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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:sodium aurothiomalate
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Accession:CHEBI:5516 term browser browse the term
Definition:A variable mixture of the mono- and di-sodium salts of aurothiomalic acid. It is used for treatment of rheumatoid arthritis.
Synonyms:related_synonym: Gold sodium thiomalate;   Myochrysine (TN)
 alt_id: CHEBI:75985
 xref: CAS:12244-57-4;   KEGG:D00992
 xref_mesh: MESH:D006052
 xref: PMID:19192274;   PMID:19194667;   PMID:20099230;   PMID:20225983;   PMID:20386869;   PMID:21467262;   PMID:23686086;   PMID:2571649;   PMID:2822844;   PMID:2840130;   PMID:2977403;   PMID:3134898;   PMID:3936929;   PMID:445303;   PMID:6318557;   PMID:6427463;   PMID:6812186;   PMID:7525650;   PMID:7720377;   PMID:818413;   PMID:8445531;   PMID:92161;   Wikipedia:Sodium_aurothiomalate


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sodium aurothiomalate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ackr3 atypical chemokine receptor 3 decreases expression ISO Gold Sodium Thiomalate results in decreased expression of ACKR3 mRNA CTD PMID:19192274 NCBI chr 9:98,247,300...98,258,877
Ensembl chr 9:98,246,605...98,260,214 		JBrowse link
G Adora2a adenosine A2a receptor decreases expression ISO Gold Sodium Thiomalate results in decreased expression of ADORA2A mRNA CTD PMID:19192274 NCBI chr20:13,315,270...13,332,802
Ensembl chr20:13,315,270...13,332,802 		JBrowse link
G Amigo2 adhesion molecule with Ig like domain 2 decreases expression ISO Gold Sodium Thiomalate results in decreased expression of AMIGO2 mRNA CTD PMID:19192274 NCBI chr 7:130,270,639...130,273,735
Ensembl chr 7:130,270,554...130,282,218 		JBrowse link
G Antxr1 ANTXR cell adhesion molecule 1 increases expression ISO Gold Sodium Thiomalate results in increased expression of ANTXR1 mRNA CTD PMID:19192274 NCBI chr 4:121,148,102...121,335,549
Ensembl chr 4:121,148,103...121,336,892 		JBrowse link
G Aox1 aldehyde oxidase 1 increases expression ISO Gold Sodium Thiomalate results in increased expression of AOX1 mRNA CTD PMID:19192274 NCBI chr 9:67,073,831...67,152,980
Ensembl chr 9:67,073,821...67,152,980 		JBrowse link
G Bcl2a1 BCL2-related protein A1 decreases expression ISO Gold Sodium Thiomalate results in decreased expression of BCL2A1 mRNA CTD PMID:19192274 NCBI chr 8:98,596,806...98,604,890
Ensembl chr 8:98,596,650...98,604,890 		JBrowse link
G Bst2 bone marrow stromal cell antigen 2 decreases expression ISO Gold Sodium Thiomalate results in decreased expression of BST2 mRNA CTD PMID:19192274 NCBI chr16:18,250,593...18,254,967
Ensembl chr16:18,251,847...18,254,967 		JBrowse link
G Ccl20 C-C motif chemokine ligand 20 decreases expression ISO Gold Sodium Thiomalate results in decreased expression of CCL20 mRNA; Gold Sodium Thiomalate results in decreased expression of CCL20 protein CTD PMID:19192274 NCBI chr 9:91,837,139...91,839,736
Ensembl chr 9:91,836,946...91,839,736 		JBrowse link
G Ccn1 cellular communication network factor 1 increases expression ISO Gold Sodium Thiomalate results in increased expression of CCN1 mRNA CTD PMID:19192274 NCBI chr 2:237,222,730...237,225,689
Ensembl chr 2:237,222,432...237,225,883 		JBrowse link
G Ccn5 cellular communication network factor 5 increases expression ISO Gold Sodium Thiomalate results in increased expression of CCN5 mRNA CTD PMID:19192274 NCBI chr 3:172,910,670...172,922,064
Ensembl chr 3:172,910,681...172,922,062 		JBrowse link
G Cd28 Cd28 molecule multiple interactions
affects response to substance 		ISO CD28 protein affects the reaction [Gold Sodium Thiomalate results in decreased activity of FBL protein]
CD28 protein affects the susceptibility to Gold Sodium Thiomalate 		CTD PMID:19077085 NCBI chr 9:69,660,316...69,689,192
Ensembl chr 9:69,545,326...69,689,192 		JBrowse link
G Chuk component of inhibitor of nuclear factor kappa B kinase complex multiple interactions ISO Gold Sodium Thiomalate inhibits the reaction [Lipopolysaccharides results in increased activity of CHUK protein] CTD PMID:10820281 NCBI chr 1:252,908,748...252,944,273
Ensembl chr 1:252,908,749...252,944,273 		JBrowse link
G Clgn calmegin decreases expression ISO Gold Sodium Thiomalate results in decreased expression of CLGN mRNA CTD PMID:19192274 NCBI chr19:41,601,568...41,633,207
Ensembl chr19:41,601,568...41,633,325 		JBrowse link
G Col1a1 collagen type I alpha 1 chain increases expression ISO Gold Sodium Thiomalate results in increased expression of COL1A1 mRNA CTD PMID:19192274 NCBI chr10:80,380,458...80,397,461
Ensembl chr10:80,380,453...80,397,460 		JBrowse link
G Colec12 collectin sub-family member 12 increases expression ISO Gold Sodium Thiomalate results in increased expression of COLEC12 mRNA CTD PMID:19192274 NCBI chr18:1,005,787...1,193,455
