factor receptor increases expression
multiple interactions		 ISO Isoproterenol results in increased expression of EGFR mRNA
Isoproterenol promotes the reaction [ADRB1 protein results in increased uptake of EGFR protein]		 CTD PMID:18787115 PMID:20003209 NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382 		JBrowse link
G Egr1 early growth response 1 multiple interactions
increases expression
decreases expression		 ISO
EXP		 EGR1 protein affects the reaction [[Isoproterenol co-treated with Phenylephrine] results in increased expression of SLC8A1 mRNA]; EGR1 protein affects the reaction [[Isoproterenol co-treated with Phenylephrine] results in increased expression of SLC8A1 protein]; EGR1 protein affects the reaction [[Phenylephrine co-treated with Isoproterenol] results in increased expression of ACTA1 mRNA]; EGR1 protein affects the reaction [[Phenylephrine co-treated with Isoproterenol] results in increased expression of JUN mRNA]; EGR1 protein affects the reaction [[Phenylephrine co-treated with Isoproterenol] results in increased expression of NAB2 mRNA]; EGR1 protein affects the reaction [[Phenylephrine co-treated with Isoproterenol] results in increased expression of NPPA mRNA]; EGR1 protein affects the reaction [[Phenylephrine co-treated with Isoproterenol] results in increased expression of SP1 mRNA]
Isoproterenol results in increased expression of EGR1 protein
4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [Isoproterenol results in increased expression of EGR1 protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Isoproterenol results in increased expression of EGR1 protein]; Propranolol inhibits the reaction [Isoproterenol results in increased expression of EGR1 protein]
Isoproterenol results in decreased expression of EGR1 mRNA		 CTD PMID:10710348 PMID:15621046 PMID:20003209 NCBI chr18:26,462,967...26,466,766
Ensembl chr18:26,462,981...26,466,766 		JBrowse link
G Eif1a eukaryotic translation initiation factor 1A increases expression ISO Isoproterenol results in increased expression of EIF1A mRNA CTD PMID:20003209 PMID:21335049 NCBI chr18:39,325,695...39,338,043
Ensembl chr18:39,325,202...39,338,696 		JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 increases expression ISO Isoproterenol results in increased expression of EIF2AK3 mRNA CTD PMID:21335049 NCBI chr 4:102,805,495...102,866,914
Ensembl chr 4:102,805,510...102,866,911 		JBrowse link
G Eif4a2 eukaryotic translation initiation factor 4A2 decreases expression ISO Isoproterenol results in decreased expression of EIF4A2 mRNA CTD PMID:21335049 NCBI chr11:77,764,126...77,770,810
Ensembl chr11:77,764,124...77,770,781 		JBrowse link
G Eif4e eukaryotic translation initiation factor 4E decreases expression ISO Isoproterenol results in decreased expression of EIF4E mRNA CTD PMID:20003209 NCBI chr 2:227,066,519...227,099,261
Ensembl chr 2:227,066,673...227,098,683 		JBrowse link
G Ell2 elongation factor for RNA polymerase II 2 increases expression ISO Isoproterenol results in increased expression of ELL2 mRNA CTD PMID:20003209 NCBI chr 2:5,189,375...5,258,781
Ensembl chr 2:5,189,971...5,258,781 		JBrowse link
G Eln elastin multiple interactions
increases expression		 EXP [Isoproterenol co-treated with Hydralazine] results in increased expression of ELN protein
Isoproterenol results in increased expression of ELN protein		 CTD PMID:3446201 NCBI chr12:21,968,544...22,011,929
Ensembl chr12:21,968,544...22,011,928 		JBrowse link
G Elovl1 ELOVL fatty acid elongase 1 increases expression ISO Isoproterenol results in increased expression of ELOVL1 mRNA CTD PMID:20003209 NCBI chr 5:131,961,478...131,965,961
Ensembl chr 5:131,961,322...131,965,958 		JBrowse link
G Elp1 elongator acetyltransferase complex subunit 1 multiple interactions EXP [Isoproterenol co-treated with POSTN protein] results in decreased expression of ELP1 mRNA CTD PMID:30303030 NCBI chr 5:71,453,338...71,505,833
Ensembl chr 5:71,456,310...71,505,762 		JBrowse link
G Enc1 ectodermal-neural cortex 1 increases expression ISO Isoproterenol results in increased expression of ENC1 mRNA CTD PMID:20003209 NCBI chr 2:28,550,670...28,562,591
Ensembl chr 2:28,550,464...28,562,713 		JBrowse link
G Eno1 enolase 1 decreases expression ISO Isoproterenol results in decreased expression of ENO1 mRNA CTD PMID:20003209 NCBI chr 5:160,719,951...160,731,337
Ensembl chr 5:160,719,951...160,731,336
Ensembl chr 3:160,719,951...160,731,336 		JBrowse link
G Enpp1 ectonucleotide pyrophosphatase/phosphodiesterase 1 decreases expression EXP Isoproterenol results in decreased expression of ENPP1 protein CTD PMID:21414308 NCBI chr 1:20,698,746...20,763,741
Ensembl chr 1:20,698,764...20,763,715 		JBrowse link
G Entpd1 ectonucleoside triphosphate diphosphohydrolase 1 increases expression ISO Isoproterenol results in increased expression of ENTPD1 mRNA CTD PMID:20003209 NCBI chr 1:239,425,515...239,552,323
Ensembl chr 1:239,425,430...239,552,317 		JBrowse link
G Eps8 EGFR pathway substrate 8, signaling adaptor increases expression ISO Isoproterenol results in increased expression of EPS8 mRNA CTD PMID:20003209 NCBI chr 4:170,388,378...170,486,873
Ensembl chr 4:170,388,378...170,486,873 		JBrowse link
G Ereg epiregulin increases expression ISO Isoproterenol results in increased expression of EREG mRNA CTD PMID:32816093 NCBI chr14:17,027,287...17,041,062
Ensembl chr14:17,027,287...17,041,062 		JBrowse link
G Erp29 endoplasmic reticulum protein 29 increases expression ISO Isoproterenol results in increased expression of ERP29 mRNA CTD PMID:21335049 NCBI chr12:35,089,698...35,095,952
Ensembl chr12:35,089,707...35,096,376 		JBrowse link
G Errfi1 ERBB receptor feedback inhibitor 1 increases expression ISO Isoproterenol results in increased expression of ERRFI1 mRNA CTD PMID:20003209 NCBI chr 5:161,323,981...161,337,289
Ensembl chr 5:161,323,998...161,337,282 		JBrowse link
G Etf1 eukaryotic translation termination factor 1 increases expression ISO Isoproterenol results in increased expression of ETF1 mRNA CTD PMID:20003209 NCBI chr18:26,502,413...26,530,753
Ensembl chr18:26,504,080...26,530,810 		JBrowse link
G Ezh1 enhancer of zeste 1 polycomb repressive complex 2 subunit increases expression ISO Isoproterenol results in increased expression of EZH1 mRNA CTD PMID:20003209 NCBI chr10:86,126,023...86,162,001
Ensembl chr10:86,126,015...86,161,921 		JBrowse link
G F13a1 coagulation factor XIII A1 chain increases expression ISO Isoproterenol results in increased expression of F13A1 mRNA CTD PMID:20003209 NCBI chr17:27,815,723...27,992,494
Ensembl chr17:27,815,702...27,992,700 		JBrowse link
G Fabp3 fatty acid binding protein 3 increases expression
decreases expression		 ISO
EXP		 Isoproterenol results in increased expression of FABP3 protein
Isoproterenol results in decreased expression of FABP3 protein		 CTD PMID:19549929 PMID:19826179 PMID:19854236 PMID:22878004 NCBI chr 5:142,651,962...142,658,707
Ensembl chr 5:142,651,956...142,658,718 		JBrowse link
G Fabp5 fatty acid binding protein 5 increases expression ISO Isoproterenol results in increased expression of FABP5 mRNA CTD PMID:21335049 NCBI chr 2:91,765,056...91,768,716
Ensembl chr 2:91,765,056...91,853,773 		JBrowse link
G Fam110d family with sequence similarity 110, member D increases expression ISO Isoproterenol results in increased expression of FAM110D mRNA CTD PMID:20003209 NCBI chr 5:146,471,048...146,474,019
Ensembl chr 5:146,471,049...146,474,056 		JBrowse link
G Fam117b family with sequence similarity 117, member B increases expression ISO Isoproterenol results in increased expression of FAM117B mRNA CTD PMID:20003209 NCBI chr 9:61,340,284...61,418,531
Ensembl chr 9:61,340,249...61,408,483 		JBrowse link
G Farp1 FERM, ARH/RhoGEF and pleckstrin domain protein 1 increases expression ISO Isoproterenol results in increased expression of FARP1 mRNA CTD PMID:21335049 NCBI chr15:98,124,304...98,363,299
Ensembl chr15:98,182,329...98,363,299 		JBrowse link
G Fas Fas cell surface death receptor increases expression
multiple interactions		 ISO
EXP		 Isoproterenol results in increased expression of FAS mRNA
Apigenin inhibits the reaction [Isoproterenol results in increased expression of FAS protein]; caryophyllene inhibits the reaction [Isoproterenol results in increased expression of FAS mRNA]; Thymol inhibits the reaction [Isoproterenol results in increased expression of FAS mRNA]; Vanillic Acid inhibits the reaction [Isoproterenol results in increased expression of FAS mRNA]
Isoproterenol results in increased expression of FAS mRNA; Isoproterenol results in increased expression of FAS protein		 CTD PMID:11218852 PMID:20003209 PMID:24286936 PMID:25794854 PMID:26996544 More... NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591 		JBrowse link
G Faslg Fas ligand increases expression EXP Isoproterenol results in increased expression of FASLG protein CTD PMID:19001025 NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215 		JBrowse link
G Fblim1 filamin binding LIM protein 1 decreases expression ISO Isoproterenol results in decreased expression of FBLIM1 mRNA CTD PMID:20003209 NCBI chr 5:153,883,945...153,915,524
Ensembl chr 5:153,883,960...153,913,757 		JBrowse link
G Fbln2 fibulin 2 increases expression ISO Isoproterenol results in increased expression of FBLN2 mRNA CTD PMID:20003209 NCBI chr 4:123,704,289...123,763,857
Ensembl chr 4:123,704,373...123,763,948 		JBrowse link
G Fbxl20 F-box and leucine-rich repeat protein 20 increases expression ISO Isoproterenol results in increased expression of FBXL20 mRNA CTD PMID:20003209 NCBI chr10:83,080,568...83,143,680
Ensembl chr10:83,086,551...83,144,162 		JBrowse link
G Fbxo31 F-box protein 31 increases expression ISO Isoproterenol results in increased expression of FBXO31 mRNA CTD PMID:20003209 NCBI chr19:49,624,813...49,656,052
Ensembl chr19:49,627,686...49,656,010 		JBrowse link
G Fbxo32 F-box protein 32 increases expression ISO Isoproterenol results in increased expression of FBXO32 mRNA CTD PMID:20003209 NCBI chr 7:89,731,428...89,764,997
Ensembl chr 7:89,730,232...89,765,436 		JBrowse link
G Fbxo9 f-box protein 9 decreases expression ISO Isoproterenol results in decreased expression of FBXO9 mRNA CTD PMID:21335049 NCBI chr 8:78,958,482...78,984,015
Ensembl chr 8:78,958,483...78,983,949 		JBrowse link
G Fbxw7 F-box and WD repeat domain containing 7 decreases expression ISO Isoproterenol results in decreased expression of FBXW7 mRNA CTD PMID:20003209 NCBI chr 2:170,149,706...170,311,536
Ensembl chr 2:170,149,694...170,309,941 		JBrowse link
G Fcgr2a Fc gamma receptor 2A increases expression ISO Isoproterenol results in increased expression of FCGR3 mRNA CTD PMID:20003209 NCBI chr13:83,280,782...83,297,535
Ensembl chr13:83,280,784...83,295,967 		JBrowse link
G Fcgr2b Fc gamma receptor 2B increases expression EXP
ISO		 Isoproterenol results in increased expression of FCGR2B mRNA CTD PMID:20003209 PMID:20211217 NCBI chr13:83,191,253...83,207,778
Ensembl chr13:83,193,163...83,207,778 		JBrowse link
G Fcgr3a Fc gamma receptor 3A increases expression ISO Isoproterenol results in increased expression of FCGR4 mRNA CTD PMID:20003209 NCBI chr13:83,249,905...83,259,921
Ensembl chr13:83,249,872...83,259,921 		JBrowse link
G Fen1 flap structure-specific endonuclease 1 increases expression ISO Isoproterenol results in increased expression of FEN1 mRNA CTD PMID:21335049 NCBI chr 1:206,845,126...206,849,821
Ensembl chr 1:206,844,884...206,850,003 		JBrowse link
G Fetub fetuin B increases expression ISO Isoproterenol results in increased expression of FETUB mRNA CTD PMID:20003209 NCBI chr11:78,082,158...78,093,022
Ensembl chr11:78,082,156...78,095,135 		JBrowse link
G Fgf16 fibroblast growth factor 16 decreases expression ISO Isoproterenol results in decreased expression of FGF16 mRNA CTD PMID:20003209 NCBI chr  X:70,816,658...70,828,028
Ensembl chr  X:70,817,433...70,878,717 		JBrowse link
G Fgfr3 fibroblast growth factor receptor 3 increases expression ISO Isoproterenol results in increased expression of FGFR3 mRNA CTD PMID:20003209 NCBI chr14:76,987,242...77,002,671
Ensembl chr14:76,987,993...77,003,341 		JBrowse link
G Fhl1 four and a half LIM domains 1 decreases expression
increases expression		 ISO
EXP		 Isoproterenol results in decreased expression of FHL1 mRNA
Isoproterenol results in increased expression of FHL1 mRNA		 CTD PMID:20211217 PMID:23558518 PMID:24286936 NCBI chr  X:134,555,399...134,614,930
Ensembl chr  X:134,555,479...134,614,928 		JBrowse link
G Fis1 fission, mitochondrial 1 increases expression EXP Isoproterenol results in increased expression of FIS1 protein CTD PMID:27491814 NCBI chr12:19,708,560...19,723,392
Ensembl chr12:19,708,558...19,723,377 		JBrowse link
G Fkbp1b FKBP prolyl isomerase 1B multiple interactions
decreases expression		 EXP 1-(methanesulfonamido-1-naphthyloxy)-2-(N-(4-methane sulfonamidophenethyl)-N-acetamido)ethane inhibits the reaction [Isoproterenol results in decreased expression of FKBP1B mRNA]; 1-(methanesulfonamido-1-naphthyloxy)-2-(N-(4-methane sulfonamidophenethyl)-N-acetamido)ethane inhibits the reaction [Isoproterenol results in decreased expression of FKBP1B protein]; dofetilide inhibits the reaction [Isoproterenol results in decreased expression of FKBP1B mRNA]; dofetilide inhibits the reaction [Isoproterenol results in decreased expression of FKBP1B protein]
Isoproterenol results in decreased expression of FKBP1B mRNA; Isoproterenol results in decreased expression of FKBP1B protein		 CTD PMID:20723002 NCBI chr 6:27,832,128...27,850,600
