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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:oligosaccharide derivative
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Accession:CHEBI:63563 term browser browse the term
Definition:A carbohydrate derivative that is formally obtained from an oligosaccharide.
Synonyms:related_synonym: O-glycosylglycoside derivative;   O-glycosylglycoside derivatives;   oligosaccharide derivatives



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acarbose term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ace2 angiotensin converting enzyme 2 decreases expression ISO Acarbose results in decreased expression of ACE2 mRNA CTD PMID:32808185 NCBI chr  X:162,922,338...162,971,414
Ensembl chr  X:162,922,328...162,971,416
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing increases expression ISO Acarbose results in increased expression of ADIPOQ protein CTD PMID:18290871 NCBI chr16:22,965,286...22,976,718
Ensembl chr16:22,965,286...22,976,778
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions ISO Acarbose inhibits the reaction [Fructose results in increased expression of CCL2 mRNA]; Acarbose inhibits the reaction [Fructose results in increased expression of CCL2 protein] CTD PMID:17133782 NCBI chr11:81,926,403...81,928,278
Ensembl chr11:81,926,397...81,928,279
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 decreases expression ISO Acarbose results in decreased expression of CYP2E1 mRNA CTD PMID:14975757 NCBI chr 7:140,343,732...140,354,903
Ensembl chr 7:140,343,652...140,354,900
JBrowse link
G Fasn fatty acid synthase decreases expression ISO Acarbose results in decreased expression of FASN mRNA; Acarbose results in decreased expression of FASN protein CTD PMID:8101498 NCBI chr11:120,696,784...120,715,992
Ensembl chr11:120,696,672...120,715,373
JBrowse link
G Ins1 insulin I increases secretion
increases response to substance
decreases secretion
multiple interactions
decreases expression
ISO Acarbose results in increased secretion of INS1 protein
Acarbose results in increased susceptibility to INS1 protein
Acarbose results in decreased secretion of INS1 protein
Acarbose inhibits the reaction [[Dietary Sucrose co-treated with Sodium Chloride, Dietary] results in increased expression of INS1 protein]
Acarbose results in decreased expression of INS1 protein
CTD PMID:1767839 PMID:8101498 PMID:9313782 PMID:18290871 NCBI chr19:52,252,735...52,253,453
Ensembl chr19:52,252,735...52,253,914
JBrowse link
G Lep leptin decreases expression ISO Acarbose results in decreased expression of LEP protein CTD PMID:18290871 NCBI chr 6:29,060,220...29,073,875
Ensembl chr 6:29,060,219...29,073,876
JBrowse link
G Mgam maltase-glucoamylase decreases activity ISO
EXP
Acarbose results in decreased activity of MGAM protein CTD PMID:17585022 PMID:20349118 NCBI chr 6:40,605,765...40,746,057
Ensembl chr 6:40,605,765...40,746,057
JBrowse link
G Npy neuropeptide Y decreases expression ISO Acarbose results in decreased expression of NPY protein CTD PMID:18290871 NCBI chr 6:49,799,690...49,806,487
Ensembl chr 6:49,799,690...49,806,487
JBrowse link
G Ppargc1a peroxisome proliferative activated receptor, gamma, coactivator 1 alpha affects response to substance ISO PPARGC1A protein polymorphism affects the susceptibility to Acarbose CTD PMID:15592662 NCBI chr 5:51,611,591...52,273,316
Ensembl chr 5:51,611,592...51,725,068
JBrowse link
G Slc2a1 solute carrier family 2 (facilitated glucose transporter), member 1 increases expression ISO Acarbose results in increased expression of SLC2A1 protein CTD PMID:11779583 NCBI chr 4:118,966,001...118,994,527
Ensembl chr 4:118,965,908...118,995,180
JBrowse link
G Slc2a4 solute carrier family 2 (facilitated glucose transporter), member 4 increases expression ISO Acarbose results in increased expression of SLC2A4 mRNA; Acarbose results in increased expression of SLC2A4 protein CTD PMID:1767839 NCBI chr11:69,833,112...69,839,040
Ensembl chr11:69,833,365...69,839,014
JBrowse link
G Sqstm1 sequestosome 1 affects response to substance EXP SQSTM1 affects the susceptibility to Acarbose CTD PMID:19207582 NCBI chr11:50,090,979...50,105,303
Ensembl chr11:50,090,193...50,101,654
JBrowse link
G Tnf tumor necrosis factor decreases expression
multiple interactions
EXP
ISO
Acarbose results in decreased expression of TNF mRNA
Acarbose results in decreased expression of TNF mRNA; Acarbose results in decreased expression of TNF protein
Acarbose inhibits the reaction [Oxygen deficiency results in increased expression of TNF mRNA]
CTD PMID:12717270 PMID:14975757 PMID:20703014 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983
JBrowse link
aclacinomycin A term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp1 caspase 1 increases response to substance EXP CASP1 results in increased susceptibility to Aclarubicin CTD PMID:9491796 NCBI chr 9:5,298,517...5,307,281
Ensembl chr 9:5,298,508...5,307,290
JBrowse link
G Casp3 caspase 3 increases activity
multiple interactions
EXP
ISO
Aclarubicin results in increased activity of CASP3 protein
acetyl-aspartyl-glutamyl-valyl-aspartal inhibits the reaction [Aclarubicin results in increased activity of CASP3 protein]
CTD PMID:16215684 PMID:20399885 NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724
JBrowse link
G Casp8 caspase 8 increases activity ISO Aclarubicin results in increased activity of CASP8 protein CTD PMID:20399885 NCBI chr 1:58,834,553...58,886,663
Ensembl chr 1:58,834,533...58,886,662
JBrowse link
G Dffa DNA fragmentation factor, alpha subunit increases degradation ISO Aclarubicin results in increased degradation of DFFA protein CTD PMID:12370496 NCBI chr 4:149,188,599...149,205,110
Ensembl chr 4:149,188,603...149,205,104
JBrowse link
G Gata1 GATA binding protein 1 multiple interactions
increases activity
increases expression
ISO Acetylcysteine inhibits the reaction [Aclarubicin results in increased expression of GATA1 mRNA]; Aclarubicin promotes the reaction [GATA1 protein binds to GSTP1 promoter]; pyrrolidine dithiocarbamic acid inhibits the reaction [Aclarubicin results in increased expression of GATA1 mRNA]; Quercetin inhibits the reaction [Aclarubicin results in increased expression of GATA1 mRNA]
Aclarubicin results in increased activity of GATA1 protein
CTD PMID:10656287 PMID:14623254 NCBI chr  X:7,825,504...7,842,844
Ensembl chr  X:7,825,499...7,844,310
JBrowse link
G Gstp1 glutathione S-transferase, pi 1 multiple interactions
increases expression
ISO Aclarubicin promotes the reaction [GATA1 protein binds to GSTP1 promoter]
Aclarubicin results in increased expression of GSTP1 mRNA; Aclarubicin results in increased expression of GSTP1 protein
CTD PMID:14623254 NCBI chr19:4,085,411...4,087,912
Ensembl chr19:4,085,407...4,087,985
JBrowse link
G Hmbs hydroxymethylbilane synthase increases expression
multiple interactions
ISO Aclarubicin results in increased expression of HMBS mRNA
Acetylcysteine inhibits the reaction [Aclarubicin results in increased expression of HMBS mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Aclarubicin results in increased expression of HMBS mRNA]; Quercetin inhibits the reaction [Aclarubicin results in increased expression of HMBS mRNA]
CTD PMID:10656287 NCBI chr 9:44,247,645...44,255,525
Ensembl chr 9:44,247,636...44,255,525
JBrowse link
G Nfe2 nuclear factor, erythroid derived 2 increases expression
multiple interactions
ISO Aclarubicin results in increased expression of NFE2 mRNA
Acetylcysteine inhibits the reaction [Aclarubicin results in increased expression of NFE2 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Aclarubicin results in increased expression of NFE2 mRNA]; Quercetin inhibits the reaction [Aclarubicin results in increased expression of NFE2 mRNA]
CTD PMID:10656287 NCBI chr15:103,156,640...103,166,809
Ensembl chr15:103,156,639...103,166,830
JBrowse link
G Parp1 poly (ADP-ribose) polymerase family, member 1 affects activity ISO Aclarubicin affects the activity of PARP1 protein CTD PMID:20399885 NCBI chr 1:180,396,456...180,428,564
Ensembl chr 1:180,396,489...180,428,819
JBrowse link
G Slc22a2 solute carrier family 22 (organic cation transporter), member 2 multiple interactions ISO Aclarubicin inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr17:12,803,076...12,847,376
Ensembl chr17:12,803,019...12,847,375
JBrowse link
G Sod1 superoxide dismutase 1, soluble decreases activity ISO Aclarubicin results in decreased activity of SOD1 protein CTD PMID:10656287 NCBI chr16:90,017,650...90,023,221
Ensembl chr16:90,017,642...90,023,217
JBrowse link
G Xiap X-linked inhibitor of apoptosis increases response to substance ISO XIAP protein results in increased susceptibility to Aclarubicin CTD PMID:10815900 NCBI chr  X:41,148,483...41,198,541
Ensembl chr  X:41,148,556...41,198,533
JBrowse link
beta-D-Gal-(1->3)-beta-D-GalNAc-(1->4)-[alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->3)]-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-Cer term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nos2 nitric oxide synthase 2, inducible multiple interactions EXP ganglioside, GD1b analog inhibits the reaction [[lipopolysaccharide, E. coli O26-B6 results in increased activity of NOS2 protein] which results in increased secretion of Nitrites]; ganglioside, GD1b inhibits the reaction [[lipopolysaccharide, E. coli O26-B6 results in increased activity of NOS2 protein] which results in increased secretion of Nitrites] CTD PMID:31202640 NCBI chr11:78,811,613...78,851,052
Ensembl chr11:78,811,613...78,851,080
JBrowse link
digitonin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccnb1 cyclin B1 increases expression EXP Digitonin results in increased expression of CCNB1 protein CTD PMID:36030841 NCBI chr13:100,915,247...100,922,994
Ensembl chr13:100,915,158...100,923,078
JBrowse link
G Ccnd1 cyclin D1 increases expression EXP Digitonin results in increased expression of CCND1 protein CTD PMID:36030841 NCBI chr 7:144,483,668...144,493,568
Ensembl chr 7:144,483,668...144,493,662
JBrowse link
G Cdh5 cadherin 5 multiple interactions ISO Digitonin inhibits the reaction [[ETV2 protein co-treated with GATA2 protein] results in decreased expression of CDH5 protein] CTD PMID:31404653 NCBI chr 8:104,828,247...104,871,136
Ensembl chr 8:104,828,257...104,871,143
JBrowse link
G Cdkn1a cyclin dependent kinase inhibitor 1A decreases expression EXP Digitonin results in decreased expression of CDKN1A protein CTD PMID:36030841 NCBI chr17:29,309,953...29,319,696
Ensembl chr17:29,309,950...29,319,701
JBrowse link
G Cdkn1b cyclin dependent kinase inhibitor 1B decreases expression EXP Digitonin results in decreased expression of CDKN1B protein CTD PMID:36030841 NCBI chr 6:134,897,364...134,902,488
Ensembl chr 6:134,897,364...134,902,476
JBrowse link
G Cyp2b10 cytochrome P450, family 2, subfamily b, polypeptide 10 increases expression EXP Digitonin results in increased expression of CYP2B10 protein CTD PMID:36030841 NCBI chr 7:25,597,083...25,626,049
Ensembl chr 7:25,597,045...25,626,049
JBrowse link
G Cyp3a11 cytochrome P450, family 3, subfamily a, polypeptide 11 increases expression EXP Digitonin results in increased expression of CYP3A11 protein CTD PMID:36030841 NCBI chr 5:145,791,417...145,816,664
