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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:3beta-hydroxy-5alpha-cholest-8(14)-en-15-one
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Accession:CHEBI:61829 term browser browse the term
Definition:A 3beta-hydroxysteroid consisting of 3beta-hydroxy-5alpha-cholest-8(14)-ene having an additional oxo group at the 15-position.
Synonyms:related_synonym: (3beta,5alpha)-3-hydroxycholest-8(14)-en-15-one;   15-ketocholestene;   15-oxo-5alpha-cholest-8(14)-en-3beta-ol;   5alpha-cholest-8(14)-en-3-beta-ol-15-one;   Formula=C27H44O2;   InChI=1S/C27H44O2/c1-17(2)7-6-8-18(3)23-16-24(29)25-21-10-9-19-15-20(28)11-13-26(19,4)22(21)12-14-27(23,25)5/h17-20,22-23,28H,6-16H2,1-5H3/t18-,19+,20+,22+,23-,26+,27-/m1/s1;   InChIKey=LINVVMHRTUSXHL-GGVPDPBRSA-N;   SMILES=[H][C@@]12CCC3=C4C(=O)C[C@]([H])([C@H](C)CCCC(C)C)[C@@]4(C)CC[C@]3([H])[C@@]1(C)CC[C@H](O)C2;   colestolona;   colestolone;   colestolonum
 xref: CAS:50673-97-7;   LIPID_MAPS_instance:LMST01010269
 xref_mesh: MESH:C015073
 xref: PMID:1542104;   PMID:16341241;   PMID:8033288;   PMID:9779586;   Reaxys:3219975



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3beta-hydroxy-5alpha-cholest-8(14)-en-15-one term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase decreases activity ISO cholest-8(14)-en-3-ol-15-one results in decreased activity of HMGCR protein CTD PMID:7751816 NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703
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Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19917
    chemical entity 19915
      molecular entity 19915
        polyatomic entity 19868
          heteroatomic molecular entity 19826
            hydroxides 19379
              organic hydroxy compound 18986
                alcohol 15733
                  secondary alcohol 7764
                    3beta-hydroxy steroid 2542
                      3beta-hydroxy-5alpha-cholest-8(14)-en-15-one 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19917
    subatomic particle 19915
      composite particle 19915
        hadron 19915
          baryon 19915
            nucleon 19915
              atomic nucleus 19915
                atom 19915
                  main group element atom 19855
                    p-block element atom 19855
                      carbon group element atom 19794
                        carbon atom 19790
                          organic molecular entity 19790
                            organic molecule 19743
                              organic cyclic compound 19533
                                organic polycyclic compound 17307
                                  steroid 14723
                                    hydroxy steroid 14469
                                      3-hydroxy steroid 12808
                                        3beta-hydroxy steroid 2542
                                          3beta-hydroxy-5alpha-cholest-8(14)-en-15-one 1
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