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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:manganese(II) chloride
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Accession:CHEBI:63041 term browser browse the term
Definition:An inorganic chloride in which manganese(II) is coordinated to two chloride ions. In its anhydrous state manganese(II) chloride is a polymeric solid, which adopts a layered cadmium chloride-like structure.
Synonyms:exact_synonym: manganese(2+) dichloride
 related_synonym: Formula=Cl2Mn;   InChI=1S/2ClH.Mn/h2*1H;/q;;+2/p-2;   InChIKey=GLFNIEUTAYBVOC-UHFFFAOYSA-L;   Mangandichlorid;   Manganese bichloride;   Manganese(II) chloride (1:2);   Manganous chloride;   SMILES=Cl[Mn]Cl;   dichlorure de manganese;   manganese(II) dichloride;   manganous dichloride
 xref: CAS:7773-01-5
 xref_mesh: MESH:C025340
 xref: MetaCyc:CPD0-2394;   PMID:101555;   PMID:146543;   PMID:19801673;   PMID:3143594;   PMID:4476198;   PMID:4771199;   PMID:98204;   Reaxys:8128170;   Wikipedia:Manganese(II)_chloride



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manganese(II) chloride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G 1700037C18Rik RIKEN cDNA 1700037C18 gene increases expression ISO manganese chloride results in increased expression of C10H16ORF90 mRNA CTD PMID:28801915 NCBI chr16:3,723,662...3,726,553
Ensembl chr16:3,713,043...3,726,553
JBrowse link
G 2900026A02Rik RIKEN cDNA 2900026A02 gene increases expression ISO manganese chloride results in increased expression of KIAA1671 mRNA CTD PMID:28801915 NCBI chr 5:113,234,189...113,369,158
Ensembl chr 5:113,234,189...113,369,102
JBrowse link
G Abca5 ATP-binding cassette, sub-family A member 5 decreases expression ISO manganese chloride results in decreased expression of ABCA5 mRNA CTD PMID:17175027 NCBI chr11:110,160,195...110,228,542
Ensembl chr11:110,160,195...110,228,542
JBrowse link
G Abca9 ATP-binding cassette, sub-family A member 9 increases expression ISO manganese chloride results in increased expression of ABCA9 mRNA CTD PMID:17175027 NCBI chr11:109,990,919...110,059,532
Ensembl chr11:109,991,575...110,059,022
JBrowse link
G Abcb1a ATP-binding cassette, sub-family B member 1A increases expression ISO manganese chloride results in increased expression of ABCB1A mRNA CTD PMID:26745496 NCBI chr 5:8,617,091...8,798,575
Ensembl chr 5:8,710,077...8,798,575
JBrowse link
G Abcb1b ATP-binding cassette, sub-family B member 1B increases expression ISO manganese chloride results in increased expression of ABCB1B mRNA CTD PMID:28801915 NCBI chr 5:8,848,147...8,916,314
Ensembl chr 5:8,848,147...8,916,315
JBrowse link
G Abcc2 ATP-binding cassette, sub-family member 2 increases expression
decreases methylation
ISO manganese chloride results in increased expression of ABCC2 mRNA
manganese chloride results in decreased methylation of ABCC2 gene
CTD PMID:28801915 NCBI chr19:43,770,747...43,826,771
Ensembl chr19:43,770,631...43,829,179
JBrowse link
G Abcc8 ATP-binding cassette, sub-family C member 8 multiple interactions ISO [manganese chloride results in increased abundance of Manganese] which results in increased expression of ABCC8 protein CTD PMID:32659473 NCBI chr 7:45,753,952...45,829,441
Ensembl chr 7:45,753,947...45,829,457
JBrowse link
G Abi2 abl interactor 2 increases expression ISO manganese chloride results in increased expression of ABI2 mRNA CTD PMID:17175027 NCBI chr 1:60,444,927...60,521,104
Ensembl chr 1:60,448,778...60,520,317
JBrowse link
G Abitram actin binding transcription modulator increases expression ISO manganese chloride results in increased expression of ABITRAM mRNA CTD PMID:28801915 NCBI chr 4:56,802,329...56,809,605
Ensembl chr 4:56,802,345...56,809,601
JBrowse link
G Acap1 ArfGAP with coiled-coil, ankyrin repeat and PH domains 1 increases expression ISO manganese chloride results in increased expression of ACAP1 mRNA CTD PMID:28801915 NCBI chr11:69,772,393...69,786,390
Ensembl chr11:69,772,393...69,786,365
JBrowse link
G Ace angiotensin I converting enzyme increases expression ISO manganese chloride results in increased expression of ACE mRNA CTD PMID:28801915 NCBI chr11:105,858,774...105,880,790
Ensembl chr11:105,858,771...105,880,790
JBrowse link
G Ache acetylcholinesterase increases activity
increases expression
multiple interactions
decreases activity
ISO
EXP
manganese chloride results in increased activity of ACHE protein
manganese chloride results in increased expression of ACHE mRNA
[manganese chloride results in increased abundance of Manganese] promotes the reaction [Ethanol results in increased activity of ACHE protein]; [manganese chloride results in increased abundance of Manganese] which results in increased activity of ACHE protein; Ethanol promotes the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased activity of ACHE protein]; Lycopene inhibits the reaction [manganese chloride results in increased activity of ACHE protein]; Silymarin inhibits the reaction [manganese chloride results in decreased activity of ACHE protein]; Silymarin inhibits the reaction [manganese chloride results in increased activity of ACHE protein]; Silymarin inhibits the reaction [manganese chloride results in increased expression of ACHE mRNA]
[manganese chloride results in increased abundance of Manganese] which results in decreased activity of ACHE protein; [manganese chloride results in increased abundance of Manganese] which results in increased activity of ACHE protein; [manganese chloride results in increased abundance of Manganese] which results in increased expression of ACHE mRNA alternative form
CTD PMID:20503066 PMID:22033861 PMID:22154916 PMID:22192907 PMID:30738988 More... NCBI chr 5:137,286,516...137,292,728
Ensembl chr 5:137,285,781...137,292,728
JBrowse link
G Aco1 aconitase 1 increases activity ISO manganese chloride results in increased activity of ACO1 protein CTD PMID:15893546 PMID:16545456 PMID:16568477 NCBI chr 4:40,143,429...40,199,011
Ensembl chr 4:40,143,081...40,198,338
JBrowse link
G Aco2 aconitase 2, mitochondrial multiple interactions
decreases expression
decreases activity
ISO ferric ammonium citrate inhibits the reaction [manganese chloride results in decreased activity of ACO2 protein]
manganese chloride results in decreased expression of ACO2 mRNA; manganese chloride results in decreased expression of ACO2 protein
Iron inhibits the reaction [manganese chloride results in decreased activity of ACO2 protein]
CTD PMID:9675333 PMID:16625280 NCBI chr15:81,756,664...81,799,338
Ensembl chr15:81,756,510...81,799,334
JBrowse link
G Acot2 acyl-CoA thioesterase 2 increases expression ISO manganese chloride results in increased expression of ACOT2 mRNA CTD PMID:28801915 NCBI chr12:84,034,635...84,040,651
Ensembl chr12:84,034,635...84,040,647
JBrowse link
G Acp5 acid phosphatase 5, tartrate resistant increases expression
increases methylation
ISO manganese chloride results in increased expression of ACP5 mRNA
manganese chloride results in increased methylation of ACP5 gene
CTD PMID:22281203 PMID:28801915 NCBI chr 9:22,038,023...22,047,042
Ensembl chr 9:22,038,023...22,047,007
JBrowse link
G Acr acrosin prepropeptide increases expression ISO manganese chloride results in increased expression of ACR mRNA CTD PMID:28801915 NCBI chr15:89,452,549...89,458,790
Ensembl chr15:89,452,529...89,458,788
JBrowse link
G Acsl3 acyl-CoA synthetase long-chain family member 3 decreases expression EXP manganese chloride results in decreased expression of ACSL3 mRNA CTD PMID:15295902 NCBI chr 1:78,635,600...78,685,462
Ensembl chr 1:78,635,542...78,685,460
JBrowse link
G Acss2 acyl-CoA synthetase short-chain family member 2 decreases expression ISO manganese chloride results in decreased expression of ACSS2 mRNA CTD PMID:28801915 NCBI chr 2:155,359,963...155,404,663
Ensembl chr 2:155,359,868...155,427,644
JBrowse link
G Acta1 actin alpha 1, skeletal muscle decreases expression ISO manganese chloride results in decreased expression of ACTA1 mRNA CTD PMID:26745496 NCBI chr 8:124,618,497...124,621,514
Ensembl chr 8:124,618,508...124,621,490
JBrowse link
G Acta2 actin alpha 2, smooth muscle, aorta increases expression ISO manganese chloride results in increased expression of ACTA2 mRNA CTD PMID:28801915 NCBI chr19:34,217,736...34,232,985
Ensembl chr19:34,218,490...34,232,990
JBrowse link
G Actb actin, beta decreases expression
increases expression
ISO manganese chloride results in decreased expression of ACTB protein
manganese chloride results in increased expression of ACTB mRNA
CTD PMID:20452446 NCBI chr 5:142,888,870...142,892,509
Ensembl chr 5:142,888,870...142,892,509
JBrowse link
G Acvrl1 activin A receptor, type II-like 1 increases expression ISO manganese chloride results in increased expression of ACVRL1 mRNA CTD PMID:28801915 NCBI chr15:101,026,403...101,043,217
Ensembl chr15:101,026,403...101,043,217
JBrowse link
G Adam19 ADAM metallopeptidase domain 19 increases expression ISO manganese chloride results in increased expression of ADAM19 mRNA CTD PMID:28801915 NCBI chr11:45,945,329...46,038,174
Ensembl chr11:45,946,819...46,038,170
JBrowse link
G Adamts1 ADAM metallopeptidase with thrombospondin type 1 motif 1 decreases expression ISO manganese chloride results in decreased expression of ADAMTS1 mRNA CTD PMID:28801915 NCBI chr16:85,590,715...85,600,001
Ensembl chr16:85,590,715...85,600,001
JBrowse link
G Adamts5 ADAM metallopeptidase with thrombospondin type 1 motif 5 decreases expression ISO manganese chloride results in decreased expression of ADAMTS5 mRNA CTD PMID:28801915 NCBI chr16:85,655,045...85,698,013
Ensembl chr16:85,653,061...85,698,716
JBrowse link
G Adcy6 adenylate cyclase 6 increases expression ISO manganese chloride results in increased expression of ADCY6 mRNA CTD PMID:28801915 NCBI chr15:98,484,982...98,508,119
Ensembl chr15:98,487,854...98,507,957
JBrowse link
G Add2 adducin 2 increases expression ISO manganese chloride results in increased expression of ADD2 mRNA CTD PMID:28801915 NCBI chr 6:86,005,663...86,101,391
Ensembl chr 6:86,005,663...86,101,391
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing increases expression ISO manganese chloride results in increased expression of ADIPOQ mRNA CTD PMID:28801915 NCBI chr16:22,965,286...22,976,718
Ensembl chr16:22,965,286...22,976,778
JBrowse link
G Adm adrenomedullin increases expression
decreases expression
ISO manganese chloride results in increased expression of ADM mRNA
manganese chloride results in decreased expression of ADM mRNA
CTD PMID:17175027 PMID:28801915 NCBI chr 7:110,226,864...110,229,027
Ensembl chr 7:110,226,868...110,229,027
JBrowse link
G Adora2a adenosine A2a receptor increases expression ISO manganese chloride results in increased expression of ADORA2A mRNA CTD PMID:28801915 NCBI chr10:75,152,711...75,170,626
Ensembl chr10:75,152,711...75,170,618
JBrowse link
G Aen apoptosis enhancing nuclease increases expression ISO manganese chloride results in increased expression of AEN mRNA CTD PMID:28801915 NCBI chr 7:78,545,675...78,560,957
Ensembl chr 7:78,545,602...78,560,957
JBrowse link
G Aff1 AF4/FMR2 family, member 1 increases expression ISO manganese chloride results in increased expression of AFF1 mRNA CTD PMID:28801915 NCBI chr 5:103,840,307...104,003,188
Ensembl chr 5:103,840,240...104,003,188
JBrowse link
G Afmid arylformamidase increases expression ISO manganese chloride results in increased expression of AFMID mRNA CTD PMID:28801915 NCBI chr11:117,716,329...117,730,734
Ensembl chr11:117,716,750...117,730,734
JBrowse link
G Afp alpha fetoprotein decreases expression ISO manganese chloride results in decreased expression of AFP mRNA CTD PMID:26745496 NCBI chr 5:90,638,573...90,656,766
Ensembl chr 5:90,638,596...90,656,766
JBrowse link
G Ahnak2 AHNAK nucleoprotein 2 increases expression ISO manganese chloride results in increased expression of AHNAK2 mRNA CTD PMID:28801915 NCBI chr12:112,738,631...112,766,278
Ensembl chr12:112,738,628...112,766,277
JBrowse link
G Aicda activation-induced cytidine deaminase increases expression ISO manganese chloride results in increased expression of AICDA mRNA CTD PMID:28801915 NCBI chr 6:122,530,768...122,541,139
Ensembl chr 6:122,530,760...122,541,139
JBrowse link
G Aif1 allograft inflammatory factor 1 increases expression EXP manganese chloride results in increased expression of AIF1 protein CTD PMID:28595911 NCBI chr17:35,389,967...35,394,977
Ensembl chr17:35,389,967...35,395,044
JBrowse link
G Akap7 A kinase anchor protein 7 decreases expression ISO manganese chloride results in decreased expression of AKAP7 mRNA CTD PMID:17175027 NCBI chr10:25,044,988...25,175,115
Ensembl chr10:25,044,988...25,183,768
JBrowse link
G Akr1b1 aldo-keto reductase family 1 member B increases expression ISO manganese chloride results in increased expression of AKR1B1 mRNA CTD PMID:22281203 NCBI chr 6:34,280,865...34,294,424
Ensembl chr 6:34,279,369...34,294,413
JBrowse link
G Akt1 thymoma viral proto-oncogene 1 decreases phosphorylation
multiple interactions
ISO
EXP
manganese chloride results in decreased phosphorylation of AKT1 protein
[manganese chloride results in increased abundance of Manganese] which results in decreased phosphorylation of AKT1 protein; benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in decreased phosphorylation of AKT1 protein]
NTF3 protein inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in decreased phosphorylation of AKT1 protein]
CTD PMID:30040983 PMID:31676349 NCBI chr12:112,620,260...112,641,266
Ensembl chr12:112,620,255...112,641,318
JBrowse link
G Alb albumin multiple interactions ISO [sodium arsenite co-treated with Cadmium Chloride co-treated with lead acetate co-treated with Mercuric Chloride co-treated with chromium trioxide co-treated with nickel chloride co-treated with manganese chloride co-treated with ferric chloride] results in decreased expression of ALB protein CTD PMID:17657459 NCBI chr 5:90,608,729...90,624,461
Ensembl chr 5:90,608,756...90,624,461
JBrowse link
G Aldh18a1 aldehyde dehydrogenase 18 family, member A1 increases expression ISO manganese chloride results in increased expression of ALDH18A1 mRNA CTD PMID:28801915 NCBI chr19:40,538,701...40,576,907
Ensembl chr19:40,538,701...40,576,907
JBrowse link
G Aldh1a1 aldehyde dehydrogenase family 1, subfamily A1 decreases expression ISO manganese chloride results in decreased expression of ALDH1A1 mRNA CTD PMID:28801915 NCBI chr19:20,469,947...20,620,827
Ensembl chr19:20,470,079...20,620,829
JBrowse link
G Aldh4a1 aldehyde dehydrogenase 4 family, member A1 increases expression ISO manganese chloride results in increased expression of ALDH4A1 mRNA CTD PMID:28801915 NCBI chr 4:139,348,404...139,377,002
Ensembl chr 4:139,350,177...139,377,001
JBrowse link
G Aldoc aldolase C, fructose-bisphosphate decreases expression ISO manganese chloride results in decreased expression of ALDOC mRNA CTD PMID:28801915 NCBI chr11:78,213,899...78,218,607
Ensembl chr11:78,213,794...78,218,607
JBrowse link
G Alkal1 ALK and LTK ligand 1 increases expression ISO manganese chloride results in increased expression of ALKAL1 mRNA CTD PMID:28801915 NCBI chr 1:6,429,555...6,464,955
Ensembl chr 1:6,429,442...6,464,955
JBrowse link
G Amigo3 adhesion molecule with Ig like domain 3 increases expression ISO manganese chloride results in increased expression of AMIGO3 mRNA CTD PMID:28801915 NCBI chr 9:107,930,358...107,932,900
Ensembl chr 9:107,930,358...107,932,900
JBrowse link
G Angpt2 angiopoietin 2 decreases expression ISO manganese chloride results in decreased expression of ANGPT2 mRNA CTD PMID:26745496 NCBI chr 8:18,740,279...18,791,578
Ensembl chr 8:18,740,279...18,791,578
JBrowse link
G Angptl4 angiopoietin-like 4 increases expression ISO manganese chloride results in increased expression of ANGPTL4 mRNA CTD PMID:17175027 NCBI chr17:33,993,874...34,000,549
Ensembl chr17:33,992,724...34,000,804
JBrowse link
G Ankrd28 ankyrin repeat domain 28 increases expression ISO manganese chloride results in increased expression of ANKRD28 mRNA CTD PMID:28801915 NCBI chr14:31,418,687...31,552,374
Ensembl chr14:31,420,725...31,552,608
JBrowse link
G Ano3 anoctamin 3 increases expression ISO manganese chloride results in increased expression of ANO3 mRNA CTD PMID:28801915 NCBI chr 2:110,485,546...110,780,854
Ensembl chr 2:110,485,546...110,781,268
JBrowse link
G Anp32a acidic nuclear phosphoprotein 32 family member A multiple interactions EXP [manganese chloride results in increased abundance of Manganese] which results in decreased expression of ANP32A mRNA CTD PMID:35690225 NCBI chr 9:62,248,637...62,286,084
Ensembl chr 9:62,248,575...62,286,094
JBrowse link
G Anxa3 annexin A3 decreases expression ISO manganese chloride results in decreased expression of ANXA3 mRNA CTD PMID:28801915 NCBI chr 5:96,941,257...96,993,825
Ensembl chr 5:96,941,198...96,993,825
JBrowse link
G Aopep aminopeptidase O decreases expression ISO manganese chloride results in decreased expression of AOPEP mRNA CTD PMID:28801915 NCBI chr13:63,112,707...63,473,910
Ensembl chr13:63,112,707...63,473,910
JBrowse link
G Ap3b2 adaptor-related protein complex 3, beta 2 subunit increases expression ISO manganese chloride results in increased expression of AP3B2 mRNA CTD PMID:17175027 NCBI chr 7:81,110,147...81,143,722
Ensembl chr 7:81,110,147...81,143,673
JBrowse link
G Apbb3 amyloid beta precursor protein binding family B member 3 increases expression ISO manganese chloride results in increased expression of APBB3 mRNA CTD PMID:28801915 NCBI chr18:36,804,207...36,812,419
Ensembl chr18:36,804,207...36,812,419
JBrowse link
G Apc APC, WNT signaling pathway regulator increases methylation
decreases expression
ISO manganese chloride results in increased methylation of APC gene
manganese chloride results in decreased expression of APC mRNA
CTD PMID:27913844 NCBI chr18:34,353,350...34,455,243
Ensembl chr18:34,353,977...34,455,605
JBrowse link
G Apoa2 apolipoprotein A-II decreases expression ISO manganese chloride results in decreased expression of APOA2 mRNA CTD PMID:28801915 NCBI chr 1:171,049,133...171,053,948
Ensembl chr 1:171,052,623...171,053,948
JBrowse link
G Apold1 apolipoprotein L domain containing 1 increases expression ISO manganese chloride results in increased expression of APOLD1 mRNA CTD PMID:28801915 NCBI chr 6:134,958,964...134,963,799
Ensembl chr 6:134,958,681...134,963,799
JBrowse link
G Aqp3 aquaporin 3 decreases expression ISO manganese chloride results in decreased expression of AQP3 mRNA CTD PMID:28801915 NCBI chr 4:41,092,724...41,098,183
Ensembl chr 4:41,092,722...41,098,183
JBrowse link
G Areg amphiregulin increases expression ISO manganese chloride results in increased expression of AREG mRNA CTD PMID:28801915 NCBI chr 5:91,287,458...91,296,291
Ensembl chr 5:91,287,458...91,296,291
JBrowse link
G Arg1 arginase, liver increases methylation
increases expression
multiple interactions
ISO
EXP
manganese chloride results in increased methylation of ARG1 gene
manganese chloride results in increased expression of ARG1 mRNA
[manganese chloride results in increased abundance of Manganese] which results in increased expression of ARG1 mRNA
CTD PMID:28801915 PMID:34018660 NCBI chr10:24,791,105...24,803,368
Ensembl chr10:24,791,119...24,803,382
JBrowse link
G Arhgap24 Rho GTPase activating protein 24 decreases expression ISO manganese chloride results in decreased expression of ARHGAP24 mRNA CTD PMID:28801915 NCBI chr 5:102,355,043...103,053,743
Ensembl chr 5:102,629,257...103,045,803
JBrowse link
G Arhgdia Rho GDP dissociation inhibitor alpha decreases expression ISO manganese chloride results in decreased expression of ARHGDIA mRNA CTD PMID:17175027 NCBI chr11:120,468,925...120,472,450
Ensembl chr11:120,468,930...120,472,450
JBrowse link
G Arhgef10 Rho guanine nucleotide exchange factor 10 increases expression ISO manganese chloride results in increased expression of ARHGEF10 mRNA CTD PMID:28801915 NCBI chr 8:14,956,405...15,051,085
Ensembl chr 8:14,961,663...15,051,085
JBrowse link
G Arhgef16 Rho guanine nucleotide exchange factor 16 increases expression ISO manganese chloride results in increased expression of ARHGEF16 mRNA CTD PMID:28801915 NCBI chr 4:154,362,926...154,384,535
Ensembl chr 4:154,362,943...154,386,133
JBrowse link
G Arhgef4 Rho guanine nucleotide exchange factor 4 increases expression
increases methylation
ISO manganese chloride results in increased expression of ARHGEF4 mRNA
manganese chloride results in increased methylation of ARHGEF4 gene
CTD PMID:17175027 PMID:28801915 NCBI chr 1:34,717,263...34,851,819
Ensembl chr 1:34,717,269...34,852,390
JBrowse link
G Arhgef6 Rac/Cdc42 guanine nucleotide exchange factor 6 increases expression ISO manganese chloride results in increased expression of ARHGEF6 mRNA CTD PMID:28801915 NCBI chr  X:56,276,845...56,384,119
Ensembl chr  X:56,276,845...56,384,089
JBrowse link
G Arhgef7 Rho guanine nucleotide exchange factor decreases expression ISO manganese chloride results in decreased expression of ARHGEF7 mRNA CTD PMID:28801915 NCBI chr 8:11,778,053...11,885,219
Ensembl chr 8:11,777,721...11,885,219
JBrowse link
G Arid3a AT-rich interaction domain 3A increases expression ISO manganese chloride results in increased expression of ARID3A mRNA CTD PMID:28801915 NCBI chr10:79,762,877...79,790,852
Ensembl chr10:79,762,877...79,790,852
JBrowse link
G Arl4c ADP-ribosylation factor-like 4C increases methylation
increases expression
ISO manganese chloride results in increased methylation of ARL4C gene
manganese chloride results in increased expression of ARL4C mRNA
CTD PMID:28801915 NCBI chr 1:88,625,947...88,629,913
Ensembl chr 1:88,600,847...88,629,943
JBrowse link
G Arnt aryl hydrocarbon receptor nuclear translocator multiple interactions EXP ARNT gene mutant form inhibits the reaction [manganese chloride results in increased secretion of VEGFA protein] CTD PMID:19263519 NCBI chr 3:95,341,674...95,404,551
Ensembl chr 3:95,341,699...95,404,551
JBrowse link
G Asb5 ankyrin repeat and SOCs box-containing 5 decreases expression ISO manganese chloride results in decreased expression of ASB5 mRNA CTD PMID:28801915 NCBI chr 8:55,003,366...55,040,877
Ensembl chr 8:54,982,615...55,040,910
JBrowse link
G Asns asparagine synthetase increases expression ISO manganese chloride results in increased expression of ASNS mRNA CTD PMID:28801915 NCBI chr 6:7,675,169...7,693,209
Ensembl chr 6:7,675,169...7,693,254
JBrowse link
G Ass1 argininosuccinate synthetase 1 increases expression ISO manganese chloride results in increased expression of ASS1 mRNA CTD PMID:28801915 NCBI chr 2:31,360,282...31,410,682
Ensembl chr 2:31,360,219...31,410,684
JBrowse link
G Aste1 asteroid homolog 1 increases expression ISO manganese chloride results in increased expression of ASTE1 mRNA CTD PMID:28801915 NCBI chr 9:105,272,533...105,285,497
Ensembl chr 9:105,272,591...105,289,428
JBrowse link
G Atf1 activating transcription factor 1 multiple interactions
increases phosphorylation
ISO SB 203580 inhibits the reaction [manganese chloride results in increased phosphorylation of ATF1 protein] CTD PMID:16787641 NCBI chr15:100,125,729...100,159,129
Ensembl chr15:100,125,700...100,159,125
JBrowse link
G Atf2 activating transcription factor 2 increases activity
increases phosphorylation
ISO manganese chloride results in increased activity of ATF2 protein
manganese chloride results in increased phosphorylation of ATF2 protein
CTD PMID:19084589 PMID:20152896 NCBI chr 2:73,646,853...73,723,094
Ensembl chr 2:73,646,853...73,722,983
JBrowse link
G Atf4 activating transcription factor 4 multiple interactions
increases expression
ISO manganese chloride promotes the reaction [EIF2AK3 protein results in increased expression of ATF4 mRNA]; SNCA protein promotes the reaction [manganese chloride results in increased expression of ATF4 mRNA]
manganese chloride results in increased expression of ATF4 mRNA; manganese chloride results in increased expression of ATF4 protein
CTD PMID:23934647 PMID:23948121 NCBI chr15:80,139,385...80,141,746
Ensembl chr15:80,139,385...80,141,742
JBrowse link
G Atf6 activating transcription factor 6 decreases expression
increases expression
ISO manganese chloride results in decreased expression of ATF6 mRNA
manganese chloride results in increased expression of ATF6 protein
CTD PMID:17175027 PMID:25732873 NCBI chr 1:170,532,026...170,696,414
Ensembl chr 1:170,532,243...170,695,340
JBrowse link
G Atm ataxia telangiectasia mutated decreases expression ISO manganese chloride results in decreased expression of ATM mRNA CTD PMID:17175027 NCBI chr 9:53,348,422...53,448,125
Ensembl chr 9:53,350,449...53,448,040
JBrowse link
G Atoh8 atonal bHLH transcription factor 8 decreases expression ISO manganese chloride results in decreased expression of ATOH8 mRNA CTD PMID:26745496 PMID:28801915 NCBI chr 6:72,183,158...72,212,765
Ensembl chr 6:72,183,161...72,212,561
JBrowse link
G Atp1a2 ATPase, Na+/K+ transporting, alpha 2 polypeptide multiple interactions EXP [manganese chloride results in increased abundance of Manganese] which results in increased expression of ATP1A2 protein CTD PMID:37598760 NCBI chr 1:172,099,276...172,125,631
Ensembl chr 1:172,099,276...172,125,631
JBrowse link
G Atp1a3 ATPase, Na+/K+ transporting, alpha 3 polypeptide multiple interactions EXP [manganese chloride results in increased abundance of Manganese] which affects the expression of ATP1A3 protein CTD PMID:37598760 NCBI chr 7:24,677,592...24,705,338
Ensembl chr 7:24,677,592...24,705,383
JBrowse link
G Atp2a3 ATPase, Ca++ transporting, ubiquitous increases methylation ISO manganese chloride results in increased methylation of ATP2A3 gene CTD PMID:28801915 NCBI chr11:72,851,995...72,883,869
Ensembl chr11:72,851,995...72,883,870
JBrowse link
G Atp2b2 ATPase, Ca++ transporting, plasma membrane 2 increases methylation
decreases expression
ISO manganese chloride results in increased methylation of ATP2B2 gene
manganese chloride results in decreased expression of ATP2B2 mRNA
CTD PMID:27913844 NCBI chr 6:113,720,803...114,019,574
Ensembl chr 6:113,720,792...114,019,574
JBrowse link
G Atp2b4 ATPase, Ca++ transporting, plasma membrane 4 increases expression ISO manganese chloride results in increased expression of ATP2B4 mRNA CTD PMID:28801915 NCBI chr 1:133,630,416...133,728,755
Ensembl chr 1:133,627,195...133,728,779
JBrowse link
G Atp5f1c ATP synthase F1 subunit gamma decreases expression ISO manganese chloride results in decreased expression of ATP5F1C mRNA CTD PMID:22281203 NCBI chr 2:10,060,841...10,085,321
Ensembl chr 2:10,060,827...10,085,321
JBrowse link
G Atp6v1a ATPase, H+ transporting, lysosomal V1 subunit A increases expression ISO manganese chloride results in increased expression of ATP6V1A mRNA CTD PMID:28801915 NCBI chr16:43,905,765...43,960,055
Ensembl chr16:43,905,765...43,960,068
JBrowse link
G Atp6v1e2 ATPase, H+ transporting, lysosomal V1 subunit E2 decreases expression ISO
EXP
manganese chloride results in decreased expression of ATP6V1E2 mRNA CTD PMID:28801915 NCBI chr17:87,251,537...87,255,315
Ensembl chr17:87,251,537...87,255,325
JBrowse link
G Atp6v1h ATPase, H+ transporting, lysosomal V1 subunit H multiple interactions EXP [manganese chloride results in increased abundance of Manganese] which results in decreased expression of ATP6V1H mRNA; U 0126 inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in decreased expression of ATP6V1H mRNA] CTD PMID:31690173 NCBI chr 1:5,153,201...5,233,438
Ensembl chr 1:5,140,241...5,232,752
JBrowse link
