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G |
Ace2 |
angiotensin converting enzyme 2 |
decreases expression |
ISO |
Acarbose results in decreased expression of ACE2 mRNA |
CTD |
PMID:32808185 |
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NCBI chr X:30,293,597...30,340,961
Ensembl chr X:30,293,589...30,340,977
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G |
Adipoq |
adiponectin, C1Q and collagen domain containing |
increases expression |
EXP |
Acarbose results in increased expression of ADIPOQ protein |
CTD |
PMID:18290871 |
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NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564
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G |
Ccl2 |
C-C motif chemokine ligand 2 |
multiple interactions |
EXP |
Acarbose inhibits the reaction [Fructose results in increased expression of CCL2 mRNA]; Acarbose inhibits the reaction [Fructose results in increased expression of CCL2 protein] |
CTD |
PMID:17133782 |
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NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
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G |
Cyp2e1 |
cytochrome P450, family 2, subfamily e, polypeptide 1 |
decreases expression |
EXP |
Acarbose results in decreased expression of CYP2E1 mRNA |
CTD |
PMID:14975757 |
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NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
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G |
Fasn |
fatty acid synthase |
decreases expression |
EXP |
Acarbose results in decreased expression of FASN mRNA; Acarbose results in decreased expression of FASN protein |
CTD |
PMID:8101498 |
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NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261
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G |
Ins1 |
insulin 1 |
increases response to substance multiple interactions increases secretion decreases expression decreases secretion |
EXP |
Acarbose results in increased susceptibility to INS1 protein Acarbose inhibits the reaction [[Dietary Sucrose co-treated with Sodium Chloride, Dietary] results in increased expression of INS1 protein] Acarbose results in increased secretion of INS1 protein Acarbose results in decreased expression of INS1 protein Acarbose results in decreased secretion of INS1 protein |
CTD |
PMID:1767839 PMID:8101498 PMID:9313782 PMID:18290871 |
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NCBI chr 1:251,244,973...251,245,540
Ensembl chr 1:251,244,973...251,245,536
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G |
Lep |
leptin |
decreases expression |
EXP |
Acarbose results in decreased expression of LEP protein |
CTD |
PMID:18290871 |
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NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262
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G |
Mgam |
maltase-glucoamylase |
decreases activity |
ISO |
Acarbose results in decreased activity of MGAM protein |
CTD |
PMID:17585022 PMID:20349118 |
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NCBI chr 4:69,441,626...69,602,068
Ensembl chr 4:69,446,150...69,692,715
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G |
Npy |
neuropeptide Y |
decreases expression |
EXP |
Acarbose results in decreased expression of NPY protein |
CTD |
PMID:18290871 |
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NCBI chr 4:78,881,294...78,888,495
Ensembl chr 4:78,881,264...78,888,495
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G |
Ppargc1a |
PPARG coactivator 1 alpha |
affects response to substance |
ISO |
PPARGC1A protein polymorphism affects the susceptibility to Acarbose |
CTD |
PMID:15592662 |
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NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656
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G |
Slc2a1 |
solute carrier family 2 member 1 |
increases expression |
EXP |
Acarbose results in increased expression of SLC2A1 protein |
CTD |
PMID:11779583 |
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NCBI chr 5:132,717,196...132,745,416
Ensembl chr 5:132,717,196...132,745,416
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G |
Slc2a4 |
solute carrier family 2 member 4 |
increases expression |
EXP |
Acarbose results in increased expression of SLC2A4 mRNA; Acarbose results in increased expression of SLC2A4 protein |
CTD |
PMID:1767839 |
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NCBI chr10:54,666,015...54,671,581
Ensembl chr10:54,666,015...54,671,565
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G |
Sqstm1 |
sequestosome 1 |
affects response to substance |
ISO |
SQSTM1 affects the susceptibility to Acarbose |
CTD |
PMID:19207582 |
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NCBI chr10:34,525,517...34,536,670
Ensembl chr10:34,525,519...34,536,673
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G |
Tnf |
tumor necrosis factor |
decreases expression multiple interactions |
ISO EXP |
Acarbose results in decreased expression of TNF mRNA Acarbose results in decreased expression of TNF mRNA; Acarbose results in decreased expression of TNF protein Acarbose inhibits the reaction [Oxygen deficiency results in increased expression of TNF mRNA] |
CTD |
PMID:12717270 PMID:14975757 PMID:20703014 |
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NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
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G |
Nos2 |
nitric oxide synthase 2 |
multiple interactions |
ISO |
ganglioside, GD1b analog inhibits the reaction [[lipopolysaccharide, E. coli O26-B6 results in increased activity of NOS2 protein] which results in increased secretion of Nitrites]; ganglioside, GD1b inhibits the reaction [[lipopolysaccharide, E. coli O26-B6 results in increased activity of NOS2 protein] which results in increased secretion of Nitrites] |
CTD |
PMID:31202640 |
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NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
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