|
|
| G
|
Ptgs2
|
prostaglandin-endoperoxide synthase 2
|
increases expression
|
ISO
|
dioctanoylphosphatidic acid results in increased expression of PTGS2 protein
|
CTD |
PMID:11854442 |
|
NCBI chr13:64,714,063...64,722,320
Ensembl chr13:64,713,619...64,722,320
|
|
|
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| G
|
Acta2
|
actin alpha 2, smooth muscle
|
increases expression multiple interactions
|
ISO
|
lysophosphatidic acid results in increased expression of ACTA2 mRNA N-(4-chlorophenyl)-1-((3-(furan-2-yl)phenyl)carbonyl)piperidine-3-carboxamide inhibits the reaction [lysophosphatidic acid results in increased expression of ACTA2 mRNA]
|
CTD |
PMID:24706986 |
|
NCBI chr 1:241,159,723...241,172,503
Ensembl chr 1:241,159,724...241,172,503
|
|
| G
|
Akt1
|
AKT serine/threonine kinase 1
|
multiple interactions increases phosphorylation
|
ISO EXP
|
2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine inhibits the reaction [lysophosphatidic acid results in increased phosphorylation of AKT1 protein]; Resveratrol inhibits the reaction [lysophosphatidic acid results in increased phosphorylation of AKT1 protein] 1-Butanol inhibits the reaction [lysophosphatidic acid results in increased phosphorylation of AKT1 protein]; exoenzyme C3, Clostridium botulinum inhibits the reaction [lysophosphatidic acid results in increased phosphorylation of AKT1 protein]
|
CTD |
PMID:14769825 PMID:17550345 PMID:20103642 |
|
NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:137,535,390...137,552,610
|
|
| G
|
Alox5
|
arachidonate 5-lipoxygenase
|
multiple interactions
|
ISO
|
ALOX5 protein promotes the reaction [lysophosphatidic acid results in increased abundance of Hydrogen Peroxide]; Masoprocol inhibits the reaction [ALOX5 protein promotes the reaction [lysophosphatidic acid results in increased abundance of Hydrogen Peroxide]]; zileuton inhibits the reaction [ALOX5 protein promotes the reaction [lysophosphatidic acid results in increased abundance of Hydrogen Peroxide]]
|
CTD |
PMID:10698703 |
|
NCBI chr 4:151,203,948...151,251,126
Ensembl chr 4:151,203,949...151,251,126
|
|
| G
|
Alpl
|
alkaline phosphatase, biomineralization associated
|
multiple interactions
|
ISO
|
[Lithocholic Acid co-treated with lysophosphatidic acid] results in increased activity of ALPL protein
|
CTD |
PMID:19646460 |
|
NCBI chr 5:155,234,770...155,289,785
Ensembl chr 5:155,234,775...155,254,167
|
|
| G
|
Bcar1
|
BCAR1 scaffold protein, Cas family member
|
increases phosphorylation
|
ISO
|
lysophosphatidic acid results in increased phosphorylation of BCAR1 protein
|
CTD |
PMID:11792571 |
|
NCBI chr19:56,588,500...56,623,190
Ensembl chr19:56,588,500...56,623,190
|
|
| G
|
Bcl2
|
BCL2, apoptosis regulator
|
increases expression
|
ISO
|
lysophosphatidic acid analog results in increased expression of BCL2 protein; lysophosphatidic acid results in increased expression of BCL2 protein
|
CTD |
PMID:23251428 |
|
NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900
|
|
| G
|
C5
|
complement C5
|
increases expression
|
ISO
|
lysophosphatidic acid results in increased expression of HC protein
|
CTD |
PMID:25822713 |
|
NCBI chr 3:38,668,174...38,759,468
Ensembl chr 3:38,668,174...38,759,468
|
|
| G
|
Casp3
|
caspase 3
|
multiple interactions
|
ISO
|
lysophosphatidic acid analog inhibits the reaction [cobaltous chloride results in increased activity of CASP3 protein]; lysophosphatidic acid inhibits the reaction [cobaltous chloride results in increased activity of CASP3 protein]
|
CTD |
PMID:23251428 |
|
NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732
|
|
| G
|
Ccl12
|
C-C motif chemokine ligand 12
|
increases expression multiple interactions
|
ISO
|
lysophosphatidic acid results in increased expression of CCL12 protein 3-(4-(4-((1-(2-chlorophenyl)ethoxy)carbonyl amino)-3-methyl-5-isoxazolyl) benzylsulfanyl) propanoic acid inhibits the reaction [lysophosphatidic acid results in increased expression of CCL12 protein]
|
CTD |
PMID:25822713 |
|
NCBI chr10:67,567,876...67,569,426
Ensembl chr10:67,567,876...67,569,426
|
|
| G
|
Ccl28
|
C-C motif chemokine ligand 28
|
multiple interactions increases expression
|
ISO
|
3-(4-(4-((1-(2-chlorophenyl)ethoxy)carbonyl amino)-3-methyl-5-isoxazolyl) benzylsulfanyl) propanoic acid inhibits the reaction [lysophosphatidic acid results in increased expression of CCL28 protein]
|
CTD |
PMID:25822713 |
|
NCBI chr 2:53,334,071...53,358,709
Ensembl chr 2:53,334,071...53,358,709
|
|
| G
|
Ccn1
|
cellular communication network factor 1
|
multiple interactions increases expression
|
ISO
|
3-(4-(4-((1-(2-chlorophenyl)ethoxy)carbonyl amino)-3-methyl-5-isoxazolyl) benzylsulfanyl) propanoic acid inhibits the reaction [lysophosphatidic acid results in increased expression of CCN1 protein]
|
CTD |
PMID:25822713 |
|
NCBI chr 2:237,222,730...237,225,689
Ensembl chr 2:237,222,432...237,225,883
|
|
| G
|
Ccn2
|
cellular communication network factor 2
|
increases expression multiple interactions
|
EXP ISO
|
lysophosphatidic acid results in increased expression of CCN2 protein N-(4-chlorophenyl)-1-((3-(furan-2-yl)phenyl)carbonyl)piperidine-3-carboxamide inhibits the reaction [lysophosphatidic acid results in increased expression of CCN2 mRNA] Simvastatin inhibits the reaction [lysophosphatidic acid results in increased expression of CCN2 protein]; Y 27632 inhibits the reaction [lysophosphatidic acid results in increased expression of CCN2 protein]
|
CTD |
PMID:15200425 PMID:24706986 |
|
NCBI chr 1:22,621,498...22,624,614
Ensembl chr 1:22,621,501...22,624,976
|
|
| G
|
Col1a2
|
collagen type I alpha 2 chain
|
increases expression multiple interactions
|
ISO
|
lysophosphatidic acid results in increased expression of COL1A2 mRNA N-(4-chlorophenyl)-1-((3-(furan-2-yl)phenyl)carbonyl)piperidine-3-carboxamide inhibits the reaction [lysophosphatidic acid results in increased expression of COL1A2 mRNA]
|
CTD |
PMID:24706986 |
|
NCBI chr 4:33,518,557...33,553,484
Ensembl chr 4:33,518,420...33,553,995
|
|
| G
|
Csf1
|
colony stimulating factor 1
|
increases expression
|
ISO
|
lysophosphatidic acid results in increased expression of CSF1 protein
|
CTD |
PMID:25822713 |
|
NCBI chr 2:198,065,400...198,084,774
Ensembl chr 2:198,065,405...198,084,468
|
|
| G
|
Cxcl12
|
C-X-C motif chemokine ligand 12
|
increases expression multiple interactions
|
ISO
|
lysophosphatidic acid results in increased expression of CXCL12 protein 3-(4-(4-((1-(2-chlorophenyl)ethoxy)carbonyl amino)-3-methyl-5-isoxazolyl) benzylsulfanyl) propanoic acid inhibits the reaction [lysophosphatidic acid results in increased expression of CXCL12 protein]
|
CTD |
PMID:25822713 |
|
NCBI chr 4:152,060,781...152,073,628
Ensembl chr 4:152,060,780...152,073,627
|
|
| G
|
Cxcl16
|
C-X-C motif chemokine ligand 16
|
increases expression multiple interactions
|
ISO
|
lysophosphatidic acid results in increased expression of CXCL16 protein 3-(4-(4-((1-(2-chlorophenyl)ethoxy)carbonyl amino)-3-methyl-5-isoxazolyl) benzylsulfanyl) propanoic acid inhibits the reaction [lysophosphatidic acid results in increased expression of CXCL16 protein]
|
CTD |
PMID:25822713 |
|
NCBI chr10:55,665,355...55,669,950
Ensembl chr10:55,664,742...55,670,226
|
|
| G
|
Cxcr1
|
C-X-C motif chemokine receptor 1
|
multiple interactions decreases expression
|
ISO
|
lysophosphatidic acid inhibits the reaction [CXCR1 protein binds to LPAR1 protein]; lysophosphatidic acid results in decreased expression of [CXCR1 protein binds to LPAR1 protein] lysophosphatidic acid results in decreased expression of CXCR1 mRNA
|
CTD |
PMID:16224106 |
|
NCBI chr 9:83,216,040...83,220,225
Ensembl chr 9:83,215,292...83,226,872
|
|
| G
|
Dgka
|
diacylglycerol kinase, alpha
|
multiple interactions
|
ISO
|
DGKA protein promotes the reaction [lysophosphatidic acid results in increased activity of PIP5K1A protein]
|
CTD |
PMID:10913605 |
|
NCBI chr 7:1,733,247...1,761,181
Ensembl chr 7:1,733,248...1,759,569
|
|
| G
|
Egfr
|
epidermal growth factor receptor
|
multiple interactions increases phosphorylation
|
ISO
|
GNA13 mutant form inhibits the reaction [lysophosphatidic acid results in increased phosphorylation of EGFR protein]; Pertussis Toxin inhibits the reaction [lysophosphatidic acid results in increased phosphorylation of EGFR protein]; resveratrol inhibits the reaction [lysophosphatidic acid results in increased phosphorylation of EGFR protein]
|
CTD |
PMID:23127547 |
|
NCBI chr14:95,378,626...95,551,358
Ensembl chr14:95,378,626...95,551,358
|
|
| G
|
Eif4ebp1
|
eukaryotic translation initiation factor 4E binding protein 1
|
multiple interactions increases phosphorylation
|
EXP
|
1-Butanol inhibits the reaction [lysophosphatidic acid results in increased phosphorylation of EIF4EBP1 protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [lysophosphatidic acid results in increased phosphorylation of EIF4EBP1 protein]; 2-butanol inhibits the reaction [lysophosphatidic acid results in increased phosphorylation of EIF4EBP1 protein]; exoenzyme C3, Clostridium botulinum inhibits the reaction [lysophosphatidic acid results in increased phosphorylation of EIF4EBP1 protein]
|
CTD |
PMID:14769825 |
|
NCBI chr16:71,495,457...71,508,845
Ensembl chr16:71,487,930...71,508,874
|
|
| G
|
Enpp2
|
ectonucleotide pyrophosphatase/phosphodiesterase 2
|
multiple interactions decreases expression
|
ISO EXP
|
1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [[ENPP2 protein co-treated with Capsaicin] results in increased abundance of lysophosphatidic acid]; 3-(2-methoxybenzylamino)-2-phenylpiperidine inhibits the reaction [[ENPP2 protein co-treated with Capsaicin] results in increased abundance of lysophosphatidic acid]; [[Capsaicin results in increased chemical synthesis of Lysophosphatidylcholines] which results in increased secretion of Lysophosphatidylcholines] promotes the reaction [ENPP2 results in increased chemical synthesis of lysophosphatidic acid]; [[ONO-8430506 results in decreased activity of ENPP2 protein] which results in decreased abundance of lysophosphatidic acid] which results in decreased expression of NFE2L2; [[ONO-8430506 results in decreased activity of ENPP2 protein] which results in decreased chemical synthesis of and results in decreased abundance of lysophosphatidic acid] which results in increased expression of ENPP2 mRNA; [ENPP2 protein co-treated with Capsaicin] results in increased abundance of lysophosphatidic acid; [ENPP2 protein co-treated with Lysophosphatidylcholines] results in increased chemical synthesis of lysophosphatidic acid; [ONO-8430506 results in decreased activity of ENPP2 protein] which results in decreased abundance of lysophosphatidic acid; [ONO-8430506 results in decreased activity of ENPP2 protein] which results in decreased chemical synthesis of and results in decreased abundance of lysophosphatidic acid; arachidonyltrifluoromethane inhibits the reaction [[ENPP2 protein co-treated with Capsaicin] results in increased abundance of lysophosphatidic acid]; bisindolylmaleimide I inhibits the reaction [[ENPP2 protein co-treated with Capsaicin] results in increased abundance of lysophosphatidic acid]; Dizocilpine Maleate inhibits the reaction [[ENPP2 protein co-treated with Capsaicin] results in increased abundance of lysophosphatidic acid]; IL1B protein inhibits the reaction [lysophosphatidic acid results in decreased expression of ENPP2 protein]; TNF protein inhibits the reaction [lysophosphatidic acid results in decreased expression of ENPP2 protein]; U 0126 inhibits the reaction [[ENPP2 protein co-treated with Capsaicin] results in increased abundance of lysophosphatidic acid]; xestospongin C inhibits the reaction [[ENPP2 protein co-treated with Capsaicin] results in increased abundance of lysophosphatidic acid] lysophosphatidic acid inhibits the reaction [ENPP2 mutant form results in decreased expression of MBP mRNA]
|
CTD |
PMID:18594965 PMID:19014389 PMID:24599971 PMID:24747415 PMID:25398768 PMID:25896349 More...
