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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:kuwanone H
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Accession:CHEBI:6147 term browser browse the term
Definition:A tetrahydroxyflavone isolated from the plant species of the genus Morus.
Synonyms:exact_synonym: 8-{(1R,2S,3S)-2-[2,4-dihydroxy-3-(3-methylbut-2-en-1-yl)benzoyl]-2',4'-dihydroxy-5-methyl[1,2,3,6-tetrahydro[1,1'-biphenyl]]-3-yl}-2-(2,4-dihydroxyphenyl)-5,7-dihydroxy-3-(3-methylbut-2-en-1-yl)-4H-1-benzopyran-4-one
 related_synonym: Formula=C45H44O11;   InChI=1S/C45H44O11/c1-21(2)6-10-27-33(48)15-14-29(41(27)53)42(54)38-31(26-12-8-24(46)18-34(26)49)16-23(5)17-32(38)39-36(51)20-37(52)40-43(55)30(11-7-22(3)4)44(56-45(39)40)28-13-9-25(47)19-35(28)50/h6-9,12-15,17-20,31-32,38,46-53H,10-11,16H2,1-5H3/t31-,32-,38-/m0/s1;   InChIKey=DKBPTKFKCCNXNH-QXGWMLRCSA-N;   SMILES=CC(C)=CCc1c(O)ccc(C(=O)[C@H]2[C@@H](CC(C)=C[C@@H]2c2c(O)cc(O)c3c2oc(c(CC=C(C)C)c3=O)-c2ccc(O)cc2O)c2ccc(O)cc2O)c1O
 xref: CAS:76472-87-2;   HMDB:HMDB0030075;   KEGG:C10100;   KNApSAcK:C00001064
 xref_mesh: MESH:C095195
 xref: Reaxys:4640803


show annotations for term's descendants           Sort by:
kuwanone H term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Grp gastrin releasing peptide multiple interactions EXP
ISO		 kuwanon H inhibits the reaction [GRP protein binds to NMBR protein]
kuwanon H inhibits the reaction [GRP protein binds to GRPR protein]		 CTD PMID:7646517 NCBI chr18:59,388,679...59,402,061
Ensembl chr18:59,388,274...59,402,061 		JBrowse link
G Grpr gastrin releasing peptide receptor multiple interactions ISO kuwanon H binds to and results in decreased activity of GRPR protein; kuwanon H inhibits the reaction [GRP protein binds to GRPR protein] CTD PMID:7646517 NCBI chr  X:30,998,425...31,038,442
Ensembl chr  X:30,998,416...31,038,442 		JBrowse link
G Nmbr neuromedin B receptor multiple interactions EXP kuwanon H inhibits the reaction [GRP protein binds to NMBR protein] CTD PMID:7646517 NCBI chr 1:9,115,033...9,146,081
Ensembl chr 1:9,134,889...9,145,462 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19880
    role 19850
      biological role 19848
        biochemical role 19556
          metabolite 19544
            eukaryotic metabolite 19368
              plant metabolite 17985
                kuwanone H 3
Path 2
Term Annotations click to browse term
  CHEBI ontology 19880
    subatomic particle 19878
      composite particle 19878
        hadron 19878
          baryon 19878
            nucleon 19878
              atomic nucleus 19878
                atom 19878
                  main group element atom 19817
                    p-block element atom 19817
                      carbon group element atom 19757
                        carbon atom 19754
                          organic molecular entity 19754
                            organic molecule 19706
                              organic cyclic compound 19495
                                organic heterocyclic compound 18874
                                  oxacycle 17906
                                    benzopyran 11972
                                      1-benzopyran 11726
                                        flavonoid 7226
                                          anthoxanthin 4585
                                            flavones 4585
                                              hydroxyflavone 4562
                                                tetrahydroxyflavone 742
                                                  kuwanone H 3
paths to the root