G Atp7a ATPase, copper transporting, alpha polypeptide decreases expression
affects localization
ISO manganese chloride results in decreased expression of ATP7A mRNA; manganese chloride results in decreased expression of ATP7A protein
manganese chloride affects the localization of ATP7A protein
CTD PMID:24614235 NCBI chr  X:105,070,830...105,171,766
Ensembl chr  X:105,070,882...105,168,532
JBrowse link
G Atp7b ATPase, copper transporting, beta polypeptide affects localization
decreases expression
ISO manganese chloride affects the localization of ATP7B protein
manganese chloride results in decreased expression of ATP7B mRNA; manganese chloride results in decreased expression of ATP7B protein
CTD PMID:24614235 NCBI chr 8:22,482,799...22,550,347
Ensembl chr 8:22,482,801...22,550,321
JBrowse link
G Atp8a1 ATPase phospholipid transporting 8A1 decreases expression ISO manganese chloride results in decreased expression of ATP8A1 mRNA CTD PMID:17175027 NCBI chr 5:67,775,482...68,004,822
Ensembl chr 5:67,775,483...68,004,777
JBrowse link
G Avil advillin increases methylation
decreases expression
ISO manganese chloride results in increased methylation of AVIL gene
manganese chloride results in decreased expression of AVIL mRNA
CTD PMID:28801915 NCBI chr10:126,835,933...126,856,857
Ensembl chr10:126,836,578...126,856,863
JBrowse link
G Axin2 axin 2 increases expression ISO manganese chloride results in increased expression of AXIN2 mRNA CTD PMID:28801915 NCBI chr11:108,808,687...108,841,609
Ensembl chr11:108,811,175...108,841,609
JBrowse link
G Bach1 BTB and CNC homology 1, basic leucine zipper transcription factor 1 increases expression ISO manganese chloride results in increased expression of BACH1 mRNA CTD PMID:28801915 NCBI chr16:87,495,842...87,530,234
Ensembl chr16:87,495,833...87,530,234
JBrowse link
G Bax BCL2-associated X protein increases expression
multiple interactions
ISO
EXP
manganese chloride results in increased expression of BAX mRNA; manganese chloride results in increased expression of BAX protein
[manganese chloride results in increased abundance of Manganese] which results in increased expression of BAX protein; [Plant Extracts co-treated with manganese chloride] affects the expression of BAX protein; benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased expression of BAX protein]; Estradiol inhibits the reaction [manganese chloride results in increased expression of BAX protein]; Tamoxifen inhibits the reaction [manganese chloride results in increased expression of BAX protein]
[manganese chloride results in increased abundance of Manganese] promotes the reaction [Ethanol results in increased expression of BAX protein]; [manganese chloride results in increased abundance of Manganese] which results in increased expression of BAX protein; Ethanol promotes the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased expression of BAX protein]; manganese chloride results in increased expression of and affects the localization of BAX protein
NTF3 protein inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased expression of BAX protein]
CTD PMID:17623882 PMID:21704098 PMID:25732873 PMID:26064043 PMID:29183790 More... NCBI chr 7:45,111,124...45,116,332
Ensembl chr 7:45,111,121...45,116,322
JBrowse link
G Bcl2 B cell leukemia/lymphoma 2 decreases expression
multiple interactions
increases nitrosation
increases expression
ISO
EXP
manganese chloride results in decreased expression of BCL2 mRNA; manganese chloride results in decreased expression of BCL2 protein
[manganese chloride results in increased abundance of Manganese] which results in decreased expression of BCL2 protein; [Plant Extracts co-treated with manganese chloride] affects the expression of BCL2 protein; Estradiol inhibits the reaction [manganese chloride results in decreased expression of BCL2 protein]; Tamoxifen inhibits the reaction [manganese chloride results in decreased expression of BCL2 protein]
[manganese chloride results in increased abundance of Manganese] promotes the reaction [Ethanol results in decreased expression of BCL2 protein]; [manganese chloride results in increased abundance of Manganese] which results in decreased expression of BCL2 protein; Ethanol promotes the reaction [[manganese chloride results in increased abundance of Manganese] which results in decreased expression of BCL2 protein]; manganese chloride results in decreased expression of and affects the localization of BCL2 protein
manganese chloride results in increased nitrosation of BCL2 protein
[manganese chloride results in increased abundance of Manganese] which results in decreased expression of BCL2 mRNA; corynoxine B inhibits the reaction [manganese chloride promotes the reaction [BCL2 protein binds to BECN1 protein]]; manganese chloride promotes the reaction [BCL2 protein binds to BECN1 protein]; manganese chloride results in increased expression of and results in decreased phosphorylation of BCL2 protein; N-((3-(aminomethyl)phenyl)methyl)ethanimidamide inhibits the reaction [manganese chloride promotes the reaction [BCL2 protein binds to BECN1 protein]]; N-((3-(aminomethyl)phenyl)methyl)ethanimidamide inhibits the reaction [manganese chloride results in increased expression of and results in decreased phosphorylation of BCL2 protein]; N-((3-(aminomethyl)phenyl)methyl)ethanimidamide inhibits the reaction [manganese chloride results in increased nitrosation of BCL2 protein]
manganese chloride results in increased expression of BCL2 mRNA
manganese chloride results in increased expression of BCL2 protein
CTD PMID:17623882 PMID:21704098 PMID:25732873 PMID:26064043 PMID:28801915 More... NCBI chr 1:106,465,906...106,642,020
Ensembl chr 1:106,465,908...106,642,004
JBrowse link
G Bcl2l1 BCL2-like 1 decreases expression ISO manganese chloride results in decreased expression of BCL2L1 protein CTD PMID:27107493 NCBI chr 2:152,600,652...152,673,632
Ensembl chr 2:152,622,588...152,673,648
JBrowse link
G Bcl2l11 BCL2 like 11 increases expression
decreases expression
ISO manganese chloride results in increased expression of BCL2L11 protein
manganese chloride results in decreased expression of BCL2L11 mRNA
CTD PMID:25732873 PMID:28801915 NCBI chr 2:127,967,958...128,004,467
Ensembl chr 2:127,967,958...128,004,467
JBrowse link
G Bcl6b B cell CLL/lymphoma 6, member B increases expression ISO manganese chloride results in increased expression of BCL6B mRNA CTD PMID:28801915 NCBI chr11:70,114,953...70,120,624
Ensembl chr11:70,114,954...70,120,624
JBrowse link
G Bdkrb2 bradykinin receptor, beta 2 increases expression ISO manganese chloride results in increased expression of BDKRB2 mRNA CTD PMID:28801915 NCBI chr12:105,529,431...105,561,503
Ensembl chr12:105,529,485...105,561,496
JBrowse link
G Bdnf brain derived neurotrophic factor decreases expression
increases methylation
increases expression
multiple interactions
EXP
ISO
manganese chloride results in decreased expression of BDNF mRNA
manganese chloride results in increased methylation of BDNF gene
manganese chloride results in increased expression of BDNF mRNA
[manganese chloride results in increased abundance of Manganese] which results in decreased expression of BDNF protein; [manganese chloride results in increased abundance of Manganese] which results in increased expression of BDNF mRNA; CREB1 protein affects the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased expression of BDNF mRNA]
CTD PMID:25698507 PMID:28801915 PMID:30951808 PMID:32659473 NCBI chr 2:109,505,045...109,557,388
Ensembl chr 2:109,505,045...109,557,352
JBrowse link
G Becn1 beclin 1, autophagy related increases expression
multiple interactions
decreases expression
affects expression
ISO manganese chloride results in increased expression of BECN1 protein
wortmannin inhibits the reaction [manganese chloride results in increased expression of BECN1 protein]
manganese chloride results in decreased expression of BECN1 protein
corynoxine B affects the reaction [manganese chloride affects the reaction [HMGB1 protein binds to BECN1 protein]]; corynoxine B inhibits the reaction [manganese chloride promotes the reaction [BCL2 protein binds to BECN1 protein]]; manganese chloride affects the reaction [HMGB1 protein binds to BECN1 protein]; manganese chloride promotes the reaction [BCL2 protein binds to BECN1 protein]; N-((3-(aminomethyl)phenyl)methyl)ethanimidamide inhibits the reaction [manganese chloride promotes the reaction [BCL2 protein binds to BECN1 protein]]
manganese chloride affects the expression of BECN1 protein
CTD PMID:23604964 PMID:28856835 PMID:30578841 PMID:30672645 NCBI chr11:101,179,084...101,193,112
Ensembl chr11:101,176,778...101,193,112
JBrowse link
G Bhlhe40 basic helix-loop-helix family, member e40 increases expression ISO manganese chloride results in increased expression of BHLHE40 mRNA CTD PMID:28801915 NCBI chr 6:108,637,590...108,643,886
Ensembl chr 6:108,637,590...108,643,886
JBrowse link
G Bid BH3 interacting domain death agonist increases cleavage
multiple interactions
increases expression
ISO manganese chloride results in increased cleavage of BID protein
bafilomycin A1 inhibits the reaction [manganese chloride results in increased expression of BID protein modified form]; bafilomycin A1 inhibits the reaction [manganese chloride results in increased expression of BID protein]; CA 074 methyl ester inhibits the reaction [manganese chloride results in increased expression of BID protein modified form]; CA 074 methyl ester inhibits the reaction [manganese chloride results in increased expression of BID protein]; pepstatin inhibits the reaction [manganese chloride results in increased expression of BID protein modified form]; pepstatin inhibits the reaction [manganese chloride results in increased expression of BID protein]
manganese chloride results in increased expression of BID protein; manganese chloride results in increased expression of BID protein modified form
CTD PMID:21704098 PMID:28378122 NCBI chr 6:120,870,080...120,894,074
Ensembl chr 6:120,868,891...120,893,814
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 multiple interactions
decreases expression
ISO Lithium Chloride inhibits the reaction [manganese chloride results in decreased expression of BIRC5 mRNA] CTD PMID:24464479 NCBI chr11:117,740,063...117,746,569
Ensembl chr11:117,740,077...117,746,569
JBrowse link
G Birc7 baculoviral IAP repeat-containing 7 increases expression ISO manganese chloride results in increased expression of BIRC7 mRNA CTD PMID:28801915 NCBI chr 2:180,570,402...180,575,803
Ensembl chr 2:180,570,816...180,575,803
JBrowse link
G Bloc1s3 biogenesis of lysosomal organelles complex-1, subunit 3 increases expression ISO manganese chloride results in increased expression of BLOC1S3 mRNA CTD PMID:28801915 NCBI chr 7:19,239,708...19,242,295
Ensembl chr 7:19,238,411...19,242,292
JBrowse link
G Blvra biliverdin reductase A increases expression ISO manganese chloride results in increased expression of BLVRA mRNA CTD PMID:22281203 NCBI chr 2:126,912,549...126,939,004
Ensembl chr 2:126,912,585...126,939,004
JBrowse link
G Bmal1 basic helix-loop-helix ARNT like 1 decreases expression ISO manganese chloride results in decreased expression of BMAL1 mRNA CTD PMID:28511934 NCBI chr 7:112,777,820...112,913,333
Ensembl chr 7:112,806,672...112,913,333
JBrowse link
G Bmf BCL2 modifying factor decreases expression ISO manganese chloride results in decreased expression of BMF mRNA CTD PMID:28801915 NCBI chr 2:118,359,238...118,385,240
Ensembl chr 2:118,359,238...118,380,168
JBrowse link
G Bmp4 bone morphogenetic protein 4 increases expression EXP manganese chloride results in increased expression of BMP4 mRNA CTD PMID:17467022 NCBI chr14:46,620,982...46,628,126
Ensembl chr14:46,620,977...46,628,126
JBrowse link
G Bnip3 BCL2/adenovirus E1B interacting protein 3 multiple interactions
affects response to substance
EXP [N-(3-(aminomethyl)benzyl)acetamidine results in decreased activity of NOS2 protein] inhibits the reaction [manganese chloride results in increased expression of BNIP3 protein]; Acetylcysteine inhibits the reaction [manganese chloride results in increased expression of BNIP3 protein]; BNIP3 protein affects the reaction [manganese chloride affects the localization of CYCS protein]; Cycloheximide inhibits the reaction [manganese chloride results in increased expression of BNIP3 protein]; Dactinomycin inhibits the reaction [manganese chloride results in increased expression of BNIP3 protein]; Glutathione inhibits the reaction [manganese chloride results in increased expression of BNIP3 protein]; manganese chloride results in increased expression of and affects the localization of BNIP3 protein
BNIP3 protein affects the susceptibility to manganese chloride
CTD PMID:19442826 NCBI chr 7:138,492,565...138,511,235
Ensembl chr 7:138,492,565...138,511,248
JBrowse link
G Bpifb6 BPI fold containing family B, member 6 increases expression ISO manganese chloride results in increased expression of BPIFB6 mRNA CTD PMID:28801915 NCBI chr 2:153,742,308...153,754,715
Ensembl chr 2:153,742,308...153,754,715
JBrowse link
G Bsn bassoon increases expression ISO manganese chloride results in increased expression of BSN mRNA CTD PMID:28801915 NCBI chr 9:107,973,221...108,067,618
Ensembl chr 9:107,973,221...108,067,583
JBrowse link
G Bub1 BUB1, mitotic checkpoint serine/threonine kinase decreases expression ISO manganese chloride results in decreased expression of BUB1 mRNA CTD PMID:17175027 NCBI chr 2:127,642,117...127,673,790
Ensembl chr 2:127,643,036...127,673,785
JBrowse link
G C1qtnf4 C1q and tumor necrosis factor related protein 4 increases expression ISO manganese chloride results in increased expression of C1QTNF4 mRNA CTD PMID:28801915 NCBI chr 2:90,713,132...90,720,870
Ensembl chr 2:90,716,204...90,720,869
JBrowse link
G C2cd4b C2 calcium-dependent domain containing 4B increases expression ISO manganese chloride results in increased expression of C2CD4B mRNA CTD PMID:28801915 NCBI chr 9:67,623,506...67,668,215
Ensembl chr 9:67,666,719...67,668,212
JBrowse link
G Cables1 CDK5 and Abl enzyme substrate 1 decreases expression ISO manganese chloride results in decreased expression of CABLES1 mRNA CTD PMID:28801915 NCBI chr18:11,972,600...12,078,681
Ensembl chr18:11,972,277...12,078,687
JBrowse link
G Calcoco2 calcium binding and coiled-coil domain 2 increases expression ISO manganese chloride results in increased expression of CALCOCO2 mRNA CTD PMID:17175027 NCBI chr11:95,990,195...96,015,362
Ensembl chr11:95,990,152...96,002,790
JBrowse link
G Cald1 caldesmon 1 increases expression ISO manganese chloride results in increased expression of CALD1 mRNA CTD PMID:28801915 NCBI chr 6:34,575,433...34,752,404
Ensembl chr 6:34,575,435...34,752,408
JBrowse link
G Caly calcyon neuron-specific vesicular protein increases expression ISO manganese chloride results in increased expression of CALY mRNA CTD PMID:28801915 NCBI chr 7:139,649,793...139,662,485
Ensembl chr 7:139,649,793...139,662,461
JBrowse link
G Camkk2 calcium/calmodulin-dependent protein kinase kinase 2, beta increases expression EXP manganese chloride results in increased expression of CAMKK2 mRNA CTD PMID:15295902 NCBI chr 5:122,856,064...122,918,295
Ensembl chr 5:122,869,233...122,917,472
JBrowse link
G Camkv CaM kinase-like vesicle-associated decreases expression ISO manganese chloride results in decreased expression of CAMKV mRNA CTD PMID:28801915 NCBI chr 9:107,813,097...107,826,882
Ensembl chr 9:107,812,873...107,826,890
JBrowse link
G Camp cathelicidin antimicrobial peptide increases expression ISO manganese chloride results in increased expression of CAMP mRNA CTD PMID:28801915 NCBI chr 9:109,676,445...109,678,524
Ensembl chr 9:109,676,447...109,678,685
JBrowse link
G Camta2 calmodulin binding transcription activator 2 increases expression ISO manganese chloride results in increased expression of CAMTA2 mRNA CTD PMID:28801915 NCBI chr11:70,560,288...70,578,966
Ensembl chr11:70,560,289...70,578,931
JBrowse link
G Capn5 calpain 5 increases expression ISO manganese chloride results in increased expression of CAPN5 mRNA CTD PMID:28801915 NCBI chr 7:97,770,766...97,828,148
Ensembl chr 7:97,770,766...97,827,481
JBrowse link
G Car5b carbonic anhydrase 5b, mitochondrial decreases expression ISO manganese chloride results in decreased expression of CAR5B mRNA CTD PMID:28801915 NCBI chr  X:162,759,818...162,811,006
Ensembl chr  X:162,759,818...162,810,993
JBrowse link
G Car8 carbonic anhydrase 8 increases expression ISO manganese chloride results in increased expression of CAR8 mRNA CTD PMID:26745496 NCBI chr 4:8,141,491...8,239,226
Ensembl chr 4:8,143,362...8,239,041
JBrowse link
G Card14 caspase recruitment domain family, member 14 increases methylation ISO manganese chloride results in increased methylation of CARD14 gene CTD PMID:27913844 NCBI chr11:119,197,923...119,236,205
Ensembl chr11:119,198,594...119,236,201
JBrowse link
G Card9 caspase recruitment domain family, member 9 decreases expression ISO manganese chloride results in decreased expression of CARD9 mRNA CTD PMID:28801915 NCBI chr 2:26,242,199...26,250,957
Ensembl chr 2:26,242,188...26,250,930
JBrowse link
G Casp12 caspase 12 multiple interactions
increases expression
increases cleavage
ISO
EXP
Deferoxamine promotes the reaction [manganese chloride results in increased cleavage of and results in increased activity of CASP12 protein]; manganese chloride results in increased cleavage of and results in increased activity of CASP12 protein
manganese chloride results in increased expression of CASP12 mRNA; manganese chloride results in increased expression of CASP12 protein
SNCA protein promotes the reaction [manganese chloride results in increased expression of CASP12 protein]
manganese chloride results in increased cleavage of CASP12 protein
Plant Extracts inhibits the reaction [manganese chloride results in increased cleavage of CASP12 protein]
CTD PMID:23764342 PMID:23934647 PMID:23948121 PMID:25732873 PMID:26064043 More... NCBI chr 9:5,345,419...5,373,034
Ensembl chr 9:5,345,430...5,373,032
JBrowse link
G Casp2 caspase 2 increases expression ISO manganese chloride results in increased expression of CASP2 mRNA CTD PMID:28801915 NCBI chr 6:42,241,942...42,259,442
Ensembl chr 6:42,241,919...42,259,442
JBrowse link
G Casp3 caspase 3 increases cleavage
multiple interactions
increases expression
increases activity
increases methylation
EXP
ISO
manganese chloride results in increased cleavage of CASP3 protein
[manganese chloride results in increased abundance of Manganese] promotes the reaction [Ethanol results in increased expression of CASP3 protein]; [manganese chloride results in increased abundance of Manganese] which results in increased cleavage of CASP3 protein; [manganese chloride results in increased abundance of Manganese] which results in increased expression of CASP3 protein; Acetylcysteine inhibits the reaction [manganese chloride results in increased expression of CASP3 protein modified form]; bafilomycin A1 inhibits the reaction [manganese chloride results in increased cleavage of CASP3 protein]; CA 074 methyl ester inhibits the reaction [manganese chloride results in increased cleavage of CASP3 protein]; Ethanol promotes the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased expression of CASP3 protein]; GW 506033X inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased cleavage of CASP3 protein]; Lithium Chloride inhibits the reaction [manganese chloride results in increased activity of CASP3 protein]; pepstatin inhibits the reaction [manganese chloride results in increased cleavage of CASP3 protein]; pyrazolanthrone inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased cleavage of CASP3 protein]; pyrazolanthrone inhibits the reaction [manganese chloride results in increased cleavage of CASP3 protein]; pyrazolanthrone inhibits the reaction [manganese chloride results in increased expression of CASP3 protein]; Quercetin inhibits the reaction [manganese chloride results in increased activity of CASP3 protein]; rhodioloside inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased cleavage of CASP3 protein]; U 0126 inhibits the reaction [manganese chloride results in increased expression of CASP3 mRNA]; U 0126 inhibits the reaction [manganese chloride results in increased expression of CASP3 protein]
manganese chloride results in increased expression of CASP3 mRNA; manganese chloride results in increased expression of CASP3 protein; manganese chloride results in increased expression of CASP3 protein modified form
[manganese chloride results in increased abundance of Manganese] which results in increased cleavage of CASP3 protein; Plant Extracts inhibits the reaction [manganese chloride results in increased cleavage of CASP3 protein]; PRNP protein inhibits the reaction [manganese chloride results in increased activity of CASP3 protein]
Deferoxamine promotes the reaction [manganese chloride results in increased activity of CASP3 protein]; SNCA protein inhibits the reaction [manganese chloride results in increased activity of CASP3 protein]
manganese chloride results in increased methylation of CASP3 gene
CTD PMID:16787641 PMID:17483122 PMID:18178165 PMID:19815061 PMID:23764342 More... NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724
JBrowse link
G Casp4 caspase 4, apoptosis-related cysteine peptidase increases expression ISO manganese chloride results in increased expression of CASP4 mRNA CTD PMID:28801915 NCBI chr 9:5,308,816...5,336,791
Ensembl chr 9:5,308,828...5,336,783
JBrowse link
G Casp8 caspase 8 increases cleavage
multiple interactions
ISO manganese chloride results in increased cleavage of CASP8 protein
bafilomycin A1 inhibits the reaction [manganese chloride results in increased cleavage of CASP8 protein]; CA 074 methyl ester inhibits the reaction [manganese chloride results in increased cleavage of CASP8 protein]; pepstatin inhibits the reaction [manganese chloride results in increased cleavage of CASP8 protein]
CTD PMID:21704098 PMID:28378122 NCBI chr 1:58,834,553...58,886,663
Ensembl chr 1:58,834,533...58,886,662
JBrowse link
G Casp9 caspase 9 increases activity
multiple interactions
increases cleavage
EXP
ISO
manganese chloride results in increased activity of CASP9 protein
PRNP protein inhibits the reaction [manganese chloride results in increased activity of CASP9 protein]
SNCA protein inhibits the reaction [manganese chloride results in increased activity of CASP9 protein]
manganese chloride results in increased cleavage of CASP9 protein
bafilomycin A1 inhibits the reaction [manganese chloride results in increased cleavage of CASP9 protein]; CA 074 methyl ester inhibits the reaction [manganese chloride results in increased cleavage of CASP9 protein]; pepstatin inhibits the reaction [manganese chloride results in increased cleavage of CASP9 protein]
CTD PMID:16787641 PMID:17483122 PMID:21704098 PMID:25416158 PMID:28378122 NCBI chr 4:141,520,923...141,543,289
Ensembl chr 4:141,520,923...141,543,287
JBrowse link
G Cat catalase decreases activity
multiple interactions
decreases expression
ISO
EXP
manganese chloride results in decreased activity of CAT protein
[manganese chloride results in increased abundance of Manganese] which results in decreased activity of CAT protein; [Plant Extracts co-treated with manganese chloride] results in increased expression of CAT protein; Estradiol inhibits the reaction [manganese chloride results in decreased expression of CAT protein]; Tamoxifen inhibits the reaction [manganese chloride results in decreased expression of CAT protein]
[manganese chloride results in increased abundance of Manganese] promotes the reaction [Ethanol results in decreased activity of CAT protein]; [manganese chloride results in increased abundance of Manganese] which results in decreased activity of CAT protein; [manganese chloride results in increased abundance of Manganese] which results in decreased expression of CAT protein; Ethanol promotes the reaction [[manganese chloride results in increased abundance of Manganese] which results in decreased activity of CAT protein]; Quercetin inhibits the reaction [manganese chloride results in decreased activity of CAT protein]; Silymarin inhibits the reaction [manganese chloride results in decreased activity of CAT protein]
CTD PMID:20503066 PMID:22033861 PMID:22192907 PMID:26064043 PMID:28040552 More... NCBI chr 2:103,284,249...103,315,498
Ensembl chr 2:103,284,194...103,315,505
JBrowse link
G Catip ciliogenesis associated TTC17 interacting protein increases expression ISO manganese chloride results in increased expression of CATIP mRNA CTD PMID:28801915 NCBI chr 1:74,401,272...74,408,482
Ensembl chr 1:74,401,267...74,408,480
JBrowse link
G Catsperd cation channel sperm associated auxiliary subunit delta increases expression ISO manganese chloride results in increased expression of CATSPERD mRNA CTD PMID:28801915 NCBI chr17:56,933,917...56,971,456
Ensembl chr17:56,935,143...56,971,456
JBrowse link
G Cav2 caveolin 2 decreases expression ISO manganese chloride results in decreased expression of CAV2 mRNA CTD PMID:28801915 NCBI chr 6:17,281,184...17,289,129
Ensembl chr 6:17,281,184...17,289,114
JBrowse link
G Cbarp calcium channel, voltage-dependent, beta subunit associated regulatory protein increases expression ISO manganese chloride results in increased expression of DOS mRNA CTD PMID:28801915 NCBI chr10:79,966,268...79,976,189
Ensembl chr10:79,966,285...79,976,669
JBrowse link
G Cbs cystathionine beta-synthase decreases expression ISO manganese chloride results in decreased expression of CBS mRNA CTD PMID:28801915 NCBI chr17:31,831,602...31,856,170
Ensembl chr17:31,827,868...31,856,212
JBrowse link
G Ccdc15 coiled-coil domain containing 15 increases expression ISO manganese chloride results in increased expression of CCDC15 mRNA CTD PMID:28801915 NCBI chr 9:37,178,758...37,262,508
Ensembl chr 9:37,187,131...37,259,728
JBrowse link
G Ccdc175 coiled-coil domain containing 175 increases expression ISO manganese chloride results in increased expression of CCDC175 mRNA CTD PMID:28801915 NCBI chr12:72,148,066...72,231,803
Ensembl chr12:72,148,074...72,231,803
JBrowse link
G Ccdc96 coiled-coil domain containing 96 increases expression ISO manganese chloride results in increased expression of CCDC96 mRNA CTD PMID:28801915 NCBI chr 5:36,641,932...36,645,515
Ensembl chr 5:36,641,932...36,645,516
JBrowse link
G Ccl17 C-C motif chemokine ligand 17 increases expression ISO manganese chloride results in increased expression of CCL17 mRNA CTD PMID:28801915 NCBI chr 8:95,535,996...95,538,666
Ensembl chr 8:95,537,081...95,538,664
JBrowse link
G Ccl19 C-C motif chemokine ligand 19 increases expression ISO manganese chloride results in increased expression of CCL19 mRNA CTD PMID:28801915 NCBI chr 4:42,754,525...42,756,558
Ensembl chr 4:42,754,525...42,756,577
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions
decreases secretion
ISO
EXP
manganese chloride inhibits the reaction [CCL2 protein results in increased expression of ICAM1 protein]; manganese chloride inhibits the reaction [Glucose results in increased secretion of CCL2 protein]
manganese chloride results in decreased secretion of CCL2 protein
CTD PMID:23329836 NCBI chr11:81,926,403...81,928,278
Ensembl chr11:81,926,397...81,928,279
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 increases expression ISO manganese chloride results in increased expression of CCL5 mRNA CTD PMID:28801915 NCBI chr11:83,416,604...83,421,344
