|
G |
Ahr |
aryl hydrocarbon receptor |
multiple interactions increases response to substance |
ISO |
[AHR protein results in increased susceptibility to Antigens] which results in increased secretion of IFNG protein; [AHR protein results in increased susceptibility to Antigens] which results in increased secretion of IL13 protein; [AHR protein results in increased susceptibility to Antigens] which results in increased secretion of IL4 protein; Cyclosporine inhibits the reaction [[AHR protein results in increased susceptibility to Antigens] which results in increased susceptibility to Methacholine Chloride]; Cyclosporine inhibits the reaction [AHR protein results in increased susceptibility to Antigens] [AHR protein results in increased susceptibility to Antigens] which results in increased susceptibility to Methacholine Chloride; AHR protein results in increased susceptibility to Antigens |
CTD |
PMID:27869817 |
|
NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
|
|
G |
Akt1 |
AKT serine/threonine kinase 1 |
increases phosphorylation multiple interactions |
ISO |
Antigens results in increased phosphorylation of AKT1 protein Quinoxalines analog inhibits the reaction [Antigens results in increased phosphorylation of AKT1 protein] |
CTD |
PMID:21958720 |
|
NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
|
|
G |
Cldn3 |
claudin 3 |
multiple interactions |
ISO |
[deoxynivalenol results in increased susceptibility to Antigens] which results in decreased expression of CLDN3 mRNA; [ochratoxin A results in increased susceptibility to Antigens] which results in decreased expression of CLDN3 mRNA |
CTD |
PMID:28935500 |
|
NCBI chr12:21,708,538...21,710,010
Ensembl chr12:21,708,398...21,711,001
|
|
G |
Fyn |
FYN proto-oncogene, Src family tyrosine kinase |
increases activity multiple interactions |
ISO |
Antigens results in increased activity of FYN protein Quinoxalines analog inhibits the reaction [Antigens results in increased activity of FYN protein] |
CTD |
PMID:21958720 |
|
NCBI chr20:42,767,733...42,960,903
Ensembl chr20:42,766,369...42,959,911
|
|
G |
Ifng |
interferon gamma |
multiple interactions increases secretion |
ISO |
[zafirlukast co-treated with Prednisone co-treated with Budesonide] inhibits the reaction [Antigens results in increased secretion of IFNG protein] [AHR protein results in increased susceptibility to Antigens] which results in increased secretion of IFNG protein; [deoxynivalenol results in increased susceptibility to Antigens] which results in increased expression of IFNG protein; [Dronabinol inhibits the reaction [Antigens results in increased expression of MIR21A mRNA]] which results in decreased expression of IFNG mRNA; [ochratoxin A results in increased susceptibility to Antigens] which results in increased expression of IFNG protein |
CTD |
PMID:16160912 PMID:27038180 PMID:27869817 PMID:28935500 |
|
NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
|
|
G |
Il13 |
interleukin 13 |
increases secretion multiple interactions |
ISO |
Antigens results in increased secretion of IL13 protein [AHR protein results in increased susceptibility to Antigens] which results in increased secretion of IL13 protein |
CTD |
PMID:16160912 PMID:27869817 |
|
NCBI chr10:37,790,130...37,792,687
Ensembl chr10:37,790,130...37,792,737
|
|
G |
Il17a |
interleukin 17A |
multiple interactions increases expression |
ISO |
[deoxynivalenol results in increased susceptibility to Antigens] which results in increased expression of IL17A protein; [ochratoxin A results in increased susceptibility to Antigens] which results in increased expression of IL17A protein Antigens results in increased expression of IL17A protein |
CTD |
PMID:27038180 PMID:28935500 |
|
NCBI chr 9:23,144,402...23,147,889
Ensembl chr 9:23,144,402...23,147,889
|
|
G |
Il1b |
interleukin 1 beta |
multiple interactions |
ISO |
[deoxynivalenol results in increased susceptibility to Antigens] which results in increased expression of IL1B protein; [ochratoxin A results in increased susceptibility to Antigens] which results in increased expression of IL1B protein |
CTD |
PMID:28935500 |
|
NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
|
|
G |
Il4 |
interleukin 4 |
increases expression multiple interactions increases secretion |
ISO |
Antigens results in increased expression of IL4 mRNA [AHR protein results in increased susceptibility to Antigens] which results in increased secretion of IL4 protein; Quinoxalines analog inhibits the reaction [Antigens results in increased expression of IL4 mRNA]; Quinoxalines analog inhibits the reaction [Antigens results in increased secretion of IL4 protein] |
CTD |
PMID:21958720 PMID:27869817 |
|
NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
|
|
G |
Il6 |
interleukin 6 |
multiple interactions |
ISO |
[deoxynivalenol results in increased susceptibility to Antigens] which results in increased expression of IL6 protein; [ochratoxin A results in increased susceptibility to Antigens] which results in increased expression of IL6 protein |
CTD |
PMID:28935500 |
|
NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
|
|
G |
Lat |
linker for activation of T cells |
multiple interactions |
ISO |
Antigens results in increased phosphorylation of and results in increased activity of LAT protein; Quinoxalines analog inhibits the reaction [Antigens results in increased phosphorylation of and results in increased activity of LAT protein] |
CTD |
PMID:21958720 |
|
NCBI chr 1:180,936,536...180,941,561
Ensembl chr 1:180,936,534...180,941,578
|
|
G |
Lyn |
LYN proto-oncogene, Src family tyrosine kinase |
multiple interactions increases activity |
ISO |
Quinoxalines analog affects the reaction [Antigens results in increased activity of LYN protein] |
CTD |
PMID:21958720 |
|
NCBI chr 5:16,639,512...16,755,501
Ensembl chr 5:16,639,466...16,756,868
|
|
G |
Mapk1 |
mitogen activated protein kinase 1 |
multiple interactions increases phosphorylation |
ISO |