|
|
NCBI chr 7:88,092,140...88,214,758
Ensembl chr 7:88,092,140...88,214,957
|
|
| G
|
Epo
|
erythropoietin
|
multiple interactions
|
ISO
|
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [[lysophosphatidic acid co-treated with KITLG protein co-treated with EPO protein] results in increased expression of TFRC protein]; [lysophosphatidic acid co-treated with KITLG protein co-treated with EPO protein] results in increased expression of GATA1 mRNA; [lysophosphatidic acid co-treated with KITLG protein co-treated with EPO protein] results in increased expression of TFRC mRNA; [lysophosphatidic acid co-treated with KITLG protein co-treated with EPO protein] results in increased expression of TFRC protein; lysophosphatidic acid promotes the reaction [[KITLG protein co-treated with EPO protein] results in increased expression of GATA1 mRNA]; lysophosphatidic acid promotes the reaction [[KITLG protein co-treated with EPO protein] results in increased expression of GYPA mRNA]; lysophosphatidic acid promotes the reaction [[KITLG protein co-treated with EPO protein] results in increased expression of TFRC mRNA]; lysophosphatidic acid promotes the reaction [[KITLG protein co-treated with EPO protein] results in increased expression of TFRC protein]; Quercetin inhibits the reaction [[lysophosphatidic acid co-treated with KITLG protein co-treated with EPO protein] results in increased expression of GATA1 mRNA]; Quercetin inhibits the reaction [[lysophosphatidic acid co-treated with KITLG protein co-treated with EPO protein] results in increased expression of TFRC mRNA]; Quercetin inhibits the reaction [[lysophosphatidic acid co-treated with KITLG protein co-treated with EPO protein] results in increased expression of TFRC protein]; WP1066 inhibits the reaction [[lysophosphatidic acid co-treated with KITLG protein co-treated with EPO protein] results in increased expression of TFRC protein]
|
CTD |
PMID:21915944 |
|
NCBI chr12:24,841,285...24,844,725
Ensembl chr12:24,841,285...24,844,725
|
|
| G
|
Flt4
|
Fms related receptor tyrosine kinase 4
|
multiple interactions
|
ISO
|
FLT4 protein affects the reaction [lysophosphatidic acid results in increased expression of PECAM1 protein]; FLT4 protein affects the reaction [lysophosphatidic acid results in increased expression of PROX1 protein]
|
CTD |
PMID:18642114 |
|
NCBI chr10:34,414,834...34,455,878
Ensembl chr10:34,414,733...34,456,645
|
|
| G
|
Gata1
|
GATA binding protein 1
|
multiple interactions
|
ISO
|
[lysophosphatidic acid co-treated with KITLG protein co-treated with EPO protein] results in increased expression of GATA1 mRNA; lysophosphatidic acid promotes the reaction [[KITLG protein co-treated with EPO protein] results in increased expression of GATA1 mRNA]; Quercetin inhibits the reaction [[lysophosphatidic acid co-treated with KITLG protein co-treated with EPO protein] results in increased expression of GATA1 mRNA]
|
CTD |
PMID:21915944 |
|
NCBI chr X:17,193,291...17,209,462
Ensembl chr X:17,201,633...17,209,459
|
|
| G
|
Gna13
|
G protein subunit alpha 13
|
multiple interactions
|
ISO
|
GNA13 mutant form inhibits the reaction [lysophosphatidic acid results in increased phosphorylation of EGFR protein]
|
CTD |
PMID:23127547 |
|
NCBI chr10:94,837,271...94,870,290
Ensembl chr10:94,836,444...94,874,968
|
|
| G
|
Gypa
|
glycophorin A
|
multiple interactions
|
ISO
|
lysophosphatidic acid promotes the reaction [[KITLG protein co-treated with EPO protein] results in increased expression of GYPA mRNA]
|
CTD |
PMID:21915944 |
|
NCBI chr19:44,354,669...44,370,304
Ensembl chr19:44,354,706...44,370,291
|
|
| G
|
Hif1a
|
hypoxia inducible factor 1 subunit alpha
|
multiple interactions increases expression
|
ISO
|
L-4F peptide inhibits the reaction [lysophosphatidic acid results in increased expression of HIF1A protein]; resveratrol inhibits the reaction [lysophosphatidic acid results in increased expression of HIF1A protein] [lysophosphatidic acid results in increased expression of HIF1A protein] which results in increased expression of VEGFA mRNA; [lysophosphatidic acid results in increased expression of HIF1A protein] which results in increased expression of VEGFA protein; lysophosphatidic acid results in increased expression of HIF1A protein
|
CTD |
PMID:17919812 PMID:22537771 |
|
NCBI chr 6:98,357,788...98,405,068
Ensembl chr 6:98,359,910...98,405,323
|
|
| G
|
Hspb1
|
heat shock protein family B (small) member 1
|
multiple interactions increases phosphorylation
|
EXP
|
MK2i peptide inhibits the reaction [lysophosphatidic acid results in increased phosphorylation of HSPB1 protein]; SB 203580 inhibits the reaction [lysophosphatidic acid results in increased phosphorylation of HSPB1 protein]
|
CTD |
PMID:20864298 |
|
NCBI chr12:26,430,640...26,432,301
Ensembl chr12:26,430,640...26,432,301
|
|
| G
|
Il1b
|
interleukin 1 beta
|
multiple interactions
|
ISO
|
IL1B protein inhibits the reaction [lysophosphatidic acid results in decreased expression of ENPP2 protein]
|
CTD |
PMID:25896349 |
|
NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601
|
|
| G
|
Il6
|
interleukin 6
|
increases secretion
|
ISO
|
lysophosphatidic acid results in increased secretion of IL6 protein
|
CTD |
PMID:21821728 |
|
NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610
|
|
| G
|
Il6st
|
interleukin 6 cytokine family signal transducer
|
multiple interactions increases expression
|
ISO
|
3-(4-(4-((1-(2-chlorophenyl)ethoxy)carbonyl amino)-3-methyl-5-isoxazolyl) benzylsulfanyl) propanoic acid inhibits the reaction [lysophosphatidic acid results in increased expression of IL6ST protein]
|
CTD |
PMID:25822713 |
|
NCBI chr 2:45,798,872...45,839,501
Ensembl chr 2:45,799,380...45,843,182
|
|
| G
|
Kitlg
|
KIT ligand
|
multiple interactions
|
ISO
|
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [[lysophosphatidic acid co-treated with KITLG protein co-treated with EPO protein] results in increased expression of TFRC protein]; [lysophosphatidic acid co-treated with KITLG protein co-treated with EPO protein] results in increased expression of GATA1 mRNA; [lysophosphatidic acid co-treated with KITLG protein co-treated with EPO protein] results in increased expression of TFRC mRNA; [lysophosphatidic acid co-treated with KITLG protein co-treated with EPO protein] results in increased expression of TFRC protein; lysophosphatidic acid promotes the reaction [[KITLG protein co-treated with EPO protein] results in increased expression of GATA1 mRNA]; lysophosphatidic acid promotes the reaction [[KITLG protein co-treated with EPO protein] results in increased expression of GYPA mRNA]; lysophosphatidic acid promotes the reaction [[KITLG protein co-treated with EPO protein] results in increased expression of TFRC mRNA]; lysophosphatidic acid promotes the reaction [[KITLG protein co-treated with EPO protein] results in increased expression of TFRC protein]; Quercetin inhibits the reaction [[lysophosphatidic acid co-treated with KITLG protein co-treated with EPO protein] results in increased expression of GATA1 mRNA]; Quercetin inhibits the reaction [[lysophosphatidic acid co-treated with KITLG protein co-treated with EPO protein] results in increased expression of TFRC mRNA]; Quercetin inhibits the reaction [[lysophosphatidic acid co-treated with KITLG protein co-treated with EPO protein] results in increased expression of TFRC protein]; WP1066 inhibits the reaction [[lysophosphatidic acid co-treated with KITLG protein co-treated with EPO protein] results in increased expression of TFRC protein]
|
CTD |
PMID:21915944 |
|
NCBI chr 7:36,782,621...36,863,796
Ensembl chr 7:36,782,638...36,863,793
|
|
| G
|
Kng1
|
kininogen 1
|
multiple interactions
|
EXP
|
KNG1 protein inhibits the reaction [[Wortmannin co-treated with lysophosphatidic acid] results in increased phosphorylation of PTK2 protein]
|
CTD |
PMID:10537051 |
|
NCBI chr11:91,317,354...91,340,148
Ensembl chr11:91,317,355...91,340,148
|
|
| G
|
Lama3
|
laminin subunit alpha 3
|
increases expression
|
ISO
|
lysophosphatidic acid results in increased expression of LAMA3 mRNA
|
CTD |
PMID:15541073 |
|
NCBI chr18:3,797,898...4,033,021
Ensembl chr18:3,797,939...4,026,449
|
|
| G
|
Lamb3
|
laminin subunit beta 3
|
increases expression
|
ISO
|
lysophosphatidic acid results in increased expression of LAMB3 mRNA
|
CTD |
PMID:15541073 |
|
NCBI chr13:107,362,514...107,404,081
Ensembl chr13:107,322,526...107,404,081
|
|
| G
|
Lamc2
|
laminin subunit gamma 2
|
increases expression
|
ISO
|
lysophosphatidic acid results in increased expression of LAMC2 mRNA
|
CTD |
PMID:15541073 |
|
NCBI chr13:67,835,199...67,894,694
Ensembl chr13:67,835,199...67,895,102
|
|
| G
|
Lpar1
|
lysophosphatidic acid receptor 1
|
increases response to substance multiple interactions
|
ISO
|
LPAR1 protein results in increased susceptibility to lysophosphatidic acid LPAR1 protein affects the reaction [lysophosphatidic acid results in increased stability of and affects the localization of NFE2L2 protein]; lysophosphatidic acid inhibits the reaction [CXCR1 protein binds to LPAR1 protein]; lysophosphatidic acid results in decreased expression of [CXCR1 protein binds to LPAR1 protein]
|
CTD |
PMID:16224106 PMID:16809448 PMID:25398768 |
|
NCBI chr 5:78,024,139...78,147,071
Ensembl chr 5:78,024,139...78,142,188
|
|
| G
|
Lpar3
|
lysophosphatidic acid receptor 3
|
multiple interactions
|
ISO
|
Endocannabinoids inhibits the reaction [lysophosphatidic acid binds to and results in increased activity of LPAR3 protein]; lysophosphatidic acid binds to and results in increased activity of LPAR3 protein
|
CTD |
PMID:30102254 |
|
NCBI chr 2:237,785,371...237,854,199
Ensembl chr 2:237,787,766...237,854,197
|
|
| G
|
Lpar5
|
lysophosphatidic acid receptor 5
|
multiple interactions
|
ISO
|
Endocannabinoids inhibits the reaction [lysophosphatidic acid binds to and results in increased activity of LPAR5 protein]; lysophosphatidic acid binds to and results in increased activity of LPAR5 protein
|
CTD |
PMID:30102254 |
|
NCBI chr 4:159,556,735...159,570,216
Ensembl chr 4:159,554,805...159,571,894
|
|
| G
|
Lpar6
|
lysophosphatidic acid receptor 6
|
multiple interactions
|
ISO
|
lysophosphatidic acid binds to and results in increased activity of LPAR6 protein
|
CTD |
PMID:18297070 |
|
NCBI chr15:54,826,110...54,827,919
Ensembl chr15:54,823,717...54,978,783
|
|
| G
|
Lyve1
|
lymphatic vessel endothelial hyaluronan receptor 1
|
multiple interactions increases expression
|
ISO
|
3-(4-dimethylamino-naphthalen-1-ylmethylene)-1,3-dihydro-indol-2-one inhibits the reaction [lysophosphatidic acid results in increased expression of LYVE1 protein] lysophosphatidic acid results in increased expression of LYVE1 mRNA; lysophosphatidic acid results in increased expression of LYVE1 protein
|
CTD |
PMID:18642114 |
|
NCBI chr 1:174,393,387...174,410,977
|
|
| G
|
Mapk1
|
mitogen activated protein kinase 1
|
multiple interactions increases phosphorylation
|
ISO EXP
|
Hydrogen Peroxide promotes the reaction [lysophosphatidic acid results in increased phosphorylation of MAPK1 protein]; resveratrol inhibits the reaction [lysophosphatidic acid results in increased phosphorylation of MAPK1 protein] 1-Butanol inhibits the reaction [PLD1 protein affects the reaction [lysophosphatidic acid results in increased phosphorylation of MAPK1 protein]]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [lysophosphatidic acid results in increased phosphorylation of MAPK1 protein]; Pertussis Toxin inhibits the reaction [lysophosphatidic acid results in increased phosphorylation of MAPK1 protein]; PLD1 protein affects the reaction [lysophosphatidic acid results in increased phosphorylation of MAPK1 protein]; U 0126 inhibits the reaction [lysophosphatidic acid results in increased phosphorylation of MAPK1 protein]
|
CTD |
PMID:11243883 PMID:12657697 PMID:15081308 PMID:17919812 PMID:21179406 |
|
NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825
|
|
| G
|
Mapk3
|
mitogen activated protein kinase 3
|
multiple interactions increases phosphorylation
|
ISO EXP
|
Hydrogen Peroxide promotes the reaction [lysophosphatidic acid results in increased phosphorylation of MAPK3 protein]; resveratrol inhibits the reaction [lysophosphatidic acid results in increased phosphorylation of MAPK3 protein] 1-Butanol inhibits the reaction [PLD1 protein affects the reaction [lysophosphatidic acid results in increased phosphorylation of MAPK3 protein]]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [lysophosphatidic acid results in increased phosphorylation of MAPK3 protein]; Pertussis Toxin inhibits the reaction [lysophosphatidic acid results in increased phosphorylation of MAPK3 protein]; PLD1 protein affects the reaction [lysophosphatidic acid results in increased phosphorylation of MAPK3 protein]; U 0126 inhibits the reaction [lysophosphatidic acid results in increased phosphorylation of MAPK3 protein]
|
CTD |
PMID:11243883 PMID:12657697 PMID:15081308 PMID:17919812 PMID:21179406 |
|
NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:190,797,185...190,803,411
|
|
| G
|
Mbp
|
myelin basic protein
|
multiple interactions
|
EXP
|
lysophosphatidic acid inhibits the reaction [ENPP2 mutant form results in decreased expression of MBP mRNA]
|
CTD |
PMID:18594965 |
|
NCBI chr18:78,130,652...78,241,174
Ensembl chr18:78,130,325...78,241,174
|
|
| G
|
Mmp9
|
matrix metallopeptidase 9
|
multiple interactions increases expression
|
ISO
|
gefitinib inhibits the reaction [lysophosphatidic acid results in increased expression of MMP9 mRNA]; gefitinib promotes the reaction [resveratrol inhibits the reaction [lysophosphatidic acid results in increased expression of MMP9 mRNA]]; resveratrol inhibits the reaction [lysophosphatidic acid results in increased expression of MMP9 mRNA]; resveratrol promotes the reaction [gefitinib inhibits the reaction [lysophosphatidic acid results in increased expression of MMP9 mRNA]]
|
CTD |
PMID:23127547 |
|
NCBI chr 3:174,103,474...174,111,434
Ensembl chr 3:174,084,123...174,111,442
|
|
| G
|
Mtor
|
mechanistic target of rapamycin kinase
|
increases phosphorylation
|
EXP
|
lysophosphatidic acid results in increased phosphorylation of MTOR protein
|
CTD |
PMID:14769825 |
|
NCBI chr 5:164,167,985...164,277,438
Ensembl chr 5:164,167,928...164,277,435
|
|
| G
|
Myl9
|
myosin light chain 9
|
increases phosphorylation multiple interactions
|
ISO
|
lysophosphatidic acid results in increased phosphorylation of MYL9 protein Farnesol analog inhibits the reaction [lysophosphatidic acid results in increased phosphorylation of MYL9 protein]; geranylgeraniol analog inhibits the reaction [lysophosphatidic acid results in increased phosphorylation of MYL9 protein]
|
CTD |
PMID:24587105 |
|
NCBI chr 3:165,742,020...165,748,409
Ensembl chr 3:165,742,046...165,748,410
|
|
| G
|
Mylk
|
myosin light chain kinase
|
affects response to substance
|
ISO
|
MYLK protein affects the susceptibility to lysophosphatidic acid
|
CTD |
PMID:10640419 |
|
NCBI chr11:79,288,243...79,535,450
Ensembl chr11:79,288,243...79,535,659
|
|
| G
|
Nfe2l2
|
NFE2 like bZIP transcription factor 2