Ensembl chr 6:27,838,802...27,848,653 		JBrowse link
G Fkbp4 FKBP prolyl isomerase 4 decreases expression ISO Isoproterenol results in decreased expression of FKBP4 mRNA CTD PMID:20003209 NCBI chr 4:161,703,379...161,711,833
Ensembl chr 4:161,703,379...161,711,833 		JBrowse link
G Fkbp5 FKBP prolyl isomerase 5 increases expression ISO Isoproterenol results in increased expression of FKBP5 mRNA CTD PMID:20003209 NCBI chr20:6,457,207...6,575,404
Ensembl chr20:6,457,216...6,541,674 		JBrowse link
G Flt1 Fms related receptor tyrosine kinase 1 increases expression ISO Isoproterenol results in increased expression of FLT1 mRNA CTD PMID:20003209 NCBI chr12:7,296,899...7,468,626
Ensembl chr12:7,297,292...7,468,626 		JBrowse link
G Fmo1 flavin containing dimethylaniline monoxygenase 1 increases expression ISO Isoproterenol results in increased expression of FMO1 mRNA CTD PMID:20003209 NCBI chr13:75,182,184...75,214,439
Ensembl chr13:75,182,176...75,214,647 		JBrowse link
G Fmo2 flavin containing dimethylaniline monoxygenase 2 increases expression ISO Isoproterenol results in increased expression of FMO2 mRNA CTD PMID:20003209 NCBI chr13:75,221,149...75,244,377
Ensembl chr13:75,224,402...75,244,308 		JBrowse link
G Fn1 fibronectin 1 decreases expression
increases expression
multiple interactions		 ISO
EXP		 Isoproterenol results in decreased expression of FN1 protein
Isoproterenol results in increased expression of FN1 protein
Glyburide promotes the reaction [Isoproterenol results in increased expression of FN1 protein]; pyrvinium inhibits the reaction [Glyburide promotes the reaction [Isoproterenol results in increased expression of FN1 protein]]; pyrvinium inhibits the reaction [Isoproterenol results in increased expression of FN1 protein]; Quercetin inhibits the reaction [Isoproterenol results in increased expression of FN1 protein]; Rutin inhibits the reaction [Isoproterenol results in increased expression of FN1 protein]
Isoproterenol results in increased expression of FN1 mRNA		 CTD PMID:11821714 PMID:20003209 PMID:24117263 PMID:35305975 NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions
increases expression		 ISO
EXP		 [N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide co-treated with U 0126] inhibits the reaction [Isoproterenol results in increased expression of FOS mRNA]; [Phenylephrine co-treated with Isoproterenol] results in increased expression of FOS mRNA; Doxycycline inhibits the reaction [Isoproterenol results in increased expression of FOS mRNA]; U 0126 inhibits the reaction [Isoproterenol results in increased expression of FOS mRNA]
Isoproterenol results in increased expression of FOS mRNA; Isoproterenol results in increased expression of FOS protein
Isoproterenol results in increased expression of FOS; Isoproterenol results in increased expression of FOS mRNA
CREM protein inhibits the reaction [Isoproterenol results in increased expression of FOS mRNA]; Isoproterenol promotes the reaction [JUN protein binds to FOS protein]; Propranolol inhibits the reaction [Isoproterenol results in increased expression of FOS]		 CTD PMID:7544033 PMID:7905536 PMID:10710348 PMID:12791704 PMID:14764439 More... NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036 		JBrowse link
G Fosb FosB proto-oncogene, AP-1 transcription factor subunit increases expression EXP Isoproterenol results in increased expression of FOSB CTD PMID:7905536 NCBI chr 1:78,954,312...78,961,492
Ensembl chr 1:78,954,115...78,961,465 		JBrowse link
G Fosl1 FOS like 1, AP-1 transcription factor subunit increases expression
multiple interactions		 EXP
ISO		 Isoproterenol results in increased expression of FOSL1 mRNA
[N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide co-treated with U 0126] inhibits the reaction [Isoproterenol results in increased expression of FOSL1 mRNA]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Isoproterenol results in increased expression of FOSL1 mRNA]; U 0126 inhibits the reaction [Isoproterenol results in increased expression of FOSL1 mRNA]
Isoproterenol results in increased expression of FOSL1 mRNA; Isoproterenol results in increased expression of FOSL1 protein		 CTD PMID:20211217 PMID:21177286 NCBI chr 1:202,754,549...202,763,057
Ensembl chr 1:202,754,529...202,764,930 		JBrowse link
G Fosl2 FOS like 2, AP-1 transcription factor subunit increases expression
multiple interactions		 ISO Isoproterenol results in increased expression of FOSL2 mRNA; Isoproterenol results in increased expression of FOSL2 protein
[N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide co-treated with U 0126] inhibits the reaction [Isoproterenol results in increased expression of FOSL2 mRNA]; U 0126 inhibits the reaction [Isoproterenol results in increased expression of FOSL2 mRNA]		 CTD PMID:21177286 NCBI chr 6:24,297,898...24,319,219
Ensembl chr 6:24,300,956...24,320,034 		JBrowse link
G Foxo1 forkhead box O1 increases phosphorylation ISO Isoproterenol results in increased phosphorylation of FOXO1 protein CTD PMID:15618457 NCBI chr 2:136,312,168...136,390,603
Ensembl chr 2:136,312,168...136,387,790 		JBrowse link
G Foxo3 forkhead box O3 increases expression ISO Isoproterenol results in increased expression of FOXO3 mRNA CTD PMID:20003209 NCBI chr20:45,669,708...45,764,606
Ensembl chr20:45,672,995...45,764,561 		JBrowse link
G Fry FRY microtubule binding protein increases expression ISO Isoproterenol results in increased expression of FRY mRNA CTD PMID:20003209 NCBI chr12:4,493,890...4,887,118
Ensembl chr12:4,493,891...4,799,116 		JBrowse link
G Fshb follicle stimulating hormone subunit beta multiple interactions
increases expression		 EXP CPU0213 inhibits the reaction [Isoproterenol results in increased expression of FSHB protein] CTD PMID:20307649 NCBI chr 3:93,548,560...93,552,370
Ensembl chr 3:93,548,560...93,552,370 		JBrowse link
G Ftl1 ferritin light chain 1 increases expression ISO Isoproterenol results in increased expression of FTL1 mRNA CTD PMID:20003209 NCBI chr 1:95,936,387...95,938,234
Ensembl chr 1:95,936,387...95,939,725
Ensembl chr10:95,936,387...95,939,725
Ensembl chr 2:95,936,387...95,939,725 		JBrowse link
G Fus Fus RNA binding protein decreases expression ISO Isoproterenol results in decreased expression of FUS mRNA CTD PMID:20003209 NCBI chr 1:182,576,479...182,590,417
Ensembl chr 1:182,576,545...182,590,414 		JBrowse link
G G3bp2 G3BP stress granule assembly factor 2 multiple interactions
increases expression		 EXP G3BP2 protein promotes the reaction [Isoproterenol results in increased expression of MYH7 mRNA]; G3BP2 protein promotes the reaction [Isoproterenol results in increased expression of MYH7 protein]; G3BP2 protein promotes the reaction [Isoproterenol results in increased expression of NPPA mRNA]; G3BP2 protein promotes the reaction [Isoproterenol results in increased expression of NPPA protein]; G3BP2 protein promotes the reaction [Isoproterenol results in increased expression of NPPB mRNA]; G3BP2 protein promotes the reaction [Isoproterenol results in increased expression of NPPB protein]; Isoproterenol promotes the reaction [G3BP2 protein binds to NFKBIA protein]
Isoproterenol results in increased expression of G3BP2 mRNA; Isoproterenol results in increased expression of G3BP2 protein		 CTD PMID:28816235 NCBI chr14:15,932,403...16,020,555
Ensembl chr14:15,987,417...16,020,548 		JBrowse link
G G6pd glucose-6-phosphate dehydrogenase multiple interactions
increases activity		 EXP Atenolol inhibits the reaction [Isoproterenol results in increased activity of G6PD protein]; Cycloheximide inhibits the reaction [Isoproterenol results in increased activity of G6PD protein]; Dactinomycin inhibits the reaction [Isoproterenol results in increased activity of G6PD protein]; Gallopamil inhibits the reaction [Isoproterenol results in increased activity of G6PD protein] CTD PMID:1978808 NCBI chr  X:152,201,081...152,220,863
Ensembl chr  X:152,201,098...152,220,801 		JBrowse link
G Gabarapl1 GABA type A receptor associated protein like 1 increases expression ISO Isoproterenol results in increased expression of GABARAPL1 mRNA CTD PMID:20003209 NCBI chr 4:162,980,309...162,989,452
Ensembl chr 4:162,980,249...162,989,450 		JBrowse link
G Gadd45g growth arrest and DNA-damage-inducible, gamma increases expression ISO Isoproterenol results in increased expression of GADD45G mRNA CTD PMID:21823215 NCBI chr17:13,376,842...13,378,587
Ensembl chr17:13,376,839...13,378,610 		JBrowse link
G Gal galanin and GMAP prepropeptide multiple interactions
increases activity
increases expression
decreases activity		 EXP [ferulic acid co-treated with Ascorbic Acid] inhibits the reaction [Isoproterenol results in increased activity of GAL protein]; [Nicorandil co-treated with Amlodipine] inhibits the reaction [Isoproterenol results in decreased activity of GAL protein]; [Nicorandil co-treated with Amlodipine] inhibits the reaction [Isoproterenol results in increased activity of GAL protein]; Betaine inhibits the reaction [Isoproterenol results in decreased activity of GAL protein]; Betaine inhibits the reaction [Isoproterenol results in increased activity of GAL protein]; naringin inhibits the reaction [Isoproterenol results in increased activity of GAL protein]; S-allylcysteine inhibits the reaction [Isoproterenol results in increased expression of GAL mRNA] CTD PMID:2015110 PMID:11829124 PMID:14499179 PMID:17045618 PMID:17182065 More... NCBI chr 1:200,650,439...200,655,302
Ensembl chr 1:200,650,439...200,654,959 		JBrowse link
G Galnt15 polypeptide N-acetylgalactosaminyltransferase 15 increases expression ISO Isoproterenol results in increased expression of GALNT15 mRNA CTD PMID:20003209 NCBI chr16:7,227,232...7,267,002
Ensembl chr16:7,227,271...7,267,014 		JBrowse link
G Gas5 growth arrest specific 5 increases expression
decreases expression		 ISO
EXP		 Isoproterenol results in increased expression of GAS5 mRNA
Isoproterenol results in decreased expression of GAS5 mRNA		 CTD PMID:20003209 PMID:28526319 NCBI chr13:73,303,611...73,306,932 JBrowse link
G Gas6 growth arrest specific 6 multiple interactions
decreases expression		 EXP natakalim inhibits the reaction [Isoproterenol results in decreased expression of GAS6 protein] CTD PMID:27890915 NCBI chr16:76,045,430...76,075,904
Ensembl chr16:76,045,426...76,075,904 		JBrowse link
G Gata4 GATA binding protein 4 multiple interactions ISO
EXP		 [Phenylephrine co-treated with Isoproterenol] results in increased expression of GATA4 mRNA
Isoproterenol promotes the reaction [NFATC1 protein binds to GATA4 protein]		 CTD PMID:10710348 PMID:11435416 NCBI chr15:37,459,601...37,531,291
Ensembl chr15:37,459,601...37,505,636 		JBrowse link
G Gbp6 guanylate binding protein family member 6 increases expression ISO Isoproterenol results in increased expression of GBP6 mRNA CTD PMID:20003209 NCBI chr14:4,730,286...4,756,508
Ensembl chr14:4,730,453...4,839,062
Ensembl chr14:4,730,453...4,839,062 		JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit decreases expression ISO Isoproterenol results in decreased expression of GCLC mRNA CTD PMID:21335049 NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544 		JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit increases expression
multiple interactions
decreases expression		 ISO
EXP		 Isoproterenol results in increased expression of GCLM mRNA
[Isoproterenol co-treated with POSTN protein] results in decreased expression of GCLM mRNA
Isoproterenol results in decreased expression of GCLM mRNA		 CTD PMID:20003209 PMID:21335049 PMID:30303030 NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535 		JBrowse link
G Gcnt2 glucosaminyl (N-acetyl) transferase 2 increases expression ISO Isoproterenol results in increased expression of GCNT2 mRNA CTD PMID:20003209 NCBI chr17:23,796,859...23,901,625
Ensembl chr17:23,796,859...23,901,611 		JBrowse link
G Gda guanine deaminase increases expression ISO Isoproterenol results in increased expression of GDA mRNA CTD PMID:20003209 NCBI chr 1:218,903,045...218,982,360
Ensembl chr 1:218,906,815...218,982,416 		JBrowse link
G Gem GTP binding protein overexpressed in skeletal muscle multiple interactions
increases expression		 ISO Doxycycline inhibits the reaction [Isoproterenol results in increased expression of GEM mRNA] CTD PMID:18089841 NCBI chr 5:25,214,309...25,225,222
Ensembl chr 5:25,214,309...25,225,222 		JBrowse link
G Gfpt2 glutamine-fructose-6-phosphate transaminase 2 increases expression ISO Isoproterenol results in increased expression of GFPT2 mRNA CTD PMID:20003209 NCBI chr10:34,115,005...34,161,329
Ensembl chr10:34,115,052...34,161,329 		JBrowse link
G Ggt5 gamma-glutamyltransferase 5 increases expression ISO Isoproterenol results in increased expression of GGT5 mRNA CTD PMID:20003209 NCBI chr20:13,043,255...13,071,523
Ensembl chr20:13,043,257...13,071,450 		JBrowse link
G Ghrl ghrelin and obestatin prepropeptide increases expression EXP Isoproterenol results in increased expression of GHRL protein CTD PMID:20572026 NCBI chr 4:146,865,712...146,869,621
Ensembl chr 4:146,865,712...146,869,621 		JBrowse link
G Ghsr growth hormone secretagogue receptor increases expression EXP Isoproterenol results in increased expression of GHSR mRNA; Isoproterenol results in increased expression of GHSR protein CTD PMID:20572026 NCBI chr 2:110,268,489...110,271,865
Ensembl chr 2:110,268,489...110,271,865 		JBrowse link