Ensembl chr 5:145,791,236...145,816,774
JBrowse link
G Etv2 ets variant 2 multiple interactions ISO Digitonin inhibits the reaction [[ETV2 protein co-treated with GATA2 protein] results in decreased expression of CDH5 protein]; Digitonin inhibits the reaction [[ETV2 protein co-treated with GATA2 protein] results in increased expression of SPN protein] CTD PMID:31404653 NCBI chr 7:30,333,041...30,335,934
Ensembl chr 7:30,333,041...30,335,277
JBrowse link
G Gata2 GATA binding protein 2 multiple interactions ISO Digitonin inhibits the reaction [[ETV2 protein co-treated with GATA2 protein] results in decreased expression of CDH5 protein]; Digitonin inhibits the reaction [[ETV2 protein co-treated with GATA2 protein] results in increased expression of SPN protein] CTD PMID:31404653 NCBI chr 6:88,170,873...88,184,014
Ensembl chr 6:88,170,873...88,184,014
JBrowse link
G Hexb hexosaminidase B multiple interactions
increases activity
EXP 1,2-dioleoyl-sn-glycero-3-phosphoglycerol inhibits the reaction [Digitonin results in increased activity of HEXB protein] CTD PMID:36860548 NCBI chr13:97,312,839...97,334,865
Ensembl chr13:97,312,839...97,334,865
JBrowse link
G Hif1a hypoxia inducible factor 1, alpha subunit decreases expression ISO Digitonin results in decreased expression of HIF1A protein CTD PMID:34717917 NCBI chr12:73,948,186...73,994,304
Ensembl chr12:73,948,149...73,994,304
JBrowse link
G Nek2 NIMA (never in mitosis gene a)-related expressed kinase 2 increases expression EXP Digitonin results in increased expression of NEK2 protein CTD PMID:36030841 NCBI chr 1:191,553,622...191,565,161
Ensembl chr 1:191,553,556...191,565,162
JBrowse link
G Rbl2 RB transcriptional corepressor like 2 decreases expression EXP Digitonin results in decreased expression of RBL2 protein CTD PMID:36030841 NCBI chr 8:91,796,685...91,850,472
Ensembl chr 8:91,796,685...91,850,472
JBrowse link
G Slc22a2 solute carrier family 22 (organic cation transporter), member 2 multiple interactions ISO Digitonin inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr17:12,803,076...12,847,376
Ensembl chr17:12,803,019...12,847,375
JBrowse link
G Slco1a4 solute carrier organic anion transporter family, member 1a4 increases expression EXP Digitonin results in increased expression of SLCO1A4 protein CTD PMID:36030841 NCBI chr 6:141,751,164...141,802,011
Ensembl chr 6:141,751,166...141,801,925
JBrowse link
G Spn sialophorin multiple interactions ISO Digitonin inhibits the reaction [[ETV2 protein co-treated with GATA2 protein] results in increased expression of SPN protein] CTD PMID:31404653 NCBI chr 7:126,731,404...126,743,785
Ensembl chr 7:126,731,404...126,736,995
JBrowse link
dioscin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb11 ATP-binding cassette, sub-family B member 11 multiple interactions ISO dioscin promotes the reaction [1-Naphthylisothiocyanate results in increased expression of ABCB11 mRNA]; dioscin promotes the reaction [1-Naphthylisothiocyanate results in increased expression of ABCB11 protein] CTD PMID:27317372 NCBI chr 2:69,068,626...69,172,960
Ensembl chr 2:69,068,626...69,172,958
JBrowse link
G Abcb1a ATP-binding cassette, sub-family B member 1A decreases expression ISO dioscin results in decreased expression of ABCB1 mRNA; dioscin results in decreased expression of ABCB1 protein CTD PMID:24680847 NCBI chr 5:8,617,091...8,798,575
Ensembl chr 5:8,710,077...8,798,575
JBrowse link
G Abcc2 ATP-binding cassette, sub-family member 2 multiple interactions ISO dioscin promotes the reaction [1-Naphthylisothiocyanate results in increased expression of ABCC2 mRNA]; dioscin promotes the reaction [1-Naphthylisothiocyanate results in increased expression of ABCC2 protein] CTD PMID:27317372 NCBI chr19:43,770,747...43,826,771
Ensembl chr19:43,770,631...43,829,179
JBrowse link
G Acadm acyl-Coenzyme A dehydrogenase, medium chain multiple interactions ISO
EXP
dioscin inhibits the reaction [Ethanol results in decreased expression of ACADM protein] CTD PMID:24146112 NCBI chr 3:153,627,990...153,650,280
Ensembl chr 3:153,627,994...153,650,269
JBrowse link
G Acads acyl-Coenzyme A dehydrogenase, short chain multiple interactions EXP
ISO
dioscin inhibits the reaction [Ethanol results in decreased expression of ACADS protein] CTD PMID:24146112 NCBI chr 5:115,248,358...115,257,405
Ensembl chr 5:115,248,358...115,257,405
JBrowse link
G Acox1 acyl-Coenzyme A oxidase 1, palmitoyl multiple interactions ISO
EXP
dioscin inhibits the reaction [Ethanol results in decreased expression of ACOX1 mRNA] CTD PMID:24146112 NCBI chr11:116,062,714...116,089,605
Ensembl chr11:116,062,714...116,089,871
JBrowse link
G Acsl1 acyl-CoA synthetase long-chain family member 1 multiple interactions EXP
ISO
dioscin inhibits the reaction [Ethanol results in decreased expression of ACSL1 protein] CTD PMID:24146112 NCBI chr 8:46,924,214...46,989,088
Ensembl chr 8:46,924,074...46,989,088
JBrowse link
G Acsl5 acyl-CoA synthetase long-chain family member 5 multiple interactions EXP
ISO
dioscin inhibits the reaction [Ethanol results in decreased expression of ACSL5 protein] CTD PMID:24146112 NCBI chr19:55,240,298...55,285,060
Ensembl chr19:55,240,370...55,286,152
JBrowse link
G Acta2 actin alpha 2, smooth muscle, aorta multiple interactions EXP dioscin inhibits the reaction [[Ovalbumin co-treated with Aluminum Hydroxide] results in increased expression of ACTA2 protein] CTD PMID:35481609 NCBI chr19:34,217,736...34,232,985
Ensembl chr19:34,218,490...34,232,990
JBrowse link
G Akt1 thymoma viral proto-oncogene 1 multiple interactions
decreases expression
ISO
EXP
dioscin inhibits the reaction [TGFB1 protein results in increased phosphorylation of AKT1 protein]; dioscin inhibits the reaction [VEGFA protein results in increased phosphorylation of AKT1 protein]
dioscin inhibits the reaction [[Ovalbumin co-treated with Aluminum Hydroxide] results in increased phosphorylation of AKT1 protein]
dioscin results in decreased expression of AKT1 mRNA
CTD PMID:25111127 PMID:29990575 PMID:35481609 NCBI chr12:112,620,260...112,641,266
Ensembl chr12:112,620,255...112,641,318
JBrowse link
G Aldh7a1 aldehyde dehydrogenase family 7, member A1 multiple interactions EXP
ISO
dioscin inhibits the reaction [Ethanol results in decreased expression of ALDH7A1 protein] CTD PMID:24146112 NCBI chr18:56,657,794...56,706,112
Ensembl chr18:56,642,759...56,706,023
JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 decreases expression ISO dioscin results in decreased expression of APAF1 mRNA CTD PMID:33359023 NCBI chr10:90,825,173...90,918,688
Ensembl chr10:90,825,173...90,918,632
JBrowse link
G Atf6 activating transcription factor 6 multiple interactions ISO
EXP
dioscin inhibits the reaction [Ethanol results in increased expression of ATF6 protein] CTD PMID:24146112 NCBI chr 1:170,532,026...170,696,414
Ensembl chr 1:170,532,243...170,695,340
JBrowse link
G Bad BCL2-associated agonist of cell death increases expression ISO dioscin results in increased expression of BAD mRNA CTD PMID:33359023 NCBI chr19:6,919,229...6,929,273
Ensembl chr19:6,919,229...6,929,267
JBrowse link
G Bak1 BCL2-antagonist/killer 1 multiple interactions
increases expression
EXP
ISO
dioscin inhibits the reaction [Acetaminophen results in increased expression of BAK1 protein]
dioscin results in increased expression of BAK1 mRNA; dioscin results in increased expression of BAK1 protein
CTD PMID:22334414 PMID:22939915 PMID:29990575 PMID:33359023 NCBI chr17:27,238,786...27,247,601
Ensembl chr17:27,238,784...27,247,983
JBrowse link
G Bax BCL2-associated X protein multiple interactions
increases expression
EXP
ISO
dioscin inhibits the reaction [Acetaminophen results in increased expression of BAX protein]
dioscin results in increased expression of BAX mRNA; dioscin results in increased expression of BAX protein
CTD PMID:22334414 PMID:22939915 PMID:33359023 NCBI chr 7:45,111,124...45,116,332
Ensembl chr 7:45,111,121...45,116,322
JBrowse link
G Bbc3 BCL2 binding component 3 increases expression ISO dioscin results in increased expression of BBC3 mRNA; dioscin results in increased expression of BBC3 protein CTD PMID:29990575 PMID:33359023 NCBI chr 7:16,042,307...16,052,130
Ensembl chr 7:16,042,318...16,052,130
JBrowse link
G Bcl2 B cell leukemia/lymphoma 2 multiple interactions
decreases expression
increases expression
EXP
ISO
dioscin inhibits the reaction [Acetaminophen results in decreased expression of BCL2 protein]
dioscin results in decreased expression of BCL2 mRNA; dioscin results in decreased expression of BCL2 protein
dioscin results in increased expression of BCL2 protein
CTD PMID:22334414 PMID:22939915 PMID:24742230 PMID:29990575 PMID:33359023 NCBI chr 1:106,465,906...106,642,020
Ensembl chr 1:106,465,908...106,642,004
JBrowse link
G Bcl2l1 BCL2-like 1 decreases expression ISO dioscin results in decreased expression of BCL2L1 mRNA; dioscin results in decreased expression of BCL2L1 protein CTD PMID:22334414 PMID:29990575 PMID:33359023 NCBI chr 2:152,600,652...152,673,632
Ensembl chr 2:152,622,588...152,673,648
JBrowse link
G Bid BH3 interacting domain death agonist multiple interactions
decreases expression
EXP
ISO
[Acetaminophen co-treated with dioscin] results in increased expression of BID protein
dioscin results in decreased expression of BID mRNA; dioscin results in decreased expression of BID protein
CTD PMID:22334414 PMID:22939915 NCBI chr 6:120,870,080...120,894,074
Ensembl chr 6:120,868,891...120,893,814
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 increases expression ISO dioscin results in increased expression of BIRC5 mRNA CTD PMID:29990575 NCBI chr11:117,740,063...117,746,569
Ensembl chr11:117,740,077...117,746,569
JBrowse link
G Casp3 caspase 3 multiple interactions
decreases expression
increases expression
increases activity
ISO
EXP
dioscin inhibits the reaction [Ethanol results in increased expression of CASP3 protein]
dioscin results in decreased expression of CASP3 mRNA; dioscin results in decreased expression of CASP3 protein
benzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone inhibits the reaction [dioscin results in increased expression of CASP3 protein]; benzyloxycarbonyl-leucyl-glutamyl-histidyl-aspartic acid fluoromethyl ketone inhibits the reaction [dioscin results in increased expression of CASP3 protein]
dioscin results in increased expression of CASP3 mRNA; dioscin results in increased expression of CASP3 protein
dioscin results in increased activity of CASP3 protein
CTD PMID:22334414 PMID:24146112 PMID:29990575 PMID:33359023 NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724
JBrowse link
G Casp7 caspase 7 increases expression ISO dioscin results in increased expression of CASP7 mRNA CTD PMID:29990575 NCBI chr19:56,382,640...56,430,780
Ensembl chr19:56,385,561...56,430,776
JBrowse link
G Casp8 caspase 8 increases activity
decreases expression
multiple interactions
increases expression
ISO dioscin results in increased activity of CASP8 protein
dioscin results in decreased expression of CASP8 mRNA
dioscin results in decreased expression of and results in increased cleavage of CASP8 protein
dioscin results in increased expression of CASP8 mRNA; dioscin results in increased expression of CASP8 protein