|
multiple interactions
|
ISO
|
LPAR1 protein affects the reaction [lysophosphatidic acid results in increased stability of and affects the localization of NFE2L2 protein]; lysophosphatidic acid results in increased stability of and affects the localization of NFE2L2 protein [[ONO-8430506 results in decreased activity of ENPP2 protein] which results in decreased abundance of lysophosphatidic acid] which results in decreased expression of NFE2L2
|
CTD |
PMID:25398768 |
|
NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:81,001,529...81,029,090
|
|
| G
|
Nppa
|
natriuretic peptide A
|
multiple interactions increases expression
|
EXP
|
Pertussis Toxin inhibits the reaction [lysophosphatidic acid results in increased expression of NPPA protein]; Y 27632 inhibits the reaction [lysophosphatidic acid results in increased expression of NPPA protein]
|
CTD |
PMID:15081308 PMID:25449040 |
|
NCBI chr 5:163,712,184...163,713,493
Ensembl chr 5:163,712,184...163,713,493
|
|
| G
|
Pak1
|
p21 (RAC1) activated kinase 1
|
increases activity multiple interactions
|
EXP
|
lysophosphatidic acid results in increased activity of PAK1 protein 4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [lysophosphatidic acid results in increased activity of PAK1 protein]; diphenyleneiodonium inhibits the reaction [lysophosphatidic acid results in increased activity of PAK1 protein]; Genistein inhibits the reaction [lysophosphatidic acid results in increased activity of PAK1 protein]; Pertussis Toxin inhibits the reaction [lysophosphatidic acid results in increased activity of PAK1 protein]
|
CTD |
PMID:11855845 |
|
NCBI chr 1:161,522,399...161,637,623
Ensembl chr 1:161,491,847...161,637,612
|
|
| G
|
Pdpn
|
podoplanin
|
increases expression multiple interactions
|
ISO
|
lysophosphatidic acid results in increased expression of PDPN mRNA; lysophosphatidic acid results in increased expression of PDPN protein 3-(4-dimethylamino-naphthalen-1-ylmethylene)-1,3-dihydro-indol-2-one inhibits the reaction [lysophosphatidic acid results in increased expression of PDPN protein]
|
CTD |
PMID:18642114 |
|
NCBI chr 5:160,884,995...160,919,112
Ensembl chr 5:160,884,993...160,925,637
|
|
| G
|
Pecam1
|
platelet and endothelial cell adhesion molecule 1
|
increases expression multiple interactions
|
ISO
|
lysophosphatidic acid results in increased expression of PECAM1 protein 3-(4-dimethylamino-naphthalen-1-ylmethylene)-1,3-dihydro-indol-2-one inhibits the reaction [lysophosphatidic acid results in increased expression of PECAM1 protein]; FLT4 protein affects the reaction [lysophosphatidic acid results in increased expression of PECAM1 protein]
|
CTD |
PMID:18642114 |
|
NCBI chr10:92,090,263...92,152,002
Ensembl chr10:92,090,235...92,151,839
|
|
| G
|
Pip5k1a
|
phosphatidylinositol-4-phosphate 5-kinase, type 1, alpha
|
multiple interactions increases activity
|
ISO
|
1-Butanol inhibits the reaction [lysophosphatidic acid results in increased activity of PIP5K1A protein]; DGKA protein promotes the reaction [lysophosphatidic acid results in increased activity of PIP5K1A protein]
|
CTD |
PMID:10913605 |
|
NCBI chr 2:185,317,319...185,361,859
Ensembl chr 2:185,317,319...185,360,476
|
|
| G
|
Plau
|
plasminogen activator, urokinase
|
multiple interactions increases expression
|
ISO
|
gefitinib inhibits the reaction [lysophosphatidic acid results in increased expression of PLAU mRNA]; gefitinib promotes the reaction [resveratrol inhibits the reaction [lysophosphatidic acid results in increased expression of PLAU mRNA]]; resveratrol inhibits the reaction [lysophosphatidic acid results in increased expression of PLAU mRNA]; resveratrol promotes the reaction [gefitinib inhibits the reaction [lysophosphatidic acid results in increased expression of PLAU mRNA]]
|
CTD |
PMID:23127547 |
|
NCBI chr15:3,505,485...3,511,987
Ensembl chr15:3,505,487...3,512,030
|
|
| G
|
Pld1
|
phospholipase D1
|
multiple interactions increases activity
|
EXP
|
1-Butanol inhibits the reaction [PLD1 protein affects the reaction [lysophosphatidic acid results in increased phosphorylation of MAPK1 protein]]; 1-Butanol inhibits the reaction [PLD1 protein affects the reaction [lysophosphatidic acid results in increased phosphorylation of MAPK3 protein]]; bisindolylmaleimide I inhibits the reaction [lysophosphatidic acid results in increased activity of PLD1 protein]; Pertussis Toxin inhibits the reaction [lysophosphatidic acid results in increased activity of PLD1 protein]; PLD1 protein affects the reaction [lysophosphatidic acid results in increased phosphorylation of MAPK1 protein]; PLD1 protein affects the reaction [lysophosphatidic acid results in increased phosphorylation of MAPK3 protein]; toxB protein, Clostridium difficile inhibits the reaction [lysophosphatidic acid results in increased phosphorylation of PLD1 protein]
|
CTD |
PMID:11243883 PMID:14769825 |
|
NCBI chr 2:112,777,820...112,975,857
Ensembl chr 2:112,777,951...112,976,245
|
|
| G
|
Ppp1r12a
|
protein phosphatase 1, regulatory subunit 12A
|
increases phosphorylation multiple interactions
|
EXP
|
lysophosphatidic acid results in increased phosphorylation of PPP1R12A protein Y 27632 inhibits the reaction [lysophosphatidic acid results in increased phosphorylation of PPP1R12A protein]
|
CTD |
PMID:25449040 |
|
NCBI chr 7:45,368,922...45,480,158
Ensembl chr 7:45,369,315...45,480,157
|
|
| G
|
Prox1
|
prospero homeobox 1
|
increases expression multiple interactions
|
ISO
|
lysophosphatidic acid results in increased expression of PROX1 mRNA; lysophosphatidic acid results in increased expression of PROX1 protein 3-(4-dimethylamino-naphthalen-1-ylmethylene)-1,3-dihydro-indol-2-one inhibits the reaction [lysophosphatidic acid results in increased expression of PROX1 protein]; FLT4 protein affects the reaction [lysophosphatidic acid results in increased expression of PROX1 protein]
|
CTD |
PMID:18642114 |
|
NCBI chr13:104,196,615...104,251,007
Ensembl chr13:104,200,378...104,250,975
|
|
| G
|
Ptk2
|
protein tyrosine kinase 2
|
increases phosphorylation multiple interactions
|
ISO EXP
|
lysophosphatidic acid results in increased phosphorylation of PTK2 protein [wortmannin co-treated with lysophosphatidic acid] results in increased phosphorylation of PTK2 protein; KNG1 protein inhibits the reaction [[wortmannin co-treated with lysophosphatidic acid] results in increased phosphorylation of PTK2 protein] [wortmannin co-treated with lysophosphatidic acid] results in increased phosphorylation of PTK2 protein; Atropine inhibits the reaction [oxotremorine M inhibits the reaction [[wortmannin co-treated with lysophosphatidic acid] results in increased phosphorylation of PTK2 protein]]; oxotremorine M inhibits the reaction [[wortmannin co-treated with lysophosphatidic acid] results in increased phosphorylation of PTK2 protein]
|
CTD |
PMID:10537051 PMID:11792571 |
|
NCBI chr 7:107,015,730...107,220,865
Ensembl chr 7:107,015,733...107,172,091
|
|
| G
|
Ptk2b
|
protein tyrosine kinase 2 beta
|
increases phosphorylation
|
ISO
|
lysophosphatidic acid results in increased phosphorylation of PTK2B protein
|
CTD |
PMID:11792571 |
|
NCBI chr15:44,536,275...44,656,754
Ensembl chr15:44,531,249...44,656,806
|
|
| G
|
Rhoa
|
ras homolog family member A
|
increases activity multiple interactions
|
EXP ISO
|
lysophosphatidic acid results in increased activity of RHOA protein Farnesol analog inhibits the reaction [lysophosphatidic acid results in increased activity of RHOA protein]; geranylgeraniol analog inhibits the reaction [lysophosphatidic acid results in increased activity of RHOA protein]
|
CTD |
PMID:15081308 PMID:24587105 |
|
NCBI chr 8:117,870,548...117,904,303
Ensembl chr 8:117,870,270...117,904,302
|
|
| G
|
Rhoc
|
ras homolog family member C
|
multiple interactions increases activity
|
ISO
|
Farnesol analog inhibits the reaction [lysophosphatidic acid results in increased activity of RHOC protein]; geranylgeraniol analog inhibits the reaction [lysophosphatidic acid results in increased activity of RHOC protein]
|
CTD |
PMID:24587105 |
|
NCBI chr 2:194,975,586...194,981,637
Ensembl chr 2:194,975,242...194,983,745
|
|
| G
|
Rps6kb1
|
ribosomal protein S6 kinase B1
|
increases phosphorylation multiple interactions
|
ISO EXP
|
lysophosphatidic acid results in increased phosphorylation of RPS6KB1 protein resveratrol inhibits the reaction [lysophosphatidic acid results in increased phosphorylation of RPS6KB1 protein] 1-Butanol inhibits the reaction [lysophosphatidic acid results in increased phosphorylation of RPS6KB1 protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [lysophosphatidic acid results in increased phosphorylation of RPS6KB1 protein]; exoenzyme C3, Clostridium botulinum inhibits the reaction [lysophosphatidic acid results in increased phosphorylation of RPS6KB1 protein]
|
CTD |
PMID:14769825 PMID:17919812 |
|
NCBI chr10:71,817,794...71,865,211
Ensembl chr10:71,815,614...71,865,238
|
|
| G
|
Tfrc
|
transferrin receptor
|
multiple interactions
|
ISO
|
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [[lysophosphatidic acid co-treated with KITLG protein co-treated with EPO protein] results in increased expression of TFRC protein]; [lysophosphatidic acid co-treated with KITLG protein co-treated with EPO protein] results in increased expression of TFRC mRNA; [lysophosphatidic acid co-treated with KITLG protein co-treated with EPO protein] results in increased expression of TFRC protein; lysophosphatidic acid promotes the reaction [[KITLG protein co-treated with EPO protein] results in increased expression of TFRC mRNA]; lysophosphatidic acid promotes the reaction [[KITLG protein co-treated with EPO protein] results in increased expression of TFRC protein]; Quercetin inhibits the reaction [[lysophosphatidic acid co-treated with KITLG protein co-treated with EPO protein] results in increased expression of TFRC mRNA]; Quercetin inhibits the reaction [[lysophosphatidic acid co-treated with KITLG protein co-treated with EPO protein] results in increased expression of TFRC protein]; WP1066 inhibits the reaction [[lysophosphatidic acid co-treated with KITLG protein co-treated with EPO protein] results in increased expression of TFRC protein]
|
CTD |
PMID:21915944 |
|
NCBI chr11:81,668,478...81,690,318
Ensembl chr11:81,668,478...81,690,318
|
|
| G
|
Timp1
|
TIMP metallopeptidase inhibitor 1
|
multiple interactions increases expression
|
ISO
|
3-(4-(4-((1-(2-chlorophenyl)ethoxy)carbonyl amino)-3-methyl-5-isoxazolyl) benzylsulfanyl) propanoic acid inhibits the reaction [lysophosphatidic acid results in increased expression of TIMP1 protein]
|
CTD |
PMID:25822713 |
|
NCBI chr X:3,766,509...3,772,578
Ensembl chr X:3,766,510...3,771,135
|
|
| G
|
Tnf
|
tumor necrosis factor
|
multiple interactions
|
ISO
|
TNF protein inhibits the reaction [lysophosphatidic acid results in decreased expression of ENPP2 protein]
|
CTD |
PMID:25896349 |
|
NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303
|
|
| G
|
Vegfa
|
vascular endothelial growth factor A
|
increases expression multiple interactions
|
ISO
|
[lysophosphatidic acid results in increased expression of HIF1A protein] which results in increased expression of VEGFA mRNA; [lysophosphatidic acid results in increased expression of HIF1A protein] which results in increased expression of VEGFA protein resveratrol inhibits the reaction [lysophosphatidic acid results in increased expression of VEGFA protein]
|
CTD |
PMID:17919812 |
|
NCBI chr 9:22,452,854...22,468,194
Ensembl chr 9:22,439,392...22,468,194
|
|
| G
|
Vegfc
|
vascular endothelial growth factor C
|
increases expression increases secretion
|
ISO
|
lysophosphatidic acid results in increased expression of VEGFC mRNA lysophosphatidic acid results in increased secretion of VEGFC protein
|
CTD |
PMID:18642114 |
|
NCBI chr16:44,445,293...44,560,887
Ensembl chr16:44,445,293...44,560,887
|
|
|
|
| G
|
App
|
amyloid beta precursor protein
|
multiple interactions decreases abundance
|
ISO
|
PF-06840003 inhibits the reaction [APP protein mutant form results in decreased abundance of alpha-glycerophosphoric acid] [APP protein mutant form co-treated with PSEN1 protein mutant form] results in decreased abundance of alpha-glycerophosphoric acid; IDO1 protein affects the reaction [[APP protein mutant form co-treated with PSEN1 protein mutant form] results in decreased abundance of alpha-glycerophosphoric acid]; PF-06840003 inhibits the reaction [[APP protein mutant form co-treated with PSEN1 protein mutant form] results in decreased abundance of alpha-glycerophosphoric acid]
|
CTD |
PMID:39172838 |
|
NCBI chr11:37,506,207...37,724,351
Ensembl chr11:37,506,408...37,722,971
|
|
| G
|
Gk
|
glycerol kinase
|
multiple interactions
|
EXP
|
1-butyrylglycerol promotes the reaction [[GK protein results in increased metabolism of Glycerol] which results in increased chemical synthesis of alpha-glycerophosphoric acid]; [GK protein results in increased metabolism of Glycerol] which results in increased chemical synthesis of alpha-glycerophosphoric acid; monoacetin promotes the reaction [[GK protein results in increased metabolism of Glycerol] which results in increased chemical synthesis of alpha-glycerophosphoric acid]
|
CTD |
PMID:9606984 |
|
NCBI chr X:54,106,708...54,189,940
Ensembl chr X:54,112,214...54,196,701
|
|
| G
|
Gpd2
|
glycerol-3-phosphate dehydrogenase 2
|
multiple interactions
|
ISO
|
GPD2 protein inhibits the reaction [Dihydroxyacetone results in increased abundance of alpha-glycerophosphoric acid]; GPD2 protein inhibits the reaction [Glucose results in increased abundance of alpha-glycerophosphoric acid]; GPD2 protein inhibits the reaction [Glycerol results in increased abundance of alpha-glycerophosphoric acid]
|
CTD |
PMID:31974165 |
|
NCBI chr 3:62,209,432...62,346,590
Ensembl chr 3:62,210,814...62,346,593
|
|
| G
|
Idh2
|
isocitrate dehydrogenase (NADP(+)) 2
|
multiple interactions increases abundance
|
ISO
|
Triazines inhibits the reaction [IDH2 protein mutant form results in increased abundance of alpha-glycerophosphoric acid]
|
CTD |
PMID:27469509 |
|
NCBI chr 1:143,447,925...143,467,248
Ensembl chr 1:143,439,323...143,467,248
|
|
| G
|
Ido1
|
indoleamine 2,3-dioxygenase 1
|
multiple interactions
|
ISO
|
IDO1 protein affects the reaction [[APP protein mutant form co-treated with PSEN1 protein mutant form] results in decreased abundance of alpha-glycerophosphoric acid]
|
CTD |
PMID:39172838 |
|
NCBI chr16:74,133,259...74,145,328
Ensembl chr16:74,133,259...74,145,328
|
|
| G
|
Mapt
|
microtubule-associated protein tau
|
decreases abundance multiple interactions
|
ISO
|
MAPT protein mutant form results in decreased abundance of alpha-glycerophosphoric acid PF-06840003 inhibits the reaction [MAPT protein mutant form results in decreased abundance of alpha-glycerophosphoric acid]
|
CTD |
PMID:39172838 |
|
NCBI chr10:89,638,618...89,736,108
Ensembl chr10:89,638,599...89,736,108
|
|
| G
|
Psen1
|
presenilin 1
|
multiple interactions
|
ISO
|
