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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:metalaxyl-M
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Accession:CHEBI:60607 term browser browse the term
Definition:A methyl N-(2,6-dimethylphenyl)-N-(methoxyacetyl)alaninate that is the more active R-enantiomer of metalaxyl. A systemic fungicide, it is active against phytopathogens of the order Peronosporales and is used to conrtrol Pythium in a number of vegetable crops.
Synonyms:exact_synonym: methyl N-(2,6-dimethylphenyl)-N-(methoxyacetyl)-D-alaninate
 related_synonym: (-)-metalaxyl;   (R)-N-(2,6-dimethylphenyl)-N-(methoxyacetylamino)propionic acid methyl ester;   Formula=C15H21NO4;   InChI=1S/C15H21NO4/c1-10-7-6-8-11(2)14(10)16(13(17)9-19-4)12(3)15(18)20-5/h6-8,12H,9H2,1-5H3/t12-/m1/s1;   InChIKey=ZQEIXNIJLIKNTD-GFCCVEGCSA-N;   R-metalaxyl;   SMILES=COCC(=O)N([C@H](C)C(=O)OC)c1c(C)cccc1C;   mefenoxam;   methyl (R)-2-{[(2,6-dimethylphenyl)methoxyacetyl]amino} propionate;   methyl (R)-N-(2,6-dimethylphenyl)-N-(methoxyacetyl)alaninate;   methyl N-(methoxyacetyl)-N-(2,6-xylyl)-D-alaninate
 xref: AGR:IND44452872;   CAS:70630-17-0;   KEGG:C18626;   PMID:19809773;   PMID:20582630;   PMID:21174493;   PMID:21272886;   PMID:21315406;   PMID:21322247;   PMID:21712597;   PPDB:445;   Patent:WO2011012493;   Pesticides:metalaxyl-m;   Reaxys:5081553
 cyclic_relationship: is_enantiomer_of CHEBI:82791



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metalaxyl term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp2c6 cytochrome P450, family 2, subfamily C, polypeptide 6 decreases expression ISO metalaxyl results in decreased expression of CYP2C19 protein CTD PMID:32194361 NCBI chr 1:237,938,521...237,976,238
Ensembl chr 1:237,693,094...238,057,596
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G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 decreases expression ISO metalaxyl results in decreased expression of CYP7A1 protein CTD PMID:32194361 NCBI chr 5:19,376,979...19,386,676
Ensembl chr 5:19,376,974...19,386,688
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Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19915
    role 19885
      application 19727
        agrochemical 16868
          metalaxyl-M 2
            metalaxyl 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19915
    subatomic particle 19913
      composite particle 19895
        hadron 19895
          baryon 19913
            nucleon 19895
              atomic nucleus 19913
                atom 19895
                  main group element atom 19852
                    p-block element atom 19834
                      carbon group element atom 19774
                        carbon atom 19770
                          organic molecular entity 19770
                            heteroorganic entity 19542
                              organochalcogen compound 19302
                                organooxygen compound 19218
                                  carbon oxoacid 18664
                                    carboxylic acid 18661
                                      monocarboxylic acid 18025
                                        fatty acid 16833
                                          saturated fatty acid 16569
                                            propionic acid 3875
                                              alanine 116
                                                alanine derivative 114
                                                  methyl N-(2,6-dimethylphenyl)-N-(methoxyacetyl)alaninate 2
                                                    metalaxyl-M 2
                                                      metalaxyl 2
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