CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: sodium nitrate
Accession: CHEBI:63005
browse the term
Definition: The inorganic nitrate salt of sodium.
Synonyms: exact_synonym: sodium trioxidonitrate(1-)
related_synonym: Chile saltpeter; Cubic niter; Formula=NNaO3; InChI=1S/NO3.Na/c2-1(3)4;/q-1;+1; InChIKey=VWDWKYIASSYTQR-UHFFFAOYSA-N; Niter; Nitrate de sodium; Nitrate of soda; Nitric acid monosodium salt; Nitric acid sodium salt (1:1); Nitric acid, sodium salt; SMILES=[Na+].[O-][N+]([O-])=O; Sodium saltpeter; Sodium(I) nitrate (1:1)
xref: CAS:7631-99-4
xref_mesh: MESH:C031618
xref: Reaxys:11343077; Wikipedia:Sodium_nitrate
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Acadl
acyl-CoA dehydrogenase, long chain
multiple interactions
ISO
sodium nitrate inhibits the reaction [Doxorubicin results in increased expression of ACADL protein]
CTD
PMID:21251210
NCBI chr 9:68,333,981...68,372,149
Ensembl chr 9:68,333,980...68,372,220
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Actc1
actin, alpha, cardiac muscle 1
multiple interactions
ISO
sodium nitrate inhibits the reaction [Doxorubicin results in increased expression of ACTC1 protein]
CTD
PMID:21251210
NCBI chr 3:100,811,987...100,817,523
Ensembl chr 3:100,811,987...100,817,523
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Afp
alpha-fetoprotein
multiple interactions
ISO
sodium nitrate inhibits the reaction [Doxorubicin results in decreased expression of AFP protein]
CTD
PMID:21251210
NCBI chr14:17,573,412...17,591,476
Ensembl chr14:17,573,412...17,591,480
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Atp5f1b
ATP synthase F1 subunit beta
multiple interactions
ISO
sodium nitrate inhibits the reaction [Doxorubicin results in increased expression of ATP5F1B protein]
CTD
PMID:21251210
NCBI chr 7:515,454...521,858
Ensembl chr 7:515,460...567,273
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Atp5pd
ATP synthase peripheral stalk subunit d
multiple interactions
ISO
sodium nitrate inhibits the reaction [Doxorubicin results in increased expression of ATP5PD protein]
CTD
PMID:21251210
NCBI chr10:100,657,700...100,662,960
Ensembl chr10:100,657,708...100,663,479
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Cacna2d1
calcium voltage-gated channel auxiliary subunit alpha2delta 1
increases expression
ISO
sodium nitrate results in increased expression of CACNA2D1 protein
CTD
PMID:22687611
NCBI chr 4:18,950,611...19,374,969
Ensembl chr 4:18,951,002...19,374,969
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Casq1
calsequestrin 1
increases expression
ISO
sodium nitrate results in increased expression of CASQ1 protein
CTD
PMID:22687611
NCBI chr13:84,670,648...84,680,339
Ensembl chr13:84,670,649...84,680,339
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Cat
catalase
decreases activity
EXP
sodium nitrate results in decreased activity of CAT protein
CTD
PMID:24740966
NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
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Cox4i1
cytochrome c oxidase subunit 4i1
multiple interactions
ISO
sodium nitrate inhibits the reaction [Doxorubicin results in increased expression of COX4I1 protein]
CTD
PMID:21251210
NCBI chr19:48,721,680...48,727,920
Ensembl chr19:48,721,199...48,727,921
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Cryab
crystallin, alpha B
multiple interactions
ISO
sodium nitrate inhibits the reaction [Doxorubicin results in increased expression of CRYAB protein]
CTD
PMID:21251210
NCBI chr 8:51,093,441...51,099,161
Ensembl chr 8:51,093,441...51,099,157
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Duox2
dual oxidase 2
affects expression
EXP
sodium nitrate affects the expression of DUOX2 mRNA
CTD
PMID:34409734
NCBI chr 3:109,223,809...109,247,023
Ensembl chr 3:109,226,924...109,245,902
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Fabp3
fatty acid binding protein 3
multiple interactions
ISO
sodium nitrate inhibits the reaction [Doxorubicin results in increased expression of FABP3 protein]
CTD
PMID:21251210
NCBI chr 5:142,651,962...142,658,707
Ensembl chr 5:142,651,956...142,658,718
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Fth1
ferritin heavy chain 1
multiple interactions
ISO
sodium nitrate inhibits the reaction [Doxorubicin results in decreased expression of FTH1 protein]
CTD
PMID:21251210
NCBI chr 1:206,627,142...206,629,430