CTD PMID:22334414 PMID:29990575 PMID:33359023 NCBI chr 1:58,834,553...58,886,663
Ensembl chr 1:58,834,533...58,886,662
JBrowse link
G Casp9 caspase 9 multiple interactions
decreases expression
increases expression
ISO
EXP
dioscin inhibits the reaction [Ethanol results in increased expression of CASP9 protein]
dioscin results in decreased expression of CASP9 mRNA; dioscin results in decreased expression of CASP9 protein
dioscin results in increased expression of CASP9 mRNA; dioscin results in increased expression of CASP9 protein
CTD PMID:24146112 PMID:29990575 PMID:33359023 NCBI chr 4:141,520,923...141,543,289
Ensembl chr 4:141,520,923...141,543,287
JBrowse link
G Ccna2 cyclin A2 decreases expression ISO dioscin results in decreased expression of CCNA2 mRNA; dioscin results in decreased expression of CCNA2 protein CTD PMID:33359023 NCBI chr 3:36,619,014...36,627,187
Ensembl chr 3:36,619,014...36,626,299
JBrowse link
G Ccnb1 cyclin B1 decreases expression ISO dioscin results in decreased expression of CCNB1 mRNA; dioscin results in decreased expression of CCNB1 protein CTD PMID:29990575 NCBI chr13:100,915,247...100,922,994
Ensembl chr13:100,915,158...100,923,078
JBrowse link
G Ccnd1 cyclin D1 increases expression
decreases expression
ISO dioscin results in increased expression of CCND1 mRNA
dioscin results in decreased expression of CCND1 mRNA; dioscin results in decreased expression of CCND1 protein
CTD PMID:29990575 PMID:33359023 NCBI chr 7:144,483,668...144,493,568
Ensembl chr 7:144,483,668...144,493,662
JBrowse link
G Ccne1 cyclin E1 decreases expression ISO dioscin results in decreased expression of CCNE1 mRNA; dioscin results in decreased expression of CCNE1 protein CTD PMID:33359023 NCBI chr 7:37,797,409...37,806,915
Ensembl chr 7:37,797,409...37,806,959
JBrowse link
G Cdk1 cyclin dependent kinase 1 decreases expression ISO dioscin results in decreased expression of CDK1 mRNA; dioscin results in decreased expression of CDK1 protein CTD PMID:29990575 NCBI chr10:69,170,976...69,188,742
Ensembl chr10:69,170,976...69,188,768
JBrowse link
G Cdk2 cyclin dependent kinase 2 decreases expression ISO dioscin results in decreased expression of CDK2 mRNA; dioscin results in decreased expression of CDK2 protein CTD PMID:33359023 NCBI chr10:128,533,807...128,540,920
Ensembl chr10:128,533,808...128,540,900
JBrowse link
G Cdk4 cyclin dependent kinase 4 decreases expression ISO dioscin results in decreased expression of CDK4 mRNA CTD PMID:33359023 NCBI chr10:126,899,404...126,903,157
Ensembl chr10:126,899,403...126,903,789
JBrowse link
G Cdk6 cyclin dependent kinase 6 decreases expression ISO dioscin results in decreased expression of CDK6 mRNA; dioscin results in decreased expression of CDK6 protein CTD PMID:33359023 NCBI chr 5:3,391,004...3,581,008
Ensembl chr 5:3,391,485...3,581,008
JBrowse link
G Cdkn1a cyclin dependent kinase inhibitor 1A increases expression ISO dioscin results in increased expression of CDKN1A mRNA; dioscin results in increased expression of CDKN1A protein CTD PMID:29990575 PMID:33359023 NCBI chr17:29,309,953...29,319,696
Ensembl chr17:29,309,950...29,319,701
JBrowse link
G Cdkn1b cyclin dependent kinase inhibitor 1B increases expression ISO dioscin results in increased expression of CDKN1B mRNA; dioscin results in increased expression of CDKN1B protein CTD PMID:33359023 NCBI chr 6:134,897,364...134,902,488
Ensembl chr 6:134,897,364...134,902,476
JBrowse link
G Cdkn2a cyclin dependent kinase inhibitor 2A increases expression ISO dioscin results in increased expression of CDKN2A mRNA; dioscin results in increased expression of CDKN2A protein CTD PMID:33359023 NCBI chr 4:89,192,710...89,212,856
Ensembl chr 4:89,192,708...89,212,890
JBrowse link
G Chek1 checkpoint kinase 1 decreases expression ISO dioscin results in decreased expression of CHEK1 mRNA; dioscin results in decreased expression of CHEK1 protein CTD PMID:33359023 NCBI chr 9:36,619,935...36,637,897
Ensembl chr 9:36,619,778...36,638,361
JBrowse link
G Chek2 checkpoint kinase 2 decreases expression ISO dioscin results in decreased expression of CHEK2 mRNA; dioscin results in decreased expression of CHEK2 protein CTD PMID:29990575 NCBI chr 5:110,987,668...111,022,006
Ensembl chr 5:110,987,845...111,022,011
JBrowse link
G Cpt1a carnitine palmitoyltransferase 1a, liver multiple interactions EXP
ISO
dioscin inhibits the reaction [Ethanol results in decreased expression of CPT1A mRNA] CTD PMID:24146112 NCBI chr19:3,372,328...3,435,735
Ensembl chr19:3,372,334...3,435,733
JBrowse link
G Ctnnb1 catenin beta 1 multiple interactions
increases expression
EXP
ISO
fulvestrant inhibits the reaction [dioscin results in increased expression of CTNNB1 mRNA]
dioscin results in increased expression of CTNNB1 protein
dioscin results in increased expression of CTNNB1 mRNA; dioscin results in increased expression of CTNNB1 protein
CTD PMID:24742230 NCBI chr 9:120,762,466...120,789,573
Ensembl chr 9:120,758,282...120,789,573
JBrowse link
G Cycs cytochrome c, somatic increases expression ISO dioscin results in increased expression of CYCS mRNA CTD PMID:33359023 NCBI chr 6:50,539,543...50,543,549
Ensembl chr 6:50,539,543...50,543,518
JBrowse link
G Cyp2c65 cytochrome P450, family 2, subfamily c, polypeptide 65 increases expression ISO dioscin results in increased expression of CYP2C9 mRNA CTD PMID:29990575 NCBI chr19:39,049,450...39,082,392
Ensembl chr19:39,049,459...39,082,388
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions EXP
ISO
dioscin inhibits the reaction [Acetaminophen results in increased expression of and results in increased activity of CYP2E1 protein]; dioscin inhibits the reaction [Ethanol results in increased expression of and results in increased activity of CYP2E1 protein] CTD PMID:22939915 PMID:24146112 NCBI chr 7:140,343,732...140,354,903
Ensembl chr 7:140,343,652...140,354,900
JBrowse link
G Dgat1 diacylglycerol O-acyltransferase 1 multiple interactions EXP
ISO
dioscin inhibits the reaction [Ethanol results in increased expression of DGAT1 mRNA] CTD PMID:24146112 NCBI chr15:76,386,215...76,396,167
Ensembl chr15:76,386,215...76,396,153
JBrowse link
G Dgat2 diacylglycerol O-acyltransferase 2 multiple interactions EXP
ISO
dioscin inhibits the reaction [Ethanol results in increased expression of DGAT2 mRNA] CTD PMID:24146112 NCBI chr 7:98,802,870...98,831,920
Ensembl chr 7:98,802,865...98,831,926
JBrowse link
G Diablo diablo, IAP-binding mitochondrial protein increases expression ISO dioscin results in increased expression of DIABLO mRNA CTD PMID:29990575 NCBI chr 5:123,649,393...123,664,825
Ensembl chr 5:123,647,828...123,662,239
JBrowse link
G Esr1 estrogen receptor 1 (alpha) increases expression
multiple interactions
EXP
ISO
dioscin results in increased expression of ESR1 protein
fulvestrant inhibits the reaction [dioscin results in increased expression of ESR1 protein]
CTD PMID:24742230 NCBI chr10:4,561,989...4,955,633
Ensembl chr10:4,561,593...4,955,614
JBrowse link
G Esr2 estrogen receptor 2 (beta) increases expression
multiple interactions
ISO
EXP
dioscin results in increased expression of ESR2 protein
fulvestrant inhibits the reaction [dioscin results in increased expression of ESR2 protein]
CTD PMID:24742230 NCBI chr12:76,167,193...76,224,033
Ensembl chr12:76,167,193...76,224,033
JBrowse link
G Fadd Fas associated via death domain increases expression ISO dioscin results in increased expression of FADD mRNA; dioscin results in increased expression of FADD protein CTD PMID:22334414 PMID:29990575 PMID:33359023 NCBI chr 7:144,132,060...144,136,178
Ensembl chr 7:144,131,055...144,136,200
JBrowse link
G Fas Fas cell surface death receptor increases expression ISO dioscin results in increased expression of FAS mRNA; dioscin results in increased expression of FAS protein CTD PMID:22334414 PMID:33359023 NCBI chr19:34,267,926...34,305,175
Ensembl chr19:34,268,066...34,305,172
JBrowse link
G Fasl Fas ligand increases expression ISO dioscin results in increased expression of FASLG mRNA; dioscin results in increased expression of FASLG protein CTD PMID:22334414 PMID:29990575 NCBI chr 1:161,608,260...161,616,064
Ensembl chr 1:161,608,258...161,616,064
JBrowse link
G Foxo1 forkhead box O1 increases expression ISO dioscin results in increased expression of FOXO1 mRNA CTD PMID:33359023 NCBI chr 3:52,175,758...52,257,530
Ensembl chr 3:52,175,757...52,260,642
JBrowse link
G Gpt glutamic pyruvic transaminase, soluble multiple interactions ISO dioscin inhibits the reaction [1-Naphthylisothiocyanate results in increased expression of GPT protein] CTD PMID:27317372 NCBI chr15:76,580,926...76,583,875
Ensembl chr15:76,579,916...76,583,886
JBrowse link
G Gsr glutathione reductase multiple interactions ISO
EXP
dioscin inhibits the reaction [Ethanol results in decreased expression of GSR protein] CTD PMID:24146112 NCBI chr 8:34,143,266...34,188,190
Ensembl chr 8:34,142,551...34,188,191
JBrowse link
G Hmgb1 high mobility group box 1 multiple interactions ISO
EXP
dioscin inhibits the reaction [Doxorubicin results in increased expression of HMGB1 protein]
dioscin inhibited the reaction [thioacetamide increased expression of Hmgb1 protein in liver]
CTD
RGD
PMID:28082111 PMID:29091898 RGD:15090820 NCBI chr 5:148,983,512...148,989,867
Ensembl chr 5:148,983,512...149,121,299
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions ISO
EXP
dioscin inhibits the reaction [Doxorubicin results in decreased expression of HMOX1 protein]
dioscin inhibited the reaction [thioacetamide decreased expression of Hmox1 protein in liver]
CTD
RGD
PMID:28082111 PMID:29091898 RGD:15090820 NCBI chr 8:75,820,246...75,827,221
Ensembl chr 8:75,820,249...75,827,217
JBrowse link
G Hspa5 heat shock protein 5 multiple interactions ISO
EXP
dioscin inhibits the reaction [Ethanol results in increased expression of HSPA5 protein] CTD PMID:24146112 NCBI chr 2:34,662,102...34,666,541
Ensembl chr 2:34,661,982...34,667,559
JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions EXP dioscin inhibited the reaction [thioacetamide increased expression of Icam1 protein in liver] RGD PMID:29091898 RGD:15090820 NCBI chr 9:20,927,236...20,940,110
Ensembl chr 9:20,927,281...20,940,113
JBrowse link
G Il13 interleukin 13 multiple interactions EXP dioscin inhibits the reaction [[Ovalbumin co-treated with Aluminum Hydroxide] results in increased expression of IL13 protein] CTD PMID:35481609 NCBI chr11:53,522,150...53,525,529
Ensembl chr11:53,522,151...53,525,529
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO
EXP
dioscin inhibits the reaction [Doxorubicin results in increased expression of IL1B mRNA]; NR1H4 protein affects the reaction [dioscin inhibits the reaction [Doxorubicin results in increased expression of IL1B mRNA]]
dioscin inhibited the reaction [thioacetamide increased expression of IL-1b mRNA in liver]
CTD
RGD
PMID:28082111 PMID:29091898 RGD:15090820 NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059
JBrowse link
G Il4 interleukin 4 multiple interactions EXP dioscin inhibits the reaction [[Ovalbumin co-treated with Aluminum Hydroxide] results in increased expression of IL4 protein] CTD PMID:35481609 NCBI chr11:53,503,287...53,509,492