[APP protein mutant form co-treated with PSEN1 protein mutant form] results in decreased abundance of alpha-glycerophosphoric acid; IDO1 protein affects the reaction [[APP protein mutant form co-treated with PSEN1 protein mutant form] results in decreased abundance of alpha-glycerophosphoric acid]; PF-06840003 inhibits the reaction [[APP protein mutant form co-treated with PSEN1 protein mutant form] results in decreased abundance of alpha-glycerophosphoric acid]
|
CTD |
PMID:39172838 |
|
NCBI chr 6:109,054,160...109,106,191
Ensembl chr 6:109,060,352...109,106,189
|
|
| G
|
Runx2
|
RUNX family transcription factor 2
|
multiple interactions
|
ISO
|
[SAG compound co-treated with 2,4-di-tert-butylphenol co-treated with Fibroblast Growth Factor 2 co-treated with Ascorbic Acid co-treated with alpha-glycerophosphoric acid co-treated with Dexamethasone] results in decreased expression of RUNX2 mRNA
|
CTD |
PMID:36682590 |
|
NCBI chr 9:23,661,278...23,990,248
Ensembl chr 9:23,664,952...23,990,027
|
|
| G
|
Sp7
|
Sp7 transcription factor
|
multiple interactions
|
ISO
|
[SAG compound co-treated with 2,4-di-tert-butylphenol co-treated with Fibroblast Growth Factor 2 co-treated with Ascorbic Acid co-treated with alpha-glycerophosphoric acid co-treated with Dexamethasone] results in decreased expression of SP7 mRNA
|
CTD |
PMID:36682590 |
|
NCBI chr 7:135,363,193...135,373,376
Ensembl chr 7:135,363,199...135,373,559
|
|
| G
|
Spp1
|
secreted phosphoprotein 1
|
multiple interactions
|
ISO
|
[SAG compound co-treated with 2,4-di-tert-butylphenol co-treated with Fibroblast Growth Factor 2 co-treated with Ascorbic Acid co-treated with alpha-glycerophosphoric acid co-treated with Dexamethasone] results in increased expression of SPP1 mRNA
|
CTD |
PMID:36682590 |
|
NCBI chr14:5,613,569...5,620,695
Ensembl chr14:5,613,576...5,619,820
|
|
|
|
| G
|
Abca1
|
ATP binding cassette subfamily A member 1
|
multiple interactions
|
ISO
|
[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of ABCA1 mRNA; [Bexarotene co-treated with [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein]] results in increased expression of ABCA1 protein; [diazepinylbenzoic acid co-treated with [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein]] results in decreased expression of ABCA1 mRNA; [LG 100268 co-treated with [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein]] results in increased expression of ABCA1 mRNA; [Rosiglitazone co-treated with [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein]] results in increased expression of ABCA1 protein; [T0901317 co-treated with [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein]] results in increased expression of ABCA1 mRNA; [tributyltin co-treated with [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein]] results in increased expression of ABCA1 mRNA; [tributyltin co-treated with [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein]] results in increased expression of ABCA1 protein; diazepinylbenzoic acid inhibits the reaction [[LG 100268 co-treated with [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein]] results in increased expression of ABCA1 mRNA]; diazepinylbenzoic acid inhibits the reaction [[tributyltin co-treated with [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein]] results in increased expression of ABCA1 mRNA]
|
CTD |
PMID:25932594 |
|
NCBI chr 5:72,473,676...72,596,563
Ensembl chr 5:72,473,676...72,596,473
|
|
| G
|
Akt1
|
AKT serine/threonine kinase 1
|
multiple interactions
|
ISO
|
[Dexamethasone co-treated with ascorbate-2-phosphate co-treated with beta-glycerophosphoric acid] results in increased phosphorylation of AKT1 protein; dorsomorphin inhibits the reaction [[Dexamethasone co-treated with ascorbate-2-phosphate co-treated with beta-glycerophosphoric acid] results in increased phosphorylation of AKT1 protein]
|
CTD |
PMID:23111315 |
|
NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:137,535,390...137,552,610
|
|
| G
|
Alpl
|
alkaline phosphatase, biomineralization associated
|
increases hydrolysis multiple interactions increases expression increases degradation increases activity
|
ISO
|
ALPL protein results in increased hydrolysis of beta-glycerophosphoric acid [ALPL protein results in increased degradation of beta-glycerophosphoric acid] which results in increased abundance of Phosphates; [Ascorbic Acid co-treated with Dexamethasone co-treated with beta-glycerophosphoric acid] results in increased expression of ALPL mRNA; [beta-glycerophosphoric acid co-treated with Ascorbic Acid] results in increased expression of ALPL mRNA; [Dexamethasone co-treated with Ascorbic Acid co-treated with beta-glycerophosphoric acid] affects the expression of ALPL mRNA; Diethylhexyl Phthalate affects the reaction [[Dexamethasone co-treated with Ascorbic Acid co-treated with beta-glycerophosphoric acid] affects the expression of ALPL mRNA]; Diphosphates inhibits the reaction [[ALPL protein results in increased degradation of beta-glycerophosphoric acid] which results in increased abundance of Phosphates]; Diphosphates inhibits the reaction [ALPL protein results in increased degradation of beta-glycerophosphoric acid]; mono-(2-ethylhexyl)phthalate affects the reaction [[Dexamethasone co-treated with Ascorbic Acid co-treated with beta-glycerophosphoric acid] affects the expression of ALPL mRNA]; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [[Ascorbic Acid co-treated with Dexamethasone co-treated with beta-glycerophosphoric acid] results in increased expression of ALPL mRNA]; Particulate Matter inhibits the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid] results in increased expression of ALPL mRNA] beta-glycerophosphoric acid results in increased expression of ALPL mRNA beta-glycerophosphoric acid results in increased activity of ALPL protein [ALPL protein results in increased hydrolysis of beta-glycerophosphoric acid] which results in increased abundance of Phosphates; [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in increased expression of ALPL mRNA; [Dexamethasone co-treated with ascorbate-2-phosphate co-treated with beta-glycerophosphoric acid] results in increased activity of ALPL protein; cordycepin inhibits the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [[Dexamethasone co-treated with ascorbate-2-phosphate co-treated with beta-glycerophosphoric acid] results in increased activity of ALPL protein]]; EZH2 protein inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in increased expression of ALPL mRNA]; Levamisole inhibits the reaction [beta-glycerophosphoric acid results in increased activity of ALPL protein]; Levamisole inhibits the reaction [beta-glycerophosphoric acid results in increased expression of ALPL mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Dexamethasone co-treated with ascorbate-2-phosphate co-treated with beta-glycerophosphoric acid] results in increased activity of ALPL protein]
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CTD |
PMID:17383965 PMID:18500657 PMID:26424790 PMID:26492236 PMID:28921615 PMID:34575692 PMID:38914176 More...
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NCBI chr 5:155,234,770...155,289,785
Ensembl chr 5:155,234,775...155,254,167
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| G
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Atad2
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ATPase family, AAA domain containing 2
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multiple interactions
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ISO
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[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in decreased expression of ATAD2 mRNA
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CTD |
PMID:26424790 |
|
NCBI chr 7:91,523,626...91,566,238
Ensembl chr 7:91,523,626...91,566,238
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| G
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Atad2b
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ATPase family, AAA domain containing 2B
|
multiple interactions
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ISO
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[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in increased expression of ATAD2B mRNA
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CTD |
PMID:26424790 |
|
NCBI chr 6:33,646,075...33,789,532
Ensembl chr 6:33,646,075...33,789,532
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| G
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Becn1
|
beclin 1
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multiple interactions
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ISO
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[Dexamethasone co-treated with ascorbate-2-phosphate co-treated with beta-glycerophosphoric acid] results in increased expression of BECN1 protein
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CTD |
PMID:23111315 |
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NCBI chr10:86,731,649...86,747,002
Ensembl chr10:86,731,650...86,747,002
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| G
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Bglap
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bone gamma-carboxyglutamate protein
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multiple interactions
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ISO EXP
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[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of BGLAP mRNA; [Cholecalciferol co-treated with beta-glycerophosphoric acid co-treated with Ascorbic Acid] results in increased expression of BGLAP protein; [Dexamethasone co-treated with ascorbate-2-phosphate co-treated with beta-glycerophosphoric acid] results in increased expression of BGLAP mRNA; [Rutin co-treated with Dexamethasone co-treated with ascorbate-2-phosphate co-treated with beta-glycerophosphoric acid] results in increased secretion of BGLAP protein; Ammonium Chloride inhibits the reaction [[Dexamethasone co-treated with ascorbate-2-phosphate co-treated with beta-glycerophosphoric acid] results in increased expression of BGLAP mRNA]; bafilomycin A1 inhibits the reaction [[Dexamethasone co-treated with ascorbate-2-phosphate co-treated with beta-glycerophosphoric acid] results in increased expression of BGLAP mRNA]; Bexarotene inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of BGLAP mRNA]; Chloroquine inhibits the reaction [[Dexamethasone co-treated with ascorbate-2-phosphate co-treated with beta-glycerophosphoric acid] results in increased expression of BGLAP mRNA]; cordycepin inhibits the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [[Dexamethasone co-treated with ascorbate-2-phosphate co-treated with beta-glycerophosphoric acid] results in increased expression of BGLAP mRNA]]; dorsomorphin inhibits the reaction [[Dexamethasone co-treated with ascorbate-2-phosphate co-treated with beta-glycerophosphoric acid] results in increased expression of BGLAP mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Dexamethasone co-treated with ascorbate-2-phosphate co-treated with beta-glycerophosphoric acid] results in increased expression of BGLAP mRNA]; Rosiglitazone inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of BGLAP mRNA]; Sirolimus inhibits the reaction [[Dexamethasone co-treated with ascorbate-2-phosphate co-treated with beta-glycerophosphoric acid] results in increased expression of BGLAP mRNA]; tributyltin inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of BGLAP mRNA] 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [[[Dexamethasone co-treated with beta-glycerophosphoric acid co-treated with Ascorbic Acid] co-treated with fasudil] results in increased expression of BGLAP mRNA]; 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [[[Dexamethasone co-treated with beta-glycerophosphoric acid co-treated with Ascorbic Acid] co-treated with fasudil] results in increased expression of BGLAP protein]; [[Dexamethasone co-treated with beta-glycerophosphoric acid co-treated with Ascorbic Acid] co-treated with fasudil] results in increased expression of BGLAP mRNA; [[Dexamethasone co-treated with beta-glycerophosphoric acid co-treated with Ascorbic Acid] co-treated with fasudil] results in increased expression of BGLAP protein; [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of BGLAP mRNA; [Ascorbic Acid co-treated with Dexamethasone co-treated with beta-glycerophosphoric acid] results in increased expression of BGLAP mRNA; [Ascorbic Acid co-treated with Dexamethasone co-treated with beta-glycerophosphoric acid] results in increased expression of BGLAP protein; [beta-glycerophosphoric acid co-treated with Ascorbic Acid] results in increased expression of BGLAP mRNA; [Dexamethasone co-treated with Ascorbic Acid co-treated with beta-glycerophosphoric acid] affects the expression of BGLAP mRNA; Allethrins inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of BGLAP mRNA]; d,d-T80-prallethrin inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of BGLAP mRNA]; Diethylhexyl Phthalate affects the reaction [[Dexamethasone co-treated with Ascorbic Acid co-treated with beta-glycerophosphoric acid] affects the expression of BGLAP mRNA]; mono-(2-ethylhexyl)phthalate affects the reaction [[Dexamethasone co-treated with Ascorbic Acid co-treated with beta-glycerophosphoric acid] affects the expression of BGLAP mRNA]; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [[Ascorbic Acid co-treated with Dexamethasone co-treated with beta-glycerophosphoric acid] results in increased expression of BGLAP mRNA]; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [[Ascorbic Acid co-treated with Dexamethasone co-treated with beta-glycerophosphoric acid] results in increased expression of BGLAP protein]; Particulate Matter inhibits the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid] results in increased expression of BGLAP mRNA]; Pioglitazone inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of BGLAP mRNA]; quinoxyfen inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of BGLAP mRNA]; Rosiglitazone inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of BGLAP mRNA]; SMAD4 protein inhibits the reaction [Particulate Matter inhibits the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid] results in increased expression of BGLAP mRNA]]; Tretinoin inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of BGLAP mRNA]; triphenyltin hydroxide inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of BGLAP mRNA] [beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] affects the expression of BGLAP mRNA; Hydrogen Peroxide affects the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] affects the expression of BGLAP mRNA]; Quercetin affects the reaction [Hydrogen Peroxide affects the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] affects the expression of BGLAP mRNA]]
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CTD |
PMID:17692823 PMID:23111315 PMID:25932594 PMID:26492236 PMID:27028516 PMID:28921615 PMID:31935364 PMID:32473317 PMID:34562440 PMID:34575692 PMID:38914176 More...
