CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: valdecoxib
Accession: CHEBI:63634
browse the term
Definition: A member of the class of isoxazoles that is isoxazole which is substituted at positions 3, 4 and 5 by phenyl, p-sulfamoylphenyl and methyl groups, respectively. A selective cyclooxygenase 2-inhibitor, it used as a nonsteroidal anti-inflammatory drug (NSAID) for the treatment of arthritis from 2001 until 2005, when it was withdrawn following concerns of an associated increased risk of heart attack and stroke.
Synonyms: exact_synonym: 4-(5-methyl-3-phenyl-1,2-oxazol-4-yl)benzenesulfonamide
related_synonym: 4-(5-Methyl-3-phenyl-4-isoxazolyl)benzenesulfonamide; Bextra; Formula=C16H14N2O3S; InChI=1S/C16H14N2O3S/c1-11-15(12-7-9-14(10-8-12)22(17,19)20)16(18-21-11)13-5-3-2-4-6-13/h2-10H,1H3,(H2,17,19,20); InChIKey=LNPDTQAFDNKSHK-UHFFFAOYSA-N; SMILES=Cc1onc(-c2ccccc2)c1-c1ccc(cc1)S(N)(=O)=O; p-(5-Methyl-3-phenyl-4-isoxazolyl)benzenesulfonamide; valdecoxibum
alt_id: CHEBI:41662
xref: CAS:181695-72-7; DrugBank:DB00580; Drug_Central:2799; HMDB:HMDB0005033; KEGG:D02709; LINCS:LSM-5305
xref_mesh: MESH:C406224
xref: PDBeChem:COX; PMID:20467258; PMID:20717044; PMID:21073910; PMID:21720517; PMID:21769548; Reaxys:8563786; Wikipedia:Valdecoxib
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Aadac
arylacetamide deacetylase
decreases expression
EXP
valdecoxib results in decreased expression of AADAC mRNA
CTD
PMID:24136188
NCBI chr 2:144,163,436...144,186,086
Ensembl chr 2:144,135,319...144,174,734
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Abcb1a
ATP binding cassette subfamily B member 1A
increases expression
EXP
valdecoxib results in increased expression of ABCB1 mRNA
CTD
PMID:24136188
NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
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Abcb4
ATP binding cassette subfamily B member 4
increases expression
EXP
valdecoxib results in increased expression of ABCB4 mRNA
CTD
PMID:24136188
NCBI chr 4:25,150,998...25,209,489
Ensembl chr 4:25,151,953...25,209,202
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Abcc2
ATP binding cassette subfamily C member 2
increases expression
EXP
valdecoxib results in increased expression of ABCC2 mRNA
CTD
PMID:24136188
NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238
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Abcc3
ATP binding cassette subfamily C member 3
increases expression
EXP
valdecoxib results in increased expression of ABCC3 mRNA
CTD
PMID:24136188
NCBI chr10:79,296,681...79,342,749
Ensembl chr10:79,296,693...79,342,595
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Abcc8
ATP binding cassette subfamily C member 8
decreases expression
EXP
valdecoxib results in decreased expression of ABCC8 mRNA
CTD
PMID:24136188
NCBI chr 1:96,598,568...96,679,563
Ensembl chr 1:96,598,647...96,679,510
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Abcc9
ATP binding cassette subfamily C member 9
decreases expression
EXP
valdecoxib results in decreased expression of ABCC9 mRNA
CTD
PMID:24136188
NCBI chr 4:175,531,854...175,655,849
Ensembl chr 4:175,532,547...175,655,356
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Abcg5
ATP binding cassette subfamily G member 5
increases expression
EXP
valdecoxib results in increased expression of ABCG5 mRNA
CTD
PMID:24136188
NCBI chr 6:9,965,118...9,990,563
Ensembl chr 6:9,965,118...9,990,563
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Abhd4
abhydrolase domain containing 4, N-acyl phospholipase B
increases expression
EXP
valdecoxib results in increased expression of ABHD4 mRNA
CTD
PMID:24136188
NCBI chr15:27,697,384...27,716,013
Ensembl chr15:27,704,113...27,716,966
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Acaca
acetyl-CoA carboxylase alpha
decreases expression
EXP
valdecoxib results in decreased expression of ACACA mRNA
CTD
PMID:24136188
NCBI chr10:69,014,261...69,276,453
Ensembl chr10:69,014,170...69,276,457
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Acat2
acetyl-CoA acetyltransferase 2
increases expression
EXP
valdecoxib results in increased expression of ACAT2 mRNA
CTD
PMID:24136188
NCBI chr 1:47,695,833...47,713,879
Ensembl chr 1:47,695,788...47,752,821
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Acbd6
acyl-CoA binding domain containing 6
increases expression
EXP
valdecoxib results in increased expression of ACBD6 mRNA
CTD
PMID:24136188
NCBI chr13:67,726,786...67,863,392
Ensembl chr13:67,726,786...67,862,311
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Acly
ATP citrate lyase
decreases expression
EXP
valdecoxib results in decreased expression of ACLY mRNA
CTD
PMID:24136188
NCBI chr10:85,412,045...85,464,253
Ensembl chr10:85,412,049...85,463,320
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Aco1
aconitase 1
increases expression
EXP
valdecoxib results in increased expression of ACO1 mRNA
CTD
PMID:24136188
NCBI chr 5:55,259,841...55,315,872
Ensembl chr 5:55,259,827...55,316,391
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Acot13
acyl-CoA thioesterase 13
decreases expression
EXP
valdecoxib results in decreased expression of ACOT13 mRNA
CTD
PMID:24136188
NCBI chr17:40,240,378...40,252,851
Ensembl chr17:40,240,378...40,252,851
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Acot2
acyl-CoA thioesterase 2
increases expression
EXP
valdecoxib results in increased expression of ACOT2 mRNA
CTD
PMID:24136188
NCBI chr 6:103,611,738...103,619,404
Ensembl chr 6:103,611,544...103,619,245
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Acot4
acyl-CoA thioesterase 4
increases expression
EXP
valdecoxib results in increased expression of ACOT4 mRNA
CTD
PMID:24136188
NCBI chr 6:103,668,699...103,674,037
Ensembl chr 6:103,668,753...103,673,917
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Acox3
acyl-CoA oxidase 3, pristanoyl
decreases expression
EXP
valdecoxib results in decreased expression of ACOX3 mRNA
CTD
PMID:24136188
NCBI chr14:75,133,986...75,176,767
Ensembl chr14:75,094,676...75,176,205
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Acsl5
acyl-CoA synthetase long-chain family member 5
decreases expression
EXP
valdecoxib results in decreased expression of ACSL5 mRNA
CTD
PMID:24136188
NCBI chr 1:254,289,513...254,336,608
Ensembl chr 1:254,292,521...254,336,607
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Actl6a
actin-like 6A
increases expression
EXP
valdecoxib results in increased expression of ACTL6A mRNA
CTD
PMID:24136188
NCBI chr 2:115,492,374...115,508,401
Ensembl chr 2:115,492,285...115,508,401
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Adam15
ADAM metallopeptidase domain 15
decreases expression
EXP
valdecoxib results in decreased expression of ADAM15 mRNA
CTD
PMID:24136188
NCBI chr 2:174,754,629...174,765,136
Ensembl chr 2:174,754,633...174,765,113
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Adamts9
ADAM metallopeptidase with thrombospondin type 1 motif, 9
decreases expression
EXP
valdecoxib results in decreased expression of ADAMTS9 mRNA
CTD
PMID:24136188
NCBI chr 4:125,290,633...125,462,988
Ensembl chr 4:125,291,490...125,462,929
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Adamtsl4
ADAMTS-like 4
increases expression
EXP
valdecoxib results in increased expression of ADAMTSL4 mRNA
CTD
PMID:24136188
NCBI chr 2:183,235,634...183,247,091
Ensembl chr 2:183,235,646...183,246,848
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Adgrv1
adhesion G protein-coupled receptor V1
decreases expression
EXP
valdecoxib results in decreased expression of ADGRV1 mRNA
CTD
PMID:24136188
NCBI chr 2:11,331,434...11,911,713
Ensembl chr 2:11,331,442...11,911,688
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Adh1c
alcohol dehydrogenase 1C (class I), gamma polypeptide
decreases expression
EXP
valdecoxib results in decreased expression of ADH1 mRNA
CTD
PMID:24136188
NCBI chr 2:226,797,303...226,808,892
Ensembl chr 2:226,797,303...226,808,892
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Adhfe1
alcohol dehydrogenase, iron containing, 1
decreases expression
EXP
valdecoxib results in decreased expression of ADHFE1 mRNA
CTD
PMID:24136188
NCBI chr 5:9,705,966...9,732,580
Ensembl chr 5:9,705,970...9,732,517
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Adipor2
adiponectin receptor 2
decreases expression
EXP
valdecoxib results in decreased expression of ADIPOR2 mRNA
CTD
PMID:24136188
NCBI chr 4:152,524,604...152,588,848
Ensembl chr 4:152,524,623...152,559,355
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Adrm1
ADRM1 26S proteasome ubiquitin receptor
increases expression
EXP
valdecoxib results in increased expression of ADRM1 mRNA
CTD
PMID:24136188
NCBI chr 3:167,265,435...167,270,197
Ensembl chr 3:167,265,296...167,270,195
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Agxt
alanine--glyoxylate aminotransferase
decreases expression
EXP
valdecoxib results in decreased expression of AGXT mRNA
CTD
PMID:24136188
NCBI chr 9:93,675,384...93,685,337
Ensembl chr 9:93,675,384...93,685,336
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Ahsa1
activator of Hsp90 ATPase activity 1
increases expression
EXP
valdecoxib results in increased expression of AHSA1 mRNA
CTD
PMID:24136188
NCBI chr 6:106,913,296...106,921,347
Ensembl chr 6:106,913,530...106,921,345
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Aig1
androgen-induced 1
increases expression
EXP
valdecoxib results in increased expression of AIG1 mRNA
CTD
PMID:24136188
NCBI chr 1:8,046,430...8,269,276
Ensembl chr 1:8,046,430...8,269,084
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Akap8l
A-kinase anchoring protein 8 like
decreases expression
EXP
valdecoxib results in decreased expression of AKAP8L mRNA
CTD
PMID:24136188
NCBI chr 7:11,332,671...11,362,287
Ensembl chr 7:11,332,672...11,362,275
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Akr1c1
aldo-keto reductase family 1, member C1
decreases expression
EXP
valdecoxib results in decreased expression of AKR1C1 mRNA
CTD
PMID:24136188
NCBI chr17:65,810,474...65,837,385
Ensembl chr17:65,810,475...65,837,326
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Akr7a3
aldo-keto reductase family 7 member A3
increases expression
EXP
valdecoxib results in increased expression of AKR7A3 mRNA
CTD
PMID:24136188
NCBI chr 5:151,590,968...151,601,394
Ensembl chr 5:151,584,479...151,601,394
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Alas1
5'-aminolevulinate synthase 1
increases expression
EXP
valdecoxib results in increased expression of ALAS1 mRNA
CTD
PMID:24136188
NCBI chr 8:106,876,514...106,889,917
Ensembl chr 8:106,876,514...106,889,917
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Aldh1a1
aldehyde dehydrogenase 1 family, member A1
increases expression
EXP
valdecoxib results in increased expression of ALDH1A1 mRNA
CTD
PMID:24136188
NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961
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Aldh1b1
aldehyde dehydrogenase 1 family, member B1
decreases expression
EXP
valdecoxib results in decreased expression of ALDH1B1 mRNA
CTD
PMID:24136188
NCBI chr 5:60,063,370...60,068,378
Ensembl chr 5:60,063,225...60,068,378
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Als2cl
ALS2 C-terminal like
increases expression
EXP
valdecoxib results in increased expression of ALS2CL mRNA
CTD
PMID:24136188
NCBI chr 8:110,863,753...110,884,434
Ensembl chr 8:110,864,975...110,884,419
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Ankhd1
ankyrin repeat and KH domain containing 1
decreases expression
EXP
valdecoxib results in decreased expression of ANKHD1-EIF4EBP3 mRNA
CTD
PMID:24136188
NCBI chr18:28,161,882...28,260,917
Ensembl chr18:28,162,311...28,268,024
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Ankle2
ankyrin repeat and LEM domain containing 2
increases expression
EXP
valdecoxib results in increased expression of ANKLE2 mRNA
CTD
PMID:24136188
NCBI chr12:46,418,142...46,451,304
Ensembl chr12:46,417,759...46,500,514
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Anxa7
annexin A7
increases expression
EXP
valdecoxib results in increased expression of ANXA7 mRNA
CTD
PMID:24136188
NCBI chr15:3,821,798...3,849,659
Ensembl chr15:3,821,845...3,849,385
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Ap2m1
adaptor related protein complex 2 subunit mu 1
increases expression
EXP
valdecoxib results in increased expression of AP2M1 mRNA
CTD
PMID:24136188
NCBI chr11:80,355,307...80,364,218
Ensembl chr11:80,328,041...80,364,140
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Apeg3
antisense paternally expressed gene 3
increases expression
EXP
valdecoxib results in increased expression of APEG3 mRNA
CTD
PMID:24136188
NCBI chr 1:67,121,402...67,122,333
Ensembl chr 1:67,121,900...67,122,181 Ensembl chr 1:67,121,900...67,122,181
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Aplp2
amyloid beta precursor like protein 2
decreases expression
EXP
valdecoxib results in decreased expression of APLP2 mRNA
CTD
PMID:24136188
NCBI chr 8:29,599,230...29,662,311
Ensembl chr 8:29,599,230...29,661,855
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Apmap
adipocyte plasma membrane associated protein
decreases expression
EXP
valdecoxib results in decreased expression of APMAP mRNA
CTD
PMID:24136188
NCBI chr 3:139,409,021...139,437,296
Ensembl chr 3:139,409,022...139,437,341
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Apoa4
apolipoprotein A4
decreases expression
EXP
valdecoxib results in decreased expression of APOA4 mRNA
CTD
PMID:24136188
NCBI chr 8:46,539,083...46,541,464
Ensembl chr 8:46,539,082...46,541,469
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Apob
apolipoprotein B
decreases expression
EXP
valdecoxib results in decreased expression of APOB mRNA
CTD
PMID:24136188
NCBI chr 6:30,844,386...30,883,983
Ensembl chr 6:30,844,368...30,892,497
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Apoc4
apolipoprotein C4
decreases expression
EXP
valdecoxib results in decreased expression of APOC4 mRNA
CTD
PMID:24136188
NCBI chr 1:79,335,745...79,339,942
Ensembl chr 1:79,335,745...79,339,981
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App
amyloid beta precursor protein
increases expression
EXP
valdecoxib results in increased expression of APP mRNA
CTD
PMID:24136188
NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561
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Aqp9
aquaporin 9
decreases expression
EXP
valdecoxib results in decreased expression of AQP9 mRNA
CTD
PMID:24136188
NCBI chr 8:71,797,231...71,837,485
Ensembl chr 8:71,797,234...71,837,395
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Arhgap8
Rho GTPase activating protein 8
increases expression
EXP
valdecoxib results in increased expression of ARHGAP8 mRNA
CTD
PMID:24136188
NCBI chr 7:115,842,223...115,902,094
Ensembl chr 7:115,850,654...115,902,093
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Arhgef19
Rho guanine nucleotide exchange factor 19
decreases expression
EXP
valdecoxib results in decreased expression of ARHGEF19 mRNA
CTD
PMID:24136188
NCBI chr 5:153,536,038...153,554,203
Ensembl chr 5:153,536,013...153,554,203
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Arl6ip1
ARL6 interacting reticulophagy regulator 1
decreases expression
EXP
valdecoxib results in decreased expression of ARL6IP1 mRNA
CTD
PMID:24136188
NCBI chr 1:172,430,475...172,439,990
Ensembl chr 1:172,430,489...172,439,994
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Arnt
aryl hydrocarbon receptor nuclear translocator
decreases expression
EXP
valdecoxib results in decreased expression of ARNT mRNA
CTD
PMID:24136188
NCBI chr 2:182,997,731...183,056,584
Ensembl chr 2:182,997,736...183,056,580
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Arpp19
cAMP-regulated phosphoprotein 19
increases expression
EXP
valdecoxib results in increased expression of ARPP19 mRNA
CTD
PMID:24136188
NCBI chr 8:75,779,640...75,802,474
Ensembl chr 8:75,779,523...75,802,452 Ensembl chr 8:75,779,523...75,802,452
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Asb1
ankyrin repeat and SOCS box-containing 1
decreases expression
EXP
valdecoxib results in decreased expression of ASB1 mRNA
CTD
PMID:24136188
NCBI chr 9:92,120,332...92,140,790
Ensembl chr 9:92,120,306...92,136,376
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Asnsd1
asparagine synthetase domain containing 1
increases expression
EXP
valdecoxib results in increased expression of ASNSD1 mRNA
CTD
PMID:24136188
NCBI chr 9:48,126,808...48,139,073
Ensembl chr 9:48,126,808...48,139,073
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Ass1
argininosuccinate synthase 1
decreases expression
EXP
valdecoxib results in decreased expression of ASS1 mRNA
CTD
PMID:24136188
NCBI chr 3:14,747,355...14,796,909
Ensembl chr 3:14,747,368...14,796,903
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Atg4d
autophagy related 4D, cysteine peptidase
increases expression
EXP
valdecoxib results in increased expression of ATG4D mRNA
CTD
PMID:24136188
NCBI chr 8:19,807,733...19,817,321
Ensembl chr 8:19,807,766...19,817,321
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Atic
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
increases expression
EXP
valdecoxib results in increased expression of ATIC mRNA
CTD
PMID:24136188
NCBI chr 9:73,164,846...73,184,897
Ensembl chr 9:73,164,846...73,184,889
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Atp1a1
ATPase Na+/K+ transporting subunit alpha 1
decreases expression
EXP
valdecoxib results in decreased expression of ATP1A1 mRNA
CTD
PMID:24136188
NCBI chr 2:189,020,722...189,048,826
Ensembl chr 2:189,020,722...189,048,837
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Atp2b2
ATPase plasma membrane Ca2+ transporting 2
decreases expression
EXP
valdecoxib results in decreased expression of ATP2B2 mRNA
CTD
PMID:24136188
NCBI chr 4:146,894,602...147,208,060
Ensembl chr 4:146,896,332...147,140,665
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Atp6v1g1
ATPase H+ transporting V1 subunit G1
increases expression
EXP
valdecoxib results in increased expression of ATP6V1G1 mRNA
CTD
PMID:24136188
NCBI chr 5:76,961,462...76,967,642
Ensembl chr 5:76,961,499...76,969,463
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Atrn
attractin
decreases expression
EXP
valdecoxib results in decreased expression of ATRN mRNA
CTD
PMID:24136188
NCBI chr 3:118,110,320...118,244,326
Ensembl chr 3:118,110,229...118,244,322
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Aup1
AUP1, lipid droplet regulating VLDL assembly factor
increases expression
EXP
valdecoxib results in increased expression of AUP1 mRNA
CTD
PMID:24136188
NCBI chr 4:115,560,274...115,563,346
Ensembl chr 4:115,560,261...115,563,346
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Avpr1a
arginine vasopressin receptor 1A
decreases expression
EXP
valdecoxib results in decreased expression of AVPR1A mRNA
CTD
PMID:24136188
NCBI chr 7:58,114,306...58,118,230
Ensembl chr 7:58,114,284...58,122,215
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Baz1a
bromodomain adjacent to zinc finger domain, 1A
increases expression
EXP
valdecoxib results in increased expression of BAZ1A mRNA
CTD
PMID:24136188
NCBI chr 6:72,389,701...72,512,516
Ensembl chr 6:72,389,703...72,512,459
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Bbc3
Bcl-2 binding component 3
increases expression
EXP
valdecoxib results in increased expression of BBC3 mRNA
CTD
PMID:24136188
NCBI chr 1:77,013,281...77,022,509
Ensembl chr 1:77,014,543...77,022,509
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Bbox1
gamma-butyrobetaine hydroxylase 1
decreases expression
EXP
valdecoxib results in decreased expression of BBOX1 mRNA
CTD
PMID:24136188
NCBI chr 3:96,822,654...96,871,786
Ensembl chr 3:96,822,655...96,871,458
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Bcar3
BCAR3 adaptor protein, NSP family member
increases expression
EXP
valdecoxib results in increased expression of BCAR3 mRNA
CTD
PMID:24136188
NCBI chr 2:210,525,260...210,638,674
Ensembl chr 2:210,525,260...210,638,798
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Bcl6b
BCL6B, transcription repressor
decreases expression
EXP
valdecoxib results in decreased expression of BCL6B mRNA
CTD
PMID:24136188
NCBI chr10:54,940,908...54,947,022
Ensembl chr10:54,940,909...54,945,974
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Bhmt
betaine-homocysteine S-methyltransferase
decreases expression
EXP
valdecoxib results in decreased expression of BHMT mRNA
CTD
PMID:24136188
NCBI chr 2:24,859,871...24,879,449
Ensembl chr 2:24,859,873...24,879,742
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Blvrb
biliverdin reductase B
increases expression
EXP
valdecoxib results in increased expression of BLVRB mRNA
CTD
PMID:24136188
NCBI chr 1:82,738,646...82,756,312
Ensembl chr 1:82,738,695...82,770,375
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Bmf
Bcl2 modifying factor
decreases expression
EXP
valdecoxib results in decreased expression of BMF mRNA
CTD
PMID:24136188
NCBI chr 3:105,499,534...105,520,159
Ensembl chr 3:105,499,538...105,520,145
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Bmp1
bone morphogenetic protein 1
decreases expression
EXP
valdecoxib results in decreased expression of BMP1 mRNA
CTD
PMID:24136188
NCBI chr15:45,551,603...45,595,862
Ensembl chr15:45,551,603...45,595,776
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Bnip3
BCL2 interacting protein 3
increases expression
EXP
valdecoxib results in increased expression of BNIP3 mRNA
CTD
PMID:24136188
NCBI chr 1:193,708,164...193,725,348
Ensembl chr 1:193,708,167...193,725,359
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Bola1
bolA family member 1
increases expression
EXP
valdecoxib results in increased expression of BOLA1 mRNA
CTD
PMID:24136188
NCBI chr 2:183,758,515...183,771,445
Ensembl chr 2:183,758,441...183,781,576
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Bpgm
bisphosphoglycerate mutase
decreases expression
EXP
valdecoxib results in decreased expression of BPGM mRNA
CTD
PMID:24136188
NCBI chr 4:63,139,730...63,168,581
Ensembl chr 4:63,140,018...63,168,581
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C1qtnf1
C1q and TNF related 1
increases expression
EXP
valdecoxib results in increased expression of C1QTNF1 mRNA
CTD
PMID:24136188
NCBI chr10:103,660,319...103,681,662
Ensembl chr10:103,660,327...103,681,660
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C20h6orf89
similar to human chromosome 6 open reading frame 89
