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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:glutaraldehyde
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Accession:CHEBI:64276 term browser browse the term
Definition:A dialdehyde comprised of pentane with aldehyde functions at C-1 and C-5.
Synonyms:related_synonym: 1,3-Diformylpropane;   1,5-Pentanedial;   1,5-Pentanedione;   Formula=C5H8O2;   Glutardialdehyde;   Glutaric acid dialdehyde;   Glutaric dialdehyde;   InChI=1S/C5H8O2/c6-4-2-1-3-5-7/h4-5H,1-3H2;   InChIKey=SXRSQZLOMIGNAQ-UHFFFAOYSA-N;   PENTANEDIAL;   SMILES=O=CCCCC=O;   glutaral;   glutaralum
 alt_id: CHEBI:45072
 xref: CAS:111-30-8;   Drug_Central:3267;   HMDB:HMDB0029599;   KEGG:C12518;   KEGG:D01120
 xref_mesh: MESH:D005976
 xref: PDBeChem:PTD;   PMID:10672649;   PMID:11378863;   PMID:22020189;   PMID:22221459;   PMID:22233542;   PMID:22266295;   PMID:22269730;   PMID:22348538;   PMID:22351440;   PMID:24332617;   PMID:7701454;   PMID:9582689;   PPDB:1567;   Reaxys:605390;   Wikipedia:Glutaraldehyde



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glutaraldehyde term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atf4 activating transcription factor 4 increases expression ISO Glutaral results in increased expression of ATF4 mRNA CTD PMID:28236482 NCBI chr 7:113,684,681...113,686,739
Ensembl chr 7:113,684,681...113,686,739
JBrowse link
G Casp8 caspase 8 decreases expression ISO Glutaral results in decreased expression of CASP8 mRNA CTD PMID:28236482 NCBI chr 9:67,747,109...67,806,699
Ensembl chr 9:67,758,033...67,806,699
JBrowse link
G Ccl4 C-C motif chemokine ligand 4 increases expression ISO Glutaral results in increased expression of CCL4 mRNA CTD PMID:20713136 NCBI chr10:68,963,893...68,965,728
Ensembl chr10:68,950,289...68,965,722
JBrowse link
G Cd86 CD86 molecule increases expression ISO Glutaral results in increased expression of CD86 protein CTD PMID:19665512 NCBI chr11:77,647,565...77,706,178
Ensembl chr11:77,647,600...77,725,361
JBrowse link
G G6pd glucose-6-phosphate dehydrogenase decreases activity ISO Glutaral results in decreased activity of G6PD protein CTD PMID:19490936 NCBI chr  X:157,352,364...157,372,144
Ensembl chr  X:157,352,373...157,372,144
JBrowse link
G Gja1 gap junction protein, alpha 1 decreases expression EXP Glutaral results in decreased expression of GJA1 protein CTD PMID:19932693 NCBI chr20:36,302,490...36,315,010
Ensembl chr20:36,302,352...36,319,689
JBrowse link
G Gsr glutathione-disulfide reductase decreases activity
multiple interactions
ISO Glutaral results in decreased activity of GSR protein
Idarubicin promotes the reaction [Glutaral results in decreased activity of GSR protein]
CTD PMID:19490936 NCBI chr16:65,185,574...65,228,742
Ensembl chr16:65,185,574...65,228,394
JBrowse link
G Il1r2 interleukin 1 receptor type 2 increases expression ISO Glutaral results in increased expression of IL1R2 mRNA CTD PMID:20713136 NCBI chr 9:49,879,928...49,920,374
Ensembl chr 9:49,877,266...49,920,374
JBrowse link
G Il6 interleukin 6 affects expression ISO Glutaral affects the expression of IL6 mRNA CTD PMID:20200221 NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610
JBrowse link
G Muc1 mucin 1, cell surface associated decreases expression
increases expression
ISO Glutaral results in decreased expression of MUC1 protein
Glutaral results in increased expression of MUC1 protein
CTD PMID:38360295 NCBI chr 2:176,933,312...176,938,497
Ensembl chr 2:176,933,047...176,938,491
JBrowse link
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 increases expression ISO Glutaral results in increased expression of PMAIP1 mRNA CTD PMID:20713136 NCBI chr18:62,255,970...62,262,384
Ensembl chr18:62,255,598...62,262,382
JBrowse link
G Tnf tumor necrosis factor affects expression
increases expression
ISO Glutaral affects the expression of TNF mRNA
Glutaral results in increased expression of TNF mRNA
CTD PMID:20200221 PMID:28236482 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303
JBrowse link
G Tp53 tumor protein p53 decreases expression ISO Glutaral results in decreased expression of TP53 mRNA CTD PMID:28236482 NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20862
    role 20820
      biological role 20818
        fixative 50
          glutaraldehyde 13
Path 2
Term Annotations click to browse term
  CHEBI ontology 20862
    subatomic particle 20860
      composite particle 20860
        hadron 20860
          baryon 20860
            nucleon 20860
              atomic nucleus 20860
                atom 20860
                  main group element atom 20781
                    p-block element atom 20781
                      carbon group element atom 20715
                        carbon atom 20710
                          organic molecular entity 20710
                            heteroorganic entity 20219
                              organochalcogen compound 19904
                                organooxygen compound 19806
                                  carbon oxoacid 19155
                                    carboxylic acid 19152
                                      carboacyl group 18085
                                        univalent carboacyl group 18085
                                          formyl group 9407
                                            aldehyde 9407
                                              dialdehyde 143
                                                glutaraldehyde 13
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