Ensembl chr11:83,416,604...83,421,344
JBrowse link
G Ccl7 C-C motif chemokine ligand 7 increases expression ISO manganese chloride results in increased expression of CCL7 mRNA CTD PMID:17175027 PMID:28801915 NCBI chr11:81,936,538...81,938,351
Ensembl chr11:81,936,538...81,938,351
JBrowse link
G Ccn2 cellular communication network factor 2 increases expression
increases methylation
EXP
ISO
manganese chloride results in increased expression of CCN2 mRNA
manganese chloride results in increased methylation of CCN2 gene
CTD PMID:17467022 PMID:28801915 NCBI chr10:24,471,340...24,474,581
Ensembl chr10:24,471,340...24,474,581
JBrowse link
G Ccna1 cyclin A1 increases expression ISO manganese chloride results in increased expression of CCNA1 mRNA CTD PMID:26745496 NCBI chr 3:54,952,890...54,965,055
Ensembl chr 3:54,952,890...54,962,922
JBrowse link
G Ccnb1 cyclin B1 multiple interactions EXP
ISO
[manganese chloride results in increased abundance of Manganese] which results in decreased expression of CCNB1 mRNA; [manganese chloride results in increased abundance of Manganese] which results in decreased expression of CCNB1 protein CTD PMID:34822792 PMID:38503349 NCBI chr13:100,915,247...100,922,994
Ensembl chr13:100,915,158...100,923,078
JBrowse link
G Ccnb2 cyclin B2 decreases expression
multiple interactions
ISO
EXP
manganese chloride results in decreased expression of CCNB2 mRNA
[manganese chloride results in increased abundance of Manganese] which results in decreased expression of CCNB2 mRNA; [manganese chloride results in increased abundance of Manganese] which results in decreased expression of CCNB2 protein; YTHDC2 protein inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in decreased expression of CCNB2 mRNA]; YTHDC2 protein inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in decreased expression of CCNB2 protein]
CTD PMID:17175027 PMID:34822792 NCBI chr 9:70,314,971...70,328,836
Ensembl chr 9:70,314,974...70,328,829
JBrowse link
G Ccnd1 cyclin D1 multiple interactions ISO [manganese chloride results in increased abundance of Manganese] which results in increased expression of CCND1 mRNA CTD PMID:38503349 NCBI chr 7:144,483,668...144,493,568
Ensembl chr 7:144,483,668...144,493,662
JBrowse link
G Ccne1 cyclin E1 multiple interactions ISO [manganese chloride results in increased abundance of Manganese] which results in decreased expression of CCNE1 mRNA; [manganese chloride results in increased abundance of Manganese] which results in decreased expression of CCNE1 protein CTD PMID:38503349 NCBI chr 7:37,797,409...37,806,915
Ensembl chr 7:37,797,409...37,806,959
JBrowse link
G Ccng1 cyclin G1 increases expression ISO manganese chloride results in increased expression of CCNG1 mRNA CTD PMID:28801915 NCBI chr11:40,639,379...40,646,044
Ensembl chr11:40,639,379...40,646,138
JBrowse link
G Cd28 CD28 antigen multiple interactions ISO [manganese chloride co-treated with LCK protein] results in increased phosphorylation of CD28 protein; manganese chloride promotes the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of CD28 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [[manganese chloride co-treated with LCK protein] results in increased phosphorylation of CD28 protein] CTD PMID:8662792 NCBI chr 1:60,785,547...60,812,521
Ensembl chr 1:60,755,959...60,812,518
JBrowse link
G Cd44 CD44 antigen increases expression ISO manganese chloride results in increased expression of CD44 mRNA CTD PMID:28801915 NCBI chr 2:102,641,486...102,732,014
Ensembl chr 2:102,641,486...102,732,010
JBrowse link
G Cd48 CD48 antigen increases expression ISO manganese chloride results in increased expression of CD48 mRNA CTD PMID:17175027 NCBI chr 1:171,508,989...171,532,825
Ensembl chr 1:171,509,577...171,532,826
JBrowse link
G Cd6 CD6 antigen decreases expression ISO manganese chloride results in decreased expression of CD6 mRNA CTD PMID:28801915 NCBI chr19:10,766,703...10,807,427
Ensembl chr19:10,766,705...10,807,422
JBrowse link
G Cd74 CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated) increases expression ISO manganese chloride results in increased expression of CD74 mRNA CTD PMID:28801915 NCBI chr18:60,936,921...60,945,724
Ensembl chr18:60,936,920...60,945,724
JBrowse link
G Cd86 CD86 antigen increases expression ISO manganese chloride results in increased expression of CD86 protein CTD PMID:15737199 NCBI chr16:36,389,318...36,486,439
Ensembl chr16:36,424,231...36,486,443
JBrowse link
G Cd8b1 CD8 subunit beta 1 increases expression ISO manganese chloride results in increased expression of CD8B mRNA; manganese chloride results in increased expression of CD8B1 mRNA CTD PMID:17175027 NCBI chr 6:71,299,772...71,314,476
Ensembl chr 6:71,299,772...71,314,478
JBrowse link
G Cdc42ep3 CDC42 effector protein 3 increases expression ISO manganese chloride results in increased expression of CDC42EP3 mRNA CTD PMID:28801915 NCBI chr17:79,641,152...79,662,520
Ensembl chr17:79,641,156...79,662,520
JBrowse link
G Cdhr4 cadherin-related family member 4 decreases expression ISO manganese chloride results in decreased expression of CDHR4 mRNA CTD PMID:28801915 NCBI chr 9:107,869,656...107,876,880
Ensembl chr 9:107,869,696...107,876,883
JBrowse link
G Cdkn1a cyclin dependent kinase inhibitor 1A multiple interactions
increases expression
affects localization
ISO Cycloheximide inhibits the reaction [manganese chloride results in increased expression of CDKN1A protein]
manganese chloride results in increased expression of CDKN1A mRNA; manganese chloride results in increased expression of CDKN1A protein
manganese chloride affects the localization of CDKN1A protein
CTD PMID:22542671 PMID:28801915 NCBI chr17:29,309,953...29,319,696
Ensembl chr17:29,309,950...29,319,701
JBrowse link
G Cdkn1c cyclin dependent kinase inhibitor 1C decreases expression ISO manganese chloride results in decreased expression of CDKN1C mRNA CTD PMID:28801915 NCBI chr 7:143,012,076...143,014,735
Ensembl chr 7:143,012,076...143,014,787
JBrowse link
G Cdkn2b cyclin dependent kinase inhibitor 2B increases expression ISO manganese chloride results in increased expression of CDKN2B mRNA CTD PMID:28801915 NCBI chr 4:89,224,526...89,229,269
Ensembl chr 4:89,224,536...89,229,276
JBrowse link
G Cdkn2c cyclin dependent kinase inhibitor 2C decreases expression ISO manganese chloride results in decreased expression of CDKN2C mRNA CTD PMID:17175027 NCBI chr 4:109,518,073...109,523,953
Ensembl chr 4:109,518,073...109,524,386
JBrowse link
G Cdkn3 cyclin dependent kinase inhibitor 3 decreases expression ISO manganese chloride results in decreased expression of CDKN3 mRNA CTD PMID:17175027 NCBI chr14:46,997,912...47,008,987
Ensembl chr14:46,997,998...47,009,126
JBrowse link
G Cdnf cerebral dopamine neurotrophic factor increases expression ISO manganese chloride results in increased expression of CDNF mRNA CTD PMID:28801915 NCBI chr 2:3,514,102...3,527,413
Ensembl chr 2:3,514,067...3,527,413
JBrowse link
G Cdyl2 chromodomain protein, Y chromosome-like 2 increases expression ISO manganese chloride results in increased expression of CDYL2 mRNA CTD PMID:28801915 NCBI chr 8:117,295,462...117,459,730
Ensembl chr 8:117,301,139...117,459,730
JBrowse link
G Cebpd CCAAT/enhancer binding protein delta increases expression ISO manganese chloride results in increased expression of CEBPD mRNA CTD PMID:17175027 NCBI chr16:15,705,150...15,707,409
Ensembl chr16:15,705,150...15,708,895
JBrowse link
G Celsr1 cadherin, EGF LAG seven-pass G-type receptor 1 increases expression ISO manganese chloride results in increased expression of CELSR1 mRNA CTD PMID:17175027 NCBI chr15:85,782,959...85,918,424
Ensembl chr15:85,783,130...85,918,404
JBrowse link
G Cep112 centrosomal protein 112 increases expression ISO manganese chloride results in increased expression of CEP112 mRNA CTD PMID:28801915 NCBI chr11:108,316,041...108,751,441
Ensembl chr11:108,316,018...108,751,441
JBrowse link
G Cep128 centrosomal protein 128 decreases expression ISO manganese chloride results in decreased expression of CEP128 mRNA CTD PMID:17175027 NCBI chr12:90,965,264...91,351,207
Ensembl chr12:90,965,266...91,351,183
JBrowse link
G Cers1 ceramide synthase 1 increases expression ISO manganese chloride results in increased expression of CERS1 mRNA CTD PMID:28801915 NCBI chr 8:70,768,425...70,784,238
Ensembl chr 8:70,768,425...70,784,242
JBrowse link
G Cers6 ceramide synthase 6 increases expression ISO manganese chloride results in increased expression of CERS6 mRNA CTD PMID:28801915 NCBI chr 2:68,691,489...68,944,628
Ensembl chr 2:68,691,785...68,944,626
JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator increases expression ISO manganese chloride results in increased expression of CFLAR mRNA CTD PMID:28801915 NCBI chr 1:58,750,353...58,798,043
Ensembl chr 1:58,750,667...58,798,043
JBrowse link
G Cftr cystic fibrosis transmembrane conductance regulator increases expression ISO manganese chloride results in increased expression of CFTR mRNA CTD PMID:28801915 NCBI chr 6:18,170,686...18,322,769
Ensembl chr 6:18,170,686...18,322,767
JBrowse link
G Cgref1 cell growth regulator with EF hand domain 1 increases expression ISO manganese chloride results in increased expression of CGREF1 mRNA CTD PMID:28801915 NCBI chr 5:31,090,487...31,102,771
Ensembl chr 5:31,090,487...31,102,935
JBrowse link
G Ch25h cholesterol 25-hydroxylase increases expression ISO manganese chloride results in increased expression of CH25H mRNA CTD PMID:28801915 NCBI chr19:34,451,183...34,452,548
Ensembl chr19:34,451,178...34,452,564
JBrowse link
G Chat choline O-acetyltransferase multiple interactions EXP [manganese chloride results in increased abundance of Manganese] which results in decreased activity of CHAT protein CTD PMID:30738988 NCBI chr14:32,130,160...32,187,866
Ensembl chr14:32,130,160...32,187,946
JBrowse link
G Chml choroideremia-like increases expression ISO manganese chloride results in increased expression of CHML mRNA CTD PMID:28801915 NCBI chr 1:175,509,803...175,520,198
Ensembl chr 1:175,509,803...175,520,467
JBrowse link
G Chmp4b charged multivesicular body protein 4B multiple interactions EXP [manganese chloride results in increased abundance of Manganese] which results in increased expression of CHMP4B protein CTD PMID:35690225 NCBI chr 2:154,498,949...154,536,703
Ensembl chr 2:154,493,625...154,536,705
JBrowse link
G Chrna7 cholinergic receptor, nicotinic, alpha polypeptide 7 decreases expression EXP manganese chloride results in decreased expression of CHRNA7 protein CTD PMID:25874029 NCBI chr 7:62,748,440...62,862,274
Ensembl chr 7:62,748,440...62,862,317
JBrowse link
G Chst10 carbohydrate sulfotransferase 10 increases expression ISO manganese chloride results in increased expression of CHST10 mRNA CTD PMID:28801915 NCBI chr 1:38,902,948...38,937,256
Ensembl chr 1:38,902,948...38,937,242
JBrowse link
G Chuk conserved helix-loop-helix ubiquitous kinase multiple interactions
increases phosphorylation
ISO 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [manganese chloride results in increased phosphorylation of CHUK protein] CTD PMID:22245093 NCBI chr19:44,061,773...44,095,940
Ensembl chr19:44,061,774...44,095,919
JBrowse link
G Ciita class II transactivator increases expression ISO manganese chloride results in increased expression of CIITA mRNA CTD PMID:28801915 NCBI chr16:10,297,877...10,348,928
Ensembl chr16:10,297,923...10,346,282
JBrowse link
G Cish cytokine inducible SH2-containing protein increases expression ISO manganese chloride results in increased expression of CISH mRNA CTD PMID:28801915 NCBI chr 9:107,173,858...107,179,983
Ensembl chr 9:107,173,225...107,179,983
JBrowse link
G Cited1 Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 1 decreases expression ISO manganese chloride results in decreased expression of CITED1 mRNA CTD PMID:28801915 NCBI chr  X:101,290,984...101,295,787
Ensembl chr  X:101,290,987...101,295,787
JBrowse link
G Cks2 CDC28 protein kinase regulatory subunit 2 decreases expression ISO manganese chloride results in decreased expression of CKS2 mRNA CTD PMID:17175027 NCBI chr13:51,799,268...51,804,698
Ensembl chr13:51,799,268...51,804,696
JBrowse link
G Cldn23 claudin 23 increases expression ISO manganese chloride results in increased expression of CLDN23 mRNA CTD PMID:26745496 NCBI chr 8:36,291,863...36,293,713
Ensembl chr 8:36,291,866...36,293,713
JBrowse link
G Cldn4 claudin 4 increases expression ISO manganese chloride results in increased expression of CLDN4 mRNA CTD PMID:28801915 NCBI chr 5:134,973,977...134,975,788
Ensembl chr 5:134,973,973...134,975,788
JBrowse link
G Cldn9 claudin 9 decreases expression ISO manganese chloride results in decreased expression of CLDN9 mRNA CTD PMID:28801915 NCBI chr17:23,901,558...23,903,000
Ensembl chr17:23,901,558...23,903,000
JBrowse link
G Cldnd1 claudin domain containing 1 multiple interactions EXP [manganese chloride results in increased abundance of Manganese] which results in decreased expression of CLDND1 mRNA CTD PMID:35690225 NCBI chr16:58,548,269...58,554,610
Ensembl chr16:58,548,273...58,554,614
JBrowse link
G Clec4f C-type lectin domain family 4, member f increases methylation ISO manganese chloride results in increased methylation of CLEC4F gene CTD PMID:28801915 NCBI chr 6:83,621,524...83,633,098
Ensembl chr 6:83,621,524...83,633,169
JBrowse link
G Clock clock circadian regulator decreases expression ISO manganese chloride results in decreased expression of CLOCK mRNA CTD PMID:28511934 NCBI chr 5:76,357,715...76,452,675
Ensembl chr 5:76,357,715...76,452,639
JBrowse link
G Cmpk2 cytidine/uridine monophosphate kinase 2 increases expression
increases methylation
ISO manganese chloride results in increased expression of CMPK2 mRNA
manganese chloride results in increased methylation of CMPK2 gene
CTD PMID:28801915 NCBI chr12:26,519,121...26,529,836
Ensembl chr12:26,519,203...26,529,836
JBrowse link
G Cnksr1 connector enhancer of kinase suppressor of Ras 1 increases expression ISO manganese chloride results in increased expression of CNKSR1 mRNA CTD PMID:28801915 NCBI chr 4:133,955,352...133,965,737
Ensembl chr 4:133,955,352...133,965,710
JBrowse link
G Cnot2 CCR4-NOT transcription complex, subunit 2 decreases expression ISO manganese chloride results in decreased expression of CNOT2 mRNA CTD PMID:17175027 NCBI chr10:116,321,065...116,418,891
Ensembl chr10:116,321,066...116,417,416
JBrowse link
G Cnot6l CCR4-NOT transcription complex, subunit 6-like increases expression ISO manganese chloride results in increased expression of CNOT6L mRNA CTD PMID:17175027 NCBI chr 5:96,218,192...96,312,044
Ensembl chr 5:96,218,192...96,312,030
JBrowse link
G Cntn4 contactin 4 decreases expression EXP manganese chloride results in decreased expression of CNTN4 mRNA CTD PMID:15295902 NCBI chr 6:105,654,505...106,677,102
Ensembl chr 6:105,654,621...106,676,271
JBrowse link
G Col12a1 collagen, type XII, alpha 1 decreases expression ISO manganese chloride results in decreased expression of COL12A1 mRNA CTD PMID:17175027 NCBI chr 9:79,506,269...79,628,423
Ensembl chr 9:79,506,273...79,626,113
JBrowse link
G Col15a1 collagen, type XV, alpha 1 increases expression ISO manganese chloride results in increased expression of COL15A1 mRNA CTD PMID:28801915 NCBI chr 4:47,207,744...47,313,165
Ensembl chr 4:47,208,161...47,313,167
JBrowse link
G Col17a1 collagen, type XVII, alpha 1 increases expression ISO manganese chloride results in increased expression of COL17A1 mRNA CTD PMID:28801915 NCBI chr19:47,634,783...47,680,460
Ensembl chr19:47,634,783...47,680,533
JBrowse link
G Col18a1 collagen, type XVIII, alpha 1 increases expression EXP manganese chloride results in increased expression of COL18A1 mRNA CTD PMID:17467022 NCBI chr10:76,888,013...77,002,351
Ensembl chr10:76,888,012...77,002,382
JBrowse link
G Col4a5 collagen, type IV, alpha 5 decreases expression ISO manganese chloride results in decreased expression of COL4A5 mRNA CTD PMID:28801915 NCBI chr  X:140,258,367...140,472,232
Ensembl chr  X:140,258,381...140,472,230
JBrowse link
G Col5a2 collagen, type V, alpha 2 increases expression ISO manganese chloride results in increased expression of COL5A2 mRNA CTD PMID:28801915 NCBI chr 1:45,413,491...45,542,442
Ensembl chr 1:45,413,481...45,542,442
JBrowse link
G Col6a1 collagen, type VI, alpha 1 increases expression ISO manganese chloride results in increased expression of COL6A1 mRNA CTD PMID:28801915 NCBI chr10:76,544,626...76,561,869
Ensembl chr10:76,544,626...76,562,002
JBrowse link
G Col7a1 collagen, type VII, alpha 1 increases expression ISO manganese chloride results in increased expression of COL7A1 mRNA CTD PMID:28801915 NCBI chr 9:108,782,654...108,813,943
Ensembl chr 9:108,782,654...108,813,943
JBrowse link
G Col8a1 collagen, type VIII, alpha 1 increases expression ISO manganese chloride results in increased expression of COL8A1 mRNA CTD PMID:28801915 NCBI chr16:57,444,619...57,575,100
Ensembl chr16:57,444,621...57,575,100
JBrowse link
G Colec10 collectin sub-family member 10 decreases expression ISO manganese chloride results in decreased expression of COLEC10 mRNA CTD PMID:28801915 NCBI chr15:54,274,170...54,329,755
Ensembl chr15:54,274,170...54,329,754
JBrowse link
G Colec12 collectin sub-family member 12 decreases expression ISO manganese chloride results in decreased expression of COLEC12 mRNA CTD PMID:28801915 NCBI chr18:9,707,648...9,877,995
Ensembl chr18:9,707,595...9,882,644
JBrowse link
G Copg2 coatomer protein complex, subunit gamma 2 increases expression ISO manganese chloride results in increased expression of COPG2 mRNA CTD PMID:28801915 NCBI chr 6:30,747,552...30,873,712
Ensembl chr 6:30,747,553...30,873,729
JBrowse link
G Cox6a2 cytochrome c oxidase subunit 6A2 increases expression ISO manganese chloride results in increased expression of COX6A2 mRNA CTD PMID:28801915 NCBI chr 7:127,804,607...127,805,538
Ensembl chr 7:127,804,607...127,805,559
JBrowse link
G Cplx2 complexin 2 increases expression ISO manganese chloride results in increased expression of CPLX2 mRNA CTD PMID:28801915 NCBI chr13:54,455,447...54,531,736
Ensembl chr13:54,519,162...54,531,730
JBrowse link
G Cpm carboxypeptidase M decreases expression ISO manganese chloride results in decreased expression of CPM mRNA CTD PMID:17175027 NCBI chr10:117,465,405...117,523,257
Ensembl chr10:117,465,405...117,523,257
JBrowse link
G Cracdl capping protein inhibiting regulator of actin like increases expression ISO manganese chloride results in increased expression of CRACDL mRNA CTD PMID:28801915 NCBI chr 1:37,650,758...37,758,905
Ensembl chr 1:37,650,758...37,759,166
JBrowse link
G Creb1 cAMP responsive element binding protein 1 increases phosphorylation
multiple interactions
ISO
EXP
manganese chloride results in increased phosphorylation of CREB1 protein
1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased phosphorylation of CREB1 protein]; [manganese chloride results in increased abundance of Manganese] which results in increased phosphorylation of CREB1 protein; CREB1 protein affects the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased expression of BDNF mRNA]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased phosphorylation of CREB1 protein]; SB 203580 inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased phosphorylation of CREB1 protein]; SB 203580 inhibits the reaction [manganese chloride results in increased phosphorylation of CREB1 protein]
[manganese chloride results in increased abundance of Manganese] which results in decreased phosphorylation of CREB1 protein; [manganese chloride results in increased abundance of Manganese] which results in increased phosphorylation of CREB1 protein; benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in decreased phosphorylation of CREB1 protein]
[manganese chloride results in increased abundance of Manganese] which results in decreased expression of CREB1 protein; NTF3 protein inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in decreased phosphorylation of CREB1 protein]
CTD PMID:16787641 PMID:30951808 PMID:31676349 PMID:32659473 NCBI chr 1:64,571,963...64,643,707
Ensembl chr 1:64,571,804...64,643,707
JBrowse link
G Crebl2 cAMP responsive element binding protein-like 2 increases expression ISO manganese chloride results in increased expression of CREBL2 mRNA CTD PMID:28801915 NCBI chr 6:134,807,090...134,835,894
Ensembl chr 6:134,807,117...134,835,894
JBrowse link
G Crk v-crk avian sarcoma virus CT10 oncogene homolog increases expression ISO manganese chloride results in increased expression of CRK mRNA CTD PMID:28801915 NCBI chr11:75,570,020...75,599,254
Ensembl chr11:75,570,085...75,597,734
JBrowse link
G Cry1 cryptochrome circadian regulator 1 decreases expression ISO manganese chloride results in decreased expression of CRY1 mRNA CTD PMID:28511934 NCBI chr10:84,967,564...85,020,918
Ensembl chr10:84,967,564...85,020,928
JBrowse link
G Cryaa crystallin, alpha A increases methylation ISO manganese chloride results in increased methylation of CRYAA gene CTD PMID:28801915 NCBI chr17:31,896,905...31,900,704
Ensembl chr17:31,896,781...31,900,707
JBrowse link
G Cryab crystallin, alpha B decreases expression ISO manganese chloride results in decreased expression of CRYAB mRNA CTD PMID:28801915 NCBI chr 9:50,657,251...50,667,936
Ensembl chr 9:50,662,625...50,667,936
JBrowse link
G Cryba4 crystallin, beta A4 increases expression ISO manganese chloride results in increased expression of CRYBA4 mRNA CTD PMID:28801915 NCBI chr 5:112,394,358...112,411,411
Ensembl chr 5:112,394,359...112,400,384
JBrowse link
G Csf2 colony stimulating factor 2 (granulocyte-macrophage) multiple interactions
increases expression
ISO manganese chloride promotes the reaction [SNCA protein results in increased expression of CSF2 mRNA]
manganese chloride results in increased expression of CSF2 mRNA
CTD PMID:28539244 PMID:28801915 NCBI chr11:54,138,096...54,140,725
Ensembl chr11:54,138,097...54,140,493
JBrowse link
G Csf3 colony stimulating factor 3 (granulocyte) increases expression ISO manganese chloride results in increased expression of CSF3 mRNA CTD PMID:28801915 NCBI chr11:98,591,287...98,594,457
Ensembl chr11:98,592,089...98,594,455
JBrowse link
G Cspg4 chondroitin sulfate proteoglycan 4 increases expression
increases methylation
ISO manganese chloride results in increased expression of CSPG4 mRNA
manganese chloride results in increased methylation of CSPG4 gene
CTD PMID:28801915 NCBI chr 9:56,772,388...56,807,154
Ensembl chr 9:56,772,317...56,807,154
JBrowse link
G Csrp3 cysteine and glycine-rich protein 3 increases expression ISO manganese chloride results in increased expression of CSRP3 mRNA CTD PMID:26745496 NCBI chr 7:48,480,146...48,497,799
Ensembl chr 7:48,480,146...48,497,781
JBrowse link
G Cstf2 cleavage stimulation factor, 3' pre-RNA subunit 2 increases expression ISO manganese chloride results in increased expression of CSTF2 mRNA CTD PMID:28801915 NCBI chr  X:132,959,925...132,987,571
Ensembl chr  X:132,959,936...132,987,568
JBrowse link
G Ctnna1 catenin alpha 1 decreases expression ISO manganese chloride results in decreased expression of CTNNA1 mRNA CTD PMID:17175027 NCBI chr18:35,251,955...35,387,829
Ensembl chr18:35,251,912...35,387,832
JBrowse link
G Ctnnb1 catenin beta 1 decreases expression
multiple interactions
ISO manganese chloride results in decreased expression of CTNNB1 mRNA
Lithium Chloride inhibits the reaction [manganese chloride results in decreased expression of CTNNB1 protein]
CTD PMID:17175027 PMID:24464479 NCBI chr 9:120,762,466...120,789,573
Ensembl chr 9:120,758,282...120,789,573
JBrowse link
G Ctnnd1 catenin delta 1 increases expression ISO manganese chloride results in increased expression of CTNND1 mRNA CTD PMID:28801915 NCBI chr 2:84,417,440...84,489,321
Ensembl chr 2:84,430,415...84,481,109
Ensembl chr 2:84,430,415...84,481,109
JBrowse link
G Ctsd cathepsin D increases expression
affects localization
multiple interactions
ISO
EXP
manganese chloride results in increased expression of CTSD protein
manganese chloride affects the localization of CTSD protein
[manganese chloride results in increased abundance of Manganese] which results in decreased activity of CTSD protein
CTD PMID:28378122 PMID:31690173 NCBI chr 7:141,929,647...141,941,564
Ensembl chr 7:141,929,648...141,941,775
JBrowse link
G Ctsw cathepsin W increases expression ISO manganese chloride results in increased expression of CTSW mRNA CTD PMID:28801915 NCBI chr19:5,515,071...5,518,558
Ensembl chr19:5,515,071...5,518,535
JBrowse link
G Cx3cl1 C-X3-C motif chemokine ligand 1 increases expression ISO manganese chloride results in increased expression of CX3CL1 mRNA CTD PMID:28801915 NCBI chr 8:95,498,808...95,509,055
Ensembl chr 8:95,498,637...95,509,055
JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 increases expression
increases methylation
ISO manganese chloride results in increased expression of CXCL1 mRNA
manganese chloride results in increased methylation of CXCL1 gene
CTD PMID:28801915 NCBI chr 5:91,039,104...91,040,980
Ensembl chr 5:91,039,100...91,040,974
JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 increases expression ISO manganese chloride results in increased expression of CXCL10 mRNA CTD PMID:27427241 NCBI chr 5:92,494,497...92,496,748
Ensembl chr 5:92,494,497...92,496,748
JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 decreases expression ISO manganese chloride results in decreased expression of CXCL12 mRNA CTD PMID:28801915 NCBI chr 6:117,145,496...117,158,329
Ensembl chr 6:117,145,496...117,158,328
JBrowse link
G Cxcl14 C-X-C motif chemokine ligand 14 increases expression ISO manganese chloride results in increased expression of CXCL14 mRNA CTD PMID:17175027 NCBI chr13:56,436,456...56,444,624
Ensembl chr13:56,436,456...56,444,364
JBrowse link
G Cxcl15 C-X-C motif chemokine ligand 15 increases expression
affects expression
ISO manganese chloride results in increased expression of CXCL8 mRNA
manganese chloride affects the expression of CXCL8 mRNA
CTD PMID:19815061 PMID:27427241 NCBI chr 5:90,942,393...90,950,926
Ensembl chr 5:90,942,393...90,950,926
JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 increases expression ISO manganese chloride results in increased expression of CXCL2 mRNA CTD PMID:17175027 PMID:28801915 NCBI chr 5:91,051,758...91,053,797
Ensembl chr 5:91,051,730...91,053,797
JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 increases expression ISO manganese chloride results in increased expression of CXCL3 mRNA CTD PMID:28801915 NCBI chr 5:90,933,960...90,935,952
Ensembl chr 5:90,933,962...90,937,459
JBrowse link
G Cxcl5 C-X-C motif chemokine ligand 5 increases expression ISO manganese chloride results in increased expression of CXCL6 mRNA CTD PMID:17175027 NCBI chr 5:90,907,157...90,909,484
Ensembl chr 5:90,907,219...90,909,483
JBrowse link
G Cxxc1 CXXC finger protein 1 decreases expression
increases methylation
ISO manganese chloride results in decreased expression of CXXC1 mRNA
manganese chloride results in increased methylation of CXXC1 gene
CTD PMID:27913844 NCBI chr18:74,349,283...74,354,564
Ensembl chr18:74,349,195...74,354,567
JBrowse link
G Cycs cytochrome c, somatic multiple interactions
affects localization
EXP
ISO
BNIP3 protein affects the reaction [manganese chloride affects the localization of CYCS protein]; Cyclosporine inhibits the reaction [manganese chloride affects the localization of CYCS protein]
SNCA protein inhibits the reaction [manganese chloride affects the localization of CYCS protein]