increases expression
EXP
valdecoxib results in increased expression of C20H6ORF89 mRNA
CTD
PMID:24136188
NCBI chr20:7,322,483...7,362,054
Ensembl chr20:7,322,442...7,357,612
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C8h15orf39
similar to human chromosome 15 open reading frame 39
increases expression
EXP
valdecoxib results in increased expression of C8H15ORF39 mRNA
CTD
PMID:24136188
NCBI chr 8:57,646,324...57,655,896
Ensembl chr 8:57,645,756...57,655,941
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Cacybp
calcyclin binding protein
increases expression
EXP
valdecoxib results in increased expression of CACYBP mRNA
CTD
PMID:24136188
NCBI chr13:72,437,485...72,447,810
Ensembl chr13:72,437,490...72,450,177
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Cadm1
cell adhesion molecule 1
increases expression
EXP
valdecoxib results in increased expression of CADM1 mRNA
CTD
PMID:24136188
NCBI chr 8:47,847,836...48,178,703
Ensembl chr 8:47,847,325...48,182,833
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Car14
carbonic anhydrase 14
decreases expression
EXP
valdecoxib results in decreased expression of CAR14 mRNA
CTD
PMID:24136188
NCBI chr 2:183,442,263...183,449,231
Ensembl chr 2:183,441,667...183,449,693
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Car2
carbonic anhydrase 2
multiple interactions
ISO
valdecoxib binds to and results in decreased activity of CA2 protein
CTD
PMID:17826101
NCBI chr 2:86,741,625...86,756,766
Ensembl chr 2:86,741,626...86,756,818
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Car3
carbonic anhydrase 3
multiple interactions decreases expression
ISO EXP
valdecoxib binds to and results in decreased activity of CA3 protein valdecoxib results in decreased expression of CAR3 mRNA
CTD
PMID:17826101 PMID:24136188
NCBI chr 2:86,770,418...86,780,011
Ensembl chr 2:86,770,420...86,784,280
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Car5a
carbonic anhydrase 5A
decreases expression
EXP
valdecoxib results in decreased expression of CAR5A mRNA
CTD
PMID:24136188
NCBI chr19:49,973,092...50,002,948
Ensembl chr19:49,973,107...50,002,906
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Car8
carbonic anhydrase 8
increases expression
EXP
valdecoxib results in increased expression of CAR8 mRNA
CTD
PMID:24136188
NCBI chr 5:21,302,940...21,402,395
Ensembl chr 5:21,305,383...21,402,374
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Cav2
caveolin 2
increases expression
EXP
valdecoxib results in increased expression of CAV2 mRNA
CTD
PMID:24136188
NCBI chr 4:45,616,766...45,624,144
Ensembl chr 4:45,616,712...45,624,244
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Cavin3
caveolae associated protein 3
increases expression
EXP
valdecoxib results in increased expression of CAVIN3 mRNA
CTD
PMID:24136188
NCBI chr 1:159,826,549...159,828,138
Ensembl chr 1:159,826,549...159,828,161
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Cbr1
carbonyl reductase 1
increases expression
EXP
valdecoxib results in increased expression of CBR1 mRNA
CTD
PMID:24136188
NCBI chr11:32,860,571...32,862,981
Ensembl chr11:32,908,950...32,911,393 Ensembl chr11:32,908,950...32,911,393 Ensembl chr11:32,908,950...32,911,393
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Cby1
chibby 1, beta catenin antagonist
decreases expression
EXP
valdecoxib results in decreased expression of CBY1 mRNA
CTD
PMID:24136188
NCBI chr 7:111,216,835...111,223,305
G
Ccdc28a
coiled-coil domain containing 28A
increases expression
EXP
valdecoxib results in increased expression of CCDC28A mRNA
CTD
PMID:24136188
NCBI chr 1:12,857,668...12,872,944
Ensembl chr 1:12,857,666...12,873,003
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Ccdc47
coiled-coil domain containing 47
increases expression
EXP
valdecoxib results in increased expression of CCDC47 mRNA
CTD
PMID:24136188
NCBI chr10:91,130,303...91,148,829
Ensembl chr10:91,130,303...91,148,881
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Cct2
chaperonin containing TCP1 subunit 2
increases expression
EXP
valdecoxib results in increased expression of CCT2 mRNA
CTD
PMID:24136188
NCBI chr 7:52,692,725...52,705,478
Ensembl chr 7:52,692,725...52,706,944
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Cct3
chaperonin containing TCP1 subunit 3
increases expression
EXP
valdecoxib results in increased expression of CCT3 mRNA
CTD
PMID:24136188
NCBI chr 2:173,765,701...173,790,353
Ensembl chr 2:173,765,698...173,790,757
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Cct4
chaperonin containing TCP1 subunit 4
increases expression
EXP
valdecoxib results in increased expression of CCT4 mRNA
CTD
PMID:24136188
NCBI chr14:96,991,853...97,004,732
Ensembl chr14:96,991,859...97,005,267
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Cct5
chaperonin containing TCP1 subunit 5
increases expression
EXP
valdecoxib results in increased expression of CCT5 mRNA
CTD
PMID:24136188
NCBI chr 2:82,591,750...82,602,903
Ensembl chr 2:82,590,630...82,602,930
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Cct6a
chaperonin containing TCP1 subunit 6A
increases expression
EXP
valdecoxib results in increased expression of CCT6A mRNA
CTD
PMID:24136188
NCBI chr12:26,872,736...26,883,125
Ensembl chr12:26,872,574...26,883,337
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Cct7
chaperonin containing TCP1 subunit 7
increases expression
EXP
valdecoxib results in increased expression of CCT7 mRNA
CTD
PMID:24136188
NCBI chr 4:117,989,232...118,006,478
Ensembl chr 4:117,989,232...118,006,580
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Cct8
chaperonin containing TCP1 subunit 8
increases expression
EXP
valdecoxib results in increased expression of CCT8 mRNA
CTD
PMID:24136188
NCBI chr11:26,710,370...26,722,079
Ensembl chr11:26,710,370...26,722,079
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Cd1d1
CD1d1 molecule
decreases expression
EXP
valdecoxib results in decreased expression of CD1D1 mRNA
CTD
PMID:24136188
NCBI chr 2:172,423,582...172,427,089
Ensembl chr 2:172,423,582...172,427,089
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Cd81
Cd81 molecule
decreases expression
EXP
valdecoxib results in decreased expression of CD81 mRNA
CTD
PMID:24136188
NCBI chr 1:198,235,861...198,251,660
Ensembl chr 1:198,241,484...198,251,660
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Cd99l2
CD99 molecule-like 2
decreases expression
EXP
valdecoxib results in decreased expression of CD99L2 mRNA
CTD
PMID:24136188
G
Cdip1
cell death-inducing p53 target 1
decreases expression
EXP
valdecoxib results in decreased expression of CDIP1 mRNA
CTD
PMID:24136188
NCBI chr10:10,773,538...10,796,979
Ensembl chr10:10,774,705...10,796,980
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Cdkn2aip
CDKN2A interacting protein
increases expression
EXP
valdecoxib results in increased expression of CDKN2AIP mRNA
CTD
PMID:24136188
NCBI chr16:44,536,147...44,546,216
Ensembl chr16:44,536,234...44,540,033
G
Cdkn3
cyclin-dependent kinase inhibitor 3
decreases expression
EXP
valdecoxib results in decreased expression of CDKN3 mRNA
CTD
PMID:24136188
NCBI chr15:20,022,522...20,033,948
Ensembl chr15:20,022,664...20,033,945
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Cdo1
cysteine dioxygenase type 1
decreases expression
EXP
valdecoxib results in decreased expression of CDO1 mRNA
CTD
PMID:24136188
NCBI chr18:39,432,473...39,447,253
Ensembl chr18:39,432,474...39,447,296
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Cebpa
CCAAT/enhancer binding protein alpha
decreases expression
EXP
valdecoxib results in decreased expression of CEBPA mRNA
CTD
PMID:24136188
NCBI chr 1:87,759,631...87,762,303
Ensembl chr 1:87,759,433...87,762,412
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Cela1
chymotrypsin like elastase 1
decreases expression
EXP
valdecoxib results in decreased expression of CELA1 mRNA
CTD
PMID:24136188
NCBI chr 7:131,773,161...131,786,300
Ensembl chr 7:131,742,002...131,786,285
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Cep83
centrosomal protein 83
increases expression
EXP
valdecoxib results in increased expression of CEP83 mRNA
CTD
PMID:24136188
NCBI chr 7:29,280,358...29,389,574
Ensembl chr 7:29,280,419...29,389,574
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Ces2h
carboxylesterase 2H
increases expression
EXP
valdecoxib results in increased expression of CES2 mRNA
CTD
PMID:24136188
NCBI chr19:32,974,242...32,988,842
Ensembl chr19:32,974,242...32,988,830
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Chchd6
coiled-coil-helix-coiled-coil-helix domain containing 6
increases expression
EXP
valdecoxib results in increased expression of CHCHD6 mRNA
CTD
PMID:24136188
NCBI chr 4:121,803,501...122,024,209
Ensembl chr 4:121,792,717...122,024,216
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Chdh
choline dehydrogenase
decreases expression
EXP
valdecoxib results in decreased expression of CHDH mRNA
CTD
PMID:24136188
NCBI chr16:5,194,269...5,225,541
Ensembl chr16:5,194,269...5,225,537
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Chmp4c
charged multivesicular body protein 4C
increases expression
EXP
valdecoxib results in increased expression of CHMP4C mRNA
CTD
PMID:24136188
NCBI chr 2:91,391,729...91,428,652
Ensembl chr 2:91,388,530...91,428,668
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Chordc1
cysteine and histidine rich domain containing 1
increases expression
EXP
valdecoxib results in increased expression of CHORDC1 mRNA
CTD
PMID:24136188
NCBI chr 8:15,374,356...15,398,436
Ensembl chr 8:15,374,471...15,399,162
G
Chtf8
chromosome transmission fidelity factor 8
increases expression
EXP
valdecoxib results in increased expression of CHTF8 mRNA
CTD
PMID:24136188
NCBI chr19:34,782,005...34,792,306
Ensembl chr19:34,781,856...34,792,578
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Ciao2b
cytosolic iron-sulfur assembly component 2B
increases expression
EXP
valdecoxib results in increased expression of CIAO2B mRNA
CTD
PMID:24136188
NCBI chr19:344,194...346,068
Ensembl chr19:344,203...346,068
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Cidec
cell death-inducing DFFA-like effector c
decreases expression
EXP
valdecoxib results in decreased expression of CIDEC mRNA
CTD
PMID:24136188
NCBI chr 4:146,569,288...146,582,173
Ensembl chr 4:146,569,289...146,582,173
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Cited2
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
decreases expression
EXP
valdecoxib results in decreased expression of CITED2 mRNA
CTD
PMID:24136188
NCBI chr 1:12,312,426...12,314,869
Ensembl chr 1:12,312,160...12,314,897
G
Cldn2
claudin 2
decreases expression
EXP
valdecoxib results in decreased expression of CLDN2 mRNA
CTD
PMID:24136188
NCBI chr X:103,459,870...103,473,794
Ensembl chr X:103,459,780...103,474,838
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Clec14a
C-type lectin domain containing 14A
increases expression
EXP
valdecoxib results in increased expression of CLEC14A mRNA
CTD
PMID:24136188
NCBI chr 6:75,881,470...75,884,612
Ensembl chr 6:75,881,473...75,884,612
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Cltb
clathrin, light chain B
increases expression
EXP
valdecoxib results in increased expression of CLTB mRNA
CTD
PMID:24136188
NCBI chr17:10,001,512...10,019,201
Ensembl chr17:10,001,513...10,019,169
G
Cmas
cytidine monophosphate N-acetylneuraminic acid synthetase
increases expression
EXP
valdecoxib results in increased expression of CMAS mRNA
CTD
PMID:24136188
NCBI chr 4:175,718,808...175,737,128
Ensembl chr 4:175,718,808...175,737,125
G
Cmtm6
CKLF-like MARVEL transmembrane domain containing 6
decreases expression
EXP
valdecoxib results in decreased expression of CMTM6 mRNA
CTD
PMID:24136188
NCBI chr 8:114,422,934...114,441,034
Ensembl chr 8:114,422,921...114,441,033
G
Cmya5
cardiomyopathy associated 5
decreases expression
EXP
valdecoxib results in decreased expression of CMYA5 mRNA
CTD
PMID:24136188
NCBI chr 2:24,279,520...24,378,253
Ensembl chr 2:24,279,528...24,378,364
G
Cndp2
carnosine dipeptidase 2
increases expression
EXP
valdecoxib results in increased expression of CNDP2 mRNA
CTD
PMID:24136188
NCBI chr18:78,039,924...78,057,030
Ensembl chr18:78,039,932...78,056,922
G
Cops5
COP9 signalosome subunit 5
increases expression
EXP
valdecoxib results in increased expression of COPS5 mRNA
CTD
PMID:24136188
NCBI chr 5:9,192,233...9,210,498
Ensembl chr 5:9,192,100...9,210,731
G
Coq10a
coenzyme Q10A
decreases expression
EXP
valdecoxib results in decreased expression of COQ10A mRNA
CTD
PMID:24136188
NCBI chr 7:792,089...798,392
Ensembl chr 7:792,089...800,161
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Cox19
cytochrome c oxidase assembly factor COX19
increases expression
EXP
valdecoxib results in increased expression of COX19 mRNA
CTD
PMID:24136188
NCBI chr12:15,303,535...15,313,014
Ensembl chr12:15,303,551...15,313,014
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Cp
ceruloplasmin
increases expression
EXP
valdecoxib results in increased expression of CP mRNA
CTD
PMID:24136188
NCBI chr 2:102,439,433...102,498,075
Ensembl chr 2:102,439,624...102,498,075
G
Cps1
carbamoyl-phosphate synthase 1
decreases expression
EXP
valdecoxib results in decreased expression of CPS1 mRNA
CTD
PMID:24136188
NCBI chr 9:68,614,153...68,737,037
Ensembl chr 9:68,614,153...68,737,033
G
Crat
carnitine O-acetyltransferase
increases expression
EXP
valdecoxib results in increased expression of CRAT mRNA
CTD
PMID:24136188
NCBI chr 3:13,675,684...13,689,282
Ensembl chr 3:13,675,684...13,689,255
G
Creb3
cAMP responsive element binding protein 3
increases expression
EXP
valdecoxib results in increased expression of CREB3 mRNA
CTD
PMID:24136188
NCBI chr 5:57,817,865...57,823,233
Ensembl chr 5:57,817,832...57,824,390
G
Creg1
cellular repressor of E1A-stimulated genes 1
increases expression
EXP
valdecoxib results in increased expression of CREG1 mRNA
CTD
PMID:24136188
NCBI chr13:78,019,814...78,032,310
Ensembl chr13:78,019,843...78,032,308
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Crem
cAMP responsive element modulator
decreases expression
EXP
valdecoxib results in decreased expression of CREM mRNA
CTD
PMID:24136188
NCBI chr17:54,238,889...54,305,989
Ensembl chr17:54,239,030...54,305,989
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Crim1
cysteine rich transmembrane BMP regulator 1
increases expression
EXP
valdecoxib results in increased expression of CRIM1 mRNA
CTD
PMID:24136188
NCBI chr 6:16,695,864...16,870,264
Ensembl chr 6:16,697,829...16,870,259
G
Cryl1
crystallin, lambda 1
increases expression
EXP
valdecoxib results in increased expression of CRYL1 mRNA
CTD
PMID:24136188
NCBI chr15:31,427,011...31,545,997
Ensembl chr15:31,427,054...31,545,997
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Cryz
crystallin zeta
decreases expression
EXP
valdecoxib results in decreased expression of CRYZ mRNA
CTD
PMID:24136188
NCBI chr 2:243,552,037...243,580,369
Ensembl chr 2:243,552,119...243,579,758
G
Csad
cysteine sulfinic acid decarboxylase
decreases expression
EXP
valdecoxib results in decreased expression of CSAD mRNA
CTD
PMID:24136188
NCBI chr 7:133,308,571...133,337,914
Ensembl chr 7:133,308,574...133,337,615
G
Csnk1d
casein kinase 1, delta
decreases expression
EXP
valdecoxib results in decreased expression of CSNK1D mRNA
CTD
PMID:24136188
NCBI chr10:106,221,992...106,256,620
Ensembl chr10:106,221,992...106,256,614
G
Csrp1
cysteine and glycine-rich protein 1
decreases expression
EXP
valdecoxib results in decreased expression of CSRP1 mRNA
CTD
PMID:24136188
NCBI chr13:47,158,171...47,179,388
Ensembl chr13:47,167,789...47,179,384
G
Ctf1
cardiotrophin 1
increases expression
EXP
valdecoxib results in increased expression of CTF1 mRNA
CTD
PMID:24136188
NCBI chr 1:182,328,035...182,336,346
Ensembl chr 1:182,328,090...182,333,335
G
Cth
cystathionine gamma-lyase
decreases expression
EXP
valdecoxib results in decreased expression of CTH mRNA
CTD
PMID:24136188
NCBI chr 2:246,975,888...247,002,234
Ensembl chr 2:246,975,894...247,002,234
G
Ctsd
cathepsin D
increases expression
EXP
valdecoxib results in increased expression of CTSD mRNA
CTD
PMID:24136188
NCBI chr 1:197,527,467...197,539,343
Ensembl chr 1:197,527,467...197,539,488
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Ctsl
cathepsin L
increases expression
EXP
valdecoxib results in increased expression of CTSL mRNA
CTD
PMID:24136188
NCBI chr17:764,370...770,533
Ensembl chr17:764,309...770,548
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Ctss
cathepsin S
increases expression
EXP
valdecoxib results in increased expression of CTSS mRNA
CTD
PMID:24136188
NCBI chr 2:183,086,437...183,114,483
Ensembl chr 2:183,086,437...183,114,483
G
Cxcl1
C-X-C motif chemokine ligand 1
increases expression
EXP
valdecoxib results in increased expression of CXCL1 mRNA
CTD
PMID:24136188
NCBI chr14:17,193,364...17,195,143
Ensembl chr14:17,193,365...17,195,215
G
Cyb5a
cytochrome b5 type A
increases expression
EXP
valdecoxib results in increased expression of CYB5A mRNA
CTD
PMID:24136188
NCBI chr18:78,213,067...78,245,677
Ensembl chr18:78,202,342...78,258,535 Ensembl chr18:78,202,342...78,258,535
G
Cyp17a1
cytochrome P450, family 17, subfamily a, polypeptide 1
decreases expression
EXP
valdecoxib results in decreased expression of CYP17A1 mRNA
CTD
PMID:24136188
NCBI chr 1:245,535,462...245,543,148
Ensembl chr 1:245,535,462...245,541,573
G
Cyp1a1
cytochrome P450, family 1, subfamily a, polypeptide 1
increases expression decreases activity
EXP ISO
valdecoxib results in increased expression of CYP1A1 mRNA valdecoxib results in decreased activity of CYP1A1 protein
CTD
PMID:24136188 PMID:33814510
NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
G
Cyp1a2
cytochrome P450, family 1, subfamily a, polypeptide 2
increases expression
EXP
valdecoxib results in increased expression of CYP1A2 mRNA
CTD
PMID:24136188
NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
G
Cyp1b1
cytochrome P450, family 1, subfamily b, polypeptide 1
decreases activity
ISO
valdecoxib results in decreased activity of CYP1B1 protein
CTD
PMID:33814510
NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917
G
Cyp2b1
cytochrome P450, family 2, subfamily b, polypeptide 1
increases expression
EXP
valdecoxib results in increased expression of CYP2B1 mRNA
CTD
PMID:24136188
NCBI chr 1:81,518,387...81,544,999
Ensembl chr 1:81,518,408...81,542,052
G
Cyp2c6
cytochrome P450, family 2, subfamily C, polypeptide 6
increases expression
EXP
valdecoxib results in increased expression of CYP2C6 mRNA
CTD
PMID:24136188
NCBI chr 1:237,938,521...237,976,238
Ensembl chr 1:237,693,094...238,057,596
G
Cyp2d4
cytochrome P450, family 2, subfamily d, polypeptide 4
decreases expression
EXP
valdecoxib results in decreased expression of CYP2D4 mRNA
CTD
PMID:24136188
NCBI chr 7:113,882,584...113,891,754
Ensembl chr 7:113,881,618...113,891,759
G
Cyp2t1
cytochrome P450, family 2, subfamily t, polypeptide 1
decreases expression
EXP
valdecoxib results in decreased expression of CYP2T1 mRNA
CTD
PMID:24136188
NCBI chr 1:82,446,321...82,451,564
Ensembl chr 1:82,446,921...82,451,563
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Cyp3a18
cytochrome P450, family 3, subfamily a, polypeptide 18
increases expression
EXP
valdecoxib results in increased expression of CYP3A18 mRNA
CTD
PMID:24136188
NCBI chr12:8,880,509...8,930,382
Ensembl chr12:8,880,528...8,930,381
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Cyp3a23-3a1
cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1
increases expression
EXP
valdecoxib results in increased expression of CYP3A23-3A1 mRNA
CTD
PMID:24136188
NCBI chr12:9,256,159...9,285,020
Ensembl chr12:9,254,475...9,285,030 Ensembl chr12:9,254,475...9,285,030
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Cyp3a9
cytochrome P450, family 3, subfamily a, polypeptide 9
increases expression
EXP
valdecoxib results in increased expression of CYP3A9 mRNA
CTD
PMID:24136188
NCBI chr12:16,806,222...16,846,428
Ensembl chr12:16,806,207...16,846,422
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Cyp4a3
cytochrome P450, family 4, subfamily a, polypeptide 3
increases expression
EXP
valdecoxib results in increased expression of CYP4A3 mRNA
CTD
PMID:24136188
NCBI chr 5:129,097,571...129,115,488
Ensembl chr 5:129,097,926...129,115,463
G
Cyp51
cytochrome P450, family 51
increases expression
EXP
valdecoxib results in increased expression of CYP51 mRNA
CTD
PMID:24136188
NCBI chr 4:30,036,956...30,055,410
Ensembl chr 4:30,036,865...30,055,410 Ensembl chr 6:30,036,865...30,055,410
G
Cyp7a1
cytochrome P450 family 7 subfamily A member 1
decreases expression
EXP
valdecoxib results in decreased expression of CYP7A1 mRNA
CTD
PMID:24136188
NCBI chr 5:19,376,979...19,386,676
Ensembl chr 5:19,376,974...19,386,688
G
Cyp8b1
cytochrome P450 family 8 subfamily B member 1
decreases expression
EXP
valdecoxib results in decreased expression of CYP8B1 mRNA
CTD
PMID:24136188
NCBI chr 8:121,578,123...121,580,093
Ensembl chr 8:121,557,062...121,580,166
G
Daam1
dishevelled associated activator of morphogenesis 1
decreases expression
EXP
valdecoxib results in decreased expression of DAAM1 mRNA
CTD
PMID:24136188
NCBI chr 6:90,389,544...90,550,114
Ensembl chr 6:90,389,688...90,550,114
G
Dcaf6
DDB1 and CUL4 associated factor 6
increases expression
EXP
valdecoxib results in increased expression of DCAF6 mRNA
CTD
PMID:24136188
NCBI chr13:77,626,257...77,727,645
Ensembl chr13:77,626,307...77,727,512
G
Ddit4
DNA-damage-inducible transcript 4
decreases expression
EXP
valdecoxib results in decreased expression of DDIT4 mRNA
CTD
PMID:24136188
NCBI chr20:27,891,989...27,894,088
Ensembl chr20:27,891,998...27,894,105
G
Dennd2a
DENN domain containing 2A
increases expression
EXP
valdecoxib results in increased expression of DENND2A mRNA
CTD
PMID:24136188
NCBI chr 4:68,233,016...68,332,235
Ensembl chr 4:68,233,958...68,332,105
G
Dennd4c
DENN domain containing 4C
increases expression
EXP
valdecoxib results in increased expression of DENND4C mRNA
CTD
PMID:24136188
NCBI chr 5:101,272,298...101,369,529
Ensembl chr 5:101,272,005...101,368,118
G
Dexi
Dexi homolog
decreases expression
EXP
valdecoxib results in decreased expression of DEXI mRNA
CTD
PMID:24136188
NCBI chr10:5,126,021...5,138,746
Ensembl chr10:5,137,288...5,138,738
G
Dgat2
diacylglycerol O-acyltransferase 2
decreases expression
EXP
valdecoxib results in decreased expression of DGAT2 mRNA
CTD
PMID:24136188
NCBI chr 1:153,454,078...153,484,432