G Gigyf2 GRB10 interacting GYF protein 2 increases expression ISO Isoproterenol results in increased expression of GIGYF2 mRNA CTD PMID:20003209 NCBI chr 9:88,001,212...88,127,040
Ensembl chr 9:88,001,301...88,125,715 		JBrowse link
G Gja1 gap junction protein, alpha 1 multiple interactions
decreases expression
increases expression		 EXP
ISO		 [Isoproterenol co-treated with Metoprolol] results in increased expression of GJA1 protein
Isoproterenol results in decreased expression of GJA1 mRNA
Isoproterenol results in increased expression of GJA1 mRNA; Isoproterenol results in increased expression of GJA1 protein
Doxycycline inhibits the reaction [Isoproterenol results in decreased expression of GJA1 mRNA]		 CTD PMID:16352648 PMID:18089841 PMID:20003209 PMID:20215810 NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582 		JBrowse link
G Gk glycerol kinase increases activity EXP Isoproterenol results in increased activity of GK protein CTD PMID:12736183 NCBI chr  X:50,162,089...50,238,707
Ensembl chr  X:50,163,123...50,238,631 		JBrowse link
G Gla galactosidase, alpha multiple interactions
increases activity		 EXP Arbutin inhibits the reaction [Isoproterenol results in increased activity of GLA protein] CTD PMID:32757845 NCBI chr  X:97,769,227...97,780,646
Ensembl chr  X:97,768,996...97,780,664 		JBrowse link
G Glb1 galactosidase, beta 1 multiple interactions
increases activity
affects activity		 EXP Arbutin inhibits the reaction [Isoproterenol results in increased activity of GLB1 protein]; caffeic acid inhibits the reaction [Isoproterenol affects the activity of GLB1 protein]; Phytic Acid inhibits the reaction [Isoproterenol results in increased activity of GLB1 protein] CTD PMID:20391626 PMID:25560919 PMID:32757845 NCBI chr 8:114,085,508...114,158,127
Ensembl chr 8:114,085,508...114,158,127 		JBrowse link
G Glg1 golgi glycoprotein 1 multiple interactions EXP [Isoproterenol co-treated with POSTN protein] results in decreased expression of GLG1 mRNA CTD PMID:30303030 NCBI chr19:39,124,892...39,224,178
Ensembl chr19:39,124,641...39,224,178 		JBrowse link
G Glul glutamate-ammonia ligase increases expression ISO Isoproterenol results in increased expression of GLUL mRNA CTD PMID:20003209 NCBI chr13:65,969,053...66,035,121
Ensembl chr13:66,025,630...66,035,108 		JBrowse link
G Gna15 G protein subunit alpha 15 multiple interactions
increases response to substance		 ISO [GNA15 protein results in increased susceptibility to Isoproterenol] which results in increased activity of ADRB2 protein CTD PMID:9875846 NCBI chr 7:8,184,632...8,205,508
Ensembl chr 7:8,184,861...8,205,508 		JBrowse link
G Gnal G protein subunit alpha L increases response to substance
multiple interactions		 ISO GNAL protein results in increased susceptibility to Isoproterenol
Egtazic Acid inhibits the reaction [GNAL protein results in increased susceptibility to Isoproterenol]		 CTD PMID:15598656 NCBI chr18:60,622,311...60,762,599
Ensembl chr18:60,622,311...60,762,599 		JBrowse link
G Gnas GNAS complex locus multiple interactions
increases palmitoylation
increases response to substance		 EXP
ISO		 GNAS protein affects the susceptibility to [Potassium Chloride co-treated with Isoproterenol]; Isoproterenol affects the expression of and affects the localization of GNAS protein; Propranolol inhibits the reaction [Isoproterenol results in increased palmitoylation of GNAS protein]
Egtazic Acid inhibits the reaction [GNAS protein results in increased susceptibility to Isoproterenol]		 CTD PMID:9732414 PMID:10696522 PMID:12376418 PMID:15598656 NCBI chr 3:163,071,003...163,136,350
Ensembl chr 3:163,071,417...163,127,262
Ensembl chr 3:163,071,417...163,127,262 		JBrowse link
G Gng2 G protein subunit gamma 2 increases expression ISO Isoproterenol results in increased expression of GNG2 mRNA CTD PMID:20003209 NCBI chr15:4,316,038...4,416,918
Ensembl chr15:4,316,059...4,417,183 		JBrowse link
G Gng3 G protein subunit gamma 3 multiple interactions EXP [Isoproterenol co-treated with Atorvastatin] affects the localization of GNG3 protein CTD PMID:19136528 NCBI chr 1:205,731,837...205,733,603
Ensembl chr 1:205,731,837...205,733,603 		JBrowse link
G Gns glucosamine (N-acetyl)-6-sulfatase increases expression ISO Isoproterenol results in increased expression of GNS mRNA CTD PMID:20003209 NCBI chr 7:56,889,148...56,923,173
Ensembl chr 7:56,889,232...56,923,151 		JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1 multiple interactions
increases expression		 EXP
ISO		 Carvedilol inhibits the reaction [Isoproterenol results in increased expression of and results in increased secretion of GOT1 protein]; imetit inhibits the reaction [Isoproterenol results in increased expression of and results in increased secretion of GOT1 protein]; Isoproterenol results in increased expression of and results in increased secretion of GOT1 protein
Isoproterenol results in increased expression of GOT1 protein		 CTD PMID:25496245 PMID:38369011 NCBI chr 1:242,357,293...242,381,535
Ensembl chr 1:242,357,306...242,380,633 		JBrowse link
G Got2 glutamic-oxaloacetic transaminase 2 decreases expression EXP Isoproterenol results in decreased expression of GOT2 protein CTD PMID:19826179 NCBI chr19:9,174,304...9,199,995
Ensembl chr19:9,174,311...9,199,994 		JBrowse link
G Gpam glycerol-3-phosphate acyltransferase, mitochondrial decreases expression ISO Isoproterenol results in decreased expression of GPAM mRNA CTD PMID:21335049 NCBI chr 1:254,106,323...254,170,755
Ensembl chr 1:254,106,331...254,142,639 		JBrowse link
G Gpcpd1 glycerophosphocholine phosphodiesterase 1 decreases expression ISO Isoproterenol results in decreased expression of GPCPD1 mRNA CTD PMID:20003209 NCBI chr 3:119,787,681...119,832,550
Ensembl chr 3:119,787,682...119,832,517 		JBrowse link
G Gpihbp1 glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1 increases expression ISO Isoproterenol results in increased expression of GPIHBP1 mRNA CTD PMID:20003209 NCBI chr 7:107,285,584...107,288,702
Ensembl chr 7:107,285,654...107,288,702 		JBrowse link
G Gpnmb glycoprotein nmb increases expression ISO Isoproterenol results in increased expression of GPNMB mRNA CTD PMID:20003209 NCBI chr 4:78,010,247...78,031,491
Ensembl chr 4:78,010,197...78,049,367 		JBrowse link
G Gpr160 G protein-coupled receptor 160 increases expression ISO Isoproterenol results in increased expression of GPR160 mRNA CTD PMID:20003209 NCBI chr 2:112,483,364...112,563,072
Ensembl chr 2:112,484,935...112,563,148 		JBrowse link
G Gpr182 G protein-coupled receptor 182 increases expression ISO Isoproterenol results in increased expression of GPR182 mRNA CTD PMID:20003209 NCBI chr 7:63,585,997...63,589,088
Ensembl chr 7:63,578,750...63,589,210 		JBrowse link
G Gpt glutamic--pyruvic transaminase increases activity
multiple interactions		 EXP Isoproterenol results in increased activity of GPT protein
Carvedilol inhibits the reaction [Isoproterenol results in increased expression of and results in increased secretion of GPT protein]; imetit inhibits the reaction [Isoproterenol results in increased expression of and results in increased secretion of GPT protein]; Isoproterenol results in increased expression of and results in increased secretion of GPT protein; oleuropein inhibits the reaction [Isoproterenol results in increased expression of and results in increased secretion of GPT protein]		 CTD PMID:25496245 PMID:26056852 PMID:35130744 NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494 		JBrowse link
G Gpx1 glutathione peroxidase 1 multiple interactions
decreases activity		 EXP [Isoproterenol co-treated with POSTN protein] results in decreased expression of GPX1 mRNA; benidipine inhibits the reaction [Isoproterenol results in decreased activity of GPX1 protein] CTD PMID:25269373 PMID:30303030 NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024 		JBrowse link
G Gpx3 glutathione peroxidase 3 increases expression ISO Isoproterenol results in increased expression of GPX3 mRNA CTD PMID:20003209 NCBI chr10:39,028,624...39,036,695
Ensembl chr10:39,028,570...39,037,035 		JBrowse link
G Grina glutamate ionotropic receptor NMDA type subunit associated protein 1 increases expression ISO Isoproterenol results in increased expression of GRINA mRNA CTD PMID:20003209 NCBI chr 7:107,962,194...107,965,372
Ensembl chr 7:107,962,207...107,965,366 		JBrowse link
G Grk2 G protein-coupled receptor kinase 2 increases expression
multiple interactions		 EXP
ISO		 Isoproterenol results in increased expression of GRK2 mRNA
Isoproterenol results in increased expression of GRK2 mRNA; Isoproterenol results in increased expression of GRK2 protein
AGT affects the reaction [Isoproterenol results in decreased expression of GRK2 mRNA]		 CTD PMID:9788834 PMID:16731636 NCBI chr 1:201,580,823...201,601,580
Ensembl chr 1:201,581,480...201,601,582 		JBrowse link
G Grk5 G protein-coupled receptor kinase 5 increases expression ISO Isoproterenol results in increased expression of GRK5 mRNA CTD PMID:20003209 NCBI chr 1:260,028,269...260,223,699
Ensembl chr 1:260,028,242...260,218,701 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta multiple interactions
increases phosphorylation
decreases phosphorylation		 EXP
ISO		 2-((2-piperidin-1-ylethyl)thio)quinazolin-4(3H)-one inhibits the reaction [Isoproterenol results in decreased phosphorylation of GSK3B protein]; 2-((2-piperidin-1-ylethyl)thio)quinazolin-4(3H)-one inhibits the reaction [Isoproterenol results in increased phosphorylation of GSK3B protein]; 2-((2-piperidin-1-ylethyl)thio)quinazolin-4(3H)-one promotes the reaction [Isoproterenol results in increased phosphorylation of GSK3B protein]; Enalapril inhibits the reaction [Isoproterenol results in decreased phosphorylation of GSK3B protein]; plantamajoside inhibits the reaction [Isoproterenol results in increased phosphorylation of GSK3B protein]; Valsartan inhibits the reaction [Isoproterenol results in increased phosphorylation of GSK3B protein] CTD PMID:15951400 PMID:16716347 PMID:18806606 PMID:31009642 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646 		JBrowse link
G Gsr glutathione-disulfide reductase multiple interactions
decreases activity
increases activity
decreases expression		 EXP abana inhibits the reaction [Isoproterenol results in decreased expression of GSR]; allyl sulfide inhibits the reaction [Isoproterenol results in decreased activity of GSR protein]; benidipine inhibits the reaction [Isoproterenol results in decreased activity of GSR protein]; Catechin inhibits the reaction [Isoproterenol results in decreased activity of GSR protein]; Desmodium gangeticum extract inhibits the reaction [Isoproterenol results in decreased activity of GSR protein]; dicarbine inhibits the reaction [Isoproterenol results in increased activity of GSR protein]; Gallic Acid inhibits the reaction [Isoproterenol results in decreased expression of GSR protein]; mangiferin inhibits the reaction [Isoproterenol results in decreased activity of GSR protein]; protocatechuic acid inhibits the reaction [Isoproterenol results in decreased activity of GSR protein]; S-allylcysteine inhibits the reaction [Isoproterenol results in decreased activity of GSR protein]; Tretinoin inhibits the reaction [Isoproterenol results in decreased activity of GSR protein]
Isoproterenol results in decreased expression of GSR; Isoproterenol results in decreased expression of GSR protein		 CTD PMID:1840475 PMID:12557918 PMID:15261977 PMID:15740881 PMID:16697266 More... NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661 		JBrowse link
G Gsta1 glutathione S-transferase alpha 1 decreases activity
multiple interactions		 EXP Isoproterenol results in decreased activity of GSTA1 protein
benidipine inhibits the reaction [Isoproterenol results in decreased activity of GSTA1 protein]		 CTD PMID:25269373 NCBI chr 9:23,703,476...23,720,121
Ensembl chr 9:23,703,477...23,720,121 		JBrowse link
G Gsto1 glutathione S-transferase omega 1 decreases expression ISO Isoproterenol results in decreased expression of GSTO1 mRNA CTD PMID:21335049 NCBI chr 1:246,721,089...246,731,228
Ensembl chr 1:246,721,221...246,731,468 		JBrowse link
G Gtf2a1 general transcription factor 2A subunit 1 increases expression ISO Isoproterenol results in increased expression of GTF2A1 mRNA CTD PMID:20003209 NCBI chr 6:110,488,891...110,521,502
Ensembl chr 6:110,488,931...110,521,511 		JBrowse link
G Gusb glucuronidase, beta multiple interactions
increases activity
decreases activity
increases expression		 EXP [ferulic acid co-treated with Ascorbic Acid] inhibits the reaction [Isoproterenol results in increased activity of GUSB protein]; [Nicorandil co-treated with Amlodipine] inhibits the reaction [Isoproterenol results in increased activity of GUSB protein]; Arbutin inhibits the reaction [Isoproterenol results in increased activity of GUSB protein]; Betaine inhibits the reaction [Isoproterenol results in decreased activity of GUSB protein]; Betaine inhibits the reaction [Isoproterenol results in increased activity of GUSB protein]; caffeic acid inhibits the reaction [Isoproterenol results in increased activity of GUSB protein]; Curcumin inhibits the reaction [Isoproterenol results in increased activity of GUSB protein]; Ellagic Acid inhibits the reaction [Isoproterenol results in increased activity of GUSB protein]; epigallocatechin gallate inhibits the reaction [Isoproterenol results in increased activity of GUSB protein]; mangiferin inhibits the reaction [Isoproterenol results in decreased activity of GUSB protein]; naringin inhibits the reaction [Isoproterenol results in decreased activity of GUSB protein]; naringin inhibits the reaction [Isoproterenol results in increased activity of GUSB protein]; Phytic Acid inhibits the reaction [Isoproterenol results in increased activity of GUSB protein]; S-allylcysteine inhibits the reaction [Isoproterenol results in increased expression of GUSB mRNA] CTD PMID:2015110 PMID:8534267 PMID:11829124 PMID:14499179 PMID:17045618 More... NCBI chr12:26,701,188...26,714,718
