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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:(E)-4-hydroxynon-2-enal
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Accession:CHEBI:58968 term browser browse the term
Definition:The E (trans) stereoisomer of 4-hydroxynon-2-enal; it is the primary alpha,beta-unsaturated hydroxyalkenal produced by lipid peroxidation in cells.
Synonyms:exact_synonym: (2E)-4-hydroxynon-2-enal
 related_synonym: (E)-4-hydroxy-2-nonenal;   4-Hydroxy-2,3-trans-nonenal;   4-hydroxynonenal;   Formula=C9H16O2;   HNE;   InChI=1S/C9H16O2/c1-2-3-4-6-9(11)7-5-8-10/h5,7-9,11H,2-4,6H2,1H3/b7-5+;   InChIKey=JVJFIQYAHPMBBX-FNORWQNLSA-N;   SMILES=[H]C(=O)\\C=C\\C(O)CCCCC;   trans-4-Hydroxy-2-nonenal
 xref: CAS:18286-49-2;   LIPID_MAPS_instance:LMFA06000051;   PMID:16603628;   PMID:17189262;   PMID:23543734;   PMID:26800898


show annotations for term's descendants           Sort by:
(E)-4-hydroxynon-2-enal term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gsta4 glutathione S-transferase alpha 4 affects binding EXP (E)-4-hydroxynon-2-enal binds to Gsta4 protein RGD PMID:11018474 RGD:1641942 NCBI chr 8:79,066,967...79,084,193
Ensembl chr 8:79,066,934...79,084,182 		JBrowse link
G Gstp1 glutathione S-transferase pi 1 affects binding EXP (E)-4-hydroxynon-2-enal binds to Gstp1 protein RGD PMID:11018474 RGD:1641942 NCBI chr 1:210,767,237...210,770,242
Ensembl chr 1:201,321,672...201,340,226 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20845
    role 20805
      application 20606
        solvent 17439
          formic acid 9443
            formyl group 9404
              aldehyde 9404
                hydroxyaldehyde 807
                  4-hydroxynonenal 805
                    (E)-4-hydroxynon-2-enal 2
                      (2E,4R)-4-hydroxynon-2-enal 0
                      (2E,4S)-4-hydroxynon-2-enal 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 20845
    subatomic particle 20843
      composite particle 20843
        hadron 20843
          baryon 20843
            nucleon 20843
              atomic nucleus 20843
                atom 20843
                  main group element atom 20766
                    p-block element atom 20766
                      carbon group element atom 20699
                        carbon atom 20693
                          organic molecular entity 20693
                            heteroorganic entity 20202
                              organochalcogen compound 19890
                                organooxygen compound 19792
                                  carbon oxoacid 19137
                                    carboxylic acid 19134
                                      carboacyl group 18064
                                        univalent carboacyl group 18064
                                          formyl group 9404
                                            aldehyde 9404
                                              aliphatic aldehyde 2439
                                                fatty aldehyde 2165
                                                  unsaturated fatty aldehyde 817
                                                    monounsaturated fatty aldehyde 812
                                                      4-hydroxynonenal 805
                                                        4-hydroxynon-2-enal 805
                                                          (E)-4-hydroxynon-2-enal 2
                                                            (2E,4R)-4-hydroxynon-2-enal 0
                                                            (2E,4S)-4-hydroxynon-2-enal 0
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