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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:iodoquinol
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Accession:CHEBI:5950 term browser browse the term
Definition:A monohydroxyquinoline that is quinolin-8-ol in which the hydrogens at positions 5 and 7 are replaced by iodine. It is considered the drug of choice for treating asymptomatic or moderate forms of amoebiasis.
Synonyms:exact_synonym: 5,7-diiodoquinolin-8-ol
 related_synonym: 5,7-diiodo-8-hydroxyquinoline;   5,7-diiodo-8-quinolinol;   8-hydroxy-5,7-diiodoquinoline;   Diamoebin;   Diodoquine;   Diodoxylin;   Diquinol;   Direxiode;   Dyodin;   Embequin;   Enterosept;   Floraquin;   Fluoraquin;   Formula=C9H5I2NO;   InChI=1S/C9H5I2NO/c10-6-4-7(11)9(13)8-5(6)2-1-3-12-8/h1-4,13H;   InChIKey=UXZFQZANDVDGMM-UHFFFAOYSA-N;   Ioquin;   Lanodoxin;   Moebiquin;   Panaquin;   Quinadome;   Rafamebin;   SMILES=OC1=C2N=CC=CC2=C(I)C=C1I;   SS 578;   Searlequin;   Sebaquin;   Yodoxin;   Zoaquin;   di-iodohydroxyquinoline;   diiodohidroxiquinoleina;   diiodohydroxyquin;   diiodohydroxyquinoleine;   diiodohydroxyquinoline;   diiodohydroxyquinolinum;   diiodoquin;   diiodoquinol
 xref: CAS:83-73-8;   Chemspider:3597;   DrugBank:DB09115;   Drug_Central:1457;   KEGG:C07636;   KEGG:D00581;   LINCS:LSM-25652
 xref_mesh: MESH:D004103
 xref: PMID:1090898;   PMID:122845;   PMID:126030;   PMID:13513741;   PMID:13568180;   PMID:13867524;   PMID:14493155;   PMID:19055171;   PMID:2146587;   PMID:22650;   PMID:24035940;   PMID:24533282;   PMID:2493578;   PMID:27449410;   PMID:29438107;   PMID:30895611;   PMID:3104778;   PMID:31141575;   PMID:321481;   PMID:32253206;   PMID:32473310;   PMID:329460;   PMID:33052959;   PMID:4276320;   PMID:4608821;   PMID:4874115;   PMID:4893942;   PMID:6783511;   PMID:8067755;   PMID:8433407;   PMID:9408854;   Reaxys:153639;   Wikipedia:Diiodohydroxyquinoline



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iodoquinol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gstp1 glutathione S-transferase pi 1 multiple interactions ISO Iodoquinol inhibits the reaction [GSTP1 protein results in increased metabolism of 1-chloro-2,4-dinitrobenzene-glutathione conjugate] CTD PMID:23769903 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226
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  CHEBI ontology 19880
    role 19850
      biological role 19848
        antimicrobial agent 18250
          antibacterial agent 16369
            iodoquinol 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19880
    subatomic particle 19878
      composite particle 19878
        hadron 19878
          baryon 19878
            nucleon 19878
              atomic nucleus 19878
                atom 19878
                  main group element atom 19817
                    p-block element atom 19817
                      carbon group element atom 19757
                        carbon atom 19754
                          organic molecular entity 19754
                            organic molecule 19706
                              organic cyclic compound 19495
                                organic heterocyclic compound 18874
                                  organonitrogen heterocyclic compound 18153
                                    quinolines 2658
                                      hydroxyquinoline 331
                                        monohydroxyquinoline 328
                                          iodoquinol 1
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