Ensembl chr 1:206,627,103...206,725,424
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G6pd
glucose-6-phosphate dehydrogenase
decreases activity
EXP
sodium nitrate results in decreased activity of G6PD protein
CTD
PMID:19922758
NCBI chr X:152,201,081...152,220,863
Ensembl chr X:152,201,098...152,220,801
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Got1
glutamic-oxaloacetic transaminase 1
multiple interactions
ISO
sodium nitrate inhibits the reaction [Doxorubicin results in increased expression of GOT1 protein]
CTD
PMID:21251210
NCBI chr 1:242,357,293...242,381,535
Ensembl chr 1:242,357,306...242,380,633
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Gsr
glutathione-disulfide reductase
multiple interactions
ISO
[Quercetin co-treated with sodium nitrate] results in increased activity of GSR protein
CTD
PMID:24860958
NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
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Idh3a
isocitrate dehydrogenase (NAD(+)) 3 catalytic subunit alpha
multiple interactions
ISO
sodium nitrate inhibits the reaction [Doxorubicin results in increased expression of IDH3A protein]
CTD
PMID:21251210
NCBI chr 8:54,971,694...54,991,085
Ensembl chr 8:54,971,740...54,991,084
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Ldhc
lactate dehydrogenase C
decreases activity
EXP
sodium nitrate results in decreased activity of LDHC protein
CTD
PMID:19922758
NCBI chr 1:97,385,984...97,403,382
Ensembl chr 1:97,382,379...97,403,378
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Mb
myoglobin
multiple interactions
ISO
sodium nitrate inhibits the reaction [Doxorubicin results in increased expression of MB protein]
CTD
PMID:21251210
NCBI chr 7:108,759,903...108,767,134
Ensembl chr 7:108,759,904...108,767,383
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Mpo
myeloperoxidase
multiple interactions
EXP
sodium nitrate inhibits the reaction [Diclofenac results in increased activity of MPO protein]
CTD
PMID:17275683
NCBI chr10:72,594,883...72,608,862
Ensembl chr10:72,594,661...72,604,819
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Muc6
mucin 6, oligomeric mucus/gel-forming
increases expression
EXP
sodium nitrate results in increased expression of MUC6 mRNA
CTD
PMID:17275683
NCBI chr 1:196,726,678...196,764,842
Ensembl chr 1:196,726,807...196,764,842
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Myh6
myosin heavy chain 6
multiple interactions
ISO
sodium nitrate inhibits the reaction [Doxorubicin results in decreased expression of MYH6 protein]
CTD
PMID:21251210
NCBI chr15:28,418,120...28,442,316
Ensembl chr15:28,417,616...28,441,720
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Myl2
myosin light chain 2
multiple interactions
ISO
[sodium nitrate co-treated with Doxorubicin] results in decreased expression of MYL2 protein; sodium nitrate inhibits the reaction [Doxorubicin results in increased expression of MYL2 protein]
CTD
PMID:21251210
NCBI chr12:34,454,223...34,468,554
Ensembl chr12:34,454,218...34,468,983
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Myl3
myosin light chain 3
multiple interactions
ISO
sodium nitrate inhibits the reaction [Doxorubicin results in increased expression of MYL3 protein]
CTD
PMID:21251210
NCBI chr 8:110,738,669...110,744,814
Ensembl chr 8:110,738,661...110,744,816
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Myoz2
myozenin 2
multiple interactions
ISO
sodium nitrate inhibits the reaction [Doxorubicin results in increased expression of MYOZ2 protein]
CTD
PMID:21251210
NCBI chr 2:211,141,463...211,168,187
Ensembl chr 2:211,141,463...211,168,221
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Nos2
nitric oxide synthase 2
multiple interactions
EXP
sodium nitrate inhibits the reaction [Diclofenac results in increased expression of NOS2 mRNA]
CTD
PMID:17275683
NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
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Nos3
nitric oxide synthase 3
multiple interactions
ISO
sodium nitrate inhibits the reaction [NOS3 gene mutant form results in increased abundance of Triglycerides]
CTD
PMID:20876122
NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166
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Pkm
pyruvate kinase M1/2
multiple interactions
ISO
sodium nitrate inhibits the reaction [Doxorubicin results in increased expression of PKM protein]
CTD
PMID:21251210