Ensembl chr12:26,697,951...26,726,905 		JBrowse link
G H19 H19 imprinted maternally expressed transcript increases expression
increases expression 		ISO
EXP		 Isoproterenol results in increased expression of H19 mRNA
isoprenaline increases expression of H19 RNA in cardiac muscle cells		 CTD
RGD		 PMID:20003209 PMID:27318893 RGD:156430318 NCBI chr 1:197,730,698...197,733,374
Ensembl chr 1:197,730,698...197,733,134 		JBrowse link
G H1f2 H1.2 linker histone, cluster member increases expression ISO Isoproterenol results in increased expression of H1F2 mRNA CTD PMID:20003209 NCBI chr17:41,391,106...41,392,597
Ensembl chr17:41,388,477...41,392,635 		JBrowse link
G H1f4 H1.4 linker histone, cluster member increases expression ISO Isoproterenol results in increased expression of H1F4 mRNA CTD PMID:20003209 NCBI chr17:41,486,574...41,487,355
Ensembl chr17:41,486,560...41,487,403 		JBrowse link
G H2ax H2A.X variant histone increases expression ISO Isoproterenol results in increased expression of H2AX mRNA CTD PMID:21335049 NCBI chr 8:44,671,907...44,673,262
Ensembl chr 8:44,671,786...44,673,239
Ensembl chr 4:44,671,786...44,673,239 		JBrowse link
G Hadha hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha multiple interactions EXP [Isoproterenol co-treated with POSTN protein] results in decreased expression of HADHA mRNA CTD PMID:30303030 NCBI chr 6:26,187,969...26,227,605
Ensembl chr 6:26,187,956...26,227,869 		JBrowse link
G Haghl hydroxyacylglutathione hydrolase-like decreases expression ISO Isoproterenol results in decreased expression of HAGHL mRNA CTD PMID:20003209 NCBI chr10:14,804,957...14,809,495
Ensembl chr10:14,804,997...14,807,665 		JBrowse link
G Hamp hepcidin antimicrobial peptide increases expression EXP
ISO		 Isoproterenol results in increased expression of HAMP mRNA CTD PMID:20211217 PMID:21335049 NCBI chr 1:86,170,926...86,172,865
Ensembl chr 1:86,170,901...86,172,891 		JBrowse link
G Hap1 huntingtin-associated protein 1 increases expression ISO Isoproterenol results in increased expression of HAP1 mRNA CTD PMID:21335049 NCBI chr10:85,277,890...85,286,126
Ensembl chr10:85,277,890...85,286,126 		JBrowse link
G Harbi1 harbinger transposase derived 1 increases expression ISO Isoproterenol results in increased expression of HARBI1 mRNA CTD PMID:20003209 NCBI chr 3:77,681,431...77,689,749
Ensembl chr 3:77,681,431...77,689,724 		JBrowse link
G Hdac2 histone deacetylase 2 increases phosphorylation
multiple interactions		 ISO
EXP		 Isoproterenol results in increased phosphorylation of HDAC2 protein
plantamajoside inhibits the reaction [Isoproterenol results in increased phosphorylation of HDAC2 protein]; Valsartan inhibits the reaction [Isoproterenol results in increased phosphorylation of HDAC2 protein]		 CTD PMID:31009642 NCBI chr20:40,548,244...40,571,609
Ensembl chr20:40,548,250...40,571,609 		JBrowse link
G Heatr5b HEAT repeat containing 5B increases expression ISO Isoproterenol results in increased expression of HEATR5B mRNA CTD PMID:20003209 NCBI chr 6:16,243,424...16,323,444
Ensembl chr 6:16,243,461...16,323,435 		JBrowse link
G Heca hdc homolog, cell cycle regulator increases expression ISO Isoproterenol results in increased expression of HECA mRNA CTD PMID:20003209 NCBI chr 1:12,525,445...12,575,358
Ensembl chr 1:12,525,135...12,576,427 		JBrowse link
G Heph hephaestin increases expression ISO Isoproterenol results in increased expression of HEPH mRNA CTD PMID:20003209 NCBI chr  X:61,151,131...61,402,980
Ensembl chr  X:61,296,345...61,402,980 		JBrowse link
G Herpud1 homocysteine inducible ER protein with ubiquitin like domain 1 increases expression ISO Isoproterenol results in increased expression of HERPUD1 mRNA CTD PMID:20003209 NCBI chr19:10,598,411...10,609,002
Ensembl chr19:10,598,417...10,618,424 		JBrowse link
G Herpud2 HERPUD family member 2 increases expression ISO Isoproterenol results in increased expression of HERPUD2 mRNA CTD PMID:20003209 NCBI chr 8:23,573,374...23,618,380
Ensembl chr 8:23,573,379...23,617,874 		JBrowse link
G Hes1 hes family bHLH transcription factor 1 decreases expression ISO Isoproterenol results in decreased expression of HES1 mRNA CTD PMID:20003209 NCBI chr11:70,705,763...70,708,176
Ensembl chr11:70,705,764...70,708,192 		JBrowse link
G Hexa hexosaminidase subunit alpha increases expression ISO Isoproterenol results in increased expression of HEXA mRNA CTD PMID:20003209 NCBI chr 8:59,936,526...59,961,654
Ensembl chr 8:59,936,660...59,962,013 		JBrowse link
G Hfe homeostatic iron regulator increases expression ISO Isoproterenol results in increased expression of HFE mRNA CTD PMID:20003209 NCBI chr17:41,413,451...41,421,502
Ensembl chr17:41,413,451...41,421,502 		JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha decreases expression ISO Isoproterenol results in decreased expression of HIF1A mRNA CTD PMID:20003209 NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261 		JBrowse link
G Hif1an hypoxia inducible factor 1 subunit alpha inhibitor decreases expression ISO Isoproterenol results in decreased expression of HIF1AN mRNA CTD PMID:24286936 NCBI chr 1:243,419,175...243,440,464
Ensembl chr 1:243,419,194...243,434,327 		JBrowse link
G Hif3a hypoxia inducible factor 3 subunit alpha increases expression ISO
EXP		 Isoproterenol results in increased expression of HIF3A mRNA CTD PMID:24286936 NCBI chr 1:77,718,110...77,750,448
Ensembl chr 1:77,722,471...77,749,758 		JBrowse link
G Hipk1 homeodomain interacting protein kinase 1 increases expression ISO Isoproterenol results in increased expression of HIPK1 mRNA CTD PMID:20003209 NCBI chr 2:191,248,817...191,299,787
Ensembl chr 2:191,248,817...191,298,902 		JBrowse link
G Hipk2 homeodomain interacting protein kinase 2 decreases expression ISO Isoproterenol results in decreased expression of HIPK2 mRNA CTD PMID:20003209 NCBI chr 4:67,439,327...67,619,223
Ensembl chr 4:67,440,501...67,619,223 		JBrowse link
G Hipk3 homeodomain interacting protein kinase 3 increases expression ISO Isoproterenol results in increased expression of HIPK3 mRNA CTD PMID:20003209 NCBI chr 3:90,796,980...90,866,701
Ensembl chr 3:90,800,296...90,867,759 		JBrowse link
G Hk2 hexokinase 2 decreases expression ISO Isoproterenol results in decreased expression of HK2 mRNA CTD PMID:20003209 NCBI chr 4:115,234,509...115,283,530
Ensembl chr 4:115,234,509...115,283,530 		JBrowse link
G Hlf HLF transcription factor, PAR bZIP family member decreases expression ISO Isoproterenol results in decreased expression of HLF mRNA CTD PMID:20003209 NCBI chr10:75,154,244...75,211,884
Ensembl chr10:75,154,507...75,211,935 		JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase multiple interactions
increases activity		 EXP 7-hydroxycoumarin inhibits the reaction [Isoproterenol results in increased activity of HMGCR protein]; [Quercetin co-treated with alpha-Tocopherol] inhibits the reaction [Isoproterenol results in increased activity of HMGCR protein]; alliin inhibits the reaction [Isoproterenol results in increased activity of HMGCR protein]; naringin inhibits the reaction [Isoproterenol results in increased activity of HMGCR protein] CTD PMID:16640830 PMID:16906524 PMID:19595682 PMID:26995004 NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703 		JBrowse link
G Hmgcs1 3-hydroxy-3-methylglutaryl-CoA synthase 1 increases expression ISO Isoproterenol results in increased expression of HMGCS1 mRNA CTD PMID:21335049 NCBI chr 2:51,649,368...51,667,100
Ensembl chr 2:51,649,497...51,667,100 		JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions
decreases expression
increases expression		 ISO
EXP		 N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Isoproterenol results in increased expression of HMOX1 protein]; Propranolol inhibits the reaction [Isoproterenol results in increased expression of HMOX1 protein]
Isoproterenol results in decreased expression of HMOX1 mRNA; Isoproterenol results in decreased expression of HMOX1 protein
Isoproterenol results in increased expression of HMOX1 mRNA; Isoproterenol results in increased expression of HMOX1 protein
[erdosteine co-treated with Isoproterenol] results in increased expression of HMOX1 protein; anethole promotes the reaction [Isoproterenol results in increased expression of HMOX1 mRNA]; anethole promotes the reaction [Isoproterenol results in increased expression of HMOX1 protein]; Doxorubicin inhibits the reaction [Isoproterenol results in increased expression of HMOX1 mRNA]; protocatechuic acid inhibits the reaction [Isoproterenol results in decreased expression of HMOX1 mRNA]; punicalagin inhibits the reaction [Isoproterenol results in decreased expression of HMOX1 protein]		 CTD PMID:15179140 PMID:19483313 PMID:20003209 PMID:21823215 PMID:22908232 More... NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Hnrnph3 heterogeneous nuclear ribonucleoprotein H3 decreases expression ISO Isoproterenol results in decreased expression of HNRNPH3 mRNA CTD PMID:20003209 NCBI chr20:25,616,400...25,625,814
Ensembl chr20:25,614,733...25,625,750 		JBrowse link
G Hnrnpr heterogeneous nuclear ribonucleoprotein R decreases expression ISO Isoproterenol results in decreased expression of HNRNPR mRNA CTD PMID:20003209 NCBI chr 5:148,542,999...148,574,888
Ensembl chr 5:148,543,044...148,574,867 		JBrowse link
G Homer1 homer scaffold protein 1 increases expression EXP Isoproterenol results in increased expression of HOMER1 mRNA alternative form CTD PMID:16786172 NCBI chr 2:24,542,777...24,645,715
Ensembl chr 2:24,543,093...24,644,785 		JBrowse link
G Hopx HOP homeobox decreases expression ISO Isoproterenol results in decreased expression of HOPX mRNA CTD PMID:20003209 NCBI chr14:31,055,912...31,082,909
Ensembl chr14:31,075,148...31,082,909 		JBrowse link
G Hpca hippocalcin affects localization EXP Isoproterenol affects the localization of HPCA protein CTD PMID:21078978 NCBI chr 5:141,455,616...141,466,252
Ensembl chr 5:141,455,613...141,463,841 		JBrowse link
G Hpse heparanase increases expression EXP Isoproterenol results in increased expression of HPSE protein CTD PMID:16327176 NCBI chr14:8,896,593...8,937,011
Ensembl chr14:8,896,593...8,937,010 		JBrowse link
G Hras HRas proto-oncogene, GTPase increases activity EXP Isoproterenol results in increased activity of HRAS protein CTD PMID:8484791 NCBI chr 1:196,290,127...196,299,823
Ensembl chr 1:196,296,263...196,300,615 		JBrowse link
G Hs2st1 heparan sulfate 2-O-sulfotransferase 1 decreases expression ISO Isoproterenol results in decreased expression of HS2ST1 mRNA CTD PMID:20003209 NCBI chr 2:233,508,018...233,641,769
Ensembl chr 2:233,508,021...233,641,769 		JBrowse link
G Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 decreases expression ISO Isoproterenol results in decreased expression of HSD3B1 mRNA CTD PMID:21335049 NCBI chr 2:186,169,864...186,175,984
Ensembl chr 2:186,169,863...186,175,999 		JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 increases expression ISO Isoproterenol results in increased expression of HSP90AA1 mRNA CTD PMID:21335049 NCBI chr 6:129,702,376...129,707,907
Ensembl chr 6:129,702,383...129,707,268 		JBrowse link
G Hsp90b1 heat shock protein 90 beta family member 1 decreases expression ISO Isoproterenol results in decreased expression of HSP90B1 mRNA CTD PMID:20003209 NCBI chr 7:21,110,431...21,124,762
Ensembl chr 7:21,110,457...21,124,788 		JBrowse link
G Hspa1l heat shock protein family A (Hsp70) member 1 like increases expression
decreases expression		 ISO
EXP		 Isoproterenol results in increased expression of HSPA1L mRNA
Isoproterenol results in decreased expression of HSPA1L mRNA		 CTD PMID:20003209 PMID:24286936 NCBI chr20:3,848,843...3,855,571
Ensembl chr20:3,848,843...3,855,571 		JBrowse link
G Hspa2 heat shock protein family A (Hsp70) member 2 increases expression EXP
ISO		 Isoproterenol results in increased expression of HSPA2 mRNA CTD PMID:20211217 PMID:24286936 NCBI chr 6:95,128,504...95,131,281
Ensembl chr 6:95,128,350...95,131,287 		JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 increases expression
multiple interactions
decreases expression		 ISO
EXP		 Isoproterenol results in increased expression of HSPA5 mRNA
[Acrolein results in increased susceptibility to Isoproterenol] which results in increased expression of HSPA5 protein; Acrolein promotes the reaction [Isoproterenol results in increased expression of HSPA5 mRNA]; Plant Extracts inhibits the reaction [[Acrolein results in increased susceptibility to Isoproterenol] which results in increased expression of HSPA5 protein]; Plant Extracts inhibits the reaction [Acrolein promotes the reaction [Isoproterenol results in increased expression of HSPA5 mRNA]]