Ensembl chr11:53,493,809...53,509,496
JBrowse link
G Il5 interleukin 5 multiple interactions EXP dioscin inhibits the reaction [[Ovalbumin co-treated with Aluminum Hydroxide] results in increased expression of IL5 protein] CTD PMID:35481609 NCBI chr11:53,611,621...53,615,930
Ensembl chr11:53,611,621...53,615,933
JBrowse link
G Il6 interleukin 6 multiple interactions EXP
ISO
dioscin inhibits the reaction [Ethanol results in increased expression of IL6 mRNA]
dioscin inhibited the reaction [thioacetamide increased expression of IL-6 mRNA in liver]
dioscin inhibits the reaction [Doxorubicin results in increased expression of IL6 mRNA]; dioscin inhibits the reaction [Ethanol results in increased expression of IL6 mRNA]; NR1H4 protein affects the reaction [dioscin inhibits the reaction [Doxorubicin results in increased expression of IL6 mRNA]]
CTD
RGD
PMID:24146112 PMID:28082111 PMID:29091898 RGD:15090820 NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979
JBrowse link
G Kdr kinase insert domain protein receptor multiple interactions ISO dioscin inhibits the reaction [VEGFA protein results in increased phosphorylation of KDR protein] CTD PMID:25111127 NCBI chr 5:76,093,487...76,139,880
Ensembl chr 5:76,093,487...76,139,118
JBrowse link
G Keap1 kelch-like ECH-associated protein 1 multiple interactions ISO dioscin inhibits the reaction [Doxorubicin results in increased expression of KEAP1 protein] CTD PMID:28082111 NCBI chr 9:21,141,026...21,150,628
Ensembl chr 9:21,141,026...21,150,657
JBrowse link
G Krt18 keratin 18 multiple interactions EXP
ISO
dioscin inhibits the reaction [Acetaminophen results in increased expression of KRT18 protein]; dioscin inhibits the reaction [Ethanol results in increased expression of KRT18 protein] CTD PMID:22939915 PMID:24146112 NCBI chr15:101,936,651...101,940,461
Ensembl chr15:101,936,615...101,940,462
JBrowse link
G Lrp5 low density lipoprotein receptor-related protein 5 multiple interactions
increases expression
EXP fulvestrant inhibits the reaction [dioscin results in increased expression of LRP5 mRNA]; LRP5 protein affects the reaction [dioscin results in increased expression of TNFRSF11B mRNA]; LRP5 protein affects the reaction [dioscin results in increased expression of TNFSF11 mRNA] CTD PMID:24742230 NCBI chr19:3,634,825...3,736,574
Ensembl chr19:3,634,828...3,736,564
JBrowse link
G Mapk1 mitogen-activated protein kinase 1 multiple interactions ISO
EXP
dioscin inhibits the reaction [Ethanol results in increased phosphorylation of MAPK1 protein]
dioscin inhibits the reaction [VEGFA protein results in increased phosphorylation of MAPK1 protein]
CTD PMID:24146112 PMID:25111127 NCBI chr16:16,801,246...16,865,317
Ensembl chr16:16,801,246...16,865,317
JBrowse link
G Mapk3 mitogen-activated protein kinase 3 multiple interactions ISO
EXP
dioscin inhibits the reaction [Ethanol results in increased phosphorylation of MAPK3 protein]
dioscin inhibits the reaction [VEGFA protein results in increased phosphorylation of MAPK3 protein]
CTD PMID:24146112 PMID:25111127 NCBI chr 7:126,358,798...126,364,988
Ensembl chr 7:126,358,773...126,364,991
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 increases expression ISO dioscin results in increased expression of MAPK8 mRNA CTD PMID:29990575 NCBI chr14:33,099,855...33,169,213
Ensembl chr14:33,099,855...33,169,115
JBrowse link
G Mapk9 mitogen-activated protein kinase 9 increases expression ISO dioscin results in increased expression of MAPK9 mRNA CTD PMID:29990575 NCBI chr11:49,737,558...49,777,248
Ensembl chr11:49,737,578...49,777,248
JBrowse link
G Mdh1 malate dehydrogenase 1, NAD (soluble) multiple interactions EXP dioscin inhibits the reaction [Acetaminophen results in decreased expression of MDH1 protein] CTD PMID:22939915 NCBI chr11:21,506,692...21,521,934
Ensembl chr11:21,506,692...21,522,367
JBrowse link
G Mtor mechanistic target of rapamycin kinase decreases expression ISO dioscin results in decreased expression of MTOR mRNA CTD PMID:29990575 NCBI chr 4:148,533,039...148,642,142
Ensembl chr 4:148,533,068...148,642,140
JBrowse link
G Muc5ac mucin 5, subtypes A and C, tracheobronchial/gastric multiple interactions EXP dioscin inhibits the reaction [[Ovalbumin co-treated with Aluminum Hydroxide] results in increased expression of MUC5AC mRNA] CTD PMID:35481609 NCBI chr 7:141,342,695...141,372,964
Ensembl chr 7:141,342,709...141,372,968
JBrowse link
G Nfe2l2 nuclear factor, erythroid derived 2, like 2 multiple interactions ISO
EXP
dioscin inhibits the reaction [Doxorubicin results in decreased expression of and affects the localization of NFE2L2 protein]; NR1H4 protein affects the reaction [dioscin inhibits the reaction [Doxorubicin results in decreased expression of NFE2L2 protein]]
dioscin inhibited the reaction [thioacetamide decreased expression of Nfe2L2 protein in liver]
CTD
RGD
PMID:28082111 PMID:29091898 RGD:15090820 NCBI chr 2:75,505,860...75,535,007
Ensembl chr 2:75,505,857...75,534,985
JBrowse link
G Nfkb1 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 multiple interactions EXP dioscin inhibited the reaction [thioacetamide increased expression of Nfkb1 protein in liver] RGD PMID:29091898 RGD:15090820 NCBI chr 3:135,290,416...135,397,422
Ensembl chr 3:135,290,416...135,397,308
JBrowse link
G Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha decreases degradation ISO dioscin results in decreased degradation of NFKBIA protein CTD PMID:24680847 NCBI chr12:55,536,194...55,539,432
Ensembl chr12:55,536,195...55,539,432
JBrowse link
G Nqo1 NAD(P)H dehydrogenase, quinone 1 multiple interactions EXP dioscin inhibited the reaction [thioacetamide decreased expression of Nqo1 protein in liver] RGD PMID:29091898 RGD:15090820 NCBI chr 8:108,114,856...108,139,012
Ensembl chr 8:108,114,857...108,129,838
JBrowse link
G Nr0b2 nuclear receptor subfamily 0, group B, member 2 multiple interactions
increases expression
ISO dioscin promotes the reaction [1-Naphthylisothiocyanate results in increased expression of NR0B2 mRNA]
dioscin results in increased expression of NR0B2 mRNA
CTD PMID:27317372 NCBI chr 4:133,280,687...133,283,997
Ensembl chr 4:133,280,687...133,283,847
JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 multiple interactions ISO dioscin inhibits the reaction [Doxorubicin results in decreased expression of NR1H4 protein]; NR1H4 protein affects the reaction [dioscin inhibits the reaction [Doxorubicin results in decreased expression of NFE2L2 protein]]; NR1H4 protein affects the reaction [dioscin inhibits the reaction [Doxorubicin results in increased expression of IL1B mRNA]]; NR1H4 protein affects the reaction [dioscin inhibits the reaction [Doxorubicin results in increased expression of IL6 mRNA]]; NR1H4 protein affects the reaction [dioscin inhibits the reaction [Doxorubicin results in increased expression of RELA protein]]; NR1H4 protein affects the reaction [dioscin inhibits the reaction [Doxorubicin results in increased expression of TNF mRNA]]
dioscin inhibited the reaction [thioacetamide decreased expression of Nr1h4 protein in liver]
CTD
RGD
PMID:28082111 PMID:29091898 RGD:15090820 NCBI chr10:89,290,096...89,369,484
Ensembl chr10:89,290,096...89,369,447
JBrowse link
G Parp1 poly (ADP-ribose) polymerase family, member 1 multiple interactions
decreases expression
increases expression
EXP
ISO
dioscin inhibits the reaction [Ethanol results in increased expression of PARP1 protein]
dioscin results in decreased expression of PARP1 mRNA; dioscin results in decreased expression of PARP1 protein
dioscin results in increased expression of PARP1 mRNA
CTD PMID:24146112 PMID:29990575 PMID:33359023 NCBI chr 1:180,396,456...180,428,564
Ensembl chr 1:180,396,489...180,428,819
JBrowse link
G Pik3cb phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta decreases expression ISO dioscin results in decreased expression of PIK3CB mRNA CTD PMID:29990575 NCBI chr 9:98,920,455...99,022,264
Ensembl chr 9:98,918,707...99,022,674
JBrowse link
G Pnp2 purine-nucleoside phosphorylase 2 multiple interactions EXP dioscin inhibits the reaction [Acetaminophen results in decreased expression of PNP protein] CTD PMID:22939915 NCBI chr14:51,193,598...51,202,206
Ensembl chr14:51,193,449...51,202,206
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions ISO
EXP
dioscin inhibits the reaction [Ethanol results in decreased expression of PPARA protein] CTD PMID:24146112 NCBI chr15:85,619,112...85,691,052
Ensembl chr15:85,619,184...85,687,020
JBrowse link
G Prdx1 peroxiredoxin 1 multiple interactions EXP dioscin inhibits the reaction [Acetaminophen results in decreased expression of PRDX1 protein] CTD PMID:22939915 NCBI chr 4:116,542,796...116,557,196
Ensembl chr 4:116,542,741...116,558,019
JBrowse link
G Prkaa1 protein kinase, AMP-activated, alpha 1 catalytic subunit multiple interactions EXP dioscin inhibited the reaction [thioacetamide decreased expression of Prkaa1 protein in liver] RGD PMID:29091898 RGD:15090820 NCBI chr15:5,172,641...5,211,380
Ensembl chr15:5,173,343...5,211,380
JBrowse link
G Prkab1 protein kinase, AMP-activated, beta 1 non-catalytic subunit increases expression ISO dioscin results in increased expression of PRKAB1 mRNA CTD PMID:29990575 NCBI chr 5:116,151,654...116,162,449
Ensembl chr 5:116,151,645...116,162,567
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions EXP dioscin inhibited the reaction [thioacetamide increased expression of Ptgs2 protein in liver] RGD PMID:29091898 RGD:15090820 NCBI chr 1:149,975,851...149,983,978
Ensembl chr 1:149,975,782...149,983,978
JBrowse link
G Ptk2 PTK2 protein tyrosine kinase 2 multiple interactions ISO dioscin inhibits the reaction [VEGFA protein results in increased phosphorylation of PTK2 protein] CTD PMID:25111127 NCBI chr15:73,076,951...73,297,192
Ensembl chr15:73,076,951...73,295,129
JBrowse link
G Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) multiple interactions ISO dioscin inhibits the reaction [Doxorubicin results in increased expression of RELA protein]; NR1H4 protein affects the reaction [dioscin inhibits the reaction [Doxorubicin results in increased expression of RELA protein]] CTD PMID:28082111 NCBI chr19:5,686,993...5,698,162
Ensembl chr19:5,687,511...5,698,158
JBrowse link
G Rgn regucalcin multiple interactions EXP dioscin inhibits the reaction [Acetaminophen results in decreased expression of RGN protein] CTD PMID:22939915 NCBI chr  X:20,413,980...20,428,328
Ensembl chr  X:20,416,026...20,428,328
JBrowse link
G Rps6kb1 ribosomal protein S6 kinase, polypeptide 1 decreases expression ISO dioscin results in decreased expression of RPS6KB1 mRNA CTD PMID:29990575 NCBI chr11:86,389,695...86,435,711
Ensembl chr11:86,389,697...86,435,631
JBrowse link
G Slc10a1 solute carrier family 10 (sodium/bile acid cotransporter family), member 1 multiple interactions ISO dioscin inhibits the reaction [1-Naphthylisothiocyanate results in decreased expression of SLC10A1 mRNA] CTD PMID:27317372 NCBI chr12:80,999,959...81,015,479
Ensembl chr12:80,999,957...81,015,479
JBrowse link
G Slco1a4 solute carrier organic anion transporter family, member 1a4 increases expression ISO dioscin results in increased expression of SLCO1A2 mRNA CTD PMID:27317372 NCBI chr 6:141,751,164...141,802,011