Ensembl chr 1:153,454,080...153,484,428
G
Dgkd
diacylglycerol kinase, delta
increases expression
EXP
valdecoxib results in increased expression of DGKD mRNA
CTD
PMID:24136188
NCBI chr 9:88,516,686...88,607,349
Ensembl chr 9:88,516,715...88,607,345
G
Dmgdh
dimethylglycine dehydrogenase
decreases expression
EXP
valdecoxib results in decreased expression of DMGDH mRNA
CTD
PMID:24136188
NCBI chr 2:24,912,600...24,987,533
Ensembl chr 2:24,912,578...24,987,528
G
Dpt
dermatopontin
decreases expression
EXP
valdecoxib results in decreased expression of DPT mRNA
CTD
PMID:24136188
NCBI chr13:77,123,224...77,151,646
Ensembl chr13:77,123,115...77,151,639
G
Dpyd
dihydropyrimidine dehydrogenase
decreases expression
EXP
valdecoxib results in decreased expression of DPYD mRNA
CTD
PMID:24136188
NCBI chr 2:206,609,043...207,474,982
Ensembl chr 2:206,609,122...207,474,982
G
Dsc2
desmocollin 2
increases expression
EXP
valdecoxib results in increased expression of DSC2 mRNA
CTD
PMID:24136188
NCBI chr18:11,450,392...11,482,476
Ensembl chr18:11,450,390...11,482,392
G
Dusp1
dual specificity phosphatase 1
decreases expression
EXP
valdecoxib results in decreased expression of DUSP1 mRNA
CTD
PMID:24136188
NCBI chr10:16,680,478...16,683,275
G
Dusp5
dual specificity phosphatase 5
increases expression
EXP
valdecoxib results in increased expression of DUSP5 mRNA
CTD
PMID:24136188
NCBI chr 1:252,538,408...252,555,320
Ensembl chr 1:252,538,449...252,551,818
G
Dynll1
dynein light chain LC8-type 1
increases expression
EXP
valdecoxib results in increased expression of DYNLL1 mRNA
CTD
PMID:24136188
NCBI chr12:41,312,365...41,316,157
Ensembl chr12:41,312,367...41,314,741
G
Ebna1bp2
EBNA1 binding protein 2
increases expression
EXP
valdecoxib results in increased expression of EBNA1BP2 mRNA
CTD
PMID:24136188
NCBI chr 5:132,148,164...132,152,730
Ensembl chr 5:132,148,143...132,153,267
G
Ebpl
EBP like
increases expression
EXP
valdecoxib results in increased expression of EBPL mRNA
CTD
PMID:24136188
NCBI chr15:35,508,074...35,531,472
Ensembl chr15:35,508,074...35,531,472
G
Ech1
enoyl-CoA hydratase 1
increases expression
EXP
valdecoxib results in increased expression of ECH1 mRNA
CTD
PMID:24136188
NCBI chr 1:84,114,494...84,120,788
Ensembl chr 1:84,112,751...84,120,795
G
Eci1
enoyl-CoA delta isomerase 1
increases expression
EXP
valdecoxib results in increased expression of ECI1 mRNA
CTD
PMID:24136188
NCBI chr10:13,456,715...13,470,061
Ensembl chr10:13,456,563...13,470,061
G
Ecpas
Ecm29 proteasome adaptor and scaffold
increases expression
EXP
valdecoxib results in increased expression of ECPAS mRNA
CTD
PMID:24136188
NCBI chr 5:73,601,745...73,714,026
Ensembl chr 5:73,604,533...73,713,860
G
Edem1
ER degradation enhancing alpha-mannosidase like protein 1
decreases expression
EXP
valdecoxib results in decreased expression of EDEM1 mRNA
CTD
PMID:24136188
NCBI chr 4:141,797,631...141,829,717
Ensembl chr 4:141,797,701...141,829,717
G
Efna1
ephrin A1
increases expression
EXP
valdecoxib results in increased expression of EFNA1 mRNA
CTD
PMID:24136188
NCBI chr 2:174,681,676...174,689,061
Ensembl chr 2:174,681,682...174,690,866
G
Egfr
epidermal growth factor receptor
decreases expression
EXP
valdecoxib results in decreased expression of EGFR mRNA
CTD
PMID:24136188
NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382
G
Egr1
early growth response 1
increases expression
EXP
valdecoxib results in increased expression of EGR1 mRNA
CTD
PMID:24136188
NCBI chr18:26,462,967...26,466,766
Ensembl chr18:26,462,981...26,466,766
G
Eif1ax
eukaryotic translation initiation factor 1A, X-linked
increases expression
EXP
valdecoxib results in increased expression of EIF1AX mRNA
CTD
PMID:24136188
NCBI chr X:35,498,698...35,513,402
Ensembl chr X:35,498,517...35,513,335
G
Eif2a
eukaryotic translation initiation factor 2A
increases expression
EXP
valdecoxib results in increased expression of EIF2A mRNA
CTD
PMID:24136188
NCBI chr 2:142,761,303...142,794,767
Ensembl chr 2:142,761,416...142,795,068
G
Eif2ak3
eukaryotic translation initiation factor 2 alpha kinase 3
decreases expression
EXP
valdecoxib results in decreased expression of EIF2AK3 mRNA
CTD
PMID:24136188
NCBI chr 4:102,805,495...102,866,914
Ensembl chr 4:102,805,510...102,866,911
G
Eif3a
eukaryotic translation initiation factor 3, subunit A
decreases expression
EXP
valdecoxib results in decreased expression of EIF3A mRNA
CTD
PMID:24136188
NCBI chr 1:259,902,767...259,932,976
Ensembl chr 1:259,902,680...259,932,976
G
Eif4g1
eukaryotic translation initiation factor 4 gamma 1
increases expression
EXP
valdecoxib results in increased expression of EIF4G1 mRNA
CTD
PMID:24136188
NCBI chr11:80,221,919...80,241,958
Ensembl chr11:80,221,919...80,241,941
G
Eif5
eukaryotic translation initiation factor 5
increases expression
EXP
valdecoxib results in increased expression of EIF5 mRNA
CTD
PMID:24136188
NCBI chr 6:130,589,162...130,597,656
Ensembl chr 6:130,589,143...130,597,656
G
Elovl5
ELOVL fatty acid elongase 5
decreases expression
EXP
valdecoxib results in decreased expression of ELOVL5 mRNA
CTD
PMID:24136188
NCBI chr 8:78,790,846...78,857,307
Ensembl chr 8:78,790,846...78,857,284
G
Elovl6
ELOVL fatty acid elongase 6
decreases expression
EXP
valdecoxib results in decreased expression of ELOVL6 mRNA
CTD
PMID:24136188
NCBI chr 2:218,063,682...218,174,767
Ensembl chr 2:218,063,804...218,171,186
G
Enpep
glutamyl aminopeptidase
decreases expression
EXP
valdecoxib results in decreased expression of ENPEP mRNA
CTD
PMID:24136188
NCBI chr 2:217,781,985...217,851,947
Ensembl chr 2:217,782,005...217,851,947
G
Epb41l5
erythrocyte membrane protein band 4.1 like 5
increases expression
EXP
valdecoxib results in increased expression of EPB41L5 mRNA
CTD
PMID:24136188
NCBI chr13:30,670,792...30,770,213
Ensembl chr13:30,669,764...30,768,360
G
Ephx1
epoxide hydrolase 1
increases expression
EXP
valdecoxib results in increased expression of EPHX1 mRNA
CTD
PMID:24136188
NCBI chr13:92,714,315...92,744,105
Ensembl chr13:92,714,315...92,790,235
G
Errfi1
ERBB receptor feedback inhibitor 1
decreases expression
EXP
valdecoxib results in decreased expression of ERRFI1 mRNA
CTD
PMID:24136188
NCBI chr 5:161,323,981...161,337,289
Ensembl chr 5:161,323,998...161,337,282
G
Ethe1
ETHE1, persulfide dioxygenase
decreases expression
EXP
valdecoxib results in decreased expression of ETHE1 mRNA
CTD
PMID:24136188
NCBI chr 1:80,184,037...80,199,092
Ensembl chr 1:80,183,894...80,199,052
G
Etv3
ETS variant transcription factor 3
increases expression
EXP
valdecoxib results in increased expression of ETV3 mRNA
CTD
PMID:24136188
NCBI chr 2:172,965,461...172,980,320
Ensembl chr 2:172,965,588...172,980,314
G
Exo5
exonuclease 5
increases expression
EXP
valdecoxib results in increased expression of EXO5 mRNA
CTD
PMID:24136188
NCBI chr 5:134,494,440...134,497,757
Ensembl chr 5:134,493,829...134,497,772
G
Extl1
exostosin-like glycosyltransferase 1
decreases expression
EXP
valdecoxib results in decreased expression of EXTL1 mRNA
CTD
PMID:24136188
NCBI chr 5:146,573,911...146,589,115
Ensembl chr 5:146,573,912...146,589,115
G
Faah
fatty acid amide hydrolase
decreases expression
EXP
valdecoxib results in decreased expression of FAAH mRNA
CTD
PMID:24136188
NCBI chr 5:129,479,774...129,499,018
Ensembl chr 5:129,479,824...129,498,677
G
Fabp5
fatty acid binding protein 5
decreases expression
EXP
valdecoxib results in decreased expression of FABP5 mRNA
CTD
PMID:24136188
NCBI chr 2:91,765,056...91,768,716
Ensembl chr 2:91,765,056...91,853,773
G
Fads2
fatty acid desaturase 2
decreases expression
EXP
valdecoxib results in decreased expression of FADS2 mRNA
CTD
PMID:24136188
NCBI chr 1:206,707,384...206,747,333
Ensembl chr 1:206,708,783...206,748,789
G
Fam117b
family with sequence similarity 117, member B
decreases expression
EXP
valdecoxib results in decreased expression of FAM117B mRNA
CTD
PMID:24136188
NCBI chr 9:61,340,284...61,418,531
Ensembl chr 9:61,340,249...61,408,483
G
Fam136a
family with sequence similarity 136, member A
increases expression
EXP
valdecoxib results in increased expression of FAM136A mRNA
CTD
PMID:24136188
NCBI chr 4:118,805,129...118,811,046
Ensembl chr 4:118,805,127...118,811,047
G
Fam210b
family with sequence similarity 210, member B
decreases expression
EXP
valdecoxib results in decreased expression of FAM210B mRNA
CTD
PMID:24136188
NCBI chr 3:161,118,228...161,128,400
Ensembl chr 3:161,118,239...161,128,397
G
Fam3a
FAM3 metabolism regulating signaling molecule A
increases expression
EXP
valdecoxib results in increased expression of FAM3A mRNA
CTD
PMID:24136188
NCBI chr X:152,166,716...152,175,327
Ensembl chr X:152,165,535...152,175,362
G
Fasn
fatty acid synthase
decreases expression
EXP
valdecoxib results in decreased expression of FASN mRNA
CTD
PMID:24136188
NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261
G
Fastkd2
FAST kinase domains 2
increases expression
EXP
valdecoxib results in increased expression of FASTKD2 mRNA
CTD
PMID:24136188
NCBI chr 9:65,166,148...65,188,184
Ensembl chr 9:65,168,228...65,188,174
G
Fbl
fibrillarin
increases expression
EXP
valdecoxib results in increased expression of FBL mRNA
CTD
PMID:24136188
NCBI chr 1:83,469,832...83,478,932
Ensembl chr 1:83,469,832...83,478,932
G
Fdps
farnesyl diphosphate synthase
increases expression
EXP
valdecoxib results in increased expression of FDPS mRNA
CTD
PMID:24136188
NCBI chr 2:174,497,402...174,507,031
Ensembl chr 2:174,486,665...174,507,776
G
Fgf2
fibroblast growth factor 2
multiple interactions affects secretion
ISO
valdecoxib affects the reaction [Lipopolysaccharides results in increased secretion of FGF2 protein] valdecoxib affects the secretion of FGF2 protein
CTD
PMID:24431307
NCBI chr 2:120,236,328...120,290,673
Ensembl chr 2:120,236,328...120,291,221
G
Fggy
FGGY carbohydrate kinase domain containing
decreases expression
EXP
valdecoxib results in decreased expression of FGGY mRNA
CTD
PMID:24136188
NCBI chr 5:110,398,866...110,786,019
Ensembl chr 5:110,398,863...110,786,017
G
Fkbp3
FKBP prolyl isomerase 3
increases expression
EXP
valdecoxib results in increased expression of FKBP3 mRNA
CTD
PMID:24136188
NCBI chr 6:83,113,885...83,125,500
Ensembl chr 6:83,113,786...83,127,011
G
Fkbp5
FKBP prolyl isomerase 5
increases expression
EXP
valdecoxib results in increased expression of FKBP5 mRNA
CTD
PMID:24136188
NCBI chr20:6,457,207...6,575,404
Ensembl chr20:6,457,216...6,541,674
G
Flcn
folliculin
increases expression
EXP
valdecoxib results in increased expression of FLCN mRNA
CTD
PMID:24136188
NCBI chr10:44,588,621...44,607,808
Ensembl chr10:44,588,624...44,607,769
G
Flot1
flotillin 1
increases expression
EXP
valdecoxib results in increased expression of FLOT1 mRNA
CTD
PMID:24136188
NCBI chr20:2,917,864...2,927,993
Ensembl chr20:2,917,137...2,927,978
G
Fmo1
flavin containing dimethylaniline monoxygenase 1
decreases expression
EXP
valdecoxib results in decreased expression of FMO1 mRNA
CTD
PMID:24136188
NCBI chr13:75,182,184...75,214,439
Ensembl chr13:75,182,176...75,214,647
G
Foxa1
forkhead box A1
decreases expression
EXP
valdecoxib results in decreased expression of FOXA1 mRNA
CTD
PMID:24136188
NCBI chr 6:75,099,907...75,136,534
Ensembl chr 6:75,103,503...75,136,188
G
Fzd7
frizzled class receptor 7
increases expression
EXP
valdecoxib results in increased expression of FZD7 mRNA
CTD
PMID:24136188
NCBI chr 9:60,931,433...60,934,252
Ensembl chr 9:60,930,875...60,935,781
G
G6pc1
glucose-6-phosphatase catalytic subunit 1
decreases expression
EXP
valdecoxib results in decreased expression of G6PC1 mRNA
CTD
PMID:24136188
NCBI chr10:86,307,400...86,318,766
Ensembl chr10:86,257,668...86,333,804
G
Gaa
alpha glucosidase
increases expression
EXP
valdecoxib results in increased expression of GAA mRNA
CTD
PMID:24136188
NCBI chr10:104,529,673...104,546,836
Ensembl chr10:104,529,747...104,546,836
G
Gabarapl1
GABA type A receptor associated protein like 1
increases expression
EXP
valdecoxib results in increased expression of GABARAPL1 mRNA
CTD
PMID:24136188
NCBI chr 4:162,980,309...162,989,452
Ensembl chr 4:162,980,249...162,989,450
G
Galm
galactose mutarotase
decreases expression
EXP
valdecoxib results in decreased expression of GALM mRNA
CTD
PMID:24136188
NCBI chr 6:14,837,540...14,889,484
Ensembl chr 6:14,837,548...14,889,310
G
Gclc
glutamate-cysteine ligase, catalytic subunit
increases expression
EXP
valdecoxib results in increased expression of GCLC mRNA
CTD
PMID:24136188
NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544
G
Gclm
glutamate cysteine ligase, modifier subunit
increases expression
EXP
valdecoxib results in increased expression of GCLM mRNA
CTD
PMID:24136188
NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535
G
Gda
guanine deaminase
increases expression
EXP
valdecoxib results in increased expression of GDA mRNA
CTD
PMID:24136188
NCBI chr 1:218,903,045...218,982,360
Ensembl chr 1:218,906,815...218,982,416
G
Ggcx
gamma-glutamyl carboxylase
decreases expression
EXP
valdecoxib results in decreased expression of GGCX mRNA
CTD
PMID:24136188
NCBI chr 4:104,469,737...104,485,631
Ensembl chr 4:104,469,765...104,487,063
G
Ggh
gamma-glutamyl hydrolase
increases expression
EXP
valdecoxib results in increased expression of GGH mRNA
CTD
PMID:24136188
NCBI chr 5:33,529,880...33,552,790
Ensembl chr 5:33,529,880...33,552,787
G
Ghr
growth hormone receptor
decreases expression
EXP
valdecoxib results in decreased expression of GHR mRNA
CTD
PMID:24136188
NCBI chr 2:52,541,452...52,804,960
Ensembl chr 2:52,542,594...52,804,735
G
Gja1
gap junction protein, alpha 1
increases expression
EXP
valdecoxib results in increased expression of GJA1 mRNA
CTD
PMID:24136188
NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582
G
Gjb2
gap junction protein, beta 2
increases expression
EXP
valdecoxib results in increased expression of GJB2 mRNA
CTD
PMID:24136188
NCBI chr15:31,260,390...31,278,222
Ensembl chr15:31,260,357...31,278,177
G
Gldc
glycine decarboxylase
decreases expression
EXP
valdecoxib results in decreased expression of GLDC mRNA
CTD
PMID:24136188
NCBI chr 1:227,883,249...227,962,119
Ensembl chr 1:227,883,249...227,962,097
G
Glrx
glutaredoxin
decreases expression
EXP
valdecoxib results in decreased expression of GLRX mRNA
CTD
PMID:24136188
NCBI chr 2:5,341,873...5,351,686
Ensembl chr 2:5,341,885...5,351,680
G
Gls2
glutaminase 2
decreases expression
EXP
valdecoxib results in decreased expression of GLS2 mRNA
CTD
PMID:24136188
NCBI chr 7:617,252...633,424
Ensembl chr 7:617,288...633,426
G
Glud1
glutamate dehydrogenase 1
decreases expression
EXP
valdecoxib results in decreased expression of GLUD1 mRNA
CTD
PMID:24136188
NCBI chr16:9,640,312...9,673,961
Ensembl chr16:9,640,312...9,673,957
G
Glul
glutamate-ammonia ligase
decreases expression
EXP
valdecoxib results in decreased expression of GLUL mRNA
CTD
PMID:24136188
NCBI chr13:65,969,053...66,035,121
Ensembl chr13:66,025,630...66,035,108
G
Gm2a
ganglioside GM2 activator
decreases expression
EXP
valdecoxib results in decreased expression of GM2A mRNA
CTD
PMID:24136188
NCBI chr10:39,219,221...39,231,756
Ensembl chr10:39,219,243...39,231,757
G
Gnmt
glycine N-methyltransferase
decreases expression
EXP
valdecoxib results in decreased expression of GNMT mRNA
CTD
PMID:24136188
NCBI chr 9:14,254,675...14,258,028
Ensembl chr 9:14,254,675...14,258,434
G
Gns
glucosamine (N-acetyl)-6-sulfatase
decreases expression
EXP
valdecoxib results in decreased expression of GNS mRNA
CTD
PMID:24136188
NCBI chr 7:56,889,148...56,923,173
Ensembl chr 7:56,889,232...56,923,151
G
Golph3l
golgi phosphoprotein 3-like
decreases expression
EXP
valdecoxib results in decreased expression of GOLPH3L mRNA
CTD
PMID:24136188
NCBI chr 2:183,151,941...183,183,094
Ensembl chr 2:183,153,301...183,183,083
G
Got1
glutamic-oxaloacetic transaminase 1
decreases expression
EXP
valdecoxib results in decreased expression of GOT1 mRNA
CTD
PMID:24136188
NCBI chr 1:242,357,293...242,381,535
Ensembl chr 1:242,357,306...242,380,633
G
Gpam
glycerol-3-phosphate acyltransferase, mitochondrial
decreases expression
EXP
valdecoxib results in decreased expression of GPAM mRNA
CTD
PMID:24136188
NCBI chr 1:254,106,323...254,170,755
Ensembl chr 1:254,106,331...254,142,639
G
Gpcpd1
glycerophosphocholine phosphodiesterase 1
decreases expression
EXP
valdecoxib results in decreased expression of GPCPD1 mRNA
CTD
PMID:24136188
NCBI chr 3:119,787,681...119,832,550
Ensembl chr 3:119,787,682...119,832,517
G
Gpd1
glycerol-3-phosphate dehydrogenase 1
decreases expression
EXP
valdecoxib results in decreased expression of GPD1 mRNA
CTD
PMID:24136188
NCBI chr 7:130,842,526...130,851,530
Ensembl chr 7:130,844,138...130,851,529
G
Gpld1
glycosylphosphatidylinositol specific phospholipase D1
decreases expression
EXP
valdecoxib results in decreased expression of GPLD1 mRNA
CTD
PMID:24136188
NCBI chr17:40,084,427...40,132,035
Ensembl chr17:40,084,617...40,126,939
G
Gpt2
glutamic--pyruvic transaminase 2
decreases expression
EXP
valdecoxib results in decreased expression of GPT2 mRNA
CTD
PMID:24136188
NCBI chr19:21,526,800...21,561,314
Ensembl chr19:21,517,621...21,560,610
G
Gpx2
glutathione peroxidase 2
increases expression
EXP
valdecoxib results in increased expression of GPX2 mRNA
CTD
PMID:24136188
NCBI chr 6:95,493,589...95,496,877
Ensembl chr 6:95,493,589...95,496,877
G
Grpel2
GrpE-like 2, mitochondrial
increases expression
EXP
valdecoxib results in increased expression of GRPEL2 mRNA
CTD
PMID:24136188
NCBI chr18:55,167,831...55,180,073
Ensembl chr18:55,168,209...55,180,180
G
Gsr
glutathione-disulfide reductase
increases expression
EXP
valdecoxib results in increased expression of GSR mRNA
CTD
PMID:24136188
NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
G
Gss
glutathione synthetase
increases expression
EXP
valdecoxib results in increased expression of GSS mRNA
CTD
PMID:24136188
NCBI chr 3:144,047,849...144,078,197
Ensembl chr 3:144,047,850...144,078,198
G
Gsta3
glutathione S-transferase alpha 3
increases expression
EXP
valdecoxib results in increased expression of GSTA3 mRNA
CTD
PMID:24136188
NCBI chr 9:23,658,574...23,684,240
Ensembl chr 9:23,658,574...23,684,240
G
Gstm4
glutathione S-transferase mu 4
increases expression
EXP
valdecoxib results in increased expression of GSTM4 mRNA
CTD
PMID:24136188
NCBI chr 2:195,667,940...195,685,315
Ensembl chr 2:195,680,004...195,685,323
G
Gtf2h1
general transcription factor IIH subunit 1
increases expression
EXP
valdecoxib results in increased expression of GTF2H1 mRNA
CTD
PMID:24136188
NCBI chr 1:97,321,417...97,349,455
Ensembl chr 1:97,321,394...97,349,455
G
Hao2
hydroxyacid oxidase 2
decreases expression
EXP
valdecoxib results in decreased expression of HAO2 mRNA
CTD
PMID:24136188
NCBI chr 2:186,200,137...186,232,997
Ensembl chr 2:186,200,504...186,224,425
G
Hcfc2
host cell factor C2
increases expression
EXP
valdecoxib results in increased expression of HCFC2 mRNA
CTD
PMID:24136188
NCBI chr 7:20,983,986...21,019,826
Ensembl chr 7:20,991,017...21,019,801
G
Hdac11
histone deacetylase 11
decreases expression
EXP
valdecoxib results in decreased expression of HDAC11 mRNA
CTD
PMID:24136188
NCBI chr 4:123,645,873...123,667,407
Ensembl chr 4:123,650,157...123,667,405
G
Hdac2
histone deacetylase 2
decreases expression
EXP
valdecoxib results in decreased expression of HDAC2 mRNA
CTD
PMID:24136188
NCBI chr20:40,548,244...40,571,609
Ensembl chr20:40,548,250...40,571,609
G
Hdgf
heparin binding growth factor
increases expression
EXP
valdecoxib results in increased expression of HDGF mRNA
CTD
PMID:24136188
NCBI chr 2:173,370,147...173,379,756
Ensembl chr 2:173,370,465...173,379,747
G
Herpud1
homocysteine inducible ER protein with ubiquitin like domain 1
decreases expression
EXP
valdecoxib results in decreased expression of HERPUD1 mRNA
CTD
PMID:24136188
NCBI chr19:10,598,411...10,609,002
Ensembl chr19:10,598,417...10,618,424
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Hes6
hes family bHLH transcription factor 6
decreases expression
EXP
valdecoxib results in decreased expression of HES6 mRNA
CTD
PMID:24136188
NCBI chr 9:92,001,849...92,003,562
Ensembl chr 9:92,001,841...92,003,559
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Hibch
3-hydroxyisobutyryl-CoA hydrolase
increases expression
EXP
valdecoxib results in increased expression of HIBCH mRNA
CTD
PMID:24136188
NCBI chr 9:48,590,097...48,669,896
Ensembl chr 9:48,590,099...48,669,824
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Hikeshi
heat shock protein nuclear import factor hikeshi
increases expression
EXP
valdecoxib results in increased expression of HIKESHI mRNA
CTD
PMID:24136188
NCBI chr 1:143,825,399...143,849,361
Ensembl chr 1:143,825,923...143,849,363
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Hirip3
HIRA interacting protein 3
increases expression
EXP
valdecoxib results in increased expression of HIRIP3 mRNA
CTD
PMID:24136188
NCBI chr 1:181,472,537...181,475,082
Ensembl chr 1:181,472,056...181,475,079
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Hist1h4b
histone cluster 1 H4 family member B
decreases expression
EXP
valdecoxib results in decreased expression of HIST1H4B mRNA
CTD
PMID:24136188
NCBI chr17:42,480,467...42,484,912
Ensembl chr17:42,480,313...42,485,370
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Hlcs
holocarboxylase synthetase
increases expression
EXP
valdecoxib results in increased expression of HLCS mRNA
CTD
PMID:24136188
NCBI chr11:33,455,806...33,635,197
Ensembl chr11:33,455,809...33,624,222
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Hmgcs1
3-hydroxy-3-methylglutaryl-CoA synthase 1
increases expression
EXP
valdecoxib results in increased expression of HMGCS1 mRNA
CTD
PMID:24136188
NCBI chr 2:51,649,368...51,667,100
Ensembl chr 2:51,649,497...51,667,100
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Hmgn1
high mobility group nucleosome binding domain 1
increases expression
EXP
valdecoxib results in increased expression of HMGN1 mRNA
CTD
PMID:24136188
NCBI chr11:35,422,328...35,428,247
Ensembl chr11:35,422,328...35,428,254
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Hmgn2
high mobility group nucleosomal binding domain 2
decreases expression
EXP
valdecoxib results in decreased expression of HMGN2 mRNA
CTD
PMID:24136188
NCBI chr 5:146,192,126...146,195,580
Ensembl chr 5:146,192,126...146,195,521 Ensembl chr16:146,192,126...146,195,521
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Hmgn3
high mobility group nucleosomal binding domain 3
increases expression
EXP
valdecoxib results in increased expression of HMGN3 mRNA
CTD
PMID:24136188