CTD PMID:19442826 PMID:25416158 NCBI chr 6:50,539,543...50,543,549
Ensembl chr 6:50,539,543...50,543,518
JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 multiple interactions
decreases expression
increases expression
ISO manganese chloride inhibits the reaction [CYP11A1 protein results in increased chemical synthesis of Progesterone]
manganese chloride results in decreased expression of CYP11A1 protein
manganese chloride results in increased expression of CYP11A1 mRNA
CTD PMID:12699903 PMID:25981801 PMID:28801915 NCBI chr 9:57,905,307...57,934,314
Ensembl chr 9:57,913,694...57,934,306
JBrowse link
G Cyp26b1 cytochrome P450, family 26, subfamily b, polypeptide 1 decreases expression ISO manganese chloride results in decreased expression of CYP26B1 mRNA CTD PMID:26745496 NCBI chr 6:84,548,396...84,570,890
Ensembl chr 6:84,548,396...84,570,890
JBrowse link
G Cyria CYFIP related Rac1 interactor A increases expression
increases methylation
ISO manganese chloride results in increased expression of CYRIA mRNA
manganese chloride results in increased methylation of CYRIA gene
CTD PMID:28801915 NCBI chr12:12,312,136...12,430,966
Ensembl chr12:12,312,140...12,430,966
JBrowse link
G Dach2 dachshund family transcription factor 2 increases expression ISO manganese chloride results in increased expression of DACH2 mRNA CTD PMID:17175027 NCBI chr  X:112,207,177...112,746,083
Ensembl chr  X:112,207,207...112,746,083
JBrowse link
G Dact1 dishevelled-binding antagonist of beta-catenin 1 decreases expression ISO manganese chloride results in decreased expression of DACT1 mRNA CTD PMID:28801915 NCBI chr12:71,356,658...71,366,881
Ensembl chr12:71,356,658...71,366,881
JBrowse link
G Dbh dopamine beta hydroxylase increases methylation ISO manganese chloride results in increased methylation of DBH gene CTD PMID:27913844 NCBI chr 2:27,055,519...27,073,216
Ensembl chr 2:27,055,245...27,073,212
JBrowse link
G Dbp D site albumin promoter binding protein increases expression ISO manganese chloride results in increased expression of DBP mRNA CTD PMID:28511934 NCBI chr 7:45,354,658...45,359,579
Ensembl chr 7:45,354,512...45,359,627
JBrowse link
G Dcp1b decapping mRNA 1B increases expression ISO manganese chloride results in increased expression of DCP1B mRNA CTD PMID:28801915 NCBI chr 6:119,152,214...119,198,575
Ensembl chr 6:119,152,214...119,198,577
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 multiple interactions
increases expression
ISO Deferoxamine promotes the reaction [manganese chloride results in increased expression of DDIT3 protein]
[manganese chloride results in increased abundance of Manganese] which results in increased expression of DDIT3 mRNA; SNCA protein promotes the reaction [manganese chloride results in increased expression of DDIT3 mRNA]; SNCA protein promotes the reaction [manganese chloride results in increased expression of DDIT3 protein]
manganese chloride results in increased expression of DDIT3 mRNA; manganese chloride results in increased expression of DDIT3 protein
CTD PMID:23764342 PMID:23934647 PMID:23948121 PMID:25732873 PMID:32574669 NCBI chr10:127,126,662...127,132,160
Ensembl chr10:127,126,643...127,132,157
Ensembl chr10:127,126,643...127,132,157
JBrowse link
G Ddx60 DExD/H box helicase 60 increases expression ISO manganese chloride results in increased expression of DDX60 mRNA CTD PMID:28801915 NCBI chr 8:62,381,155...62,491,278
Ensembl chr 8:62,381,121...62,491,278
JBrowse link
G Defb29 defensin beta 29 increases methylation
increases expression
ISO manganese chloride results in increased methylation of DEFB29 gene
manganese chloride results in increased expression of DEFB29 mRNA
CTD PMID:28801915 NCBI chr 2:152,380,634...152,381,961
Ensembl chr 2:152,380,634...152,382,018
JBrowse link
G Depp1 DEPP1 autophagy regulator increases expression ISO manganese chloride results in increased expression of DEPP1 mRNA CTD PMID:28801915 NCBI chr 6:116,627,645...116,629,808
Ensembl chr 6:116,627,570...116,629,755
JBrowse link
G Dhrs3 dehydrogenase/reductase 3 decreases expression ISO manganese chloride results in decreased expression of DHRS3 mRNA CTD PMID:28801915 NCBI chr 4:144,618,712...144,654,214
Ensembl chr 4:144,619,397...144,654,779
JBrowse link
G Dld dihydrolipoamide dehydrogenase decreases expression ISO manganese chloride results in decreased expression of DLD protein CTD PMID:25981801 NCBI chr12:31,381,561...31,401,470
Ensembl chr12:31,381,276...31,401,452
JBrowse link
G Dlk1 delta like non-canonical Notch ligand 1 decreases expression
increases methylation
ISO manganese chloride results in decreased expression of DLK1 mRNA
manganese chloride results in increased methylation of DLK1 gene
CTD PMID:27913844 NCBI chr12:109,418,411...109,429,262
Ensembl chr12:109,418,749...109,429,262
JBrowse link
G Dll4 delta like canonical Notch ligand 4 increases expression EXP manganese chloride results in increased expression of DLL4 mRNA CTD PMID:17467022 NCBI chr 2:119,156,286...119,166,145
Ensembl chr 2:119,156,265...119,166,443
JBrowse link
G Dmkn dermokine increases expression ISO manganese chloride results in increased expression of DMKN mRNA CTD PMID:28801915 NCBI chr 7:30,463,181...30,480,491
Ensembl chr 7:30,463,181...30,480,488
JBrowse link
G Dnah14 dynein, axonemal, heavy chain 14 decreases expression ISO manganese chloride results in decreased expression of DNAH14 mRNA CTD PMID:17175027 NCBI chr 1:181,404,158...181,642,306
Ensembl chr 1:181,404,124...181,643,339
JBrowse link
G Dnai2 dynein axonemal intermediate chain 2 decreases expression ISO manganese chloride results in decreased expression of DNAI2 mRNA CTD PMID:28801915 NCBI chr11:114,614,634...114,648,715
Ensembl chr11:114,618,234...114,648,715
JBrowse link
G Dnajc12 DnaJ heat shock protein family (Hsp40) member C12 increases expression ISO manganese chloride results in increased expression of DNAJC12 mRNA CTD PMID:28801915 NCBI chr10:63,218,222...63,244,619
Ensembl chr10:63,218,222...63,246,355
JBrowse link
G Dnajc16 DnaJ heat shock protein family (Hsp40) member C16 increases expression ISO manganese chloride results in increased expression of DNAJC16 mRNA CTD PMID:28801915 NCBI chr 4:141,487,498...141,518,255
Ensembl chr 4:141,487,500...141,518,242
JBrowse link
G Dnm1l dynamin 1-like increases expression
multiple interactions
EXP manganese chloride results in increased expression of DNM1L mRNA; manganese chloride results in increased expression of DNM1L protein
6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [Resveratrol inhibits the reaction [manganese chloride promotes the reaction [PPARGC1A protein binds to DNM1L promoter]]]; 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [Resveratrol inhibits the reaction [manganese chloride results in increased expression of DNM1L mRNA]]; 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [Resveratrol inhibits the reaction [manganese chloride results in increased expression of DNM1L protein]]; manganese chloride promotes the reaction [PPARGC1A protein binds to DNM1L promoter]; Resveratrol inhibits the reaction [manganese chloride promotes the reaction [PPARGC1A protein binds to DNM1L promoter]]; Resveratrol inhibits the reaction [manganese chloride results in increased expression of DNM1L mRNA]; Resveratrol inhibits the reaction [manganese chloride results in increased expression of DNM1L protein]
CTD PMID:34738708 NCBI chr16:16,130,092...16,176,863
Ensembl chr16:16,130,094...16,176,823
JBrowse link
G Dnph1 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 decreases expression ISO manganese chloride results in decreased expression of DNPH1 mRNA CTD PMID:17175027 NCBI chr17:46,807,715...46,810,544
Ensembl chr17:46,807,637...46,810,550
JBrowse link
G Doc2a double C2, alpha increases expression ISO manganese chloride results in increased expression of DOC2A mRNA CTD PMID:28801915 NCBI chr 7:126,446,525...126,451,877
Ensembl chr 7:126,446,588...126,451,877
JBrowse link
G Dpep1 dipeptidase 1 decreases expression ISO manganese chloride results in decreased expression of DPEP1 mRNA CTD PMID:28801915 NCBI chr 8:123,913,069...123,928,551
Ensembl chr 8:123,912,981...123,928,551
JBrowse link
G Dpep2 dipeptidase 2 increases expression ISO manganese chloride results in increased expression of DPEP2 mRNA CTD PMID:28801915 NCBI chr 8:106,711,577...106,732,658
Ensembl chr 8:106,711,576...106,718,391
Ensembl chr 8:106,711,576...106,718,391
JBrowse link
G Dph1 diphthamide biosynthesis 1 increases expression ISO manganese chloride results in increased expression of DPH1 mRNA CTD PMID:28801915 NCBI chr11:75,068,469...75,081,309
Ensembl chr11:75,068,469...75,082,067
JBrowse link
G Dpp4 dipeptidylpeptidase 4 increases expression ISO manganese chloride results in increased expression of DPP4 mRNA CTD PMID:17175027 NCBI chr 2:62,160,417...62,242,635
Ensembl chr 2:62,160,417...62,242,575
JBrowse link
G Dpysl3 dihydropyrimidinase-like 3 decreases expression
increases expression
EXP
ISO
manganese chloride results in decreased expression of DPYSL3 mRNA
manganese chloride results in increased expression of DPYSL3 mRNA
CTD PMID:22407947 PMID:25698507 PMID:28801915 NCBI chr18:43,454,044...43,571,354
Ensembl chr18:43,454,049...43,571,351
JBrowse link
G Dr1 down-regulator of transcription 1 decreases expression ISO manganese chloride results in decreased expression of DR1 mRNA CTD PMID:17175027 NCBI chr 5:108,416,763...108,428,387
Ensembl chr 5:108,416,763...108,428,392
JBrowse link
G Drd1 dopamine receptor D1 decreases expression
multiple interactions
increases expression
EXP
ISO
manganese chloride results in decreased expression of DRD1 protein
Melatonin inhibits the reaction [manganese chloride results in decreased expression of DRD1 protein]
manganese chloride results in increased expression of DRD1
[manganese chloride co-treated with Iron deficiency] results in decreased expression of DRD1 protein
CTD PMID:22479410 PMID:23458069 PMID:23604964 PMID:24969583 NCBI chr13:54,205,202...54,209,677
Ensembl chr13:54,205,202...54,209,724
JBrowse link
G Drd2 dopamine receptor D2 multiple interactions
increases expression
decreases expression
ISO
EXP
[manganese chloride co-treated with Iron deficiency] results in increased expression of DRD2 protein; manganese chloride inhibits the reaction [DRD2 protein binds to Spiperone]
manganese chloride results in increased expression of DRD2; manganese chloride results in increased expression of DRD2 protein; manganese chloride results in increased expression of DRD2 protein alternative form
manganese chloride results in decreased expression of DRD2 protein
Melatonin promotes the reaction [manganese chloride results in decreased expression of DRD2 protein]
CTD PMID:21484877 PMID:22479410 PMID:23458069 PMID:24969583 NCBI chr 9:49,251,703...49,319,468
Ensembl chr 9:49,251,927...49,319,477
JBrowse link
G Dscaml1 DS cell adhesion molecule like 1 increases expression ISO manganese chloride results in increased expression of DSCAML1 mRNA CTD PMID:26745496 NCBI chr 9:45,338,735...45,665,011
Ensembl chr 9:45,337,926...45,665,010
JBrowse link
G Dspp dentin sialophosphoprotein increases expression ISO manganese chloride results in increased expression of DSPP mRNA CTD PMID:17175027 NCBI chr 5:104,318,569...104,327,993
Ensembl chr 5:104,318,578...104,327,993
JBrowse link
G Dtx1 deltex 1, E3 ubiquitin ligase increases expression ISO manganese chloride results in increased expression of DTX1 mRNA CTD PMID:28801915 NCBI chr 5:120,818,268...120,850,879
Ensembl chr 5:120,818,267...120,849,992
JBrowse link
G Dusp13b dual specificity phosphatase 13B increases expression ISO manganese chloride results in increased expression of DUSP13B mRNA CTD PMID:28801915 NCBI chr14:21,783,463...21,792,947
Ensembl chr14:21,783,462...21,792,947
JBrowse link
G Dusp2 dual specificity phosphatase 2 increases expression ISO manganese chloride results in increased expression of DUSP2 mRNA CTD PMID:28801915 NCBI chr 2:127,178,079...127,180,297
Ensembl chr 2:127,178,079...127,180,296
JBrowse link
G Dusp4 dual specificity phosphatase 4 increases expression ISO manganese chloride results in increased expression of DUSP4 mRNA CTD PMID:28801915 NCBI chr 8:35,274,448...35,289,106
Ensembl chr 8:35,274,451...35,287,048
JBrowse link
G Dusp5 dual specificity phosphatase 5 increases expression
increases methylation
ISO manganese chloride results in increased expression of DUSP5 mRNA
manganese chloride results in increased methylation of DUSP5 gene
CTD PMID:28801915 NCBI chr19:53,517,576...53,530,240
Ensembl chr19:53,517,540...53,530,862
JBrowse link
G Dusp6 dual specificity phosphatase 6 increases methylation
increases expression
ISO manganese chloride results in increased methylation of DUSP6 gene
manganese chloride results in increased expression of DUSP6 mRNA
CTD PMID:28801915 NCBI chr10:99,098,676...99,103,351
Ensembl chr10:99,099,093...99,103,351
JBrowse link
G Dynlt4 dynein light chain Tctex-type 4 increases expression ISO manganese chloride results in increased expression of DYNLT4 mRNA CTD PMID:28801915 NCBI chr 4:116,981,734...116,985,935
Ensembl chr 4:116,983,991...116,985,935
JBrowse link
G Eaf2 ELL associated factor 2 increases expression
increases methylation
ISO manganese chloride results in increased expression of EAF2 mRNA
manganese chloride results in increased methylation of EAF2 gene
CTD PMID:28801915 NCBI chr16:36,613,246...36,695,275
Ensembl chr16:36,613,246...36,695,365
JBrowse link
G Ebi3 Epstein-Barr virus induced gene 3 increases expression ISO manganese chloride results in increased expression of EBI3 mRNA CTD PMID:28801915 NCBI chr17:56,259,623...56,264,022
Ensembl chr17:56,259,640...56,264,022
JBrowse link
G Ecrg4 ECRG4 augurin precursor decreases expression ISO manganese chloride results in decreased expression of ECRG4 mRNA CTD PMID:28801915 NCBI chr 1:43,769,762...43,781,724
Ensembl chr 1:43,769,762...43,781,738
JBrowse link
G Edn1 endothelin 1 decreases expression ISO manganese chloride results in decreased expression of EDN1 mRNA CTD PMID:28801915 NCBI chr13:42,454,952...42,461,466
Ensembl chr13:42,454,952...42,461,466
JBrowse link
G Egf epidermal growth factor multiple interactions ISO [manganese chloride co-treated with EGF protein] results in increased activity of EGFR protein CTD PMID:2354210 NCBI chr 3:129,471,223...129,548,971
Ensembl chr 3:129,471,214...129,548,965
JBrowse link
G Egfl7 EGF-like domain 7 increases expression EXP manganese chloride results in increased expression of EGFL7 mRNA CTD PMID:17467022 NCBI chr 2:26,471,095...26,482,694
Ensembl chr 2:26,470,026...26,483,132
JBrowse link
G Egfr epidermal growth factor receptor multiple interactions
increases activity
increases expression
ISO [manganese chloride co-treated with EGF protein] results in increased activity of EGFR protein
manganese chloride results in increased activity of EGFR protein
manganese chloride results in increased expression of EGFR mRNA
CTD PMID:2354210 PMID:28801915 NCBI chr11:16,700,153...16,868,158
Ensembl chr11:16,702,203...16,868,158
JBrowse link
G Egln3 egl-9 family hypoxia-inducible factor 3 increases expression ISO manganese chloride results in increased expression of EGLN3 mRNA CTD PMID:28801915 NCBI chr12:54,225,767...54,250,660
Ensembl chr12:54,225,767...54,250,646
JBrowse link
G Egr1 early growth response 1 increases expression ISO
EXP
manganese chloride results in increased expression of EGR1 mRNA CTD PMID:28801915 NCBI chr18:34,994,260...34,998,009
Ensembl chr18:34,992,876...34,998,037
JBrowse link
G Egr2 early growth response 2 increases expression EXP
ISO
manganese chloride results in increased expression of EGR2 mRNA CTD PMID:28801915 NCBI chr10:67,370,334...67,383,354
Ensembl chr10:67,371,305...67,378,018
JBrowse link
G Egr3 early growth response 3 increases expression ISO manganese chloride results in increased expression of EGR3 mRNA CTD PMID:28801915 NCBI chr14:70,314,766...70,320,062
Ensembl chr14:70,314,652...70,320,063
JBrowse link
G Eif1ad eukaryotic translation initiation factor 1A domain containing increases expression ISO manganese chloride results in increased expression of EIF1AD mRNA CTD PMID:28801915 NCBI chr19:5,416,841...5,421,546
Ensembl chr19:5,416,769...5,421,554
JBrowse link
G Eif2a eukaryotic translation initiation factor 2A multiple interactions ISO manganese chloride results in increased expression of and results in increased phosphorylation of EIF2A protein; SNCA protein promotes the reaction [manganese chloride results in increased expression of and results in increased phosphorylation of EIF2A protein] CTD PMID:23934647 NCBI chr 3:58,433,252...58,464,922
Ensembl chr 3:58,433,242...58,464,922
JBrowse link
G Eif2ak2 eukaryotic translation initiation factor 2-alpha kinase 2 multiple interactions ISO [manganese chloride results in increased abundance of Manganese] which results in increased cleavage of EIF2AK2 protein; GW 506033X inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased cleavage of EIF2AK2 protein]; pyrazolanthrone inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased cleavage of EIF2AK2 protein] CTD PMID:32574669 NCBI chr17:79,157,933...79,190,001
Ensembl chr17:79,159,993...79,190,002
JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 multiple interactions
increases phosphorylation
increases expression
ISO [manganese chloride results in increased abundance of Manganese] which results in increased phosphorylation of EIF2AK3 protein; manganese chloride promotes the reaction [EIF2AK3 protein results in increased expression of ATF4 mRNA]; manganese chloride promotes the reaction [EIF2AK3 protein results in increased phosphorylation of EIF2S1 protein]; manganese chloride results in increased expression of and results in increased phosphorylation of EIF2AK3 protein; SNCA protein promotes the reaction [manganese chloride results in increased expression of and results in increased phosphorylation of EIF2AK3 protein]
manganese chloride results in increased phosphorylation of EIF2AK3 protein
manganese chloride results in increased expression of EIF2AK3 protein
CTD PMID:23934647 PMID:23948121 PMID:25732873 PMID:32574669 NCBI chr 6:70,821,468...70,882,225
Ensembl chr 6:70,821,499...70,882,229
JBrowse link
G Eif2s1 eukaryotic translation initiation factor 2, subunit 1 alpha increases phosphorylation
multiple interactions
ISO manganese chloride results in increased phosphorylation of EIF2S1 protein
[manganese chloride results in increased abundance of Manganese] which results in increased phosphorylation of EIF2S1 protein; manganese chloride promotes the reaction [EIF2AK3 protein results in increased phosphorylation of EIF2S1 protein]
CTD PMID:23764342 PMID:23948121 PMID:32574669 NCBI chr12:78,908,846...78,933,784
Ensembl chr12:78,908,593...78,933,784
JBrowse link
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 decreases phosphorylation
multiple interactions
ISO manganese chloride results in decreased phosphorylation of EIF4EBP1 protein
corynoxine B promotes the reaction [manganese chloride results in decreased phosphorylation of EIF4EBP1 protein]
CTD PMID:30578841 NCBI chr 8:27,750,355...27,765,684
Ensembl chr 8:27,750,357...27,766,702
JBrowse link
G Elf1 E74 like ETS transcription factor 1 decreases expression ISO manganese chloride results in decreased expression of ELF1 mRNA CTD PMID:17175027 NCBI chr14:79,718,619...79,819,916
Ensembl chr14:79,718,634...79,819,934
JBrowse link
G Elk3 ELK3, member of ETS oncogene family increases expression EXP manganese chloride results in increased expression of ELK3 mRNA CTD PMID:17467022 NCBI chr10:93,083,277...93,147,021
Ensembl chr10:93,083,276...93,146,997
JBrowse link
G Elmod3 ELMO/CED-12 domain containing 3 increases expression ISO manganese chloride results in increased expression of ELMOD3 mRNA CTD PMID:28801915 NCBI chr 6:72,542,905...72,575,396
Ensembl chr 6:72,542,905...72,575,396
JBrowse link
G Elovl6 ELOVL fatty acid elongase 6 decreases expression ISO manganese chloride results in decreased expression of ELOVL6 mRNA CTD PMID:28801915 NCBI chr 3:129,326,035...129,432,144
Ensembl chr 3:129,326,004...129,432,144
JBrowse link
G Eml2 echinoderm microtubule associated protein like 2 increases expression ISO manganese chloride results in increased expression of EML2 mRNA CTD PMID:17175027 NCBI chr 7:18,910,322...18,940,407
Ensembl chr 7:18,910,346...18,940,407
JBrowse link
G Enc1 ectodermal-neural cortex 1 decreases expression ISO manganese chloride results in decreased expression of ENC1 mRNA CTD PMID:28801915 NCBI chr13:97,377,613...97,389,548
Ensembl chr13:97,377,613...97,389,542
JBrowse link
G Eng endoglin increases expression EXP manganese chloride results in increased expression of ENG mRNA CTD PMID:17467022 NCBI chr 2:32,536,607...32,572,681
Ensembl chr 2:32,536,607...32,572,681
JBrowse link
G Eno2 enolase 2, gamma neuronal increases expression
decreases expression
multiple interactions
ISO
EXP
manganese chloride results in increased expression of ENO2 mRNA
manganese chloride results in decreased expression of ENO2 protein
Melatonin inhibits the reaction [manganese chloride results in decreased expression of ENO2 protein]
CTD PMID:22281203 PMID:24969583 NCBI chr 6:124,737,018...124,746,489
Ensembl chr 6:124,737,016...124,746,636
JBrowse link
G Eomes eomesodermin decreases expression EXP manganese chloride results in decreased expression of EOMES mRNA; manganese chloride results in decreased expression of EOMES protein CTD PMID:25698507 NCBI chr 9:118,307,259...118,315,176
Ensembl chr 9:118,307,280...118,315,200
JBrowse link
G Epas1 endothelial PAS domain protein 1 increases expression EXP manganese chloride results in increased expression of EPAS1 mRNA CTD PMID:17467022 NCBI chr17:87,061,292...87,140,838
Ensembl chr17:87,061,128...87,140,838
JBrowse link
G Epdr1 ependymin related 1 increases expression ISO manganese chloride results in increased expression of EPDR1 mRNA CTD PMID:28801915 NCBI chr13:19,775,878...19,804,000
Ensembl chr13:19,775,876...19,804,097
JBrowse link
G Epha2 Eph receptor A2 increases expression ISO manganese chloride results in increased expression of EPHA2 mRNA CTD PMID:28801915 NCBI chr 4:141,028,532...141,056,695
Ensembl chr 4:141,028,551...141,056,695
JBrowse link
G Epha4 Eph receptor A4 increases methylation
decreases expression
ISO manganese chloride results in increased methylation of EPHA4 gene
manganese chloride results in decreased expression of EPHA4 mRNA
CTD PMID:28801915 NCBI chr 1:77,343,819...77,491,763
Ensembl chr 1:77,343,822...77,491,725
JBrowse link
G Erap1 endoplasmic reticulum aminopeptidase 1 increases expression EXP manganese chloride results in increased expression of ERAP1 mRNA CTD PMID:17467022 NCBI chr13:74,787,692...74,841,321
Ensembl chr13:74,787,687...74,841,320
JBrowse link
G Ercc6l excision repair cross-complementing rodent repair deficiency complementation group 6 like decreases expression ISO manganese chloride results in decreased expression of ERCC6L mRNA CTD PMID:17175027 NCBI chr  X:101,186,426...101,200,697
Ensembl chr  X:101,185,322...101,200,697
JBrowse link
G Ereg epiregulin increases expression ISO manganese chloride results in increased expression of EREG mRNA CTD PMID:17175027 NCBI chr 5:91,222,476...91,241,508
Ensembl chr 5:91,222,481...91,241,505
JBrowse link
G Erich1 glutamate rich 1 increases expression ISO manganese chloride results in increased expression of ERICH1 mRNA CTD PMID:17175027 NCBI chr 8:14,075,051...14,140,393
Ensembl chr 8:14,077,561...14,140,301
JBrowse link
G Ern1 endoplasmic reticulum to nucleus signalling 1 multiple interactions
increases phosphorylation
ISO SNCA protein promotes the reaction [manganese chloride results in increased phosphorylation of ERN1 protein] CTD PMID:23934647 PMID:25732873 NCBI chr11:106,285,474...106,378,701
Ensembl chr11:106,285,476...106,378,678
JBrowse link
G Errfi1 ERBB receptor feedback inhibitor 1 increases expression ISO manganese chloride results in increased expression of ERRFI1 mRNA CTD PMID:28801915 NCBI chr 4:150,938,253...150,953,346
Ensembl chr 4:150,938,376...150,953,349
JBrowse link
G Esr1 estrogen receptor 1 (alpha) decreases expression
multiple interactions
EXP manganese chloride results in decreased expression of ESR1 protein
Estradiol inhibits the reaction [manganese chloride results in decreased expression of ESR1 protein]; Tamoxifen inhibits the reaction [manganese chloride results in decreased expression of ESR1 protein]
CTD PMID:29183790 NCBI chr10:4,561,989...4,955,633
Ensembl chr10:4,561,593...4,955,614
JBrowse link
G Etv3 ets variant 3 increases expression ISO manganese chloride results in increased expression of ETV3 mRNA CTD PMID:28801915 NCBI chr 3:87,432,891...87,447,463
Ensembl chr 3:87,432,714...87,447,463
JBrowse link
G Etv4 ets variant 4 increases expression ISO manganese chloride results in increased expression of ETV4 mRNA CTD PMID:28801915 NCBI chr11:101,660,573...101,677,963
Ensembl chr11:101,660,568...101,676,197
JBrowse link
G Etv5 ets variant 5 increases expression ISO manganese chloride results in increased expression of ETV5 mRNA CTD PMID:28801915 NCBI chr16:22,200,063...22,258,320
Ensembl chr16:22,200,059...22,258,469
JBrowse link
G Eva1c eva-1 homolog C increases expression ISO manganese chloride results in increased expression of EVA1C mRNA CTD PMID:28801915 NCBI chr16:90,623,607...90,701,997
Ensembl chr16:90,623,607...90,701,997
JBrowse link
G Exoc6 exocyst complex component 6 decreases expression ISO manganese chloride results in decreased expression of EXOC6 mRNA CTD PMID:17175027 NCBI chr19:37,525,181...37,672,499
Ensembl chr19:37,509,327...37,672,507
JBrowse link
G Eya4 EYA transcriptional coactivator and phosphatase 4 decreases expression ISO manganese chloride results in decreased expression of EYA4 mRNA CTD PMID:17175027 NCBI chr10:22,978,861...23,226,785
Ensembl chr10:22,978,862...23,226,684
JBrowse link
G F2rl1 F2R like trypsin receptor 1 increases expression ISO manganese chloride results in increased expression of F2RL1 mRNA CTD PMID:28801915 NCBI chr13:95,648,226...95,661,748
Ensembl chr13:95,648,240...95,661,735
JBrowse link
G Fa2h fatty acid 2-hydroxylase increases expression
decreases expression
ISO manganese chloride results in increased expression of FA2H mRNA
manganese chloride results in decreased expression of FA2H mRNA
CTD PMID:26745496 PMID:28801915 NCBI chr 8:112,071,770...112,120,453
Ensembl chr 8:112,071,767...112,120,456
JBrowse link
G Fads2 fatty acid desaturase 2 decreases expression ISO manganese chloride results in decreased expression of FADS2 mRNA CTD PMID:28801915 NCBI chr19:10,040,129...10,078,867
Ensembl chr19:10,040,129...10,079,110
JBrowse link
G Fam107a family with sequence similarity 107, member A decreases expression ISO manganese chloride results in decreased expression of FAM107A mRNA CTD PMID:26745496 NCBI chr14:14,152,166...14,173,503
Ensembl chr14:14,151,750...14,173,499
JBrowse link
G Fam171b family with sequence similarity 171, member B increases expression ISO manganese chloride results in increased expression of FAM171B mRNA CTD PMID:28801915 NCBI chr 2:83,642,889...83,713,878
Ensembl chr 2:83,642,980...83,713,830
JBrowse link
G Fam180a family with sequence similarity 180, member A decreases expression ISO manganese chloride results in decreased expression of FAM180A mRNA CTD PMID:26745496 NCBI chr 6:35,289,678...35,303,076
Ensembl chr 6:35,289,603...35,303,076
JBrowse link
G Fam210a family with sequence similarity 210, member A increases expression ISO manganese chloride results in increased expression of FAM210A mRNA CTD PMID:28801915 NCBI chr18:68,393,248...68,433,404