Ensembl chr 6:141,751,166...141,801,925
JBrowse link
G Slco1b2 solute carrier organic anion transporter family, member 1b2 multiple interactions
increases expression
ISO dioscin inhibits the reaction [1-Naphthylisothiocyanate results in decreased expression of SLCO1B2 mRNA]; dioscin inhibits the reaction [1-Naphthylisothiocyanate results in decreased expression of SLCO1B2 protein]
dioscin results in increased expression of SLCO1B2 mRNA
CTD PMID:27317372 NCBI chr 6:141,575,178...141,632,372
Ensembl chr 6:141,575,244...141,632,372
JBrowse link
G Src Rous sarcoma oncogene multiple interactions ISO dioscin inhibits the reaction [VEGFA protein results in increased phosphorylation of SRC protein] CTD PMID:25111127 NCBI chr 2:157,265,828...157,313,758
Ensembl chr 2:157,260,364...157,313,782
JBrowse link
G Suox sulfite oxidase multiple interactions EXP dioscin inhibits the reaction [Acetaminophen results in decreased expression of SUOX protein] CTD PMID:22939915 NCBI chr10:128,505,756...128,509,787
Ensembl chr10:128,505,763...128,509,942
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions EXP
ISO
dioscin inhibits the reaction [[Ovalbumin co-treated with Aluminum Hydroxide] results in increased expression of TGFB1 protein]
dioscin inhibits the reaction [TGFB1 protein results in increased phosphorylation of AKT1 protein]
CTD PMID:35481609 NCBI chr 7:25,386,406...25,404,503
Ensembl chr 7:25,386,427...25,404,502
JBrowse link
G Tnf tumor necrosis factor multiple interactions
increases expression
EXP
ISO
dioscin inhibits the reaction [[Ovalbumin co-treated with Aluminum Hydroxide] results in increased expression of TNF protein]; dioscin inhibits the reaction [Ethanol results in increased expression of TNF mRNA]
dioscin inhibited the reaction [thioacetamide increased expression of Tnfa mRNA in liver]
dioscin results in increased expression of TNF mRNA; dioscin results in increased expression of TNF protein
dioscin inhibits the reaction [Doxorubicin results in increased expression of TNF mRNA]; dioscin inhibits the reaction [Ethanol results in increased expression of TNF mRNA]; NR1H4 protein affects the reaction [dioscin inhibits the reaction [Doxorubicin results in increased expression of TNF mRNA]]
CTD
RGD
PMID:22334414 PMID:24146112 PMID:28082111 PMID:29990575 PMID:33359023 More... RGD:15090820 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983
JBrowse link
G Tnfrsf11b tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin) multiple interactions
increases expression
EXP fulvestrant inhibits the reaction [dioscin results in increased expression of TNFRSF11B mRNA]; LRP5 protein affects the reaction [dioscin results in increased expression of TNFRSF11B mRNA] CTD PMID:24742230 NCBI chr15:54,114,014...54,141,700
Ensembl chr15:54,114,015...54,141,880
JBrowse link
G Tnfrsf1a tumor necrosis factor receptor superfamily, member 1a increases expression ISO dioscin results in increased expression of TNFRSF1A mRNA; dioscin results in increased expression of TNFRSF1A protein CTD PMID:22334414 PMID:29990575 PMID:33359023 NCBI chr 6:125,326,686...125,339,446
Ensembl chr 6:125,326,325...125,339,447
JBrowse link
G Tnfrsf25 tumor necrosis factor receptor superfamily, member 25 increases expression ISO dioscin results in increased expression of TNFRSF25 mRNA CTD PMID:29990575 PMID:33359023 NCBI chr 4:152,199,985...152,204,568
Ensembl chr 4:152,200,391...152,204,576
JBrowse link
G Tnfsf11 tumor necrosis factor (ligand) superfamily, member 11 decreases expression
multiple interactions
EXP dioscin results in decreased expression of TNFSF11 mRNA
fulvestrant inhibits the reaction [dioscin results in increased expression of TNFSF11 mRNA]; LRP5 protein affects the reaction [dioscin results in increased expression of TNFSF11 mRNA]
CTD PMID:24742230 NCBI chr14:78,514,886...78,545,483
Ensembl chr14:78,514,885...78,545,483
JBrowse link
G Tradd TNFRSF1A-associated via death domain increases expression ISO dioscin results in increased expression of TRADD mRNA CTD PMID:29990575 PMID:33359023 NCBI chr 8:105,985,207...105,991,226
Ensembl chr 8:105,984,918...105,991,241
JBrowse link
G Traf1 TNF receptor-associated factor 1 increases expression ISO dioscin results in increased expression of TRAF1 protein CTD PMID:22334414 NCBI chr 2:34,831,762...34,851,784
Ensembl chr 2:34,831,762...34,851,784
JBrowse link
G Trp53 transformation related protein 53 multiple interactions
increases expression
EXP
ISO
dioscin inhibits the reaction [Acetaminophen results in increased expression of TRP53 protein]; dioscin inhibits the reaction [Ethanol results in increased expression of TRP53 protein]
dioscin results in increased expression of TP53 mRNA; dioscin results in increased expression of TP53 protein
CTD PMID:22334414 PMID:22939915 PMID:24146112 PMID:29990575 NCBI chr11:69,471,174...69,482,699
Ensembl chr11:69,471,185...69,482,699
JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions ISO dioscin inhibits the reaction [VEGFA protein results in increased phosphorylation of AKT1 protein]; dioscin inhibits the reaction [VEGFA protein results in increased phosphorylation of KDR protein]; dioscin inhibits the reaction [VEGFA protein results in increased phosphorylation of MAPK1 protein]; dioscin inhibits the reaction [VEGFA protein results in increased phosphorylation of MAPK3 protein]; dioscin inhibits the reaction [VEGFA protein results in increased phosphorylation of PTK2 protein]; dioscin inhibits the reaction [VEGFA protein results in increased phosphorylation of SRC protein] CTD PMID:25111127 NCBI chr17:46,327,919...46,343,303
Ensembl chr17:46,327,919...46,343,295
JBrowse link
G Wee1 WEE 1 homolog 1 (S. pombe) increases expression ISO dioscin results in increased expression of WEE1 mRNA CTD PMID:29990575 NCBI chr 7:109,721,266...109,742,506
Ensembl chr 7:109,721,253...109,742,493
JBrowse link
eritoran term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp7b ATPase, copper transporting, beta polypeptide multiple interactions EXP eritoran inhibits the reaction [ATP7B mutant form results in increased expression of IL1B protein]; eritoran inhibits the reaction [ATP7B mutant form results in increased expression of IL6 protein]; eritoran inhibits the reaction [ATP7B mutant form results in increased expression of MYD88 protein]; eritoran inhibits the reaction [ATP7B mutant form results in increased expression of PTGS2 protein]; eritoran inhibits the reaction [ATP7B mutant form results in increased expression of RELA protein]; eritoran inhibits the reaction [ATP7B mutant form results in increased expression of TLR4 protein]; eritoran inhibits the reaction [ATP7B mutant form results in increased expression of TNF protein] CTD PMID:38761876 NCBI chr 8:22,482,799...22,550,347
Ensembl chr 8:22,482,801...22,550,321
JBrowse link
G Bax BCL2-associated X protein multiple interactions EXP eritoran inhibits the reaction [NLRP3 mutant form results in increased expression of BAX protein] CTD PMID:38761876 NCBI chr 7:45,111,124...45,116,332
Ensembl chr 7:45,111,121...45,116,322
JBrowse link
G Bcl2 B cell leukemia/lymphoma 2 multiple interactions EXP eritoran inhibits the reaction [NLRP3 mutant form results in decreased expression of BCL2 protein] CTD PMID:38761876 NCBI chr 1:106,465,906...106,642,020
Ensembl chr 1:106,465,908...106,642,004
JBrowse link
G Casp1 caspase 1 multiple interactions EXP eritoran inhibits the reaction [NLRP3 mutant form results in increased cleavage of CASP1 protein] CTD PMID:38761876 NCBI chr 9:5,298,517...5,307,281
Ensembl chr 9:5,298,508...5,307,290
JBrowse link
G Casp3 caspase 3 multiple interactions EXP eritoran inhibits the reaction [NLRP3 mutant form results in increased cleavage of CASP3 protein] CTD PMID:38761876 NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724
JBrowse link
G Casp8 caspase 8 multiple interactions EXP eritoran inhibits the reaction [NLRP3 mutant form results in increased cleavage of CASP8 protein] CTD PMID:38761876 NCBI chr 1:58,834,553...58,886,663
Ensembl chr 1:58,834,533...58,886,662
JBrowse link
G Gpt glutamic pyruvic transaminase, soluble multiple interactions EXP eritoran inhibits the reaction [Azathioprine results in increased expression of GPT protein]; eritoran inhibits the reaction [Diclofenac results in increased expression of GPT protein]; eritoran inhibits the reaction [Dicloxacillin results in increased expression of GPT protein]; eritoran inhibits the reaction [Halothane results in increased expression of GPT protein] CTD PMID:24184165 PMID:24747151 NCBI chr15:76,580,926...76,583,875
Ensembl chr15:76,579,916...76,583,886
JBrowse link
G Gsdmd gasdermin D multiple interactions EXP eritoran inhibits the reaction [NLRP3 mutant form results in increased cleavage of GSDMD protein] CTD PMID:38761876 NCBI chr15:75,733,990...75,739,257
Ensembl chr15:75,734,176...75,739,257
JBrowse link
G Il1b interleukin 1 beta multiple interactions EXP eritoran inhibits the reaction [ATP7B mutant form results in increased expression of IL1B protein] CTD PMID:38761876 NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059
JBrowse link
G Il6 interleukin 6 multiple interactions EXP eritoran inhibits the reaction [ATP7B mutant form results in increased expression of IL6 protein] CTD PMID:38761876 NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979
JBrowse link
G Mlkl mixed lineage kinase domain-like multiple interactions EXP eritoran inhibits the reaction [NLRP3 mutant form results in increased expression of and results in increased phosphorylation of MLKL protein] CTD PMID:38761876 NCBI chr 8:112,037,879...112,065,081
Ensembl chr 8:112,038,429...112,064,809
JBrowse link
G Myd88 myeloid differentiation primary response gene 88 multiple interactions EXP eritoran inhibits the reaction [ATP7B mutant form results in increased expression of MYD88 protein] CTD PMID:38761876 NCBI chr 9:119,165,000...119,169,084
Ensembl chr 9:119,165,000...119,170,477
JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 multiple interactions EXP eritoran inhibits the reaction [NLRP3 mutant form results in decreased expression of BCL2 protein]; eritoran inhibits the reaction [NLRP3 mutant form results in increased cleavage of CASP1 protein]; eritoran inhibits the reaction [NLRP3 mutant form results in increased cleavage of CASP3 protein]; eritoran inhibits the reaction [NLRP3 mutant form results in increased cleavage of CASP8 protein]; eritoran inhibits the reaction [NLRP3 mutant form results in increased cleavage of GSDMD protein]; eritoran inhibits the reaction [NLRP3 mutant form results in increased expression of and results in increased phosphorylation of MLKL protein]; eritoran inhibits the reaction [NLRP3 mutant form results in increased expression of and results in increased phosphorylation of RIPK3 protein]; eritoran inhibits the reaction [NLRP3 mutant form results in increased expression of BAX protein]; eritoran inhibits the reaction [NLRP3 mutant form results in increased expression of TLR4 protein] CTD PMID:38761876 NCBI chr11:59,432,395...59,457,781
Ensembl chr11:59,432,394...59,457,782
