The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
A dialdehyde that is propane substituted by two oxo groups at the terminal carbon atoms respectively. A biomarker of oxidative damage to lipids caused by smoking, it exists in vivo mainly in the enol form.
AGT protein results in increased abundance of Malondialdehyde AGT protein modified form results in increased abundance of Malondialdehyde FNDC5 protein inhibits the reaction [AGT protein modified form results in increased abundance of Malondialdehyde] Malondialdehyde binds to AGT protein modified form Atorvastatin inhibits the reaction [AGT protein results in increased abundance of Malondialdehyde]; isorhapontigenin inhibits the reaction [AGT protein results in increased abundance of Malondialdehyde]
[AKT1 gene mutant form co-treated with MET gene mutant form] results in increased abundance of Malondialdehyde; Orlistat inhibits the reaction [[AKT1 gene mutant form co-treated with MET gene mutant form] results in increased abundance of Malondialdehyde]
ALB protein affects the reaction [[Iron co-treated with Bicarbonates] results in increased abundance of Malondialdehyde]; ALB protein inhibits the reaction [[Iron co-treated with Phosphates] results in increased abundance of Malondialdehyde]
APC protein affects the abundance of Malondialdehyde bis(2-guanidinoethyl)disulfide inhibits the reaction [APC protein affects the abundance of Malondialdehyde]; FeCl tetrakis-2-(triethyleneglycolmonomethylether)pyridylporphyrin inhibits the reaction [APC protein affects the abundance of Malondialdehyde]; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [APC protein affects the abundance of Malondialdehyde]
[[BGN mRNA alternative form binds to OTUB1 protein] which binds to and results in decreased ubiquitination of and results in increased stability of SLC7A11 protein] which results in decreased abundance of Malondialdehyde
CAT protein modified form results in decreased abundance of Malondialdehyde [SOD1 protein modified form co-treated with CAT protein modified form] results in decreased abundance of Malondialdehyde
Malondialdehyde results in increased expression of COL1A2 mRNA MAPK8 protein promotes the reaction [Malondialdehyde results in increased expression of COL1A2 mRNA]
FNDC5 protein inhibits the reaction [AGT protein modified form results in increased abundance of Malondialdehyde] FNDC5 protein results in decreased abundance of Malondialdehyde NFE2L2 protein promotes the reaction [FNDC5 protein results in decreased abundance of Malondialdehyde]
[cobaltiprotoporphyrin results in increased expression of HMOX1 protein] inhibits the reaction [Ethanol results in increased abundance of Malondialdehyde]; zinc protoporphyrin inhibits the reaction [[cobaltiprotoporphyrin results in increased expression of HMOX1 protein] inhibits the reaction [Ethanol results in increased abundance of Malondialdehyde]]
Amino Acids inhibits the reaction [KL gene mutant form results in increased abundance of Malondialdehyde]; H 1356 inhibits the reaction [Amino Acids inhibits the reaction [KL gene mutant form results in increased abundance of Malondialdehyde]]
[AKT1 gene mutant form co-treated with MET gene mutant form] results in increased abundance of Malondialdehyde; Orlistat inhibits the reaction [[AKT1 gene mutant form co-treated with MET gene mutant form] results in increased abundance of Malondialdehyde]
NFE2L2 protein inhibits the reaction [Tobacco Smoke Pollution results in increased abundance of Malondialdehyde] NFE2L2 protein promotes the reaction [FNDC5 protein results in decreased abundance of Malondialdehyde]
[[BGN mRNA alternative form binds to OTUB1 protein] which binds to and results in decreased ubiquitination of and results in increased stability of SLC7A11 protein] which results in decreased abundance of Malondialdehyde
[PRKD2 protein affects the susceptibility to [erastin co-treated with bafilomycin A1]] which affects the abundance of Malondialdehyde; [PRKD2 protein affects the susceptibility to erastin] which affects the abundance of Malondialdehyde
[[BGN mRNA alternative form binds to OTUB1 protein] which binds to and results in decreased ubiquitination of and results in increased stability of SLC7A11 protein] which results in decreased abundance of Malondialdehyde
[SOD1 protein modified form co-treated with CAT protein modified form] results in decreased abundance of Malondialdehyde SOD1 protein modified form results in decreased abundance of Malondialdehyde
XRCC1 protein results in decreased abundance of Malondialdehyde Acetylcysteine inhibits the reaction [XRCC1 gene mutant form results in increased abundance of Malondialdehyde]; Acetylcysteine promotes the reaction [XRCC1 protein results in decreased abundance of Malondialdehyde]