Quinoxalines analog inhibits the reaction [Antigens results in increased phosphorylation of MAPK1 protein] |
CTD |
PMID:21958720 |
|
NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
|
|
G |
Mapk3 |
mitogen activated protein kinase 3 |
increases phosphorylation multiple interactions |
ISO |
Antigens results in increased phosphorylation of MAPK3 protein Quinoxalines analog inhibits the reaction [Antigens results in increased phosphorylation of MAPK3 protein] |
CTD |
PMID:21958720 |
|
NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
|
|
G |
Mir10a |
microRNA 10a |
increases expression |
ISO |
Antigens results in increased expression of MIR10A mRNA |
CTD |
PMID:27038180 |
|
NCBI chr10:81,283,171...81,283,280
Ensembl chr10:81,283,171...81,283,280
|
|
G |
Mir125a |
microRNA 125a |
decreases expression |
ISO |
Antigens results in decreased expression of MIR125A mRNA |
CTD |
PMID:27038180 |
|
NCBI chr 1:58,677,626...58,677,710
Ensembl chr 1:58,677,626...58,677,710
|
|
G |
Mir126a |
microRNA 126a |
decreases expression |
ISO |
Antigens results in decreased expression of MIR126A mRNA |
CTD |
PMID:27038180 |
|
NCBI chr 3:9,415,063...9,415,180
Ensembl chr 3:9,415,063...9,415,180
|
|
G |
Mir142 |
microRNA 142 |
multiple interactions decreases expression |
ISO |
Dronabinol inhibits the reaction [Antigens results in decreased expression of MIR142 mRNA] |
CTD |
PMID:27038180 |
|
NCBI chr10:72,557,864...72,557,950
Ensembl chr10:72,557,857...72,557,967
|
|
G |
Mir145 |
microRNA 145 |
decreases expression |
ISO |
Antigens results in decreased expression of MIR145A mRNA |
CTD |
PMID:27038180 |
|
NCBI chr18:55,099,640...55,099,727
Ensembl chr18:55,099,640...55,099,727
|
|
G |
Mir151 |
microRNA 151 |
decreases expression |
ISO |
Antigens results in decreased expression of MIR151 mRNA |
CTD |
PMID:27038180 |
|
NCBI chr 7:105,172,377...105,172,473
|
|
G |
Mir187 |
microRNA 187 |
decreases expression |
ISO |
Antigens results in decreased expression of MIR187 mRNA |
CTD |
PMID:27038180 |
|
NCBI chr18:15,731,194...15,731,297
Ensembl chr18:15,731,194...15,731,297
|
|
G |
Mir21 |
microRNA 21 |
multiple interactions increases expression |
ISO |
[Dronabinol inhibits the reaction [Antigens results in increased expression of MIR21A mRNA]] which results in decreased expression of IFNG mRNA; Dronabinol inhibits the reaction [Antigens results in increased expression of MIR21A mRNA] |
CTD |
PMID:27038180 |
|
NCBI chr10:71,405,257...71,405,348
Ensembl chr10:71,405,257...71,405,348
|
|
G |
Mir210 |
microRNA 210 |
increases expression |
ISO |
Antigens results in increased expression of MIR210 mRNA |
CTD |
PMID:27038180 |
|
NCBI chr 1:196,326,343...196,326,452
Ensembl chr 1:196,326,337...196,326,454
|
|
G |
Mir221 |
microRNA 221 |
increases expression |
ISO |
Antigens results in increased expression of MIR221 mRNA |
CTD |
PMID:27038180 |
|
NCBI chr X:3,429,465...3,429,573
Ensembl chr X:3,429,465...3,429,573
|
|
G |
Mir223 |
microRNA 223 |
multiple interactions increases expression |
ISO |
Dronabinol inhibits the reaction [Antigens results in increased expression of MIR223 mRNA] |
CTD |
PMID:27038180 |
|
NCBI chr X:61,141,887...61,141,996
Ensembl chr X:61,141,887...61,141,996
|
|
G |
Mir29b1 |
microRNA 29b-1 |
multiple interactions decreases expression |
ISO |
[Dronabinol inhibits the reaction [Antigens results in decreased expression of MIR29B-1 mRNA]] which results in increased expression of SMAD7 mRNA; Dronabinol inhibits the reaction [Antigens results in decreased expression of MIR29B-1 mRNA] |
CTD |
PMID:27038180 |
|
NCBI chr 4:59,650,987...59,651,067
Ensembl chr 4:59,650,986...59,651,067
|
|
G |
Mir31 |
microRNA 31 |
increases expression |
ISO |
Antigens results in increased expression of MIR31 mRNA |
CTD |
PMID:27038180 |
|
NCBI chr 5:103,599,038...103,599,143
|
|
G |
Mir486 |
microRNA 486 |
increases expression |
ISO |
Antigens results in increased expression of MIR486 mRNA |
CTD |
PMID:27038180 |
|
|
|
G |
Ms4a2 |
membrane spanning 4-domains A2 |
multiple interactions decreases response to substance |
ISO |
MS4A2 protein mutant form inhibits the reaction [Antigens results in increased abundance of Hydrogen Peroxide]; MS4A2 protein mutant form inhibits the reaction [wortmannin inhibits the reaction [Antigens results in increased abundance of Hydrogen Peroxide]] MS4A2 protein mutant form results in decreased susceptibility to Antigens |
CTD |
PMID:19467708 |
|
NCBI chr 1:208,440,179...208,448,716
Ensembl chr 1:208,440,361...208,448,310
|
|
G |
Smad7 |
SMAD family member 7 |
multiple interactions |
ISO |
[Dronabinol inhibits the reaction [Antigens results in decreased expression of MIR29B-1 mRNA]] which results in increased expression of SMAD7 mRNA |
CTD |
PMID:27038180 |
|
NCBI chr18:68,988,429...69,016,774
Ensembl chr18:68,988,429...69,016,765
|
|
G |
Socs1 |
suppressor of cytokine signaling 1 |
multiple interactions increases expression |
ISO |
deoxynivalenol inhibits the reaction [Antigens results in increased expression of SOCS1 mRNA]; ochratoxin A inhibits the reaction [Antigens results in increased expression of SOCS1 mRNA] |
CTD |
PMID:28935500 |
|
NCBI chr10:4,882,651...4,884,342
Ensembl chr10:4,882,560...4,884,383
|
|
G |
Socs2 |
suppressor of cytokine signaling 2 |
multiple interactions increases expression |
ISO |
deoxynivalenol inhibits the reaction [Antigens results in increased expression of SOCS2 mRNA]; ochratoxin A inhibits the reaction [Antigens results in increased expression of SOCS2 mRNA] |
CTD |
PMID:28935500 |
|
NCBI chr 7:30,006,360...30,045,161
Ensembl chr 7:30,008,578...30,043,548
|
|
G |
Stat1 |
signal transducer and activator of transcription 1 |
multiple interactions |
ISO |
[deoxynivalenol results in increased susceptibility to Antigens] which results in increased expression of STAT1 mRNA; [ochratoxin A results in increased susceptibility to Antigens] which results in increased expression of STAT1 mRNA |
CTD |
PMID:28935500 |
|
NCBI chr 9:49,419,561...49,459,969
Ensembl chr 9:49,419,340...49,588,540
