amino fatty acid - Ontology Report - Rat Genome Database

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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:	amino fatty acid	go back to main search page
Accession:	CHEBI:59650	browse the term
Definition:	A fatty acid containing at least one amino substituent.
Synonyms:	related_synonym:	amino FA; amino fatty acids; carboxylated base; carboxylated bases; lipoamino acid; lipoamino acids
	cyclic_relationship:	is_conjugate_acid_of CHEBI:61007

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Rat (19) Mouse (19) Human (19) Chinchilla (0) Bonobo (0) Dog (0) Squirrel (0) Pig (0) Green Monkey (0) Naked Mole-rat (0) All
Genes (19)

6-aminohexanoic acid

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

alpha-2-macroglobulin

decreases expression

Aminocaproic Acid results in decreased expression of A2M protein

NCBI chr 4:154,897,770...154,947,787
Ensembl chr 4:154,897,877...154,947,786

G

folate hydrolase 1

multiple interactions

[2-(3-(1,3-dicarboxypropyl)ureido)pentanedioic acid binds to Aminocaproic Acid binds to 1-(1,3-carboxypropyl)-4,7-carboxymethyl-1,4,7-triazacyclononane binds to Valerates binds to bombesin (7-14) binds to Copper] inhibits the reaction [isospaglumic acid binds to FOLH1 protein]

NCBI chr 1:140,428,101...140,501,563
Ensembl chr 1:140,428,101...140,501,379

G

gastrin releasing peptide receptor

multiple interactions

[2-(3-(1,3-dicarboxypropyl)ureido)pentanedioic acid binds to Aminocaproic Acid binds to 1-(1,3-carboxypropyl)-4,7-carboxymethyl-1,4,7-triazacyclononane binds to Valerates binds to bombesin (7-14) binds to Copper] inhibits the reaction [bombesin, Tyr(4)- binds to GRPR protein]

NCBI chr X:30,998,425...31,038,442
Ensembl chr X:30,998,416...31,038,442

G

mitogen activated protein kinase 1

multiple interactions

Aminocaproic Acid inhibits the reaction [PLG protein results in increased phosphorylation of MAPK1 protein]

NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616

G

mitogen activated protein kinase 3

multiple interactions

Aminocaproic Acid inhibits the reaction [PLG protein results in increased phosphorylation of MAPK3 protein]

NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863

G

plasminogen

multiple interactions

Aminocaproic Acid inhibits the reaction [PLG protein results in increased phosphorylation of MAPK1 protein]; Aminocaproic Acid inhibits the reaction [PLG protein results in increased phosphorylation of MAPK3 protein]

NCBI chr 1:48,325,186...48,367,643
Ensembl chr 1:48,325,185...48,367,786

G

serpin family C member 1

increases expression

Aminocaproic Acid results in increased expression of SERPINC1 protein

NCBI chr13:73,257,208...73,271,476
Ensembl chr13:73,257,179...73,284,293

myriocin

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

acetyl-CoA carboxylase alpha

multiple interactions

thermozymocidin inhibits the reaction [Dexamethasone results in increased expression of ACACA mRNA]

NCBI chr10:69,014,261...69,276,453
Ensembl chr10:69,014,170...69,276,457

G

angiopoietin-like 4

increases expression

thermozymocidin results in increased expression of ANGPTL4 mRNA

NCBI chr 7:14,550,288...14,557,797
Ensembl chr 7:14,550,311...14,556,519

G

caspase 3

multiple interactions

thermozymocidin inhibits the reaction [Dronabinol results in increased activity of CASP3 protein]; thermozymocidin inhibits the reaction [gamma-Tocopherol results in increased activity of CASP3 protein]

PMID:15596715 PMID:16818650

NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648

G

DNA-damage inducible transcript 3

multiple interactions

thermozymocidin inhibits the reaction [fumonisin B1 results in increased expression of DDIT3 protein]; thermozymocidin inhibits the reaction [Resveratrol results in increased expression of DDIT3 protein]

PMID:24264887 PMID:31891755

NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201

G

Fas cell surface death receptor

multiple interactions

thermozymocidin inhibits the reaction [[sorafenib co-treated with vorinostat] affects the localization of and results in increased activity of FAS protein]

NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591

G

fatty acid synthase

multiple interactions

[thermozymocidin results in increased susceptibility to Dexamethasone] which results in decreased expression of FASN mRNA

NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261

G

heat shock protein family A (Hsp70) member 5

multiple interactions

thermozymocidin inhibits the reaction [fumonisin B1 results in increased expression of HSPA5 protein]

NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891

G

microtubule-associated protein 1 light chain 3 beta

multiple interactions

thermozymocidin inhibits the reaction [Dronabinol results in increased expression of and affects the localization of and affects the lipidation of MAP1LC3B protein]

NCBI chr19:49,665,795...49,673,655
Ensembl chr19:49,665,791...49,677,690
Ensembl chr16:49,665,791...49,677,690

G

nuclear protein 1, transcriptional regulator

multiple interactions

thermozymocidin inhibits the reaction [Dronabinol results in increased expression of NUPR1 mRNA]

PMID:16616335 PMID:16818650

NCBI chr 1:181,213,292...181,215,327
Ensembl chr 1:181,213,368...181,215,281

G

ornithine decarboxylase 1

multiple interactions

thermozymocidin inhibits the reaction [resveratrol results in decreased activity of ODC1 protein]

NCBI chr 6:40,329,831...40,336,444
Ensembl chr 6:40,329,964...40,336,440

G

poly (ADP-ribose) polymerase 1

multiple interactions

thermozymocidin inhibits the reaction [resveratrol results in increased cleavage of PARP1 protein]

NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404

G

protein kinase C, zeta

decreases activity

thermozymocidin results in decreased activity of PRKCZ protein

NCBI chr 5:165,817,786...165,930,386
Ensembl chr 5:165,819,466...165,930,367

Term paths to the root

Path 1
Term	Annotations
CHEBI ontology	19874
role	19844
application	19689
NMR chemical shift reference compound	18065
ammonia	17865
organic amino compound	17865
amine	8298
amino fatty acid	19
4-[4-phenyl-3,6-dihydro-1(2H)-pyridinyl]butanoic acid hydrochloride	0
7,8-diaminononanoic acid +	0
alpha-amino fatty acid +	12
beta-amino-fatty acid +	0
omega-amino fatty acid +	7
Path 2
Term	Annotations
CHEBI ontology	19874
subatomic particle	19872
composite particle	19872
hadron	19872
baryon	19872
nucleon	19872
atomic nucleus	19872
atom	19872
main group element atom	19811
p-block element atom	19811
carbon group element atom	19751
carbon atom	19748
organic molecular entity	19748
heteroorganic entity	19505
organochalcogen compound	19268
organooxygen compound	19184
carbon oxoacid	18654
carboxylic acid	18651
monocarboxylic acid	18000
fatty acid	16833
nitrogen-containing fatty acid	19
amino fatty acid	19
4-[4-phenyl-3,6-dihydro-1(2H)-pyridinyl]butanoic acid hydrochloride	0
7,8-diaminononanoic acid +	0
alpha-amino fatty acid +	12
beta-amino-fatty acid +	0
omega-amino fatty acid +	7

paths to the root