Isoproterenol results in decreased expression of HSPA5 mRNA		 CTD PMID:21335049 PMID:24286936 PMID:29414845 NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891 		JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 decreases expression ISO Isoproterenol results in decreased expression of HSPA8 mRNA CTD PMID:20003209 PMID:24286936 NCBI chr 8:41,183,397...41,187,260
Ensembl chr 8:41,183,264...41,187,259 		JBrowse link
G Hspb1 heat shock protein family B (small) member 1 multiple interactions
increases expression		 EXP Curcumin promotes the reaction [Isoproterenol results in increased expression of HSPB1 protein]
Isoproterenol results in increased expression of HSP27 protein; Isoproterenol results in increased expression of HSPB1 protein		 CTD PMID:10559386 PMID:20125031 NCBI chr12:20,794,014...20,795,675
Ensembl chr12:20,794,028...20,795,743 		JBrowse link
G Hspb7 heat shock protein family B (small) member 7 increases expression EXP Isoproterenol results in increased expression of HSPB7 mRNA CTD PMID:24286936 NCBI chr 5:153,727,782...153,731,268
Ensembl chr 5:153,727,588...153,731,266 		JBrowse link
G Hspg2 heparan sulfate proteoglycan 2 decreases expression ISO Isoproterenol results in decreased expression of HSPG2 mRNA CTD PMID:20003209 NCBI chr 5:149,677,437...149,778,594
Ensembl chr 5:149,677,476...149,778,594 		JBrowse link
G Hsph1 heat shock protein family H (Hsp110) member 1 increases expression ISO Isoproterenol results in increased expression of HSPH1 mRNA CTD PMID:21335049 NCBI chr12:5,390,916...5,410,224
Ensembl chr12:5,390,922...5,410,224 		JBrowse link
G Htra2 HtrA serine peptidase 2 decreases expression ISO Isoproterenol results in decreased expression of HTRA2 mRNA CTD PMID:21335049 NCBI chr 4:115,556,914...115,560,202
Ensembl chr 4:115,556,916...115,560,095 		JBrowse link
G Htra3 HtrA serine peptidase 3 increases expression ISO Isoproterenol results in increased expression of HTRA3 mRNA CTD PMID:20003209 NCBI chr14:75,068,917...75,097,315
Ensembl chr14:75,068,917...75,097,315 		JBrowse link
G Hyou1 hypoxia up-regulated 1 decreases expression ISO Isoproterenol results in decreased expression of HYOU1 mRNA CTD PMID:20003209 NCBI chr 8:44,706,073...44,718,189
Ensembl chr 8:44,706,263...44,718,186 		JBrowse link
G Icam1 intercellular adhesion molecule 1 increases expression ISO Isoproterenol results in increased expression of ICAM1 mRNA CTD PMID:20003209 PMID:21335049 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438 		JBrowse link
G Id1 inhibitor of DNA binding 1 decreases expression
increases expression 		ISO
EXP		 Isoproterenol results in decreased expression of ID1 mRNA
isoprenaline increases expression of mRNA in neonatal rat cardiomyocytes		 CTD
RGD		 PMID:21335049 PMID:26873969 RGD:11526363 NCBI chr 3:141,210,666...141,212,420
Ensembl chr 3:141,211,267...141,212,419 		JBrowse link
G Ier3 immediate early response 3 multiple interactions
affects response to substance		 ISO IER3 protein affects the reaction [Isoproterenol results in increased abundance of Cyclic AMP]; Pertussis Toxin affects the reaction [IER3 protein affects the reaction [Isoproterenol results in increased abundance of Cyclic AMP]]; Pertussis Toxin affects the reaction [IER3 protein affects the susceptibility to Isoproterenol] CTD PMID:20713914 NCBI chr20:2,928,378...2,929,582
Ensembl chr20:2,928,378...2,929,583 		JBrowse link
G Ifna1 interferon, alpha 1 decreases expression EXP Isoproterenol results in decreased expression of IFNA1 mRNA CTD PMID:24286936 NCBI chr 5:103,097,356...103,097,925
Ensembl chr 5:103,097,356...103,097,925 		JBrowse link
G Ifng interferon gamma decreases secretion ISO Isoproterenol results in decreased secretion of IFNG protein CTD PMID:15342205 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375 		JBrowse link
G Ifngr2 interferon gamma receptor 2 decreases expression ISO Isoproterenol results in decreased expression of IFNGR2 mRNA CTD PMID:20003209 NCBI chr11:30,779,733...30,798,005
Ensembl chr11:30,779,733...30,798,005 		JBrowse link
G Ifrd1 interferon-related developmental regulator 1 increases expression ISO Isoproterenol results in increased expression of IFRD1 mRNA CTD PMID:20003209 NCBI chr 6:57,269,395...57,317,833
Ensembl chr 6:57,269,384...57,288,990 		JBrowse link
G Ift74 intraflagellar transport 74 increases expression ISO Isoproterenol results in increased expression of IFT74 mRNA CTD PMID:20003209 NCBI chr 5:109,460,372...109,563,839
Ensembl chr 5:109,474,255...109,563,833 		JBrowse link
G Igf1 insulin-like growth factor 1 decreases expression
increases expression
multiple interactions		 ISO
EXP		 Isoproterenol results in decreased expression of IGF1 mRNA
Isoproterenol results in increased expression of IGF1 mRNA; Isoproterenol results in increased expression of IGF1 protein
candesartan cilexetil inhibits the reaction [Isoproterenol results in increased expression of IGF1 mRNA]; candesartan cilexetil inhibits the reaction [Isoproterenol results in increased expression of IGF1 protein]		 CTD PMID:10547078 PMID:20003209 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296 		JBrowse link
G Igf1r insulin-like growth factor 1 receptor increases expression ISO Isoproterenol results in increased expression of IGF1R mRNA CTD PMID:20003209 NCBI chr 1:121,549,831...121,838,548
Ensembl chr 1:121,550,743...121,831,777 		JBrowse link
G Igf2bp2 insulin-like growth factor 2 mRNA binding protein 2 increases expression ISO Isoproterenol results in increased expression of IGF2BP2 mRNA CTD PMID:20003209 NCBI chr11:78,874,402...78,974,392
Ensembl chr11:78,874,414...78,974,377 		JBrowse link
G Igfbp3 insulin-like growth factor binding protein 3 decreases expression
multiple interactions		 EXP Isoproterenol results in decreased expression of IGFBP3
SI 27 inhibits the reaction [Isoproterenol results in decreased expression of IGFBP3]		 CTD PMID:12883319 NCBI chr14:82,056,347...82,064,083
Ensembl chr14:82,056,347...82,064,083 		JBrowse link
G Il10 interleukin 10 multiple interactions
decreases expression		 ISO
EXP		 Isoproterenol promotes the reaction [Lipopolysaccharides results in increased expression of IL10 protein]
Quercetin inhibits the reaction [Isoproterenol results in decreased expression of IL10 protein]		 CTD PMID:9038718 PMID:27527349 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313 		JBrowse link
G Il12a interleukin 12A decreases expression EXP Isoproterenol results in decreased expression of IL12A protein CTD PMID:24286936 NCBI chr 2:152,965,769...152,973,035
Ensembl chr 2:152,965,769...152,972,734 		JBrowse link
G Il12b interleukin 12B increases expression ISO Isoproterenol results in increased expression of IL12B protein CTD PMID:24286936 NCBI chr10:28,888,832...28,903,802
Ensembl chr10:28,893,008...28,902,903 		JBrowse link
G Il17a interleukin 17A increases expression
multiple interactions		 EXP Isoproterenol results in increased expression of IL17A protein
Glyburide promotes the reaction [Isoproterenol results in increased expression of IL17A protein]; pyrvinium inhibits the reaction [Glyburide promotes the reaction [Isoproterenol results in increased expression of IL17A protein]]; pyrvinium inhibits the reaction [Isoproterenol results in increased expression of IL17A protein]		 CTD PMID:19909738 PMID:35305975 NCBI chr 9:23,144,402...23,147,889
Ensembl chr 9:23,144,402...23,147,889 		JBrowse link
G Il17rd interleukin 17 receptor D increases expression ISO Isoproterenol results in increased expression of IL17RD mRNA CTD PMID:20003209 NCBI chr16:2,228,438...2,295,122
Ensembl chr16:2,228,287...2,292,556 		JBrowse link
G Il18 interleukin 18 multiple interactions
increases expression
decreases expression		 ISO
EXP		 ADRB2 protein affects the reaction [Isoproterenol results in increased expression of IL18 mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Isoproterenol results in increased secretion of IL18 protein]; ICI 118551 inhibits the reaction [Isoproterenol results in increased expression of IL18 mRNA]; ICI 118551 inhibits the reaction [Isoproterenol results in increased expression of IL18 protein]; Isoproterenol results in increased expression of and results in increased secretion of IL18 protein; Isoproterenol results in increased expression of and results in increased stability of IL18 mRNA; Pertussis Toxin inhibits the reaction [Isoproterenol results in increased secretion of IL18 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Isoproterenol results in increased expression of and results in increased secretion of IL18 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Isoproterenol results in increased expression of IL18 mRNA]; wortmannin inhibits the reaction [Isoproterenol results in increased secretion of IL18 protein]
Isoproterenol results in decreased expression of IL18 mRNA		 CTD PMID:15178407 PMID:21335049 PMID:24286936 NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887 		JBrowse link
G Il1a interleukin 1 alpha decreases expression
increases expression		 ISO
EXP		 Isoproterenol results in decreased expression of IL1A mRNA
Isoproterenol results in increased expression of IL1A mRNA		 CTD PMID:24286936 PMID:32816093 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822 		JBrowse link
G Il1b interleukin 1 beta multiple interactions
decreases expression
increases expression		 ISO
EXP		 SB 206553 inhibits the reaction [Isoproterenol results in increased expression of IL1B]; ZD 7155 inhibits the reaction [Isoproterenol results in increased expression of IL1B protein]
Isoproterenol results in decreased expression of IL1B mRNA
Isoproterenol results in decreased expression of IL1B mRNA; Isoproterenol results in decreased expression of IL1B protein
Isoproterenol results in increased expression of IL1B mRNA; Isoproterenol results in increased expression of IL1B protein
Isoproterenol results in increased expression of IL1B; Isoproterenol results in increased expression of IL1B mRNA
Isoproterenol results in increased expression of IL1B; Isoproterenol results in increased expression of IL1B mRNA; Isoproterenol results in increased expression of IL1B protein
5-Methoxypsoralen inhibits the reaction [Isoproterenol results in increased expression of IL1B protein]; anethole inhibits the reaction [Isoproterenol results in increased expression of IL1B protein]; Ellagic Acid inhibits the reaction [Isoproterenol results in increased expression of IL1B mRNA]; Glyburide promotes the reaction [Isoproterenol results in increased expression of IL1B protein]; p-coumaric acid inhibits the reaction [Isoproterenol results in increased expression of IL1B mRNA]; protocatechuic acid inhibits the reaction [Isoproterenol results in increased expression of IL1B protein]; punicalagin inhibits the reaction [Isoproterenol results in increased expression of IL1B protein]; pyrvinium inhibits the reaction [Glyburide promotes the reaction [Isoproterenol results in increased expression of IL1B protein]]; pyrvinium inhibits the reaction [Isoproterenol results in increased expression of IL1B protein]; Sirolimus inhibits the reaction [Isoproterenol results in increased expression of IL1B mRNA]; Sirolimus inhibits the reaction [Isoproterenol results in increased expression of IL1B protein]; TNF protein inhibits the reaction [Sirolimus inhibits the reaction [Isoproterenol results in increased expression of IL1B mRNA]]; TNF protein inhibits the reaction [Sirolimus inhibits the reaction [Isoproterenol results in increased expression of IL1B protein]]; zingiberene inhibits the reaction [Isoproterenol results in increased expression of IL1B mRNA]; zingiberene inhibits the reaction [Isoproterenol results in increased expression of IL1B protein]		 CTD PMID:9387890 PMID:12215284 PMID:15302781 PMID:18487443 PMID:19023134 More... NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il1rn interleukin 1 receptor antagonist affects response to substance ISO IL1RN protein affects the susceptibility to Isoproterenol CTD PMID:10487780 NCBI chr 3:7,111,567...7,127,451
Ensembl chr 3:7,111,550...7,127,445 		JBrowse link
G Il2 interleukin 2 increases expression
multiple interactions		 EXP Isoproterenol results in increased expression of IL2 mRNA; Isoproterenol results in increased expression of IL2 protein
Sirolimus inhibits the reaction [Isoproterenol results in increased expression of IL2 mRNA]; Sirolimus inhibits the reaction [Isoproterenol results in increased expression of IL2 protein]; TNF protein inhibits the reaction [Sirolimus inhibits the reaction [Isoproterenol results in increased expression of IL2 mRNA]]; TNF protein inhibits the reaction [Sirolimus inhibits the reaction [Isoproterenol results in increased expression of IL2 protein]]		 CTD PMID:25045214 NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566 		JBrowse link
G Il24 interleukin 24 increases expression ISO Isoproterenol results in increased expression of IL24 mRNA CTD PMID:32816093 NCBI chr13:42,353,089...42,358,487
Ensembl chr13:42,353,090...42,358,487 		JBrowse link
G Il4 interleukin 4 decreases expression
increases expression		 ISO
EXP		 Isoproterenol results in decreased expression of IL4 mRNA
Isoproterenol results in increased expression of IL4 mRNA
Isoproterenol results in increased expression of IL4 protein		 CTD PMID:24286936 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750 		JBrowse link
G Il4r interleukin 4 receptor increases expression ISO Isoproterenol results in increased expression of IL4RA mRNA CTD PMID:20003209 NCBI chr 1:180,115,061...180,139,981
Ensembl chr 1:180,115,120...180,139,980 		JBrowse link