|
|
G |
Stat3 |
signal transducer and activator of transcription 3 |
multiple interactions |
ISO |
[ochratoxin A results in increased susceptibility to Antigens] which results in increased expression of STAT3 mRNA |
CTD |
PMID:28935500 |
|
NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057
|
|
G |
Stat4 |
signal transducer and activator of transcription 4 |
multiple interactions |
ISO |
[deoxynivalenol results in increased susceptibility to Antigens] which results in increased expression of STAT4 mRNA; [ochratoxin A results in increased susceptibility to Antigens] which results in increased expression of STAT4 mRNA |
CTD |
PMID:28935500 |
|
NCBI chr 9:49,472,660...49,588,540
Ensembl chr 9:49,419,340...49,588,540
|
|
G |
Syk |
spleen associated tyrosine kinase |
multiple interactions |
ISO |
Antigens results in increased phosphorylation of and results in increased activity of SYK protein; Quinoxalines analog inhibits the reaction [Antigens results in increased phosphorylation of and results in increased activity of SYK protein] |
CTD |
PMID:21958720 |
|
NCBI chr17:12,604,615...12,678,437
Ensembl chr17:12,604,619...12,661,410
|
|
G |
Tnf |
tumor necrosis factor |
increases secretion increases expression multiple interactions |
ISO |
Antigens results in increased secretion of TNF protein Antigens results in increased expression of TNF mRNA [deoxynivalenol results in increased susceptibility to Antigens] which results in increased expression of TNF protein; [ochratoxin A results in increased susceptibility to Antigens] which results in increased expression of TNF protein; Quinoxalines analog inhibits the reaction [Antigens results in increased expression of TNF mRNA]; Quinoxalines analog inhibits the reaction [Antigens results in increased secretion of TNF protein] |
CTD |
PMID:21958720 PMID:28935500 |
|
NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
|
|
|
G |
Cxcl10 |
C-X-C motif chemokine ligand 10 |
increases expression |
ISO |
KRN 7000 results in increased expression of CXCL10 protein |
CTD |
PMID:15867097 |
|
NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975
|
|
G |
Il12b |
interleukin 12B |
increases expression |
ISO |
KRN 7000 results in increased expression of IL12B protein |
CTD |
PMID:15867097 |
|
NCBI chr10:28,888,832...28,903,802
Ensembl chr10:28,893,008...28,902,903
|
|
|
G |
Abcb1a |
ATP binding cassette subfamily B member 1A |
multiple interactions increases chemical synthesis |
ISO |
Cyclosporine inhibits the reaction [ABCB1 protein results in increased chemical synthesis of globotriaosylceramide]; Ketoconazole inhibits the reaction [ABCB1 protein results in increased chemical synthesis of globotriaosylceramide] |
CTD |
PMID:14662772 |
|
NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
|
|
G |
Il1b |
interleukin 1 beta |
multiple interactions |
ISO |
Curcumin inhibits the reaction [IL1B protein promotes the reaction [Shiga Toxin binds to globotriaosylceramide]]; IL1B protein promotes the reaction [Shiga Toxin binds to globotriaosylceramide]; TNF protein promotes the reaction [IL1B protein promotes the reaction [Shiga Toxin binds to globotriaosylceramide]] |
CTD |
PMID:16819191 |
|
NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
|
|
G |
Tnf |
tumor necrosis factor |
multiple interactions |
ISO |
Curcumin inhibits the reaction [TNF protein promotes the reaction [Shiga Toxin binds to globotriaosylceramide]]; TNF protein promotes the reaction [IL1B protein promotes the reaction [Shiga Toxin binds to globotriaosylceramide]]; TNF protein promotes the reaction [Shiga Toxin binds to globotriaosylceramide] |
CTD |
PMID:16819191 |
|
NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
|
|
|
G |
Akr1c2 |
aldo-keto reductase family 1, member C2 |
increases expression |
ISO |
benzyl cinnamate results in increased expression of AKR1C2 mRNA |
CTD |
PMID:20491607 |
|
NCBI chr17:65,759,778...65,808,013
Ensembl chr17:65,759,788...65,775,764
|
|
G |
Cd86 |
CD86 molecule |
increases expression |
ISO |
benzyl cinnamate results in increased expression of CD86 protein |
CTD |
PMID:29540657 |
|
NCBI chr11:64,142,193...64,200,816
Ensembl chr11:64,163,828...64,200,818
|
|
G |
Cyp1a1 |
cytochrome P450, family 1, subfamily a, polypeptide 1 |
increases expression |
ISO |
benzyl cinnamate results in increased expression of CYP1A1 mRNA |
CTD |
PMID:20491607 |
|
NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
|
|
G |
Maff |
MAF bZIP transcription factor F |
increases expression |
ISO |
benzyl cinnamate results in increased expression of MAFF mRNA |
CTD |
PMID:20491607 |
|
NCBI chr 7:110,912,367...110,923,711
Ensembl chr 7:110,912,499...110,923,851
|
|
G |
Maoa |
monoamine oxidase A |
decreases activity |
ISO |
benzyl cinnamate results in decreased activity of MAOA protein |
CTD |
PMID:27270453 |
|
NCBI chr X:6,032,172...6,098,308
Ensembl chr X:6,030,795...6,099,593
|
|
G |
Maob |
monoamine oxidase B |
decreases activity |
ISO |
benzyl cinnamate results in decreased activity of MAOB protein |
CTD |
PMID:27270453 |
|
NCBI chr X:5,907,327...6,010,996
Ensembl chr X:5,907,266...6,011,003
|
|
G |
Mt1 |
metallothionein 1 |
increases expression |
ISO |
benzyl cinnamate results in increased expression of MT1A mRNA |
CTD |
PMID:20491607 |
|
NCBI chr19:10,826,032...10,827,048
Ensembl chr19:10,826,032...10,827,049 Ensembl chr17:10,826,032...10,827,049
|
|
G |
Mt2A |
metallothionein 2A |
increases expression |
ISO |
benzyl cinnamate results in increased expression of MT2A mRNA |
CTD |
PMID:20491607 |
|
NCBI chr19:10,832,009...10,832,783
Ensembl chr19:10,832,002...10,832,784
|
|
G |
Nqo1 |
NAD(P)H quinone dehydrogenase 1 |
increases expression |
ISO |
benzyl cinnamate results in increased expression of NQO1 mRNA |
CTD |
PMID:20491607 |
|
NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
|
|
G |
Txn1 |
thioredoxin 1 |
increases expression |
ISO |
benzyl cinnamate results in increased expression of TXN mRNA |
CTD |
PMID:20491607 |
|
NCBI chr 5:72,712,334...72,724,564