Ensembl chr18:68,393,258...68,433,404
JBrowse link
G Fam210b family with sequence similarity 210, member B increases expression ISO manganese chloride results in increased expression of FAM210B mRNA CTD PMID:28801915 NCBI chr 2:172,187,444...172,197,669
Ensembl chr 2:172,187,485...172,197,669
JBrowse link
G Fam219a family with sequence similarity 219, member A increases expression ISO manganese chloride results in increased expression of FAM219A mRNA CTD PMID:28801915 NCBI chr 4:41,517,691...41,569,538
Ensembl chr 4:41,517,691...41,569,538
JBrowse link
G Fam227a family with sequence similarity 227, member A increases expression ISO manganese chloride results in increased expression of FAM227A mRNA CTD PMID:28801915 NCBI chr15:79,493,777...79,543,157
Ensembl chr15:79,496,518...79,543,157
JBrowse link
G Fam229b family with sequence similarity 229, member B increases expression ISO manganese chloride results in increased expression of FAM229B mRNA CTD PMID:28801915 NCBI chr10:38,994,800...39,009,936
Ensembl chr10:38,994,800...39,009,910
JBrowse link
G Fancf Fanconi anemia, complementation group F decreases expression ISO manganese chloride results in decreased expression of FANCF mRNA CTD PMID:17175027 NCBI chr 7:51,510,325...51,512,015
Ensembl chr 7:51,510,325...51,512,015
JBrowse link
G Fas Fas cell surface death receptor increases expression ISO manganese chloride results in increased expression of FAS mRNA CTD PMID:28801915 NCBI chr19:34,267,926...34,305,175
Ensembl chr19:34,268,066...34,305,172
JBrowse link
G Fasl Fas ligand increases expression
multiple interactions
ISO manganese chloride results in increased expression of FASLG protein
bafilomycin A1 inhibits the reaction [manganese chloride results in increased expression of FASLG protein]; CA 074 methyl ester inhibits the reaction [manganese chloride results in increased expression of FASLG protein]; pepstatin inhibits the reaction [manganese chloride results in increased expression of FASLG protein]
CTD PMID:21704098 PMID:28378122 NCBI chr 1:161,608,260...161,616,064
Ensembl chr 1:161,608,258...161,616,064
JBrowse link
G Fasn fatty acid synthase decreases expression ISO manganese chloride results in decreased expression of FASN mRNA CTD PMID:28801915 NCBI chr11:120,696,784...120,715,992
Ensembl chr11:120,696,672...120,715,373
JBrowse link
G Fat2 FAT atypical cadherin 2 increases methylation ISO manganese chloride results in increased methylation of FAT2 gene CTD PMID:28801915 NCBI chr11:55,141,435...55,228,331
Ensembl chr11:55,141,435...55,227,390
JBrowse link
G Fat4 FAT atypical cadherin 4 decreases expression ISO manganese chloride results in decreased expression of FAT4 mRNA CTD PMID:28801915 NCBI chr 3:38,939,867...39,066,134
Ensembl chr 3:38,941,089...39,066,134
JBrowse link
G Fbln2 fibulin 2 increases expression ISO manganese chloride results in increased expression of FBLN2 mRNA CTD PMID:28801915 NCBI chr 6:91,189,442...91,249,522
Ensembl chr 6:91,189,437...91,249,522
JBrowse link
G Fbn1 fibrillin 1 increases expression ISO manganese chloride results in increased expression of FBN1 mRNA CTD PMID:28801915 NCBI chr 2:125,142,514...125,348,417
Ensembl chr 2:125,142,514...125,349,913
JBrowse link
G Fbp2 fructose bisphosphatase 2 increases expression ISO manganese chloride results in increased expression of FBP2 mRNA CTD PMID:28801915 NCBI chr13:62,984,698...63,006,214
Ensembl chr13:62,984,691...63,006,236
JBrowse link
G Fbxl2 F-box and leucine-rich repeat protein 2 increases expression ISO manganese chloride results in increased expression of FBXL2 mRNA CTD PMID:28801915 NCBI chr 9:113,787,625...113,855,871
Ensembl chr 9:113,792,705...113,875,259
JBrowse link
G Fbxl4 F-box and leucine-rich repeat protein 4 increases expression ISO manganese chloride results in increased expression of FBXL4 mRNA CTD PMID:28801915 NCBI chr 4:22,357,526...22,434,091
Ensembl chr 4:22,357,543...22,434,091
JBrowse link
G Fcgr1 Fc receptor, IgG, high affinity I decreases expression ISO manganese chloride results in decreased expression of FCGR1A mRNA CTD PMID:26745496 NCBI chr 3:96,190,225...96,201,285
Ensembl chr 3:96,190,225...96,201,285
JBrowse link
G Fcgr4 Fc receptor, IgG, low affinity IV increases expression ISO manganese chloride results in increased expression of FCGR3A mRNA CTD PMID:28801915 NCBI chr 1:170,846,495...170,857,330
Ensembl chr 1:170,846,489...170,857,330
JBrowse link
G Fdps farnesyl diphosphate synthetase decreases expression ISO manganese chloride results in decreased expression of FDPS mRNA CTD PMID:28801915 NCBI chr 3:89,000,895...89,009,274
Ensembl chr 3:89,000,895...89,009,266
JBrowse link
G Fez1 fasciculation and elongation protein zeta 1 increases expression ISO manganese chloride results in increased expression of FEZ1 mRNA CTD PMID:28801915 NCBI chr 9:36,732,694...36,790,220
Ensembl chr 9:36,733,160...36,790,220
JBrowse link
G Fez2 fasciculation and elongation protein zeta 2 increases expression ISO manganese chloride results in increased expression of FEZ2 mRNA CTD PMID:28801915 NCBI chr17:78,676,641...78,725,581
Ensembl chr17:78,676,641...78,725,581
JBrowse link
G Fgf2 fibroblast growth factor 2 decreases expression
increases methylation
EXP
ISO
manganese chloride results in decreased expression of FGF2 mRNA
manganese chloride results in increased methylation of FGF2 gene
CTD PMID:28801915 NCBI chr 3:37,402,616...37,464,255
Ensembl chr 3:37,402,495...37,464,257
JBrowse link
G Fgf20 fibroblast growth factor 20 increases expression ISO manganese chloride results in increased expression of FGF20 mRNA CTD PMID:28986288 NCBI chr 8:40,732,206...40,740,060
Ensembl chr 8:40,732,207...40,761,372
JBrowse link
G Fgfbp1 fibroblast growth factor binding protein 1 decreases expression ISO manganese chloride results in decreased expression of FGFBP1 mRNA CTD PMID:26745496 NCBI chr 5:44,136,200...44,139,173
Ensembl chr 5:44,136,200...44,139,121
JBrowse link
G Fgfr2 fibroblast growth factor receptor 2 decreases expression ISO manganese chloride results in decreased expression of FGFR2 mRNA CTD PMID:28801915 NCBI chr 7:129,764,181...129,868,538
Ensembl chr 7:129,764,181...132,725,079
JBrowse link
G Fhip2b FHF complex subunit HOOK interacting protein 2B increases expression ISO manganese chloride results in increased expression of FHIP2B mRNA CTD PMID:28801915 NCBI chr14:70,820,733...70,837,309
Ensembl chr14:70,820,736...70,837,275
JBrowse link
G Fhl1 four and a half LIM domains 1 decreases expression ISO manganese chloride results in decreased expression of FHL1 mRNA CTD PMID:17175027 NCBI chr  X:55,776,569...55,838,704
Ensembl chr  X:55,777,147...55,838,706
JBrowse link
G Fis1 fission, mitochondrial 1 increases expression EXP manganese chloride results in increased expression of FIS1 protein CTD PMID:34738708 NCBI chr 5:136,982,129...136,995,088
Ensembl chr 5:136,982,129...136,995,088
JBrowse link
G Flcn folliculin increases expression ISO manganese chloride results in increased expression of FLCN mRNA CTD PMID:17175027 NCBI chr11:59,682,234...59,706,138
Ensembl chr11:59,682,234...59,700,842
JBrowse link
G Flrt2 fibronectin leucine rich transmembrane protein 2 increases expression ISO manganese chloride results in increased expression of FLRT2 mRNA CTD PMID:28801915 NCBI chr12:95,658,780...95,751,989
Ensembl chr12:95,659,000...95,751,989
JBrowse link
G Flt1 FMS-like tyrosine kinase 1 increases expression EXP manganese chloride results in increased expression of FLT1 mRNA CTD PMID:17467022 NCBI chr 5:147,498,414...147,663,419
Ensembl chr 5:147,498,414...147,662,821
JBrowse link
G Flvcr2 feline leukemia virus subgroup C cellular receptor 2 decreases expression ISO manganese chloride results in decreased expression of FLVCR2 mRNA CTD PMID:28801915 NCBI chr12:85,793,313...85,860,359
Ensembl chr12:85,793,313...85,860,359
JBrowse link
G Fmo2 flavin containing monooxygenase 2 increases expression ISO manganese chloride results in increased expression of FMO2 mRNA CTD PMID:28801915 NCBI chr 1:162,701,886...162,726,327
Ensembl chr 1:162,701,886...162,726,295
JBrowse link
G Fmo5 flavin containing monooxygenase 5 decreases methylation
increases expression
ISO manganese chloride results in decreased methylation of FMO5 gene
manganese chloride results in increased expression of FMO5 mRNA
CTD PMID:28801915 NCBI chr 3:97,517,248...97,562,603
Ensembl chr 3:97,536,120...97,562,598
JBrowse link
G Fn1 fibronectin 1 multiple interactions
increases expression
ISO [Buthionine Sulfoximine results in decreased abundance of Glutathione] promotes the reaction [manganese chloride results in increased expression of and results in increased secretion of FN1 protein]; [S-ethyl glutathione results in increased abundance of Glutathione] inhibits the reaction [manganese chloride results in increased expression of and results in increased secretion of FN1 protein]; [S-ethyl glutathione results in increased abundance of Glutathione] inhibits the reaction [manganese chloride results in increased expression of FN1 mRNA]; manganese chloride results in increased expression of and results in increased secretion of FN1 protein; Melatonin inhibits the reaction [manganese chloride results in increased expression of and results in increased secretion of FN1 protein]; Melatonin inhibits the reaction [manganese chloride results in increased expression of FN1 mRNA]; phenyl-N-tert-butylnitrone inhibits the reaction [manganese chloride results in increased expression of FN1 mRNA] CTD PMID:19524604 NCBI chr 1:71,624,632...71,692,439
Ensembl chr 1:71,624,679...71,692,359
JBrowse link
G Fos FBJ osteosarcoma oncogene increases expression
decreases expression
ISO
EXP
manganese chloride results in increased expression of FOS protein
manganese chloride results in decreased expression of FOS protein
CTD PMID:9751194 PMID:25698507 NCBI chr12:85,520,664...85,524,048
Ensembl chr12:85,520,664...85,524,047
JBrowse link
G Fosl1 fos-like antigen 1 increases expression ISO manganese chloride results in increased expression of FOSL1 mRNA CTD PMID:28801915 NCBI chr19:5,497,726...5,505,966
Ensembl chr19:5,497,575...5,505,974
JBrowse link
G Foxn4 forkhead box N4 increases expression ISO manganese chloride results in increased expression of FOXN4 mRNA CTD PMID:26745496 NCBI chr 5:114,392,225...114,412,486
Ensembl chr 5:114,392,225...114,411,868
JBrowse link
G Foxp2 forkhead box P2 increases expression ISO manganese chloride results in increased expression of FOXP2 mRNA CTD PMID:17175027 NCBI chr 6:14,901,348...15,441,976
Ensembl chr 6:14,901,348...15,441,976
JBrowse link
G Frem3 Fras1 related extracellular matrix protein 3 increases expression ISO manganese chloride results in increased expression of FREM3 mRNA CTD PMID:28801915 NCBI chr 8:81,337,668...81,422,186
Ensembl chr 8:81,337,709...81,421,985
JBrowse link
G Frmd4a FERM domain containing 4A increases expression ISO manganese chloride results in increased expression of FRMD4A mRNA CTD PMID:28801915 NCBI chr 2:4,022,461...4,618,854
Ensembl chr 2:4,022,528...4,618,854
JBrowse link
G Fscn2 fascin actin-bundling protein 2 decreases expression ISO manganese chloride results in decreased expression of FSCN2 mRNA CTD PMID:28801915 NCBI chr11:120,250,991...120,258,999
Ensembl chr11:120,252,360...120,258,994
JBrowse link
G Fshb follicle stimulating hormone beta decreases expression
multiple interactions
ISO manganese chloride results in decreased expression of FSHB protein
Quercetin inhibits the reaction [manganese chloride results in decreased expression of FSHB protein]
CTD PMID:28040552 NCBI chr 2:106,886,331...106,889,996
Ensembl chr 2:106,886,485...106,890,001
JBrowse link
G Fstl3 follistatin-like 3 increases expression ISO manganese chloride results in increased expression of FSTL3 mRNA CTD PMID:28801915 NCBI chr10:79,613,108...79,618,464
Ensembl chr10:79,613,106...79,618,464
JBrowse link
G Fth1 ferritin heavy polypeptide 1 decreases expression ISO manganese chloride results in decreased expression of FTH1 mRNA; manganese chloride results in decreased expression of FTH1 protein CTD PMID:15893546 PMID:15922012 PMID:16545456 PMID:16568477 NCBI chr19:9,957,964...9,962,475
Ensembl chr19:9,957,962...9,962,462
JBrowse link
G Ftl1 ferritin light polypeptide 1 decreases expression ISO manganese chloride results in decreased expression of FTL mRNA CTD PMID:15893546 NCBI chr 7:45,107,368...45,109,310
Ensembl chr 7:45,107,368...45,109,308
JBrowse link
G Fut1 fucosyltransferase 1 increases expression ISO manganese chloride results in increased expression of FUT1 mRNA CTD PMID:28801915 NCBI chr 7:45,266,862...45,270,483
Ensembl chr 7:45,266,713...45,270,483
JBrowse link
G Fut2 fucosyltransferase 2 increases methylation
decreases expression
ISO manganese chloride results in increased methylation of FUT2 gene
manganese chloride results in decreased expression of FUT2 mRNA
CTD PMID:28801915 NCBI chr 7:45,298,015...45,315,818
Ensembl chr 7:45,298,015...45,315,818
JBrowse link
G Fxyd2 FXYD domain-containing ion transport regulator 2 increases expression ISO manganese chloride results in increased expression of FXYD2 mRNA CTD PMID:17175027 NCBI chr 9:45,311,007...45,321,576
Ensembl chr 9:45,310,967...45,321,576
JBrowse link
G G0s2 G0/G1 switch gene 2 increases expression ISO manganese chloride results in increased expression of G0S2 mRNA CTD PMID:28801915 NCBI chr 1:192,954,468...192,955,496
Ensembl chr 1:192,954,469...192,955,525
JBrowse link
G Gabbr2 gamma-aminobutyric acid type B receptor subunit 2 multiple interactions
decreases expression
ISO [Iron deficiency co-treated with manganese chloride] results in decreased expression of GABBR2 mRNA; [Iron deficiency co-treated with manganese chloride] results in decreased expression of GABBR2 protein
manganese chloride results in decreased expression of GABBR2 mRNA
[manganese chloride results in increased abundance of Manganese] which results in increased expression of GABBR2 protein
CTD PMID:18771689 PMID:32659473 NCBI chr 4:46,662,318...46,991,714
Ensembl chr 4:46,662,305...46,991,873
JBrowse link
G Gabra1 gamma-aminobutyric acid type A receptor subunit alpha 1 multiple interactions
decreases expression
increases expression
ISO [Iron deficiency co-treated with manganese chloride] results in increased expression of GABRA1 protein
manganese chloride results in decreased expression of GABRA1 mRNA
manganese chloride results in increased expression of GABRA1 protein
[manganese chloride results in increased abundance of Manganese] which results in decreased expression of GABRA1 protein
CTD PMID:18771689 PMID:32659473 NCBI chr11:42,021,766...42,073,893
Ensembl chr11:42,021,766...42,073,757
JBrowse link
G Gabrb3 GABRB3, gamma-aminobutyric acid type A receptor subunit beta 3 decreases expression ISO manganese chloride results in decreased expression of GABRB3 mRNA CTD PMID:28801915 NCBI chr 7:57,240,266...57,478,550
Ensembl chr 7:57,069,440...57,478,550
JBrowse link
G Gabrg2 gamma-aminobutyric acid type A receptor, subunit gamma 2 increases expression ISO manganese chloride results in increased expression of GABRG2 mRNA CTD PMID:17175027 NCBI chr11:41,801,017...41,891,684
Ensembl chr11:41,801,030...41,891,684
JBrowse link
G Gad1 glutamate decarboxylase 1 decreases expression ISO manganese chloride results in decreased expression of GAD1 mRNA CTD PMID:12106697 NCBI chr 2:70,392,109...70,432,358
Ensembl chr 2:70,383,416...70,432,358
JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible 45 alpha decreases expression ISO manganese chloride results in decreased expression of GADD45A mRNA CTD PMID:28801915 NCBI chr 6:67,012,080...67,014,391
Ensembl chr 6:67,012,080...67,014,441
JBrowse link
G Gal galanin and GMAP prepropeptide increases expression ISO manganese chloride results in increased expression of GAL mRNA CTD PMID:17175027 NCBI chr19:3,459,915...3,464,544
Ensembl chr19:3,459,915...3,464,544
JBrowse link
G Gale galactose-4-epimerase, UDP decreases expression ISO manganese chloride results in decreased expression of GALE mRNA CTD PMID:28801915 NCBI chr 4:135,690,550...135,695,489
Ensembl chr 4:135,691,038...135,695,489
JBrowse link
G Garin1b golgi associated RAB2 interactor 1B increases expression ISO manganese chloride results in increased expression of GARIN1B mRNA CTD PMID:28801915 NCBI chr 6:29,313,468...29,336,021
Ensembl chr 6:29,319,139...29,336,018
JBrowse link
G Gbe1 1,4-alpha-glucan branching enzyme 1 decreases expression
increases methylation
ISO manganese chloride results in decreased expression of GBE1 mRNA
manganese chloride results in increased methylation of GBE1 gene
CTD PMID:27913844 NCBI chr16:70,110,837...70,366,608
Ensembl chr16:70,110,837...70,366,604
JBrowse link
G Gbp5 guanylate binding protein 5 increases methylation
increases expression
ISO manganese chloride results in increased methylation of GBP5 gene
manganese chloride results in increased expression of GBP5 mRNA
CTD PMID:28801915 NCBI chr 3:142,202,695...142,228,105
Ensembl chr 3:142,199,739...142,228,105
JBrowse link
G Gcdh glutaryl-Coenzyme A dehydrogenase decreases expression ISO manganese chloride results in decreased expression of GCDH mRNA CTD PMID:22281203 NCBI chr 8:85,613,016...85,629,378
Ensembl chr 8:85,613,022...85,620,550
JBrowse link
G Gcfc2 GC-rich sequence DNA binding factor 2 decreases expression ISO manganese chloride results in decreased expression of GCFC2 mRNA CTD PMID:17175027 NCBI chr 6:81,887,543...81,936,079
Ensembl chr 6:81,900,650...81,936,896
JBrowse link
G Gcgr glucagon receptor decreases expression
increases methylation
ISO manganese chloride results in decreased expression of GCGR mRNA
manganese chloride results in increased methylation of GCGR gene
CTD PMID:28801915 NCBI chr11:120,420,011...120,429,815
Ensembl chr11:120,421,525...120,429,812
JBrowse link
G Gch1 GTP cyclohydrolase 1 decreases expression ISO manganese chloride results in decreased expression of GCH1 mRNA CTD PMID:28801915 NCBI chr14:47,391,352...47,426,870
Ensembl chr14:47,391,352...47,426,870
JBrowse link
G Gclm glutamate-cysteine ligase, modifier subunit multiple interactions ISO [manganese chloride results in increased abundance of Manganese] which results in decreased expression of GCLM mRNA CTD PMID:38503349 NCBI chr 3:122,039,206...122,060,864
Ensembl chr 3:122,039,206...122,064,381
JBrowse link
G Gdap2 ganglioside-induced differentiation-associated-protein 2 increases expression ISO manganese chloride results in increased expression of GDAP2 mRNA CTD PMID:17175027 NCBI chr 3:100,069,843...100,117,909
Ensembl chr 3:100,069,697...100,114,297
JBrowse link
G Gdf15 growth differentiation factor 15 increases expression ISO manganese chloride results in increased expression of GDF15 mRNA CTD PMID:17175027 NCBI chr 8:71,082,043...71,085,106
Ensembl chr 8:71,082,043...71,085,106
JBrowse link
G Gdnf glial cell line derived neurotrophic factor increases methylation ISO manganese chloride results in increased methylation of GDNF gene CTD PMID:27913844 NCBI chr15:7,839,529...7,867,061
Ensembl chr15:7,840,327...7,867,056
JBrowse link
G Gfap glial fibrillary acidic protein decreases expression
increases expression
multiple interactions
ISO
EXP
manganese chloride results in decreased expression of GFAP protein
manganese chloride results in increased expression of GFAP protein
Melatonin inhibits the reaction [manganese chloride results in increased expression of GFAP protein]
CTD PMID:12009774 PMID:12106697 PMID:24060432 PMID:24969583 PMID:25288107 More... NCBI chr11:102,778,162...102,791,368
Ensembl chr11:102,778,162...102,791,738
JBrowse link
G Gja1 gap junction protein, alpha 1 decreases expression ISO manganese chloride results in decreased expression of GJA1 mRNA CTD PMID:28801915 NCBI chr10:56,253,297...56,266,519
Ensembl chr10:56,253,426...56,278,609
JBrowse link
G Gja5 gap junction protein, alpha 5 decreases expression ISO manganese chloride results in decreased expression of GJA5 mRNA CTD PMID:26745496 NCBI chr 3:96,939,718...96,960,950
Ensembl chr 3:96,812,009...96,984,732
JBrowse link
G Gja8 gap junction protein, alpha 8 increases expression ISO manganese chloride results in increased expression of GJA8 mRNA CTD PMID:28801915 NCBI chr 3:96,820,882...96,833,367
Ensembl chr 3:96,820,882...96,833,336
JBrowse link
G Gjb5 gap junction protein, beta 5 increases expression ISO manganese chloride results in increased expression of GJB5 mRNA CTD PMID:28801915 NCBI chr 4:127,248,600...127,251,957
Ensembl chr 4:127,248,602...127,251,974
JBrowse link
G Gkn3 gastrokine 3 decreases expression ISO manganese chloride results in decreased expression of GKN3 mRNA CTD PMID:28801915 NCBI chr 6:87,360,301...87,365,917
Ensembl chr 6:87,360,238...87,365,917
JBrowse link
G Gldn gliomedin decreases expression ISO manganese chloride results in decreased expression of GLDN mRNA CTD PMID:26745496 NCBI chr 9:54,193,770...54,249,061
Ensembl chr 9:54,193,770...54,249,070
JBrowse link
G Glis1 GLIS family zinc finger 1 decreases expression ISO manganese chloride results in decreased expression of GLIS1 mRNA CTD PMID:28801915 NCBI chr 4:107,283,840...107,492,258
Ensembl chr 4:107,291,788...107,492,258
JBrowse link
G Glis2 GLIS family zinc finger 2 increases expression ISO manganese chloride results in increased expression of GLIS2 mRNA CTD PMID:28801915 NCBI chr16:4,412,217...4,443,076
Ensembl chr16:4,412,577...4,442,788
JBrowse link
G Glt8d2 glycosyltransferase 8 domain containing 2 increases expression ISO manganese chloride results in increased expression of GLT8D2 mRNA CTD PMID:28801915 NCBI chr10:82,486,262...82,529,846
Ensembl chr10:82,486,267...82,526,484
JBrowse link
G Glul glutamate-ammonia ligase decreases expression
multiple interactions
ISO manganese chloride results in decreased expression of GLUL mRNA; manganese chloride results in decreased expression of GLUL protein
Riluzole inhibits the reaction [manganese chloride results in decreased expression of and results in decreased activity of GLUL protein]; Riluzole inhibits the reaction [manganese chloride results in decreased expression of GLUL mRNA]
CTD PMID:19615351 NCBI chr 1:153,775,692...153,785,469
Ensembl chr 1:153,775,690...153,785,469
JBrowse link
G Gm4984 predicted pseudogene 4984 increases expression ISO manganese chloride results in increased expression of MPC1L mRNA CTD PMID:28801915 NCBI chr  X:12,518,492...12,519,064
Ensembl chr  X:12,518,542...12,518,901
JBrowse link
G Gnb4 guanine nucleotide binding protein (G protein), beta 4 increases expression ISO manganese chloride results in increased expression of GNB4 mRNA CTD PMID:28801915 NCBI chr 3:32,632,736...32,670,813
Ensembl chr 3:32,634,481...32,670,734
JBrowse link
G Gnrh1 gonadotropin releasing hormone 1 increases expression
multiple interactions
increases secretion
ISO manganese chloride results in increased expression of GNRH1 mRNA
1H-(1,2,4)oxadiazolo(4,3-a)quinoxalin-1-one inhibits the reaction [manganese chloride results in increased secretion of GNRH1 protein]; [manganese chloride co-treated with Calcium Chloride] results in increased secretion of GNRH1 protein; [manganese chloride results in increased chemical synthesis of Cyclic GMP] which results in increased secretion of GNRH1 protein; Bicuculline promotes the reaction [manganese chloride results in increased secretion of GNRH1 protein]; Dopamine affects the reaction [manganese chloride results in increased secretion of GNRH1 protein]; gamma-Aminobutyric Acid inhibits the reaction [manganese chloride results in increased secretion of GNRH1 protein]; Haloperidol inhibits the reaction [manganese chloride results in increased secretion of GNRH1 protein]; KT 5823 inhibits the reaction [manganese chloride results in increased secretion of GNRH1 protein]; Methylene Blue inhibits the reaction [manganese chloride results in increased secretion of GNRH1 protein]
CTD PMID:17110411 PMID:17290048 PMID:18603625 PMID:21402727 NCBI chr14:67,982,717...67,986,889
Ensembl chr14:67,982,630...67,986,888
JBrowse link
G Gpnmb glycoprotein (transmembrane) nmb increases expression ISO manganese chloride results in increased expression of GPNMB mRNA CTD PMID:28801915 NCBI chr 6:49,013,449...49,044,413
Ensembl chr 6:49,013,480...49,047,863
JBrowse link
G Gpr18 G protein-coupled receptor 18 decreases expression ISO manganese chloride results in decreased expression of GPR18 mRNA CTD PMID:26745496 NCBI chr14:122,148,846...122,153,300
Ensembl chr14:122,148,665...122,153,193
JBrowse link
G Gpr34 G protein-coupled receptor 34 decreases expression ISO manganese chloride results in decreased expression of GPR34 mRNA CTD PMID:26745496 NCBI chr  X:13,489,777...13,507,098
Ensembl chr  X:13,498,328...13,507,097
JBrowse link
G Gpx1 glutathione peroxidase 1 multiple interactions
decreases expression
increases activity
EXP
ISO
Melatonin affects the reaction [manganese chloride results in decreased expression of GPX1 protein]
manganese chloride results in increased activity of GPX1 protein
[Cadmium Chloride co-treated with lead acetate co-treated with manganese chloride] results in increased activity of GPX1 protein
CTD PMID:24969583 PMID:25288107 PMID:27599793 NCBI chr 9:108,216,279...108,217,541
Ensembl chr 9:108,216,102...108,217,542
JBrowse link
G Grik3 glutamate receptor, ionotropic, kainate 3 increases methylation
decreases expression
ISO manganese chloride results in increased methylation of GRIK3 gene
manganese chloride results in decreased expression of GRIK3 mRNA
CTD PMID:27913844 PMID:28801915 NCBI chr 4:125,384,025...125,607,966
Ensembl chr 4:125,384,493...125,607,966
JBrowse link
G Grin1 glutamate receptor, ionotropic, NMDA1 (zeta 1) decreases expression ISO manganese chloride results in decreased expression of GRIN1 mRNA; manganese chloride results in decreased expression of GRIN1 protein CTD PMID:20175136 NCBI chr 2:25,181,189...25,209,199
Ensembl chr 2:25,181,193...25,209,199
JBrowse link
G Grin2a glutamate receptor, ionotropic, NMDA2A (epsilon 1) decreases expression ISO manganese chloride results in decreased expression of GRIN2A mRNA; manganese chloride results in decreased expression of GRIN2A protein CTD PMID:20175136 NCBI chr16:9,385,765...9,813,744
Ensembl chr16:9,385,762...9,813,424
JBrowse link
G Grin2b glutamate receptor, ionotropic, NMDA2B (epsilon 2) decreases expression ISO manganese chloride results in decreased expression of GRIN2B mRNA; manganese chloride results in decreased expression of GRIN2B protein CTD PMID:20175136 NCBI chr 6:135,690,219...136,150,658
Ensembl chr 6:135,690,231...136,150,509
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta multiple interactions
increases activity
decreases phosphorylation
ISO 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [manganese chloride results in decreased phosphorylation of GSK3B protein]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [manganese chloride results in increased activity of GSK3B protein]; [Lithium Chloride results in decreased activity of GSK3B protein] inhibits the reaction [manganese chloride results in increased phosphorylation of MAPT protein]; GSK3B protein affects the reaction [manganese chloride results in increased phosphorylation of MAPT protein]; Lithium Chloride inhibits the reaction [manganese chloride results in decreased phosphorylation of and results in increased activity of GSK3B protein]; manganese chloride results in decreased phosphorylation of and results in increased activity of GSK3B protein CTD PMID:20937724 PMID:24464479 NCBI chr16:37,909,363...38,066,446