G Il5ra interleukin 5 receptor subunit alpha affects response to substance ISO IL5RA protein affects the susceptibility to Isoproterenol CTD PMID:10487780 NCBI chr 4:139,630,652...139,664,593
Ensembl chr 4:139,632,066...139,668,544 		JBrowse link
G Il6 interleukin 6 multiple interactions
increases secretion
increases expression
decreases expression
decreases secretion		 ISO
EXP		 ANXA1 affects the reaction [Isoproterenol results in decreased secretion of IL6 protein]; biochanin A inhibits the reaction [Isoproterenol results in increased expression of IL6 mRNA]; Genistein promotes the reaction [Isoproterenol results in increased secretion of IL6 protein]; Isoproterenol promotes the reaction [Lipopolysaccharides results in increased expression of IL6 protein]; oxophenylarsine inhibits the reaction [Isoproterenol results in increased secretion of IL6 protein]; SB 206553 inhibits the reaction [Isoproterenol results in increased expression of IL6]; ZD 7155 inhibits the reaction [Isoproterenol results in increased expression of IL6 protein]
Isoproterenol results in increased expression of IL6 mRNA; Isoproterenol results in increased expression of IL6 protein
Isoproterenol results in decreased expression of IL6 mRNA
5-Methoxypsoralen inhibits the reaction [Isoproterenol results in increased expression of IL6 protein]; anethole inhibits the reaction [Isoproterenol results in increased expression of IL6 protein]; Apigenin inhibits the reaction [Isoproterenol results in increased expression of IL6 protein]; Ellagic Acid inhibits the reaction [Isoproterenol results in increased expression of IL6 mRNA]; Enalapril inhibits the reaction [Isoproterenol results in increased expression of IL6 protein]; erdosteine inhibits the reaction [Isoproterenol results in increased expression of IL6 protein]; ferruginol inhibits the reaction [Isoproterenol results in increased secretion of IL6 protein]; geraniol inhibits the reaction [Isoproterenol results in increased expression of IL6 protein]; Hesperidin inhibits the reaction [Isoproterenol results in increased expression of IL6 protein]; ICI 118551 inhibits the reaction [Isoproterenol inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]]; ICI 118551 inhibits the reaction [Isoproterenol inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 protein]]; Isoproterenol inhibits the reaction [Isoproterenol results in increased expression of IL6 protein]; Isoproterenol inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]; Isoproterenol inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 protein]; Isoproterenol results in increased expression of and results in increased secretion of IL6 protein; Metformin inhibits the reaction [Isoproterenol results in increased expression of and results in increased secretion of IL6 protein]; Metformin inhibits the reaction [Isoproterenol results in increased expression of IL6 mRNA]; p-coumaric acid inhibits the reaction [Isoproterenol results in increased expression of IL6 mRNA]; punicalagin inhibits the reaction [Isoproterenol results in increased expression of IL6 protein]; Quercetin inhibits the reaction [Isoproterenol results in increased expression of IL6 protein]; xanthone inhibits the reaction [Isoproterenol results in increased expression of IL6 protein]; zingiberene inhibits the reaction [Isoproterenol results in increased expression of IL6 mRNA]; zingiberene inhibits the reaction [Isoproterenol results in increased expression of IL6 protein]
Isoproterenol results in increased expression of IL6; Isoproterenol results in increased expression of IL6 mRNA; Isoproterenol results in increased expression of IL6 protein
Isoproterenol promotes the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]		 CTD PMID:9038718 PMID:9688336 PMID:10525314 PMID:11406463 PMID:15302781 More... NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Il7 interleukin 7 increases expression ISO
EXP		 Isoproterenol results in increased expression of IL7 protein CTD PMID:24286936 NCBI chr 2:94,235,219...94,280,075
Ensembl chr 2:94,234,766...94,280,075 		JBrowse link
G Immt inner membrane mitochondrial protein decreases expression ISO Isoproterenol results in decreased expression of IMMT mRNA CTD PMID:20003209 NCBI chr 4:103,880,482...103,919,116
Ensembl chr 4:103,880,459...103,919,109 		JBrowse link
G Inhbb inhibin subunit beta B increases expression ISO Isoproterenol results in increased expression of INHBB mRNA CTD PMID:20003209 NCBI chr13:30,530,860...30,536,566
Ensembl chr13:30,530,860...30,537,832 		JBrowse link
G Ins2 insulin 2 multiple interactions
increases expression
affects expression		 EXP INS protein inhibits the reaction [Isoproterenol results in increased phosphorylation of PRKAA1 protein]; OPC 3911 inhibits the reaction [INS protein inhibits the reaction [Isoproterenol results in increased phosphorylation of PRKAA1 protein]]
Isoproterenol results in increased expression of INS protein
Isoproterenol affects the expression of INS protein		 CTD PMID:1129332 PMID:1170870 PMID:19167487 NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775 		JBrowse link
G Ints3 integrator complex subunit 3 increases expression ISO Isoproterenol results in increased expression of INTS3 mRNA CTD PMID:20003209 NCBI chr 2:175,859,421...175,911,683
Ensembl chr 2:175,859,440...175,911,709 		JBrowse link
G Ipo13 importin 13 decreases expression ISO Isoproterenol results in decreased expression of IPO13 mRNA CTD PMID:20003209 NCBI chr 5:131,433,770...131,454,044
Ensembl chr 5:131,433,776...131,454,043 		JBrowse link
G Irak3 interleukin-1 receptor-associated kinase 3 increases expression ISO Isoproterenol results in increased expression of IRAK3 mRNA CTD PMID:20003209 NCBI chr 7:55,653,949...55,714,371
Ensembl chr 7:55,653,962...55,713,121 		JBrowse link
G Irs1 insulin receptor substrate 1 increases expression ISO Isoproterenol results in increased expression of IRS1 mRNA CTD PMID:20003209 NCBI chr 9:83,552,964...83,605,797
Ensembl chr 9:83,548,944...83,606,122 		JBrowse link
G Irx4 iroquois homeobox 4 decreases expression ISO Isoproterenol results in decreased expression of IRX4 mRNA CTD PMID:20003209 NCBI chr 1:30,030,561...30,039,549
Ensembl chr 1:30,030,561...30,039,549 		JBrowse link
G Itgam integrin subunit alpha M multiple interactions ISO Isoproterenol promotes the reaction [Theophylline inhibits the reaction [Platelet Activating Factor results in increased expression of ITGAM protein]] CTD PMID:9762784 NCBI chr 1:182,659,047...182,709,501
Ensembl chr 1:182,659,000...182,709,503 		JBrowse link
G Itgb1 integrin subunit beta 1 multiple interactions
decreases expression		 ISO
EXP		 DMD gene mutant form promotes the reaction [ITGB1 gene affects the susceptibility to Isoproterenol]
Isoproterenol results in decreased expression of ITGB1		 CTD PMID:18340010 PMID:18808529 NCBI chr19:56,705,123...56,753,199
Ensembl chr19:56,705,171...56,753,195 		JBrowse link
G Itgbl1 integrin subunit beta like 1 increases expression ISO Isoproterenol results in increased expression of ITGBL1 mRNA CTD PMID:20003209 NCBI chr15:100,780,184...101,041,734
Ensembl chr15:100,780,184...101,041,733 		JBrowse link
G Itih3 inter-alpha trypsin inhibitor, heavy chain 3 increases expression ISO Isoproterenol results in increased expression of ITIH3 mRNA CTD PMID:20003209 NCBI chr16:6,101,922...6,117,154
Ensembl chr16:6,101,930...6,116,924 		JBrowse link
G Itih4 inter-alpha-trypsin inhibitor heavy chain 4 increases expression ISO Isoproterenol results in increased expression of ITIH4 mRNA CTD PMID:20003209 NCBI chr16:6,080,539...6,095,710
Ensembl chr16:6,080,539...6,095,708 		JBrowse link
G Itk IL2-inducible T-cell kinase decreases expression ISO Isoproterenol results in decreased expression of ITK mRNA CTD PMID:20003209 NCBI chr10:30,753,344...30,814,685
Ensembl chr10:30,753,344...30,814,685 		JBrowse link
G Itpkb inositol-trisphosphate 3-kinase B decreases expression ISO Isoproterenol results in decreased expression of ITPKB mRNA CTD PMID:20003209 NCBI chr13:92,069,160...92,164,281
Ensembl chr13:92,069,216...92,162,004 		JBrowse link
G Jade2 jade family PHD finger 2 increases expression ISO Isoproterenol results in increased expression of JADE2 mRNA CTD PMID:20003209 NCBI chr10:36,075,239...36,124,210
Ensembl chr10:36,078,917...36,116,984 		JBrowse link
G Jarid2 jumonji and AT-rich interaction domain containing 2 decreases expression ISO Isoproterenol results in decreased expression of JARID2 mRNA CTD PMID:20003209 NCBI chr17:19,777,487...19,957,696
Ensembl chr17:19,777,266...19,955,690 		JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions
decreases expression
increases expression		 ISO
EXP		 [N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide co-treated with U 0126] inhibits the reaction [Isoproterenol results in increased expression of JUN mRNA]; [Phenylephrine co-treated with Isoproterenol] results in increased expression of JUN mRNA; EGR1 protein affects the reaction [[Phenylephrine co-treated with Isoproterenol] results in increased expression of JUN mRNA]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Isoproterenol results in increased expression of JUN mRNA]
Isoproterenol results in decreased expression of JUN mRNA
Isoproterenol results in increased expression of JUN mRNA; Isoproterenol results in increased expression of JUN protein
[Isoproterenol co-treated with POSTN protein] results in decreased expression of JUN mRNA; Isoproterenol promotes the reaction [JUN protein binds to FOS protein]		 CTD PMID:10710348 PMID:14764439 PMID:21177286 PMID:30303030 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656 		JBrowse link
G Junb JunB proto-oncogene, AP-1 transcription factor subunit increases expression
multiple interactions		 EXP
ISO		 Isoproterenol results in increased expression of JUNB
[N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide co-treated with U 0126] inhibits the reaction [Isoproterenol results in increased expression of JUNB mRNA]; JUNB protein promotes the reaction [Isoproterenol results in decreased expression of COL2A1 mRNA]; JUNB protein promotes the reaction [Isoproterenol results in decreased expression of SOX6 mRNA]; JUNB protein promotes the reaction [Isoproterenol results in decreased expression of SOX6 protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Isoproterenol results in increased expression of JUNB mRNA]; U 0126 inhibits the reaction [Isoproterenol results in increased expression of JUNB mRNA]
Isoproterenol results in increased expression of JUNB mRNA; Isoproterenol results in increased expression of JUNB protein		 CTD PMID:7905536 PMID:21177286 NCBI chr19:23,176,265...23,178,049
Ensembl chr19:23,176,294...23,178,035 		JBrowse link
G Kank3 KN motif and ankyrin repeat domains 3 increases expression ISO Isoproterenol results in increased expression of KANK3 mRNA CTD PMID:20003209 NCBI chr 7:14,594,358...14,607,675
Ensembl chr 7:14,594,422...14,607,675 		JBrowse link
G Kcna5 potassium voltage-gated channel subfamily A member 5 increases expression ISO Isoproterenol results in increased expression of KCNA5 mRNA CTD PMID:20003209 NCBI chr 4:159,354,689...159,358,173
Ensembl chr 4:159,350,097...159,357,697 		JBrowse link
G Kcnb1 potassium voltage-gated channel subfamily B member 1 decreases expression ISO Isoproterenol results in decreased expression of KCNB1 mRNA CTD PMID:20003209 NCBI chr 3:155,820,255...155,913,383
Ensembl chr 3:155,822,963...155,916,194 		JBrowse link
G Kcnd2 potassium voltage-gated channel subfamily D member 2 decreases expression ISO Isoproterenol results in decreased expression of KCND2 mRNA CTD PMID:20003209 NCBI chr 4:49,775,812...50,277,746
Ensembl chr 4:49,776,246...50,277,728 		JBrowse link
G Kcne1 potassium voltage-gated channel subfamily E regulatory subunit 1 multiple interactions
decreases expression		 ISO Isoproterenol results in increased activity of [KCNQ1 protein binds to KCNE1 protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Isoproterenol results in increased activity of [KCNQ1 protein binds to KCNE1 protein]]
Isoproterenol results in decreased expression of KCNE1 mRNA		 CTD PMID:16909339 PMID:20003209 NCBI chr11:31,580,951...31,594,116
Ensembl chr11:31,580,742...31,593,901 		JBrowse link
G Kcnh6 potassium voltage-gated channel subfamily H member 6 increases expression ISO Isoproterenol results in increased expression of KCNH6 mRNA CTD PMID:20003209 NCBI chr10:90,949,240...90,970,746
Ensembl chr10:90,949,846...90,970,701 		JBrowse link
G Kcnq1 potassium voltage-gated channel subfamily Q member 1 multiple interactions ISO
EXP		 Isoproterenol results in increased activity of [KCNQ1 protein binds to KCNE1 protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Isoproterenol results in increased activity of [KCNQ1 protein binds to KCNE1 protein]]
[Isoproterenol co-treated with POSTN protein] results in decreased expression of KCNQ1 mRNA		 CTD PMID:16909339 PMID:30303030 NCBI chr 1:198,291,711...198,624,683
Ensembl chr 1:198,291,766...198,624,669 		JBrowse link
G Kcnt2 potassium sodium-activated channel subfamily T member 2 increases expression ISO Isoproterenol results in increased expression of KCNT2 mRNA CTD PMID:20003209 NCBI chr13:51,664,129...52,059,209
Ensembl chr13:51,664,686...52,056,987 		JBrowse link
G Kdm6b lysine demethylase 6B decreases expression ISO Isoproterenol results in decreased expression of KDM6B mRNA CTD PMID:20003209 NCBI chr10:54,120,716...54,142,212
Ensembl chr10:54,121,848...54,130,794 		JBrowse link