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NCBI chr 2:176,136,341...176,137,318
Ensembl chr 2:176,136,341...176,137,318
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| G
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Bmp1
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bone morphogenetic protein 1
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multiple interactions
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EXP
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[Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of BMP1 mRNA
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CTD |
PMID:15994055 |
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NCBI chr15:51,961,310...52,005,597
Ensembl chr15:51,961,310...52,005,485
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| G
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Bmp2
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bone morphogenetic protein 2
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multiple interactions
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EXP ISO
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[Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of BMP2 mRNA; [Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of BMP2 protein; Dexamethasone inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of BMP2 protein]; ginsenoside Rg3 inhibits the reaction [Dexamethasone inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of BMP2 protein]]; NOG protein inhibits the reaction [ginsenoside Rg3 inhibits the reaction [Dexamethasone inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of BMP2 protein]]] [Dexamethasone co-treated with ascorbate-2-phosphate co-treated with beta-glycerophosphoric acid co-treated with Cholecalciferol] results in increased expression of BMP2 mRNA; [Dexamethasone co-treated with ascorbate-2-phosphate co-treated with beta-glycerophosphoric acid] results in increased expression of BMP2 mRNA; MAP1LC3B protein affects the reaction [[Dexamethasone co-treated with ascorbate-2-phosphate co-treated with beta-glycerophosphoric acid] results in increased expression of BMP2 mRNA]; PARG mRNA promotes the reaction [[Dexamethasone co-treated with ascorbate-2-phosphate co-treated with beta-glycerophosphoric acid co-treated with Cholecalciferol] results in increased expression of BMP2 mRNA]; Sirolimus inhibits the reaction [[Dexamethasone co-treated with ascorbate-2-phosphate co-treated with beta-glycerophosphoric acid] results in increased expression of BMP2 mRNA] [Ascorbic Acid co-treated with Dexamethasone co-treated with beta-glycerophosphoric acid] results in increased expression of BMP2 mRNA; [Ascorbic Acid co-treated with Dexamethasone co-treated with beta-glycerophosphoric acid] results in increased expression of BMP2 protein; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [[Ascorbic Acid co-treated with Dexamethasone co-treated with beta-glycerophosphoric acid] results in increased expression of BMP2 mRNA]; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [[Ascorbic Acid co-treated with Dexamethasone co-treated with beta-glycerophosphoric acid] results in increased expression of BMP2 protein]
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CTD |
PMID:15994055 PMID:22940495 PMID:23111315 PMID:26492236 PMID:27387537 |
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NCBI chr 3:141,264,648...141,275,416
Ensembl chr 3:141,264,646...141,274,760
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| G
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Bmp3
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bone morphogenetic protein 3
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multiple interactions
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EXP
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[Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of BMP3 mRNA
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CTD |
PMID:15994055 |
|
NCBI chr14:11,012,564...11,041,282
Ensembl chr14:11,016,620...11,041,282
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| G
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Bmp7
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bone morphogenetic protein 7
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multiple interactions
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EXP
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[Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of BMP7 mRNA
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CTD |
PMID:15994055 |
|
NCBI chr 3:182,059,318...182,135,273
Ensembl chr 3:182,052,337...182,135,137
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| G
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Bmpr1a
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bone morphogenetic protein receptor type 1A
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multiple interactions
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EXP
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[Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of BMPR1A protein; Dexamethasone inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of BMPR1A protein]; ginsenoside Rg3 inhibits the reaction [Dexamethasone inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of BMPR1A protein]]; NOG protein inhibits the reaction [ginsenoside Rg3 inhibits the reaction [Dexamethasone inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of BMPR1A protein]]]
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CTD |
PMID:27387537 |
|
NCBI chr16:9,740,751...9,786,861
Ensembl chr16:9,742,875...9,786,861
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| G
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Cebpa
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CCAAT/enhancer binding protein alpha
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multiple interactions
|
ISO
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[Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of CEBPA protein [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of CEBPA mRNA
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CTD |
PMID:14505802 PMID:25932594 |
|
NCBI chr 1:96,896,584...96,899,256
Ensembl chr 1:96,896,171...96,899,309
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| G
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Chaf1b
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chromatin assembly factor 1 subunit B
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multiple interactions
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ISO
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[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in decreased expression of CHAF1B mRNA
|
CTD |
PMID:26424790 |
|
NCBI chr11:46,670,560...46,690,739
Ensembl chr11:46,670,630...46,690,733
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| G
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Cited1
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Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 1
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multiple interactions
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ISO
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[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in increased expression of CITED1 mRNA; cadmium sulfate inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in increased expression of CITED1 mRNA]
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CTD |
PMID:28189605 |
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NCBI chr X:71,390,328...71,395,023
Ensembl chr X:71,390,331...71,393,649
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| G
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Col1a1
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collagen type I alpha 1 chain
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multiple interactions
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ISO
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4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [[[Dexamethasone co-treated with beta-glycerophosphoric acid co-treated with Ascorbic Acid] co-treated with fasudil] results in increased expression of COL1A1 mRNA]; [[Dexamethasone co-treated with beta-glycerophosphoric acid co-treated with Ascorbic Acid] co-treated with fasudil] results in increased expression of COL1A1 mRNA [Dexamethasone co-treated with ascorbate-2-phosphate co-treated with beta-glycerophosphoric acid] results in increased expression of COL1A1 mRNA; [Rutin co-treated with Dexamethasone co-treated with ascorbate-2-phosphate co-treated with beta-glycerophosphoric acid] results in increased expression of COL1A1 mRNA; cordycepin inhibits the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [[Dexamethasone co-treated with ascorbate-2-phosphate co-treated with beta-glycerophosphoric acid] results in increased expression of COL1A1 mRNA]]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Dexamethasone co-treated with ascorbate-2-phosphate co-treated with beta-glycerophosphoric acid] results in increased expression of COL1A1 mRNA]
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CTD |
PMID:31935364 PMID:34562440 PMID:34575692 |
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NCBI chr10:80,380,458...80,397,461
Ensembl chr10:80,380,453...80,397,460
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| G
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Ctnnb1
|
catenin beta 1
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multiple interactions
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ISO
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[Dexamethasone co-treated with beta-glycerophosphoric acid co-treated with ascorbate-2-phosphate] results in increased expression of CTNNB1 mRNA; lead nitrate inhibits the reaction [[Dexamethasone co-treated with beta-glycerophosphoric acid co-treated with ascorbate-2-phosphate] results in increased expression of CTNNB1 mRNA] [Dexamethasone co-treated with Ascorbic Acid co-treated with beta-glycerophosphoric acid] affects the expression of CTNNB1 mRNA; [Dexamethasone co-treated with Ascorbic Acid co-treated with beta-glycerophosphoric acid] affects the phosphorylation of CTNNB1 protein; Diethylhexyl Phthalate affects the reaction [[Dexamethasone co-treated with Ascorbic Acid co-treated with beta-glycerophosphoric acid] affects the expression of CTNNB1 mRNA]; Diethylhexyl Phthalate affects the reaction [[Dexamethasone co-treated with Ascorbic Acid co-treated with beta-glycerophosphoric acid] affects the phosphorylation of CTNNB1 protein]; Lithium Chloride affects the reaction [Diethylhexyl Phthalate affects the reaction [[Dexamethasone co-treated with Ascorbic Acid co-treated with beta-glycerophosphoric acid] affects the phosphorylation of CTNNB1 protein]]; Lithium Chloride affects the reaction [mono-(2-ethylhexyl)phthalate affects the reaction [[Dexamethasone co-treated with Ascorbic Acid co-treated with beta-glycerophosphoric acid] affects the phosphorylation of CTNNB1 protein]]; mono-(2-ethylhexyl)phthalate affects the reaction [[Dexamethasone co-treated with Ascorbic Acid co-treated with beta-glycerophosphoric acid] affects the expression of CTNNB1 mRNA]; mono-(2-ethylhexyl)phthalate affects the reaction [[Dexamethasone co-treated with Ascorbic Acid co-treated with beta-glycerophosphoric acid] affects the phosphorylation of CTNNB1 protein]; T 0070907 affects the reaction [Diethylhexyl Phthalate affects the reaction [[Dexamethasone co-treated with Ascorbic Acid co-treated with beta-glycerophosphoric acid] affects the phosphorylation of CTNNB1 protein]]; T 0070907 affects the reaction [mono-(2-ethylhexyl)phthalate affects the reaction [[Dexamethasone co-treated with Ascorbic Acid co-treated with beta-glycerophosphoric acid] affects the phosphorylation of CTNNB1 protein]]
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CTD |
PMID:28921615 PMID:35738543 |
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NCBI chr 8:129,517,576...129,544,661
Ensembl chr 8:129,517,545...129,544,662
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| G
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Dmp1
|
dentin matrix acidic phosphoprotein 1
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multiple interactions
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ISO
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[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of DMP1 mRNA; [Dexamethasone co-treated with beta-glycerophosphoric acid co-treated with ascorbate-2-phosphate] results in increased expression of DMP1 mRNA; Bexarotene inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of DMP1 mRNA]; lead nitrate inhibits the reaction [[Dexamethasone co-treated with beta-glycerophosphoric acid co-treated with ascorbate-2-phosphate] results in increased expression of DMP1 mRNA]; Rosiglitazone inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of DMP1 mRNA]; tributyltin inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of DMP1 mRNA]
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CTD |
PMID:25932594 PMID:35738543 |
|
NCBI chr14:5,833,111...5,867,154
Ensembl chr14:5,833,111...5,843,993
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| G
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Dpf1
|
double PHD fingers 1
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multiple interactions
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ISO
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[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in decreased expression of DPF1 mRNA
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CTD |
PMID:26424790 |
|
NCBI chr 1:93,729,683...93,743,425
Ensembl chr 1:93,726,970...93,743,425
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| G
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Dppa2
|
developmental pluripotency-associated 2
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multiple interactions
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ISO
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[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in decreased expression of DPPA2 mRNA
|
CTD |
PMID:28189605 |
|
NCBI chr11:66,008,002...66,020,044
Ensembl chr11:66,011,628...66,020,994
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| G
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Dspp
|
dentin sialophosphoprotein
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multiple interactions
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ISO
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[Dexamethasone co-treated with beta-glycerophosphoric acid co-treated with ascorbate-2-phosphate] results in increased expression of DSPP mRNA; lead nitrate inhibits the reaction [[Dexamethasone co-treated with beta-glycerophosphoric acid co-treated with ascorbate-2-phosphate] results in increased expression of DSPP mRNA]
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CTD |
PMID:35738543 |
|
NCBI chr14:5,870,232...5,876,339
Ensembl chr14:5,870,232...5,876,339
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| G
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Enpp1
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ectonucleotide pyrophosphatase/phosphodiesterase 1
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increases expression multiple interactions increases activity
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ISO
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beta-glycerophosphoric acid results in increased expression of ENPP1 mRNA Levamisole inhibits the reaction [beta-glycerophosphoric acid results in increased activity of ENPP1 protein]; Levamisole inhibits the reaction [beta-glycerophosphoric acid results in increased expression of ENPP1 mRNA]
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CTD |
PMID:18500657 |
|
NCBI chr 1:22,518,051...22,583,044
Ensembl chr 1:22,518,069...22,583,044
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| G
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Esr1
|
estrogen receptor 1
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multiple interactions
|
ISO
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[Dexamethasone co-treated with Ascorbic Acid co-treated with beta-glycerophosphoric acid] affects the expression of ESR1 protein; Diethylhexyl Phthalate affects the reaction [[Dexamethasone co-treated with Ascorbic Acid co-treated with beta-glycerophosphoric acid] affects the expression of ESR1 protein]; mono-(2-ethylhexyl)phthalate affects the reaction [[Dexamethasone co-treated with Ascorbic Acid co-treated with beta-glycerophosphoric acid] affects the expression of ESR1 protein]
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CTD |
PMID:28921615 |
|
NCBI chr 1:43,511,685...43,904,454
Ensembl chr 1:43,644,392...43,900,354
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|
| G
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Ezh1
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enhancer of zeste 1 polycomb repressive complex 2 subunit
|
multiple interactions
|
ISO
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[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in increased expression of EZH1 mRNA
|
CTD |
PMID:26424790 |
|
NCBI chr10:86,626,307...86,662,257
Ensembl chr10:86,626,308...86,652,620
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| G
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Ezh2
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enhancer of zeste 2 polycomb repressive complex 2 subunit
|
multiple interactions
|
ISO
|
[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in decreased expression of EZH2 mRNA; [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in decreased expression of EZH2 protein; EZH2 protein inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in increased expression of ALPL mRNA]; EZH2 protein inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in increased expression of RUNX2 mRNA]; EZH2 protein inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in increased expression of SATB2 mRNA]; EZH2 protein inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in increased expression of TNFRSF11B mRNA]
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CTD |
PMID:26424790 |
|
NCBI chr 4:77,624,223...77,698,598
Ensembl chr 4:77,624,223...77,687,183
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|
| G
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Fabp4
|
fatty acid binding protein 4
|
multiple interactions
|
ISO
|
[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of FABP4 mRNA; [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS1 protein co-treated with Firemaster 550] results in increased expression of FABP4 mRNA; [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS1 protein co-treated with triphenyl phosphate] results in increased expression of FABP4 mRNA; d,d-T80-prallethrin promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of FABP4 mRNA]; Pioglitazone promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of FABP4 mRNA]; Rosiglitazone promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of FABP4 mRNA]; tetrabromobisphenol A promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of FABP4 mRNA]; triphenyltin hydroxide promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of FABP4 mRNA]
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CTD |
PMID:25062436 PMID:25932594 PMID:32473317 |
|
NCBI chr 2:93,488,251...93,492,961
Ensembl chr 2:93,488,271...93,492,972
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|
| G
|
Fancl
|
FA complementation group L
|
multiple interactions
|
ISO
|
[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in decreased expression of FANCL mRNA
|
CTD |
PMID:26424790 |
|
NCBI chr14:104,449,403...104,515,297
Ensembl chr14:104,394,590...104,515,297
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|
| G
|
Fgf23
|
fibroblast growth factor 23
|
increases expression
|
ISO
|
beta-glycerophosphoric acid results in increased expression of FGF23 mRNA
|
CTD |
PMID:15542045 |
|
NCBI chr 4:161,600,439...161,609,991
Ensembl chr 4:161,600,383...161,609,991
|
|
| G
|
Gclc
|
glutamate-cysteine ligase, catalytic subunit
|
multiple interactions
|
EXP
|
[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] affects the expression of GCLC mRNA; Hydrogen Peroxide affects the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] affects the expression of GCLC mRNA]; Quercetin affects the reaction [Hydrogen Peroxide affects the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] affects the expression of GCLC mRNA]]