NCBI chr 8:84,022,493...84,059,329
Ensembl chr 8:84,022,495...84,062,976
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Hoga1
4-hydroxy-2-oxoglutarate aldolase 1
decreases expression
EXP
valdecoxib results in decreased expression of HOGA1 mRNA
CTD
PMID:24136188
NCBI chr 1:240,856,991...240,884,243
Ensembl chr 1:240,857,126...240,884,568
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Hsd17b13
hydroxysteroid (17-beta) dehydrogenase 13
decreases expression
EXP
valdecoxib results in decreased expression of HSD17B13 mRNA
CTD
PMID:24136188
NCBI chr14:5,751,697...5,766,809
Ensembl chr14:5,752,132...5,768,166
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Hsdl2
hydroxysteroid dehydrogenase like 2
increases expression
EXP
valdecoxib results in increased expression of HSDL2 mRNA
CTD
PMID:24136188
NCBI chr 5:74,443,933...74,479,104
Ensembl chr 5:74,443,872...74,479,839
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Hsp90aa1
heat shock protein 90 alpha family class A member 1
increases expression
EXP
valdecoxib results in increased expression of HSP90AA1 mRNA
CTD
PMID:24136188
NCBI chr 6:129,702,376...129,707,907
Ensembl chr 6:129,702,383...129,707,268
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Hsp90ab1
heat shock protein 90 alpha family class B member 1
increases expression
EXP
valdecoxib results in increased expression of HSP90AB1 mRNA
CTD
PMID:24136188
NCBI chr 9:15,432,986...15,438,358
Ensembl chr 9:15,433,691...15,438,488
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Hspb1
heat shock protein family B (small) member 1
increases expression
EXP
valdecoxib results in increased expression of HSPB1 mRNA
CTD
PMID:24136188
NCBI chr12:20,794,014...20,795,675
Ensembl chr12:20,794,028...20,795,743
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Hspb8
heat shock protein family B (small) member 8
increases expression
EXP
valdecoxib results in increased expression of HSPB8 mRNA
CTD
PMID:24136188
NCBI chr12:40,176,405...40,205,002
Ensembl chr12:40,176,532...40,191,185
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Hsph1
heat shock protein family H (Hsp110) member 1
increases expression
EXP
valdecoxib results in increased expression of HSPH1 mRNA
CTD
PMID:24136188
NCBI chr12:5,390,916...5,410,224
Ensembl chr12:5,390,922...5,410,224
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Htatip2
HIV-1 Tat interactive protein 2
increases expression
EXP
valdecoxib results in increased expression of HTATIP2 mRNA
CTD
PMID:24136188
NCBI chr 1:99,473,411...99,488,632
Ensembl chr 1:99,469,245...99,488,629
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Hyal3
hyaluronidase 3
decreases expression
EXP
valdecoxib results in decreased expression of HYAL3 mRNA
CTD
PMID:24136188
NCBI chr 8:108,254,385...108,260,020
Ensembl chr 8:108,250,667...108,260,647
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Ide
insulin degrading enzyme
increases expression
EXP
valdecoxib results in increased expression of IDE mRNA
CTD
PMID:24136188
NCBI chr 1:235,002,984...235,102,448
Ensembl chr 1:234,995,351...235,102,440
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Idi1
isopentenyl-diphosphate delta isomerase 1
increases expression
EXP
valdecoxib results in increased expression of IDI1 mRNA
CTD
PMID:24136188
NCBI chr17:61,629,592...61,637,357
Ensembl chr17:61,629,594...61,637,357
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Ifitm3
interferon induced transmembrane protein 3
increases expression
EXP
valdecoxib results in increased expression of IFITM3 mRNA
CTD
PMID:24136188
NCBI chr 1:196,111,026...196,112,135
Ensembl chr 1:196,111,043...196,112,203
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Ifng
interferon gamma
increases expression
EXP
valdecoxib results in increased expression of IFNG
CTD
PMID:24136188
NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
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Ift25
intraflagellar transport 25
increases expression
EXP
valdecoxib results in increased expression of IFT25 mRNA
CTD
PMID:24136188
NCBI chr 5:122,035,588...122,062,421
Ensembl chr 5:122,035,581...122,062,421
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Igfbp3
insulin-like growth factor binding protein 3
decreases expression
EXP
valdecoxib results in decreased expression of IGFBP3 mRNA
CTD
PMID:24136188
NCBI chr14:82,056,347...82,064,083
Ensembl chr14:82,056,347...82,064,083
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Il13ra1
interleukin 13 receptor subunit alpha 1
increases expression
EXP
valdecoxib results in increased expression of IL13RA1 mRNA
CTD
PMID:24136188
NCBI chr X:115,348,822...115,408,682
Ensembl chr X:115,348,860...115,408,681 Ensembl chr11:115,348,860...115,408,681
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Il6
interleukin 6
increases expression
EXP
valdecoxib results in increased expression of IL6
CTD
PMID:24136188
NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
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Impact
impact RWD domain protein
increases expression
EXP
valdecoxib results in increased expression of IMPACT mRNA
CTD
PMID:24136188
NCBI chr18:4,108,872...4,147,571
Ensembl chr18:4,108,853...4,147,569
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Inhbc
inhibin subunit beta C
decreases expression
EXP
valdecoxib results in decreased expression of INHBC mRNA
CTD
PMID:24136188
NCBI chr 7:63,184,141...63,197,630
Ensembl chr 7:63,184,142...63,197,630
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Inhbe
inhibin subunit beta E
decreases expression
EXP
valdecoxib results in decreased expression of INHBE mRNA
CTD
PMID:24136188
NCBI chr 7:63,176,221...63,179,209
Ensembl chr 7:63,176,219...63,179,172
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Inmt
indolethylamine N-methyltransferase
increases expression
EXP
valdecoxib results in increased expression of INMT mRNA
CTD
PMID:24136188
NCBI chr 4:84,318,197...84,322,493
Ensembl chr 4:84,318,197...84,322,493
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Insig2
insulin induced gene 2
increases expression
EXP
valdecoxib results in increased expression of INSIG2 mRNA
CTD
PMID:24136188
NCBI chr13:32,472,390...32,500,139
Ensembl chr13:32,473,742...32,494,923
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Ip6k2
inositol hexakisphosphate kinase 2
decreases expression
EXP
valdecoxib results in decreased expression of IP6K2 mRNA
CTD
PMID:24136188
NCBI chr 8:109,483,843...109,510,172
Ensembl chr 8:109,484,310...109,510,166
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Ipo4
importin 4
increases expression
EXP
valdecoxib results in increased expression of IPO4 mRNA
CTD
PMID:24136188
NCBI chr15:29,117,365...29,127,382
Ensembl chr15:29,117,365...29,127,285
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Irak1
interleukin-1 receptor-associated kinase 1
increases expression
EXP
valdecoxib results in increased expression of IRAK1 mRNA
CTD
PMID:24136188
NCBI chr X:151,768,621...151,778,521
Ensembl chr X:151,768,777...151,778,521
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Islr
immunoglobulin superfamily containing leucine-rich repeat
decreases expression
EXP
valdecoxib results in decreased expression of ISLR mRNA
CTD
PMID:24136188
NCBI chr 8:58,571,155...58,574,128
Ensembl chr 8:58,570,777...58,574,130
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Isyna1
inositol-3-phosphate synthase 1
increases expression
EXP
valdecoxib results in increased expression of ISYNA1 mRNA
CTD
PMID:24136188
NCBI chr16:18,839,143...18,841,979
Ensembl chr16:18,839,145...18,841,979
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Ivd
isovaleryl-CoA dehydrogenase
decreases expression
EXP
valdecoxib results in decreased expression of IVD mRNA
CTD
PMID:24136188
NCBI chr 3:105,851,710...105,872,144
Ensembl chr 3:105,851,683...105,872,575
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Jpt1
Jupiter microtubule associated homolog 1
increases expression
EXP
valdecoxib results in increased expression of JPT1 mRNA
CTD
PMID:24136188
NCBI chr10:100,744,468...100,762,504
Ensembl chr10:100,686,797...100,784,513
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Junb
JunB proto-oncogene, AP-1 transcription factor subunit
increases expression
EXP
valdecoxib results in increased expression of JUNB mRNA
CTD
PMID:24136188
NCBI chr19:23,176,265...23,178,049
Ensembl chr19:23,176,294...23,178,035
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Kcmf1
potassium channel modulatory factor 1
increases expression
EXP
valdecoxib results in increased expression of KCMF1 mRNA
CTD
PMID:24136188
NCBI chr 4:104,888,452...104,950,234
Ensembl chr 4:104,889,847...104,950,234
G
Kcnj8
potassium inwardly-rectifying channel, subfamily J, member 8
increases expression
EXP
valdecoxib results in increased expression of KCNJ8 mRNA
CTD
PMID:24136188
NCBI chr 4:175,508,908...175,515,829
Ensembl chr 4:175,508,912...175,515,603
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Kdsr
3-ketodihydrosphingosine reductase
decreases expression
EXP
valdecoxib results in decreased expression of KDSR mRNA
CTD
PMID:24136188
NCBI chr13:22,862,117...22,894,118
Ensembl chr13:22,862,117...22,894,108
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Keap1
Kelch-like ECH-associated protein 1
increases expression
EXP
valdecoxib results in increased expression of KEAP1 mRNA
CTD
PMID:24136188
NCBI chr 8:19,768,375...19,777,862
Ensembl chr 8:19,768,375...19,777,862
G
Khk
ketohexokinase
decreases expression
EXP
valdecoxib results in decreased expression of KHK mRNA
CTD
PMID:24136188
NCBI chr 6:25,445,298...25,455,834
Ensembl chr 6:25,445,300...25,455,717
G
Kif21a
kinesin family member 21A
increases expression
EXP
valdecoxib results in increased expression of KIF21A mRNA
CTD
PMID:24136188
NCBI chr 7:122,062,523...122,179,051
Ensembl chr 7:122,062,537...122,178,999
G
Klf15
KLF transcription factor 15
decreases expression
EXP
valdecoxib results in decreased expression of KLF15 mRNA
CTD
PMID:24136188
NCBI chr 4:122,965,718...122,978,403
Ensembl chr 4:122,965,807...122,978,374
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Klhl24
kelch-like family member 24
increases expression
EXP
valdecoxib results in increased expression of KLHL24 mRNA
CTD
PMID:24136188
NCBI chr11:80,843,621...80,877,649
Ensembl chr11:80,846,755...80,877,636
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Klrg1
killer cell lectin like receptor G1
decreases expression
EXP
valdecoxib results in decreased expression of KLRG1 mRNA
CTD
PMID:24136188
NCBI chr 4:155,455,465...155,467,301
Ensembl chr 4:155,455,495...155,467,424
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Kmt2a
lysine methyltransferase 2A
increases expression
EXP
valdecoxib results in increased expression of KMT2A mRNA
CTD
PMID:24136188
NCBI chr 8:45,116,763...45,193,320
Ensembl chr 8:45,118,814...45,193,181
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Krt8
keratin 8
increases expression
EXP
valdecoxib results in increased expression of KRT8 mRNA
CTD
PMID:24136188
NCBI chr 7:133,124,203...133,131,656
Ensembl chr 7:133,124,203...133,131,728
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Kxd1
KxDL motif containing 1
increases expression
EXP
valdecoxib results in increased expression of KXD1 mRNA
CTD
PMID:24136188
NCBI chr16:18,895,343...18,916,266
Ensembl chr16:18,900,616...18,920,807
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Kyat1
kynurenine aminotransferase 1
increases expression
EXP
valdecoxib results in increased expression of KYAT1 mRNA
CTD
PMID:24136188
NCBI chr 3:13,459,598...13,493,308
Ensembl chr 3:13,459,591...13,493,355
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L3hypdh
trans-L-3-hydroxyproline dehydratase
decreases expression
EXP
valdecoxib results in decreased expression of L3HYPDH mRNA
CTD
PMID:24136188
NCBI chr 6:90,636,310...90,647,106
Ensembl chr 6:90,636,310...90,647,106
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Lama3
laminin subunit alpha 3
decreases expression
EXP
valdecoxib results in decreased expression of LAMA3 mRNA
CTD
PMID:24136188
NCBI chr18:3,523,168...3,751,722
Ensembl chr18:3,523,133...3,751,353
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Lamtor1
late endosomal/lysosomal adaptor, MAPK and MTOR activator 1
increases expression
EXP
valdecoxib results in increased expression of LAMTOR1 mRNA
CTD
PMID:24136188
NCBI chr 1:156,272,116...156,277,687
Ensembl chr 1:156,272,064...156,291,179
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Lbh
LBH regulator of WNT signaling pathway
decreases expression
EXP
valdecoxib results in decreased expression of LBH mRNA
CTD
PMID:24136188
NCBI chr 6:22,569,238...22,593,056
Ensembl chr 6:22,568,834...22,593,079
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Lbp
lipopolysaccharide binding protein
increases expression
EXP
valdecoxib results in increased expression of LBP mRNA
CTD
PMID:24136188
NCBI chr 3:146,953,889...146,981,032
Ensembl chr 3:146,954,015...146,981,586
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Lcmt1
leucine carboxyl methyltransferase 1
decreases expression
EXP
valdecoxib results in decreased expression of LCMT1 mRNA
CTD
PMID:24136188
NCBI chr 1:177,904,119...177,960,111
Ensembl chr 1:177,904,139...177,960,112
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Lgals3
galectin 3
increases expression
EXP
valdecoxib results in increased expression of LGALS3 mRNA
CTD
PMID:24136188
NCBI chr15:20,620,083...20,632,019
Ensembl chr15:20,607,692...20,632,025
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Lgals8
galectin 8
increases expression
EXP
valdecoxib results in increased expression of LGALS8 mRNA
CTD
PMID:24136188
NCBI chr17:58,024,652...58,052,764
Ensembl chr17:58,028,105...58,052,764
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Lhpp
phospholysine phosphohistidine inorganic pyrophosphate phosphatase
decreases expression
EXP
valdecoxib results in decreased expression of LHPP mRNA
CTD
PMID:24136188
NCBI chr 1:187,403,390...187,494,577
Ensembl chr 1:187,403,433...187,494,578
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Lipa
lipase A, lysosomal acid type
increases expression
EXP
valdecoxib results in increased expression of LIPA mRNA
CTD
PMID:24136188
NCBI chr 1:232,024,351...232,057,735
Ensembl chr 1:232,024,356...232,057,633
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Lipc
lipase C, hepatic type
decreases expression
EXP
valdecoxib results in decreased expression of LIPC mRNA
CTD
PMID:24136188
NCBI chr 8:71,509,633...71,635,663
Ensembl chr 8:71,509,635...71,635,464
G
Lmnb1
lamin B1
increases expression
EXP
valdecoxib results in increased expression of LMNB1 mRNA
CTD
PMID:24136188
NCBI chr18:50,175,861...50,215,210
Ensembl chr18:50,175,874...50,214,502
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Lmo7
LIM domain 7
decreases expression
EXP
valdecoxib results in decreased expression of LMO7 mRNA
CTD
PMID:24136188
NCBI chr15:78,566,999...78,769,833
Ensembl chr15:78,567,023...78,769,783
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Lpar6
lysophosphatidic acid receptor 6
increases expression
EXP
valdecoxib results in increased expression of LPAR6 mRNA
CTD
PMID:24136188
NCBI chr15:48,416,548...48,418,357
Ensembl chr15:48,416,544...48,422,331
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Lrat
lecithin retinol acyltransferase
decreases expression
EXP
valdecoxib results in decreased expression of LRAT mRNA
CTD
PMID:24136188
NCBI chr 2:168,264,093...168,273,155
Ensembl chr 2:168,266,877...168,273,619
G
Lrp11
LDL receptor related protein 11
decreases expression
EXP
valdecoxib results in decreased expression of LRP11 mRNA
CTD
PMID:24136188
NCBI chr 1:2,048,307...2,108,115
Ensembl chr 1:2,079,438...2,108,110
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Lrp3
LDL receptor related protein 3
decreases expression
EXP
valdecoxib results in decreased expression of LRP3 mRNA
CTD
PMID:24136188
NCBI chr 1:87,843,815...87,859,147
Ensembl chr 1:87,844,868...87,859,110
G
Lrp5
LDL receptor related protein 5
decreases expression
EXP
valdecoxib results in decreased expression of LRP5 mRNA
CTD
PMID:24136188
NCBI chr 1:200,814,247...200,917,581
Ensembl chr 1:200,814,250...200,917,581
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Lrp6
LDL receptor related protein 6
decreases expression
EXP
valdecoxib results in decreased expression of LRP6 mRNA
CTD
PMID:24136188
NCBI chr 4:167,269,856...167,400,364
Ensembl chr 4:167,270,353...167,400,497
G
Lrrc8b
leucine rich repeat containing 8 VRAC subunit B
decreases expression
EXP
valdecoxib results in decreased expression of LRRC8B mRNA
CTD
PMID:24136188
NCBI chr14:4,350,462...4,416,336
Ensembl chr14:4,354,508...4,416,311
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Lrrfip1
LRR binding FLII interacting protein 1
increases expression
EXP
valdecoxib results in increased expression of LRRFIP1 mRNA
CTD
PMID:24136188
NCBI chr 9:91,592,032...91,720,250
Ensembl chr 9:91,643,197...91,720,250
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Lss
lanosterol synthase
increases expression
EXP
valdecoxib results in increased expression of LSS mRNA
CTD
PMID:24136188
NCBI chr20:12,091,138...12,118,858
Ensembl chr20:12,092,774...12,118,762
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Ltbr
lymphotoxin beta receptor
increases expression
EXP
valdecoxib results in increased expression of LTBR mRNA
CTD
PMID:24136188
NCBI chr 4:158,108,884...158,115,339
Ensembl chr 4:158,108,886...158,121,539
G
Luc7l
LUC7-like
increases expression
EXP
valdecoxib results in increased expression of LUC7L mRNA
CTD
PMID:24136188
NCBI chr10:15,273,340...15,307,131
Ensembl chr10:15,273,348...15,303,112
G
Lysmd2
LysM domain containing 2
increases expression
EXP
valdecoxib results in increased expression of LYSMD2 mRNA
CTD
PMID:24136188
NCBI chr 8:76,378,984...76,394,396
Ensembl chr 8:76,379,219...76,394,654
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Lyst
lysosomal trafficking regulator
decreases expression
EXP
valdecoxib results in decreased expression of LYST mRNA
CTD
PMID:24136188
NCBI chr17:86,241,384...86,443,501
Ensembl chr17:86,241,384...86,443,480
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Macrod1
mono-ADP ribosylhydrolase 1
decreases expression
EXP
valdecoxib results in decreased expression of MACROD1 mRNA
CTD
PMID:24136188
NCBI chr 1:204,246,238...204,387,027
Ensembl chr 1:204,246,166...204,389,716
G
Mafb
MAF bZIP transcription factor B
decreases expression
EXP
valdecoxib results in decreased expression of MAFB mRNA
CTD
PMID:24136188
NCBI chr 3:148,998,111...149,000,031
Ensembl chr 3:148,998,122...149,000,031
G
Mafk
MAF bZIP transcription factor K
increases expression
EXP
valdecoxib results in increased expression of MAFK mRNA
CTD
PMID:24136188
NCBI chr12:14,834,628...14,856,414
Ensembl chr12:14,833,984...14,837,048 Ensembl chr12:14,833,984...14,837,048
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Mal2
mal, T-cell differentiation protein 2
increases expression
EXP
valdecoxib results in increased expression of MAL2 mRNA
CTD
PMID:24136188
NCBI chr 7:85,900,453...85,933,433
Ensembl chr 7:85,900,453...85,933,429
G
Malsu1
mitochondrial assembly of ribosomal large subunit 1
increases expression
EXP
valdecoxib results in increased expression of MALSU1 mRNA
CTD
PMID:24136188
NCBI chr 4:78,051,090...78,059,913
Ensembl chr 4:78,051,059...78,059,905
G
Manba
mannosidase beta
increases expression
EXP
valdecoxib results in increased expression of MANBA mRNA
CTD
PMID:24136188
NCBI chr 2:223,910,432...224,002,988
Ensembl chr 2:223,910,432...224,002,983
G
Map2k2
mitogen activated protein kinase kinase 2
increases expression
EXP
valdecoxib results in increased expression of MAP2K2 mRNA
CTD
PMID:24136188
NCBI chr 7:8,590,729...8,610,279
Ensembl chr 7:8,580,905...8,610,243
G
Mapkapk2
MAPK activated protein kinase 2
decreases expression
EXP
valdecoxib results in decreased expression of MAPKAPK2 mRNA
CTD
PMID:24136188
NCBI chr13:42,513,762...42,560,061
Ensembl chr13:42,513,762...42,560,457
G
Marchf2
membrane associated ring-CH-type finger 2
decreases expression
EXP
valdecoxib results in decreased expression of MARCHF2 mRNA
CTD
PMID:24136188
NCBI chr 7:14,480,605...14,507,821
Ensembl chr 7:14,481,761...14,507,794
G
Marchf5
membrane associated ring-CH-type finger 5
increases expression
EXP
valdecoxib results in increased expression of MARCHF5 mRNA
CTD
PMID:24136188
NCBI chr 1:234,931,137...234,953,849
Ensembl chr 1:234,931,271...234,952,632
G
Mcoln1
mucolipin TRP cation channel 1
increases expression
EXP
valdecoxib results in increased expression of MCOLN1 mRNA
CTD
PMID:24136188
NCBI chr12:1,560,341...1,574,252
Ensembl chr12:1,560,359...1,574,252
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Mdh1
malate dehydrogenase 1
decreases expression
EXP
valdecoxib results in decreased expression of MDH1 mRNA
CTD
PMID:24136188
NCBI chr14:95,630,625...95,645,920
Ensembl chr14:95,630,306...95,645,925
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Mdm2
MDM2 proto-oncogene
increases expression
EXP
valdecoxib results in increased expression of MDM2 mRNA
CTD
PMID:24136188
NCBI chr 7:53,290,660...53,315,205
Ensembl chr 7:53,290,664...53,314,915
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Mdp1
magnesium-dependent phosphatase 1
decreases expression
EXP
valdecoxib results in decreased expression of MDP1 mRNA
CTD
PMID:24136188
NCBI chr15:29,148,994...29,151,868
Ensembl chr15:29,148,994...29,151,905
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Me1
malic enzyme 1
increases expression
EXP
valdecoxib results in increased expression of ME1 mRNA
CTD
PMID:24136188
NCBI chr 8:87,549,043...87,660,251
Ensembl chr 8:87,549,043...87,660,304
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Meox2
mesenchyme homeobox 2
increases expression
EXP
valdecoxib results in increased expression of MEOX2 mRNA
CTD
PMID:24136188
NCBI chr 6:53,856,760...53,917,467
Ensembl chr 6:53,856,758...53,917,467
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Mfsd2a
MFSD2 lysolipid transporter A, lysophospholipid
decreases expression
EXP
valdecoxib results in decreased expression of MFSD2A mRNA
CTD
PMID:24136188
NCBI chr 5:135,225,801...135,240,744
Ensembl chr 5:135,225,816...135,240,690
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Mgat4b
alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B
decreases expression
EXP
valdecoxib results in decreased expression of MGAT4B mRNA
CTD
PMID:24136188
NCBI chr10:34,548,918...34,559,229
Ensembl chr10:34,549,433...34,559,229