G Kdr kinase insert domain receptor decreases expression ISO Isoproterenol results in decreased expression of KDR mRNA CTD PMID:20003209 NCBI chr14:32,217,871...32,261,018
Ensembl chr14:32,217,871...32,261,018 		JBrowse link
G Keap1 Kelch-like ECH-associated protein 1 decreases expression
increases expression
multiple interactions		 EXP Isoproterenol results in decreased expression of KEAP1 mRNA
Isoproterenol results in increased expression of KEAP1 mRNA; Isoproterenol results in increased expression of KEAP1 protein
[Isoproterenol co-treated with POSTN protein] results in decreased expression of KEAP1 mRNA; anethole inhibits the reaction [Isoproterenol results in increased expression of KEAP1 mRNA]; anethole inhibits the reaction [Isoproterenol results in increased expression of KEAP1 protein]		 CTD PMID:30303030 PMID:35430261 NCBI chr 8:19,768,375...19,777,862
Ensembl chr 8:19,768,375...19,777,862 		JBrowse link
G Kif1b kinesin family member 1B decreases expression ISO Isoproterenol results in decreased expression of KIF1B mRNA CTD PMID:20003209 NCBI chr 5:159,607,697...159,742,778
Ensembl chr 5:159,561,271...159,742,778 		JBrowse link
G Klf15 KLF transcription factor 15 increases expression ISO Isoproterenol results in increased expression of KLF15 mRNA CTD PMID:20003209 NCBI chr 4:122,965,718...122,978,403
Ensembl chr 4:122,965,807...122,978,374 		JBrowse link
G Klf3 KLF transcription factor 3 increases expression ISO Isoproterenol results in increased expression of KLF3 mRNA CTD PMID:20003209 NCBI chr14:43,474,767...43,505,801
Ensembl chr14:43,474,767...43,497,209 		JBrowse link
G Klhdc8a kelch domain containing 8A decreases expression ISO Isoproterenol results in decreased expression of KLHDC8A mRNA CTD PMID:20003209 NCBI chr13:43,735,702...43,744,277
Ensembl chr13:43,736,192...43,744,277 		JBrowse link
G Klhl2 kelch-like family member 2 increases expression ISO Isoproterenol results in increased expression of KLHL2 mRNA CTD PMID:20003209 NCBI chr16:24,860,744...24,973,348
Ensembl chr16:24,860,667...24,973,341 		JBrowse link
G Klhl24 kelch-like family member 24 increases expression ISO Isoproterenol results in increased expression of KLHL24 mRNA CTD PMID:20003209 NCBI chr11:80,843,621...80,877,649
Ensembl chr11:80,846,755...80,877,636 		JBrowse link
G Klhl40 kelch-like family member 40 increases expression EXP Isoproterenol results in increased expression of KLHL40 mRNA CTD PMID:20211217 NCBI chr 8:121,441,285...121,446,801
Ensembl chr 8:121,441,287...121,446,800 		JBrowse link
G Klhl41 kelch-like family member 41 increases expression EXP Isoproterenol results in increased expression of KLHL41 mRNA CTD PMID:20211217 NCBI chr 3:54,434,291...54,447,415
Ensembl chr 3:54,434,234...54,449,222 		JBrowse link
G Klhl7 kelch-like family member 7 increases expression ISO Isoproterenol results in increased expression of KLHL7 mRNA CTD PMID:20003209 NCBI chr 4:11,006,366...11,055,399
Ensembl chr 4:11,006,375...11,055,541 		JBrowse link
G Kmt5a lysine methyltransferase 5A decreases expression ISO Isoproterenol results in decreased expression of KMT5A mRNA CTD PMID:20003209 NCBI chr12:32,139,353...32,167,777
Ensembl chr12:32,139,178...32,162,711 		JBrowse link
G Kpna3 karyopherin subunit alpha 3 multiple interactions EXP [Isoproterenol co-treated with POSTN protein] results in decreased expression of KPNA3 mRNA CTD PMID:30303030 NCBI chr15:35,536,310...35,610,066
Ensembl chr15:35,536,316...35,610,419 		JBrowse link
G Kpna6 karyopherin subunit alpha 6 multiple interactions EXP [Isoproterenol co-treated with POSTN protein] results in decreased expression of KPNA6 mRNA CTD PMID:30303030 NCBI chr 5:141,988,111...142,021,483
Ensembl chr 5:141,991,568...142,021,120 		JBrowse link
G Kras KRAS proto-oncogene, GTPase increases expression ISO Isoproterenol results in increased expression of KRAS mRNA CTD PMID:21335049 NCBI chr 4:178,185,418...178,218,484 JBrowse link
G Krt18 keratin 18 increases expression ISO Isoproterenol results in increased expression of KRT18 mRNA CTD PMID:21335049 NCBI chr 7:133,157,486...133,161,162
Ensembl chr 7:133,157,475...133,161,166
Ensembl chr10:133,157,475...133,161,166 		JBrowse link
G Krt222 keratin 222 decreases expression ISO Isoproterenol results in decreased expression of KRT222 mRNA CTD PMID:20003209 NCBI chr10:84,184,137...84,196,122
Ensembl chr10:84,186,173...84,196,015 		JBrowse link
G Ky kyphoscoliosis peptidase decreases expression ISO Isoproterenol results in decreased expression of KY mRNA CTD PMID:20003209 NCBI chr 8:103,086,959...103,126,305
Ensembl chr 8:103,086,630...103,126,024 		JBrowse link
G Lama2 laminin subunit alpha 2 decreases expression EXP Isoproterenol results in decreased expression of LAMA2 CTD PMID:18808529 NCBI chr 1:17,672,675...18,320,641
Ensembl chr 1:17,672,536...18,320,530 		JBrowse link
G Lamb1 laminin subunit beta 1 decreases expression ISO Isoproterenol results in decreased expression of LAMB1 mRNA CTD PMID:20003209 NCBI chr 6:47,835,492...47,902,585
Ensembl chr 6:47,835,525...47,902,585 		JBrowse link
G Lbh LBH regulator of WNT signaling pathway decreases expression ISO Isoproterenol results in decreased expression of LBH mRNA CTD PMID:20003209 NCBI chr 6:22,569,238...22,593,056
Ensembl chr 6:22,568,834...22,593,079 		JBrowse link
G Lbp lipopolysaccharide binding protein increases expression ISO Isoproterenol results in increased expression of LBP mRNA CTD PMID:20003209 PMID:21335049 NCBI chr 3:146,953,889...146,981,032
Ensembl chr 3:146,954,015...146,981,586 		JBrowse link
G Lcat lecithin cholesterol acyltransferase multiple interactions
decreases activity		 EXP [Quercetin co-treated with alpha-Tocopherol] inhibits the reaction [Isoproterenol results in decreased activity of LCAT protein]; alliin inhibits the reaction [Isoproterenol results in decreased activity of LCAT protein]; Desmodium gangeticum extract inhibits the reaction [Isoproterenol results in decreased activity of LCAT protein]; epigallocatechin gallate inhibits the reaction [Isoproterenol results in decreased activity of LCAT protein]; naringin inhibits the reaction [Isoproterenol results in decreased activity of LCAT protein] CTD PMID:15740881 PMID:16640830 PMID:16906524 PMID:19595682 PMID:20024955 NCBI chr19:33,834,748...33,838,214
Ensembl chr19:33,834,403...33,838,231 		JBrowse link
G Lcn2 lipocalin 2 multiple interactions
increases expression		 ISO Doxycycline inhibits the reaction [Isoproterenol results in increased expression of LCN2 mRNA] CTD PMID:18089841 PMID:20003209 NCBI chr 3:15,680,688...15,684,033
Ensembl chr 3:15,680,687...15,684,095 		JBrowse link
G Ldha lactate dehydrogenase A multiple interactions
increases expression
increases secretion		 EXP [Quercetin co-treated with alpha-Tocopherol] inhibits the reaction [Isoproterenol results in increased expression of LDHA protein]; Acetylcysteine inhibits the reaction [Isoproterenol results in increased expression of LDHA protein]; benidipine inhibits the reaction [Isoproterenol results in increased expression of and results in increased secretion of LDHA protein]; caffeic acid inhibits the reaction [Isoproterenol results in increased expression of LDHA protein]; Gallic Acid inhibits the reaction [Isoproterenol results in increased secretion of LDHA protein]; Isoproterenol results in increased expression of and results in increased secretion of LDHA protein; naringin inhibits the reaction [Isoproterenol results in increased expression of LDHA protein]; oleuropein inhibits the reaction [Isoproterenol results in increased expression of and results in increased secretion of LDHA protein] CTD PMID:17188415 PMID:19146839 PMID:21322096 PMID:21472895 PMID:21671307 More... NCBI chr 1:97,371,823...97,381,247
Ensembl chr 1:97,366,021...97,433,472 		JBrowse link
G Ldhb lactate dehydrogenase B multiple interactions
increases expression
increases secretion		 EXP [Quercetin co-treated with alpha-Tocopherol] inhibits the reaction [Isoproterenol results in increased expression of LDHB protein]; Acetylcysteine inhibits the reaction [Isoproterenol results in increased expression of LDHB protein]; caffeic acid inhibits the reaction [Isoproterenol results in increased expression of LDHB protein]; Gallic Acid inhibits the reaction [Isoproterenol results in increased secretion of LDHB protein]; naringin inhibits the reaction [Isoproterenol results in increased expression of LDHB protein] CTD PMID:17188415 PMID:19146839 PMID:21322096 PMID:21472895 PMID:21671307 NCBI chr 4:175,428,382...175,446,403
Ensembl chr 4:175,428,385...175,446,403 		JBrowse link
G Lep leptin decreases secretion
increases secretion
increases expression
multiple interactions		 ISO
EXP		 Isoproterenol results in decreased secretion of LEP protein
Isoproterenol results in increased secretion of LEP protein
Isoproterenol results in increased expression of LEP protein
CPU0213 inhibits the reaction [Isoproterenol results in increased expression of LEP protein]
Propranolol inhibits the reaction [Isoproterenol results in decreased secretion of LEP protein]		 CTD PMID:11022189 PMID:20307649 PMID:25111128 NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262 		JBrowse link
G Lepr leptin receptor multiple interactions
affects response to substance
increases expression		 EXP
ISO		 CPU0213 inhibits the reaction [Isoproterenol results in increased expression of LEPR mRNA]; CPU0213 inhibits the reaction [Isoproterenol results in increased expression of LEPR protein]
LEPR protein affects the susceptibility to Isoproterenol
Isoproterenol results in increased expression of LEPR mRNA; Isoproterenol results in increased expression of LEPR protein		 CTD PMID:20307649 PMID:36776448 NCBI chr 5:116,294,409...116,477,904
Ensembl chr 5:116,289,823...116,475,908 		JBrowse link
G Lgals3 galectin 3 increases expression ISO Isoproterenol results in increased expression of LGALS3 mRNA CTD PMID:20003209 NCBI chr15:20,620,083...20,632,019
Ensembl chr15:20,607,692...20,632,025 		JBrowse link
G Lgi1 leucine-rich, glioma inactivated 1 decreases expression ISO Isoproterenol results in decreased expression of LGI1 mRNA CTD PMID:20003209 NCBI chr 1:236,043,269...236,084,617
Ensembl chr 1:236,042,954...236,084,616 		JBrowse link
G Lgr6 leucine-rich repeat-containing G protein-coupled receptor 6 decreases expression ISO Isoproterenol results in decreased expression of LGR6 mRNA CTD PMID:20003209 NCBI chr13:46,424,382...46,544,074
Ensembl chr13:46,424,383...46,543,945 		JBrowse link
G Limd1 LIM domain containing 1 increases expression ISO Isoproterenol results in increased expression of LIMD1 mRNA CTD PMID:20003209 NCBI chr 8:123,121,363...123,168,476
Ensembl chr 8:123,122,460...123,167,714 		JBrowse link
G Lin7a lin-7 homolog A, crumbs cell polarity complex component increases expression ISO Isoproterenol results in increased expression of LIN7A mRNA CTD PMID:20003209 NCBI chr 7:42,586,704...42,742,609
Ensembl chr 7:42,586,719...42,730,550 		JBrowse link
G Lipe lipase E, hormone sensitive type increases phosphorylation
affects localization
multiple interactions
increases activity		 ISO
EXP		 Isoproterenol results in increased phosphorylation of LIPE protein
Isoproterenol affects the localization of LIPE protein
Papaverine inhibits the reaction [Isoproterenol affects the localization of LIPE protein]; Papaverine inhibits the reaction [Isoproterenol results in increased activity of LIPE protein]
Sirolimus promotes the reaction [Isoproterenol results in increased phosphorylation of LIPE protein]		 CTD PMID:10894095 PMID:11160373 PMID:21042876 NCBI chr 1:80,965,612...80,984,313
Ensembl chr 1:80,965,627...80,984,310 		JBrowse link
G Litaf lipopolysaccharide-induced TNF factor increases expression ISO Isoproterenol results in increased expression of LITAF mRNA CTD PMID:20003209 PMID:21335049 NCBI chr10:4,656,308...4,692,981
Ensembl chr10:4,625,552...4,692,763 		JBrowse link
G Lman1 lectin, mannose-binding, 1 increases expression ISO Isoproterenol results in increased expression of LMAN1 mRNA CTD PMID:21823215 NCBI chr18:59,508,996...59,530,873
Ensembl chr18:59,508,996...59,530,851 		JBrowse link
G Lmcd1 LIM and cysteine-rich domains 1 increases expression EXP Isoproterenol results in increased expression of LMCD1 mRNA CTD PMID:20211217 PMID:23558518 NCBI chr 4:145,393,153...145,452,049
Ensembl chr 4:145,393,145...145,452,046 		JBrowse link
G Lmod3 leiomodin 3 decreases expression ISO Isoproterenol results in decreased expression of LMOD3 mRNA CTD PMID:20003209 NCBI chr 4:129,843,964...129,858,684
Ensembl chr 4:129,843,970...129,858,244 		JBrowse link
G Lonrf3 LON peptidase N-terminal domain and ring finger 3 increases expression ISO Isoproterenol results in increased expression of LONRF3 mRNA CTD PMID:20003209 NCBI chr  X:115,565,214...115,603,886
Ensembl chr  X:115,565,267...115,598,809 		JBrowse link
G Lox lysyl oxidase increases expression ISO Isoproterenol results in increased expression of LOX mRNA CTD PMID:20003209 NCBI chr18:45,964,544...45,977,431
Ensembl chr18:45,967,343...46,041,477 		JBrowse link
G Lpl lipoprotein lipase multiple interactions
decreases expression
increases expression
decreases activity		 EXP
ISO		 cirazoline promotes the reaction [Isoproterenol results in increased expression of LPL mRNA]; naringin inhibits the reaction [Isoproterenol results in decreased activity of LPL protein]
Isoproterenol results in decreased expression of LPL mRNA		 CTD PMID:9032464 PMID:16906524 PMID:21335049 NCBI chr16:20,830,055...20,853,855
