CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: 4-\{[4-(dimethylamino)phenyl]diazenyl\}phenyl-beta-lactoside
Accession: CHEBI:61710
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Definition: A glycoside comprising beta-lactose having a p-(p-dimethylaminophenylazo)phenyl group at the 1-position.
Synonyms: exact_synonym: 4-{[4-(dimethylamino)phenyl]diazenyl}phenyl beta-D-galactopyranosyl-(1->4)-beta-D-glucopyranoside
related_synonym: 4-(4-Dimethylaminophenylazo) beta-lactoside; 4-{[4-(dimethylamino)phenyl]diazenyl}phenyl 4-O-beta-D-galactopyranosyl-beta-D-glucopyranoside; 4-{[4-(dimethylamino)phenyl]diazenyl}phenyl beta-D-galactosyl-(1->4)-beta-D-glucoside; Formula=C26H35N3O11; InChI=1S/C26H35N3O11/c1-29(2)15-7-3-13(4-8-15)27-28-14-5-9-16(10-6-14)37-25-23(36)21(34)24(18(12-31)39-25)40-26-22(35)20(33)19(32)17(11-30)38-26/h3-10,17-26,30-36H,11-12H2,1-2H3/t17-,18-,19+,20+,21-,22-,23-,24-,25-,26+/m1/s1; InChIKey=PKTBUSPVTXIOCN-QHIUXXQWSA-N; SMILES=CN(C)c1ccc(cc1)N=Nc1ccc(O[C@@H]2O[C@H](CO)[C@@H](O[C@@H]3O[C@H](CO)[C@H](O)[C@H](O)[C@H]3O)[C@H](O)[C@H]2O)cc1; lac dye; p-(p-dimethylaminophenylazo)-phenyl-beta-lactoside
xref: CAS:27597-77-9
xref_mesh: MESH:C009765
xref: PMID:803530; Reaxys:72012
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Akt1
AKT serine/threonine kinase 1
multiple interactions
ISO
lac dye inhibits the reaction [Dietary Fats results in decreased phosphorylation of AKT1 protein]
CTD
PMID:36828244
NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
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Dnmt1
DNA methyltransferase 1
decreases activity
ISO
lac dye results in decreased activity of DNMT1 protein
CTD
PMID:23839987
NCBI chr 8:19,440,611...19,486,659
Ensembl chr 8:19,440,611...19,486,659
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Ezh2
enhancer of zeste 2 polycomb repressive complex 2 subunit
multiple interactions
ISO
lac dye inhibits the reaction [Dietary Fats results in decreased expression of EZH2 mRNA]
CTD
PMID:36828244
NCBI chr 4:76,624,399...76,687,362
Ensembl chr 4:76,624,399...76,687,362
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Foxo1
forkhead box O1
multiple interactions
ISO
lac dye inhibits the reaction [Dietary Fats results in increased expression of and results in decreased phosphorylation of FOXO1 protein]; lac dye inhibits the reaction [Dietary Fats results in increased expression of FOXO1 mRNA]
CTD
PMID:36828244
NCBI chr 2:136,312,168...136,390,603
Ensembl chr 2:136,312,168...136,387,790
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G6pc1
glucose-6-phosphatase catalytic subunit 1
multiple interactions
ISO
lac dye inhibits the reaction [Dietary Fats results in increased expression of G6PC1 mRNA]
CTD
PMID:36828244
NCBI chr10:86,307,400...86,318,766
Ensembl chr10:86,257,668...86,333,804
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Gpt
glutamic--pyruvic transaminase
multiple interactions
ISO
lac dye inhibits the reaction [Dietary Fats results in increased expression of GPT protein]
CTD
PMID:36828244
NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494
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Gsk3b
glycogen synthase kinase 3 beta
multiple interactions
ISO
lac dye inhibits the reaction [Dietary Fats results in decreased phosphorylation of GSK3B protein]
CTD
PMID:36828244
NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
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Il1b
interleukin 1 beta
multiple interactions
ISO
lac dye inhibits the reaction [Dietary Fats results in increased expression of IL1B mRNA]
CTD
PMID:36828244
NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
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Il6
interleukin 6
multiple interactions
ISO
lac dye inhibits the reaction [Dietary Fats results in increased expression of IL6 mRNA]
CTD
PMID:36828244
NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
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Ins1
insulin 1
multiple interactions
ISO
lac dye inhibits the reaction [Dietary Fats results in increased expression of INS1 protein]
CTD
PMID:36828244
NCBI chr 1:251,244,973...251,245,540
Ensembl chr 1:251,244,973...251,245,536
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Mapk1
mitogen activated protein kinase 1
multiple interactions
ISO
lac dye inhibits the reaction [Dietary Fats results in increased phosphorylation of MAPK1 protein]
CTD
PMID:36828244
NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
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Mapk3
mitogen activated protein kinase 3
multiple interactions
ISO
lac dye inhibits the reaction [Dietary Fats results in increased phosphorylation of MAPK3 protein]
CTD
PMID:36828244
NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
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Pck1
phosphoenolpyruvate carboxykinase 1
multiple interactions
ISO
lac dye inhibits the reaction [Dietary Fats results in increased expression of PCK1 mRNA]
CTD
PMID:36828244
NCBI chr 3:161,930,256...161,936,205
Ensembl chr 3:161,930,256...161,936,191
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Rela
RELA proto-oncogene, NF-kB subunit
multiple interactions
ISO
lac dye inhibits the reaction [Dietary Fats results in increased phosphorylation of RELA protein]
CTD
PMID:36828244
NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
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Tnf
tumor necrosis factor
multiple interactions
ISO
lac dye inhibits the reaction [Dietary Fats results in increased expression of TNF mRNA]
CTD
PMID:36828244
NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
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