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions EXP eritoran inhibits the reaction [ATP7B mutant form results in increased expression of PTGS2 protein] CTD PMID:38761876 NCBI chr 1:149,975,851...149,983,978
Ensembl chr 1:149,975,782...149,983,978
JBrowse link
G Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) multiple interactions EXP eritoran inhibits the reaction [ATP7B mutant form results in increased expression of RELA protein] CTD PMID:38761876 NCBI chr19:5,686,993...5,698,162
Ensembl chr19:5,687,511...5,698,158
JBrowse link
G Ripk3 receptor-interacting serine-threonine kinase 3 multiple interactions EXP eritoran inhibits the reaction [NLRP3 mutant form results in increased expression of and results in increased phosphorylation of RIPK3 protein] CTD PMID:38761876 NCBI chr14:56,022,452...56,026,314
Ensembl chr14:56,022,452...56,026,322
JBrowse link
G Tlr4 toll-like receptor 4 multiple interactions EXP eritoran inhibits the reaction [ATP7B mutant form results in increased expression of TLR4 protein]; eritoran inhibits the reaction [NLRP3 mutant form results in increased expression of TLR4 protein] CTD PMID:38761876 NCBI chr 4:66,745,788...66,765,338
Ensembl chr 4:66,745,821...66,848,521
JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP eritoran inhibits the reaction [ATP7B mutant form results in increased expression of TNF protein] CTD PMID:38761876 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983
JBrowse link
fondaparinux term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G F10 coagulation factor X decreases activity ISO fondaparinux results in decreased activity of F10 protein CTD PMID:16084352 NCBI chr 8:13,087,308...13,106,676
Ensembl chr 8:13,087,308...13,106,676
JBrowse link
lipid As term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccl3 C-C motif chemokine ligand 3 increases expression
multiple interactions
EXP Lipid A results in increased expression of CCL3 mRNA
anacetrapib inhibits the reaction [Lipid A results in increased expression of CCL3 mRNA]
CTD PMID:20448206 NCBI chr11:83,538,669...83,540,204
Ensembl chr11:83,538,670...83,540,181
JBrowse link
G Cxcl15 C-X-C motif chemokine ligand 15 multiple interactions
increases expression
ISO [Acetylmuramyl-Alanyl-Isoglutamine co-treated with Lipid A] results in increased expression of CXCL8 protein; [heptanoyl-gamma-D-glutamyl-L-meso-diaminopimelyl-D-alanine co-treated with Lipid A] results in increased expression of CXCL8 protein
Lipid A results in increased expression of CXCL8 protein
CTD PMID:16299289 NCBI chr 5:90,942,393...90,950,926
Ensembl chr 5:90,942,393...90,950,926
JBrowse link
G Ifng interferon gamma multiple interactions
increases expression
ISO [Acetylmuramyl-Alanyl-Isoglutamine co-treated with Lipid A] results in increased expression of IFNG mRNA; [Acetylmuramyl-Alanyl-Isoglutamine co-treated with Lipid A] results in increased expression of IFNG protein; [heptanoyl-gamma-D-glutamyl-L-meso-diaminopimelyl-D-alanine co-treated with Lipid A] results in increased expression of IFNG mRNA; [heptanoyl-gamma-D-glutamyl-L-meso-diaminopimelyl-D-alanine co-treated with Lipid A] results in increased expression of IFNG protein
Lipid A results in increased expression of IFNG mRNA; Lipid A results in increased expression of IFNG protein
CTD PMID:16299289 NCBI chr10:118,276,951...118,281,799
Ensembl chr10:118,276,951...118,281,797
JBrowse link
G Il12a interleukin 12a multiple interactions
increases expression
ISO [Acetylmuramyl-Alanyl-Isoglutamine co-treated with Lipid A] results in increased expression of [IL12A protein binds to IL12B protein]; [Acetylmuramyl-Alanyl-Isoglutamine co-treated with Lipid A] results in increased expression of IL12A mRNA; [heptanoyl-gamma-D-glutamyl-L-meso-diaminopimelyl-D-alanine co-treated with Lipid A] results in increased expression of [IL12A protein binds to IL12B protein]; [heptanoyl-gamma-D-glutamyl-L-meso-diaminopimelyl-D-alanine co-treated with Lipid A] results in increased expression of IL12A mRNA; Lipid A results in increased expression of [IL12A protein binds to IL12B protein]
Lipid A results in increased expression of IL12A mRNA
CTD PMID:16299289 NCBI chr 3:68,597,977...68,605,881
Ensembl chr 3:68,597,977...68,605,880
JBrowse link
G Il12b interleukin 12b multiple interactions
increases expression
ISO [Acetylmuramyl-Alanyl-Isoglutamine co-treated with Lipid A] results in increased expression of [IL12A protein binds to IL12B protein]; [Acetylmuramyl-Alanyl-Isoglutamine co-treated with Lipid A] results in increased expression of IL12B mRNA; [heptanoyl-gamma-D-glutamyl-L-meso-diaminopimelyl-D-alanine co-treated with Lipid A] results in increased expression of [IL12A protein binds to IL12B protein]; [heptanoyl-gamma-D-glutamyl-L-meso-diaminopimelyl-D-alanine co-treated with Lipid A] results in increased expression of IL12B mRNA; Lipid A results in increased expression of [IL12A protein binds to IL12B protein]
Lipid A results in increased expression of IL12B mRNA
CTD PMID:16299289 NCBI chr11:44,290,890...44,305,504
Ensembl chr11:44,290,890...44,304,860
JBrowse link
G Il15 interleukin 15 multiple interactions
increases expression
ISO [Acetylmuramyl-Alanyl-Isoglutamine co-treated with Lipid A] results in increased expression of IL15 mRNA; [heptanoyl-gamma-D-glutamyl-L-meso-diaminopimelyl-D-alanine co-treated with Lipid A] results in increased expression of IL15 mRNA
Lipid A results in increased expression of IL15 mRNA
CTD PMID:16299289 NCBI chr 8:83,058,253...83,129,883
Ensembl chr 8:83,058,261...83,129,851
JBrowse link
G Il18 interleukin 18 increases expression ISO Lipid A results in increased expression of IL18 mRNA CTD PMID:16299289 NCBI chr 9:50,466,000...50,493,141
Ensembl chr 9:50,466,127...50,493,140
JBrowse link
G Il6 interleukin 6 multiple interactions
increases expression
EXP anacetrapib inhibits the reaction [Lipid A results in increased expression of IL6 mRNA] CTD PMID:20448206 NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979
JBrowse link
G Tnf tumor necrosis factor multiple interactions
increases expression
EXP anacetrapib inhibits the reaction [Lipid A results in increased expression of TNF mRNA] CTD PMID:20448206 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983
JBrowse link
madecassoside term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bax BCL2-associated X protein multiple interactions EXP
ISO
madecassoside inhibits the reaction [Cisplatin results in increased expression of BAX mRNA]; madecassoside inhibits the reaction [Cisplatin results in increased expression of BAX protein] CTD PMID:37087747 NCBI chr 7:45,111,124...45,116,332
Ensembl chr 7:45,111,121...45,116,322
JBrowse link
G Bcl2 B cell leukemia/lymphoma 2 multiple interactions ISO madecassoside inhibits the reaction [Cisplatin results in decreased expression of BCL2 mRNA] CTD PMID:37087747 NCBI chr 1:106,465,906...106,642,020
Ensembl chr 1:106,465,908...106,642,004
JBrowse link
G Casp3 caspase 3 multiple interactions EXP madecassoside inhibits the reaction [Cisplatin results in increased expression of and results in increased cleavage of CASP3 protein] CTD PMID:37087747 NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724
JBrowse link
G Cyp2c38 cytochrome P450, family 2, subfamily c, polypeptide 38 decreases activity ISO madecassoside results in decreased activity of CYP2C19 protein CTD PMID:21349323 NCBI chr19:39,379,109...39,451,519
Ensembl chr19:39,378,000...39,451,519
JBrowse link
G Havcr1 hepatitis A virus cellular receptor 1 multiple interactions EXP madecassoside inhibits the reaction [Cisplatin results in increased expression of HAVCR1 mRNA] CTD PMID:37087747 NCBI chr11:46,630,644...46,670,405
Ensembl chr11:46,625,907...46,670,405
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO madecassoside inhibits the reaction [Cisplatin results in increased expression of IL1B mRNA] CTD PMID:37087747 NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059
JBrowse link
G Il6 interleukin 6 multiple interactions ISO madecassoside inhibits the reaction [Cisplatin results in increased expression of IL6 mRNA] CTD PMID:37087747 NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979
JBrowse link
G Lcn2 lipocalin 2 multiple interactions EXP madecassoside inhibits the reaction [Cisplatin results in increased expression of LCN2 mRNA]; madecassoside inhibits the reaction [Cisplatin results in increased expression of LCN2 protein] CTD PMID:37087747 NCBI chr 2:32,274,649...32,277,751
Ensembl chr 2:32,274,645...32,278,264
JBrowse link
G Mapk1 mitogen-activated protein kinase 1 multiple interactions EXP madecassoside inhibits the reaction [Cisplatin results in increased phosphorylation of MAPK1 protein] CTD PMID:37087747 NCBI chr16:16,801,246...16,865,317
Ensembl chr16:16,801,246...16,865,317
JBrowse link
G Mapk14 mitogen-activated protein kinase 14 multiple interactions EXP madecassoside inhibits the reaction [Cisplatin results in increased phosphorylation of MAPK14 protein] CTD PMID:37087747 NCBI chr17:28,910,316...28,967,379
Ensembl chr17:28,910,303...28,967,380
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO madecassoside inhibits the reaction [Cisplatin results in increased expression of TNF mRNA] CTD PMID:37087747 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983
JBrowse link
soyasaponin I term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il1b interleukin 1 beta multiple interactions EXP soyasaponin I inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B protein]; soyasaponin I inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein] CTD PMID:20923188 NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059
JBrowse link
G Il6 interleukin 6 multiple interactions EXP soyasaponin I inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 protein] CTD PMID:20923188 NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979
JBrowse link
G Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha multiple interactions EXP soyasaponin I inhibits the reaction [Lipopolysaccharides results in increased degradation of and results in increased phosphorylation of NFKBIA protein] CTD PMID:20923188 NCBI chr12:55,536,194...55,539,432
Ensembl chr12:55,536,195...55,539,432
JBrowse link
G Nos2 nitric oxide synthase 2, inducible multiple interactions EXP soyasaponin I inhibits the reaction [Lipopolysaccharides results in increased activity of NOS2 protein]; soyasaponin I inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; soyasaponin I inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]; soyasaponin I inhibits the reaction [Lipopolysaccharides results in increased secretion of NOS2 protein]; soyasaponin I inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of NOS2 protein] CTD PMID:20923188 PMID:21397503 NCBI chr11:78,811,613...78,851,052
Ensembl chr11:78,811,613...78,851,080
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions EXP soyasaponin I inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein]; soyasaponin I inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 protein] CTD PMID:20923188 NCBI chr 1:149,975,851...149,983,978
Ensembl chr 1:149,975,782...149,983,978
JBrowse link
G Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) multiple interactions EXP soyasaponin I inhibits the reaction [Lipopolysaccharides affects the localization of RELA protein] CTD PMID:20923188 NCBI chr19:5,686,993...5,698,162
