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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:4-\{[4-(dimethylamino)phenyl]diazenyl\}phenyl-beta-lactoside
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Accession:CHEBI:61710 term browser browse the term
Definition:A glycoside comprising beta-lactose having a p-(p-dimethylaminophenylazo)phenyl group at the 1-position.
Synonyms:exact_synonym: 4-{[4-(dimethylamino)phenyl]diazenyl}phenyl beta-D-galactopyranosyl-(1->4)-beta-D-glucopyranoside
 related_synonym: 4-(4-Dimethylaminophenylazo) beta-lactoside;   4-{[4-(dimethylamino)phenyl]diazenyl}phenyl 4-O-beta-D-galactopyranosyl-beta-D-glucopyranoside;   4-{[4-(dimethylamino)phenyl]diazenyl}phenyl beta-D-galactosyl-(1->4)-beta-D-glucoside;   Formula=C26H35N3O11;   InChI=1S/C26H35N3O11/c1-29(2)15-7-3-13(4-8-15)27-28-14-5-9-16(10-6-14)37-25-23(36)21(34)24(18(12-31)39-25)40-26-22(35)20(33)19(32)17(11-30)38-26/h3-10,17-26,30-36H,11-12H2,1-2H3/t17-,18-,19+,20+,21-,22-,23-,24-,25-,26+/m1/s1;   InChIKey=PKTBUSPVTXIOCN-QHIUXXQWSA-N;   SMILES=CN(C)c1ccc(cc1)N=Nc1ccc(O[C@@H]2O[C@H](CO)[C@@H](O[C@@H]3O[C@H](CO)[C@H](O)[C@H](O)[C@H]3O)[C@H](O)[C@H]2O)cc1;   lac dye;   p-(p-dimethylaminophenylazo)-phenyl-beta-lactoside
 xref: CAS:27597-77-9
 xref_mesh: MESH:C009765
 xref: PMID:803530;   Reaxys:72012



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4-\{[4-(dimethylamino)phenyl]diazenyl\}phenyl-beta-lactoside term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 multiple interactions ISO lac dye inhibits the reaction [Dietary Fats results in decreased phosphorylation of AKT1 protein] CTD PMID:36828244 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Dnmt1 DNA methyltransferase 1 decreases activity ISO lac dye results in decreased activity of DNMT1 protein CTD PMID:23839987 NCBI chr 8:19,440,611...19,486,659
Ensembl chr 8:19,440,611...19,486,659
JBrowse link
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit multiple interactions ISO lac dye inhibits the reaction [Dietary Fats results in decreased expression of EZH2 mRNA] CTD PMID:36828244 NCBI chr 4:76,624,399...76,687,362
Ensembl chr 4:76,624,399...76,687,362
JBrowse link
G Foxo1 forkhead box O1 multiple interactions ISO lac dye inhibits the reaction [Dietary Fats results in increased expression of and results in decreased phosphorylation of FOXO1 protein]; lac dye inhibits the reaction [Dietary Fats results in increased expression of FOXO1 mRNA] CTD PMID:36828244 NCBI chr 2:136,312,168...136,390,603
Ensembl chr 2:136,312,168...136,387,790
JBrowse link
G G6pc1 glucose-6-phosphatase catalytic subunit 1 multiple interactions ISO lac dye inhibits the reaction [Dietary Fats results in increased expression of G6PC1 mRNA] CTD PMID:36828244 NCBI chr10:86,307,400...86,318,766
Ensembl chr10:86,257,668...86,333,804
JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions ISO lac dye inhibits the reaction [Dietary Fats results in increased expression of GPT protein] CTD PMID:36828244 NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta multiple interactions ISO lac dye inhibits the reaction [Dietary Fats results in decreased phosphorylation of GSK3B protein] CTD PMID:36828244 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO lac dye inhibits the reaction [Dietary Fats results in increased expression of IL1B mRNA] CTD PMID:36828244 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il6 interleukin 6 multiple interactions ISO lac dye inhibits the reaction [Dietary Fats results in increased expression of IL6 mRNA] CTD PMID:36828244 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Ins1 insulin 1 multiple interactions ISO lac dye inhibits the reaction [Dietary Fats results in increased expression of INS1 protein] CTD PMID:36828244 NCBI chr 1:251,244,973...251,245,540
Ensembl chr 1:251,244,973...251,245,536
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO lac dye inhibits the reaction [Dietary Fats results in increased phosphorylation of MAPK1 protein] CTD PMID:36828244 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO lac dye inhibits the reaction [Dietary Fats results in increased phosphorylation of MAPK3 protein] CTD PMID:36828244 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Pck1 phosphoenolpyruvate carboxykinase 1 multiple interactions ISO lac dye inhibits the reaction [Dietary Fats results in increased expression of PCK1 mRNA] CTD PMID:36828244 NCBI chr 3:161,930,256...161,936,205
Ensembl chr 3:161,930,256...161,936,191
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO lac dye inhibits the reaction [Dietary Fats results in increased phosphorylation of RELA protein] CTD PMID:36828244 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO lac dye inhibits the reaction [Dietary Fats results in increased expression of TNF mRNA] CTD PMID:36828244 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link

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Path 1
Term Annotations click to browse term
  CHEBI ontology 19874
    role 19844
      application 19689
        dye 3004
          4-\{[4-(dimethylamino)phenyl]diazenyl\}phenyl-beta-lactoside 15
Path 2
Term Annotations click to browse term
  CHEBI ontology 19874
    subatomic particle 19872
      composite particle 19872
        hadron 19872
          baryon 19872
            nucleon 19872
              atomic nucleus 19872
                atom 19872
                  main group element atom 19811
                    p-block element atom 19811
                      carbon group element atom 19751
                        carbon atom 19748
                          organic molecular entity 19748
                            heteroorganic entity 19505
                              organochalcogen compound 19268
                                organooxygen compound 19184
                                  carbohydrates and carbohydrate derivatives 15285
                                    carbohydrate 15285
                                      carbohydrate derivative 14300
                                        glycosyl compound 13062
                                          glycoside 11830
                                            4-\{[4-(dimethylamino)phenyl]diazenyl\}phenyl-beta-lactoside 15
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