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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:benzyl ether
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Accession:CHEBI:59859 term browser browse the term
Definition:A compound of formula PhCH2OR (R =/= H).
Synonyms:related_synonym: benzyl ethers;   benzylic ether;   benzylic ethers



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(Dimethoxymethyl)benzene term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ar androgen receptor multiple interactions ISO alpha,alpha-dimethoxytoluene inhibits the reaction [Metribolone results in increased activity of AR protein] CTD PMID:18324785 NCBI chr  X:67,135,317...67,304,476
Ensembl chr  X:67,135,317...67,304,467
JBrowse link
monobenzone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Afp alpha-fetoprotein affects binding EXP monobenzone binds to AFP protein CTD PMID:23013281 NCBI chr14:17,857,584...17,875,645
Ensembl chr14:17,857,584...17,875,649
JBrowse link
G Ar androgen receptor affects binding EXP monobenzone binds to AR protein CTD PMID:14565775 NCBI chr  X:67,135,317...67,304,476
Ensembl chr  X:67,135,317...67,304,467
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 multiple interactions ISO [monobenzone results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA CTD PMID:25455453 NCBI chr12:14,321,771...14,343,886
Ensembl chr12:14,321,771...14,343,857
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 increases activity
multiple interactions
ISO monobenzone results in increased activity of NR1I2 protein
[monobenzone results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA
CTD PMID:25455453 NCBI chr11:75,965,717...76,006,733
Ensembl chr11:75,965,632...76,002,380
JBrowse link
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO monobenzone inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr 1:50,668,817...50,711,019
Ensembl chr 1:50,668,817...50,711,019
JBrowse link
G Tp53 tumor protein p53 affects activity ISO monobenzone affects the activity of TP53 protein CTD PMID:35435491 NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20862
    chemical entity 20860
      atom 20860
        nonmetal atom 20766
          oxygen atom 20457
            oxygen molecular entity 20457
              organooxygen compound 19806
                ether 17649
                  benzyl ether 6
                    (+/-)-tylopilusin A 0
                    (2R,4S)-6,6-dimethoxy-1-phenylmethoxyhexane-2,4-diol 0
                    (4-Methylphenyl) methanol, neopentyl ether 0
                    (7R)-(-)-methoxysydonol 0
                    (Dimethoxymethyl)benzene 1
                    1,4-Bis(chloromethoxymethyl)benzene 0
                    1-(propan-2-ylamino)-3-[4-(2-propan-2-yloxyethoxymethyl)phenoxy]-2-propanol 0
                    1-Hexene, 6-phenyl-4-(1-phenylethoxy)- 0
                    1-O-methylterricolyne 0
                    1-[5-t-butyl-2-(4-methylphenyl)pyrazol-3-yl]-3-[4-(2-phenylmethoxyethyl)-1,3-thiazol-2-yl]urea 0
                    17-bromo-30-methyloscillatoxin D 0
                    2-(3-methyl-2-buten-1-yl)-4-methoxyethyl-phenol 0
                    2-(Ethoxymethyl)phenol 0
                    2-Ethoxy-4-(methoxymethyl)phenol 0
                    2-[(2-bromo-6-fluorobenzyl)oxy]-1-methyl-4-(propan-2-yl)-7-oxabicyclo[2.2.1]heptane + 0
                    4-(Butoxymethyl)phenol 0
                    4-(Ethoxymethyl)phenol 0
                    4-Benzyloxybenzyl alcohol 0
                    5-(3-phenylmethoxypropyl)-1H-imidazole 0
                    5-[(3-phenylmethoxy-1-piperidinyl)methyl]-3-(phenylmethyl)-1,2,4-oxadiazole 0
                    5-benzyloxybenzylacyclouridine 0
                    8-Zinniol 2-(phenyl)ethyl ether 0
                    8-Zinniol methyl ether 0
                    8-methoxy-9-O-isobutyrylthymol 0
                    Acetic acid, methoxyphenyl-, methyl ester 0
                    Aspergentisyl B 0
                    Australeol C 0
                    Benzyl butyl ether 0
                    Benzyl ethyl ether 0
                    DL-alpha-Methoxyphenylacetic acid 0
                    Dothiorelone F 0
                    FPR A14 0
                    Flupoxam 0
                    Ganotheaecoloid J 0
                    LLP-3 0
                    Lucidulactone B 0
                    Neo-debromoaplysiatoxin A 0
                    Neo-debromoaplysiatoxin B 0
                    Neo-debromoaplysiatoxin D 0
                    Neo-debromoaplysiatoxin E 0
                    Neo-debromoaplysiatoxin F 0
                    Nhatrangin A 0
                    Nhatrangin B 0
                    Obscurolide A4 0
                    Obscurolide-B4 0
                    Oscillatoxin E 0
                    Oscillatoxin F 0
                    Oscillatoxin H 0
                    Rivenprost 0
                    Terrestrol C 0
                    ZM 323881 0
                    [(2R)-4-(Benzyloxy)-2-methylbutoxy](2-methyl-2-propanyl)diphenylsilane 0
                    [2-Bromo-1-(trifluoromethoxy)ethyl]benzene 0
                    amixetrine 0
                    beta-O-Methylynephrine 0
                    ciclonium 0
                    dibenzyl ether 0
                    eprozinol 0
                    ethyl 2-[5-benzyloxy-4'-(trifluoromethyl)biphenyl-3-yl]pentanoate 0
                    ethyl [5-benzyloxy-4'-(trifluoromethyl)biphenyl-3-yl]acetate 0