Ensembl chr16:37,909,363...38,066,446
JBrowse link
G Gskip GSK3B interacting protein increases expression ISO manganese chloride results in increased expression of GSKIP mRNA CTD PMID:28801915 NCBI chr12:105,651,611...105,669,317
Ensembl chr12:105,651,088...105,669,282
JBrowse link
G Gspt2 G1 to S phase transition 2 decreases expression ISO manganese chloride results in decreased expression of GSPT2 mRNA CTD PMID:28801915 NCBI chr  X:93,679,675...93,682,168
Ensembl chr  X:93,679,675...93,686,850
JBrowse link
G Gsr glutathione reductase decreases expression
multiple interactions
ISO
EXP
manganese chloride results in decreased expression of GSR mRNA
manganese chloride results in decreased expression of GSR protein
[manganese chloride results in increased abundance of Manganese] which results in decreased activity of GSR protein; Melatonin affects the reaction [manganese chloride results in decreased expression of GSR protein]; Melatonin inhibits the reaction [manganese chloride results in decreased expression of GSR protein]
CTD PMID:17175027 PMID:24969583 PMID:25288107 PMID:32445656 NCBI chr 8:34,143,266...34,188,190
Ensembl chr 8:34,142,551...34,188,191
JBrowse link
G Gsto1 glutathione S-transferase omega 1 multiple interactions ISO [manganese chloride results in increased abundance of Manganese] which results in decreased expression of GSTO1 mRNA; [manganese chloride results in increased abundance of Manganese] which results in decreased expression of GSTO1 protein CTD PMID:38129942 NCBI chr19:47,843,412...47,853,229
Ensembl chr19:47,843,409...47,853,229
JBrowse link
G Gtf2h1 general transcription factor II H, polypeptide 1 decreases expression ISO manganese chloride results in decreased expression of GTF2H1 mRNA CTD PMID:17175027 NCBI chr 7:46,445,518...46,473,224
Ensembl chr 7:46,445,527...46,473,224
JBrowse link
G H1f1 H1.1 linker histone, cluster member decreases expression ISO manganese chloride results in decreased expression of H1F1 mRNA CTD PMID:28801915 NCBI chr13:23,947,651...23,948,395
Ensembl chr13:23,947,649...23,948,389
JBrowse link
G H1f2 H1.2 linker histone, cluster member decreases expression ISO manganese chloride results in decreased expression of H1F2 mRNA CTD PMID:28801915 NCBI chr13:23,922,790...23,923,514
Ensembl chr13:23,922,791...23,924,350
JBrowse link
G H2bc27 H2B clustered histone 27 decreases expression ISO manganese chloride results in decreased expression of H2BU1 mRNA CTD PMID:28801915 NCBI chr11:58,839,737...58,840,198
Ensembl chr11:58,839,746...58,840,359
JBrowse link
G H2bc4 H2B clustered histone 4 decreases expression ISO manganese chloride results in decreased expression of HIST1H2BC mRNA CTD PMID:28801915 NCBI chr13:23,868,182...23,876,805
Ensembl chr13:23,868,182...23,876,891
JBrowse link
G H2bc8 H2B clustered histone 8 decreases expression ISO manganese chloride results in decreased expression of H2BC8 mRNA CTD PMID:28801915 NCBI chr13:23,755,574...23,756,037
Ensembl chr13:23,755,570...23,756,187
JBrowse link
G H3c1 H3 clustered histone 1 decreases expression ISO manganese chloride results in decreased expression of H3C1 mRNA CTD PMID:28801915 NCBI chr13:23,945,868...23,946,369
Ensembl chr13:23,945,836...23,946,369
JBrowse link
G Hamp hepcidin antimicrobial peptide decreases expression
multiple interactions
ISO
EXP
manganese chloride results in decreased expression of HAMP mRNA
[manganese chloride results in increased abundance of Manganese] promotes the reaction [Ethanol results in decreased expression of HAMP protein]; [manganese chloride results in increased abundance of Manganese] which results in decreased expression of HAMP protein
CTD PMID:20635692 PMID:34590183 NCBI chr 7:30,641,793...30,643,454
Ensembl chr 7:30,641,793...30,643,457
JBrowse link
G Hapln3 hyaluronan and proteoglycan link protein 3 increases expression ISO manganese chloride results in increased expression of HAPLN3 mRNA CTD PMID:28801915 NCBI chr 7:78,766,775...78,783,100
Ensembl chr 7:78,764,850...78,780,766
JBrowse link
G Hat1 histone aminotransferase 1 decreases expression ISO manganese chloride results in decreased expression of HAT1 protein CTD PMID:29155171 NCBI chr 2:71,219,604...71,271,966
Ensembl chr 2:71,219,302...71,271,966
JBrowse link
G Hc hemolytic complement decreases expression ISO manganese chloride results in decreased expression of C5 mRNA CTD PMID:28801915 NCBI chr 2:34,873,341...34,958,518
Ensembl chr 2:34,873,343...34,951,450
JBrowse link
G Hdac1 histone deacetylase 1 multiple interactions ISO [manganese chloride results in increased abundance of Manganese] promotes the reaction [YY1 protein binds to HDAC1 protein]; Hesperidin inhibits the reaction [[manganese chloride results in increased abundance of Manganese] promotes the reaction [YY1 protein binds to HDAC1 protein]] CTD PMID:34800614 NCBI chr 4:129,409,897...129,436,516
Ensembl chr 4:129,409,897...129,436,506
JBrowse link
G Hdac2 histone deacetylase 2 increases expression ISO manganese chloride results in increased expression of HDAC2 mRNA CTD PMID:29155171 NCBI chr10:36,850,293...36,877,885
Ensembl chr10:36,850,540...36,877,885
JBrowse link
G Hdac3 histone deacetylase 3 increases expression
multiple interactions
ISO manganese chloride results in increased expression of HDAC3 mRNA; manganese chloride results in increased expression of HDAC3 protein
[manganese chloride results in increased abundance of Manganese] promotes the reaction [YY1 protein binds to HDAC3 protein]; silmitasertib inhibits the reaction [[manganese chloride results in increased abundance of Manganese] promotes the reaction [YY1 protein binds to HDAC3 protein]]
CTD PMID:29155171 PMID:34800614 NCBI chr18:38,070,024...38,088,073
Ensembl chr18:38,068,897...38,088,069
JBrowse link
G Hdac4 histone deacetylase 4 increases expression ISO manganese chloride results in increased expression of HDAC4 mRNA; manganese chloride results in increased expression of HDAC4 protein CTD PMID:29155171 NCBI chr 1:91,856,501...92,123,424
Ensembl chr 1:91,856,501...92,123,421
JBrowse link
G Hdgfl3 HDGF like 3 increases expression ISO manganese chloride results in increased expression of HDGFL3 mRNA CTD PMID:28801915 NCBI chr 7:81,531,004...81,587,227
Ensembl chr 7:81,530,999...81,584,221
JBrowse link
G Heatr3 HEAT repeat containing 3 increases expression ISO manganese chloride results in increased expression of HEATR3 mRNA CTD PMID:28801915 NCBI chr 8:88,864,453...88,901,656
Ensembl chr 8:88,864,483...88,898,655
JBrowse link
G Heph hephaestin increases expression ISO manganese chloride results in increased expression of HEPH mRNA CTD PMID:17175027 NCBI chr  X:95,499,042...95,618,091
Ensembl chr  X:95,498,965...95,618,091
JBrowse link
G Hexd hexosaminidase D multiple interactions EXP [manganese chloride results in increased abundance of Manganese] which results in decreased expression of HEXD mRNA CTD PMID:35690225 NCBI chr11:121,095,187...121,113,485
Ensembl chr11:121,095,259...121,113,481
JBrowse link
G Hey1 hairy/enhancer-of-split related with YRPW motif 1 increases expression ISO manganese chloride results in increased expression of HEY1 mRNA CTD PMID:28801915 NCBI chr 3:8,728,419...8,732,098
Ensembl chr 3:8,728,419...8,732,316
JBrowse link
G Hfe homeostatic iron regulator multiple interactions
decreases response to substance
EXP HFE gene mutant form inhibits the reaction [manganese chloride results in decreased activity of SOD1 protein]
HFE gene mutant form results in decreased susceptibility to manganese chloride
CTD PMID:25874029 NCBI chr13:23,886,017...23,894,837
Ensembl chr13:23,886,017...23,894,837
JBrowse link
G Hif1a hypoxia inducible factor 1, alpha subunit increases expression
multiple interactions
decreases hydroxylation
increases stability
decreases degradation
decreases expression
ISO
EXP
manganese chloride results in increased expression of HIF1A mRNA; manganese chloride results in increased expression of HIF1A protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [manganese chloride results in increased expression of and results in increased activity of HIF1A protein]; [manganese chloride results in decreased activity of P4HTM protein] which results in decreased degradation of HIF1A protein; [manganese chloride results in decreased activity of P4HTM protein] which results in decreased hydroxylation of HIF1A protein; Ascorbic Acid inhibits the reaction [manganese chloride results in decreased hydroxylation of HIF1A protein]; Ascorbic Acid inhibits the reaction [manganese chloride results in increased stability of HIF1A protein]; HIF1A mutant form inhibits the reaction [manganese chloride results in increased secretion of VEGFA protein]; Iron inhibits the reaction [manganese chloride results in increased expression of HIF1A protein]; manganese chloride inhibits the reaction [[benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with Ketoglutaric Acids co-treated with Ascorbic Acid co-treated with ferrous chloride] promotes the reaction [VHL protein binds to HIF1A protein]]; manganese chloride results in increased expression of and results in increased activity of and results in increased stability of HIF1A protein; pyrazolanthrone inhibits the reaction [manganese chloride results in increased expression of and results in increased activity of and results in increased stability of HIF1A protein]; SB 203580 inhibits the reaction [manganese chloride results in increased expression of and results in increased activity of and results in increased stability of HIF1A protein]; SB 203580 inhibits the reaction [manganese chloride results in increased expression of and results in increased activity of HIF1A protein]; VHL protein affects the reaction [manganese chloride results in increased expression of HIF1A protein]
manganese chloride results in decreased degradation of HIF1A protein
manganese chloride results in decreased expression of HIF1A mRNA
[[manganese chloride results in increased abundance of Manganese] which co-treated with Ethanol] results in increased expression of HIF1A protein; [manganese chloride results in increased abundance of Manganese] which results in increased expression of HIF1A protein
CTD PMID:17175027 PMID:17467022 PMID:19074761 PMID:19263519 PMID:20152896 More... NCBI chr12:73,948,186...73,994,304
Ensembl chr12:73,948,149...73,994,304
JBrowse link
G Hif1an hypoxia-inducible factor 1, alpha subunit inhibitor decreases expression ISO manganese chloride results in decreased expression of HIF1AN mRNA CTD PMID:17175027 NCBI chr19:44,551,293...44,564,713
Ensembl chr19:44,551,289...44,564,713
JBrowse link
G Hilpda hypoxia inducible lipid droplet associated increases expression ISO manganese chloride results in increased expression of HILPDA mRNA CTD PMID:22281203 NCBI chr 6:29,272,487...29,275,448
Ensembl chr 6:29,272,487...29,275,445
JBrowse link
G Hipk3 homeodomain interacting protein kinase 3 decreases expression ISO manganese chloride results in decreased expression of HIPK3 mRNA CTD PMID:28801915 NCBI chr 2:104,256,826...104,324,834
Ensembl chr 2:104,256,826...104,324,791
JBrowse link
G Hmbox1 homeobox containing 1 decreases expression ISO manganese chloride results in decreased expression of HMBOX1 mRNA CTD PMID:28801915 NCBI chr14:65,049,049...65,187,354
Ensembl chr14:65,049,049...65,187,320
JBrowse link
G Hmcn2 hemicentin 2 increases expression ISO manganese chloride results in increased expression of HMCN2 mRNA CTD PMID:28801915 NCBI chr 2:31,204,273...31,350,751
Ensembl chr 2:31,204,427...31,350,750
JBrowse link
G Hmgb1 high mobility group box 1 increases expression
multiple interactions
ISO manganese chloride results in increased expression of HMGB1 mRNA
corynoxine B affects the reaction [manganese chloride affects the reaction [HMGB1 protein binds to BECN1 protein]]; corynoxine B inhibits the reaction [manganese chloride promotes the reaction [HMGB1 protein binds to SNCA protein]]; manganese chloride affects the reaction [HMGB1 protein binds to BECN1 protein]; manganese chloride promotes the reaction [HMGB1 protein binds to SNCA protein]; manganese chloride results in increased expression of and affects the localization of HMGB1 protein
CTD PMID:30578841 NCBI chr 5:148,983,512...148,989,867
Ensembl chr 5:148,983,512...149,121,299
JBrowse link
G Hmgcs2 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2 decreases expression ISO manganese chloride results in decreased expression of HMGCS2 mRNA CTD PMID:26745496 NCBI chr 3:98,187,747...98,218,054
Ensembl chr 3:98,187,751...98,218,054
JBrowse link
G Hmox1 heme oxygenase 1 affects response to substance
multiple interactions
increases expression
EXP
ISO
HMOX1 protein affects the susceptibility to manganese chloride
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [manganese chloride results in increased expression of HMOX1 protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [manganese chloride results in increased expression of HMOX1 protein]; [Acetylcysteine affects the abundance of Reactive Oxygen Species] inhibits the reaction [manganese chloride promotes the reaction [NFE2L2 protein binds to HMOX1 promoter]]; [Acetylcysteine affects the abundance of Reactive Oxygen Species] inhibits the reaction [manganese chloride results in increased expression of HMOX1 protein]; [manganese chloride results in increased abundance of Manganese] which results in increased expression of HMOX1 protein; anacardic acid promotes the reaction [manganese chloride results in increased expression of HMOX1 mRNA]; GW 506033X promotes the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased expression of HMOX1 protein]; lactacystin promotes the reaction [manganese chloride promotes the reaction [NFE2L2 protein binds to HMOX1 promoter]]; lactacystin promotes the reaction [manganese chloride results in increased expression of HMOX1 protein]; manganese chloride promotes the reaction [[NFE2L2 protein binds to HMOX1 promoter] which results in increased expression of HMOX1 mRNA]; manganese chloride promotes the reaction [NFE2L2 protein binds to HMOX1 promoter]; SB 203580 inhibits the reaction [manganese chloride results in increased expression of HMOX1 protein]; tin protoporphyrin IX inhibits the reaction [manganese chloride results in increased expression of HMOX1 protein]; trichostatin A promotes the reaction [manganese chloride results in increased expression of HMOX1 mRNA]; trichostatin A promotes the reaction [manganese chloride results in increased expression of HMOX1 protein]
HMOX1 protein inhibits the reaction [manganese chloride results in increased abundance of Hydrogen Peroxide]; manganese chloride promotes the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of HMOX1 mRNA]; manganese chloride promotes the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of HMOX1 protein]; Melatonin inhibits the reaction [manganese chloride results in increased expression of HMOX1 protein]
manganese chloride results in increased expression of HMOX1 mRNA; manganese chloride results in increased expression of HMOX1 protein
[manganese chloride results in increased abundance of Manganese] which results in increased expression of HMOX1 mRNA
CTD PMID:21107535 PMID:21384399 PMID:21963524 PMID:22281203 PMID:25288107 More... NCBI chr 8:75,820,246...75,827,221
Ensembl chr 8:75,820,249...75,827,217
JBrowse link
G Hoxb9 homeobox B9 decreases expression ISO manganese chloride results in decreased expression of HOXB9 mRNA CTD PMID:17175027 NCBI chr11:96,162,156...96,167,421
Ensembl chr11:96,162,283...96,167,421
JBrowse link
G Hoxd4 homeobox D4 increases expression ISO manganese chloride results in increased expression of HOXD4 mRNA CTD PMID:28801915 NCBI chr 2:74,552,322...74,559,504
Ensembl chr 2:74,542,273...74,559,504
JBrowse link
G Hpx hemopexin decreases expression ISO manganese chloride results in decreased expression of HPX mRNA CTD PMID:28801915 NCBI chr 7:105,240,818...105,249,323
Ensembl chr 7:105,240,820...105,249,344
JBrowse link
G Hrh1 histamine receptor H1 decreases methylation ISO manganese chloride results in decreased methylation of HRH1 gene CTD PMID:27913844 NCBI chr 6:114,374,897...114,459,432
Ensembl chr 6:114,374,897...114,460,257
JBrowse link
G Hrk harakiri, BCL2 interacting protein (contains only BH3 domain) increases expression
decreases methylation
ISO manganese chloride results in increased expression of HRK mRNA
manganese chloride results in decreased methylation of HRK gene
CTD PMID:28801915 NCBI chr 5:118,307,829...118,327,543
Ensembl chr 5:118,302,713...118,327,543
JBrowse link
G Hsd11b1 hydroxysteroid 11-beta dehydrogenase 1 increases expression ISO manganese chloride results in increased expression of HSD11B1 mRNA CTD PMID:28801915 NCBI chr 1:192,903,917...192,946,345
Ensembl chr 1:192,903,942...192,946,383
JBrowse link
G Hsp90b1 heat shock protein 90, beta (Grp94), member 1 multiple interactions
increases expression
ISO SNCA protein promotes the reaction [manganese chloride results in increased expression of HSP90B1 mRNA]; SNCA protein promotes the reaction [manganese chloride results in increased expression of HSP90B1 protein]
manganese chloride results in increased expression of HSP90B1 mRNA; manganese chloride results in increased expression of HSP90B1 protein
CTD PMID:23934647 PMID:23948121 NCBI chr10:86,526,705...86,541,308
Ensembl chr10:86,526,073...86,541,373
JBrowse link
G Hspa4l heat shock protein 4 like increases expression ISO manganese chloride results in increased expression of HSPA4L mRNA CTD PMID:28801915 NCBI chr 3:40,698,664...40,750,538
Ensembl chr 3:40,699,814...40,750,538
JBrowse link
G Hspa5 heat shock protein 5 multiple interactions
increases expression
ISO [manganese chloride results in increased abundance of Manganese] which results in increased expression of HSPA5 mRNA; SNCA protein promotes the reaction [manganese chloride results in increased expression of HSPA5 mRNA]; SNCA protein promotes the reaction [manganese chloride results in increased expression of HSPA5 protein]
manganese chloride results in increased expression of HSPA5 mRNA; manganese chloride results in increased expression of HSPA5 protein
CTD PMID:23934647 PMID:23948121 PMID:25732873 PMID:32574669 NCBI chr 2:34,662,102...34,666,541
Ensembl chr 2:34,661,982...34,667,559
JBrowse link
G Hspb8 heat shock protein 8 decreases expression ISO manganese chloride results in decreased expression of HSPB8 mRNA CTD PMID:28801915 NCBI chr 5:116,546,550...116,560,923
Ensembl chr 5:116,546,550...116,560,923
JBrowse link
G Htra1 HtrA serine peptidase 1 increases expression ISO manganese chloride results in increased expression of HTRA1 mRNA CTD PMID:28801915 NCBI chr 7:130,537,933...130,587,388
Ensembl chr 7:130,537,841...130,587,390
JBrowse link
G Htt huntingtin affects response to substance EXP HTT affects the susceptibility to manganese chloride CTD PMID:22363539 NCBI chr 5:34,919,084...35,069,878
Ensembl chr 5:34,919,084...35,069,878
JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions
decreases expression
ISO manganese chloride inhibits the reaction [CCL2 protein results in increased expression of ICAM1 protein]; manganese chloride inhibits the reaction [Glucose results in increased expression of ICAM1 protein]
manganese chloride results in decreased expression of ICAM1 protein
CTD PMID:23329836 NCBI chr 9:20,927,236...20,940,110
Ensembl chr 9:20,927,281...20,940,113
JBrowse link
G Id1 inhibitor of DNA binding 1, HLH protein increases expression EXP manganese chloride results in increased expression of ID1 mRNA CTD PMID:17467022 NCBI chr 2:152,578,171...152,579,330
Ensembl chr 2:152,578,171...152,579,330
JBrowse link
G Id2 inhibitor of DNA binding 2 increases expression
decreases expression
ISO manganese chloride results in increased expression of ID2 mRNA
manganese chloride results in decreased expression of ID2 mRNA
CTD PMID:17175027 PMID:28801915 NCBI chr12:25,143,798...25,146,091
Ensembl chr12:25,143,798...25,147,139
JBrowse link
G Idh3g isocitrate dehydrogenase 3 (NAD+), gamma multiple interactions EXP [manganese chloride results in increased abundance of Manganese] which results in decreased expression of IDH3G mRNA CTD PMID:35690225 NCBI chr  X:72,822,569...72,830,471
Ensembl chr  X:72,822,569...72,830,503
JBrowse link
G Ifi204 interferon activated gene 204 decreases expression ISO manganese chloride results in decreased expression of IFI204 mRNA CTD PMID:28801915 NCBI chr 1:173,574,859...173,594,606
Ensembl chr 1:173,574,859...173,594,509
JBrowse link
G Ifi211 interferon activated gene 211 decreases expression ISO manganese chloride results in decreased expression of IFI204 mRNA CTD PMID:28801915 NCBI chr 1:173,723,907...173,740,650
Ensembl chr 1:173,723,911...173,740,612
JBrowse link
G Ifng interferon gamma increases expression
multiple interactions
ISO
EXP
manganese chloride results in increased expression of IFNG protein
manganese chloride promotes the reaction [[TNF protein co-treated with IFNG protein] promotes the reaction [NOS2 protein results in increased chemical synthesis of Nitric Oxide]]; manganese chloride promotes the reaction [TNF protein co-treated with and results in increased chemical synthesis of IFNG protein co-treated with and results in increased chemical synthesis of Nitric Oxide]; manganese chloride promotes the reaction [TNF protein co-treated with and results in increased expression of IFNG protein co-treated with and results in increased expression of NOS2 mRNA]; manganese chloride promotes the reaction [TNF protein co-treated with and results in increased expression of IFNG protein co-treated with and results in increased expression of NOS2 protein]; NFKBIA protein affects the reaction [manganese chloride promotes the reaction [TNF protein co-treated with and results in increased chemical synthesis of IFNG protein co-treated with and results in increased chemical synthesis of Nitric Oxide]]; NFKBIA protein affects the reaction [manganese chloride promotes the reaction [TNF protein co-treated with and results in increased expression of IFNG protein co-treated with and results in increased expression of NOS2 mRNA]]; NFKBIA protein affects the reaction [manganese chloride promotes the reaction [TNF protein co-treated with and results in increased expression of IFNG protein co-treated with and results in increased expression of NOS2 protein]]
CTD PMID:16168523 PMID:20798247 NCBI chr10:118,276,951...118,281,799
Ensembl chr10:118,276,951...118,281,797
JBrowse link
G Ift70a1 intraflagellar transport 70A1 increases expression ISO manganese chloride results in increased expression of IFT70A1 mRNA CTD PMID:28801915 NCBI chr 2:75,809,450...75,812,311
Ensembl chr 2:75,808,591...75,812,311
JBrowse link
G Igf1 insulin-like growth factor 1 increases expression ISO manganese chloride results in increased expression of IGF1 mRNA CTD PMID:21402727 NCBI chr10:87,694,127...87,772,909
Ensembl chr10:87,694,127...87,772,904
JBrowse link
G Igf1r insulin-like growth factor I receptor increases expression
decreases expression
ISO manganese chloride results in increased expression of IGF1R protein
manganese chloride results in decreased expression of IGF1R mRNA
CTD PMID:19276553 PMID:21402727 NCBI chr 7:67,601,486...67,883,416
Ensembl chr 7:67,602,575...67,883,416
JBrowse link
G Igf2 insulin-like growth factor 2 decreases methylation ISO manganese chloride results in decreased methylation of IGF2 gene CTD PMID:27913844 NCBI chr 7:142,204,505...142,220,566
Ensembl chr 7:142,204,503...142,220,553
JBrowse link
G Igf2r insulin-like growth factor 2 receptor decreases expression ISO manganese chloride results in decreased expression of IGF2R mRNA CTD PMID:19276553 NCBI chr17:12,901,293...12,988,593
Ensembl chr17:12,901,293...12,988,551
JBrowse link
G Igfbp5 insulin-like growth factor binding protein 5 increases expression ISO manganese chloride results in increased expression of IGFBP5 mRNA CTD PMID:28801915 NCBI chr 1:72,897,224...72,914,024
Ensembl chr 1:72,897,091...72,914,043
JBrowse link
G Ikbkb inhibitor of kappaB kinase beta multiple interactions EXP
ISO
IKBKB gene mutant form results in increased susceptibility to [manganese chloride results in increased abundance of Manganese]
[manganese chloride results in increased abundance of Manganese] which results in increased phosphorylation of IKBKB protein; Acetylcysteine inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased phosphorylation of IKBKB protein]; alpha-Tocopherol inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased phosphorylation of IKBKB protein]; IkK-16 compound inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased phosphorylation of IKBKB protein]
CTD PMID:32692843 PMID:34310962 NCBI chr 8:23,149,228...23,196,605
Ensembl chr 8:23,149,228...23,196,605
JBrowse link
G Il12a interleukin 12a increases expression
multiple interactions
ISO
EXP
manganese chloride results in increased expression of IL12A mRNA
manganese chloride results in increased expression of [IL12A protein binds to IL12B protein]
manganese chloride promotes the reaction [SNCA protein results in increased expression of [IL12A protein binds to IL12B protein]]
CTD PMID:17175027 PMID:28539244 NCBI chr 3:68,597,977...68,605,881
Ensembl chr 3:68,597,977...68,605,880
JBrowse link
G Il12b interleukin 12b increases expression
multiple interactions
EXP
ISO
manganese chloride results in increased expression of IL12B mRNA
manganese chloride promotes the reaction [SNCA protein results in increased expression of [IL12A protein binds to IL12B protein]]
manganese chloride results in increased expression of [IL12A protein binds to IL12B protein]
CTD PMID:28539244 NCBI chr11:44,290,890...44,305,504
Ensembl chr11:44,290,890...44,304,860
JBrowse link
G Il18 interleukin 18 multiple interactions
increases expression
EXP acetovanillone analog inhibits the reaction [manganese chloride results in increased expression of IL18 mRNA] CTD PMID:28539244 NCBI chr 9:50,466,000...50,493,141
Ensembl chr 9:50,466,127...50,493,140
JBrowse link
G Il1a interleukin 1 alpha increases expression ISO manganese chloride results in increased expression of IL1A mRNA CTD PMID:25219578 NCBI chr 2:129,141,530...129,151,892
Ensembl chr 2:129,141,530...129,151,892
JBrowse link
G Il1b interleukin 1 beta increases expression
multiple interactions
decreases expression
ISO
EXP
manganese chloride results in increased expression of IL1B protein
[manganese chloride results in increased abundance of Manganese] which results in increased expression of IL1B protein; Ethanol promotes the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased expression of IL1B protein]; Minocycline inhibits the reaction [manganese chloride results in increased expression of IL1B protein]
[Lipopolysaccharides co-treated with manganese chloride] results in increased expression of IL1B protein; [manganese chloride results in increased abundance of Manganese] which results in increased expression of IL1B mRNA; [manganese chloride results in increased abundance of Manganese] which results in increased expression of IL1B protein; acetovanillone analog inhibits the reaction [manganese chloride results in increased expression of IL1B mRNA]
manganese chloride results in decreased expression of IL1B mRNA
[manganese chloride co-treated with SNCA protein] results in increased expression of IL1B mRNA; [manganese chloride co-treated with SNCA protein] results in increased expression of IL1B protein
CTD PMID:15601679 PMID:18836210 PMID:27427241 PMID:28539244 PMID:33314588 More... NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059
JBrowse link