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Mgll
monoglyceride lipase
increases expression
EXP
valdecoxib results in increased expression of MGLL mRNA
CTD
PMID:24136188
NCBI chr 4:121,192,186...121,294,187
Ensembl chr 4:121,192,195...121,294,179
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Mgst2
microsomal glutathione S-transferase 2
increases expression
EXP
valdecoxib results in increased expression of MGST2 mRNA
CTD
PMID:24136188
NCBI chr 2:135,679,524...135,715,828
Ensembl chr 2:135,693,557...135,715,828
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Mgst3
microsomal glutathione S-transferase 3
decreases expression
EXP
valdecoxib results in decreased expression of MGST3 mRNA
CTD
PMID:24136188
NCBI chr13:79,526,541...79,547,479
Ensembl chr13:79,526,541...79,547,411
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Mia2
MIA SH3 domain ER export factor 2
decreases expression
EXP
valdecoxib results in decreased expression of MIA2 mRNA
CTD
PMID:24136188
NCBI chr 6:76,787,508...76,885,246
Ensembl chr 6:76,787,508...76,885,211
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Midn
midnolin
increases expression
EXP
valdecoxib results in increased expression of MIDN mRNA
CTD
PMID:24136188
NCBI chr 7:9,548,100...9,559,605
Ensembl chr 7:9,549,650...9,559,752
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Mknk2
MAPK interacting serine/threonine kinase 2
decreases expression
EXP
valdecoxib results in decreased expression of MKNK2 mRNA
CTD
PMID:24136188
NCBI chr 7:9,039,771...9,050,832
Ensembl chr 7:9,039,728...9,050,827
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Mkrn1
makorin ring finger protein 1
decreases expression
EXP
valdecoxib results in decreased expression of MKRN1 mRNA
CTD
PMID:24136188
NCBI chr 4:68,175,908...68,197,216
Ensembl chr 4:68,175,909...68,197,165 Ensembl chr 9:68,175,909...68,197,165
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Mllt10
MLLT10, histone lysine methyltransferase DOT1L cofactor
increases expression
EXP
valdecoxib results in increased expression of MLLT10 mRNA
CTD
PMID:24136188
NCBI chr17:80,821,870...80,949,349
Ensembl chr17:80,822,556...80,949,345
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Mmgt1
membrane magnesium transporter 1
increases expression
EXP
valdecoxib results in increased expression of MMGT1 mRNA
CTD
PMID:24136188
NCBI chr X:134,408,463...134,420,798
Ensembl chr X:134,408,466...134,420,729
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Mospd2
motile sperm domain containing 2
increases expression
EXP
valdecoxib results in increased expression of MOSPD2 mRNA
CTD
PMID:24136188
NCBI chr X:29,420,485...29,472,099
Ensembl chr X:29,420,586...29,462,398
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Mpc1
mitochondrial pyruvate carrier 1
decreases expression
EXP
valdecoxib results in decreased expression of MPC1 mRNA
CTD
PMID:24136188
NCBI chr 1:52,437,745...52,449,399
Ensembl chr 1:52,437,741...52,449,400
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Mpc2
mitochondrial pyruvate carrier 2
increases expression
EXP
valdecoxib results in increased expression of MPC2 mRNA
CTD
PMID:24136188
NCBI chr13:77,728,176...77,747,664
Ensembl chr13:77,728,250...77,747,664
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Mphosph8
M-phase phosphoprotein 8
increases expression
EXP
valdecoxib results in increased expression of MPHOSPH8 mRNA
CTD
PMID:24136188
NCBI chr15:30,800,546...30,828,415
Ensembl chr15:30,686,613...30,828,810
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Mrpl14
mitochondrial ribosomal protein L14
increases expression
EXP
valdecoxib results in increased expression of MRPL14 mRNA
CTD
PMID:24136188
NCBI chr 9:15,302,840...15,315,195
Ensembl chr 9:15,302,427...15,315,267
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Mrpl38
mitochondrial ribosomal protein L38
increases expression
EXP
valdecoxib results in increased expression of MRPL38 mRNA
CTD
PMID:24136188
NCBI chr10:101,365,353...101,372,159
Ensembl chr10:101,365,353...101,372,171
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Mrpl49
mitochondrial ribosomal protein L49
increases expression
EXP
valdecoxib results in increased expression of MRPL49 mRNA
CTD
PMID:24136188
NCBI chr 1:203,346,068...203,350,040
Ensembl chr 1:203,332,481...203,350,049
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Mrpl51
mitochondrial ribosomal protein L51
increases expression
EXP
valdecoxib results in increased expression of MRPL51 mRNA
CTD
PMID:24136188
NCBI chr 4:157,991,756...157,994,715
Ensembl chr 4:157,992,408...157,995,414
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Mrpl55
mitochondrial ribosomal protein L55
increases expression
EXP
valdecoxib results in increased expression of MRPL55 mRNA
CTD
PMID:24136188
NCBI chr10:43,988,676...43,991,841
Ensembl chr10:43,988,683...43,991,841
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Mrps18b
mitochondrial ribosomal protein S18B
increases expression
EXP
valdecoxib results in increased expression of MRPS18B mRNA
CTD
PMID:24136188
NCBI chr20:2,838,174...2,844,260
Ensembl chr20:2,838,030...2,844,260
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Mrps27
mitochondrial ribosomal protein S27
increases expression
EXP
valdecoxib results in increased expression of MRPS27 mRNA
CTD
PMID:24136188
NCBI chr 2:30,740,007...30,808,577
Ensembl chr 2:30,740,033...30,808,577
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Msmo1
methylsterol monooxygenase 1
increases expression
EXP
valdecoxib results in increased expression of MSMO1 mRNA
CTD
PMID:24136188
NCBI chr16:24,980,680...24,997,927
Ensembl chr16:24,980,697...24,998,016
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Mtmr7
myotubularin related protein 7
decreases expression
EXP
valdecoxib results in decreased expression of MTMR7 mRNA
CTD
PMID:24136188
NCBI chr16:51,641,267...51,732,212
Ensembl chr16:51,641,190...51,732,182
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Mvk
mevalonate kinase
increases expression
EXP
valdecoxib results in increased expression of MVK mRNA
CTD
PMID:24136188
NCBI chr12:42,141,391...42,158,893
Ensembl chr12:42,141,384...42,158,882
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Myl9
myosin light chain 9
decreases expression
EXP
valdecoxib results in decreased expression of MYL9 mRNA
CTD
PMID:24136188
NCBI chr 3:145,281,943...145,288,333
Ensembl chr 3:145,281,937...145,288,333
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Myo1b
myosin Ib
decreases expression
EXP
valdecoxib results in decreased expression of MYO1B mRNA
CTD
PMID:24136188
NCBI chr 9:49,690,043...49,852,373
Ensembl chr 9:49,690,086...49,850,798
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Naa10
N(alpha)-acetyltransferase 10, NatA catalytic subunit
increases expression
EXP
valdecoxib results in increased expression of NAA10 mRNA
CTD
PMID:24136188
NCBI chr X:151,656,056...151,661,304
Ensembl chr X:151,656,056...151,661,252
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Nap1l1
nucleosome assembly protein 1-like 1
increases expression
EXP
valdecoxib results in increased expression of NAP1L1 mRNA
CTD
PMID:24136188
NCBI chr 7:46,933,278...46,957,853
Ensembl chr 7:46,933,356...46,956,593
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Ncald
neurocalcin delta
increases expression
EXP
valdecoxib results in increased expression of NCALD mRNA
CTD
PMID:24136188
NCBI chr 7:68,532,671...68,964,740
Ensembl chr 7:68,534,421...68,964,496
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Nectin2
nectin cell adhesion molecule 2
decreases expression
EXP
valdecoxib results in decreased expression of NECTIN2 mRNA
CTD
PMID:24136188
NCBI chr 1:79,372,123...79,407,379
Ensembl chr 1:79,372,119...79,407,360
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Nedd9
neural precursor cell expressed, developmentally down-regulated 9
increases expression
EXP
valdecoxib results in increased expression of NEDD9 mRNA
CTD
PMID:24136188
NCBI chr17:23,289,793...23,468,026
Ensembl chr17:23,282,326...23,468,019
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Nhp2
NHP2 ribonucleoprotein
increases expression
EXP
valdecoxib results in increased expression of NHP2 mRNA
CTD
PMID:24136188
NCBI chr10:35,877,057...35,880,399
Ensembl chr10:35,877,054...35,882,545
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Nipsnap1
nipsnap homolog 1
decreases expression
EXP
valdecoxib results in decreased expression of NIPSNAP1 mRNA
CTD
PMID:24136188
NCBI chr14:79,734,234...79,758,101
Ensembl chr14:79,734,209...79,758,098
G
Nmi
N-myc (and STAT) interactor
increases expression
EXP
valdecoxib results in increased expression of NMI mRNA
CTD
PMID:24136188
NCBI chr 3:36,415,607...36,439,716
Ensembl chr 3:36,415,607...36,439,498
G
Nnt
nicotinamide nucleotide transhydrogenase
decreases expression
EXP
valdecoxib results in decreased expression of NNT mRNA
CTD
PMID:24136188
NCBI chr 2:51,411,413...51,505,125
Ensembl chr 2:51,411,413...51,504,823
G
Noct
nocturnin
decreases expression
EXP
valdecoxib results in decreased expression of NOCT mRNA
CTD
PMID:24136188
NCBI chr 2:135,271,189...135,291,407
Ensembl chr 2:135,271,189...135,291,400
G
Nploc4
NPL4 homolog, ubiquitin recognition factor
increases expression
EXP
valdecoxib results in increased expression of NPLOC4 mRNA
CTD
PMID:24136188
NCBI chr10:105,654,395...105,709,958
Ensembl chr10:105,654,812...105,709,913
G
Nqo1
NAD(P)H quinone dehydrogenase 1
increases expression
EXP
valdecoxib results in increased expression of NQO1 mRNA
CTD
PMID:24136188
NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
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Nr1d2
nuclear receptor subfamily 1, group D, member 2
increases expression
EXP
valdecoxib results in increased expression of NR1D2 mRNA
CTD
PMID:24136188
NCBI chr15:7,524,257...7,550,553
Ensembl chr15:7,524,257...7,550,553
G
Nr3c1
nuclear receptor subfamily 3, group C, member 1
decreases expression
EXP
valdecoxib results in decreased expression of NR3C1 mRNA
CTD
PMID:24136188
NCBI chr18:31,271,681...31,393,320
Ensembl chr18:31,271,681...31,393,375
G
Nrbf2
nuclear receptor binding factor 2
decreases expression
EXP
valdecoxib results in decreased expression of NRBF2 mRNA
CTD
PMID:24136188
NCBI chr20:21,308,555...21,326,881
Ensembl chr20:21,308,576...21,326,818
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Nrep
neuronal regeneration related protein
decreases expression
EXP
valdecoxib results in decreased expression of NREP mRNA
CTD
PMID:24136188
NCBI chr18:25,017,069...25,046,593
Ensembl chr18:25,017,083...25,046,591
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Nsfl1c
NSFL1 cofactor
increases expression
EXP
valdecoxib results in increased expression of NSFL1C mRNA
CTD
PMID:24136188
NCBI chr 3:139,978,306...140,002,876
Ensembl chr 3:139,978,301...140,002,870
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Nsmce1
NSE1 homolog, SMC5-SMC6 complex component
increases expression
EXP
valdecoxib results in increased expression of NSMCE1 mRNA
CTD
PMID:24136188
NCBI chr 1:180,030,355...180,058,541
Ensembl chr 1:180,030,160...180,058,417
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Nt5dc1
5'-nucleotidase domain containing 1
increases expression
EXP
valdecoxib results in increased expression of NT5DC1 mRNA
CTD
PMID:24136188
NCBI chr20:38,105,677...38,208,613
Ensembl chr20:38,105,678...38,208,591
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Nudc
nuclear distribution C, dynein complex regulator
increases expression
EXP
valdecoxib results in increased expression of NUDC mRNA
CTD
PMID:24136188
NCBI chr 5:145,758,006...145,771,390
Ensembl chr 5:145,758,002...145,771,425
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Nupr1
nuclear protein 1, transcriptional regulator
decreases expression
EXP
valdecoxib results in decreased expression of NUPR1 mRNA
CTD
PMID:24136188
NCBI chr 1:181,213,292...181,215,327
Ensembl chr 1:181,213,368...181,215,281
G
Nusap1
nucleolar and spindle associated protein 1
decreases expression
EXP
valdecoxib results in decreased expression of NUSAP1 mRNA
CTD
PMID:24136188
NCBI chr 3:106,603,273...106,633,428
Ensembl chr 3:106,603,289...106,633,624
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Oaf
out at first homolog
decreases expression
EXP
valdecoxib results in decreased expression of OAF mRNA
CTD
PMID:24136188
NCBI chr 8:43,594,362...43,612,334
Ensembl chr 8:43,594,363...43,612,334
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Oat
ornithine aminotransferase
decreases expression
EXP
valdecoxib results in decreased expression of OAT mRNA
CTD
PMID:24136188
NCBI chr 1:187,347,862...187,367,644
Ensembl chr 1:187,347,865...187,367,682
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Odc1
ornithine decarboxylase 1
increases expression
EXP
valdecoxib results in increased expression of ODC1 mRNA
CTD
PMID:24136188
NCBI chr 6:40,329,831...40,336,444
Ensembl chr 6:40,329,964...40,336,440
G
Ogn
osteoglycin
decreases expression
EXP
valdecoxib results in decreased expression of OGN mRNA
CTD
PMID:24136188
NCBI chr17:15,032,069...15,052,626
Ensembl chr17:15,032,069...15,052,739
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Olr59
olfactory receptor 59
decreases expression
EXP
valdecoxib results in decreased expression of OLR59 mRNA
CTD
PMID:24136188
NCBI chr 1:157,193,051...157,227,707
Ensembl chr 1:157,193,080...157,211,179
G
Osbpl11
oxysterol binding protein-like 11
decreases expression
EXP
valdecoxib results in decreased expression of OSBPL11 mRNA
CTD
PMID:24136188
NCBI chr11:67,533,669...67,616,795
Ensembl chr11:67,533,672...67,596,444
G
Osgin1
oxidative stress induced growth inhibitor 1
increases expression
EXP
valdecoxib results in increased expression of OSGIN1 mRNA
CTD
PMID:24136188
NCBI chr19:47,471,750...47,500,517
Ensembl chr19:47,492,171...47,500,516
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Otc
ornithine transcarbamylase
decreases expression
EXP
valdecoxib results in decreased expression of OTC mRNA
CTD
PMID:24136188
NCBI chr X:12,453,834...12,529,954
Ensembl chr X:12,453,834...12,566,918
G
Otub2
OTU deubiquitinase, ubiquitin aldehyde binding 2
decreases expression
EXP
valdecoxib results in decreased expression of OTUB2 mRNA
CTD
PMID:24136188
NCBI chr 6:122,545,067...122,563,657
Ensembl chr 6:122,545,061...122,563,644
G
P4ha1
prolyl 4-hydroxylase subunit alpha 1
increases expression
EXP
valdecoxib results in increased expression of P4HA1 mRNA
CTD
PMID:24136188
NCBI chr20:27,302,046...27,352,098
Ensembl chr20:27,302,141...27,352,786
G
Paics
phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase
increases expression
EXP
valdecoxib results in increased expression of PAICS mRNA
CTD
PMID:24136188
NCBI chr14:31,199,086...31,232,731
Ensembl chr14:31,173,541...31,232,635
G
Parp1
poly (ADP-ribose) polymerase 1
increases expression
EXP
valdecoxib results in increased expression of PARP1 mRNA
CTD
PMID:24136188
NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
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Parvb
parvin, beta
increases expression
EXP
valdecoxib results in increased expression of PARVB mRNA
CTD
PMID:24136188
NCBI chr 7:115,360,254...115,445,767
Ensembl chr 7:115,360,261...115,445,766
G
Pc
pyruvate carboxylase
decreases expression
EXP
valdecoxib results in decreased expression of PC mRNA
CTD
PMID:24136188
NCBI chr 1:201,799,374...201,898,412
Ensembl chr 1:201,804,267...201,898,380
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Pcgf6
polycomb group ring finger 6
increases expression
EXP
valdecoxib results in increased expression of PCGF6 mRNA
CTD
PMID:24136188
NCBI chr 1:245,925,354...245,944,964
Ensembl chr 1:245,925,360...245,944,914
G
Pck1
phosphoenolpyruvate carboxykinase 1
decreases expression
EXP
valdecoxib results in decreased expression of PCK1 mRNA
CTD
PMID:24136188
NCBI chr 3:161,930,256...161,936,205
Ensembl chr 3:161,930,256...161,936,191
G
Pde4b
phosphodiesterase 4B
decreases expression
EXP
valdecoxib results in decreased expression of PDE4B mRNA
CTD
PMID:24136188
NCBI chr 5:116,799,819...117,369,155
Ensembl chr 5:116,799,971...117,367,696
G
Pdk1
pyruvate dehydrogenase kinase 1
decreases expression
EXP
valdecoxib results in decreased expression of PDK1 mRNA
CTD
PMID:24136188
NCBI chr 3:56,705,824...56,733,040
Ensembl chr 3:56,705,871...56,733,038
G
Pdk2
pyruvate dehydrogenase kinase 2
decreases expression
EXP
valdecoxib results in decreased expression of PDK2 mRNA
CTD
PMID:24136188
NCBI chr10:79,972,550...79,987,074
Ensembl chr10:79,972,556...79,987,085
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Pdp2
pyruvate dehydrogenase phosphatase catalytic subunit 2
increases expression
EXP
valdecoxib results in increased expression of PDP2 mRNA
CTD
PMID:24136188
NCBI chr19:386,408...394,068
Ensembl chr19:386,406...394,074
G
Pelo
pelota mRNA surveillance and ribosome rescue factor
increases expression
EXP
valdecoxib results in increased expression of PELO mRNA
CTD
PMID:24136188
NCBI chr 2:46,797,853...46,799,621
Ensembl chr 2:46,797,853...46,799,746
G
Per1
period circadian regulator 1
decreases expression
EXP
valdecoxib results in decreased expression of PER1 mRNA
CTD
PMID:24136188
NCBI chr10:53,800,126...53,814,963
Ensembl chr10:53,805,535...53,814,431
G
Per2
period circadian regulator 2
decreases expression
EXP
valdecoxib results in decreased expression of PER2 mRNA
CTD
PMID:24136188
NCBI chr 9:92,007,289...92,049,551
Ensembl chr 9:92,007,296...92,049,459
G
Pfdn2
prefoldin subunit 2
increases expression
EXP
valdecoxib results in increased expression of PFDN2 mRNA
CTD
PMID:24136188
NCBI chr13:83,772,301...83,791,367
Ensembl chr13:83,753,877...83,790,504
G
Pfkfb1
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
decreases expression
EXP
valdecoxib results in decreased expression of PFKFB1 mRNA
CTD
PMID:24136188
NCBI chr X:19,508,522...19,562,165
Ensembl chr X:19,508,546...19,562,182
G
Pgrmc2
progesterone receptor membrane component 2
decreases expression
EXP
valdecoxib results in decreased expression of PGRMC2 mRNA
CTD
PMID:24136188
NCBI chr 2:124,068,257...124,084,155
Ensembl chr 2:124,068,260...124,084,155
G
Phgdh
phosphoglycerate dehydrogenase
increases expression
EXP
valdecoxib results in increased expression of PHGDH mRNA
CTD
PMID:24136188
NCBI chr 2:185,906,962...185,936,054
Ensembl chr 2:185,906,966...185,935,944
G
Phlda2
pleckstrin homology-like domain, family A, member 2
increases expression
EXP
valdecoxib results in increased expression of PHLDA2 mRNA
CTD
PMID:24136188
NCBI chr 1:198,696,897...198,699,292
Ensembl chr 1:198,696,897...198,697,836
G
Phlda3
pleckstrin homology-like domain, family A, member 3
decreases expression
EXP
valdecoxib results in decreased expression of PHLDA3 mRNA
CTD
PMID:24136188
NCBI chr13:47,193,250...47,196,335
Ensembl chr13:47,193,086...47,196,335
G
Phtf1
putative homeodomain transcription factor 1
decreases expression
EXP
valdecoxib results in decreased expression of PHTF1 mRNA
CTD
PMID:24136188
NCBI chr 2:191,470,849...191,537,399
Ensembl chr 2:191,473,130...191,512,078
G
Phyh
phytanoyl-CoA 2-hydroxylase
decreases expression
EXP
valdecoxib results in decreased expression of PHYH mRNA
CTD
PMID:24136188
NCBI chr17:73,329,461...73,346,359
Ensembl chr17:73,329,082...73,346,409
G
Pi4k2b
phosphatidylinositol 4-kinase type 2 beta
increases expression
EXP
valdecoxib results in increased expression of PI4K2B mRNA
CTD
PMID:24136188
NCBI chr14:58,221,790...58,248,716
Ensembl chr14:58,220,437...58,248,673
G
Pigp
phosphatidylinositol glycan anchor biosynthesis, class P
decreases expression
EXP
valdecoxib results in decreased expression of PIGP mRNA
CTD
PMID:24136188
NCBI chr11:33,682,943...33,689,111
Ensembl chr11:33,682,948...33,689,321
G
Pik3c2g
phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 gamma
decreases expression
EXP
valdecoxib results in decreased expression of PIK3C2G mRNA
CTD
PMID:24136188
NCBI chr 4:172,483,752...172,851,623
Ensembl chr 4:172,484,345...172,850,544
G
Pir
pirin
increases expression
EXP
valdecoxib results in increased expression of PIR mRNA
CTD
PMID:24136188
NCBI chr X:30,108,536...30,219,269
Ensembl chr X:30,108,538...30,219,218
G
Pisd
phosphatidylserine decarboxylase
increases expression
EXP
valdecoxib results in increased expression of PISD mRNA
CTD
PMID:24136188
NCBI chr14:77,941,927...77,991,021
Ensembl chr14:77,941,948...77,991,003
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Pkdcc
protein kinase domain containing, cytoplasmic
decreases expression
EXP
valdecoxib results in decreased expression of PKDCC mRNA
CTD
PMID:24136188
NCBI chr 6:11,455,686...11,465,002
Ensembl chr 6:11,455,686...11,465,556
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Pklr
pyruvate kinase L/R
decreases expression
EXP
valdecoxib results in decreased expression of PKLR mRNA
CTD
PMID:24136188
NCBI chr 2:174,543,008...174,551,863
Ensembl chr 2:174,543,039...174,551,870
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Pla2g12a
phospholipase A2, group XIIA
increases expression
EXP
valdecoxib results in increased expression of PLA2G12A mRNA
CTD
PMID:24136188
NCBI chr 2:218,436,497...218,452,742
Ensembl chr 2:218,436,513...218,452,740
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Plaa
phospholipase A2, activating protein
increases expression
EXP
valdecoxib results in increased expression of PLAA mRNA
CTD
PMID:24136188
NCBI chr 5:109,428,600...109,460,373
Ensembl chr 5:109,428,265...109,460,282
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Pld1
phospholipase D1
decreases expression
EXP
valdecoxib results in decreased expression of PLD1 mRNA
CTD
PMID:24136188
NCBI chr 2:110,849,205...111,047,304
Ensembl chr 2:110,893,608...111,047,692
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Plekha5
pleckstrin homology domain containing A5
increases expression
EXP
valdecoxib results in increased expression of PLEKHA5 mRNA
CTD
PMID:24136188
NCBI chr 4:173,333,891...173,503,546
Ensembl chr 4:173,334,055...173,503,546
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Plpp2
phospholipid phosphatase 2
increases expression
EXP
valdecoxib results in increased expression of PLPP2 mRNA
CTD
PMID:24136188
NCBI chr 7:10,175,918...10,184,032
Ensembl chr 7:10,175,948...10,184,071
G
Plpp3
phospholipid phosphatase 3
decreases expression
EXP
valdecoxib results in decreased expression of PLPP3 mRNA
CTD
PMID:24136188
NCBI chr 5:119,927,085...120,002,206
Ensembl chr 5:119,927,085...120,002,205
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Pls3
plastin 3
increases expression
EXP