Ensembl chr16:20,829,465...20,855,249 		JBrowse link
G Lrat lecithin retinol acyltransferase decreases expression ISO Isoproterenol results in decreased expression of LRAT mRNA CTD PMID:20003209 NCBI chr 2:168,264,093...168,273,155
Ensembl chr 2:168,266,877...168,273,619 		JBrowse link
G Lrg1 leucine-rich alpha-2-glycoprotein 1 increases expression ISO Isoproterenol results in increased expression of LRG1 mRNA CTD PMID:20003209 NCBI chr 9:947,516...949,773
Ensembl chr 9:947,516...949,813 		JBrowse link
G Lrpprc leucine-rich pentatricopeptide repeat containing multiple interactions EXP [Isoproterenol co-treated with POSTN protein] results in decreased expression of LRPPRC mRNA CTD PMID:30303030 NCBI chr 6:9,859,816...9,942,294
Ensembl chr 6:9,859,867...9,942,293 		JBrowse link
G Lrrc52 leucine rich repeat containing 52 increases expression ISO Isoproterenol results in increased expression of LRRC52 mRNA CTD PMID:20003209 NCBI chr13:79,597,244...79,620,640
Ensembl chr13:79,597,245...79,620,640 		JBrowse link
G Lrrc58 leucine rich repeat containing 58 increases expression ISO Isoproterenol results in increased expression of LRRC58 mRNA CTD PMID:20003209 NCBI chr11:62,850,507...62,862,829
Ensembl chr11:62,847,562...62,862,829 		JBrowse link
G Lrrc8c leucine rich repeat containing 8 VRAC subunit C increases expression ISO Isoproterenol results in increased expression of LRRC8C mRNA CTD PMID:20003209 NCBI chr14:4,223,901...4,315,590
Ensembl chr14:4,227,832...4,315,249 		JBrowse link
G Lsm14a LSM14A mRNA processing body assembly factor increases expression ISO Isoproterenol results in increased expression of LSM14A mRNA CTD PMID:20003209 NCBI chr 1:86,964,800...87,009,325
Ensembl chr 1:86,964,828...87,009,276 		JBrowse link
G Lsm3 LSM3 homolog, U6 small nuclear RNA and mRNA degradation associated decreases expression ISO Isoproterenol results in decreased expression of LSM3 mRNA CTD PMID:20003209 NCBI chr 4:124,021,023...124,027,269
Ensembl chr 4:124,021,023...124,027,269 		JBrowse link
G Ltbp2 latent transforming growth factor beta binding protein 2 increases expression
increases expression 		ISO Isoproterenol results in increased expression of LTBP2 mRNA
Isoproterenol increases expression of Ltbp2 mRNA in the heart		 CTD
RGD		 PMID:20003209 PMID:29950403 RGD:156451654 NCBI chr 6:104,429,947...104,530,498
Ensembl chr 6:104,429,947...104,526,208 		JBrowse link
G Ly6a lymphocyte antigen 6 family member A increases expression ISO Isoproterenol results in increased expression of LY6A mRNA CTD PMID:20003209 NCBI chr 7:107,177,191...107,189,436
Ensembl chr 7:107,183,469...107,189,981 		JBrowse link
G Lyve1 lymphatic vessel endothelial hyaluronan receptor 1 increases expression ISO Isoproterenol results in increased expression of LYVE1 mRNA CTD PMID:20003209 NCBI chr 1:164,962,872...164,976,309
Ensembl chr 1:164,962,872...164,976,309 		JBrowse link
G Maf MAF bZIP transcription factor increases expression EXP Isoproterenol results in increased expression of MAF mRNA CTD PMID:30303030 NCBI chr19:43,353,867...43,713,162
Ensembl chr19:43,360,342...43,712,365 		JBrowse link
G Maff MAF bZIP transcription factor F increases expression ISO Isoproterenol results in increased expression of MAFF mRNA CTD PMID:20003209 NCBI chr 7:110,912,367...110,923,711
Ensembl chr 7:110,912,499...110,923,851 		JBrowse link
G Man1a1 mannosidase, alpha, class 1A, member 1 increases expression ISO Isoproterenol results in increased expression of MAN1A mRNA CTD PMID:20003209 NCBI chr20:33,202,509...33,385,747
Ensembl chr20:33,202,517...33,385,824 		JBrowse link
G Man2a1 mannosidase, alpha, class 2A, member 1 increases expression ISO Isoproterenol results in increased expression of MAN2A1 mRNA CTD PMID:20003209 NCBI chr 9:104,252,001...104,408,349
Ensembl chr 9:104,252,001...104,408,349 		JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 multiple interactions EXP
ISO		 MAP2K1 protein affects the reaction [Isoproterenol results in increased expression of NPPA mRNA]; MAP2K1 protein affects the reaction [Isoproterenol results in increased phosphorylation of and results in increased activity of MAPK1 protein]; MAP2K1 protein affects the reaction [Isoproterenol results in increased phosphorylation of and results in increased activity of MAPK3 protein]
MAP2K1 protein promotes the reaction [Isoproterenol results in decreased expression of COL2A1 mRNA]; MAP2K1 protein promotes the reaction [Isoproterenol results in decreased expression of COL2A1 protein]; MAP2K1 protein promotes the reaction [Isoproterenol results in increased phosphorylation of MAPK1 protein]; MAP2K1 protein promotes the reaction [Isoproterenol results in increased phosphorylation of MAPK3 protein]		 CTD PMID:10888249 PMID:21177286 NCBI chr 8:64,683,449...64,754,900
Ensembl chr 8:64,683,449...64,755,147 		JBrowse link
G Map2k4 mitogen activated protein kinase kinase 4 multiple interactions EXP [Isoproterenol co-treated with POSTN protein] results in decreased expression of MAP2K4 mRNA CTD PMID:30303030 NCBI chr10:50,343,227...50,447,956
Ensembl chr10:50,344,915...50,447,993 		JBrowse link
G Map3k2 mitogen activated protein kinase kinase kinase 2 multiple interactions
decreases expression		 EXP [Isoproterenol co-treated with POSTN protein] results in decreased expression of MAP3K2 mRNA
Isoproterenol results in decreased expression of MAP3K2 mRNA		 CTD PMID:30303030 NCBI chr18:23,807,218...23,879,722
Ensembl chr18:23,807,218...23,871,433 		JBrowse link
G Map3k5 mitogen-activated protein kinase kinase kinase 5 decreases expression ISO Isoproterenol results in decreased expression of MAP3K5 mRNA CTD PMID:21335049 NCBI chr 1:14,685,776...14,904,935
Ensembl chr 1:14,685,492...14,904,800 		JBrowse link
G Map3k6 mitogen-activated protein kinase kinase kinase 6 multiple interactions
increases expression		 ISO Doxycycline inhibits the reaction [Isoproterenol results in increased expression of MAP3K6 mRNA] CTD PMID:18089841 PMID:20003209 NCBI chr 5:145,440,126...145,452,213
Ensembl chr 5:145,440,346...145,452,212 		JBrowse link
G Map3k8 mitogen-activated protein kinase kinase kinase 8 multiple interactions
increases expression		 ISO Doxycycline inhibits the reaction [Isoproterenol results in increased expression of MAP3K8 mRNA] CTD PMID:18089841 PMID:20003209 NCBI chr17:53,382,908...53,403,216
Ensembl chr17:53,383,131...53,403,216 		JBrowse link
G Map7 microtubule-associated protein 7 increases expression ISO Isoproterenol results in increased expression of MAP7 mRNA CTD PMID:20003209 NCBI chr 1:14,910,433...15,037,574
Ensembl chr 1:14,910,551...15,037,574 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 increases activity
increases phosphorylation
multiple interactions		 ISO
EXP		 Isoproterenol results in increased activity of MAPK1 protein
Isoproterenol results in increased phosphorylation of MAPK1 protein
DUSP1 protein inhibits the reaction [Isoproterenol results in increased phosphorylation of MAPK1 protein]; MAP2K1 protein promotes the reaction [Isoproterenol results in increased phosphorylation of MAPK1 protein]
erdosteine inhibits the reaction [Isoproterenol results in increased expression of and results in increased phosphorylation of MAPK1 protein]; Isoproterenol inhibits the reaction [AGT protein results in increased phosphorylation of MAPK1 protein]; Isoproterenol results in increased expression of and results in increased phosphorylation of MAPK1 protein; Isoproterenol results in increased phosphorylation of and results in increased activity of MAPK1 protein; MAP2K1 protein affects the reaction [Isoproterenol results in increased phosphorylation of and results in increased activity of MAPK1 protein]; MIR214 mRNA promotes the reaction [Isoproterenol results in increased phosphorylation of MAPK1 protein]; Propranolol inhibits the reaction [Isoproterenol results in increased activity of MAPK1 protein]; SL 327 inhibits the reaction [Isoproterenol results in increased phosphorylation of MAPK1 protein]
[Isoproterenol binds to ADRB2 protein] which results in increased phosphorylation of MAPK1 protein; [Isoproterenol binds to and results in increased activity of ADRB2 protein] which results in increased phosphorylation of and results in increased activity of MAPK1 protein; ARRB2 protein promotes the reaction [Isoproterenol results in increased phosphorylation of MAPK1 protein]; Isoproterenol inhibits the reaction [Estradiol results in decreased phosphorylation of MAPK1 protein]		 CTD PMID:10888249 PMID:11093795 PMID:15292328 PMID:16980553 PMID:17623046 More... NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk14 mitogen activated protein kinase 14 multiple interactions
increases phosphorylation		 ISO Doxycycline inhibits the reaction [Isoproterenol results in increased phosphorylation of MAPK14 protein] CTD PMID:18089841 NCBI chr20:6,749,646...6,810,590
Ensembl chr20:6,749,670...6,810,589 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions
increases expression
increases phosphorylation
increases activity		 ISO
EXP		 [Isoproterenol binds to ADRB2 protein] which results in increased phosphorylation of MAPK3 protein; [Isoproterenol binds to and results in increased activity of ADRB2 protein] which results in increased phosphorylation of and results in increased activity of MAPK3 protein; ARRB2 protein promotes the reaction [Isoproterenol results in increased phosphorylation of MAPK3 protein]; Isoproterenol inhibits the reaction [Estradiol results in decreased phosphorylation of MAPK3 protein]
Isoproterenol results in increased expression of MAPK3 mRNA
DUSP1 protein inhibits the reaction [Isoproterenol results in increased phosphorylation of MAPK3 protein]; MAP2K1 protein promotes the reaction [Isoproterenol results in increased phosphorylation of MAPK3 protein]
erdosteine inhibits the reaction [Isoproterenol results in increased expression of and results in increased phosphorylation of MAPK3 protein]; geraniol inhibits the reaction [Isoproterenol results in increased expression of MAPK3 mRNA]; geraniol inhibits the reaction [Isoproterenol results in increased phosphorylation of MAPK3 protein]; Isoproterenol inhibits the reaction [AGT protein results in increased phosphorylation of MAPK3 protein]; Isoproterenol results in increased expression of and results in increased phosphorylation of MAPK3 protein; Isoproterenol results in increased phosphorylation of and results in increased activity of MAPK3 protein; MAP2K1 protein affects the reaction [Isoproterenol results in increased phosphorylation of and results in increased activity of MAPK3 protein]; MIR214 mRNA promotes the reaction [Isoproterenol results in increased phosphorylation of MAPK3 protein]; Propranolol inhibits the reaction [Isoproterenol results in increased activity of MAPK3 protein]; SL 327 inhibits the reaction [Isoproterenol results in increased phosphorylation of MAPK3 protein]		 CTD PMID:10888249 PMID:11093795 PMID:15292328 PMID:16980553 PMID:17623046 More... NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions
increases expression
increases activity
increases phosphorylation		 ISO
EXP		 candesartan inhibits the reaction [Isoproterenol results in increased phosphorylation of MAPK8 protein]
Isoproterenol results in increased expression of MAPK8 mRNA
Isoproterenol results in increased activity of MAPK8 protein
2-((2-piperidin-1-ylethyl)thio)quinazolin-4(3H)-one inhibits the reaction [Isoproterenol results in increased phosphorylation of MAPK8 protein]; geraniol inhibits the reaction [Isoproterenol results in increased expression of MAPK8 mRNA]; geraniol inhibits the reaction [Isoproterenol results in increased phosphorylation of MAPK8 protein]		 CTD PMID:10591028 PMID:15951400 PMID:20562518 PMID:35608392 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981 		JBrowse link
G Marchf7 membrane associated ring-CH-type finger 7 increases expression ISO Isoproterenol results in increased expression of MARCHF7 mRNA CTD PMID:20003209 NCBI chr 3:44,680,229...44,720,172
Ensembl chr 3:44,681,632...44,720,168 		JBrowse link
G Mas1 MAS1 proto-oncogene, G protein-coupled receptor decreases expression EXP Isoproterenol results in decreased expression of MAS1 protein CTD PMID:20409916 NCBI chr 1:47,879,956...47,911,500
Ensembl chr 1:47,880,309...47,911,709 		JBrowse link
G Mb myoglobin increases expression
multiple interactions
increases secretion		 EXP Isoproterenol results in increased expression of MB protein
sinapinic acid inhibits the reaction [Isoproterenol results in increased expression of MB protein]
Isoproterenol results in increased secretion of MB protein		 CTD PMID:533011 PMID:19628585 PMID:32627257 NCBI chr 7:108,759,903...108,767,134
Ensembl chr 7:108,759,904...108,767,383 		JBrowse link
G Mbd1 methyl-CpG binding domain protein 1 increases expression ISO Isoproterenol results in increased expression of MBD1 mRNA CTD PMID:20003209 NCBI chr18:67,869,870...67,884,501
Ensembl chr18:67,869,992...67,886,554 		JBrowse link
G Mbd5 methyl-CpG binding domain protein 5 increases expression ISO Isoproterenol results in increased expression of MBD5 mRNA CTD PMID:20003209 NCBI chr 3:33,588,854...33,738,730
Ensembl chr 3:33,333,554...33,730,156 		JBrowse link
G Mccc2 methylcrotonyl-CoA carboxylase subunit 2 decreases expression ISO Isoproterenol results in decreased expression of MCCC2 mRNA CTD PMID:20003209 NCBI chr 2:31,304,927...31,375,978
Ensembl chr 2:31,304,932...31,375,972