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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:mesoporphyrins
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Accession:CHEBI:59559 term browser browse the term
Definition:Any porphyrin compound produced from a protoporphyrin by the addition of a hydrogen to the double bond of each of the vinyl groups.
Synonyms:xref_mesh: MESH:D008652


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mesoporphyrin IX term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Crh corticotropin releasing hormone multiple interactions ISO mesoporphyrin IX analog inhibits the reaction [Hemin results in increased secretion of CRH protein] CTD PMID:11232018 NCBI chr 2:102,143,055...102,144,919
Ensembl chr 2:102,143,055...102,144,919 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions ISO mesoporphyrin IX inhibits the reaction [methylmercuric chloride inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein]]; mesoporphyrin IX promotes the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein] CTD PMID:36245390 NCBI chr 8:66,991,940...66,998,014
Ensembl chr 8:58,096,077...58,102,125 		JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions ISO [mesoporphyrin IX binds to HPX protein] which results in increased expression of HMOX1 mRNA; hexamethylene bisacetamide inhibits the reaction [[mesoporphyrin IX binds to HPX protein] which results in increased expression of HMOX1 mRNA] CTD PMID:12042074 NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Hpx hemopexin multiple interactions ISO [mesoporphyrin IX binds to HPX protein] which results in increased expression of HMOX1 mRNA; [mesoporphyrin IX binds to HPX protein] which results in increased expression of MT1 mRNA; [mesoporphyrin IX binds to HPX protein] which results in increased expression of MT2 mRNA; hexamethylene bisacetamide inhibits the reaction [[mesoporphyrin IX binds to HPX protein] which results in increased expression of HMOX1 mRNA]; hexamethylene bisacetamide promotes the reaction [[mesoporphyrin IX binds to HPX protein] which results in increased expression of MT1 mRNA]; hexamethylene bisacetamide promotes the reaction [[mesoporphyrin IX binds to HPX protein] which results in increased expression of MT2 mRNA] CTD PMID:12042074 NCBI chr 1:159,932,819...159,940,327
Ensembl chr 1:159,932,755...159,940,328 		JBrowse link
G Mt1 metallothionein 1 multiple interactions ISO [mesoporphyrin IX binds to HPX protein] which results in increased expression of MT1 mRNA; hexamethylene bisacetamide promotes the reaction [[mesoporphyrin IX binds to HPX protein] which results in increased expression of MT1 mRNA] CTD PMID:12042074 NCBI chr19:10,826,032...10,827,048
Ensembl chr19:10,826,032...10,827,049
Ensembl chr17:10,826,032...10,827,049
Ensembl chr  X:10,826,032...10,827,049 		JBrowse link
G Mt2 metallothionein 2 multiple interactions ISO [mesoporphyrin IX binds to HPX protein] which results in increased expression of MT2 mRNA; hexamethylene bisacetamide promotes the reaction [[mesoporphyrin IX binds to HPX protein] which results in increased expression of MT2 mRNA] CTD PMID:12042074 NCBI chr19:10,832,009...10,832,783
Ensembl chr19:10,832,002...10,832,784 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19899
    role 19870
      biological role 19868
        biochemical role 19579
          cofactor 16600
            porphyrins 386
              mesoporphyrins 6
                N-methylmesoporphyrin 0
                N-methylmesoporphyrin(2-) 0
                mesoporphyrin IX 6
Path 2
Term Annotations click to browse term
  CHEBI ontology 19899
    subatomic particle 19897
      composite particle 19897
        hadron 19897
          baryon 19897
            nucleon 19897
              atomic nucleus 19897
                atom 19897
                  main group element atom 19836
                    p-block element atom 19836
                      carbon group element atom 19776
                        carbon atom 19772
                          organic molecular entity 19772
                            organic molecule 19725
                              organic cyclic compound 19517
                                organic heterocyclic compound 18894
                                  organonitrogen heterocyclic compound 18178
                                    polypyrrole 710
                                      tetrapyrrole 597
                                        cyclic tetrapyrrole 468
                                          porphyrins 386
                                            mesoporphyrins 6
                                              N-methylmesoporphyrin 0
                                              N-methylmesoporphyrin(2-) 0
                                              mesoporphyrin IX 6
paths to the root