Ensembl chr 5:72,711,933...72,724,629
|
|
|
G |
Ins2 |
insulin 2 |
multiple interactions |
ISO |
[1-Methyl-3-isobutylxanthine co-treated with butylbenzyl phthalate co-treated with INS protein] results in increased abundance of monoethyl phosphate analog |
CTD |
PMID:26820058 |
|
NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775
|
|
|
G |
Abcb7 |
ATP binding cassette subfamily B member 7 |
affects binding |
ISO |
Fluorescein-5-isothiocyanate binds to ABCB7 protein |
CTD |
PMID:27129696 |
|
NCBI chr X:69,295,598...69,436,775
Ensembl chr X:69,295,552...69,436,858
|
|
G |
Akr1c2 |
aldo-keto reductase family 1, member C2 |
increases expression |
ISO |
Fluorescein-5-isothiocyanate results in increased expression of AKR1C2 mRNA |
CTD |
PMID:20491607 |
|
NCBI chr17:65,759,778...65,808,013
Ensembl chr17:65,759,788...65,775,764
|
|
G |
Anxa4 |
annexin A4 |
affects binding |
ISO |
Fluorescein-5-isothiocyanate binds to ANXA4 protein |
CTD |
PMID:27129696 |
|
NCBI chr 4:119,184,378...119,241,183
Ensembl chr 4:119,184,374...119,241,161
|
|
G |
Arhgap6 |
Rho GTPase activating protein 6 |
affects binding |
ISO |
Fluorescein-5-isothiocyanate binds to ARHGAP6 protein |
CTD |
PMID:27129696 |
|
NCBI chr X:24,953,464...25,490,003
Ensembl chr X:24,953,464...25,488,663
|
|
G |
Azi2 |
5-azacytidine induced 2 |
affects binding |
ISO |
Fluorescein-5-isothiocyanate binds to AZI2 protein |
CTD |
PMID:27129696 |
|
NCBI chr 8:117,773,248...117,797,844
Ensembl chr 8:117,773,279...117,797,847
|
|
G |
Capzb |
capping actin protein of muscle Z-line subunit beta |
affects binding |
ISO |
Fluorescein-5-isothiocyanate binds to CAPZB protein |
CTD |
PMID:27129696 |
|
NCBI chr 5:151,435,600...151,535,409
Ensembl chr 5:151,434,871...151,535,409
|
|
G |
Cd109 |
CD109 molecule |
affects binding |
ISO |
Fluorescein-5-isothiocyanate binds to CD109 protein |
CTD |
PMID:27129696 |
|
NCBI chr 8:79,454,480...79,569,195
Ensembl chr 8:79,454,480...79,569,194
|
|
G |
Cd180 |
CD180 molecule |
affects binding |
ISO |
Fluorescein-5-isothiocyanate binds to CD180 protein |
CTD |
PMID:27129696 |
|
NCBI chr 2:33,855,940...33,870,046
Ensembl chr 2:33,855,991...33,899,936
|
|
G |
Cd86 |
CD86 molecule |
increases expression |
ISO |
Fluorescein-5-isothiocyanate results in increased expression of CD86 protein |
CTD |
PMID:19665512 |
|
NCBI chr11:64,142,193...64,200,816
Ensembl chr11:64,163,828...64,200,818
|
|
G |
Cd93 |
CD93 molecule |
affects binding |
ISO |
Fluorescein-5-isothiocyanate binds to CD93 protein |
CTD |
PMID:27129696 |
|
NCBI chr 3:135,891,859...135,898,378
Ensembl chr 3:135,891,859...135,898,378
|
|
G |
Cdc20 |
cell division cycle 20 |
affects binding |
ISO |
Fluorescein-5-isothiocyanate binds to CDC20 protein |
CTD |
PMID:27129696 |
|
NCBI chr 5:131,966,203...131,970,406
Ensembl chr 5:131,966,215...131,970,512
|
|
G |
Copa |
COPI coat complex subunit alpha |
affects binding |
ISO |
Fluorescein-5-isothiocyanate binds to COPA protein |
CTD |
PMID:27129696 |
|
NCBI chr13:84,546,483...84,586,879
Ensembl chr13:84,545,943...84,586,874
|
|
G |
Cyp1a1 |
cytochrome P450, family 1, subfamily a, polypeptide 1 |
increases expression |
ISO |
Fluorescein-5-isothiocyanate results in increased expression of CYP1A1 mRNA |
CTD |
PMID:20491607 |
|
NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
|
|
G |
Dcaf4 |
DDB1 and CUL4 associated factor 4 |
affects binding |
ISO |
Fluorescein-5-isothiocyanate binds to DCAF4 protein |
CTD |
PMID:27129696 |
|
NCBI chr 6:103,154,847...103,180,992
Ensembl chr 6:103,154,867...103,180,982
|
|
G |
Dot1l |
DOT1 like histone lysine methyltransferase |
affects binding |
ISO |
Fluorescein-5-isothiocyanate binds to DOT1L protein |
CTD |
PMID:27129696 |
|
NCBI chr 7:8,918,764...8,959,474
Ensembl chr 7:8,917,786...8,956,475
|
|
G |
Elac1 |
elaC ribonuclease Z 1 |
affects binding |
ISO |
Fluorescein-5-isothiocyanate binds to ELAC1 protein |
CTD |
PMID:27129696 |
|
NCBI chr18:67,321,231...67,341,358
Ensembl chr18:67,323,583...67,340,936
|
|
G |
Enpp7 |
ectonucleotide pyrophosphatase/phosphodiesterase 7 |
affects binding |
ISO |
Fluorescein-5-isothiocyanate binds to ENPP7 protein |
CTD |
PMID:27129696 |
|
NCBI chr10:104,242,169...104,247,185
Ensembl chr10:104,242,223...104,246,589
|
|
G |
Flrt3 |
fibronectin leucine rich transmembrane protein 3 |
affects binding |
ISO |
Fluorescein-5-isothiocyanate binds to FLRT3 protein |
CTD |
PMID:27129696 |
|
NCBI chr 3:127,994,491...128,008,137
Ensembl chr 3:127,994,226...128,007,841
|
|
G |
Fn1 |
fibronectin 1 |
affects binding |
ISO |
Fluorescein-5-isothiocyanate binds to FN1 protein |
CTD |
PMID:27129696 |
|
NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678
|
|
G |
Hmox1 |
heme oxygenase 1 |
increases expression multiple interactions |
ISO |
Fluorescein-5-isothiocyanate results in increased expression of HMOX1 protein [Melatonin co-treated with diisodecyl phthalate co-treated with Fluorescein-5-isothiocyanate] results in increased expression of HMOX1 protein |
CTD |
PMID:27871981 |
|
NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
|
|
G |
Hspa5 |
heat shock protein family A (Hsp70) member 5 |
affects binding |
ISO |
Fluorescein-5-isothiocyanate binds to HSPA5 protein |
CTD |
PMID:27129696 |
|
NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891
|
|
G |
Hspa9 |
heat shock protein family A (Hsp70) member 9 |
affects binding |
ISO |
Fluorescein-5-isothiocyanate binds to HSPA9 protein |
CTD |
PMID:27129696 |
|
NCBI chr18:26,536,131...26,554,294
Ensembl chr18:26,535,798...26,554,292
|
|
G |
Ifng |
interferon gamma |
multiple interactions |
ISO |
[Dibutyl Phthalate co-treated with Fluorescein-5-isothiocyanate] results in increased secretion of IFNG protein; [Fluorescein-5-isothiocyanate co-treated with tributyrin] results in increased secretion of IFNG protein; [Fluorescein-5-isothiocyanate co-treated with tricaproin] results in increased secretion of IFNG protein; [tributyrin co-treated with Fluorescein-5-isothiocyanate] results in increased secretion of IFNG protein |