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CTD |
PMID:27028516 |
|
NCBI chr 8:87,510,251...87,548,896
Ensembl chr 8:87,510,463...87,548,893
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|
| G
|
Gdf10
|
growth differentiation factor 10
|
multiple interactions
|
EXP
|
[Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of GDF10 mRNA
|
CTD |
PMID:15994055 |
|
NCBI chr16:9,243,434...9,256,788
Ensembl chr16:9,243,317...9,256,794
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|
| G
|
Gpc3
|
glypican 3
|
multiple interactions
|
ISO
|
[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in increased expression of GPC3 mRNA; cadmium sulfate inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in increased expression of GPC3 mRNA]
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CTD |
PMID:28189605 |
|
NCBI chr X:136,789,770...137,157,598
Ensembl chr X:136,789,770...137,157,639
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|
| G
|
H2ax
|
H2A.X variant histone
|
multiple interactions
|
ISO
|
[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in decreased expression of H2AX mRNA
|
CTD |
PMID:26424790 |
|
NCBI chr 8:53,568,718...53,570,072
Ensembl chr 8:53,568,281...53,573,079
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|
| G
|
Hand2
|
heart and neural crest derivatives expressed 2
|
multiple interactions
|
ISO
|
[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in increased expression of HAND2 mRNA; cadmium sulfate inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in increased expression of HAND2 mRNA]
|
CTD |
PMID:28189605 |
|
NCBI chr16:37,928,145...37,931,488
Ensembl chr16:37,928,145...37,931,488
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|
| G
|
Hells
|
helicase, lymphoid specific
|
multiple interactions
|
ISO
|
[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in decreased expression of HELLS mRNA
|
CTD |
PMID:26424790 |
|
NCBI chr 1:246,113,580...246,159,230
Ensembl chr 1:246,114,096...246,159,228
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|
| G
|
Hmgb1
|
high mobility group box 1
|
multiple interactions
|
ISO
|
[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in decreased expression of HMGB1 mRNA
|
CTD |
PMID:26424790 |
|
NCBI chr12:11,009,236...11,015,941
Ensembl chr16:39,039,050...39,041,327 Ensembl chr12:39,039,050...39,041,327
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|
| G
|
Hmgb2
|
high mobility group box 2
|
multiple interactions
|
ISO
|
[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in decreased expression of HMGB2 mRNA
|
CTD |
PMID:26424790 |
|
NCBI chr16:37,721,374...37,723,950
Ensembl chr16:37,721,379...37,723,860
|
|
| G
|
Hmox1
|
heme oxygenase 1
|
multiple interactions
|
EXP
|
[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] affects the expression of HMOX1 mRNA; [beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] affects the expression of HMOX1 protein; Hydrogen Peroxide affects the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] affects the expression of HMOX1 mRNA]; Hydrogen Peroxide affects the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] affects the expression of HMOX1 protein]; Hydrogen Peroxide affects the reaction [Quercetin affects the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] affects the expression of HMOX1 mRNA]]; Hydrogen Peroxide affects the reaction [Quercetin affects the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] affects the expression of HMOX1 protein]]; Quercetin affects the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] affects the expression of HMOX1 mRNA]; Quercetin affects the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] affects the expression of HMOX1 protein]; Quercetin affects the reaction [Hydrogen Peroxide affects the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] affects the expression of HMOX1 protein]]
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CTD |
PMID:27028516 |
|
NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,472,884...13,479,818
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|
| G
|
Ibsp
|
integrin-binding sialoprotein
|
multiple interactions
|
EXP ISO
|
[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] affects the expression of IBSP mRNA; Hydrogen Peroxide affects the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] affects the expression of IBSP mRNA]; Quercetin affects the reaction [Hydrogen Peroxide affects the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] affects the expression of IBSP mRNA]] [Ascorbic Acid co-treated with Dexamethasone co-treated with beta-glycerophosphoric acid] results in increased expression of IBSP mRNA; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [[Ascorbic Acid co-treated with Dexamethasone co-treated with beta-glycerophosphoric acid] results in increased expression of IBSP mRNA]
|
CTD |
PMID:26492236 PMID:27028516 |
|
NCBI chr14:5,744,497...5,757,242
Ensembl chr14:5,744,501...5,775,299
|
|
| G
|
Ins1
|
insulin 1
|
multiple interactions
|
ISO
|
[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS1 protein co-treated with Firemaster 550] results in decreased expression of SP7 mRNA; [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS1 protein co-treated with Firemaster 550] results in increased expression of FABP4 mRNA; [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS1 protein co-treated with triphenyl phosphate] results in decreased expression of SP7 mRNA; [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS1 protein co-treated with triphenyl phosphate] results in increased expression of FABP4 mRNA
|
CTD |
PMID:25062436 |
|
NCBI chr 1:261,186,119...261,186,686
Ensembl chr 1:261,186,119...261,186,682
|
|
| G
|
Ins2
|
insulin 2
|
multiple interactions
|
ISO
|
[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of ABCA1 mRNA; [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of BGLAP mRNA; [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of CEBPA mRNA; [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of DMP1 mRNA; [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of FABP4 mRNA; [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of NR1H3 mRNA; [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of PLIN1 mRNA; [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of PPARG mRNA; [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SP7 mRNA; [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SREBF1 mRNA; [Bexarotene co-treated with [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein]] results in increased expression of ABCA1 protein; [diazepinylbenzoic acid co-treated with [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein]] results in decreased expression of ABCA1 mRNA; [LG 100268 co-treated with [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein]] results in increased expression of ABCA1 mRNA; [Rosiglitazone co-treated with [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein]] results in increased expression of ABCA1 protein; [T0901317 co-treated with [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein]] results in increased expression of ABCA1 mRNA; [tributyltin co-treated with [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein]] results in increased expression of ABCA1 mRNA; [tributyltin co-treated with [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein]] results in increased expression of ABCA1 protein; Bexarotene inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of BGLAP mRNA]; Bexarotene inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of DMP1 mRNA]; Bexarotene inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SP7 mRNA]; Bexarotene promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of NR1H3 mRNA]; Bexarotene promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SREBF1 mRNA]; diazepinylbenzoic acid inhibits the reaction [[LG 100268 co-treated with [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein]] results in increased expression of ABCA1 mRNA]; diazepinylbenzoic acid inhibits the reaction [[tributyltin co-treated with [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein]] results in increased expression of ABCA1 mRNA]; Rosiglitazone inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of BGLAP mRNA]; Rosiglitazone inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of DMP1 mRNA]; Rosiglitazone inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SP7 mRNA]; Rosiglitazone promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of NR1H3 mRNA]; Rosiglitazone promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SREBF1 mRNA]; tributyltin inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of BGLAP mRNA]; tributyltin inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of DMP1 mRNA]; tributyltin inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SP7 mRNA]; tributyltin promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of NR1H3 mRNA]; tributyltin promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SREBF1 mRNA] [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of BGLAP mRNA; [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of FABP4 mRNA; [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of PLIN1 mRNA; [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of PPARG mRNA; [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of RUNX2 mRNA; [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SP7 mRNA; Allethrins inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of BGLAP mRNA]; Allethrins inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SP7 mRNA]; d,d-T80-prallethrin inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of BGLAP mRNA]; d,d-T80-prallethrin inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SP7 mRNA]; d,d-T80-prallethrin promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of FABP4 mRNA]; Pioglitazone inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of BGLAP mRNA]; Pioglitazone inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SP7 mRNA]; Pioglitazone promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of FABP4 mRNA]; Pioglitazone promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of PLIN1 mRNA]; quinoxyfen inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of BGLAP mRNA]; quinoxyfen inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SP7 mRNA]; Rosiglitazone inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of BGLAP mRNA]; Rosiglitazone inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of RUNX2 mRNA]; Rosiglitazone inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SP7 mRNA]; Rosiglitazone promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of FABP4 mRNA]; Rosiglitazone promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of PLIN1 mRNA]; Rosiglitazone promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of PPARG mRNA]; tetrabromobisphenol A inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SP7 mRNA]; tetrabromobisphenol A promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of FABP4 mRNA]; tetrabromobisphenol A promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of PLIN1 mRNA]; Tretinoin inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of BGLAP mRNA]; Tretinoin inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of PLIN1 mRNA]; Tretinoin inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of PPARG mRNA]; Tretinoin inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SP7 mRNA]; triphenyltin hydroxide inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of BGLAP mRNA]; triphenyltin hydroxide inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SP7 mRNA]; triphenyltin hydroxide promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of FABP4 mRNA]; triphenyltin hydroxide promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of PLIN1 mRNA]
|
CTD |
PMID:25932594 PMID:32473317 |
|
NCBI chr 1:207,272,738...207,421,998
Ensembl chr 1:207,272,742...207,273,805
|
|
| G
|
Map1lc3b
|
microtubule-associated protein 1 light chain 3 beta
|
multiple interactions
|
ISO
|
MAP1LC3B protein affects the reaction [[Dexamethasone co-treated with ascorbate-2-phosphate co-treated with beta-glycerophosphoric acid] results in increased expression of BMP2 mRNA]; MAP1LC3B protein affects the reaction [[Dexamethasone co-treated with ascorbate-2-phosphate co-treated with beta-glycerophosphoric acid] results in increased expression of RUNX2 mRNA]
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CTD |
PMID:23111315 |
|
NCBI chr19:66,571,631...66,582,270
Ensembl chr19:66,574,407...66,584,358 Ensembl chr16:66,574,407...66,584,358
|
|
| G
|
Msx2
|
msh homeobox 2
|
multiple interactions
|
ISO
|
[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in increased expression of MSX2 mRNA; cadmium sulfate inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in increased expression of MSX2 mRNA]
|
CTD |
PMID:28189605 |
|
NCBI chr17:11,102,284...11,107,949
Ensembl chr17:11,102,247...11,107,945
|
|
| G
|
Mtor
|
mechanistic target of rapamycin kinase
|
multiple interactions
|
ISO
|
[Dexamethasone co-treated with ascorbate-2-phosphate co-treated with beta-glycerophosphoric acid] affects the phosphorylation of MTOR protein; dorsomorphin inhibits the reaction [[Dexamethasone co-treated with ascorbate-2-phosphate co-treated with beta-glycerophosphoric acid] affects the phosphorylation of MTOR protein]; MTOR protein affects the reaction [[Dexamethasone co-treated with ascorbate-2-phosphate co-treated with beta-glycerophosphoric acid] affects the phosphorylation of RPS6KB1 protein]; Sirolimus inhibits the reaction [[Dexamethasone co-treated with ascorbate-2-phosphate co-treated with beta-glycerophosphoric acid] affects the phosphorylation of MTOR protein]
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CTD |
PMID:23111315 |
|
NCBI chr 5:164,167,985...164,277,438
Ensembl chr 5:164,167,928...164,277,435
|
|
| G
|
Nog
|
noggin
|
multiple interactions
|
EXP
|
NOG protein inhibits the reaction [ginsenoside Rg3 inhibits the reaction [Dexamethasone inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of BMP2 protein]]]; NOG protein inhibits the reaction [ginsenoside Rg3 inhibits the reaction [Dexamethasone inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of BMPR1A protein]]]; NOG protein inhibits the reaction [ginsenoside Rg3 inhibits the reaction [Dexamethasone inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of RUNX2 protein]]]
|
CTD |
PMID:27387537 |
|
NCBI chr10:74,625,874...74,627,501
Ensembl chr10:74,625,875...74,628,103
|
|
| G
|
Nr1h3
|
nuclear receptor subfamily 1, group H, member 3
|
multiple interactions
|
ISO
|
[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of NR1H3 mRNA; bexarotene promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of NR1H3 mRNA]; rosiglitazone promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of NR1H3 mRNA]; tributyltin promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of NR1H3 mRNA]
|
CTD |
PMID:25932594 |
|
NCBI chr 3:97,614,616...97,632,053
Ensembl chr 3:97,614,616...97,624,532
|
|
| G
|
Nsd2
|
nuclear receptor binding SET domain protein 2
|
multiple interactions
|
ISO
|
[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in decreased expression of NSD2 mRNA
|
CTD |
PMID:26424790 |
|
NCBI chr14:81,057,727...81,135,866
Ensembl chr14:81,057,727...81,123,027
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|
| G
|
Parg
|
poly (ADP-ribose) glycohydrolase
|
multiple interactions
|
ISO
|
PARG mRNA inhibits the reaction [[Dexamethasone co-treated with ascorbate-2-phosphate co-treated with beta-glycerophosphoric acid co-treated with Cholecalciferol] results in increased expression of PARP1 protein]; PARG mRNA inhibits the reaction [[Dexamethasone co-treated with ascorbate-2-phosphate co-treated with beta-glycerophosphoric acid co-treated with Cholecalciferol] results in increased expression of SPP1 mRNA]; PARG mRNA promotes the reaction [[Dexamethasone co-treated with ascorbate-2-phosphate co-treated with beta-glycerophosphoric acid co-treated with Cholecalciferol] results in increased expression of BMP2 mRNA]; PARG mRNA promotes the reaction [[Dexamethasone co-treated with ascorbate-2-phosphate co-treated with beta-glycerophosphoric acid co-treated with Cholecalciferol] results in increased expression of RUNX2 mRNA]
|
CTD |
PMID:22940495 |
|
NCBI chr16:7,442,696...7,550,585
Ensembl chr16:7,442,726...7,550,584
|
|
| G
|
Parp1
|
poly (ADP-ribose) polymerase 1
|
multiple interactions
|
ISO
|
[Ascorbic Acid co-treated with Dexamethasone co-treated with beta-glycerophosphoric acid] results in increased expression of PARP1 mRNA; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [[Ascorbic Acid co-treated with Dexamethasone co-treated with beta-glycerophosphoric acid] results in increased expression of PARP1 mRNA] [Dexamethasone co-treated with ascorbate-2-phosphate co-treated with beta-glycerophosphoric acid co-treated with Cholecalciferol] results in increased expression of PARP1 protein modified form; PARG mRNA inhibits the reaction [[Dexamethasone co-treated with ascorbate-2-phosphate co-treated with beta-glycerophosphoric acid co-treated with Cholecalciferol] results in increased expression of PARP1 protein]; PARP1 mRNA promotes the reaction [[Dexamethasone co-treated with ascorbate-2-phosphate co-treated with beta-glycerophosphoric acid co-treated with Cholecalciferol] results in increased expression of RUNX2 mRNA]
|
CTD |
PMID:22940495 PMID:26492236 |
|
NCBI chr13:94,839,484...94,871,295
Ensembl chr13:94,839,433...94,871,567
|
|
| G
|
Phex
|
phosphate regulating endopeptidase X-linked
|
increases expression multiple interactions
|
ISO
|
beta-glycerophosphoric acid results in increased expression of PHEX mRNA Foscarnet inhibits the reaction [beta-glycerophosphoric acid results in increased expression of PHEX mRNA]; Levamisole inhibits the reaction [beta-glycerophosphoric acid results in increased expression of PHEX mRNA]
|
CTD |
PMID:18500657 |
|
NCBI chr X:41,422,561...41,671,226
Ensembl chr X:41,426,101...41,671,226
|
|
| G
|
Phf2
|
PHD finger protein 2
|
multiple interactions
|
ISO
|
[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in increased expression of PHF2 mRNA
|
CTD |
PMID:26424790 |
|
NCBI chr17:15,989,594...16,057,583
Ensembl chr17:15,981,604...16,057,583
|
|
| G
|
Plin1
|
perilipin 1
|
multiple interactions
|
ISO
|
[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of PLIN1 mRNA [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of PLIN1 mRNA; Pioglitazone promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of PLIN1 mRNA]; Rosiglitazone promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of PLIN1 mRNA]; tetrabromobisphenol A promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of PLIN1 mRNA]; Tretinoin inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of PLIN1 mRNA]; triphenyltin hydroxide promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of PLIN1 mRNA]
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CTD |
PMID:25932594 PMID:32473317 |
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NCBI chr 1:143,073,612...143,086,199
Ensembl chr 1:143,074,214...143,086,206
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| G
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Pou5f1
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POU class 5 homeobox 1
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multiple interactions
|
ISO
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[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in decreased expression of POU5F1 mRNA
|
CTD |
PMID:28189605 |
|
NCBI chr20:3,227,836...3,232,598
Ensembl chr20:3,227,837...3,232,598
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| G
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Pparg
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peroxisome proliferator-activated receptor gamma
|
multiple interactions
|
ISO
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[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of PPARG mRNA; [Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of PPARG mRNA; Rosiglitazone promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of PPARG mRNA]; SRC protein promotes the reaction [Tetrachlorodibenzodioxin inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of PPARG mRNA]]; Tetrachlorodibenzodioxin inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of PPARG mRNA]; Tretinoin inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of PPARG mRNA]
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CTD |
PMID:14505802 PMID:25932594 PMID:32473317 |
|
NCBI chr 4:150,095,743...150,221,104
Ensembl chr 4:150,095,787...150,221,104
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| G