                    monobenzone 6
                    myrophine + 0
                    para-Anisaldehyde diethyl acetal 0
                    sparsentan 0
                    zipeprol 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 20862
    subatomic particle 20860
      composite particle 20860
        hadron 20860
          baryon 20860
            nucleon 20860
              atomic nucleus 20860
                atom 20860
                  main group element atom 20781
                    p-block element atom 20781
                      carbon group element atom 20715
                        carbon atom 20710
                          organic molecular entity 20710
                            heteroorganic entity 20219
                              organochalcogen compound 19904
                                organooxygen compound 19806
                                  ether 17649
                                    benzyl ether 6
                                      (+/-)-tylopilusin A 0
                                      (2R,4S)-6,6-dimethoxy-1-phenylmethoxyhexane-2,4-diol 0
                                      (4-Methylphenyl) methanol, neopentyl ether 0
                                      (7R)-(-)-methoxysydonol 0
                                      (Dimethoxymethyl)benzene 1
                                      1,4-Bis(chloromethoxymethyl)benzene 0
                                      1-(propan-2-ylamino)-3-[4-(2-propan-2-yloxyethoxymethyl)phenoxy]-2-propanol 0
                                      1-Hexene, 6-phenyl-4-(1-phenylethoxy)- 0
                                      1-O-methylterricolyne 0
                                      1-[5-t-butyl-2-(4-methylphenyl)pyrazol-3-yl]-3-[4-(2-phenylmethoxyethyl)-1,3-thiazol-2-yl]urea 0
                                      17-bromo-30-methyloscillatoxin D 0
                                      2-(3-methyl-2-buten-1-yl)-4-methoxyethyl-phenol 0
                                      2-(Ethoxymethyl)phenol 0
                                      2-Ethoxy-4-(methoxymethyl)phenol 0
                                      2-[(2-bromo-6-fluorobenzyl)oxy]-1-methyl-4-(propan-2-yl)-7-oxabicyclo[2.2.1]heptane + 0
                                      4-(Butoxymethyl)phenol 0
                                      4-(Ethoxymethyl)phenol 0
                                      4-Benzyloxybenzyl alcohol 0
                                      5-(3-phenylmethoxypropyl)-1H-imidazole 0
                                      5-[(3-phenylmethoxy-1-piperidinyl)methyl]-3-(phenylmethyl)-1,2,4-oxadiazole 0
                                      5-benzyloxybenzylacyclouridine 0
                                      8-Zinniol 2-(phenyl)ethyl ether 0
                                      8-Zinniol methyl ether 0
                                      8-methoxy-9-O-isobutyrylthymol 0
                                      Acetic acid, methoxyphenyl-, methyl ester 0
                                      Aspergentisyl B 0
                                      Australeol C 0
                                      Benzyl butyl ether 0
                                      Benzyl ethyl ether 0
                                      DL-alpha-Methoxyphenylacetic acid 0
                                      Dothiorelone F 0
                                      FPR A14 0
                                      Flupoxam 0
                                      Ganotheaecoloid J 0
                                      LLP-3 0
                                      Lucidulactone B 0
                                      Neo-debromoaplysiatoxin A 0
                                      Neo-debromoaplysiatoxin B 0
                                      Neo-debromoaplysiatoxin D 0
                                      Neo-debromoaplysiatoxin E 0
                                      Neo-debromoaplysiatoxin F 0
                                      Nhatrangin A 0
                                      Nhatrangin B 0
                                      Obscurolide A4 0
                                      Obscurolide-B4 0
                                      Oscillatoxin E 0
                                      Oscillatoxin F 0
                                      Oscillatoxin H 0
                                      Rivenprost 0
                                      Terrestrol C 0
                                      ZM 323881 0
                                      [(2R)-4-(Benzyloxy)-2-methylbutoxy](2-methyl-2-propanyl)diphenylsilane 0
                                      [2-Bromo-1-(trifluoromethoxy)ethyl]benzene 0
                                      amixetrine 0
                                      beta-O-Methylynephrine 0
                                      ciclonium 0
                                      dibenzyl ether 0
                                      eprozinol 0
                                      ethyl 2-[5-benzyloxy-4'-(trifluoromethyl)biphenyl-3-yl]pentanoate 0
                                      ethyl [5-benzyloxy-4'-(trifluoromethyl)biphenyl-3-yl]acetate 0
                                      monobenzone 6
                                      myrophine + 0
                                      para-Anisaldehyde diethyl acetal 0
                                      sparsentan 0
                                      zipeprol 0
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