CTD |
PMID:29198882 PMID:36870414 |
|
NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
|
|
G |
Ikbkb |
inhibitor of nuclear factor kappa B kinase subunit beta |
affects binding |
ISO |
Fluorescein-5-isothiocyanate binds to IKBKB protein |
CTD |
PMID:27129696 |
|
NCBI chr16:69,319,487...69,373,251
Ensembl chr16:69,319,554...69,373,250
|
|
G |
Ikzf4 |
IKAROS family zinc finger 4 |
affects binding |
ISO |
Fluorescein-5-isothiocyanate binds to IKZF4 protein |
CTD |
PMID:27129696 |
|
NCBI chr 7:1,063,283...1,102,940
Ensembl chr 7:1,056,890...1,084,341
|
|
G |
Il17a |
interleukin 17A |
multiple interactions |
ISO |
[Fluorescein-5-isothiocyanate co-treated with tributyrin] results in increased secretion of IL17A protein |
CTD |
PMID:36870414 |
|
NCBI chr 9:23,144,402...23,147,889
Ensembl chr 9:23,144,402...23,147,889
|
|
G |
Il17re |
interleukin 17 receptor E |
affects binding |
ISO |
Fluorescein-5-isothiocyanate binds to IL17RE protein |
CTD |
PMID:27129696 |
|
NCBI chr 4:146,604,547...146,618,206
Ensembl chr 4:146,605,526...146,618,206
|
|
G |
Il31ra |
interleukin 31 receptor A |
affects binding |
ISO |
Fluorescein-5-isothiocyanate binds to IL31RA protein |
CTD |
PMID:27129696 |
|
NCBI chr 2:44,118,748...44,189,943
Ensembl chr 2:44,122,624...44,183,767
|
|
G |
Il4 |
interleukin 4 |
multiple interactions increases expression |
ISO |
[Dibutyl Phthalate co-treated with Fluorescein-5-isothiocyanate] results in increased secretion of IL4 protein; [dibutyrylglycerol analog co-treated with Fluorescein-5-isothiocyanate] affects the secretion of IL4 protein; [Fluorescein-5-isothiocyanate co-treated with tributyrin] results in increased secretion of IL4 protein; [Fluorescein-5-isothiocyanate co-treated with tricaproin] results in increased secretion of IL4 protein; [tributyrin co-treated with Fluorescein-5-isothiocyanate] results in increased secretion of IL4 protein; diisodecyl phthalate promotes the reaction [Fluorescein-5-isothiocyanate results in increased expression of IL4 protein]; Melatonin inhibits the reaction [diisodecyl phthalate promotes the reaction [Fluorescein-5-isothiocyanate results in increased expression of IL4 protein]] |
CTD |
PMID:27871981 PMID:29198882 PMID:36870414 |
|
NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
|
|
G |
Lypd3 |
Ly6/Plaur domain containing 3 |
affects binding |
ISO |
Fluorescein-5-isothiocyanate binds to LYPD3 protein |
CTD |
PMID:27129696 |
|
NCBI chr 1:80,226,449...80,230,901
Ensembl chr 1:80,226,449...80,230,901
|
|
G |
Maff |
MAF bZIP transcription factor F |
increases expression |
ISO |
Fluorescein-5-isothiocyanate results in increased expression of MAFF mRNA |
CTD |
PMID:20491607 |
|
NCBI chr 7:110,912,367...110,923,711
Ensembl chr 7:110,912,499...110,923,851
|
|
G |
Map3k20 |
mitogen-activated protein kinase kinase kinase 20 |
affects binding |
ISO |
Fluorescein-5-isothiocyanate binds to MAP3K20 protein |
CTD |
PMID:27129696 |
|
NCBI chr 3:57,130,539...57,289,943
Ensembl chr 3:57,130,551...57,289,626
|
|
G |
Mapk1 |
mitogen activated protein kinase 1 |
increases phosphorylation multiple interactions |
ISO |
Fluorescein-5-isothiocyanate results in increased phosphorylation of MAPK1 protein Fluorescein-5-isothiocyanate inhibits the reaction [Dinitrofluorobenzene results in increased phosphorylation of MAPK1 protein]; Fluorescein-5-isothiocyanate inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein] |
CTD |
PMID:27129696 |
|
NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
|
|
G |
Mapk3 |
mitogen activated protein kinase 3 |
increases phosphorylation multiple interactions |
ISO |
Fluorescein-5-isothiocyanate results in increased phosphorylation of MAPK3 protein Fluorescein-5-isothiocyanate inhibits the reaction [Dinitrofluorobenzene results in increased phosphorylation of MAPK3 protein]; Fluorescein-5-isothiocyanate inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK3 protein] |
CTD |
PMID:27129696 |
|
NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
|
|
G |
Mapk8 |
mitogen-activated protein kinase 8 |
multiple interactions increases phosphorylation |
ISO |
Fluorescein-5-isothiocyanate inhibits the reaction [Dinitrofluorobenzene results in increased phosphorylation of MAPK8 protein]; Fluorescein-5-isothiocyanate inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein] Fluorescein-5-isothiocyanate results in increased phosphorylation of MAPK8 protein |
CTD |
PMID:27129696 |
|
NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981
|
|
G |
Mapk9 |
mitogen-activated protein kinase 9 |
multiple interactions increases phosphorylation |
ISO |
Fluorescein-5-isothiocyanate inhibits the reaction [Dinitrofluorobenzene results in increased phosphorylation of MAPK9 protein]; Fluorescein-5-isothiocyanate inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK9 protein] Fluorescein-5-isothiocyanate results in increased phosphorylation of MAPK9 protein |
CTD |
PMID:27129696 |
|
NCBI chr10:34,169,661...34,211,138
Ensembl chr10:34,169,675...34,210,178
|
|
G |
Mt2A |
metallothionein 2A |
increases expression |
ISO |
Fluorescein-5-isothiocyanate results in increased expression of MT2A mRNA |
CTD |
PMID:20491607 |
|
NCBI chr19:10,832,009...10,832,783
Ensembl chr19:10,832,002...10,832,784
|
|
G |
Mybpc1 |
myosin binding protein C1 |
affects binding |
ISO |
Fluorescein-5-isothiocyanate binds to MYBPC1 protein |
CTD |
PMID:27129696 |
|
NCBI chr 7:22,930,350...23,015,981
Ensembl chr 7:22,930,350...23,015,957
|
|
G |
Nfe2l2 |
NFE2 like bZIP transcription factor 2 |
multiple interactions |
ISO |
[Melatonin co-treated with diisodecyl phthalate co-treated with Fluorescein-5-isothiocyanate] results in increased expression of NFE2L2 protein |
CTD |
PMID:27871981 |
|
NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737
|
|
G |
Nqo1 |
NAD(P)H quinone dehydrogenase 1 |
increases expression multiple interactions |
ISO |