G Il1r1 interleukin 1 receptor, type I increases expression ISO manganese chloride results in increased expression of IL1R1 mRNA CTD PMID:28801915 NCBI chr 1:40,261,651...40,355,361
Ensembl chr 1:40,264,240...40,356,417
JBrowse link
G Il1r2 interleukin 1 receptor, type II increases expression ISO manganese chloride results in increased expression of IL1R2 mRNA CTD PMID:28801915 NCBI chr 1:40,123,872...40,164,390
Ensembl chr 1:40,113,239...40,164,391
JBrowse link
G Il1rl1 interleukin 1 receptor-like 1 decreases expression
increases expression
ISO manganese chloride results in decreased expression of IL1RL1 mRNA
manganese chloride results in increased expression of IL1RL1 mRNA
CTD PMID:26745496 PMID:28801915 NCBI chr 1:40,444,105...40,504,575
Ensembl chr 1:40,468,730...40,504,575
JBrowse link
G Il1rn interleukin 1 receptor antagonist increases expression ISO manganese chloride results in increased expression of IL1RN mRNA CTD PMID:28801915 NCBI chr 2:24,226,872...24,241,503
Ensembl chr 2:24,226,865...24,241,506
JBrowse link
G Il23a interleukin 23, alpha subunit p19 increases expression ISO manganese chloride results in increased expression of IL23A mRNA CTD PMID:28801915 NCBI chr10:128,132,009...128,133,953
Ensembl chr10:128,132,008...128,134,621
JBrowse link
G Il36rn interleukin 36 receptor antagonist increases expression ISO manganese chloride results in increased expression of IL36RN mRNA CTD PMID:28801915 NCBI chr 2:24,166,966...24,172,444
Ensembl chr 2:24,166,966...24,173,438
JBrowse link
G Il4 interleukin 4 multiple interactions EXP [manganese chloride results in increased abundance of Manganese] which results in increased expression of IL4 mRNA; [manganese chloride results in increased abundance of Manganese] which results in increased expression of IL4 protein CTD PMID:34018660 NCBI chr11:53,503,287...53,509,492
Ensembl chr11:53,493,809...53,509,496
JBrowse link
G Il6 interleukin 6 multiple interactions
increases expression
decreases expression
increases secretion
EXP
ISO
6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [manganese chloride promotes the reaction [Lipopolysaccharides results in increased expression of IL6 protein]]; [manganese chloride results in increased abundance of Manganese] which results in increased expression of IL6 mRNA; [manganese chloride results in increased abundance of Manganese] which results in increased expression of IL6 protein; Buthionine Sulfoximine inhibits the reaction [manganese chloride promotes the reaction [Lipopolysaccharides results in increased expression of IL6 protein]]; Lipopolysaccharides promotes the reaction [manganese chloride results in increased expression of IL6 protein]; manganese chloride promotes the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of IL6 mRNA]; manganese chloride promotes the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of IL6 protein]; manganese chloride promotes the reaction [Lipopolysaccharides results in increased expression of IL6 protein]; tin protoporphyrin IX inhibits the reaction [manganese chloride promotes the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of IL6 mRNA]]; Tosylphenylalanyl Chloromethyl Ketone inhibits the reaction [manganese chloride promotes the reaction [Lipopolysaccharides results in increased expression of IL6 protein]]; zinc protoporphyrin inhibits the reaction [manganese chloride promotes the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of IL6 protein]]
manganese chloride results in increased expression of IL6 mRNA
manganese chloride results in increased expression of IL6 mRNA; manganese chloride results in increased expression of IL6 protein
manganese chloride results in decreased expression of IL6 mRNA
manganese chloride results in increased secretion of IL6 protein
manganese chloride promotes the reaction [SNCA protein results in increased expression of IL6 mRNA]
CTD PMID:15601679 PMID:17065364 PMID:19815061 PMID:21963524 PMID:25219578 More... NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979
JBrowse link
G Il7 interleukin 7 increases expression ISO manganese chloride results in increased expression of IL7 mRNA CTD PMID:17175027 NCBI chr 3:7,637,088...7,678,820
Ensembl chr 3:7,635,054...7,678,820
JBrowse link
G Ins2 insulin II multiple interactions ISO [manganese chloride results in increased abundance of Manganese] inhibits the reaction [Glucose results in increased secretion of INS protein] CTD PMID:31555879 NCBI chr 7:142,232,393...142,233,463
Ensembl chr 7:142,232,393...142,297,118
JBrowse link
G Insig1 insulin induced gene 1 increases methylation
decreases expression
ISO manganese chloride results in increased methylation of INSIG1 gene
manganese chloride results in decreased expression of INSIG1 mRNA
CTD PMID:28801915 NCBI chr 5:28,276,410...28,283,660
Ensembl chr 5:28,276,361...28,283,660
JBrowse link
G Insr insulin receptor decreases expression
increases phosphorylation
increases expression
ISO manganese chloride results in decreased expression of INSR mRNA
manganese chloride results in increased phosphorylation of INSR protein
manganese chloride results in increased expression of INSR mRNA
CTD PMID:2475105 PMID:19276553 PMID:28801915 NCBI chr 8:3,200,922...3,329,649
Ensembl chr 8:3,172,061...3,329,617
JBrowse link
G Ints2 integrator complex subunit 2 decreases expression ISO manganese chloride results in decreased expression of INTS2 mRNA CTD PMID:28801915 NCBI chr11:86,101,507...86,148,912
Ensembl chr11:86,101,507...86,148,401
JBrowse link
G Ipo11 importin 11 decreases expression ISO manganese chloride results in decreased expression of IPO11 mRNA CTD PMID:17175027 NCBI chr13:106,930,947...107,073,466
Ensembl chr13:106,930,947...107,073,466
JBrowse link
G Iqcg IQ motif containing G increases expression ISO manganese chloride results in increased expression of IQCG mRNA CTD PMID:28801915 NCBI chr16:32,834,640...32,876,617
Ensembl chr16:32,833,053...32,876,588
JBrowse link
G Iqgap1 IQ motif containing GTPase activating protein 1 increases expression ISO manganese chloride results in increased expression of IQGAP1 mRNA CTD PMID:28801915 NCBI chr 7:80,361,331...80,453,288
Ensembl chr 7:80,361,331...80,475,722
JBrowse link
G Ireb2 iron responsive element binding protein 2 decreases activity
increases activity
ISO manganese chloride results in decreased activity of IREB2 protein
manganese chloride results in increased activity of IREB2 protein
CTD PMID:15893546 PMID:16568477 NCBI chr 9:54,769,942...54,819,812
Ensembl chr 9:54,771,073...54,819,814
JBrowse link
G Irf2 interferon regulatory factor 2 decreases expression ISO manganese chloride results in decreased expression of IRF2 mRNA CTD PMID:28801915 NCBI chr 8:47,192,751...47,300,493
Ensembl chr 8:47,192,767...47,300,493
JBrowse link
G Ism1 isthmin 1, angiogenesis inhibitor increases expression ISO manganese chloride results in increased expression of ISM1 mRNA CTD PMID:28801915 NCBI chr 2:139,515,169...139,600,500
Ensembl chr 2:139,520,098...139,600,501
JBrowse link
G Itga10 integrin, alpha 10 increases expression ISO manganese chloride results in increased expression of ITGA10 mRNA CTD PMID:28801915 NCBI chr 3:96,552,900...96,571,835
Ensembl chr 3:96,552,900...96,571,835
JBrowse link
G Itga2b integrin alpha 2b multiple interactions EXP manganese chloride inhibits the reaction [TLN1 protein mutant form results in decreased activity of [ITGB3 protein binds to ITGA2B protein]]; manganese chloride results in increased activity of [ITGB3 protein binds to ITGA2B protein] CTD PMID:20971947 NCBI chr11:102,344,134...102,360,570
Ensembl chr11:102,344,123...102,360,948
JBrowse link
G Itga3 integrin alpha 3 increases expression ISO manganese chloride results in increased expression of ITGA3 mRNA CTD PMID:17175027 NCBI chr11:94,935,301...94,967,637
Ensembl chr11:94,935,300...94,967,627
JBrowse link
G Itga8 integrin alpha 8 increases expression
increases methylation
ISO manganese chloride results in increased expression of ITGA8 mRNA
manganese chloride results in increased methylation of ITGA8 gene
CTD PMID:28801915 NCBI chr 2:12,111,443...12,306,755
Ensembl chr 2:12,111,443...12,306,733
JBrowse link
G Itgam integrin alpha M increases expression ISO manganese chloride results in increased expression of ITGAM protein CTD PMID:12106697 NCBI chr 7:127,661,812...127,717,663
Ensembl chr 7:127,661,812...127,717,663
JBrowse link
G Itgav integrin alpha V multiple interactions ISO 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [manganese chloride affects the localization of and affects the activity of [ITGB3 protein binds to ITGAV protein]]; [AG 1879 results in decreased activity of SRC protein] promotes the reaction [manganese chloride affects the localization of and affects the activity of [ITGB3 protein binds to ITGAV protein]]; [CGP 77675 results in decreased activity of SRC protein] promotes the reaction [manganese chloride affects the localization of and affects the activity of [ITGB3 protein binds to ITGAV protein]]; arginyl-glycyl-aspartic acid inhibits the reaction [manganese chloride affects the localization of and affects the activity of [ITGB3 protein binds to ITGAV protein]]; manganese chloride affects the localization of and affects the activity of [ITGB3 protein binds to ITGAV protein]; wortmannin inhibits the reaction [manganese chloride affects the localization of and affects the activity of [ITGB3 protein binds to ITGAV protein]] CTD PMID:15213856 NCBI chr 2:83,554,796...83,637,261
Ensembl chr 2:83,554,741...83,637,260
JBrowse link
G Itgb3 integrin beta 3 multiple interactions EXP
ISO
manganese chloride inhibits the reaction [TLN1 protein mutant form results in decreased activity of [ITGB3 protein binds to ITGA2B protein]]; manganese chloride results in increased activity of [ITGB3 protein binds to ITGA2B protein]
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [manganese chloride affects the localization of and affects the activity of [ITGB3 protein binds to ITGAV protein]]; [AG 1879 results in decreased activity of SRC protein] promotes the reaction [manganese chloride affects the localization of and affects the activity of [ITGB3 protein binds to ITGAV protein]]; [CGP 77675 results in decreased activity of SRC protein] promotes the reaction [manganese chloride affects the localization of and affects the activity of [ITGB3 protein binds to ITGAV protein]]; arginyl-glycyl-aspartic acid inhibits the reaction [manganese chloride affects the localization of and affects the activity of [ITGB3 protein binds to ITGAV protein]]; manganese chloride affects the localization of and affects the activity of [ITGB3 protein binds to ITGAV protein]; wortmannin inhibits the reaction [manganese chloride affects the localization of and affects the activity of [ITGB3 protein binds to ITGAV protein]]
CTD PMID:15213856 PMID:20971947 NCBI chr11:104,498,826...104,561,302
Ensembl chr11:104,498,826...104,561,302
JBrowse link
G Itgb5 integrin beta 5 increases expression ISO manganese chloride results in increased expression of ITGB5 mRNA CTD PMID:17175027 NCBI chr16:33,650,021...33,769,708
Ensembl chr16:33,650,035...33,769,708
JBrowse link
G Itgb6 integrin beta 6 decreases methylation
increases expression
increases methylation
ISO manganese chloride results in decreased methylation of ITGB6 gene
manganese chloride results in increased expression of ITGB6 mRNA
manganese chloride results in increased methylation of ITGB6 gene
CTD PMID:27913844 PMID:28801915 NCBI chr 2:60,428,636...60,553,005
Ensembl chr 2:60,428,636...60,552,987
JBrowse link
G Itih1 inter-alpha trypsin inhibitor, heavy chain 1 multiple interactions ISO manganese chloride promotes the reaction [ITIH1 protein binds to TNFAIP6 protein] CTD PMID:16768462 NCBI chr14:30,651,137...30,665,246
Ensembl chr14:30,651,137...30,665,246
JBrowse link
G Itih2 inter-alpha trypsin inhibitor, heavy chain 2 multiple interactions ISO manganese chloride promotes the reaction [ITIH2 protein binds to TNFAIP6 protein] CTD PMID:16768462 NCBI chr 2:10,099,408...10,135,492
Ensembl chr 2:10,099,404...10,136,207
JBrowse link
G Jun jun proto-oncogene multiple interactions
increases phosphorylation
ISO manganese chloride results in increased expression of and results in increased phosphorylation of JUN protein; pyrazolanthrone inhibits the reaction [manganese chloride results in increased phosphorylation of JUN protein] CTD PMID:9751194 PMID:15342272 NCBI chr 4:94,937,273...94,940,459
Ensembl chr 4:94,937,271...94,940,459
JBrowse link
G Kcng1 potassium voltage-gated channel, subfamily G, member 1 increases expression ISO manganese chloride results in increased expression of KCNG1 mRNA CTD PMID:28801915 NCBI chr 2:168,102,037...168,123,453
Ensembl chr 2:168,102,037...168,123,656
JBrowse link
G Kcnh4 potassium voltage-gated channel, subfamily H (eag-related), member 4 decreases expression ISO manganese chloride results in decreased expression of KCNH4 mRNA CTD PMID:28801915 NCBI chr11:100,631,204...100,650,941
Ensembl chr11:100,631,202...100,650,768
JBrowse link
G Kcnh6 potassium voltage-gated channel, subfamily H (eag-related), member 6 increases expression ISO manganese chloride results in increased expression of KCNH6 mRNA CTD PMID:28801915 NCBI chr11:105,898,871...105,926,421
Ensembl chr11:105,898,950...105,925,375
JBrowse link
G Kcnip3 Kv channel interacting protein 3, calsenilin increases expression ISO manganese chloride results in increased expression of KCNIP3 mRNA CTD PMID:17175027 NCBI chr 2:127,298,418...127,364,014
Ensembl chr 2:127,298,418...127,364,014
JBrowse link
G Kcnj11 potassium inwardly rectifying channel, subfamily J, member 11 multiple interactions ISO [manganese chloride results in increased abundance of Manganese] which results in decreased expression of KCNJ11 protein CTD PMID:32659473 NCBI chr 7:45,746,545...45,750,215
Ensembl chr 7:45,743,377...45,750,188
JBrowse link
G Kcnj3 potassium inwardly-rectifying channel, subfamily J, member 3 increases expression ISO manganese chloride results in increased expression of KCNJ3 mRNA CTD PMID:17175027 NCBI chr 2:55,301,814...55,488,157
Ensembl chr 2:55,325,982...55,488,157
JBrowse link
G Kcnj8 potassium inwardly-rectifying channel, subfamily J, member 8 multiple interactions ISO [manganese chloride results in increased abundance of Manganese] which results in decreased expression of KCNJ8 protein CTD PMID:32659473 NCBI chr 6:142,510,563...142,517,340
Ensembl chr 6:142,510,563...142,517,340
JBrowse link
G Kcnk12 potassium channel, subfamily K, member 12 decreases expression ISO manganese chloride results in decreased expression of KCNK12 mRNA CTD PMID:28801915 NCBI chr17:88,049,100...88,106,329
Ensembl chr17:88,053,229...88,105,422
JBrowse link
G Kcnq1 potassium voltage-gated channel, subfamily Q, member 1 increases expression ISO manganese chloride results in increased expression of KCNQ1 mRNA CTD PMID:28801915 NCBI chr 7:142,660,614...142,980,787
Ensembl chr 7:142,660,099...142,980,779
JBrowse link
G Kcnq2 potassium voltage-gated channel, subfamily Q, member 2 increases expression ISO manganese chloride results in increased expression of KCNQ2 mRNA CTD PMID:28801915 NCBI chr 2:180,717,372...180,777,368
Ensembl chr 2:180,717,372...180,777,093
JBrowse link
G Keap1 kelch-like ECH-associated protein 1 affects expression
multiple interactions
EXP manganese chloride affects the expression of KEAP1 protein
Melatonin affects the reaction [manganese chloride affects the expression of KEAP1 protein]
CTD PMID:25288107 NCBI chr 9:21,141,026...21,150,628
Ensembl chr 9:21,141,026...21,150,657
JBrowse link
G Kera keratocan increases expression ISO manganese chloride results in increased expression of KERA mRNA CTD PMID:26745496 NCBI chr10:97,442,873...97,449,555
Ensembl chr10:97,442,741...97,449,554
JBrowse link
G Kif3b kinesin family member 3B increases expression ISO manganese chloride results in increased expression of KIF3B mRNA CTD PMID:28801915 NCBI chr 2:153,132,028...153,175,310
Ensembl chr 2:153,133,333...153,175,310
JBrowse link
G Kif5c kinesin family member 5C increases expression ISO manganese chloride results in increased expression of KIF5C mRNA CTD PMID:28801915 NCBI chr 2:49,509,298...49,664,790
Ensembl chr 2:49,509,310...49,664,790
JBrowse link
G Kiss1r KISS1 receptor increases expression ISO manganese chloride results in increased expression of KISS1R mRNA CTD PMID:28801915 NCBI chr10:79,752,786...79,759,922
Ensembl chr10:79,752,805...79,758,107
JBrowse link
G Klf2 Kruppel-like transcription factor 2 (lung) increases expression ISO manganese chloride results in increased expression of KLF2 mRNA CTD PMID:28801915 NCBI chr 8:73,072,906...73,075,498
Ensembl chr 8:73,072,877...73,075,500
JBrowse link
G Klf4 Kruppel-like transcription factor 4 (gut) increases expression ISO manganese chloride results in increased expression of KLF4 mRNA CTD PMID:17175027 NCBI chr 4:55,527,137...55,536,984
Ensembl chr 4:55,527,143...55,532,466
JBrowse link
G Klf5 Kruppel-like transcription factor 5 decreases expression
decreases methylation
increases expression
EXP
ISO
manganese chloride results in decreased expression of KLF5 mRNA
manganese chloride results in decreased methylation of KLF5 gene
manganese chloride results in increased expression of KLF5 mRNA
CTD PMID:17467022 PMID:28801915 NCBI chr14:99,536,127...99,550,848
Ensembl chr14:99,536,127...99,552,472
JBrowse link
G Klf9 Kruppel-like transcription factor 9 decreases expression ISO manganese chloride results in decreased expression of KLF9 mRNA CTD PMID:17175027 NCBI chr19:23,118,590...23,145,493
Ensembl chr19:23,118,590...23,145,498
JBrowse link
G Klhdc8a kelch domain containing 8A increases expression ISO manganese chloride results in increased expression of KLHDC8A mRNA CTD PMID:28801915 NCBI chr 1:132,226,352...132,236,216
Ensembl chr 1:132,226,364...132,235,095
JBrowse link
G Kng1 kininogen 1 decreases expression ISO manganese chloride results in decreased expression of KNG1 mRNA CTD PMID:28801915 NCBI chr16:22,876,970...22,900,828
Ensembl chr16:22,876,615...22,900,828
JBrowse link
G Krt7 keratin 7 increases expression ISO manganese chloride results in increased expression of KRT7 mRNA CTD PMID:28801915 NCBI chr15:101,310,284...101,325,687
Ensembl chr15:101,308,924...101,328,194
JBrowse link
G Krt76 keratin 76 increases expression ISO manganese chloride results in increased expression of KRT76 mRNA CTD PMID:28801915 NCBI chr15:101,792,786...101,801,355
Ensembl chr15:101,792,786...101,801,355
JBrowse link
G Krt79 keratin 79 decreases expression ISO manganese chloride results in decreased expression of KRT79 mRNA CTD PMID:28801915 NCBI chr15:101,837,767...101,848,759
Ensembl chr15:101,837,767...101,848,759
JBrowse link
G Krt81 keratin 81 increases expression ISO manganese chloride results in increased expression of KRT81 mRNA CTD PMID:28801915 NCBI chr15:101,356,942...101,361,646
Ensembl chr15:101,356,942...101,361,632
JBrowse link
G Krt87 keratin 87 increases expression ISO manganese chloride results in increased expression of KRT83 mRNA CTD PMID:28801915 NCBI chr15:101,329,371...101,336,685
Ensembl chr15:101,328,919...101,336,685
JBrowse link
G Lacc1 laccase domain containing 1 increases expression ISO manganese chloride results in increased expression of LACC1 mRNA CTD PMID:28801915 NCBI chr14:77,261,640...77,274,344
Ensembl chr14:77,261,640...77,274,344
JBrowse link
G Lamp1 lysosomal-associated membrane protein 1 multiple interactions EXP [manganese chloride results in increased abundance of Manganese] which results in decreased expression of LAMP1 mRNA; [manganese chloride results in increased abundance of Manganese] which results in decreased expression of LAMP1 protein; U 0126 inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in decreased expression of LAMP1 mRNA]; U 0126 inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in decreased expression of LAMP1 protein] CTD PMID:31690173 NCBI chr 8:13,209,161...13,225,338
Ensembl chr 8:13,209,161...13,225,338
JBrowse link
G Lamp2 lysosomal-associated membrane protein 2 multiple interactions EXP [manganese chloride results in increased abundance of Manganese] which results in decreased expression of LAMP2 protein CTD PMID:31690173 NCBI chr  X:37,488,524...37,545,337
Ensembl chr  X:37,490,234...37,545,331
JBrowse link
G Lcat lecithin cholesterol acyltransferase increases expression ISO manganese chloride results in increased expression of LCAT mRNA CTD PMID:28801915 NCBI chr 8:106,666,183...106,670,034
Ensembl chr 8:106,666,183...106,670,014
JBrowse link
G Lck lymphocyte protein tyrosine kinase multiple interactions ISO [manganese chloride co-treated with LCK protein] results in increased phosphorylation of CD28 protein; Tetradecanoylphorbol Acetate inhibits the reaction [[manganese chloride co-treated with LCK protein] results in increased phosphorylation of CD28 protein] CTD PMID:8662792 NCBI chr 4:129,442,142...129,467,415
Ensembl chr 4:129,442,137...129,467,434
JBrowse link
G Ldlrad4 low density lipoprotein receptor class A domain containing 4 increases expression ISO manganese chloride results in increased expression of LDLRAD4 mRNA CTD PMID:28801915 NCBI chr18:68,065,345...68,393,621
Ensembl chr18:68,066,328...68,401,701
JBrowse link
G Lefty2 left-right determination factor 2 decreases expression ISO manganese chloride results in decreased expression of LEFTY2 mRNA CTD PMID:17175027 NCBI chr 1:180,720,673...180,726,672
Ensembl chr 1:180,720,673...180,726,668
JBrowse link
G Lgals3 lectin, galactose binding, soluble 3 increases expression ISO manganese chloride results in increased expression of LGALS3 mRNA CTD PMID:28801915 NCBI chr14:47,611,317...47,623,624
Ensembl chr14:47,605,208...47,623,617
JBrowse link
G Lgi4 leucine-rich repeat LGI family, member 4 increases expression ISO manganese chloride results in increased expression of LGI4 mRNA CTD PMID:28801915 NCBI chr 7:30,758,360...30,770,347
Ensembl chr 7:30,758,767...30,770,360
JBrowse link
G Lgr4 leucine-rich repeat-containing G protein-coupled receptor 4 decreases expression ISO manganese chloride results in decreased expression of LGR4 mRNA CTD PMID:28801915 NCBI chr 2:109,747,919...109,844,602
Ensembl chr 2:109,747,992...109,844,602
JBrowse link
G Lhb luteinizing hormone beta decreases expression
multiple interactions
ISO manganese chloride results in decreased expression of LHB protein
Quercetin inhibits the reaction [manganese chloride results in decreased expression of LHB protein]
CTD PMID:28040552 NCBI chr 7:45,070,370...45,071,278
Ensembl chr 7:45,070,244...45,071,321
JBrowse link
G Lhfpl2 lipoma HMGIC fusion partner-like 2 increases expression ISO manganese chloride results in increased expression of LHFPL2 mRNA CTD PMID:28801915 NCBI chr13:94,193,659...94,331,918
Ensembl chr13:94,194,304...94,331,917
JBrowse link
G Lhx1 LIM homeobox protein 1 decreases expression ISO manganese chloride results in decreased expression of LHX1 mRNA CTD PMID:28801915 NCBI chr11:84,408,801...84,416,360
Ensembl chr11:84,409,110...84,416,361
JBrowse link
G Lif leukemia inhibitory factor increases expression ISO manganese chloride results in increased expression of LIF mRNA CTD PMID:28801915 NCBI chr11:4,207,587...4,222,514
Ensembl chr11:4,207,557...4,222,514
JBrowse link
G Lman2 lectin, mannose-binding 2 increases expression ISO manganese chloride results in increased expression of LMAN2 mRNA CTD PMID:17175027 NCBI chr13:55,491,646...55,510,596
Ensembl chr13:55,491,646...55,510,596
JBrowse link
G Lmod2 leiomodin 2 (cardiac) decreases expression ISO manganese chloride results in decreased expression of LMOD2 mRNA CTD PMID:28801915 NCBI chr 6:24,597,770...24,605,413
Ensembl chr 6:24,597,761...24,605,413
JBrowse link
G Lox lysyl oxidase decreases expression ISO manganese chloride results in decreased expression of LOX mRNA CTD PMID:28801915 NCBI chr18:52,649,132...52,662,939
Ensembl chr18:52,649,139...52,662,939
JBrowse link
G Lpar1 lysophosphatidic acid receptor 1 decreases expression ISO manganese chloride results in decreased expression of LPAR1 mRNA CTD PMID:28801915 NCBI chr 4:58,435,252...58,554,601
Ensembl chr 4:58,435,255...58,553,898
JBrowse link
G Lpcat4 lysophosphatidylcholine acyltransferase 4 decreases expression ISO manganese chloride results in decreased expression of LPCAT4 mRNA CTD PMID:28801915 NCBI chr 2:112,070,186...112,077,456
Ensembl chr 2:112,069,813...112,077,456
JBrowse link
G Lpin1 lipin 1 decreases expression ISO manganese chloride results in decreased expression of LPIN1 mRNA CTD PMID:28801915 NCBI chr12:16,585,670...16,697,020
Ensembl chr12:16,585,670...16,696,967
JBrowse link
G Lrat lecithin-retinol acyltransferase (phosphatidylcholine-retinol-O-acyltransferase) increases expression ISO manganese chloride results in increased expression of LRAT mRNA CTD PMID:26745496 NCBI chr 3:82,799,889...82,811,281
Ensembl chr 3:82,799,886...82,811,280
JBrowse link
G Lrp2 low density lipoprotein receptor-related protein 2 decreases expression ISO manganese chloride results in decreased expression of LRP2 mRNA CTD PMID:28801915 NCBI chr 2:69,254,679...69,416,373
Ensembl chr 2:69,254,684...69,416,409
JBrowse link
G Lrp8 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor increases expression EXP manganese chloride results in increased expression of LRP8 mRNA CTD PMID:22407947 NCBI chr 4:107,659,337...107,734,037
Ensembl chr 4:107,659,066...107,734,037
JBrowse link
G Lrrc10b leucine rich repeat containing 10B increases methylation ISO manganese chloride results in increased methylation of LRRC10B gene CTD PMID:28801915 NCBI chr19:10,432,735...10,434,811
Ensembl chr19:10,432,735...10,434,837
JBrowse link
G Lrrc15 leucine rich repeat containing 15 increases expression ISO manganese chloride results in increased expression of LRRC15 mRNA CTD PMID:28801915 NCBI chr16:30,088,120...30,102,072
Ensembl chr16:30,088,120...30,102,074
JBrowse link
G Lrrc8b leucine rich repeat containing 8 family, member B increases expression ISO manganese chloride results in increased expression of LRRC8B mRNA CTD PMID:28801915 NCBI chr 5:105,563,072...105,637,945
Ensembl chr 5:105,563,641...105,637,940
JBrowse link
G Lrrk1 leucine-rich repeat kinase 1 increases expression ISO manganese chloride results in increased expression of LRRK1 mRNA CTD PMID:28801915 NCBI chr 7:65,908,493...66,038,089
Ensembl chr 7:65,876,660...66,038,098
JBrowse link
G Lsm2 LSM2 homolog, U6 small nuclear RNA and mRNA degradation associated multiple interactions EXP [manganese chloride results in increased abundance of Manganese] which results in decreased expression of LSM2 mRNA CTD PMID:35690225 NCBI chr17:35,200,830...35,204,867
Ensembl chr17:35,200,838...35,204,867
JBrowse link
G Ly6g5b lymphocyte antigen 6 family member G5B increases expression ISO manganese chloride results in increased expression of LY6G5B mRNA CTD PMID:28801915 NCBI chr17:35,332,920...35,337,534
Ensembl chr17:35,332,924...35,334,404
JBrowse link
G Lyn LYN proto-oncogene, Src family tyrosine kinase decreases methylation ISO manganese chloride results in decreased methylation of LYN gene CTD PMID:27913844 NCBI chr 4:3,676,865...3,791,613
Ensembl chr 4:3,678,115...3,813,122
JBrowse link
G Lypd6b LY6/PLAUR domain containing 6B decreases expression ISO manganese chloride results in decreased expression of LYPD6B mRNA CTD PMID:28801915 NCBI chr 2:49,677,380...49,838,861
Ensembl chr 2:49,677,700...49,838,861
JBrowse link
G Lyrm7 LYR motif containing 7 increases expression ISO manganese chloride results in increased expression of LYRM7 mRNA CTD PMID:28801915 NCBI chr11:54,717,692...54,751,738