valdecoxib results in increased expression of PLS3 mRNA
CTD
PMID:24136188
NCBI chr X:111,589,193...111,683,908
Ensembl chr X:111,589,254...111,683,891
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Plxna2
plexin A2
decreases expression
EXP
valdecoxib results in decreased expression of PLXNA2 mRNA
CTD
PMID:24136188
NCBI chr13:106,163,103...106,358,979
Ensembl chr13:106,163,103...106,358,979
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Pmm1
phosphomannomutase 1
increases expression
EXP
valdecoxib results in increased expression of PMM1 mRNA
CTD
PMID:24136188
NCBI chr 7:113,466,632...113,477,004
Ensembl chr 7:113,466,632...113,477,022
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Pno1
partner of NOB1 homolog
increases expression
EXP
valdecoxib results in increased expression of PNO1 mRNA
CTD
PMID:24136188
NCBI chr14:91,609,711...91,618,280
Ensembl chr14:91,609,233...91,618,324
G
Pnpla3
patatin-like phospholipase domain containing 3
decreases expression
EXP
valdecoxib results in decreased expression of PNPLA3 mRNA
CTD
PMID:24136188
NCBI chr 7:115,293,538...115,314,077
Ensembl chr 7:115,293,538...115,314,077
G
Pnpla7
patatin-like phospholipase domain containing 7
increases expression
EXP
valdecoxib results in increased expression of PNPLA7 mRNA
CTD
PMID:24136188
NCBI chr 3:7,782,572...7,861,504
Ensembl chr 3:7,782,572...7,861,497
G
Polr3g
RNA polymerase III subunit G
increases expression
EXP
valdecoxib results in increased expression of POLR3G mRNA
CTD
PMID:24136188
NCBI chr 2:11,945,215...11,986,125
Ensembl chr 2:11,945,217...11,986,125
G
Por
cytochrome p450 oxidoreductase
increases expression
EXP
valdecoxib results in increased expression of POR mRNA
CTD
PMID:24136188
NCBI chr12:20,951,058...20,999,198
Ensembl chr12:20,951,058...20,999,245
G
Ppid
peptidylprolyl isomerase D
increases expression
EXP
valdecoxib results in increased expression of PPID mRNA
CTD
PMID:24136188
NCBI chr 2:164,727,803...164,740,168
Ensembl chr 2:164,727,779...164,740,221
G
Ppp1r14b
protein phosphatase 1, regulatory (inhibitor) subunit 14B
increases expression
EXP
valdecoxib results in increased expression of PPP1R14B mRNA
CTD
PMID:24136188
NCBI chr 1:204,165,210...204,167,320
Ensembl chr 1:204,163,299...204,167,319 Ensembl chr12:204,163,299...204,167,319
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Ppp1r3b
protein phosphatase 1, regulatory subunit 3B
decreases expression
EXP
valdecoxib results in decreased expression of PPP1R3B mRNA
CTD
PMID:24136188
NCBI chr16:56,830,011...56,842,395
Ensembl chr16:56,829,660...56,842,406
G
Ppp2r1b
protein phosphatase 2 scaffold subunit A beta
increases expression
EXP
valdecoxib results in increased expression of PPP2R1B mRNA
CTD
PMID:24136188
NCBI chr 8:51,195,860...51,228,442
Ensembl chr 8:51,186,717...51,228,485
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Ppp2r5e
protein phosphatase 2 regulatory subunit B', epsilon
decreases expression
EXP
valdecoxib results in decreased expression of PPP2R5E mRNA
CTD
PMID:24136188
NCBI chr 6:94,168,846...94,317,872
Ensembl chr 6:94,168,846...94,317,872
G
Prcp
prolylcarboxypeptidase
decreases expression
EXP
valdecoxib results in decreased expression of PRCP mRNA
CTD
PMID:24136188
NCBI chr 1:146,931,487...146,983,891
Ensembl chr 1:146,930,561...146,984,530
G
Prodh
proline dehydrogenase
decreases expression
EXP
valdecoxib results in decreased expression of PRODH mRNA
CTD
PMID:24136188
NCBI chr11:82,910,043...82,927,305
Ensembl chr11:82,910,137...82,927,305
G
Prpf19
pre-mRNA processing factor 19
increases expression
EXP
valdecoxib results in increased expression of PRPF19 mRNA
CTD
PMID:24136188
NCBI chr 1:207,541,582...207,552,664
Ensembl chr 1:207,541,595...207,552,662
G
Prps1
phosphoribosyl pyrophosphate synthetase 1
increases expression
EXP
valdecoxib results in increased expression of PRPS1 mRNA
CTD
PMID:24136188
NCBI chr X:104,132,139...104,154,191
Ensembl chr X:104,132,141...104,154,187
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Psip1
PC4 and SRSF1 interacting protein 1
increases expression
EXP
valdecoxib results in increased expression of PSIP1 mRNA
CTD
PMID:24136188
NCBI chr 5:97,847,010...97,879,280
Ensembl chr 5:97,847,015...97,879,257
G
Psma1
proteasome 20S subunit alpha 1
increases expression
EXP
valdecoxib results in increased expression of PSMA1 mRNA
CTD
PMID:24136188
NCBI chr 1:168,442,421...168,453,440
Ensembl chr 1:168,440,936...168,453,472
G
Psma2
proteasome 20S subunit alpha 2
increases expression
EXP
valdecoxib results in increased expression of PSMA2 mRNA
CTD
PMID:24136188
NCBI chr17:50,554,536...50,564,923
Ensembl chr17:50,551,924...50,564,938
G
Psma3
proteasome 20S subunit alpha 3
increases expression
EXP
valdecoxib results in increased expression of PSMA3 mRNA
CTD
PMID:24136188
NCBI chr 6:89,483,741...89,503,775
Ensembl chr 6:89,483,727...89,504,965
G
Psma4
proteasome 20S subunit alpha 4
increases expression
EXP
valdecoxib results in increased expression of PSMA4 mRNA
CTD
PMID:24136188
NCBI chr 8:55,340,431...55,347,893
Ensembl chr 8:55,340,386...55,347,890
G
Psma5
proteasome 20S subunit alpha 5
increases expression
EXP
valdecoxib results in increased expression of PSMA5 mRNA
CTD
PMID:24136188
NCBI chr 2:195,896,369...195,919,733
Ensembl chr 2:195,896,365...195,919,731
G
Psma6
proteasome 20S subunit alpha 6
increases expression
EXP
valdecoxib results in increased expression of PSMA6 mRNA
CTD
PMID:24136188
NCBI chr 6:72,765,534...72,796,554
Ensembl chr 6:72,765,473...72,796,554
G
Psma7
proteasome 20S subunit alpha 7
increases expression
EXP
valdecoxib results in increased expression of PSMA7 mRNA
CTD
PMID:24136188
NCBI chr 3:167,137,279...167,143,626
Ensembl chr 3:167,137,263...167,143,672
G
Psmb1
proteasome 20S subunit beta 1
increases expression
EXP
valdecoxib results in increased expression of PSMB1 mRNA
CTD
PMID:24136188
NCBI chr 1:56,442,432...56,463,544
Ensembl chr 1:56,420,618...56,463,560
G
Psmb10
proteasome 20S subunit beta 10
increases expression
EXP
valdecoxib results in increased expression of PSMB10 mRNA
CTD
PMID:24136188
NCBI chr19:33,830,958...33,833,442
Ensembl chr19:33,827,229...33,833,626
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Psmb2
proteasome 20S subunit beta 2
increases expression
EXP
valdecoxib results in increased expression of PSMB2 mRNA
CTD
PMID:24136188
NCBI chr 5:138,970,564...139,002,715
Ensembl chr 5:138,970,533...139,021,137
G
Psmb3
proteasome 20S subunit beta 3
increases expression
EXP
valdecoxib results in increased expression of PSMB3 mRNA
CTD
PMID:24136188
NCBI chr10:82,697,425...82,704,521
Ensembl chr10:82,697,425...82,704,521
G
Psmb4
proteasome 20S subunit beta 4
increases expression
EXP
valdecoxib results in increased expression of PSMB4 mRNA
CTD
PMID:24136188
NCBI chr 2:182,442,757...182,445,532
Ensembl chr 2:182,442,756...182,445,746
G
Psmb5
proteasome 20S subunit beta 5
increases expression
EXP
valdecoxib results in increased expression of PSMB5 mRNA
CTD
PMID:24136188
NCBI chr15:28,072,772...28,077,367
Ensembl chr15:28,072,781...28,077,440
G
Psmb6
proteasome 20S subunit beta 6
increases expression
EXP
valdecoxib results in increased expression of PSMB6 mRNA
CTD
PMID:24136188
NCBI chr10:55,239,256...55,241,586
Ensembl chr10:55,239,241...55,241,586
G
Psmb7
proteasome 20S subunit beta 7
increases expression
EXP
valdecoxib results in increased expression of PSMB7 mRNA
CTD
PMID:24136188
NCBI chr 3:22,357,777...22,417,748
Ensembl chr 3:22,354,698...22,417,937
G
Psmc1
proteasome 26S subunit, ATPase 1
increases expression
EXP
valdecoxib results in increased expression of PSMC1 mRNA
CTD
PMID:24136188
NCBI chr 6:119,392,833...119,405,233
Ensembl chr 6:119,392,855...119,410,123
G
Psmc2
proteasome 26S subunit, ATPase 2
increases expression
EXP
valdecoxib results in increased expression of PSMC2 mRNA
CTD
PMID:24136188
NCBI chr 4:13,255,850...13,270,160
Ensembl chr 4:13,255,856...13,270,185
G
Psmc3
proteasome 26S subunit, ATPase 3
increases expression
EXP
valdecoxib results in increased expression of PSMC3 mRNA
CTD
PMID:24136188
NCBI chr 3:77,031,825...77,037,207
Ensembl chr 3:77,031,825...77,043,358
G
Psmc4
proteasome 26S subunit, ATPase 4
increases expression
EXP
valdecoxib results in increased expression of PSMC4 mRNA
CTD
PMID:24136188
NCBI chr 1:83,349,127...83,357,497
Ensembl chr 1:83,348,592...83,357,494
G
Psmc5
proteasome 26S subunit, ATPase 5
increases expression
EXP
valdecoxib results in increased expression of PSMC5 mRNA
CTD
PMID:24136188
NCBI chr10:91,187,763...91,193,697
Ensembl chr10:91,187,743...91,213,135
G
Psmc6
proteasome 26S subunit, ATPase 6
increases expression
EXP
valdecoxib results in increased expression of PSMC6 mRNA
CTD
PMID:24136188
NCBI chr15:18,542,585...18,564,057
Ensembl chr15:18,542,563...18,564,055
G
Psmd1
proteasome 26S subunit, non-ATPase 1
increases expression
EXP
valdecoxib results in increased expression of PSMD1 mRNA
CTD
PMID:24136188
NCBI chr 9:86,709,714...86,785,213
Ensembl chr 9:86,709,947...86,785,211
G
Psmd11
proteasome 26S subunit, non-ATPase 11
increases expression
EXP
valdecoxib results in increased expression of PSMD11 mRNA
CTD
PMID:24136188
NCBI chr10:65,433,853...65,479,774
Ensembl chr10:65,433,853...65,479,766
G
Psmd12
proteasome 26S subunit, non-ATPase 12
increases expression
EXP
valdecoxib results in increased expression of PSMD12 mRNA
CTD
PMID:24136188
NCBI chr10:92,438,223...92,457,323
Ensembl chr10:92,438,298...92,457,287
G
Psmd13
proteasome 26S subunit, non-ATPase 13
increases expression
EXP
valdecoxib results in increased expression of PSMD13 mRNA
CTD
PMID:24136188
NCBI chr 1:195,964,617...195,976,895
Ensembl chr 1:195,964,138...195,976,905
G
Psmd14
proteasome 26S subunit, non-ATPase 14
increases expression
EXP
valdecoxib results in increased expression of PSMD14 mRNA
CTD
PMID:24136188
NCBI chr 3:46,254,338...46,347,076
Ensembl chr 3:46,254,330...46,347,076
G
Psmd2
proteasome 26S subunit ubiquitin receptor, non-ATPase 2
increases expression
EXP
valdecoxib results in increased expression of PSMD2 mRNA
CTD
PMID:24136188
NCBI chr11:80,248,364...80,258,991
Ensembl chr11:80,248,364...80,259,043
G
Psmd3
proteasome 26S subunit, non-ATPase 3
increases expression
EXP
valdecoxib results in increased expression of PSMD3 mRNA
CTD
PMID:24136188
NCBI chr10:83,643,473...83,655,620
Ensembl chr10:83,643,647...83,655,618
G
Psmd4
proteasome 26S subunit ubiquitin receptor, non-ATPase 4
increases expression
EXP
valdecoxib results in increased expression of PSMD4 mRNA
CTD
PMID:24136188
NCBI chr 2:182,598,934...182,608,250
Ensembl chr 2:182,598,934...182,608,194
G
Psmd5
proteasome 26S subunit, non-ATPase 5
increases expression
EXP
valdecoxib results in increased expression of PSMD5 mRNA
CTD
PMID:24136188
NCBI chr 3:18,133,715...18,151,000
Ensembl chr 3:18,133,717...18,151,029
G
Psmd6
proteasome 26S subunit, non-ATPase 6
increases expression
EXP
valdecoxib results in increased expression of PSMD6 mRNA
CTD
PMID:24136188
NCBI chr15:11,102,174...11,112,180
Ensembl chr15:11,102,180...11,205,620
G
Psmd7
proteasome 26S subunit, non-ATPase 7
increases expression
EXP
valdecoxib results in increased expression of PSMD7 mRNA
CTD
PMID:24136188
NCBI chr19:35,494,317...35,501,605
Ensembl chr19:35,494,316...35,501,588
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Psmd8
proteasome 26S subunit, non-ATPase 8
increases expression
EXP
valdecoxib results in increased expression of PSMD8 mRNA
CTD
PMID:24136188
NCBI chr 1:84,474,377...84,481,209
Ensembl chr 1:84,474,378...84,481,209
G
Psme4
proteasome activator subunit 4
increases expression
EXP
valdecoxib results in increased expression of PSME4 mRNA
CTD
PMID:24136188
NCBI chr14:104,505,716...104,609,410
Ensembl chr14:104,505,716...104,609,408
G
Ptdss2
phosphatidylserine synthase 2
increases expression
EXP
valdecoxib results in increased expression of PTDSS2 mRNA
CTD
PMID:24136188
NCBI chr 1:196,241,439...196,267,632
Ensembl chr 1:196,241,494...196,267,685
G
Ptges3
prostaglandin E synthase 3
increases expression
EXP
valdecoxib results in increased expression of PTGES3 mRNA
CTD
PMID:24136188
NCBI chr 7:490,698...507,759
Ensembl chr 7:490,656...508,084
G
Ptgis
prostaglandin I2 synthase
decreases expression
EXP
valdecoxib results in decreased expression of PTGIS mRNA
CTD
PMID:24136188
NCBI chr 3:155,928,564...155,964,228
Ensembl chr 3:155,916,412...155,965,451
G
Ptgr1
prostaglandin reductase 1
decreases expression
EXP
valdecoxib results in decreased expression of PTGR1 mRNA
CTD
PMID:24136188
NCBI chr 5:73,784,000...73,802,624
Ensembl chr 5:73,784,009...73,802,666
G
Ptgs2
prostaglandin-endoperoxide synthase 2
decreases activity
ISO
valdecoxib results in decreased activity of PTGS2 protein
CTD
PMID:15887009 PMID:17164136
NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
G
Ptpn21
protein tyrosine phosphatase, non-receptor type 21
increases expression
EXP
valdecoxib results in increased expression of PTPN21 mRNA
CTD
PMID:24136188
NCBI chr 6:117,933,066...117,998,095
Ensembl chr 6:117,933,066...117,998,095
G
Ptprd
protein tyrosine phosphatase, receptor type, D
decreases expression
EXP
valdecoxib results in decreased expression of PTPRD mRNA
CTD
PMID:24136188
NCBI chr 5:90,046,993...90,698,977 NCBI chr 5:91,122,354...91,641,754
Ensembl chr 5:90,048,966...92,369,396
G
Ptprn
protein tyrosine phosphatase, receptor type, N
decreases expression
EXP
valdecoxib results in decreased expression of PTPRN mRNA
CTD
PMID:24136188
NCBI chr 9:76,741,010...76,756,704
Ensembl chr 9:76,741,016...76,756,190
G
Pttg1
PTTG1 regulator of sister chromatid separation, securin
decreases expression
EXP
valdecoxib results in decreased expression of PTTG1 mRNA
CTD
PMID:24136188
NCBI chr10:27,893,466...27,904,965
Ensembl chr10:27,893,689...27,904,837
G
Pygl
glycogen phosphorylase L
decreases expression
EXP
valdecoxib results in decreased expression of PYGL mRNA
CTD
PMID:24136188
NCBI chr 6:88,697,598...88,740,260
Ensembl chr 6:88,697,593...88,740,310
G
Pyroxd2
pyridine nucleotide-disulphide oxidoreductase domain 2
decreases expression
EXP
valdecoxib results in decreased expression of PYROXD2 mRNA
CTD
PMID:24136188
NCBI chr 1:241,523,278...241,549,083
Ensembl chr 1:241,523,377...241,548,761
G
Qprt
quinolinate phosphoribosyltransferase
decreases expression
EXP
valdecoxib results in decreased expression of QPRT mRNA
CTD
PMID:24136188
NCBI chr 1:181,718,189...181,733,486
Ensembl chr 1:181,718,190...181,733,486
G
R3hdm2
R3H domain containing 2
decreases expression
EXP
valdecoxib results in decreased expression of R3HDM2 mRNA
CTD
PMID:24136188
NCBI chr 7:63,212,519...63,340,574
Ensembl chr 7:63,232,346...63,340,540
G
Rab30
RAB30, member RAS oncogene family
increases expression
EXP
valdecoxib results in increased expression of RAB30 mRNA
CTD
PMID:24136188
NCBI chr 1:146,803,719...146,898,369
Ensembl chr 1:146,803,714...146,892,181
G
Rab40b
Rab40b, member RAS oncogene family
decreases expression
EXP
valdecoxib results in decreased expression of RAB40B mRNA
CTD
PMID:24136188
NCBI chr10:106,631,514...106,659,090
Ensembl chr10:106,631,514...106,659,090
G
Rab5if
RAB5 interacting factor
increases expression
EXP
valdecoxib results in increased expression of RAB5IF mRNA
CTD
PMID:24136188
NCBI chr 3:145,357,990...145,368,012
Ensembl chr 3:145,357,861...145,368,012
G
Rad23b
RAD23 homolog B, nucleotide excision repair protein
increases expression
EXP
valdecoxib results in increased expression of RAD23B mRNA
CTD
PMID:24136188
NCBI chr 5:70,090,232...70,128,340
Ensembl chr 5:70,090,232...70,128,319
G
Ran
RAN, member RAS oncogene family
increases expression
EXP
valdecoxib results in increased expression of RAN mRNA
CTD
PMID:24136188
NCBI chr12:27,674,049...27,678,598
Ensembl chr12:27,674,050...27,678,276
G
Rangrf
RAN guanine nucleotide release factor
increases expression
EXP
valdecoxib results in increased expression of RANGRF mRNA
CTD
PMID:24136188
NCBI chr10:53,677,467...53,678,880
Ensembl chr10:53,677,467...53,678,840
G
Rapgef4
Rap guanine nucleotide exchange factor 4
increases expression
EXP
valdecoxib results in increased expression of RAPGEF4 mRNA
CTD
PMID:24136188
NCBI chr 3:56,809,388...57,101,332
Ensembl chr 3:56,809,270...57,102,316
G
Raph1
Ras association (RalGDS/AF-6) and pleckstrin homology domains 1
increases expression
EXP
valdecoxib results in increased expression of RAPH1 mRNA
CTD
PMID:24136188
NCBI chr 9:61,907,476...61,990,170
Ensembl chr 9:61,907,758...61,961,209
G
Rarb
retinoic acid receptor, beta
decreases expression
EXP
valdecoxib results in decreased expression of RARB mRNA
CTD
PMID:24136188
NCBI chr15:8,700,533...9,051,288
Ensembl chr15:8,406,492...9,051,288
G
Rb1
RB transcriptional corepressor 1
decreases expression
EXP
valdecoxib results in decreased expression of RB1 mRNA
CTD
PMID:24136188
NCBI chr15:48,371,295...48,502,473
Ensembl chr15:48,371,296...48,502,302
G
Rb1cc1
RB1-inducible coiled-coil 1
increases expression
EXP
valdecoxib results in increased expression of RB1CC1 mRNA
CTD
PMID:24136188
NCBI chr 5:13,161,648...13,225,560
Ensembl chr 5:13,161,648...13,225,560
G
Rbbp6
RB binding protein 6, ubiquitin ligase
increases expression
EXP
valdecoxib results in increased expression of RBBP6 mRNA
CTD
PMID:24136188
NCBI chr 1:177,503,988...177,537,397
Ensembl chr 1:177,503,313...177,535,678
G
Rbbp8
RB binding protein 8, endonuclease
increases expression
EXP
valdecoxib results in increased expression of RBBP8 mRNA
CTD
PMID:24136188
NCBI chr18:2,922,985...2,988,851
Ensembl chr18:2,921,286...2,988,846
G
Rbis
ribosomal biogenesis factor
increases expression
EXP
valdecoxib results in increased expression of RBIS mRNA
CTD
PMID:24136188
NCBI chr 2:86,981,314...86,997,352
Ensembl chr 2:86,991,315...87,041,339
G
Rbm5
RNA binding motif protein 5
increases expression
EXP
valdecoxib results in increased expression of RBM5 mRNA
CTD
PMID:24136188
NCBI chr 8:108,420,220...108,449,481
Ensembl chr 8:108,420,222...108,449,430
G
Rbp1
retinol binding protein 1
decreases expression
EXP
valdecoxib results in decreased expression of RBP1 mRNA
CTD
PMID:24136188
NCBI chr 8:99,025,218...99,046,740
Ensembl chr 8:99,025,206...99,046,743
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Rbpms
RNA binding protein, mRNA processing factor
increases expression
EXP
valdecoxib results in increased expression of RBPMS mRNA
CTD
PMID:24136188
NCBI chr16:58,239,370...58,395,424
Ensembl chr16:58,239,474...58,395,426
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Rbx1
ring-box 1
increases expression
EXP
valdecoxib results in increased expression of RBX1 mRNA
CTD
PMID:24136188
NCBI chr 7:112,976,863...113,001,051
Ensembl chr 7:112,990,835...113,001,051
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Rcan1
regulator of calcineurin 1
decreases expression
EXP
valdecoxib results in decreased expression of RCAN1 mRNA
CTD
PMID:24136188
NCBI chr11:31,622,208...31,702,150
Ensembl chr11:31,622,210...31,702,045
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Rdh5
retinol dehydrogenase 5
decreases expression
EXP
valdecoxib results in decreased expression of RDH5 mRNA
CTD
PMID:24136188
NCBI chr 7:1,341,172...1,346,863
Ensembl chr 7:1,340,934...1,351,558
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Rell1
RELT-like 1
increases expression
EXP
valdecoxib results in increased expression of RELL1 mRNA
CTD
PMID:24136188
NCBI chr14:44,318,640...44,378,541
Ensembl chr14:44,303,009...44,378,500
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Rex1bd
required for excision 1-B domain containing
increases expression
EXP
valdecoxib results in increased expression of REX1BD mRNA
CTD
PMID:24136188
NCBI chr16:18,922,050...18,924,521
Ensembl chr16:18,922,037...18,924,526
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Rexo2
RNA exonuclease 2
increases expression
EXP
valdecoxib results in increased expression of REXO2 mRNA
CTD
PMID:24136188
NCBI chr 8:48,811,900...48,823,622
Ensembl chr 8:48,811,900...48,823,622
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Rfc2
replication factor C subunit 2
increases expression
EXP
valdecoxib results in increased expression of RFC2 mRNA
CTD
PMID:24136188
NCBI chr12:22,120,449...22,133,576
Ensembl chr12:22,120,010...22,133,557
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Rgn
regucalcin
decreases expression
EXP
valdecoxib results in decreased expression of RGN mRNA
CTD
PMID:24136188
NCBI chr X:1,619,030...1,634,456
Ensembl chr X:1,619,032...1,634,450
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Rhpn2
rhophilin, Rho GTPase binding protein 2
increases expression
EXP
valdecoxib results in increased expression of RHPN2 mRNA
CTD
PMID:24136188
NCBI chr 1:87,991,143...88,051,895
Ensembl chr 1:87,991,144...88,051,902
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Rmdn2
regulator of microtubule dynamics 2
decreases expression
EXP
valdecoxib results in decreased expression of RMDN2 mRNA
CTD
PMID:24136188
NCBI chr 6:15,372,569...15,443,000
Ensembl chr 6:15,375,496...15,441,480
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Rnase4
ribonuclease A family member 4
decreases expression
EXP
valdecoxib results in decreased expression of RNASE4 mRNA
CTD
PMID:24136188
NCBI chr15:24,312,765...24,330,112
Ensembl chr15:24,312,464...24,330,117
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Rorc
RAR-related orphan receptor C
decreases expression
EXP
valdecoxib results in decreased expression of RORC mRNA
CTD
PMID:24136188
NCBI chr 2:182,009,707...182,034,910
Ensembl chr 2:182,009,286...182,034,907
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Rpa1
replication protein A1
decreases expression
EXP
valdecoxib results in decreased expression of RPA1 mRNA
CTD
PMID:24136188
NCBI chr10:60,148,869...60,199,970
Ensembl chr10:60,148,793...60,199,949
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Rprm
reprimo, TP53 dependent G2 arrest mediator homolog
decreases expression
EXP
valdecoxib results in decreased expression of RPRM mRNA
CTD
PMID:24136188
NCBI chr 3:38,539,581...38,540,998
Ensembl chr 3:38,539,581...38,540,998
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Rrm2
ribonucleotide reductase regulatory subunit M2
decreases expression
EXP
valdecoxib results in decreased expression of RRM2 mRNA
CTD
PMID:24136188
NCBI chr 6:41,339,858...41,346,774
Ensembl chr 6:41,340,557...41,346,773
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RT1-DMa
RT1 class II, locus DMa
affects expression
ISO
valdecoxib affects the expression of HLA-DMA mRNA
CTD
PMID:25811541
NCBI chr20:4,707,028...4,710,432
Ensembl chr20:4,707,028...4,710,432
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RT1-DMb
RT1 class II, locus DMb