Fluorescein-5-isothiocyanate results in increased expression of NQO1 mRNA Fluorescein-5-isothiocyanate results in increased expression of NQO1 protein diisodecyl phthalate inhibits the reaction [Fluorescein-5-isothiocyanate results in increased expression of NQO1 protein]; Melatonin inhibits the reaction [diisodecyl phthalate inhibits the reaction [Fluorescein-5-isothiocyanate results in increased expression of NQO1 protein]] |
CTD |
PMID:20491607 PMID:27871981 |
|
NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
|
|
G |
Plce1 |
phospholipase C, epsilon 1 |
affects binding |
ISO |
Fluorescein-5-isothiocyanate binds to PLCE1 protein |
CTD |
PMID:27129696 |
|
NCBI chr 1:236,243,445...236,552,571
Ensembl chr 1:236,244,683...236,551,438
|
|
G |
Postn |
periostin |
affects binding |
ISO |
Fluorescein-5-isothiocyanate binds to POSTN protein |
CTD |
PMID:27129696 |
|
NCBI chr 2:138,527,714...138,559,098
Ensembl chr 2:138,527,696...138,559,099
|
|
G |
Pprc1 |
PPARG related coactivator 1 |
affects binding |
ISO |
Fluorescein-5-isothiocyanate binds to PPRC1 protein |
CTD |
PMID:27129696 |
|
NCBI chr 1:244,901,985...244,918,587
Ensembl chr 1:244,902,179...244,918,587
|
|
G |
Prkcb |
protein kinase C, beta |
increases expression |
ISO |
Fluorescein-5-isothiocyanate results in increased expression of PRKCB protein |
CTD |
PMID:31958493 |
|
NCBI chr 1:176,832,173...177,163,539
Ensembl chr 1:176,832,226...177,163,536
|
|
G |
Psd4 |
pleckstrin and Sec7 domain containing 4 |
affects binding |
ISO |
Fluorescein-5-isothiocyanate binds to PSD4 protein |
CTD |
PMID:27129696 |
|
NCBI chr 3:7,137,069...7,173,571
Ensembl chr 3:7,137,155...7,173,571
|
|
G |
Psmd14 |
proteasome 26S subunit, non-ATPase 14 |
affects binding |
ISO |
Fluorescein-5-isothiocyanate binds to PSMD14 protein |
CTD |
PMID:27129696 |
|
NCBI chr 3:46,254,338...46,347,076
Ensembl chr 3:46,254,330...46,347,076
|
|
G |
Rela |
RELA proto-oncogene, NF-kB subunit |
multiple interactions |
ISO |
[diisodecyl phthalate co-treated with Fluorescein-5-isothiocyanate] results in increased phosphorylation of RELA protein; Melatonin inhibits the reaction [[diisodecyl phthalate co-treated with Fluorescein-5-isothiocyanate] results in increased phosphorylation of RELA protein] |
CTD |
PMID:27871981 |
|
NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
|
|
G |
Scn5a |
sodium voltage-gated channel alpha subunit 5 |
affects binding |
ISO |
Fluorescein-5-isothiocyanate binds to SCN5A protein |
CTD |
PMID:27129696 |
|
NCBI chr 8:119,220,905...119,318,816
Ensembl chr 8:119,220,905...119,318,769
|
|
G |
Skor1 |
SKI family transcriptional corepressor 1 |
affects binding |
ISO |
Fluorescein-5-isothiocyanate binds to SKOR1 protein |
CTD |
PMID:27129696 |
|
NCBI chr 8:63,599,153...63,609,727
Ensembl chr 8:63,599,165...63,607,756
|
|
G |
Slc10a1 |
solute carrier family 10 member 1 |
multiple interactions increases uptake |
ISO |
Taurocholic Acid promotes the reaction [SLC10A1 protein results in increased uptake of Fluorescein-5-isothiocyanate] |
CTD |
PMID:32209977 |
|
NCBI chr 6:100,613,045...100,626,670
Ensembl chr 6:100,613,045...100,626,670
|
|
G |
Slc38a10 |
solute carrier family 38, member 10 |
affects binding |
ISO |
Fluorescein-5-isothiocyanate binds to SLC38A10 protein |
CTD |
PMID:27129696 |
|
NCBI chr10:105,386,836...105,436,636
Ensembl chr10:105,386,836...105,436,636
|
|
G |
Stat3 |
signal transducer and activator of transcription 3 |
multiple interactions increases phosphorylation |
ISO |
diisodecyl phthalate promotes the reaction [Fluorescein-5-isothiocyanate results in increased phosphorylation of STAT3 protein]; Melatonin inhibits the reaction [diisodecyl phthalate promotes the reaction [Fluorescein-5-isothiocyanate results in increased phosphorylation of STAT3 protein]] |
CTD |
PMID:27871981 |
|
NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057
|
|
G |
Stat5a |
signal transducer and activator of transcription 5A |
multiple interactions increases phosphorylation |
ISO |
diisodecyl phthalate promotes the reaction [Fluorescein-5-isothiocyanate results in increased phosphorylation of STAT5 protein]; Melatonin inhibits the reaction [diisodecyl phthalate promotes the reaction [Fluorescein-5-isothiocyanate results in increased phosphorylation of STAT5 protein]] |
CTD |
PMID:27871981 |
|
NCBI chr10:85,785,537...85,809,869
Ensembl chr10:85,785,537...85,809,866
|
|
G |
Stat6 |
signal transducer and activator of transcription 6 |
increases phosphorylation multiple interactions |
ISO |
Fluorescein-5-isothiocyanate results in increased phosphorylation of STAT6 protein diisodecyl phthalate promotes the reaction [Fluorescein-5-isothiocyanate results in increased phosphorylation of STAT6 protein]; Melatonin inhibits the reaction [diisodecyl phthalate promotes the reaction [Fluorescein-5-isothiocyanate results in increased phosphorylation of STAT6 protein]] |
CTD |
PMID:27871981 |
|
NCBI chr 7:63,480,229...63,497,551
Ensembl chr 7:63,479,642...63,498,495
|
|
G |
Trpa1 |
transient receptor potential cation channel, subfamily A, member 1 |
affects binding |
ISO |
Fluorescein-5-isothiocyanate binds to TRPA1 protein |
CTD |
PMID:27129696 |
|
NCBI chr 5:4,379,862...4,434,133
Ensembl chr 5:4,379,999...4,433,570
|
|
G |
Tslp |
thymic stromal lymphopoietin |
increases expression multiple interactions |
ISO |
Fluorescein-5-isothiocyanate results in increased expression of TSLP protein diisodecyl phthalate promotes the reaction [Fluorescein-5-isothiocyanate results in increased expression of TSLP protein]; Melatonin inhibits the reaction [diisodecyl phthalate promotes the reaction [Fluorescein-5-isothiocyanate results in increased expression of TSLP protein]] |
CTD |
PMID:27871981 |
|
NCBI chr18:24,447,409...24,454,244
Ensembl chr18:24,449,844...24,453,548
|
|
G |
Txn1 |
thioredoxin 1 |
increases expression |
ISO |
Fluorescein-5-isothiocyanate results in increased expression of TXN mRNA |
CTD |
PMID:20491607 |
|
NCBI chr 5:72,712,334...72,724,564
Ensembl chr 5:72,711,933...72,724,629
|
|
G |
Usp3 |
ubiquitin specific peptidase 3 |
