CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: glutaraldehyde
Accession: CHEBI:64276
browse the term
Definition: A dialdehyde comprised of pentane with aldehyde functions at C-1 and C-5.
Synonyms: related_synonym: 1,3-Diformylpropane; 1,5-Pentanedial; 1,5-Pentanedione; Formula=C5H8O2; Glutardialdehyde; Glutaric acid dialdehyde; Glutaric dialdehyde; InChI=1S/C5H8O2/c6-4-2-1-3-5-7/h4-5H,1-3H2; InChIKey=SXRSQZLOMIGNAQ-UHFFFAOYSA-N; PENTANEDIAL; SMILES=O=CCCCC=O; glutaral; glutaralum
alt_id: CHEBI:45072
xref: CAS:111-30-8; Drug_Central:3267; HMDB:HMDB0029599; KEGG:C12518; KEGG:D01120
xref_mesh: MESH:D005976
xref: PDBeChem:PTD; PMID:10672649; PMID:11378863; PMID:22020189; PMID:22221459; PMID:22233542; PMID:22266295; PMID:22269730; PMID:22348538; PMID:22351440; PMID:24332617; PMID:7701454; PMID:9582689; PPDB:1567; Reaxys:605390; Wikipedia:Glutaraldehyde
G
Atf4
activating transcription factor 4
increases expression
ISO
Glutaral results in increased expression of ATF4 mRNA
CTD
PMID:28236482
NCBI chr 7:113,684,681...113,686,739
Ensembl chr 7:113,684,681...113,686,739
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Casp8
caspase 8
decreases expression
ISO
Glutaral results in decreased expression of CASP8 mRNA
CTD
PMID:28236482
NCBI chr 9:67,747,109...67,806,699
Ensembl chr 9:67,758,033...67,806,699
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Ccl4
C-C motif chemokine ligand 4
increases expression
ISO
Glutaral results in increased expression of CCL4 mRNA
CTD
PMID:20713136
NCBI chr10:68,963,893...68,965,728
Ensembl chr10:68,950,289...68,965,722
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Cd86
CD86 molecule
increases expression
ISO
Glutaral results in increased expression of CD86 protein
CTD
PMID:19665512
NCBI chr11:77,647,565...77,706,178
Ensembl chr11:77,647,600...77,725,361
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G6pd
glucose-6-phosphate dehydrogenase
decreases activity
ISO
Glutaral results in decreased activity of G6PD protein
CTD
PMID:19490936
NCBI chr X:157,352,364...157,372,144
Ensembl chr X:157,352,373...157,372,144
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Gja1
gap junction protein, alpha 1
decreases expression
EXP
Glutaral results in decreased expression of GJA1 protein
CTD
PMID:19932693
NCBI chr20:36,302,490...36,315,010
Ensembl chr20:36,302,352...36,319,689
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Gsr
glutathione-disulfide reductase
decreases activity multiple interactions
ISO
Glutaral results in decreased activity of GSR protein Idarubicin promotes the reaction [Glutaral results in decreased activity of GSR protein]
CTD
PMID:19490936
NCBI chr16:65,185,574...65,228,742
Ensembl chr16:65,185,574...65,228,394
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Il1r2
interleukin 1 receptor type 2
increases expression
ISO
Glutaral results in increased expression of IL1R2 mRNA
CTD
PMID:20713136
NCBI chr 9:49,879,928...49,920,374
Ensembl chr 9:49,877,266...49,920,374
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Il6
interleukin 6
affects expression
ISO
Glutaral affects the expression of IL6 mRNA
CTD
PMID:20200221
NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610
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Muc1
mucin 1, cell surface associated
decreases expression increases expression
ISO
Glutaral results in decreased expression of MUC1 protein Glutaral results in increased expression of MUC1 protein
CTD
PMID:38360295
NCBI chr 2:176,933,312...176,938,497
Ensembl chr 2:176,933,047...176,938,491
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Pmaip1
phorbol-12-myristate-13-acetate-induced protein 1
increases expression
ISO
Glutaral results in increased expression of PMAIP1 mRNA
CTD
PMID:20713136
NCBI chr18:62,255,970...62,262,384
Ensembl chr18:62,255,598...62,262,382
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Tnf
tumor necrosis factor
affects expression increases expression
ISO
Glutaral affects the expression of TNF mRNA Glutaral results in increased expression of TNF mRNA
CTD
PMID:20200221 PMID:28236482
NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303
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Tp53
tumor protein p53
decreases expression
ISO
Glutaral results in decreased expression of TP53 mRNA
CTD
PMID:28236482
NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299
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