affects expression
ISO
valdecoxib affects the expression of HLA-DMB mRNA
CTD
PMID:25811541
NCBI chr20:4,693,102...4,700,340
Ensembl chr20:4,693,103...4,700,340
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RT1-Ha
RT1 class II, locus Ha
affects expression
ISO
valdecoxib affects the expression of HLA-DPA1 mRNA
CTD
PMID:25811541
NCBI chr20:4,760,631...4,770,662
Ensembl chr20:4,760,118...4,770,244
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S1pr1
sphingosine-1-phosphate receptor 1
decreases expression
EXP
valdecoxib results in decreased expression of S1PR1 mRNA
CTD
PMID:24136188
NCBI chr 2:203,624,752...203,629,110
Ensembl chr 2:203,621,587...203,629,681
G
Samd11
sterile alpha motif domain containing 11
decreases expression
EXP
valdecoxib results in decreased expression of SAMD11 mRNA
CTD
PMID:24136188
NCBI chr 5:166,831,681...166,859,805
Ensembl chr 5:166,831,663...166,850,009
G
Sardh
sarcosine dehydrogenase
decreases expression
EXP
valdecoxib results in decreased expression of SARDH mRNA
CTD
PMID:24136188
NCBI chr 3:10,510,553...10,575,342
Ensembl chr 3:10,510,553...10,573,874
G
Sbno1
strawberry notch homolog 1
increases expression
EXP
valdecoxib results in increased expression of SBNO1 mRNA
CTD
PMID:24136188
NCBI chr12:32,175,176...32,234,200
Ensembl chr12:32,185,485...32,230,158
G
Sbno2
strawberry notch homolog 2
increases expression
EXP
valdecoxib results in increased expression of SBNO2 mRNA
CTD
PMID:24136188
NCBI chr 7:9,605,572...9,649,529
Ensembl chr 7:9,605,627...9,649,527
G
Sc5d
sterol-C5-desaturase
increases expression
EXP
valdecoxib results in increased expression of SC5D mRNA
CTD
PMID:24136188
NCBI chr 8:42,629,649...42,641,257
Ensembl chr 8:42,632,672...42,641,273
G
Scarb2
scavenger receptor class B, member 2
increases expression
EXP
valdecoxib results in increased expression of SCARB2 mRNA
CTD
PMID:24136188
NCBI chr14:15,558,271...15,609,813
Ensembl chr14:15,558,236...15,609,813
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Scd
stearoyl-CoA desaturase
decreases expression
EXP
valdecoxib results in decreased expression of SCD1 mRNA
CTD
PMID:24136188
NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562
G
Scn1b
sodium voltage-gated channel beta subunit 1
increases expression
EXP
valdecoxib results in increased expression of SCN1B mRNA
CTD
PMID:24136188
NCBI chr 1:86,353,917...86,363,820
Ensembl chr 1:86,353,917...86,363,739
G
Sds
serine dehydratase
decreases expression
EXP
valdecoxib results in decreased expression of SDS mRNA
CTD
PMID:24136188
NCBI chr12:36,083,226...36,090,540
Ensembl chr12:36,083,229...36,088,203
G
Sdsl
serine dehydratase-like
decreases expression
EXP
valdecoxib results in decreased expression of SDSL mRNA
CTD
PMID:24136188
NCBI chr12:36,099,693...36,109,914
Ensembl chr12:36,099,693...36,109,906
G
Sephs1
selenophosphate synthetase 1
increases expression
EXP
valdecoxib results in increased expression of SEPHS1 mRNA
CTD
PMID:24136188
NCBI chr17:73,354,435...73,382,803
Ensembl chr17:73,356,530...73,382,593
G
Serpinf1
serpin family F member 1
decreases expression
EXP
valdecoxib results in decreased expression of SERPINF1 mRNA
CTD
PMID:24136188
NCBI chr10:60,250,198...60,262,593
Ensembl chr10:60,249,708...60,262,646
G
Sertad3
SERTA domain containing 3
increases expression
EXP
valdecoxib results in increased expression of SERTAD3 mRNA
CTD
PMID:24136188
NCBI chr 1:82,763,535...82,767,271
Ensembl chr 1:82,763,149...82,769,001
G
Sesn1
sestrin 1
decreases expression
EXP
valdecoxib results in decreased expression of SESN1 mRNA
CTD
PMID:24136188
NCBI chr20:45,294,876...45,387,698
Ensembl chr20:45,294,871...45,387,697
G
Sesn2
sestrin 2
decreases expression
EXP
valdecoxib results in decreased expression of SESN2 mRNA
CTD
PMID:24136188
NCBI chr 5:144,702,287...144,721,241
Ensembl chr 5:144,701,530...144,721,260
G
Setd4
SET domain containing 4
increases expression
EXP
valdecoxib results in increased expression of SETD4 mRNA
CTD
PMID:24136188
NCBI chr11:32,829,509...32,859,162
Ensembl chr11:32,838,063...32,858,243
G
Sez6
seizure related 6 homolog
decreases expression
EXP
valdecoxib results in decreased expression of SEZ6 mRNA
CTD
PMID:24136188
NCBI chr10:62,818,931...62,868,686
Ensembl chr10:62,819,069...62,868,671
G
Sfmbt1
Scm-like with four mbt domains 1
increases expression
EXP
valdecoxib results in increased expression of SFMBT1 mRNA
CTD
PMID:24136188
NCBI chr16:5,889,046...6,009,860
Ensembl chr16:5,890,782...6,006,605
G
Sgf29
SAGA complex associated factor 29
increases expression
EXP
valdecoxib results in increased expression of SGF29 mRNA
CTD
PMID:24136188
NCBI chr 1:181,238,458...181,271,931
Ensembl chr 1:181,238,468...181,274,781
G
Sgpl1
sphingosine-1-phosphate lyase 1
increases expression
EXP
valdecoxib results in increased expression of SGPL1 mRNA
CTD
PMID:24136188
NCBI chr20:29,047,793...29,094,209
Ensembl chr20:29,047,796...29,094,084
G
Shc1
SHC adaptor protein 1
increases expression
EXP
valdecoxib results in increased expression of SHC1 mRNA
CTD
PMID:24136188
NCBI chr 2:174,837,937...174,849,538
Ensembl chr 2:174,837,930...174,849,536
G
Sik2
salt-inducible kinase 2
increases expression
EXP
valdecoxib results in increased expression of SIK2 mRNA
CTD
PMID:24136188
NCBI chr 8:51,225,543...51,325,343
Ensembl chr 8:51,225,543...51,325,415
G
Sirt3
sirtuin 3
decreases expression
EXP
valdecoxib results in decreased expression of SIRT3 mRNA
CTD
PMID:24136188
NCBI chr 1:195,942,066...195,964,472
Ensembl chr 1:195,942,073...195,964,808
G
Sirt5
sirtuin 5
decreases expression
EXP
valdecoxib results in decreased expression of SIRT5 mRNA
CTD
PMID:24136188
NCBI chr17:21,310,028...21,337,137
Ensembl chr17:21,310,028...21,337,101
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Slc16a7
solute carrier family 16 member 7
increases expression
EXP
valdecoxib results in increased expression of SLC16A7 mRNA
CTD
PMID:24136188
NCBI chr 7:61,043,667...61,211,547
Ensembl chr 7:61,051,167...61,154,994
G
Slc17a3
solute carrier family 17 member 3
increases expression
EXP
valdecoxib results in increased expression of SLC17A3 mRNA
CTD
PMID:24136188
NCBI chr17:41,270,804...41,300,132
Ensembl chr17:41,270,812...41,295,256
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Slc22a2
solute carrier family 22 member 2
multiple interactions
ISO
valdecoxib inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium]
CTD
PMID:21599003
NCBI chr 1:48,121,061...48,163,268
Ensembl chr 1:48,121,061...48,163,268
G
Slc22a5
solute carrier family 22 member 5
increases expression
EXP
valdecoxib results in increased expression of SLC22A5 mRNA
CTD
PMID:24136188
NCBI chr10:38,008,303...38,035,474
Ensembl chr10:38,008,311...38,035,309
G
Slc22a8
solute carrier family 22 member 8
decreases expression
EXP
valdecoxib results in decreased expression of SLC22A8 mRNA
CTD
PMID:24136188
NCBI chr 1:205,496,331...205,516,378
Ensembl chr 1:205,498,084...205,517,450
G
Slc25a12
solute carrier family 25 member 12
increases expression
EXP
valdecoxib results in increased expression of SLC25A12 mRNA
CTD
PMID:24136188
NCBI chr 3:56,097,166...56,191,841
Ensembl chr 3:56,097,269...56,192,100
G
Slc25a15
solute carrier family 25 member 15
decreases expression
EXP
valdecoxib results in decreased expression of SLC25A15 mRNA
CTD
PMID:24136188
NCBI chr16:69,631,581...69,654,869
Ensembl chr16:69,634,414...69,653,010
G
Slc25a23
solute carrier family 25 member 23
decreases expression
EXP
valdecoxib results in decreased expression of SLC25A23 mRNA
CTD
PMID:24136188
NCBI chr 9:1,882,636...1,898,369
Ensembl chr 9:1,882,621...1,898,561
G
Slc25a25
solute carrier family 25 member 25
decreases expression
EXP
valdecoxib results in decreased expression of SLC25A25 mRNA
CTD
PMID:24136188
NCBI chr 3:15,708,702...15,742,195
Ensembl chr 3:15,708,703...15,742,216
G
Slc25a37
solute carrier family 25 member 37
increases expression
EXP
valdecoxib results in increased expression of SLC25A37 mRNA
CTD
PMID:24136188
NCBI chr15:44,534,280...44,576,697
Ensembl chr15:44,536,727...44,577,199
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Slc2a2
solute carrier family 2 member 2
decreases expression
EXP
valdecoxib results in decreased expression of SLC2A2 mRNA
CTD
PMID:24136188
NCBI chr 2:111,609,798...111,639,930
Ensembl chr 2:111,611,774...111,639,933
G
Slc2a5
solute carrier family 2 member 5
decreases expression
EXP
valdecoxib results in decreased expression of SLC2A5 mRNA
CTD
PMID:24136188
NCBI chr 5:160,583,055...160,609,994
Ensembl chr 5:160,583,234...160,611,106
G
Slc31a1
solute carrier family 31 member 1
decreases expression
EXP
valdecoxib results in decreased expression of SLC31A1 mRNA
CTD
PMID:24136188
NCBI chr 5:75,814,744...75,844,241
Ensembl chr 5:75,814,743...75,844,228
G
Slc34a2
solute carrier family 34 member 2
decreases expression
EXP
valdecoxib results in decreased expression of SLC34A2 mRNA
CTD
PMID:24136188
NCBI chr14:57,910,931...57,930,236
Ensembl chr14:57,910,480...57,930,436
G
Slc35e3
solute carrier family 35, member E3
increases expression
EXP
valdecoxib results in increased expression of SLC35E3 mRNA
CTD
PMID:24136188
NCBI chr 7:53,337,091...53,350,152
Ensembl chr 7:53,337,095...53,350,165
G
Slc37a4
solute carrier family 37 member 4
decreases expression
EXP
valdecoxib results in decreased expression of SLC37A4 mRNA
CTD
PMID:24136188
NCBI chr 8:44,723,216...44,729,301
Ensembl chr 8:44,723,339...44,729,301
G
Slc39a10
solute carrier family 39 member 10
increases expression
EXP
valdecoxib results in increased expression of SLC39A10 mRNA
CTD
PMID:24136188
NCBI chr 9:54,836,841...54,960,325
Ensembl chr 9:54,876,141...54,960,325
G
Slc3a2
solute carrier family 3 member 2
increases expression
EXP
valdecoxib results in increased expression of SLC3A2 mRNA
CTD
PMID:24136188
NCBI chr 1:205,604,468...205,618,931
Ensembl chr 1:205,604,468...205,618,931
G
Slc43a1
solute carrier family 43 member 1
increases expression
EXP
valdecoxib results in increased expression of SLC43A1 mRNA
CTD
PMID:24136188
NCBI chr 3:69,920,586...69,946,768
Ensembl chr 3:69,920,649...69,946,768
G
Slc45a3
solute carrier family 45, member 3
decreases expression
EXP
valdecoxib results in decreased expression of SLC45A3 mRNA
CTD
PMID:24136188
NCBI chr13:43,407,293...43,427,588
Ensembl chr13:43,407,293...43,427,588
G
Slc46a1
solute carrier family 46 member 1
decreases expression
EXP
valdecoxib results in decreased expression of SLC46A1 mRNA
CTD
PMID:24136188
NCBI chr10:63,361,504...63,367,940
Ensembl chr10:63,361,486...63,368,848
G
Slc4a1
solute carrier family 4 member 1 (Diego blood group)
decreases expression
EXP
valdecoxib results in decreased expression of SLC4A1 mRNA
CTD
PMID:24136188
NCBI chr10:87,306,865...87,323,132
Ensembl chr10:87,306,872...87,323,117
G
Slc6a12
solute carrier family 6 member 12
decreases expression
EXP
valdecoxib results in decreased expression of SLC6A12 mRNA
CTD
PMID:24136188
NCBI chr 4:154,585,386...154,603,750
Ensembl chr 4:154,585,500...154,603,750
G
Slco1a4
solute carrier organic anion transporter family, member 1a4
increases expression
EXP
valdecoxib results in increased expression of SLCO1A2 mRNA
CTD
PMID:24136188
NCBI chr 4:174,710,004...174,764,810
Ensembl chr 4:174,710,004...175,254,573
G
Slco2a1
solute carrier organic anion transporter family, member 2a1
decreases expression
EXP
valdecoxib results in decreased expression of SLCO2A1 mRNA
CTD
PMID:24136188
NCBI chr 8:103,588,916...103,672,546
Ensembl chr 8:103,588,916...103,672,546
G
Slco2b1
solute carrier organic anion transporter family, member 2b1
decreases expression
EXP
valdecoxib results in decreased expression of SLCO2B1 mRNA
CTD
PMID:24136188
NCBI chr 1:153,959,288...154,007,294
Ensembl chr 1:153,959,293...154,007,353
G
Smim1
small integral membrane protein 1 (Vel blood group)
decreases expression
EXP
valdecoxib results in decreased expression of SMIM1 mRNA
CTD
PMID:24136188
NCBI chr 5:164,579,327...164,584,650
G
Smoc1
SPARC related modular calcium binding 1
decreases expression
EXP
valdecoxib results in decreased expression of SMOC1 mRNA
CTD
PMID:24136188
NCBI chr 6:100,701,330...100,897,441
Ensembl chr 6:100,701,346...100,862,699
G
Smyd4
SET and MYND domain containing 4
decreases expression
EXP
valdecoxib results in decreased expression of SMYD4 mRNA
CTD
PMID:24136188
NCBI chr10:60,200,067...60,246,387
Ensembl chr10:60,200,114...60,246,387
G
Snrnp48
small nuclear ribonucleoprotein U11/U12 subunit 48
increases expression
EXP
valdecoxib results in increased expression of SNRNP48 mRNA
CTD
PMID:24136188
NCBI chr17:26,596,266...26,616,058
Ensembl chr17:26,596,275...26,616,040
G
Snrpa
small nuclear ribonucleoprotein polypeptide A
increases expression
EXP
valdecoxib results in increased expression of SNRPA mRNA
CTD
PMID:24136188
NCBI chr 1:82,481,770...82,490,540
Ensembl chr 1:82,481,770...82,490,538
G
Snrpd3
small nuclear ribonucleoprotein D3 polypeptide
increases expression
EXP
valdecoxib results in increased expression of SNRPD3 mRNA
CTD
PMID:24136188
NCBI chr20:13,130,112...13,145,947
Ensembl chr20:13,130,119...13,145,978
G
Snrpg
small nuclear ribonucleoprotein polypeptide G
increases expression
EXP
valdecoxib results in increased expression of SNRPG mRNA
CTD
PMID:24136188
NCBI chr 4:118,812,278...118,819,827
Ensembl chr 4:118,812,252...118,819,826 Ensembl chr X:118,812,252...118,819,826
G
Snx11
sorting nexin 11
decreases expression
EXP
valdecoxib results in decreased expression of SNX11 mRNA
CTD
PMID:24136188
NCBI chr10:81,742,020...81,752,778
Ensembl chr10:81,742,024...81,752,712
G
Sod2
superoxide dismutase 2
increases expression
EXP
valdecoxib results in increased expression of SOD2 mRNA
CTD
PMID:24136188
NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
G
Spink1
serine peptidase inhibitor, Kazal type 1
decreases expression
EXP
valdecoxib results in decreased expression of SPINK1 mRNA
CTD
PMID:24136188
NCBI chr18:35,870,723...35,882,693
Ensembl chr18:35,824,550...35,882,642
G
Spryd7
SPRY domain containing 7
increases expression
EXP
valdecoxib results in increased expression of SPRYD7 mRNA
CTD
PMID:24136188
NCBI chr15:35,707,185...35,727,704
Ensembl chr15:35,707,060...35,727,509
G
Sptan1
spectrin, alpha, non-erythrocytic 1
increases expression
EXP
valdecoxib results in increased expression of SPTAN1 mRNA
CTD
PMID:24136188
NCBI chr 3:13,241,164...13,306,047
Ensembl chr 3:13,241,217...13,306,046
G
Sptbn2
spectrin, beta, non-erythrocytic 2
increases expression
EXP
valdecoxib results in increased expression of SPTBN2 mRNA
CTD
PMID:24136188
NCBI chr 1:202,002,970...202,045,343
Ensembl chr 1:202,002,970...202,044,283
G
Sqle
squalene epoxidase
increases expression
EXP
valdecoxib results in increased expression of SQLE mRNA
CTD
PMID:24136188
NCBI chr 7:90,867,973...90,883,623
Ensembl chr 7:90,868,011...90,883,618
G
Srd5a3
steroid 5 alpha-reductase 3
increases expression
EXP
valdecoxib results in increased expression of SRD5A3 mRNA
CTD
PMID:24136188
NCBI chr14:32,046,408...32,060,796
Ensembl chr14:32,046,408...32,060,747
G
Srebf1
sterol regulatory element binding transcription factor 1
decreases expression
EXP
valdecoxib results in decreased expression of SREBF1 mRNA
CTD
PMID:24136188
NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650
G
Srebf2
sterol regulatory element binding transcription factor 2
increases expression
EXP
valdecoxib results in increased expression of SREBF2 mRNA
CTD
PMID:24136188
NCBI chr 7:113,663,202...113,720,850
Ensembl chr 7:113,663,202...113,720,848
G
Sri
sorcin
increases expression
EXP
valdecoxib results in increased expression of SRI mRNA
CTD
PMID:24136188
NCBI chr 4:25,973,493...25,997,879
Ensembl chr 4:25,966,750...25,998,077
G
Srm
spermidine synthase
increases expression
EXP
valdecoxib results in increased expression of SRM mRNA
CTD
PMID:24136188
NCBI chr 5:159,025,875...159,029,076
Ensembl chr 5:159,025,873...159,029,405
G
St6gal1
ST6 beta-galactoside alpha-2,6-sialyltransferase 1
decreases expression
EXP
valdecoxib results in decreased expression of ST6GAL1 mRNA
CTD
PMID:24136188
NCBI chr11:77,526,837...77,653,474
Ensembl chr11:77,526,837...77,653,310
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St8sia3
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
decreases expression
EXP
valdecoxib results in decreased expression of ST8SIA3 mRNA
CTD
PMID:24136188
NCBI chr18:57,754,349...57,760,839
Ensembl chr18:57,754,347...57,760,839
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Stac3
SH3 and cysteine rich domain 3
decreases expression
EXP
valdecoxib results in decreased expression of STAC3 mRNA
CTD
PMID:24136188
NCBI chr 7:63,343,078...63,350,590
Ensembl chr 7:63,343,186...63,350,589
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Stag1
STAG1 cohesin complex component
decreases expression
EXP
valdecoxib results in decreased expression of STAG1 mRNA
CTD
PMID:24136188
NCBI chr 8:101,179,039...101,564,684
Ensembl chr 8:101,179,039...101,564,677
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Stard3nl
STARD3 N-terminal like
increases expression
EXP
valdecoxib results in increased expression of STARD3NL mRNA
CTD
PMID:24136188
NCBI chr17:45,583,278...45,617,226
Ensembl chr17:45,583,266...45,617,226
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Stard5
StAR-related lipid transfer domain containing 5
decreases expression
EXP
valdecoxib results in decreased expression of STARD5 mRNA
CTD
PMID:24136188
NCBI chr 1:137,606,151...137,616,017
Ensembl chr 1:137,606,177...137,616,469
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Stat3
signal transducer and activator of transcription 3
increases expression
EXP
valdecoxib results in increased expression of STAT3 mRNA
CTD
PMID:24136188
NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057
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Stbd1
starch binding domain 1
increases expression
EXP
valdecoxib results in increased expression of STBD1 mRNA
CTD
PMID:24136188
NCBI chr14:15,470,452...15,473,857
Ensembl chr14:15,469,582...15,477,443
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Steap3
STEAP3 metalloreductase
decreases expression
EXP
valdecoxib results in decreased expression of STEAP3 mRNA
CTD
PMID:24136188
NCBI chr13:31,351,954...31,397,344
Ensembl chr13:31,351,954...31,396,519
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Stip1
stress-induced phosphoprotein 1
increases expression
EXP
valdecoxib results in increased expression of STIP1 mRNA
CTD
PMID:24136188
NCBI chr 1:204,209,433...204,228,452
Ensembl chr 1:204,178,932...204,228,476
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Sult1a1
sulfotransferase family 1A member 1
decreases expression
EXP
valdecoxib results in decreased expression of SULT1A1 mRNA
CTD
PMID:24136188
NCBI chr 1:181,272,022...181,276,750
Ensembl chr 1:181,272,023...181,275,562
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Suox
sulfite oxidase
decreases expression
EXP
valdecoxib results in decreased expression of SUOX mRNA
CTD
PMID:24136188
NCBI chr 7:1,103,149...1,107,156
Ensembl chr 7:1,103,151...1,107,038
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Sytl2
synaptotagmin-like 2
decreases expression
EXP
valdecoxib results in decreased expression of SYTL2 mRNA
CTD
PMID:24136188
NCBI chr 1:144,272,870...144,379,310
Ensembl chr 1:144,273,360...144,379,222
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Tat
tyrosine aminotransferase
decreases expression
EXP
valdecoxib results in decreased expression of TAT mRNA
CTD
PMID:24136188
NCBI chr19:37,947,153...37,957,717
Ensembl chr19:37,947,112...37,958,031
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Tbc1d15
TBC1 domain family, member 15
increases expression
EXP
valdecoxib results in increased expression of TBC1D15 mRNA
CTD
PMID:24136188
NCBI chr 7:50,804,553...50,860,272
Ensembl chr 7:50,804,012...50,860,175
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Tbl3
transducin (beta)-like 3
increases expression
EXP
valdecoxib results in increased expression of TBL3 mRNA
CTD
PMID:24136188
NCBI chr10:13,726,127...13,731,340
Ensembl chr10:13,726,129...13,731,372
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Tcp1
t-complex 1
increases expression
EXP
valdecoxib results in increased expression of TCP1 mRNA
CTD
PMID:24136188
NCBI chr 1:47,829,061...47,836,809
Ensembl chr 1:47,828,652...47,836,839
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Tex2
testis expressed 2
increases expression
EXP
valdecoxib results in increased expression of TEX2 mRNA
CTD
PMID:24136188
NCBI chr10:91,436,629...91,546,240
Ensembl chr10:91,436,694...91,546,270
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Tfam
transcription factor A, mitochondrial
increases expression
EXP
valdecoxib results in increased expression of TFAM mRNA
CTD
PMID:24136188
NCBI chr20:17,356,243...17,368,293
Ensembl chr20:17,356,197...17,368,292
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Thnsl2
threonine synthase-like 2
decreases expression
EXP
valdecoxib results in decreased expression of THNSL2 mRNA
CTD
PMID:24136188
NCBI chr 4:103,112,974...103,132,122
Ensembl chr 4:103,112,963...103,132,017
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Thrsp
thyroid hormone responsive
decreases expression
EXP
valdecoxib results in decreased expression of THRSP mRNA
CTD
PMID:24136188
NCBI chr 1:151,723,415...151,727,740
Ensembl chr 1:151,723,086...151,728,075
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Timm10b
translocase of inner mitochondrial membrane 10B
increases expression
EXP
valdecoxib results in increased expression of TIMM10B mRNA
CTD
PMID:24136188
NCBI chr 1:159,980,525...159,983,371
Ensembl chr 1:159,980,484...159,981,642 Ensembl chr20:159,980,484...159,981,642
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Timm29
translocase of inner mitochondrial membrane 29
increases expression
EXP
valdecoxib results in increased expression of TIMM29 mRNA
CTD
PMID:24136188
NCBI chr 8:20,145,264...20,148,233
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Tkfc
triokinase and FMN cyclase
decreases expression
EXP
valdecoxib results in decreased expression of TKFC mRNA
CTD
PMID:24136188
NCBI chr 1:207,238,230...207,253,035
Ensembl chr 1:207,236,557...207,252,737
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Tkt
transketolase
increases expression
EXP
valdecoxib results in increased expression of TKT mRNA
CTD
PMID:24136188
NCBI chr16:5,723,764...5,748,702
Ensembl chr16:5,723,762...5,748,698
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Tlcd4
TLC domain containing 4
increases expression
EXP
valdecoxib results in increased expression of TLCD4 mRNA
CTD
PMID:24136188