affects binding |
ISO |
Fluorescein-5-isothiocyanate binds to USP3 protein |
CTD |
PMID:27129696 |
|
NCBI chr 8:67,078,249...67,154,109
Ensembl chr 8:67,079,927...67,154,111
|
|
|
G |
Cd14 |
CD14 molecule |
multiple interactions |
EXP |
CD14 protein affects the reaction [G(M1) Ganglioside results in increased secretion of Nitric Oxide] |
CTD |
PMID:16651628 |
|
NCBI chr18:28,335,522...28,337,383
Ensembl chr18:28,335,340...28,337,261
|
|
G |
Cdkn1a |
cyclin-dependent kinase inhibitor 1A |
increases expression |
EXP |
G(M1) Ganglioside results in increased expression of CDKN1A protein |
CTD |
PMID:15654767 |
|
NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
|
|
G |
Cdkn1b |
cyclin-dependent kinase inhibitor 1B |
decreases expression |
EXP |
G(M1) Ganglioside results in decreased expression of CDKN1B protein |
CTD |
PMID:15654767 |
|
NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982
|
|
G |
Npc1 |
NPC intracellular cholesterol transporter 1 |
affects localization |
ISO |
NPC1 affects the localization of G(M1) Ganglioside |
CTD |
PMID:12183525 |
|
NCBI chr18:3,379,482...3,425,100
Ensembl chr18:3,379,482...3,425,049
|
|
G |
Ntrk1 |
neurotrophic receptor tyrosine kinase 1 |
multiple interactions |
EXP |
G(M1) Ganglioside inhibits the reaction [Methylmercury Compounds results in decreased phosphorylation of NTRK1 protein]; G(M1) Ganglioside inhibits the reaction [staurosporine aglycone results in decreased phosphorylation of NTRK1 protein] |
CTD |
PMID:25545984 |
|
NCBI chr 2:173,236,961...173,253,806
Ensembl chr 2:173,236,963...173,253,770
|
|
G |
Pld1 |
phospholipase D1 |
multiple interactions |
EXP |
PLD1 protein affects the reaction [dinitrophenyl-bovine serum albumin affects the localization of G(M1) Ganglioside] |
CTD |
PMID:19794068 |
|
NCBI chr 2:110,849,205...111,047,304
Ensembl chr 2:110,893,608...111,047,692
|
|
G |
Pld2 |
phospholipase D2 |
multiple interactions |
EXP |
PLD2 protein affects the reaction [dinitrophenyl-bovine serum albumin affects the localization of G(M1) Ganglioside] |
CTD |
PMID:19794068 |
|
NCBI chr10:55,256,326...55,274,192
Ensembl chr10:55,256,359...55,272,808
|
|
G |
Slc18a2 |
solute carrier family 18 member A2 |
increases expression |
EXP |
G(M1) Ganglioside results in increased expression of SLC18A2 mRNA |
CTD |
PMID:14552908 |
|
NCBI chr 1:258,413,748...258,449,143
Ensembl chr 1:258,413,959...258,448,325
|
|
G |
Slc6a3 |
solute carrier family 6 member 3 |
increases expression |
EXP |
G(M1) Ganglioside results in increased expression of SLC6A3 mRNA |
CTD |
PMID:14552908 |
|
NCBI chr 1:29,709,443...29,750,413
Ensembl chr 1:29,709,443...29,750,413
|
|
G |
Th |
tyrosine hydroxylase |
increases activity |
EXP |
G(M1) Ganglioside results in increased activity of TH protein |
CTD |
PMID:14552908 |
|
NCBI chr 1:198,071,500...198,078,832
Ensembl chr 1:198,071,503...198,109,767
|
|
G |
Tlr4 |
toll-like receptor 4 |
decreases expression |
EXP |
G(M1) Ganglioside results in decreased expression of TLR4 protein |
CTD |
PMID:16651628 |
|
NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628
|
|
|
G |
Cd80 |
Cd80 molecule |
increases expression |
ISO |
glucuronoxylomannan results in increased expression of CD80 protein |
CTD |
PMID:12864811 |
|
NCBI chr11:62,254,543...62,293,414
Ensembl chr11:62,254,624...62,292,030
|
|
G |
Cd86 |
CD86 molecule |
increases expression |
ISO |
glucuronoxylomannan results in increased expression of CD86 protein |
CTD |
PMID:12864811 |
|
NCBI chr11:64,142,193...64,200,816
Ensembl chr11:64,163,828...64,200,818
|
|
G |
Ctla4 |
cytotoxic T-lymphocyte-associated protein 4 |
increases expression |
ISO |
glucuronoxylomannan results in increased expression of CTLA4 protein |
CTD |
PMID:12864811 |
|
NCBI chr 9:62,318,874...62,325,978
Ensembl chr 9:62,319,312...62,324,963
|
|
G |
Il10 |
interleukin 10 |
increases secretion |
ISO |
glucuronoxylomannan results in increased secretion of IL10 protein |
CTD |
PMID:12864811 |
|
NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
|
|
G |
Il12a |
interleukin 12A |
multiple interactions |
ISO |
glucuronoxylomannan results in decreased secretion of [IL12A protein binds to IL12B protein] |
CTD |
PMID:12864811 |
|
NCBI chr 2:152,965,769...152,973,035
Ensembl chr 2:152,965,769...152,972,734
|
|
G |
Il12b |
interleukin 12B |
multiple interactions |
ISO |
glucuronoxylomannan results in decreased secretion of [IL12A protein binds to IL12B protein] |
CTD |
PMID:12864811 |
|
NCBI chr10:28,888,832...28,903,802
Ensembl chr10:28,893,008...28,902,903
|
|
G |
Il12rb2 |
interleukin 12 receptor subunit beta 2 |
decreases expression |
ISO |
glucuronoxylomannan results in decreased expression of IL12RB2 protein |
CTD |
PMID:12047756 PMID:12864811 |
|
NCBI chr 4:96,426,396...96,515,251
Ensembl chr 4:96,426,842...96,515,289
|
|
|
G |
Ccr5 |
C-C motif chemokine receptor 5 |
decreases expression |
ISO |
isopentenyl pyrophosphate results in decreased expression of CCR5 protein |
CTD |
PMID:11994442 |
|
NCBI chr 8:123,752,423...123,757,538
Ensembl chr 8:123,752,325...123,759,260
|
|
G |
Fdps |
farnesyl diphosphate synthase |
multiple interactions |
ISO |
[zoledronic acid results in decreased activity of FDPS protein] which results in increased abundance of isopentenyl pyrophosphate |
CTD |
PMID:19699819 |
|
NCBI chr 2:174,497,402...174,507,031
Ensembl chr 2:174,486,665...174,507,776
|
|
G |
Fgf9 |
fibroblast growth factor 9 |
increases expression |
ISO |
isopentenyl pyrophosphate results in increased expression of FGF9 mRNA; isopentenyl pyrophosphate results in increased expression of FGF9 protein |
CTD |
PMID:14704367 |
|
NCBI chr15:32,208,993...32,254,952
Ensembl chr15:32,210,074...32,253,309
|
|
G |
Ifng |
interferon gamma |
multiple interactions increases expression |
ISO |
Calcitriol inhibits the reaction [isopentenyl pyrophosphate results in increased expression of IFNG protein] |
CTD |
PMID:15879110 |
|
NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
|
|
G |
Il2ra |
