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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:NAN 190 hydrobromide
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Accession:CHEBI:64123 term browser browse the term
Definition:A hydrobromide obtained by reaction of NAN 190 with one equivalent of hydrobromic acid.
Synonyms:exact_synonym: 2-{4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl}-1H-isoindole-1,3(2H)-dione hydrobromide
 related_synonym: 1-(2-Methoxyphenyl)-4-(4-(2-phthalimido)butyl)piperazine hydrobromide;   1-[4-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)butyl]-4-(2-methoxyphenyl)piperazin-1-ium bromide;   Formula=C23H28BrN3O3;   InChI=1S/C23H27N3O3.BrH/c1-29-21-11-5-4-10-20(21)25-16-14-24(15-17-25)12-6-7-13-26-22(27)18-8-2-3-9-19(18)23(26)28;/h2-5,8-11H,6-7,12-17H2,1H3;1H;   InChIKey=AXRUEPFPTQYHQD-UHFFFAOYSA-N;   NAN190 hydrobromide;   Nan 190;   SMILES=Br.COc1ccccc1N1CCN(CCCCN2C(=O)c3ccccc3C2=O)CC1
 xref: CAS:115338-32-4
 xref_mesh: MESH:C058895
 xref: Reaxys:4775818


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NAN 190 hydrobromide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Htr1a 5-hydroxytryptamine receptor 1A multiple interactions EXP
ISO		 [1-(2-methoxyphenyl)-4-(4-(2-phthalimido)butyl)piperazine binds to and results in decreased activity of HTR1A protein] which results in decreased susceptibility to Serotonin
[1-(2-methoxyphenyl)-4-(4-(2-phthalimido)butyl)piperazine binds to and results in decreased activity of HTR1A protein] which results in decreased susceptibility to Methamphetamine		 CTD PMID:15213358 PMID:15482641 PMID:16528294 NCBI chr 2:36,693,462...36,698,026
Ensembl chr 2:36,694,174...36,695,442 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19901
    chemical entity 19899
      molecular entity 19899
        ion 17100
          cation 16891
            organic cation 8962
              NAN 190(1+) 1
                NAN 190 hydrobromide 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19901
    subatomic particle 19899
      composite particle 19899
        hadron 19899
          baryon 19899
            nucleon 19899
              atomic nucleus 19899
                atom 19899
                  main group element atom 19838
                    main group molecular entity 19838
                      s-block molecular entity 19672
                        hydrogen molecular entity 19654
                          hydrides 19163
                            inorganic hydride 18182
                              pnictogen hydride 18172
                                nitrogen hydride 18085
                                  ammonium 8318
                                    ammonium ion derivative 8313
                                      NAN 190(1+) 1
                                        NAN 190 hydrobromide 1
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