Ensembl chr19:5,687,511...5,698,158
JBrowse link
G Ren1 renin 1 structural decreases activity ISO soyasaponin I results in decreased activity of REN protein CTD PMID:19060406 PMID:20460744 NCBI chr 1:133,278,412...133,288,058
Ensembl chr 1:133,278,248...133,288,063
JBrowse link
G St3gal4 ST3 beta-galactoside alpha-2,3-sialyltransferase 4 decreases expression ISO soyasaponin I results in decreased expression of ST3GAL4 mRNA CTD PMID:15661230 NCBI chr 9:34,957,872...35,028,160
Ensembl chr 9:34,957,872...35,030,564
JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP soyasaponin I inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]; soyasaponin I inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein] CTD PMID:20923188 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983
JBrowse link
sucrose octasulfate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fgfr2 fibroblast growth factor receptor 2 affects binding ISO sucrose octasulfate binds to FGFR2 protein CTD PMID:15047176 NCBI chr 7:129,764,181...129,868,538
Ensembl chr 7:129,764,181...132,725,079
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 22327
    chemical entity 22326
      atom 22322
        nonmetal atom 22154
          oxygen atom 21529
            oxygen molecular entity 21529
              organooxygen compound 20949
                carbohydrates and carbohydrate derivatives 16077
                  glycan 8924
                    oligosaccharide derivative 162
                      2,2'-dithiobis\ 0
                      2,2'-dithiobis\ 0
                      6,6'-dithiobis\ 0
                      6,6'-dithiodi[1-(2-acetamido-4-amino-2,4-dideoxy-alpha-D-fucosyloxy)hexane] 0
                      6,6'-dithiodi[1-(alpha-D-galacturonosyloxy)hexane] 0
                      6,6'-dithiodi\ 0
                      D-GalNAc-(1->3)-D-GalNAc-(1->3)-[D-GalNAc-(1->2)-L-Fuc-(1->4)]-D-GlcNAc-(1->3)-[L-Fuc-(1->6)]-D-GalNAc-ol 0
                      D-GalNAc-(1->4)-D-GlcNAc-(1->3)-[D-GalNAc-(1->4)-D-GlcNAc-(1->6)]-D-GalNAc-ol 0
                      D-GalNAc-(1->4)-D-GlcNAc-(1->6)-[D-GalNAc-(1->4)-[L-Fuc-(1->3)]-D-GlcNAc-(1->3)]-D-GalNAc-ol 0
                      D-GalNAc-(1->4)-[L-Fuc-(1->3)]D-GlcNAc-(1->3)-[D-GalNAc-(1->4)-[L-Fuc-(1->3)]-D-GlcNAc-(1->6)]-D-GalNAc-ol 0
                      S. pneumoniae serotype 14 capsular oligosaccharide derivative 0
                      [8)-alpha-Neu5Pr-(2->]10 0
                      [beta-D-Galf-(1->5)-beta-D-Galf-(1->6)]14-beta-D-Galf-(1->5)-beta-D-Galf-(1->4)-alpha-L-Rhap-(1->3)-alpha-D-GlcpNAc-1-diphospho-trans,octacis-decaprenol 0
                      alpha-D-Ara-(1->5)-[alpha-D-Ara-(1->5)-alpha-D-Ara-(1->3)]-alpha-D-Ara-(1->5)-alpha-D-Ara-(1->5)-alpha-D-Ara-(1->2)-[alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)-[alpha-D-Man-(1->2)]-alpha-D-Man-(1->6)-alpha-D-Man-(1->6)-alpha-D-ManO[CH2]6N3 0
                      alpha-D-Gal-(1->3)-beta-D-GlcNAc-(1->4)-alpha-D-GlcN6PEtn-(1->4)-[alpha-LD-Hep-(1->2)-alpha-DD-Hep-(1->2)]-alpha-D-GalA-(1->3)-[alpha-LD-Hep-(1->7)]-alpha-LD-Hep6PEtn-(1->3)-[beta-D-Glc-(1->4)]-alpha-LD-Hep-(1->5)-[alpha-Kdo-(2->4)][beta-L-Arap4N-(1->8)]-alpha-Kdo 0
                      alpha-D-GalN-(1->4)-[alpha-DD-Hep-(1->2)]-alpha-D-GalA-(1->3)-[alpha-LD-Hep-(1->7)]-alpha-LD-Hep6PEtn-(1->3)-[beta-D-Glc-(1->4)]-alpha-LD-Hep-(1->5)-[alpha-Kdo-(2->4)][beta-L-Arap4N-(1->8)]-alpha-Kdo 0
                      alpha-D-GalN-(1->4)-[alpha-LD-Hep-(1->2)-alpha-DD-Hep-(1->2)]-alpha-D-GalA-(1->3)-[alpha-LD-Hep-(1->7)]-alpha-LD-Hep6PEtn-(1->3)-[beta-D-Glc-(1->4)]-alpha-LD-Hep-(1->5)-[alpha-Kdo-(2->4)][beta-L-Arap4N-(1->8)]-alpha-Kdo 0
                      alpha-D-GalNAc-(1->2)-alpha-DD-Hep-(1->6)-alpha-D-GlcNGly-(1->4)-[alpha-LD-Hep-(1->2)-alpha-DD-Hep-(1->2)]-alpha-D-GalA-(1->3)-[alpha-LD-Hep-(1->7)]-alpha-LD-Hep6PEtn-(1->3)-[beta-D-Glc-(1->4)]-alpha-LD-Hep-(1->5)-[alpha-Kdo-(2->4)][beta-L-Arap4N-(1->8)]-alpha-Kdo 0
                      alpha-D-Galp-(1->2)-[alpha-Abep-(1->3)]-alpha-D-Manp-(1->4)-alpha-L-Rhap-(1->3)-alpha-D-Galp-(1->2)-[alpha-Abep-(1->3)]-alpha-D-Manp-(1->4)-alpha-L-Rhap-(1->3)-alpha-D-Galp-(1->2)-[alpha-Abep-(1->3)]-alpha-D-Manp-(1->4)-alpha-L-RhapOMe 0
                      alpha-D-Glc-(1->4)-alpha-D-GalNAc-(1->2)-alpha-DD-Hep-(1->6)-alpha-D-GlcN-(1->4)-[alpha-LD-Hep-(1->2)-alpha-DD-Hep-(1->2)]-alpha-D-GalA-(1->3)-[alpha-LD-Hep-(1->7)]-alpha-LD-Hep6PEtn-(1->3)-[beta-D-Glc-(1->4)]-alpha-LD-Hep-(1->5)-[alpha-Kdo-(2->4)][beta-L-Arap4N-(1->8)]-alpha-Kdo 0
                      alpha-D-Glc-(1->4)-alpha-D-GalNAc-(1->2)-alpha-DD-Hep-(1->6)-alpha-D-GlcNGly-(1->4)-[alpha-LD-Hep-(1->2)-alpha-DD-Hep-(1->2)]-alpha-D-GalA-(1->3)-[alpha-LD-Hep-(1->7)]-alpha-LD-Hep6PEtn-(1->3)-[beta-D-Glc-(1->4)]-alpha-LD-Hep-(1->5)-[alpha-Kdo-(2->4)][beta-L-Arap4N-(1->8)]-alpha-Kdo 0
                      alpha-D-Glc-(1->6)-beta-D-Gal-(1->4)-(1S)-D-GaloNAc-(1->4,6)-alpha-D-GalN-(1->4)-[alpha-LD-Hep-(1->2)-alpha-DD-Hep-(1->2)]-alpha-D-GalA-(1->3)-[alpha-LD-Hep-(1->7)]-alpha-LD-Hep6PEtn-(1->3)-[beta-D-Glc-(1->4)]-alpha-LD-Hep-(1->5)-[alpha-Kdo-(2->4)][beta-L-Arap4N-(1->8)]-alpha-Kdo 0
                      alpha-D-GlcNAc-(1->2)-alpha-D-Glc-(1->2)-alpha-D-Gal-(1->3)-[alpha-D-Gal-(1->6)]-alpha-D-Glc-(1->3)-[L-glycero-alpha-D-manno-Hep-(1->7)]-L-glycero-alpha-D-manno-Hep-(1->3)-L-glycero-D-manno-Hep 0
                      alpha-D-GlcNAc-(1->2)-alpha-D-Glc-(1->3)-[alpha-D-Gal-(1->6)]-D-Glc-(1->3)-[LD-Hep-(1->7)]-alpha-LD-Hep4P-(1->3)-alpha-LD-Hep4PPEtN-(1->5)-alpha-D-Kdo 0
                      alpha-D-Glcp6S-(1->4)-beta-D-Glcp6SOMe 0
                      alpha-D-GlcpNAc-(1->4)-beta-D-Manp2NAc3NAcA-(1->3)-beta-L-FucpNAc4NMe-(1->6)-[L-alpha-D-Hepp-(1->4)]-alpha-D-GlcpN-(1->4)-[alpha-D-GalpNA-(1->6)]-beta-D-Glcp-(1->4)-\{alpha-D-GlcpN-(1->7)-[alpha-D-GlcpA-(1->2)]-D-alpha-D-Hepp-(1->3)\}-L-alpha-D-Hepp-(1->5)-alpha-Kdop 0
                      alpha-Delta(4,5)HexpUA-(1->3)-beta-D-GalpNAc6S-(1->4)-beta-D-GlcpUA-(1->3)-beta-D-GalpNAc6S-(1->4)-beta-D-GlcpUA-(1->3)-beta-D-GalpNAc4S-(1->4)-beta-D-GlcpUA2S-(1->3)-D-GalpNAc6S 0
                      alpha-Delta(4,5)HexpUA2S-(1->3)-beta-D-GalpNAc6S-(1->4)-beta-D-GlcpUA-(1->3)-beta-D-GalpNAc6S-(1->4)-beta-D-GlcpUA-(1->3)-beta-D-GalpNAc6S-(1->4)-beta-D-GlcpUA-(1->3)-D-GalpNAc6S 0
                      alpha-L-Fuc-(1->2)-beta-D-Gal-(1->4)-[alpha-L-Fuc-(1->3)]-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->3)-alpha-DD-Hep-(1->3)-alpha-DD-Hep-(1->3)-alpha-DD-Hep-(1->3)-alpha-DD-Hep-(1->3)-alpha-DD-Hep-(1->6)-alpha-DD-Hep-(1->2)-alpha-DD-Hep-(1->2)-alpha-DD-Hep-O[CH2]3NH2 + 0
                      alpha-L-Fuc3NHb-(1->4)-alpha-D-Gal-(1->6)-beta-D-Glc-(1->3)-alpha-D-GalN6PEtn-(1->4)-[alpha-LD-Hep-(1->2)-alpha-DD-Hep-(1->2)]-alpha-D-GalA-(1->3)-[alpha-LD-Hep-(1->7)]-alpha-LD-Hep6PEtn-(1->3)-[beta-D-Glc-(1->4)]-alpha-LD-Hep-(1->5)-[alpha-Kdo-(2->4)][beta-L-Arap4N-(1->8)]-alpha-Kdo 0
                      alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->3)-beta-Gal-(1->3)-beta-GalNAc-(1->4)-[alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->3)]-beta-Gal-(1->4)-beta-Glc 0
                      amino oligosaccharide + 2
                      avilamycin A 0
                      avilamycin A precursor 0
                      beta-D-Gal-(1->4)-(1S)-D-GaloNAc-(1->4,6)-alpha-D-GalN-(1->4)-[alpha-LD-Hep-(1->2)-alpha-DD-Hep-(1->2)]-alpha-D-GalA-(1->3)-[alpha-LD-Hep-(1->7)]-alpha-LD-Hep6PEtn-(1->3)-[beta-D-Glc-(1->4)]-alpha-LD-Hep-(1->5)-[alpha-Kdo-(2->4)][beta-L-Arap4N-(1->8)]-alpha-Kdo 0
                      beta-D-GalALys4PEtn-(1->3)-beta-D-GlcNAc-(1->6)-alpha-D-GlcNGly-(1->4)-[alpha-LD-Hep-(1->2)-alpha-DD-Hep-(1->2)]-alpha-D-GalA-(1->3)-[alpha-LD-Hep-(1->7)]-alpha-LD-Hep6PEtn-(1->3)-[beta-D-Glc-(1->4)]-alpha-LD-Hep-(1->5)-[alpha-Kdo-(2->4)][beta-L-Arap4N-(1->8)]-alpha-Kdo 0
                      beta-D-Glc-(1->3)-alpha-D-GalN-(1->4)-[alpha-LD-Hep-(1->2)-alpha-DD-Hep-(1->2)]-alpha-D-GalA-(1->3)-[alpha-LD-Hep-(1->7)]-alpha-LD-Hep6PEtn-(1->3)-[beta-D-Glc-(1->4)]-alpha-LD-Hep-(1->5)-[alpha-Kdo-(2->4)][beta-L-Arap4N-(1->8)]-alpha-Kdo 0
                      beta-D-Glc-(1->3)-beta-D-Glc-(1->3)-beta-D-Glc-(1->3)-beta-D-Glc-(1->3)-[beta-D-Glc-(1->3)-beta-D-Glc-(1->3)-beta-D-Glc-(1->3)-beta-D-Glc-(1->6)]-beta-D-Glc-(1->3)-beta-D-Glc-(1->3)-beta-D-Glc-(1->3)-beta-D-Glc-(1->3)-beta-D-Glc-O[CH2]2NH2 0
                      beta-D-Glc-(1->3)-beta-D-Glc-(1->3)-beta-D-Glc-(1->3)-beta-D-Glc-(1->3)-[beta-D-Glc-(1->3)-beta-D-Glc-(1->6)]-beta-D-Glc-(1->3)-beta-D-Glc-(1->3)-beta-D-Glc-(1->3)-beta-D-Glc-(1->3)-beta-D-Glc-O[CH2]2NH2 0
                      beta-D-Glc-(1->3)-beta-D-Glc-(1->3)-beta-D-Glc-(1->3)-beta-D-Glc-(1->3)-[beta-D-Glc-(1->6)-beta-D-Glc-(1->6)-beta-D-Glc-(1->6)-beta-D-Glc-(1->6)-beta-D-Glc-(1->6)]-beta-D-Glc-(1->3)-beta-D-Glc-(1->3)-beta-D-Glc-(1->3)-beta-D-Glc-(1->3)-beta-D-Glc-O[CH2]2NH2 0
                      beta-D-Glc-(1->4)-alpha-D-GlcNAc-(1->4)-alpha-D-GalN6Ac(1->4)-[alpha-LD-Hep-(1->2)-alpha-DD-Hep-(1->2)]-alpha-D-GalA-(1->3)-[alpha-LD-Hep-(1->7)]-alpha-LD-Hep6PEtn-(1->3)-[beta-D-Glc-(1->4)]-alpha-LD-Hep-(1->5)-[alpha-Kdo-(2->4)][beta-L-Arap4N-(1->8)]-alpha-Kdo 0
                      beta-D-GlcNAc-(1->3)-alpha-D-GlcN-(1->4)-[alpha-LD-Hep-(1->2)-alpha-DD-Hep-(1->2)]-alpha-D-GalA-(1->3)-[beta-D-GalAN-(1->7)-alpha-LD-Hep-(1->7)]-alpha-LD-Hep6PEtn-(1->3)-[beta-D-Glc-(1->4)]-alpha-LD-Hep-(1->5)-[alpha-Kdo-(2->4)][beta-L-Arap4N-(1->8)]-alpha-Kdo 0
                      beta-D-GlcpNAc-(1->2)-alpha-D-Manp-(1->3)-[beta-D-GlcpNAc-(1->2)-alpha-D-Manp-(1->6)]-[beta-D-Xylp-(1->2)]-beta-D-Manp-(1->4)-beta-D-GlcpNAc-(1->4)-D-GlcpNAc + 0
                      beta-D-GlcpNAc-(1->2)-alpha-D-Manp-(1->3)-[beta-D-GlcpNAc-(1->2)-alpha-D-Manp-(1->6)]-[beta-D-Xylp-(1->2)]-beta-D-Manp-(1->4)-beta-D-GlcpNAc-(1->4)-[alpha-L-Fucp-(1->3)]-D-GlcpNAc + 0
                      beta-D-GlcpNAc-(1->3)-beta-D-Galp-(1->4)-beta-D-Glcp-(1->2)-alpha-D-Manp-(1->3)-[beta-D-GlcpNAc-(1->3)-beta-D-Galp-(1->4)-beta-D-Glcp-(1->2)-alpha-D-Manp-(1->6)]-beta-D-Manp-(1->4)-beta-D-GlcpNAc-(1->4)-beta-D-GlcpNAc 0
                      decasaccharide derivative + 0
                      dolichol-linked oligosaccharide 0
                      heparan sulfate oligosaccharide + 0
                      heparin oligosaccharide + 1
                      heptasaccharide derivative + 0
                      hexasaccharide derivative + 0
                      lipooligosaccharide + 25
                      mannooligosaccharide derivative + 0
                      nonasaccharide derivative + 0
                      octasaccharide derivative + 0
                      oligosaccharide phosphate + 0
                      oligosaccharide sulfate + 2
                      pentasaccharide derivative + 17
                      tetrasaccharide derivative + 15
                      trisaccharide derivative + 124
Path 2
Term Annotations click to browse term
  CHEBI ontology 22327
    subatomic particle 22322
      composite particle 22322
        hadron 22322
          baryon 22322
            nucleon 22322
              atomic nucleus 22322
                atom 22322
                  main group element atom 22204
                    p-block element atom 22204