interleukin 2 receptor subunit alpha |
multiple interactions increases expression |
ISO |
Calcitriol inhibits the reaction [isopentenyl pyrophosphate results in increased expression of IL2RA protein] |
CTD |
PMID:15879110 |
|
NCBI chr17:66,849,974...66,898,665
Ensembl chr17:66,849,974...66,898,697
|
|
G |
Mvk |
mevalonate kinase |
multiple interactions decreases activity |
ISO |
isopentenyl pyrophosphate inhibits the reaction [MVK protein results in increased hydrolysis of Adenosine Triphosphate]; isopentenyl pyrophosphate inhibits the reaction [MVK protein results in increased phosphorylation of Mevalonic Acid] isopentenyl pyrophosphate results in decreased activity of MVK protein |
CTD |
PMID:9392419 |
|
NCBI chr12:42,141,391...42,158,893
Ensembl chr12:42,141,384...42,158,882
|
|
G |
Trpa1 |
transient receptor potential cation channel, subfamily A, member 1 |
multiple interactions |
ISO |
isopentenyl pyrophosphate inhibits the reaction [cinnamaldehyde results in increased activity of TRPA1 protein] |
CTD |
PMID:21353389 |
|
NCBI chr 5:4,379,862...4,434,133
Ensembl chr 5:4,379,999...4,433,570
|
|
G |
Trpv3 |
transient receptor potential cation channel, subfamily V, member 3 |
multiple interactions |
ISO |
isopentenyl pyrophosphate inhibits the reaction [Camphor results in increased activity of TRPV3 protein] |
CTD |
PMID:21353389 |
|
NCBI chr10:57,883,546...57,915,865
Ensembl chr10:57,883,546...57,913,296
|
|
G |
Vdr |
vitamin D receptor |
multiple interactions increases expression |
ISO |
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [isopentenyl pyrophosphate results in increased expression of VDR protein]; Go 6976 inhibits the reaction [isopentenyl pyrophosphate results in increased expression of VDR protein]; U 0126 inhibits the reaction [isopentenyl pyrophosphate results in increased expression of VDR protein] |
CTD |
PMID:15879110 |
|
NCBI chr 7:128,987,981...129,037,677
Ensembl chr 7:128,987,981...129,037,677
|
|
|
G |
Csf2 |
colony stimulating factor 2 |
multiple interactions |
ISO |
CSF2 protein promotes the reaction [lipoarabinomannan results in increased secretion of CXCL8 protein] |
CTD |
PMID:12176910 |
|
NCBI chr10:38,386,945...38,388,926
Ensembl chr10:38,386,945...38,389,199
|
|
G |
Cxcr2 |
C-X-C motif chemokine receptor 2 |
decreases expression |
ISO |
lipoarabinomannan results in decreased expression of CXCR2 protein |
CTD |
PMID:10950785 |
|
NCBI chr 9:75,729,493...75,735,868
Ensembl chr 9:75,729,115...75,739,425
|
|
G |
Il12b |
interleukin 12B |
multiple interactions |
ISO |
lipoarabinomannan inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B protein] |
CTD |
PMID:16263713 |
|
NCBI chr10:28,888,832...28,903,802
Ensembl chr10:28,893,008...28,902,903
|
|
G |
Irak1 |
interleukin-1 receptor-associated kinase 1 |
multiple interactions |
ISO |
lipoarabinomannan inhibits the reaction [IRAK1 protein binds to TRAF6 protein] |
CTD |
PMID:16263713 |
|
NCBI chr X:151,768,621...151,778,521
Ensembl chr X:151,768,777...151,778,521
|
|
G |
Irak3 |
interleukin-1 receptor-associated kinase 3 |
increases expression increases expression |
ISO |
lipoarabinomannan results in increased expression of IRAK3 protein Lipoarabinomannan increases expression of Irak3 mRNA and protein in macrophages |
CTD RGD |
PMID:16263713 PMID:16263713 |
RGD:36049804 |
NCBI chr 7:55,653,949...55,714,371
Ensembl chr 7:55,653,962...55,713,121
|
|
G |
Mmp9 |
matrix metallopeptidase 9 |
increases activity |
ISO |
lipoarabinomannan results in increased activity of MMP9 protein |
CTD |
PMID:11839551 |
|
NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
|
|
G |
Nfkb1 |
nuclear factor kappa B subunit 1 |
multiple interactions |
ISO |
lipoarabinomannan results in decreased localization of and results in decreased activity of NFKB1 protein |
CTD |
PMID:16263713 |
|
NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404
|
|
G |
Nfkbia |
NFKB inhibitor alpha |
decreases phosphorylation |
ISO |
lipoarabinomannan results in decreased phosphorylation of NFKBIA protein |
CTD |
PMID:16263713 |
|
NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
|
|
G |
Rel |
REL proto-oncogene, NF-kB subunit |
multiple interactions |
ISO |
lipoarabinomannan results in decreased localization of and results in decreased activity of REL protein |
CTD |
PMID:16263713 |
|
NCBI chr14:97,690,105...97,721,194
Ensembl chr14:97,695,161...97,720,892
|
|
G |
Traf6 |
TNF receptor associated factor 6 |
multiple interactions |
ISO |
lipoarabinomannan inhibits the reaction [IRAK1 protein binds to TRAF6 protein] |
CTD |
PMID:16263713 |
|
NCBI chr 3:87,963,517...87,988,316
Ensembl chr 3:87,963,514...87,983,507
|
|
|
G |
Ins2 |
insulin 2 |
multiple interactions |
ISO |
[1-Methyl-3-isobutylxanthine co-treated with butylbenzyl phthalate co-treated with INS protein] results in increased abundance of methylphosphate analog |
CTD |
PMID:26820058 |
|
NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775
|
|
|
G |
Il12rb1 |
interleukin 12 receptor subunit beta 1 |
increases expression |
ISO |
3,3-dimethylallyl pyrophosphate results in increased expression of IL12RB1 protein |
CTD |
PMID:12932289 |
|
NCBI chr16:18,620,228...18,633,207
Ensembl chr16:18,620,770...18,632,769
|
|
G |
Mvk |
mevalonate kinase |
decreases activity multiple interactions |
ISO |
3,3-dimethylallyl pyrophosphate results in decreased activity of MVK protein 3,3-dimethylallyl pyrophosphate inhibits the reaction [MVK protein results in increased hydrolysis of Adenosine Triphosphate]; 3,3-dimethylallyl pyrophosphate inhibits the reaction [MVK protein results in increased phosphorylation of Mevalonic Acid] |
CTD |
PMID:9392419 |
|
NCBI chr12:42,141,391...42,158,893
Ensembl chr12:42,141,384...42,158,882
|
|
G |
Tnfrsf1b |
TNF receptor superfamily member 1B |
increases expression |
ISO |
3,3-dimethylallyl pyrophosphate results in increased expression of TNFRSF1B protein |
CTD |
PMID:12932289 |
|
NCBI chr 5:157,070,642...157,104,216
Ensembl chr 5:157,070,642...157,104,206
|
|