NCBI chr 8:60,057,629...60,079,600
Ensembl chr 8:60,057,402...60,079,599
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Prdx3
peroxiredoxin 3
multiple interactions
ISO
sodium nitrate inhibits the reaction [Doxorubicin results in increased expression of PRDX3 protein]
CTD
PMID:21251210
NCBI chr 1:260,001,642...260,014,064
Ensembl chr 1:260,001,637...260,014,111
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Prdx5
peroxiredoxin 5
increases expression multiple interactions
ISO
sodium nitrate results in increased expression of PRDX5 protein sodium nitrate inhibits the reaction [Doxorubicin results in decreased expression of PRDX5 protein]
CTD
PMID:21251210 PMID:22484629
NCBI chr 1:204,099,826...204,103,589
Ensembl chr 1:204,099,826...204,114,268
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Pygb
glycogen phosphorylase B
multiple interactions
ISO
sodium nitrate inhibits the reaction [Doxorubicin results in decreased expression of PYGB protein]
CTD
PMID:21251210
NCBI chr 3:139,611,724...139,658,521
Ensembl chr 3:139,611,749...139,663,553
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Pygm
glycogen phosphorylase, muscle associated
multiple interactions
ISO
sodium nitrate inhibits the reaction [Doxorubicin results in increased expression of PYGM protein]
CTD
PMID:21251210
NCBI chr 1:203,690,550...203,705,369
Ensembl chr 1:203,690,533...203,705,368
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Slc16a2
solute carrier family 16 member 2
increases expression
EXP
sodium nitrate results in increased expression of SLC16A2 mRNA
CTD
PMID:34409734
NCBI chr X:68,725,365...68,848,572
Ensembl chr X:68,723,261...68,848,771
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Slc26a4
solute carrier family 26 member 4
affects expression
EXP
sodium nitrate affects the expression of SLC26A4 mRNA
CTD
PMID:34409734
NCBI chr 6:48,107,575...48,153,762
Ensembl chr 6:48,107,588...48,145,703
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Sod2
superoxide dismutase 2
multiple interactions increases expression
ISO EXP
sodium nitrate inhibits the reaction [Doxorubicin results in increased expression of SOD2 protein] sodium nitrate results in increased expression of SOD2 mRNA
CTD
PMID:21251210 PMID:34409734
NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
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Srl
sarcalumenin
multiple interactions
ISO
sodium nitrate inhibits the reaction [Doxorubicin results in increased expression of SRL protein]
CTD
PMID:21251210
NCBI chr10:11,033,976...11,078,103
Ensembl chr10:11,034,035...11,078,101
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Suclg2
succinate-CoA ligase GDP-forming subunit beta
multiple interactions
ISO
sodium nitrate inhibits the reaction [Doxorubicin results in decreased expression of SUCLG2 protein]
CTD
PMID:21251210
NCBI chr 4:128,067,031...128,337,146
Ensembl chr 4:128,067,033...128,337,170
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Tg
thyroglobulin
decreases expression
EXP
sodium nitrate results in decreased expression of TG mRNA
CTD
PMID:34409734
NCBI chr 7:98,418,293...98,603,210
Ensembl chr 7:98,418,293...98,603,210
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Tpo
thyroid peroxidase
increases expression
EXP
sodium nitrate results in increased expression of TPO mRNA
CTD
PMID:34409734
NCBI chr 6:46,698,402...46,768,199
Ensembl chr 6:46,698,414...46,768,199
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Uqcrc1
ubiquinol-cytochrome c reductase core protein 1
multiple interactions
ISO
sodium nitrate inhibits the reaction [Doxorubicin results in increased expression of UQCRC1 protein]
CTD
PMID:21251210
NCBI chr 8:109,589,735...109,601,481
Ensembl chr 8:109,589,706...109,601,480
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Xdh
xanthine dehydrogenase
increases metabolic processing
ISO
XDH protein results in increased metabolism of sodium nitrate
CTD
PMID:20142047
NCBI chr 6:21,530,463...21,592,172
Ensembl chr 6:21,530,113...21,592,268
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Ywhaz
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
multiple interactions
ISO
sodium nitrate inhibits the reaction [Doxorubicin results in decreased expression of YWHAZ protein]
CTD
PMID:21251210
NCBI chr 7:67,941,353...67,963,651
Ensembl chr 7:67,940,017...67,963,668
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