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Pth1r
|
parathyroid hormone 1 receptor
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multiple interactions
|
ISO
|
[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in increased expression of PTH1R mRNA; cadmium sulfate inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in increased expression of PTH1R mRNA]
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CTD |
PMID:28189605 |
|
NCBI chr 8:119,572,295...119,597,405
Ensembl chr 8:119,575,868...119,598,108
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| G
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Rps6kb1
|
ribosomal protein S6 kinase B1
|
multiple interactions
|
ISO
|
[Dexamethasone co-treated with ascorbate-2-phosphate co-treated with beta-glycerophosphoric acid] affects the phosphorylation of RPS6KB1 protein; dorsomorphin inhibits the reaction [[Dexamethasone co-treated with ascorbate-2-phosphate co-treated with beta-glycerophosphoric acid] affects the phosphorylation of RPS6KB1 protein]; MTOR protein affects the reaction [[Dexamethasone co-treated with ascorbate-2-phosphate co-treated with beta-glycerophosphoric acid] affects the phosphorylation of RPS6KB1 protein]; Sirolimus inhibits the reaction [[Dexamethasone co-treated with ascorbate-2-phosphate co-treated with beta-glycerophosphoric acid] affects the phosphorylation of RPS6KB1 protein]
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CTD |
PMID:23111315 |
|
NCBI chr10:71,817,794...71,865,211
Ensembl chr10:71,815,614...71,865,238
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| G
|
Rptor
|
regulatory associated protein of MTOR, complex 1
|
multiple interactions
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ISO
|
[Dexamethasone co-treated with ascorbate-2-phosphate co-treated with beta-glycerophosphoric acid] results in increased phosphorylation of RPTOR protein
|
CTD |
PMID:23111315 |
|
NCBI chr10:105,376,943...105,675,416
Ensembl chr10:105,376,943...105,675,413
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|
| G
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Runx2
|
RUNX family transcription factor 2
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multiple interactions increases expression
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ISO EXP
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[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in increased expression of RUNX2 mRNA; [Cholecalciferol co-treated with beta-glycerophosphoric acid co-treated with Ascorbic Acid] results in increased expression of RUNX2 mRNA; [Dexamethasone co-treated with ascorbate-2-phosphate co-treated with beta-glycerophosphoric acid co-treated with Cholecalciferol] results in increased expression of RUNX2 mRNA; [Dexamethasone co-treated with ascorbate-2-phosphate co-treated with beta-glycerophosphoric acid] results in increased expression of RUNX2 mRNA; [Dexamethasone co-treated with beta-glycerophosphoric acid co-treated with ascorbate-2-phosphate] results in increased expression of RUNX2 mRNA; [Rutin co-treated with Dexamethasone co-treated with ascorbate-2-phosphate co-treated with beta-glycerophosphoric acid] results in increased expression of RUNX2 mRNA; Ammonium Chloride inhibits the reaction [[Dexamethasone co-treated with ascorbate-2-phosphate co-treated with beta-glycerophosphoric acid] results in increased expression of RUNX2 mRNA]; bafilomycin A1 inhibits the reaction [[Dexamethasone co-treated with ascorbate-2-phosphate co-treated with beta-glycerophosphoric acid] results in increased expression of RUNX2 mRNA]; bisphenol A inhibits the reaction [beta-glycerophosphoric acid results in increased expression of RUNX2 protein]; Chloroquine inhibits the reaction [[Dexamethasone co-treated with ascorbate-2-phosphate co-treated with beta-glycerophosphoric acid] results in increased expression of RUNX2 mRNA]; cordycepin inhibits the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [[Dexamethasone co-treated with ascorbate-2-phosphate co-treated with beta-glycerophosphoric acid] results in increased expression of RUNX2 mRNA]]; dorsomorphin inhibits the reaction [[Dexamethasone co-treated with ascorbate-2-phosphate co-treated with beta-glycerophosphoric acid] results in increased expression of RUNX2 mRNA]; EZH2 protein inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in increased expression of RUNX2 mRNA]; lead nitrate inhibits the reaction [[Dexamethasone co-treated with beta-glycerophosphoric acid co-treated with ascorbate-2-phosphate] results in increased expression of RUNX2 mRNA]; MAP1LC3B protein affects the reaction [[Dexamethasone co-treated with ascorbate-2-phosphate co-treated with beta-glycerophosphoric acid] results in increased expression of RUNX2 mRNA]; PARG mRNA promotes the reaction [[Dexamethasone co-treated with ascorbate-2-phosphate co-treated with beta-glycerophosphoric acid co-treated with Cholecalciferol] results in increased expression of RUNX2 mRNA]; PARP1 mRNA promotes the reaction [[Dexamethasone co-treated with ascorbate-2-phosphate co-treated with beta-glycerophosphoric acid co-treated with Cholecalciferol] results in increased expression of RUNX2 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Dexamethasone co-treated with ascorbate-2-phosphate co-treated with beta-glycerophosphoric acid] results in increased expression of RUNX2 mRNA]; Sirolimus inhibits the reaction [[Dexamethasone co-treated with ascorbate-2-phosphate co-treated with beta-glycerophosphoric acid] results in increased expression of RUNX2 mRNA] 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [[[Dexamethasone co-treated with beta-glycerophosphoric acid co-treated with Ascorbic Acid] co-treated with fasudil] results in increased expression of RUNX2 mRNA]; 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [[[Dexamethasone co-treated with beta-glycerophosphoric acid co-treated with Ascorbic Acid] co-treated with fasudil] results in increased expression of RUNX2 protein]; [[Dexamethasone co-treated with beta-glycerophosphoric acid co-treated with Ascorbic Acid] co-treated with fasudil] results in increased expression of RUNX2 mRNA; [[Dexamethasone co-treated with beta-glycerophosphoric acid co-treated with Ascorbic Acid] co-treated with fasudil] results in increased expression of RUNX2 protein; [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of RUNX2 mRNA; [Ascorbic Acid co-treated with Dexamethasone co-treated with beta-glycerophosphoric acid] results in increased expression of RUNX2 mRNA; [beta-glycerophosphoric acid co-treated with Ascorbic Acid] results in increased expression of RUNX2 mRNA; [beta-glycerophosphoric acid co-treated with Ascorbic Acid] results in increased expression of RUNX2 protein; [Dexamethasone co-treated with Ascorbic Acid co-treated with beta-glycerophosphoric acid] affects the expression of RUNX2 mRNA; [Dexamethasone co-treated with Ascorbic Acid co-treated with beta-glycerophosphoric acid] affects the expression of RUNX2 protein; [Folic Acid co-treated with Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of RUNX2 protein; Diethylhexyl Phthalate affects the reaction [[Dexamethasone co-treated with Ascorbic Acid co-treated with beta-glycerophosphoric acid] affects the expression of RUNX2 mRNA]; Diethylhexyl Phthalate affects the reaction [[Dexamethasone co-treated with Ascorbic Acid co-treated with beta-glycerophosphoric acid] affects the expression of RUNX2 protein]; Lithium Chloride affects the reaction [Diethylhexyl Phthalate affects the reaction [[Dexamethasone co-treated with Ascorbic Acid co-treated with beta-glycerophosphoric acid] affects the expression of RUNX2 protein]]; Lithium Chloride affects the reaction [mono-(2-ethylhexyl)phthalate affects the reaction [[Dexamethasone co-treated with Ascorbic Acid co-treated with beta-glycerophosphoric acid] affects the expression of RUNX2 protein]]; mono-(2-ethylhexyl)phthalate affects the reaction [[Dexamethasone co-treated with Ascorbic Acid co-treated with beta-glycerophosphoric acid] affects the expression of RUNX2 mRNA]; mono-(2-ethylhexyl)phthalate affects the reaction [[Dexamethasone co-treated with Ascorbic Acid co-treated with beta-glycerophosphoric acid] affects the expression of RUNX2 protein]; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [[Ascorbic Acid co-treated with Dexamethasone co-treated with beta-glycerophosphoric acid] results in increased expression of RUNX2 mRNA]; Particulate Matter inhibits the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid] results in increased expression of RUNX2 mRNA]; Particulate Matter inhibits the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid] results in increased expression of RUNX2 protein]; Rosiglitazone inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of RUNX2 mRNA]; SMAD4 protein inhibits the reaction [Particulate Matter inhibits the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid] results in increased expression of RUNX2 protein]] [Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of RUNX2 protein; [beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] affects the expression of RUNX2 mRNA; Dexamethasone inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of RUNX2 protein]; ginsenoside Rg3 inhibits the reaction [Dexamethasone inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of RUNX2 protein]]; Hydrogen Peroxide affects the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] affects the expression of RUNX2 mRNA]; NOG protein inhibits the reaction [ginsenoside Rg3 inhibits the reaction [Dexamethasone inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of RUNX2 protein]]]; Quercetin affects the reaction [Hydrogen Peroxide affects the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] affects the expression of RUNX2 mRNA]]
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CTD |
PMID:17692823 PMID:22940495 PMID:23111315 PMID:26424790 PMID:26492236 PMID:27028516 PMID:27387537 PMID:28921615 PMID:31935364 PMID:32324263 PMID:32473317 PMID:34562440 PMID:34575692 PMID:35738543 PMID:35780740 PMID:38914176 More...
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|
NCBI chr 9:23,661,278...23,990,248
Ensembl chr 9:23,664,952...23,990,027
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| G
|
Satb2
|
SATB homeobox 2
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multiple interactions
|
ISO
|
[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in increased expression of SATB2 mRNA; EZH2 protein inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in increased expression of SATB2 mRNA]
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CTD |
PMID:26424790 |
|
NCBI chr 9:65,842,351...66,028,569
Ensembl chr 9:65,844,570...66,021,238
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|
| G
|
Scd
|
stearoyl-CoA desaturase
|
multiple interactions
|
ISO
|
[Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of SCD1 mRNA; SRC protein promotes the reaction [Tetrachlorodibenzodioxin inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of SCD1 mRNA]]; Tetrachlorodibenzodioxin inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of SCD1 mRNA]
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CTD |
PMID:14505802 |
|
NCBI chr 1:253,218,968...253,232,101
Ensembl chr 1:253,218,970...253,231,785
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|
| G
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Smad1
|
SMAD family member 1
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multiple interactions
|
ISO
|
[Ascorbic Acid co-treated with Dexamethasone co-treated with beta-glycerophosphoric acid] results in increased expression of SMAD1 mRNA; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [[Ascorbic Acid co-treated with Dexamethasone co-treated with beta-glycerophosphoric acid] results in increased expression of SMAD1 mRNA]
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CTD |
PMID:26492236 |
|
NCBI chr19:45,417,430...45,477,962
Ensembl chr19:45,417,433...45,477,957
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|
| G
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Smad2
|
SMAD family member 2
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multiple interactions
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ISO
|
[beta-glycerophosphoric acid co-treated with Ascorbic Acid] results in decreased phosphorylation of and affects the localization of SMAD2 protein; Particulate Matter promotes the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid] results in decreased phosphorylation of and affects the localization of SMAD2 protein]
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CTD |
PMID:38914176 |
|
NCBI chr18:72,124,792...72,193,345
Ensembl chr18:72,124,863...72,187,388
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|
| G
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Smad4
|
SMAD family member 4
|
multiple interactions
|
ISO
|
[Ascorbic Acid co-treated with Dexamethasone co-treated with beta-glycerophosphoric acid] results in increased expression of SMAD4 mRNA; [beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Particulate Matter] results in decreased expression of SMAD4 protein; [beta-glycerophosphoric acid co-treated with Ascorbic Acid] results in increased expression of SMAD4 protein; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [[Ascorbic Acid co-treated with Dexamethasone co-treated with beta-glycerophosphoric acid] results in increased expression of SMAD4 mRNA]; Particulate Matter inhibits the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid] results in increased expression of SMAD4 protein]; SMAD4 protein inhibits the reaction [Particulate Matter inhibits the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid] results in increased expression of BGLAP mRNA]]; SMAD4 protein inhibits the reaction [Particulate Matter inhibits the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid] results in increased expression of RUNX2 protein]]; SMAD4 protein promotes the reaction [Particulate Matter inhibits the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid] results in increased expression of SP7 protein]]
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CTD |
PMID:26492236 PMID:38914176 |
|
NCBI chr18:69,518,988...69,549,684
Ensembl chr18:69,518,988...69,549,684
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|
| G
|
Smad5
|
SMAD family member 5
|
multiple interactions
|
ISO
|
[Ascorbic Acid co-treated with Dexamethasone co-treated with beta-glycerophosphoric acid] results in increased expression of SMAD5 mRNA; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [[Ascorbic Acid co-treated with Dexamethasone co-treated with beta-glycerophosphoric acid] results in increased expression of SMAD5 mRNA]
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CTD |
PMID:26492236 |
|
NCBI chr17:7,867,640...7,896,983
Ensembl chr17:7,871,984...7,890,992
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| G
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Smad9
|
SMAD family member 9
|
multiple interactions
|
ISO
|
[Ascorbic Acid co-treated with Dexamethasone co-treated with beta-glycerophosphoric acid] results in increased expression of SMAD9 mRNA; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [[Ascorbic Acid co-treated with Dexamethasone co-treated with beta-glycerophosphoric acid] results in increased expression of SMAD9 mRNA]
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CTD |
PMID:26492236 |
|
NCBI chr 2:141,106,668...141,156,477
Ensembl chr 2:141,106,668...141,156,477
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|
| G
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Smurf1
|
SMAD specific E3 ubiquitin protein ligase 1
|
multiple interactions
|
ISO
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[Particulate Matter co-treated with beta-glycerophosphoric acid co-treated with Ascorbic Acid] results in increased expression of SMURF1 mRNA
|
CTD |
PMID:38914176 |
|
NCBI chr12:14,748,717...14,840,273
Ensembl chr12:14,749,043...14,840,273
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|
| G
|
Sox2
|
SRY-box transcription factor 2
|
multiple interactions
|
ISO
|
[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in decreased expression of SOX2 mRNA
|
CTD |
PMID:28189605 |
|
NCBI chr 2:119,465,131...119,467,542
Ensembl chr 2:119,454,541...119,496,350
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|
| G
|
Sox9
|
SRY-box transcription factor 9
|
multiple interactions
|
ISO
|
[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in decreased expression of SOX9 mRNA
|
CTD |
PMID:26424790 |
|
NCBI chr10:98,305,744...98,311,250
Ensembl chr10:98,305,744...98,311,250
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|
| G
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Sp7
|
Sp7 transcription factor
|
multiple interactions increases expression
|
ISO
|
[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SP7 mRNA; [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS1 protein co-treated with Firemaster 550] results in decreased expression of SP7 mRNA; [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS1 protein co-treated with triphenyl phosphate] results in decreased expression of SP7 mRNA; [Ascorbic Acid co-treated with Dexamethasone co-treated with beta-glycerophosphoric acid] results in increased expression of SP7 mRNA; [Ascorbic Acid co-treated with Dexamethasone co-treated with beta-glycerophosphoric acid] results in increased expression of SP7 protein; [beta-glycerophosphoric acid co-treated with Ascorbic Acid] results in increased expression of SP7 mRNA; [beta-glycerophosphoric acid co-treated with Ascorbic Acid] results in increased expression of SP7 protein; [Folic Acid co-treated with Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of SP7 mRNA; [Folic Acid co-treated with Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of SP7 protein; Allethrins inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SP7 mRNA]; d,d-T80-prallethrin inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SP7 mRNA]; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [[Ascorbic Acid co-treated with Dexamethasone co-treated with beta-glycerophosphoric acid] results in increased expression of SP7 mRNA]; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [[Ascorbic Acid co-treated with Dexamethasone co-treated with beta-glycerophosphoric acid] results in increased expression of SP7 protein]; Particulate Matter inhibits the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid] results in increased expression of SP7 mRNA]; Particulate Matter inhibits the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid] results in increased expression of SP7 protein]; Pioglitazone inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SP7 mRNA]; quinoxyfen inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SP7 mRNA]; Rosiglitazone inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SP7 mRNA]; SMAD4 protein promotes the reaction [Particulate Matter inhibits the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid] results in increased expression of SP7 protein]]; tetrabromobisphenol A inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SP7 mRNA]; Tretinoin inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SP7 mRNA]; triphenyltin hydroxide inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SP7 mRNA] beta-glycerophosphoric acid results in increased expression of SP7 protein [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SP7 mRNA; [Dexamethasone co-treated with ascorbate-2-phosphate co-treated with beta-glycerophosphoric acid co-treated with Cholecalciferol] results in increased expression of SP7 mRNA; [Dexamethasone co-treated with ascorbate-2-phosphate co-treated with beta-glycerophosphoric acid] results in increased expression of SP7 mRNA; Bexarotene inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SP7 mRNA]; bisphenol A inhibits the reaction [beta-glycerophosphoric acid results in increased expression of SP7 protein]; cordycepin inhibits the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [[Dexamethasone co-treated with ascorbate-2-phosphate co-treated with beta-glycerophosphoric acid] results in increased expression of SP7 mRNA]]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Dexamethasone co-treated with ascorbate-2-phosphate co-treated with beta-glycerophosphoric acid] results in increased expression of SP7 mRNA]; Rosiglitazone inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SP7 mRNA]; tributyltin inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SP7 mRNA]
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CTD |
PMID:22940495 PMID:25062436 PMID:25932594 PMID:26492236 PMID:32324263 PMID:32473317 PMID:34575692 PMID:35780740 PMID:38914176 More...