                      carbon group element atom 22007
                        carbon atom 21947
                          organic molecular entity 21947
                            heteroorganic entity 21597
                              organochalcogen compound 21092
                                organooxygen compound 20949
                                  carbohydrates and carbohydrate derivatives 16077
                                    carbohydrate 16077
                                      oligosaccharide 629
                                        oligosaccharide derivative 162
                                          2,2'-dithiobis\ 0
                                          2,2'-dithiobis\ 0
                                          6,6'-dithiobis\ 0
                                          6,6'-dithiodi[1-(2-acetamido-4-amino-2,4-dideoxy-alpha-D-fucosyloxy)hexane] 0
                                          6,6'-dithiodi[1-(alpha-D-galacturonosyloxy)hexane] 0
                                          6,6'-dithiodi\ 0
                                          D-GalNAc-(1->3)-D-GalNAc-(1->3)-[D-GalNAc-(1->2)-L-Fuc-(1->4)]-D-GlcNAc-(1->3)-[L-Fuc-(1->6)]-D-GalNAc-ol 0
                                          D-GalNAc-(1->4)-D-GlcNAc-(1->3)-[D-GalNAc-(1->4)-D-GlcNAc-(1->6)]-D-GalNAc-ol 0
                                          D-GalNAc-(1->4)-D-GlcNAc-(1->6)-[D-GalNAc-(1->4)-[L-Fuc-(1->3)]-D-GlcNAc-(1->3)]-D-GalNAc-ol 0
                                          D-GalNAc-(1->4)-[L-Fuc-(1->3)]D-GlcNAc-(1->3)-[D-GalNAc-(1->4)-[L-Fuc-(1->3)]-D-GlcNAc-(1->6)]-D-GalNAc-ol 0
                                          S. pneumoniae serotype 14 capsular oligosaccharide derivative 0
                                          [8)-alpha-Neu5Pr-(2->]10 0
                                          [beta-D-Galf-(1->5)-beta-D-Galf-(1->6)]14-beta-D-Galf-(1->5)-beta-D-Galf-(1->4)-alpha-L-Rhap-(1->3)-alpha-D-GlcpNAc-1-diphospho-trans,octacis-decaprenol 0
                                          alpha-D-Ara-(1->5)-[alpha-D-Ara-(1->5)-alpha-D-Ara-(1->3)]-alpha-D-Ara-(1->5)-alpha-D-Ara-(1->5)-alpha-D-Ara-(1->2)-[alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)-[alpha-D-Man-(1->2)]-alpha-D-Man-(1->6)-alpha-D-Man-(1->6)-alpha-D-ManO[CH2]6N3 0
                                          alpha-D-Gal-(1->3)-beta-D-GlcNAc-(1->4)-alpha-D-GlcN6PEtn-(1->4)-[alpha-LD-Hep-(1->2)-alpha-DD-Hep-(1->2)]-alpha-D-GalA-(1->3)-[alpha-LD-Hep-(1->7)]-alpha-LD-Hep6PEtn-(1->3)-[beta-D-Glc-(1->4)]-alpha-LD-Hep-(1->5)-[alpha-Kdo-(2->4)][beta-L-Arap4N-(1->8)]-alpha-Kdo 0
                                          alpha-D-GalN-(1->4)-[alpha-DD-Hep-(1->2)]-alpha-D-GalA-(1->3)-[alpha-LD-Hep-(1->7)]-alpha-LD-Hep6PEtn-(1->3)-[beta-D-Glc-(1->4)]-alpha-LD-Hep-(1->5)-[alpha-Kdo-(2->4)][beta-L-Arap4N-(1->8)]-alpha-Kdo 0
                                          alpha-D-GalN-(1->4)-[alpha-LD-Hep-(1->2)-alpha-DD-Hep-(1->2)]-alpha-D-GalA-(1->3)-[alpha-LD-Hep-(1->7)]-alpha-LD-Hep6PEtn-(1->3)-[beta-D-Glc-(1->4)]-alpha-LD-Hep-(1->5)-[alpha-Kdo-(2->4)][beta-L-Arap4N-(1->8)]-alpha-Kdo 0
                                          alpha-D-GalNAc-(1->2)-alpha-DD-Hep-(1->6)-alpha-D-GlcNGly-(1->4)-[alpha-LD-Hep-(1->2)-alpha-DD-Hep-(1->2)]-alpha-D-GalA-(1->3)-[alpha-LD-Hep-(1->7)]-alpha-LD-Hep6PEtn-(1->3)-[beta-D-Glc-(1->4)]-alpha-LD-Hep-(1->5)-[alpha-Kdo-(2->4)][beta-L-Arap4N-(1->8)]-alpha-Kdo 0
                                          alpha-D-Galp-(1->2)-[alpha-Abep-(1->3)]-alpha-D-Manp-(1->4)-alpha-L-Rhap-(1->3)-alpha-D-Galp-(1->2)-[alpha-Abep-(1->3)]-alpha-D-Manp-(1->4)-alpha-L-Rhap-(1->3)-alpha-D-Galp-(1->2)-[alpha-Abep-(1->3)]-alpha-D-Manp-(1->4)-alpha-L-RhapOMe 0
                                          alpha-D-Glc-(1->4)-alpha-D-GalNAc-(1->2)-alpha-DD-Hep-(1->6)-alpha-D-GlcN-(1->4)-[alpha-LD-Hep-(1->2)-alpha-DD-Hep-(1->2)]-alpha-D-GalA-(1->3)-[alpha-LD-Hep-(1->7)]-alpha-LD-Hep6PEtn-(1->3)-[beta-D-Glc-(1->4)]-alpha-LD-Hep-(1->5)-[alpha-Kdo-(2->4)][beta-L-Arap4N-(1->8)]-alpha-Kdo 0
                                          alpha-D-Glc-(1->4)-alpha-D-GalNAc-(1->2)-alpha-DD-Hep-(1->6)-alpha-D-GlcNGly-(1->4)-[alpha-LD-Hep-(1->2)-alpha-DD-Hep-(1->2)]-alpha-D-GalA-(1->3)-[alpha-LD-Hep-(1->7)]-alpha-LD-Hep6PEtn-(1->3)-[beta-D-Glc-(1->4)]-alpha-LD-Hep-(1->5)-[alpha-Kdo-(2->4)][beta-L-Arap4N-(1->8)]-alpha-Kdo 0
                                          alpha-D-Glc-(1->6)-beta-D-Gal-(1->4)-(1S)-D-GaloNAc-(1->4,6)-alpha-D-GalN-(1->4)-[alpha-LD-Hep-(1->2)-alpha-DD-Hep-(1->2)]-alpha-D-GalA-(1->3)-[alpha-LD-Hep-(1->7)]-alpha-LD-Hep6PEtn-(1->3)-[beta-D-Glc-(1->4)]-alpha-LD-Hep-(1->5)-[alpha-Kdo-(2->4)][beta-L-Arap4N-(1->8)]-alpha-Kdo 0
                                          alpha-D-GlcNAc-(1->2)-alpha-D-Glc-(1->2)-alpha-D-Gal-(1->3)-[alpha-D-Gal-(1->6)]-alpha-D-Glc-(1->3)-[L-glycero-alpha-D-manno-Hep-(1->7)]-L-glycero-alpha-D-manno-Hep-(1->3)-L-glycero-D-manno-Hep 0
                                          alpha-D-GlcNAc-(1->2)-alpha-D-Glc-(1->3)-[alpha-D-Gal-(1->6)]-D-Glc-(1->3)-[LD-Hep-(1->7)]-alpha-LD-Hep4P-(1->3)-alpha-LD-Hep4PPEtN-(1->5)-alpha-D-Kdo 0
                                          alpha-D-Glcp6S-(1->4)-beta-D-Glcp6SOMe 0
                                          alpha-D-GlcpNAc-(1->4)-beta-D-Manp2NAc3NAcA-(1->3)-beta-L-FucpNAc4NMe-(1->6)-[L-alpha-D-Hepp-(1->4)]-alpha-D-GlcpN-(1->4)-[alpha-D-GalpNA-(1->6)]-beta-D-Glcp-(1->4)-\{alpha-D-GlcpN-(1->7)-[alpha-D-GlcpA-(1->2)]-D-alpha-D-Hepp-(1->3)\}-L-alpha-D-Hepp-(1->5)-alpha-Kdop 0
                                          alpha-Delta(4,5)HexpUA-(1->3)-beta-D-GalpNAc6S-(1->4)-beta-D-GlcpUA-(1->3)-beta-D-GalpNAc6S-(1->4)-beta-D-GlcpUA-(1->3)-beta-D-GalpNAc4S-(1->4)-beta-D-GlcpUA2S-(1->3)-D-GalpNAc6S 0
                                          alpha-Delta(4,5)HexpUA2S-(1->3)-beta-D-GalpNAc6S-(1->4)-beta-D-GlcpUA-(1->3)-beta-D-GalpNAc6S-(1->4)-beta-D-GlcpUA-(1->3)-beta-D-GalpNAc6S-(1->4)-beta-D-GlcpUA-(1->3)-D-GalpNAc6S 0
                                          alpha-L-Fuc-(1->2)-beta-D-Gal-(1->4)-[alpha-L-Fuc-(1->3)]-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->3)-alpha-DD-Hep-(1->3)-alpha-DD-Hep-(1->3)-alpha-DD-Hep-(1->3)-alpha-DD-Hep-(1->3)-alpha-DD-Hep-(1->6)-alpha-DD-Hep-(1->2)-alpha-DD-Hep-(1->2)-alpha-DD-Hep-O[CH2]3NH2 + 0
                                          alpha-L-Fuc3NHb-(1->4)-alpha-D-Gal-(1->6)-beta-D-Glc-(1->3)-alpha-D-GalN6PEtn-(1->4)-[alpha-LD-Hep-(1->2)-alpha-DD-Hep-(1->2)]-alpha-D-GalA-(1->3)-[alpha-LD-Hep-(1->7)]-alpha-LD-Hep6PEtn-(1->3)-[beta-D-Glc-(1->4)]-alpha-LD-Hep-(1->5)-[alpha-Kdo-(2->4)][beta-L-Arap4N-(1->8)]-alpha-Kdo 0
                                          alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->3)-beta-Gal-(1->3)-beta-GalNAc-(1->4)-[alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->3)]-beta-Gal-(1->4)-beta-Glc 0
                                          amino oligosaccharide + 2
                                          avilamycin A 0
                                          avilamycin A precursor 0
                                          beta-D-Gal-(1->4)-(1S)-D-GaloNAc-(1->4,6)-alpha-D-GalN-(1->4)-[alpha-LD-Hep-(1->2)-alpha-DD-Hep-(1->2)]-alpha-D-GalA-(1->3)-[alpha-LD-Hep-(1->7)]-alpha-LD-Hep6PEtn-(1->3)-[beta-D-Glc-(1->4)]-alpha-LD-Hep-(1->5)-[alpha-Kdo-(2->4)][beta-L-Arap4N-(1->8)]-alpha-Kdo 0
                                          beta-D-GalALys4PEtn-(1->3)-beta-D-GlcNAc-(1->6)-alpha-D-GlcNGly-(1->4)-[alpha-LD-Hep-(1->2)-alpha-DD-Hep-(1->2)]-alpha-D-GalA-(1->3)-[alpha-LD-Hep-(1->7)]-alpha-LD-Hep6PEtn-(1->3)-[beta-D-Glc-(1->4)]-alpha-LD-Hep-(1->5)-[alpha-Kdo-(2->4)][beta-L-Arap4N-(1->8)]-alpha-Kdo 0
                                          beta-D-Glc-(1->3)-alpha-D-GalN-(1->4)-[alpha-LD-Hep-(1->2)-alpha-DD-Hep-(1->2)]-alpha-D-GalA-(1->3)-[alpha-LD-Hep-(1->7)]-alpha-LD-Hep6PEtn-(1->3)-[beta-D-Glc-(1->4)]-alpha-LD-Hep-(1->5)-[alpha-Kdo-(2->4)][beta-L-Arap4N-(1->8)]-alpha-Kdo 0
                                          beta-D-Glc-(1->3)-beta-D-Glc-(1->3)-beta-D-Glc-(1->3)-beta-D-Glc-(1->3)-[beta-D-Glc-(1->3)-beta-D-Glc-(1->3)-beta-D-Glc-(1->3)-beta-D-Glc-(1->6)]-beta-D-Glc-(1->3)-beta-D-Glc-(1->3)-beta-D-Glc-(1->3)-beta-D-Glc-(1->3)-beta-D-Glc-O[CH2]2NH2 0
                                          beta-D-Glc-(1->3)-beta-D-Glc-(1->3)-beta-D-Glc-(1->3)-beta-D-Glc-(1->3)-[beta-D-Glc-(1->3)-beta-D-Glc-(1->6)]-beta-D-Glc-(1->3)-beta-D-Glc-(1->3)-beta-D-Glc-(1->3)-beta-D-Glc-(1->3)-beta-D-Glc-O[CH2]2NH2 0
                                          beta-D-Glc-(1->3)-beta-D-Glc-(1->3)-beta-D-Glc-(1->3)-beta-D-Glc-(1->3)-[beta-D-Glc-(1->6)-beta-D-Glc-(1->6)-beta-D-Glc-(1->6)-beta-D-Glc-(1->6)-beta-D-Glc-(1->6)]-beta-D-Glc-(1->3)-beta-D-Glc-(1->3)-beta-D-Glc-(1->3)-beta-D-Glc-(1->3)-beta-D-Glc-O[CH2]2NH2 0
                                          beta-D-Glc-(1->4)-alpha-D-GlcNAc-(1->4)-alpha-D-GalN6Ac(1->4)-[alpha-LD-Hep-(1->2)-alpha-DD-Hep-(1->2)]-alpha-D-GalA-(1->3)-[alpha-LD-Hep-(1->7)]-alpha-LD-Hep6PEtn-(1->3)-[beta-D-Glc-(1->4)]-alpha-LD-Hep-(1->5)-[alpha-Kdo-(2->4)][beta-L-Arap4N-(1->8)]-alpha-Kdo 0
                                          beta-D-GlcNAc-(1->3)-alpha-D-GlcN-(1->4)-[alpha-LD-Hep-(1->2)-alpha-DD-Hep-(1->2)]-alpha-D-GalA-(1->3)-[beta-D-GalAN-(1->7)-alpha-LD-Hep-(1->7)]-alpha-LD-Hep6PEtn-(1->3)-[beta-D-Glc-(1->4)]-alpha-LD-Hep-(1->5)-[alpha-Kdo-(2->4)][beta-L-Arap4N-(1->8)]-alpha-Kdo 0
                                          beta-D-GlcpNAc-(1->2)-alpha-D-Manp-(1->3)-[beta-D-GlcpNAc-(1->2)-alpha-D-Manp-(1->6)]-[beta-D-Xylp-(1->2)]-beta-D-Manp-(1->4)-beta-D-GlcpNAc-(1->4)-D-GlcpNAc + 0
                                          beta-D-GlcpNAc-(1->2)-alpha-D-Manp-(1->3)-[beta-D-GlcpNAc-(1->2)-alpha-D-Manp-(1->6)]-[beta-D-Xylp-(1->2)]-beta-D-Manp-(1->4)-beta-D-GlcpNAc-(1->4)-[alpha-L-Fucp-(1->3)]-D-GlcpNAc + 0
                                          beta-D-GlcpNAc-(1->3)-beta-D-Galp-(1->4)-beta-D-Glcp-(1->2)-alpha-D-Manp-(1->3)-[beta-D-GlcpNAc-(1->3)-beta-D-Galp-(1->4)-beta-D-Glcp-(1->2)-alpha-D-Manp-(1->6)]-beta-D-Manp-(1->4)-beta-D-GlcpNAc-(1->4)-beta-D-GlcpNAc 0
                                          decasaccharide derivative + 0
                                          dolichol-linked oligosaccharide 0
                                          heparan sulfate oligosaccharide + 0
                                          heparin oligosaccharide + 1
                                          heptasaccharide derivative + 0
                                          hexasaccharide derivative + 0
                                          lipooligosaccharide + 25
                                          mannooligosaccharide derivative + 0
                                          nonasaccharide derivative + 0
                                          octasaccharide derivative + 0
                                          oligosaccharide phosphate + 0
                                          oligosaccharide sulfate + 2
                                          pentasaccharide derivative + 17
                                          tetrasaccharide derivative + 15
                                          trisaccharide derivative + 124
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