NCBI chr 2:209,284,873...209,360,156
Ensembl chr 2:209,289,732...209,341,353
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Tle3
TLE family member 3, transcriptional corepressor
decreases expression
EXP
valdecoxib results in decreased expression of TLE3 mRNA
CTD
PMID:24136188
NCBI chr 8:61,857,791...61,903,505
Ensembl chr 8:61,858,200...61,903,493
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Tm2d3
TM2 domain containing 3
increases expression
EXP
valdecoxib results in increased expression of TM2D3 mRNA
CTD
PMID:24136188
NCBI chr 1:119,267,194...119,277,094
Ensembl chr 1:119,264,576...119,277,099
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Tmcc1
transmembrane and coiled-coil domain family 1
decreases expression
EXP
valdecoxib results in decreased expression of TMCC1 mRNA
CTD
PMID:24136188
NCBI chr 4:149,069,252...149,239,585
Ensembl chr 4:149,069,260...149,239,620
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Tmem132a
transmembrane protein 132A
increases expression
EXP
valdecoxib results in increased expression of TMEM132A mRNA
CTD
PMID:24136188
NCBI chr 1:207,507,074...207,518,756
Ensembl chr 1:207,507,077...207,518,758
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Tmem135
transmembrane protein 135
increases expression
EXP
valdecoxib results in increased expression of TMEM135 mRNA
CTD
PMID:24136188
NCBI chr 1:143,006,343...143,279,824
Ensembl chr 1:143,006,344...143,221,171
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Tmem218
transmembrane protein 218
decreases expression
EXP
valdecoxib results in decreased expression of TMEM218 mRNA
CTD
PMID:24136188
NCBI chr 8:36,924,553...36,940,564
Ensembl chr 8:36,924,585...36,939,927
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Tmem259
transmembrane protein 259
increases expression
EXP
valdecoxib results in increased expression of TMEM259 mRNA
CTD
PMID:24136188
NCBI chr 7:9,724,196...9,730,932
Ensembl chr 7:9,722,485...9,730,932
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Tmem30b
transmembrane protein 30B
increases expression
EXP
valdecoxib results in increased expression of TMEM30B mRNA
CTD
PMID:24136188
NCBI chr 6:92,251,626...92,254,702
Ensembl chr 6:92,249,790...92,254,842
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Tnf
tumor necrosis factor
increases expression
EXP
valdecoxib results in increased expression of TNF
CTD
PMID:24136188
NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
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Tnfrsf1a
TNF receptor superfamily member 1A
increases expression
EXP
valdecoxib results in increased expression of TNFRSF1A mRNA
CTD
PMID:24136188
NCBI chr 4:158,150,815...158,163,592
Ensembl chr 4:158,150,820...158,163,591
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Tnpo1
transportin 1
increases expression
EXP
valdecoxib results in increased expression of TNPO1 mRNA
CTD
PMID:24136188
NCBI chr 2:30,207,529...30,300,162
Ensembl chr 2:30,211,510...30,300,375
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Tom1
target of myb1 membrane trafficking protein
decreases expression
EXP
valdecoxib results in decreased expression of TOM1 mRNA
CTD
PMID:24136188
NCBI chr19:13,405,482...13,440,384
Ensembl chr19:13,405,501...13,440,384
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Tpm1
tropomyosin 1
increases expression
EXP
valdecoxib results in increased expression of TPM1 mRNA
CTD
PMID:24136188
NCBI chr 8:67,635,479...67,662,330
Ensembl chr 8:67,635,479...67,662,802
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Trib3
tribbles pseudokinase 3
increases expression
EXP
valdecoxib results in increased expression of TRIB3 mRNA
CTD
PMID:24136188
NCBI chr 3:140,809,634...140,815,230
Ensembl chr 3:140,809,043...140,814,497
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Trim37
tripartite motif-containing 37
increases expression
EXP
valdecoxib results in increased expression of TRIM37 mRNA
CTD
PMID:24136188
NCBI chr10:71,943,384...72,075,563
Ensembl chr10:71,943,375...72,075,558
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Trim5
tripartite motif-containing 5
decreases expression
EXP
valdecoxib results in decreased expression of TRIM5 mRNA
CTD
PMID:24136188
NCBI chr 1:158,720,407...158,737,393
Ensembl chr 1:158,720,410...158,814,012
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Tsc22d1
TSC22 domain family, member 1
decreases expression
EXP
valdecoxib results in decreased expression of TSC22D1 mRNA
CTD
PMID:24136188
NCBI chr15:51,750,489...51,850,958
Ensembl chr15:51,749,510...51,850,958
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Tsc22d3
TSC22 domain family, member 3
decreases expression
EXP
valdecoxib results in decreased expression of TSC22D3 mRNA
CTD
PMID:24136188
NCBI chr X:104,217,898...104,277,886
Ensembl chr X:104,217,925...104,276,861
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Tspyl4
TSPY-like 4
decreases expression
EXP
valdecoxib results in decreased expression of TSPYL4 mRNA
CTD
PMID:24136188
NCBI chr20:38,098,756...38,100,752
Ensembl chr20:38,098,677...38,103,053
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Ttc27
tetratricopeptide repeat domain 27
increases expression
EXP
valdecoxib results in increased expression of TTC27 mRNA
CTD
PMID:24136188
NCBI chr 6:20,558,756...20,702,126
Ensembl chr 6:20,558,756...20,702,115
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Tuba1c
tubulin, alpha 1C
increases expression
EXP
valdecoxib results in increased expression of TUBA1C mRNA
CTD
PMID:24136188
NCBI chr 7:130,192,050...130,199,655
Ensembl chr 7:130,192,016...130,199,647 Ensembl chr X:130,192,016...130,199,647
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Tuba4a
tubulin, alpha 4A
increases expression
EXP
valdecoxib results in increased expression of TUBA4A mRNA
CTD
PMID:24136188
NCBI chr 9:76,709,617...76,714,327
Ensembl chr 9:76,709,614...76,713,918
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Tubb4b
tubulin, beta 4B class IVb
increases expression
EXP
valdecoxib results in increased expression of TUBB4B mRNA
CTD
PMID:24136188
NCBI chr 3:8,037,838...8,040,294
Ensembl chr 3:8,037,799...8,040,296
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Txn1
thioredoxin 1
increases expression
EXP
valdecoxib results in increased expression of TXN1 mRNA
CTD
PMID:24136188
NCBI chr 5:72,712,334...72,724,564
Ensembl chr 5:72,711,933...72,724,629
G
Txnl1
thioredoxin-like 1
increases expression
EXP
valdecoxib results in increased expression of TXNL1 mRNA
CTD
PMID:24136188
NCBI chr18:57,125,362...57,155,167
Ensembl chr18:57,125,369...57,165,266
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Txnrd1
thioredoxin reductase 1
increases expression
EXP
valdecoxib results in increased expression of TXNRD1 mRNA
CTD
PMID:24136188
NCBI chr 7:20,830,042...20,914,990
Ensembl chr 7:20,830,045...20,907,863
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Uap1
UDP-N-acetylglucosamine pyrophosphorylase 1
decreases expression
EXP
valdecoxib results in decreased expression of UAP1 mRNA
CTD
PMID:24136188
NCBI chr13:82,342,946...82,377,558
Ensembl chr13:82,342,946...82,377,469 Ensembl chr 6:82,342,946...82,377,469
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Ube2c
ubiquitin-conjugating enzyme E2C
decreases expression
EXP
valdecoxib results in decreased expression of UBE2C mRNA
CTD
PMID:24136188
NCBI chr 3:153,506,636...153,509,036
Ensembl chr 3:153,506,636...153,513,339
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Ube4b
ubiquitination factor E4B
increases expression
EXP
valdecoxib results in increased expression of UBE4B mRNA
CTD
PMID:24136188
NCBI chr 5:159,766,829...159,870,509
Ensembl chr 5:159,766,829...159,870,509
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Ubqln1
ubiquilin 1
increases expression
EXP
valdecoxib results in increased expression of UBQLN1 mRNA
CTD
PMID:24136188
NCBI chr17:6,439,002...6,477,096
Ensembl chr17:6,439,002...6,477,090
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Ubqln2
ubiquilin 2
increases expression
EXP
valdecoxib results in increased expression of UBQLN2 mRNA
CTD
PMID:24136188
NCBI chr X:17,853,086...17,856,505
Ensembl chr X:17,853,114...17,856,505
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Ubr3
ubiquitin protein ligase E3 component n-recognin 3
increases expression
EXP
valdecoxib results in increased expression of UBR3 mRNA
CTD
PMID:24136188
NCBI chr 3:54,649,803...54,806,779
Ensembl chr 3:54,649,992...54,806,247
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Ubxn2a
UBX domain protein 2A
increases expression
EXP
valdecoxib results in increased expression of UBXN2A mRNA
CTD
PMID:24136188
NCBI chr 6:27,884,364...27,912,767
Ensembl chr 6:27,884,680...27,912,649 Ensembl chr20:27,884,680...27,912,649
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Ubxn4
UBX domain protein 4
increases expression
EXP
valdecoxib results in increased expression of UBXN4 mRNA
CTD
PMID:24136188
NCBI chr13:39,740,064...39,772,493
Ensembl chr13:39,740,107...39,772,491
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Ufd1
ubiquitin recognition factor in ER associated degradation 1
increases expression
EXP
valdecoxib results in increased expression of UFD1 mRNA
CTD
PMID:24136188
NCBI chr11:82,161,618...82,185,107
Ensembl chr11:82,161,619...82,185,087
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Ugdh
UDP-glucose 6-dehydrogenase
increases expression
EXP
valdecoxib results in increased expression of UGDH mRNA
CTD
PMID:24136188
NCBI chr14:42,848,704...42,872,351
Ensembl chr14:42,848,854...42,872,354
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Ugt1a6
UDP glucuronosyltransferase family 1 member A6
increases expression
EXP
valdecoxib results in increased expression of UGT1A6 mRNA
CTD
PMID:24136188
NCBI chr 9:88,747,213...88,808,465
Ensembl chr 9:88,713,184...88,808,465
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Ugt2a1
UDP glucuronosyltransferase family 2 member A1
increases expression
EXP
valdecoxib results in increased expression of UGT2A1 mRNA
CTD
PMID:24136188
NCBI chr14:20,521,018...20,545,934
Ensembl chr14:20,517,951...20,545,531
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Ugt2b1
UDP glucuronosyltransferase 2 family, polypeptide B1
increases expression
EXP
valdecoxib results in increased expression of UGT2B17 mRNA
CTD
PMID:24136188
NCBI chr14:21,024,035...21,035,784
Ensembl chr14:21,024,006...21,035,986
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Unc5cl
unc-5 family C-terminal like
increases expression
EXP
valdecoxib results in increased expression of UNC5CL mRNA
CTD
PMID:24136188
NCBI chr 9:12,528,109...12,543,382
Ensembl chr 9:12,528,246...12,542,233
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Unkl
unk like zinc finger
increases expression
EXP
valdecoxib results in increased expression of UNKL mRNA
CTD
PMID:24136188
NCBI chr10:14,206,125...14,252,226
Ensembl chr10:14,206,189...14,252,225
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Uri1
URI1, prefoldin-like chaperone
increases expression
EXP
valdecoxib results in increased expression of URI1 mRNA
CTD
PMID:24136188
NCBI chr 1:90,646,392...90,704,811
Ensembl chr 1:90,646,393...90,709,026
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Usp14
ubiquitin specific peptidase 14
increases expression
EXP
valdecoxib results in increased expression of USP14 mRNA
CTD
PMID:24136188
NCBI chr18:1,018,111...1,057,727
Ensembl chr18:1,019,400...1,057,519
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Usp2
ubiquitin specific peptidase 2
decreases expression
EXP
valdecoxib results in decreased expression of USP2 mRNA
CTD
PMID:24136188
NCBI chr 8:44,411,457...44,439,668
Ensembl chr 8:44,411,607...44,438,331
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Usp33
ubiquitin specific peptidase 33
increases expression
EXP
valdecoxib results in increased expression of USP33 mRNA
CTD
PMID:24136188
NCBI chr 2:241,283,209...241,328,479
Ensembl chr 2:241,292,985...241,328,479
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Usp5
ubiquitin specific peptidase 5
increases expression
EXP
valdecoxib results in increased expression of USP5 mRNA
CTD
PMID:24136188
NCBI chr 4:157,619,663...157,634,681
Ensembl chr 4:157,619,643...157,634,711
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Vav2
vav guanine nucleotide exchange factor 2
increases expression
EXP
valdecoxib results in increased expression of VAV2 mRNA
CTD
PMID:24136188
NCBI chr 3:10,584,688...10,754,128
Ensembl chr 3:10,584,688...10,754,052
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Vcp
valosin-containing protein
increases expression
EXP
valdecoxib results in increased expression of VCP mRNA
CTD
PMID:24136188
NCBI chr 5:57,210,167...57,229,571
Ensembl chr 5:57,210,168...57,229,571
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Vegfa
vascular endothelial growth factor A
increases secretion
ISO
valdecoxib results in increased secretion of VEGFA protein
CTD
PMID:24431307
NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
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Vegfb
vascular endothelial growth factor B
increases expression
EXP
valdecoxib results in increased expression of VEGFB mRNA
CTD
PMID:24136188
NCBI chr 1:204,172,297...204,178,046
Ensembl chr 1:204,172,225...204,177,944
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Veph1
ventricular zone expressed PH domain-containing 1
decreases expression
EXP
valdecoxib results in decreased expression of VEPH1 mRNA
CTD
PMID:24136188
NCBI chr 2:150,291,379...150,537,491
Ensembl chr 2:150,296,573...150,537,266
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Vnn1
vanin 1
increases expression
EXP
valdecoxib results in increased expression of VNN1 mRNA
CTD
PMID:24136188
NCBI chr 1:21,537,084...21,547,395
Ensembl chr 1:21,537,094...21,547,395
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Vps26a
VPS26 retromer complex component A
increases expression
EXP
valdecoxib results in increased expression of VPS26A mRNA
CTD
PMID:24136188
NCBI chr20:30,404,320...30,434,266
Ensembl chr20:30,404,325...30,434,131
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Vwa8
von Willebrand factor A domain containing 8
increases expression
EXP
valdecoxib results in increased expression of VWA8 mRNA
CTD
PMID:24136188
NCBI chr15:54,252,703...54,576,871
Ensembl chr15:54,252,584...54,576,870
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Wdr33
WD repeat domain 33
decreases expression
EXP
valdecoxib results in decreased expression of WDR33 mRNA
CTD
PMID:24136188
NCBI chr18:23,432,233...23,535,460
Ensembl chr18:23,432,191...23,468,597
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Wdr6
WD repeat domain 6
decreases expression
EXP
valdecoxib results in decreased expression of WDR6 mRNA
CTD
PMID:24136188
NCBI chr 8:109,268,079...109,274,504
Ensembl chr 8:109,268,079...109,274,499
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Wwc1
WW and C2 domain containing 1
increases expression
EXP
valdecoxib results in increased expression of WWC1 mRNA
CTD
PMID:24136188
NCBI chr10:20,300,735...20,454,393
Ensembl chr10:20,300,833...20,454,497
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Xiap
X-linked inhibitor of apoptosis
decreases expression
EXP
valdecoxib results in decreased expression of XIAP mRNA
CTD
PMID:24136188
NCBI chr X:120,890,537...120,938,413
Ensembl chr X:120,897,907...120,934,700
G
Xpc
XPC complex subunit, DNA damage recognition and repair factor
decreases expression
EXP
valdecoxib results in decreased expression of XPC mRNA
CTD
PMID:24136188
NCBI chr 4:123,993,670...124,020,922
Ensembl chr 4:123,993,666...124,021,010
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Xpnpep2
X-prolyl aminopeptidase 2
decreases expression
EXP
valdecoxib results in decreased expression of XPNPEP2 mRNA
CTD
PMID:24136188
NCBI chr X:127,287,765...127,317,036
Ensembl chr X:127,287,979...127,317,223
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Xpot
exportin for tRNA
increases expression
EXP
valdecoxib results in increased expression of XPOT mRNA
CTD
PMID:24136188
NCBI chr 7:57,111,536...57,152,013
Ensembl chr 7:57,111,536...57,152,099
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Yars2
tyrosyl-tRNA synthetase 2
increases expression
EXP
valdecoxib results in increased expression of YARS2 mRNA
CTD
PMID:24136188
NCBI chr11:84,632,350...84,638,138
Ensembl chr11:84,624,369...84,638,125
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Zan
zonadhesin
increases expression
EXP
valdecoxib results in increased expression of ZAN mRNA
CTD
PMID:24136188
NCBI chr12:19,215,018...19,322,789
Ensembl chr12:19,215,102...19,271,240
G
Zdhhc2
zinc finger DHHC-type palmitoyltransferase 2
increases expression
EXP
valdecoxib results in increased expression of ZDHHC2 mRNA
CTD
PMID:24136188
NCBI chr16:51,808,465...51,878,060
Ensembl chr16:51,808,468...51,878,060
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Zfand2a
zinc finger AN1-type containing 2A
increases expression
EXP
valdecoxib results in increased expression of ZFAND2A mRNA
CTD
PMID:24136188
NCBI chr12:15,161,601...15,172,679
Ensembl chr12:15,161,639...15,172,677
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Zfand5
zinc finger AN1-type containing 5
increases expression
EXP
valdecoxib results in increased expression of ZFAND5 mRNA
CTD
PMID:24136188
NCBI chr 1:218,765,735...218,780,391
Ensembl chr 1:218,766,614...218,775,843
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Zfp189
zinc finger protein 189
decreases expression
EXP
valdecoxib results in decreased expression of ZFP189 mRNA
CTD
PMID:24136188
NCBI chr 5:63,872,596...63,884,348
Ensembl chr 5:63,872,738...63,884,121
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Zfp266
zinc finger protein 266
decreases expression
EXP
valdecoxib results in decreased expression of ZFP266 mRNA
CTD
PMID:24136188
NCBI chr 8:19,030,766...19,061,381
Ensembl chr 8:19,030,768...19,060,937
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Zfp292
zinc finger protein 292
increases expression
EXP
valdecoxib results in increased expression of ZFP292 mRNA
CTD
PMID:24136188
NCBI chr 5:49,384,177...49,468,177
Ensembl chr 5:49,387,893...49,468,265
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Zfp354a
zinc finger protein 354A
decreases expression
EXP
valdecoxib results in decreased expression of ZFP354A mRNA
CTD
PMID:24136188
NCBI chr10:35,396,242...35,408,069
Ensembl chr10:35,396,231...35,408,068
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Zfp36l2
zinc finger protein 36, C3H type-like 2
increases expression
EXP
valdecoxib results in increased expression of ZFP36L2 mRNA
CTD
PMID:24136188
NCBI chr 6:10,490,032...10,494,073
Ensembl chr 6:10,490,032...10,494,064
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Zfp593
zinc finger protein 593
increases expression
EXP
valdecoxib results in increased expression of ZFP593 mRNA
CTD
PMID:24136188
NCBI chr 5:146,462,670...146,464,998
Ensembl chr 5:146,462,670...146,465,198
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Zrsr2-ps1
zinc finger (CCCH type), RNA binding motif and serine/arginine rich 2, pseudogene 1
increases expression
EXP
valdecoxib results in increased expression of ZRSR2-PS1 mRNA
CTD
PMID:24136188
NCBI chr14:96,972,651...96,978,364
Ensembl chr14:96,972,580...96,978,891
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Zwint
ZW10 interacting kinetochore protein
increases expression
EXP
valdecoxib results in increased expression of ZWINT mRNA
CTD
PMID:24136188
NCBI chr20:15,938,157...15,953,997
Ensembl chr20:15,938,157...15,953,957
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Cdh1
cadherin 1
increases expression
ISO
parecoxib results in increased expression of CDH1 protein
CTD
PMID:35917206
NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775
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Cnr1
cannabinoid receptor 1
increases response to substance
ISO
CNR1 protein results in increased susceptibility to parecoxib
CTD
PMID:23371449
NCBI chr 5:48,408,543...48,436,099
Ensembl chr 5:48,408,574...48,435,099
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Ctnnb1
catenin beta 1
decreases expression
ISO
parecoxib results in decreased expression of CTNNB1 protein
CTD
PMID:35917206
NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111
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Gsk3b
glycogen synthase kinase 3 beta
decreases expression increases expression
ISO
parecoxib results in decreased expression of GSK3B protein modified form parecoxib results in increased expression of GSK3B protein
CTD
PMID:35917206
NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
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Macc1
MET transcriptional regulator MACC1
decreases expression
ISO
parecoxib results in decreased expression of MACC1 protein
CTD
PMID:35917206
NCBI chr 6:140,352,690...140,430,255
Ensembl chr 6:140,352,755...140,430,255
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Mapk1
mitogen activated protein kinase 1
decreases phosphorylation
ISO
parecoxib results in decreased phosphorylation of MAPK1 protein
CTD
PMID:35917206
NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
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Mapk3
mitogen activated protein kinase 3
decreases phosphorylation
ISO
parecoxib results in decreased phosphorylation of MAPK3 protein
CTD
PMID:35917206
NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
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Mapk8
mitogen-activated protein kinase 8
increases phosphorylation
ISO
parecoxib results in increased phosphorylation of MAPK8 protein
CTD
PMID:35917206
NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981
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Mapk9
mitogen-activated protein kinase 9
increases phosphorylation
ISO
parecoxib results in increased phosphorylation of MAPK9 protein
CTD
PMID:35917206
NCBI chr10:34,169,661...34,211,138
Ensembl chr10:34,169,675...34,210,178
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Met
MET proto-oncogene, receptor tyrosine kinase
decreases expression
ISO
parecoxib results in decreased expression of MET protein
CTD
PMID:35917206
NCBI chr 4:45,790,456...45,898,139
Ensembl chr 4:45,790,791...45,897,876
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Vim
vimentin
decreases expression
ISO
parecoxib results in decreased expression of VIM protein
CTD
PMID:35917206
NCBI chr17:76,668,701...76,677,186
Ensembl chr17:76,668,647...76,677,187
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