Ensembl chr11:54,717,692...54,751,742
JBrowse link
G Lyrm9 LYR motif containing 9 increases expression ISO manganese chloride results in increased expression of LYRM9 mRNA CTD PMID:28801915 NCBI chr11:78,717,421...78,734,725
Ensembl chr11:78,717,410...78,737,696
JBrowse link
G Macrod2 mono-ADP ribosylhydrolase 2 increases expression ISO manganese chloride results in increased expression of MACROD2 mRNA CTD PMID:28801915 NCBI chr 2:140,237,223...142,234,886
Ensembl chr 2:140,237,229...142,234,886
JBrowse link
G Madcam1 mucosal vascular addressin cell adhesion molecule 1 increases expression ISO manganese chloride results in increased expression of MADCAM1 mRNA CTD PMID:28801915 NCBI chr10:79,500,393...79,504,376
Ensembl chr10:79,500,393...79,504,371
JBrowse link
G Maff v-maf musculoaponeurotic fibrosarcoma oncogene family, protein F (avian) increases expression ISO manganese chloride results in increased expression of MAFF mRNA CTD PMID:28801915 NCBI chr15:79,230,813...79,243,278
Ensembl chr15:79,230,821...79,243,276
JBrowse link
G Mall mal, T cell differentiation protein-like decreases expression ISO manganese chloride results in decreased expression of MALL mRNA CTD PMID:26745496 NCBI chr 2:127,546,310...127,571,817
Ensembl chr 2:127,546,306...127,571,852
JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta multiple interactions EXP [manganese chloride results in increased abundance of Manganese] which results in decreased expression of MAP1LC3B mRNA; U 0126 inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in decreased expression of MAP1LC3B mRNA] CTD PMID:31690173 NCBI chr 8:122,317,177...122,325,499
Ensembl chr 8:122,317,100...122,325,499
JBrowse link
G Map2 microtubule-associated protein 2 decreases expression ISO manganese chloride results in decreased expression of MAP2 mRNA CTD PMID:28801915 NCBI chr 1:66,214,337...66,481,742
Ensembl chr 1:66,214,432...66,481,742
JBrowse link
G Map2k3 mitogen-activated protein kinase kinase 3 decreases methylation ISO manganese chloride results in decreased methylation of MAP2K3 gene CTD PMID:27913844 NCBI chr11:60,822,880...60,843,637
Ensembl chr11:60,822,859...60,843,637
JBrowse link
G Map2k4 mitogen-activated protein kinase kinase 4 increases phosphorylation ISO manganese chloride results in increased phosphorylation of MAP2K4 protein CTD PMID:9751194 PMID:15342272 NCBI chr11:65,579,070...65,679,185
Ensembl chr11:65,579,069...65,679,123
JBrowse link
G Map3k11 mitogen-activated protein kinase kinase kinase 11 increases phosphorylation ISO manganese chloride results in increased phosphorylation of MAP3K11 protein CTD PMID:15342272 NCBI chr19:5,738,764...5,752,893
Ensembl chr19:5,738,770...5,752,893
JBrowse link
G Map3k7 mitogen-activated protein kinase kinase kinase 7 increases methylation ISO manganese chloride results in increased methylation of MAP3K7 gene CTD PMID:27913844 NCBI chr 4:31,963,659...32,023,470
Ensembl chr 4:31,964,097...32,023,467
JBrowse link
G Map4k3 mitogen-activated protein kinase kinase kinase kinase 3 decreases expression ISO manganese chloride results in decreased expression of MAP4K3 mRNA CTD PMID:28801915 NCBI chr17:80,887,942...81,039,118
Ensembl chr17:80,887,941...81,035,914
JBrowse link
G Map7 microtubule-associated protein 7 increases expression ISO manganese chloride results in increased expression of MAP7 mRNA CTD PMID:28801915 NCBI chr10:20,024,666...20,157,336
Ensembl chr10:20,024,217...20,157,336
JBrowse link
G Map7d2 MAP7 domain containing 2 increases methylation
decreases expression
ISO manganese chloride results in increased methylation of MAP7D2 gene
manganese chloride results in decreased expression of MAP7D2 mRNA
CTD PMID:28801915 NCBI chr  X:158,197,488...158,281,954
Ensembl chr  X:158,197,568...158,281,753
JBrowse link
G Mapk1 mitogen-activated protein kinase 1 multiple interactions
increases activity
increases phosphorylation
decreases phosphorylation
ISO
EXP
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [manganese chloride results in increased phosphorylation of MAPK1 protein]; [manganese chloride results in increased abundance of Manganese] which results in increased phosphorylation of MAPK1 protein; GW 506033X promotes the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased phosphorylation of MAPK1 protein]; manganese chloride results in increased phosphorylation of and results in increased activity of MAPK1 protein; pyrazolanthrone promotes the reaction [manganese chloride results in increased phosphorylation of MAPK1 protein]; Resveratrol inhibits the reaction [manganese chloride results in increased phosphorylation of MAPK1 protein]; U 0126 inhibits the reaction [manganese chloride results in increased phosphorylation of MAPK1 protein]
manganese chloride results in increased activity of MAPK1 protein
manganese chloride results in decreased phosphorylation of MAPK1 protein
[manganese chloride results in increased abundance of Manganese] which results in decreased phosphorylation of MAPK1 protein; [manganese chloride results in increased abundance of Manganese] which results in increased phosphorylation of MAPK1 protein; benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in decreased phosphorylation of MAPK1 protein]; U 0126 inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased phosphorylation of MAPK1 protein]
NTF3 protein inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in decreased phosphorylation of MAPK1 protein]
CTD PMID:15010209 PMID:15342272 PMID:16787641 PMID:19084589 PMID:20152896 More... NCBI chr16:16,801,246...16,865,317
Ensembl chr16:16,801,246...16,865,317
JBrowse link
G Mapk11 mitogen-activated protein kinase 11 increases expression ISO manganese chloride results in increased expression of MAPK11 mRNA CTD PMID:28801915 NCBI chr15:89,026,685...89,033,809
Ensembl chr15:89,026,689...89,033,831
JBrowse link
G Mapk14 mitogen-activated protein kinase 14 increases phosphorylation
increases expression
ISO
EXP
manganese chloride results in increased phosphorylation of MAPK14 protein
manganese chloride results in increased expression of MAPK14 mRNA
CTD PMID:15737199 PMID:17467022 NCBI chr17:28,910,316...28,967,379
Ensembl chr17:28,910,303...28,967,380
JBrowse link
G Mapk3 mitogen-activated protein kinase 3 multiple interactions
increases activity
increases phosphorylation
decreases phosphorylation
ISO
EXP
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [manganese chloride results in increased phosphorylation of MAPK3 protein]; [manganese chloride results in increased abundance of Manganese] which results in increased phosphorylation of MAPK3 protein; GW 506033X promotes the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased phosphorylation of MAPK3 protein]; manganese chloride results in increased phosphorylation of and results in increased activity of MAPK3 protein; pyrazolanthrone promotes the reaction [manganese chloride results in increased phosphorylation of MAPK3 protein]; Resveratrol inhibits the reaction [manganese chloride results in increased phosphorylation of MAPK3 protein]; U 0126 inhibits the reaction [manganese chloride results in increased phosphorylation of MAPK3 protein]
manganese chloride results in increased activity of MAPK3 protein
manganese chloride results in decreased phosphorylation of MAPK3 protein
[manganese chloride results in increased abundance of Manganese] which results in decreased phosphorylation of MAPK3 protein; [manganese chloride results in increased abundance of Manganese] which results in increased phosphorylation of MAPK3 protein; benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in decreased phosphorylation of MAPK3 protein]; U 0126 inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased phosphorylation of MAPK3 protein]
NTF3 protein inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in decreased phosphorylation of MAPK3 protein]
CTD PMID:15010209 PMID:15342272 PMID:16787641 PMID:19084589 PMID:20152896 More... NCBI chr 7:126,358,798...126,364,988
Ensembl chr 7:126,358,773...126,364,991
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 increases activity
increases phosphorylation
increases methylation
multiple interactions
ISO manganese chloride results in increased activity of MAPK8 protein
manganese chloride results in increased phosphorylation of MAPK8 protein
manganese chloride results in increased methylation of MAPK8 gene
[manganese chloride results in increased abundance of Manganese] which results in increased phosphorylation of MAPK8 protein; pyrazolanthrone inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased phosphorylation of MAPK8 protein]
CTD PMID:19084589 PMID:20152896 PMID:24324973 PMID:27913844 PMID:30951808 More... NCBI chr14:33,099,855...33,169,213
Ensembl chr14:33,099,855...33,169,115
JBrowse link
G Mapk9 mitogen-activated protein kinase 9 increases activity
increases phosphorylation
ISO manganese chloride results in increased activity of MAPK9 protein
manganese chloride results in increased phosphorylation of MAPK9 protein
CTD PMID:19084589 PMID:20152896 NCBI chr11:49,737,558...49,777,248
Ensembl chr11:49,737,578...49,777,248
JBrowse link
G Mapt microtubule-associated protein tau multiple interactions
increases phosphorylation
ISO 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [manganese chloride results in increased phosphorylation of MAPT protein]; [Lithium Chloride results in decreased activity of GSK3B protein] inhibits the reaction [manganese chloride results in increased phosphorylation of MAPT protein]; GSK3B protein affects the reaction [manganese chloride results in increased phosphorylation of MAPT protein] CTD PMID:20937724 NCBI chr11:104,120,235...104,222,916
Ensembl chr11:104,122,216...104,222,916
JBrowse link
G Masp1 MBL associated serine protease 1 decreases methylation ISO manganese chloride results in decreased methylation of MASP1 gene CTD PMID:27913844 NCBI chr16:23,261,778...23,340,127
Ensembl chr16:23,268,167...23,339,565
JBrowse link
G Matn3 matrilin 3 decreases expression ISO manganese chloride results in decreased expression of MATN3 mRNA CTD PMID:28801915 NCBI chr12:8,997,929...9,022,028
Ensembl chr12:8,997,929...9,022,028
JBrowse link
G Mbp myelin basic protein increases expression ISO manganese chloride results in increased expression of MBP mRNA CTD PMID:17175027 NCBI chr18:82,492,883...82,603,762
Ensembl chr18:82,493,271...82,603,762
JBrowse link
G Mcf2l mcf.2 transforming sequence-like increases expression EXP manganese chloride results in increased expression of MCF2L mRNA CTD PMID:15295902 NCBI chr 8:12,923,806...13,070,502
Ensembl chr 8:12,923,806...13,070,905
JBrowse link
G Mchr1 melanin-concentrating hormone receptor 1 increases expression ISO manganese chloride results in increased expression of MCHR1 mRNA CTD PMID:17175027 NCBI chr15:81,119,700...81,123,165
Ensembl chr15:81,119,700...81,123,165
JBrowse link
G Mcl1 myeloid cell leukemia sequence 1 decreases expression ISO manganese chloride results in decreased expression of MCL1 protein CTD PMID:27107493 NCBI chr 3:95,564,017...95,583,553
Ensembl chr 3:95,566,099...95,570,487
JBrowse link
G Mcm4 minichromosome maintenance complex component 4 decreases expression ISO manganese chloride results in decreased expression of MCM4 mRNA CTD PMID:17175027 NCBI chr16:15,441,761...15,455,264
Ensembl chr16:15,441,761...15,455,264
JBrowse link
G Mcm5 minichromosome maintenance complex component 5 decreases expression ISO manganese chloride results in decreased expression of MCM5 mRNA CTD PMID:17175027 NCBI chr 8:75,836,096...75,855,067
Ensembl chr 8:75,836,197...75,855,067
JBrowse link
G Mcoln3 mucolipin 3 increases expression ISO manganese chloride results in increased expression of MCOLN3 mRNA CTD PMID:26745496 NCBI chr 3:145,799,032...145,847,563
Ensembl chr 3:145,823,205...145,847,561
JBrowse link
G Mdh1 malate dehydrogenase 1, NAD (soluble) multiple interactions EXP [manganese chloride results in increased abundance of Manganese] which results in decreased expression of MDH1 mRNA CTD PMID:35690225 NCBI chr11:21,506,692...21,521,934
Ensembl chr11:21,506,692...21,522,367
JBrowse link
G Mdm2 transformed mouse 3T3 cell double minute 2 increases expression ISO manganese chloride results in increased expression of MDM2 mRNA CTD PMID:28801915 NCBI chr10:117,524,780...117,546,663
Ensembl chr10:117,524,780...117,546,663
JBrowse link
G Me3 malic enzyme 3, NADP(+)-dependent, mitochondrial increases expression ISO manganese chloride results in increased expression of ME3 mRNA CTD PMID:17175027 NCBI chr 7:89,281,492...89,503,423
Ensembl chr 7:89,281,600...89,503,567
JBrowse link
G Medag mesenteric estrogen dependent adipogenesis increases expression ISO manganese chloride results in increased expression of MEDAG mRNA CTD PMID:28801915 NCBI chr 5:149,335,214...149,355,188
Ensembl chr 5:149,335,214...149,355,188
JBrowse link
G Mef2c myocyte enhancer factor 2C decreases expression
increases methylation
ISO manganese chloride results in decreased expression of MEF2C mRNA
manganese chloride results in increased methylation of MEF2C gene
CTD PMID:28801915 NCBI chr13:83,652,136...83,815,197
Ensembl chr13:83,652,153...83,815,199
JBrowse link
G Mepe matrix extracellular phosphoglycoprotein with ASARM motif (bone) increases methylation
increases expression
ISO manganese chloride results in increased methylation of MEPE gene
manganese chloride results in increased expression of MEPE mRNA
CTD PMID:28801915 NCBI chr 5:104,473,195...104,486,477
Ensembl chr 5:104,473,195...104,486,477
JBrowse link
G Metap2 methionine aminopeptidase 2 multiple interactions
increases activity
ISO manganese chloride inhibits the reaction [Triazoles results in decreased activity of METAP2 protein]
manganese chloride results in increased activity of METAP2 protein
CTD PMID:12718546 NCBI chr10:93,694,351...93,732,952
Ensembl chr10:93,694,351...93,732,955
JBrowse link
G Mfap2 microfibrillar-associated protein 2 decreases methylation
decreases expression
ISO manganese chloride results in decreased methylation of MFAP2 gene
manganese chloride results in decreased expression of MFAP2 mRNA
CTD PMID:28801915 NCBI chr 4:140,737,735...140,743,284
Ensembl chr 4:140,737,729...140,743,295
JBrowse link
G Mfn2 mitofusin 2 decreases expression
multiple interactions
EXP manganese chloride results in decreased expression of MFN2 mRNA; manganese chloride results in decreased expression of MFN2 protein
6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [Resveratrol inhibits the reaction [manganese chloride results in decreased expression of MFN2 protein]]; Resveratrol inhibits the reaction [manganese chloride results in decreased expression of MFN2 protein]
CTD PMID:28539244 PMID:34738708 NCBI chr 4:147,958,043...147,989,527
Ensembl chr 4:147,958,056...147,989,161
JBrowse link
G Mfsd6 major facilitator superfamily domain containing 6 increases expression ISO manganese chloride results in increased expression of MFSD6 mRNA CTD PMID:28801915 NCBI chr 1:52,695,463...52,766,495
Ensembl chr 1:52,695,445...52,766,621
JBrowse link
G Mga MAX gene associated increases expression ISO manganese chloride results in increased expression of MGA mRNA CTD PMID:28801915 NCBI chr 2:119,702,974...119,800,610
Ensembl chr 2:119,727,709...119,800,062
JBrowse link
G Mgat1 mannoside acetylglucosaminyltransferase 1 increases expression EXP manganese chloride results in increased expression of MGAT1 mRNA CTD PMID:15295902 NCBI chr11:49,135,018...49,153,854
Ensembl chr11:49,135,018...49,153,857
JBrowse link
G Mgat5b mannoside acetylglucosaminyltransferase 5, isoenzyme B increases expression ISO manganese chloride results in increased expression of MGAT5B mRNA CTD PMID:28801915 NCBI chr11:116,809,629...116,877,770
Ensembl chr11:116,809,689...116,877,774
JBrowse link
G Mgmt O-6-methylguanine-DNA methyltransferase increases methylation
increases expression
ISO manganese chloride results in increased methylation of MGMT gene
manganese chloride results in increased expression of MGMT mRNA
CTD PMID:27913844 PMID:28801915 NCBI chr 7:136,496,315...136,732,001
Ensembl chr 7:136,496,343...136,731,995
JBrowse link
G Mgp matrix Gla protein increases expression ISO manganese chloride results in increased expression of MGP mRNA CTD PMID:28801915 NCBI chr 6:136,849,433...136,852,821
Ensembl chr 6:136,849,433...136,852,821
JBrowse link
G Mgst1 microsomal glutathione S-transferase 1 decreases expression ISO manganese chloride results in decreased expression of MGST1 mRNA CTD PMID:28801915 NCBI chr 6:138,117,525...138,133,753
Ensembl chr 6:138,117,314...138,133,753
JBrowse link
G Mgst3 microsomal glutathione S-transferase 3 increases expression ISO manganese chloride results in increased expression of MGST3 mRNA CTD PMID:28801915 NCBI chr 1:167,199,535...167,221,410
Ensembl chr 1:167,199,535...167,221,410
JBrowse link
G Mia MIA SH3 domain containing increases expression ISO manganese chloride results in increased expression of MIA mRNA CTD PMID:17175027 PMID:28801915 NCBI chr 7:26,879,166...26,880,574
Ensembl chr 7:26,879,167...26,880,582
JBrowse link
G Mical1 microtubule associated monooxygenase, calponin and LIM domain containing 1 decreases expression ISO manganese chloride results in decreased expression of MICAL1 mRNA CTD PMID:28801915 NCBI chr10:41,351,693...41,363,026
Ensembl chr10:41,352,310...41,363,028
JBrowse link
G Mir107 microRNA 107 decreases expression ISO manganese chloride results in decreased expression of MIR107 mRNA CTD PMID:28986288 NCBI chr19:34,798,087...34,798,173
Ensembl chr19:34,798,087...34,798,173
JBrowse link
G Mir125b-1 microRNA 125b-1 multiple interactions ISO [manganese chloride results in increased abundance of Manganese] which results in increased expression of MIR125B1 mRNA CTD PMID:31555879 NCBI chr 9:41,493,222...41,493,298
Ensembl chr 9:41,493,222...41,493,298
JBrowse link
G Mir134 microRNA 134 increases expression ISO manganese chloride results in increased expression of MIR134 mRNA CTD PMID:28986288 NCBI chr12:109,700,573...109,700,643
Ensembl chr12:109,700,573...109,700,643
JBrowse link
G Mir139 microRNA 139 decreases expression ISO manganese chloride results in decreased expression of MIR139 mRNA CTD PMID:28986288 NCBI chr 7:101,124,583...101,124,650
Ensembl chr 7:101,124,583...101,124,650
JBrowse link
G Mir143 microRNA 143 multiple interactions ISO [manganese chloride results in increased abundance of Manganese] which results in decreased expression of MIR143 mRNA; [manganese chloride results in increased abundance of Manganese] which results in increased expression of MIR143 mRNA CTD PMID:38503349 NCBI chr18:61,782,267...61,782,329
Ensembl chr18:61,782,267...61,782,329
JBrowse link
G Mir146b microRNA 146b decreases expression ISO manganese chloride results in decreased expression of MIR146B mRNA CTD PMID:28986288 NCBI chr19:46,331,201...46,331,309
Ensembl chr19:46,331,201...46,331,309
JBrowse link
G Mir150 microRNA 150 multiple interactions ISO [manganese chloride results in increased abundance of Manganese] which results in decreased expression of MIR150 mRNA; [manganese chloride results in increased abundance of Manganese] which results in increased expression of MIR150 mRNA CTD PMID:38503349 NCBI chr 7:44,771,181...44,771,245
Ensembl chr 7:44,771,181...44,771,245
JBrowse link
G Mir15a microRNA 15a decreases expression ISO manganese chloride results in decreased expression of MIR15A mRNA CTD PMID:28986288 NCBI chr14:61,869,476...61,869,559
Ensembl chr14:61,869,476...61,869,559
JBrowse link
G Mir221 microRNA 221 multiple interactions ISO [manganese chloride results in increased abundance of Manganese] which results in decreased expression of MIR221 mRNA CTD PMID:38503349 NCBI chr  X:19,012,533...19,012,627
Ensembl chr  X:19,012,533...19,012,627
JBrowse link
G Mir298 microRNA 298 decreases expression ISO manganese chloride results in decreased expression of MIR298 mRNA CTD PMID:28986288 NCBI chr 2:174,109,297...174,109,378
Ensembl chr 2:174,109,297...174,109,378
JBrowse link
G Mir29a microRNA 29a decreases expression ISO manganese chloride results in decreased expression of MIR29A mRNA CTD PMID:28986288 NCBI chr 6:31,039,595...31,039,682
Ensembl chr 6:31,039,595...31,039,682
JBrowse link
G Mir31 microRNA 31 multiple interactions ISO [manganese chloride results in increased abundance of Manganese] which results in decreased expression of MIR31 mRNA CTD PMID:38503349 NCBI chr 4:88,828,794...88,828,899
Ensembl chr 4:88,828,794...88,828,899
JBrowse link
G Mir320 microRNA 320 increases expression ISO manganese chloride results in increased expression of MIR320A mRNA CTD PMID:28986288 NCBI chr14:70,680,950...70,681,031
Ensembl chr14:70,680,950...70,681,031
JBrowse link
G Mir328 microRNA 328 decreases expression ISO manganese chloride results in decreased expression of MIR328 mRNA CTD PMID:28986288 NCBI chr 8:106,034,996...106,035,092
Ensembl chr 8:106,034,996...106,035,092
JBrowse link
G Mir409 microRNA 409 decreases expression ISO manganese chloride results in decreased expression of MIR409 mRNA CTD PMID:28986288 NCBI chr12:109,709,592...109,709,670
Ensembl chr12:109,709,592...109,709,670
JBrowse link
G Mir433 microRNA 433 decreases expression ISO manganese chloride results in decreased expression of MIR433 mRNA CTD PMID:28986288 NCBI chr12:109,558,149...109,558,272
Ensembl chr12:109,558,149...109,558,272
JBrowse link
G Mir582 microRNA 582 multiple interactions ISO [manganese chloride results in increased abundance of Manganese] which results in decreased expression of MIR582 mRNA CTD PMID:31555879 NCBI chr13:109,461,278...109,461,358
Ensembl chr13:109,461,278...109,461,358
JBrowse link
G Mir98 microRNA 98 decreases expression ISO manganese chloride results in decreased expression of MIR98 mRNA CTD PMID:28986288 NCBI chr  X:150,696,210...150,696,317
Ensembl chr  X:150,696,210...150,696,317
JBrowse link
G Mir99a microRNA 99a multiple interactions ISO [manganese chloride results in increased abundance of Manganese] which results in decreased expression of MIR99A mRNA CTD PMID:38503349 NCBI chr16:77,395,824...77,395,888
Ensembl chr16:77,395,824...77,395,888
JBrowse link
G Mirlet7b microRNA let7b increases expression ISO manganese chloride results in increased expression of MIRLET7B mRNA CTD PMID:28986288 NCBI chr15:85,591,520...85,591,604
Ensembl chr15:85,591,520...85,591,604
JBrowse link
G Mirlet7e microRNA let7e increases expression ISO manganese chloride results in increased expression of MIRLET7E mRNA CTD PMID:28986288 NCBI chr17:18,050,614...18,050,706
Ensembl chr17:18,050,614...18,050,706
JBrowse link
G Mmab methylmalonic aciduria (cobalamin deficiency) cblB type homolog (human) decreases expression ISO manganese chloride results in decreased expression of MMAB mRNA CTD PMID:28801915 NCBI chr 5:114,569,095...114,582,134
Ensembl chr 5:114,569,095...114,582,121
JBrowse link
G Mmp13 matrix metallopeptidase 13 increases expression ISO manganese chloride results in increased expression of MMP13 mRNA CTD PMID:26745496 NCBI chr 9:7,272,514...7,283,333
Ensembl chr 9:7,272,514...7,283,331
JBrowse link
G Mmp14 matrix metallopeptidase 14 (membrane-inserted) decreases expression
increases methylation
ISO manganese chloride results in decreased expression of MMP14 mRNA
manganese chloride results in increased methylation of MMP14 gene
CTD PMID:28801915 NCBI chr14:54,669,055...54,679,913
Ensembl chr14:54,669,069...54,682,821
JBrowse link
G Mmp24 matrix metallopeptidase 24 increases expression ISO manganese chloride results in increased expression of MMP24 mRNA CTD PMID:28801915 NCBI chr 2:155,617,262...155,660,286
Ensembl chr 2:155,617,262...155,660,286
JBrowse link
G Mmp3 matrix metallopeptidase 3 increases expression ISO manganese chloride results in increased expression of MMP3 mRNA CTD PMID:26745496 NCBI chr 9:7,445,845...7,455,975
Ensembl chr 9:7,445,822...7,455,975
JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions
increases expression
ISO 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [manganese chloride results in increased expression of and results in increased secretion of MMP9 protein]; manganese chloride results in increased expression of and results in increased secretion of MMP9 protein; resveratrol inhibits the reaction [manganese chloride results in increased expression of and results in increased secretion of MMP9 protein]; resveratrol inhibits the reaction [manganese chloride results in increased expression of MMP9 mRNA] CTD PMID:23811825 NCBI chr 2:164,782,246...164,797,770
Ensembl chr 2:164,782,700...164,797,770
JBrowse link
G Mob3b MOB kinase activator 3B increases expression ISO manganese chloride results in increased expression of MOB3B mRNA CTD PMID:28801915 NCBI chr 4:34,949,074...35,157,490
Ensembl chr 4:34,949,074...35,157,484
JBrowse link
G Mon2 MON2 homolog, regulator of endosome to Golgi trafficking decreases expression ISO manganese chloride results in decreased expression of MON2 mRNA CTD PMID:28801915 NCBI chr10:122,827,965...122,913,684
Ensembl chr10:122,827,965...122,912,410
JBrowse link
G Mpo myeloperoxidase multiple interactions
increases activity
ISO diphenyleneiodonium inhibits the reaction [manganese chloride promotes the reaction [N-Formylmethionine Leucyl-Phenylalanine results in increased activity of MPO protein]]; manganese chloride promotes the reaction [N-Formylmethionine Leucyl-Phenylalanine results in increased activity of MPO protein]; manganese chloride promotes the reaction [Tetradecanoylphorbol Acetate results in increased activity of MPO protein]; Sodium Azide inhibits the reaction [manganese chloride promotes the reaction [N-Formylmethionine Leucyl-Phenylalanine results in increased activity of MPO protein]]
[manganese chloride results in increased abundance of Manganese] promotes the reaction [Ethanol results in increased activity of MPO protein]; [manganese chloride results in increased abundance of Manganese] which results in increased activity of MPO protein; Ethanol promotes the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased activity of MPO protein]; Quercetin inhibits the reaction [manganese chloride results in increased activity of MPO protein]
CTD PMID:22906169 PMID:28040552 PMID:30844427 PMID:33314588 NCBI chr11:87,684,610...87,695,238
Ensembl chr11:87,684,407...87,695,239
JBrowse link
G Mpp3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) increases expression ISO manganese chloride results in increased expression of MPP3 mRNA CTD PMID:28801915 NCBI chr11:101,890,488...101,925,854
Ensembl chr11:101,890,478...101,919,287
JBrowse link
G Mrps10 mitochondrial ribosomal protein S10 decreases expression ISO manganese chloride results in decreased expression of MRPS10 mRNA CTD PMID:28801915 NCBI chr17:47,679,803...47,692,343
Ensembl chr17:47,679,812...47,692,342
JBrowse link
G Ms4a6c membrane-spanning 4-domains, subfamily A, member 6C increases expression ISO manganese chloride results in increased expression of MS4A6A mRNA CTD PMID:28801915 NCBI chr19:11,446,718...11,464,433
Ensembl chr19:11,446,730...11,459,556
JBrowse link
G Msh5 mutS homolog 5 increases expression ISO manganese chloride results in increased expression of MSH5 mRNA CTD PMID:28801915 NCBI chr17:35,247,581...35,267,842
Ensembl chr17:35,247,581...35,265,721
JBrowse link
G Msh6 mutS homolog 6 decreases expression ISO manganese chloride results in decreased expression of MSH6 mRNA CTD PMID:17175027 NCBI chr17:88,282,478...88,298,320
Ensembl chr17:88,282,490...88,298,320
JBrowse link
G Msx2 msh homeobox 2 decreases expression