The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
A member of the class of quinazolines that is quinazoline-2,4(1H,3H)-dione which is substituted at position 3 by a 2-[4-(p-fluorobenzoyl)piperidin-1-yl]ethyl group.
[[Ketanserin inhibits the reaction [Serotonin results in increased activity of AKT1 protein]] promotes the reaction [Serotonin inhibits the reaction [IRS1 protein binds to YWHAB protein]]] which results in increased ubiquitination of and results in increased degradation of IRS1 protein; [Ketanserin inhibits the reaction [Serotonin results in increased activity of AKT1 protein]] promotes the reaction [Serotonin inhibits the reaction [IRS1 protein binds to YWHAB protein]]; Ketanserin inhibits the reaction [Serotonin results in increased activity of AKT1 protein]
Aripiprazole inhibits the reaction [Ketanserin binds to HTR2A protein]; Clozapine inhibits the reaction [Ketanserin binds to HTR2A protein]; Ketanserin binds to and results in decreased activity of HTR2A protein; N-Methyl-3,4-methylenedioxyamphetamine inhibits the reaction [Ketanserin binds to HTR2A protein]; Quetiapine Fumarate inhibits the reaction [Ketanserin binds to HTR2A protein]; Spiperone inhibits the reaction [Ketanserin binds to HTR2A protein]; ziprasidone inhibits the reaction [Ketanserin binds to HTR2A protein] Ketanserin results in decreased activity of HTR2A protein 8-fluoro-12-(4-methylpiperazin-1-yl)-6H-(1)benzothieno(2,3-b)(1,5)benzodiazepine inhibits the reaction [Ketanserin binds to HTR2A protein]; [Ketanserin binds to and results in decreased activity of HTR2A protein] inhibits the reaction [Methamphetamine results in decreased abundance of Serotonin]; [Ketanserin binds to and results in decreased activity of HTR2A protein] inhibits the reaction [Methamphetamine results in increased secretion of Corticosterone]; [Ketanserin binds to and results in decreased activity of HTR2A protein] which results in decreased susceptibility to Serotonin; Diazinon promotes the reaction [Ketanserin binds to HTR2A protein]; Ketanserin binds to and results in decreased activity of HTR2A protein; Ketanserin inhibits the reaction [[4-iodo-2,5-dimethoxyphenylisopropylamine binds to and results in increased activity of HTR2A protein] which results in increased secretion of and results in increased abundance of Dopamine]; Ketanserin inhibits the reaction [Cocaine promotes the reaction [[4-iodo-2,5-dimethoxyphenylisopropylamine binds to and results in increased activity of HTR2A protein] which results in increased secretion of and results in increased abundance of Dopamine]]; Ketanserin inhibits the reaction [Tramadol results in increased activity of HTR2A protein]; Risperidone inhibits the reaction [Ketanserin binds to HTR2A protein] 4-iodo-2,5-dimethoxyphenylisopropylamine inhibits the reaction [Ketanserin binds to HTR2A protein]; cyclohexyl carbamic acid 3'-carbamoylbiphenyl-3-yl ester inhibits the reaction [Ketanserin binds to HTR2A protein]; HU 211 inhibits the reaction [Ketanserin binds to HTR2A protein]; Ketanserin binds to and results in decreased activity of HTR2A protein
[Ketanserin binds to and results in decreased activity of HTR7 protein] inhibits the reaction [5-carboxamidotryptamine results in increased abundance of Cyclic AMP]
[[Ketanserin inhibits the reaction [Serotonin results in increased activity of AKT1 protein]] promotes the reaction [Serotonin inhibits the reaction [IRS1 protein binds to YWHAB protein]]] which results in increased ubiquitination of and results in increased degradation of IRS1 protein; [Ketanserin inhibits the reaction [Serotonin results in increased activity of AKT1 protein]] promotes the reaction [Serotonin inhibits the reaction [IRS1 protein binds to YWHAB protein]]
[[Ketanserin inhibits the reaction [Serotonin results in increased activity of AKT1 protein]] promotes the reaction [Serotonin inhibits the reaction [IRS1 protein binds to YWHAB protein]]] which results in increased ubiquitination of and results in increased degradation of IRS1 protein; [Ketanserin inhibits the reaction [Serotonin results in increased activity of AKT1 protein]] promotes the reaction [Serotonin inhibits the reaction [IRS1 protein binds to YWHAB protein]]