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|
NCBI chr 7:135,363,193...135,373,376
Ensembl chr 7:135,363,199...135,373,559
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| G
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Sparc
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secreted protein acidic and cysteine rich
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multiple interactions
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ISO
|
[Cholecalciferol co-treated with beta-glycerophosphoric acid co-treated with Ascorbic Acid] results in increased expression of SPARC protein
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CTD |
PMID:17692823 |
|
NCBI chr10:40,017,065...40,038,816
Ensembl chr10:40,017,075...40,039,268
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|
| G
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Spp1
|
secreted phosphoprotein 1
|
multiple interactions
|
ISO
|
[Cholecalciferol co-treated with beta-glycerophosphoric acid co-treated with Ascorbic Acid] results in increased expression of SPP1 protein; [Dexamethasone co-treated with ascorbate-2-phosphate co-treated with beta-glycerophosphoric acid co-treated with Cholecalciferol] results in increased expression of SPP1 mRNA; PARG mRNA inhibits the reaction [[Dexamethasone co-treated with ascorbate-2-phosphate co-treated with beta-glycerophosphoric acid co-treated with Cholecalciferol] results in increased expression of SPP1 mRNA] [Ascorbic Acid co-treated with Dexamethasone co-treated with beta-glycerophosphoric acid] results in increased expression of SPP1 mRNA; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [[Ascorbic Acid co-treated with Dexamethasone co-treated with beta-glycerophosphoric acid] results in increased expression of SPP1 mRNA]
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CTD |
PMID:17692823 PMID:22940495 PMID:26492236 |
|
NCBI chr14:5,613,569...5,620,695
Ensembl chr14:5,613,576...5,619,820
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|
| G
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Sqstm1
|
sequestosome 1
|
multiple interactions
|
ISO
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[Dexamethasone co-treated with ascorbate-2-phosphate co-treated with beta-glycerophosphoric acid] affects the expression of SQSTM1 protein
|
CTD |
PMID:23111315 |
|
NCBI chr10:35,026,598...35,037,750
Ensembl chr10:35,026,598...35,037,750
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|
| G
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Src
|
SRC proto-oncogene, non-receptor tyrosine kinase
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multiple interactions
|
ISO
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SRC protein promotes the reaction [Tetrachlorodibenzodioxin inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of PPARG mRNA]]; SRC protein promotes the reaction [Tetrachlorodibenzodioxin inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of SCD1 mRNA]]
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CTD |
PMID:14505802 |
|
NCBI chr 3:166,511,616...166,559,463
Ensembl chr 3:166,511,985...166,559,462
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|
| G
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Srebf1
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sterol regulatory element binding transcription factor 1
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multiple interactions
|
ISO
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[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SREBF1 mRNA; bexarotene promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SREBF1 mRNA]; rosiglitazone promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SREBF1 mRNA]; tributyltin promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SREBF1 mRNA]
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CTD |
PMID:25932594 |
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NCBI chr10:45,507,152...45,529,164
Ensembl chr10:45,507,152...45,529,164
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| G
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Stc1
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stanniocalcin 1
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decreases expression
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EXP
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beta-glycerophosphoric acid results in decreased expression of STC1 mRNA
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CTD |
PMID:17438129 |
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NCBI chr15:50,709,439...50,720,093
Ensembl chr15:50,709,415...50,720,082
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| G
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Suv39h1
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SUV39H1 histone lysine methyltransferase
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multiple interactions
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ISO
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[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in decreased expression of SUV39H1 mRNA
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CTD |
PMID:26424790 |
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NCBI chr X:17,093,059...17,105,942
Ensembl chr X:17,092,986...17,105,942
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| G
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Suv39h1-ps1
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SUV39H1 histone lysine methyltransferase, pseudogene 1
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multiple interactions
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ISO
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[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in decreased expression of SUV39H1 mRNA
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CTD |
PMID:26424790 |
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NCBI chr X:146,828,818...146,831,485
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| G
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Suv39h2
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SUV39H2 histone lysine methyltransferase
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multiple interactions
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ISO
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[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in decreased expression of SUV39H2 mRNA
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CTD |
PMID:26424790 |
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NCBI chr17:79,665,467...79,684,492
Ensembl chr17:79,665,376...79,684,492
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| G
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Tafazzin
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tafazzin, phospholipid-lysophospholipid transacylase
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multiple interactions
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ISO
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[Cholecalciferol co-treated with beta-glycerophosphoric acid co-treated with Ascorbic Acid] results in increased expression of TAFAZZIN mRNA
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CTD |
PMID:17692823 |
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NCBI chr X:157,216,826...157,230,524
Ensembl chr X:157,216,554...157,225,287
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| G
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Tcf19
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transcription factor 19
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multiple interactions
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ISO
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[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in decreased expression of TCF19 mRNA
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CTD |
PMID:26424790 |
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NCBI chr20:3,223,464...3,227,569
Ensembl chr20:3,223,324...3,230,060
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| G
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Tcf20
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transcription factor 20
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multiple interactions
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ISO
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[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in increased expression of TCF20 mRNA
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CTD |
PMID:26424790 |
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NCBI chr 7:115,833,523...116,009,790
Ensembl chr 7:115,834,416...115,931,915
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| G
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Tnfrsf11b
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TNF receptor superfamily member 11B
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multiple interactions
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ISO
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[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in increased expression of TNFRSF11B mRNA; EZH2 protein inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in increased expression of TNFRSF11B mRNA]
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CTD |
PMID:26424790 |
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NCBI chr 7:87,456,318...87,484,324
Ensembl chr 7:87,456,319...87,485,075
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| G
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Tnfsf11
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TNF superfamily member 11
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multiple interactions
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ISO
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[Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of and results in increased secretion of TNFSF11 protein
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CTD |
PMID:32156525 |
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NCBI chr15:60,083,008...60,114,479
Ensembl chr15:60,083,008...60,114,479
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| G
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Uhrf1
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ubiquitin-like with PHD and ring finger domains 1
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multiple interactions
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ISO
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[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in decreased expression of UHRF1 mRNA
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CTD |
PMID:26424790 |
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NCBI chr 9:1,220,162...1,241,792
Ensembl chr 9:1,222,063...1,241,792
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| G
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Uhrf2
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ubiquitin like with PHD and ring finger domains 2
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multiple interactions
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ISO
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[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in increased expression of UHRF2 mRNA
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CTD |
PMID:26424790 |
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NCBI chr 1:237,224,050...237,291,406
Ensembl chr 1:237,228,456...237,292,353
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| G
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Vcl
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vinculin
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multiple interactions
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ISO
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[Dexamethasone co-treated with beta-glycerophosphoric acid] results in increased expression of VCL protein; Hydroxychloroquine inhibits the reaction [[Dexamethasone co-treated with beta-glycerophosphoric acid] results in increased expression of VCL protein]
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CTD |
PMID:28975700 |
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NCBI chr15:3,315,069...3,404,891
Ensembl chr15:3,315,069...3,405,163
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| G
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Wnt1
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Wnt family member 1
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multiple interactions
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ISO
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[Dexamethasone co-treated with beta-glycerophosphoric acid co-treated with ascorbate-2-phosphate] results in increased expression of WNT1 mRNA; lead nitrate inhibits the reaction [[Dexamethasone co-treated with beta-glycerophosphoric acid co-treated with ascorbate-2-phosphate] results in increased expression of WNT1 mRNA] [Dexamethasone co-treated with Ascorbic Acid co-treated with beta-glycerophosphoric acid] affects the expression of WNT1 mRNA; [Dexamethasone co-treated with Ascorbic Acid co-treated with beta-glycerophosphoric acid] affects the expression of WNT1 protein; Diethylhexyl Phthalate affects the reaction [[Dexamethasone co-treated with Ascorbic Acid co-treated with beta-glycerophosphoric acid] affects the expression of WNT1 mRNA]; Diethylhexyl Phthalate affects the reaction [[Dexamethasone co-treated with Ascorbic Acid co-treated with beta-glycerophosphoric acid] affects the expression of WNT1 protein]; mono-(2-ethylhexyl)phthalate affects the reaction [[Dexamethasone co-treated with Ascorbic Acid co-treated with beta-glycerophosphoric acid] affects the expression of WNT1 mRNA]; mono-(2-ethylhexyl)phthalate affects the reaction [[Dexamethasone co-treated with Ascorbic Acid co-treated with beta-glycerophosphoric acid] affects the expression of WNT1 protein]
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CTD |
PMID:28921615 PMID:35738543 |
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NCBI chr 7:131,817,558...131,821,605
Ensembl chr 7:131,817,558...131,821,605
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| G
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Wnt11
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Wnt family member 11
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multiple interactions
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ISO
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[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in increased expression of WNT11 mRNA; cadmium sulfate inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in increased expression of WNT11 mRNA]
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CTD |
PMID:28189605 |
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NCBI chr 1:162,545,660...162,565,456
Ensembl chr 1:162,545,680...162,564,660
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|
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| G
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Cyp1a1
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cytochrome P450, family 1, subfamily a, polypeptide 1
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decreases activity
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ISO
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Isosorbide Dinitrate results in decreased activity of CYP1A1 protein
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CTD |
PMID:33814510 |
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NCBI chr 8:66,991,940...66,998,014
Ensembl chr 8:66,991,970...66,998,012
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| G
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Edn1
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endothelin 1
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multiple interactions
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ISO
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[Isosorbide Dinitrate co-treated with Plant Preparations] results in decreased expression of EDN1 mRNA
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CTD |
PMID:15719745 |
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NCBI chr17:22,660,799...22,666,687
Ensembl chr17:22,660,799...22,666,687
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| G
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G6pd
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glucose-6-phosphate dehydrogenase
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decreases response to substance
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ISO
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G6PD protein results in decreased susceptibility to Isosorbide Dinitrate
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CTD |
PMID:6401899 |
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NCBI chr X:157,352,364...157,372,144
Ensembl chr X:157,352,373...157,372,144
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| G
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Nos3
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nitric oxide synthase 3
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multiple interactions
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ISO
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[Isosorbide Dinitrate co-treated with Ascorbic Acid] affects the expression of NOS3 mRNA; [Isosorbide Dinitrate co-treated with Plant Preparations] results in increased expression of NOS3 mRNA
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CTD |
PMID:15719745 |
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NCBI chr 4:11,686,088...11,706,604
Ensembl chr 4:11,686,268...11,706,664
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| G
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Pafah1b1
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platelet-activating factor acetylhydrolase 1b, regulatory subunit 1
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multiple interactions
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EXP
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isosorbide-5-mononitrate inhibits the reaction [Castor Oil results in increased expression of PAFAH1B1 protein]
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CTD |
PMID:8738301 |
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NCBI chr10:60,031,441...60,090,259
Ensembl chr10:60,032,514...60,090,196
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| G
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Ddr1
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discoidin domain receptor tyrosine kinase 1
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ISO
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lysophosphatidic acid increased expression of Ddr1 in 3T3 and GD25 cells
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RGD |
PMID:28199848 |
RGD:151347403 |
NCBI chr20:3,047,269...3,069,277
Ensembl chr20:3,050,375...3,069,276
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| G
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Prkd1
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protein kinase D1
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increases phosphorylation
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EXP
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LPA increases phosphorylation of Prkd1 protein in neonatal ventricular myocytes
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RGD |
PMID:16648482 |
RGD:243065275 |
NCBI chr 6:73,460,640...73,774,433
Ensembl chr 6:73,460,640...73,836,509
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