Ensembl chr18:1,005,741...1,195,297 		JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 decreases expression ISO Gold Sodium Thiomalate results in decreased expression of CXCL1 mRNA CTD PMID:19192274 NCBI chr14:17,477,542...17,479,321
Ensembl chr14:17,477,549...17,479,811 		JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 decreases expression ISO Gold Sodium Thiomalate results in decreased expression of CXCL2 mRNA CTD PMID:19192274 NCBI chr14:17,465,210...17,467,255
Ensembl chr14:17,465,242...17,467,255 		JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 decreases expression ISO Gold Sodium Thiomalate results in decreased expression of CXCL1 mRNA CTD PMID:19192274 NCBI chr14:17,571,900...17,573,624
Ensembl chr14:17,571,900...17,573,624 		JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 decreases expression ISO Gold Sodium Thiomalate results in decreased expression of CXCR4 mRNA CTD PMID:19192274 NCBI chr13:42,630,383...42,634,288
Ensembl chr13:42,630,104...42,634,459 		JBrowse link
G Ddx10 DEAD-box helicase 10 increases expression ISO Gold Sodium Thiomalate results in increased expression of DDX10 mRNA CTD PMID:19192274 NCBI chr 8:62,384,876...62,539,585
Ensembl chr 8:62,384,876...62,539,585 		JBrowse link
G Dio1 iodothyronine deiodinase 1 decreases activity ISO Gold Sodium Thiomalate results in decreased activity of DIO1 protein CTD PMID:34662569 NCBI chr 5:127,303,089...127,319,784
Ensembl chr 5:127,303,083...127,319,771 		JBrowse link
G Efemp1 EGF containing fibulin extracellular matrix protein 1 increases expression ISO Gold Sodium Thiomalate results in increased expression of EFEMP1 mRNA CTD PMID:19192274 NCBI chr14:106,811,769...106,890,961
Ensembl chr14:106,802,304...106,892,808 		JBrowse link
G Enpp2 ectonucleotide pyrophosphatase/phosphodiesterase 2 increases expression ISO Gold Sodium Thiomalate results in increased expression of ENPP2 mRNA CTD PMID:19192274 NCBI chr 7:88,092,140...88,214,758
Ensembl chr 7:88,092,140...88,214,957 		JBrowse link
G Entpd3 ectonucleoside triphosphate diphosphohydrolase 3 increases expression ISO Gold Sodium Thiomalate results in increased expression of ENTPD3 mRNA CTD PMID:19192274 NCBI chr 8:129,124,540...129,155,528
Ensembl chr 8:129,124,709...129,156,252 		JBrowse link
G Fbl fibrillarin affects localization
multiple interactions
decreases activity 		ISO Gold Sodium Thiomalate affects the localization of FBL protein
CD28 protein affects the reaction [Gold Sodium Thiomalate results in decreased activity of FBL protein]; IFNG protein affects the reaction [Gold Sodium Thiomalate results in decreased activity of FBL protein]; IL4 protein affects the reaction [Gold Sodium Thiomalate results in decreased activity of FBL protein]; IL6 protein affects the reaction [Gold Sodium Thiomalate results in decreased activity of FBL protein] 		CTD PMID:10942594 PMID:19077085 NCBI chr 1:92,597,407...92,606,507
Ensembl chr 1:92,597,258...92,606,506 		JBrowse link
G Fbln1 fibulin 1 increases expression ISO Gold Sodium Thiomalate results in increased expression of FBLN1 mRNA CTD PMID:19192274 NCBI chr 7:118,190,347...118,269,965
Ensembl chr 7:118,190,478...118,269,965 		JBrowse link
G Fgf7 fibroblast growth factor 7 increases expression ISO Gold Sodium Thiomalate results in increased expression of FGF7 mRNA CTD PMID:19192274 NCBI chr 3:133,734,557...133,786,678
Ensembl chr 3:133,734,673...133,786,328 		JBrowse link
G Gbp1 guanylate binding protein 1 decreases expression ISO Gold Sodium Thiomalate results in decreased expression of GBP1 mRNA CTD PMID:19192274 NCBI chr 2:234,071,366...234,106,012
Ensembl chr 2:234,190,708...234,206,802
Ensembl chr 2:234,190,708...234,206,802 		JBrowse link
G Gpm6b glycoprotein m6b increases expression ISO Gold Sodium Thiomalate results in increased expression of GPM6B mRNA CTD PMID:19192274 NCBI chr  X:31,689,485...31,836,199
Ensembl chr  X:31,690,359...31,733,272 		JBrowse link
G Gsdme gasdermin E decreases expression ISO Gold Sodium Thiomalate results in decreased expression of GSDME mRNA CTD PMID:19192274 NCBI chr 4:80,590,344...80,651,943
Ensembl chr 4:80,588,614...80,641,525 		JBrowse link
G Herc6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 decreases expression ISO Gold Sodium Thiomalate results in decreased expression of HERC6 mRNA CTD PMID:19192274 NCBI chr 4:88,854,612...88,897,043
Ensembl chr 4:88,854,640...88,896,993 		JBrowse link
G Hilpda hypoxia inducible lipid droplet-associated decreases expression ISO Gold Sodium Thiomalate results in decreased expression of HILPDA mRNA CTD PMID:19192274 NCBI chr 4:58,836,463...58,839,423
Ensembl chr 4:58,836,463...58,839,423 		JBrowse link
G Hsd11b1 hydroxysteroid 11-beta dehydrogenase 1 decreases expression ISO Gold Sodium Thiomalate results in decreased expression of HSD11B1 mRNA CTD PMID:19192274 NCBI chr13:107,277,526...107,327,462
Ensembl chr13:107,257,239...107,327,432 		JBrowse link
G Ifi27 interferon, alpha-inducible protein 27 decreases expression ISO Gold Sodium Thiomalate results in decreased expression of IFI27 mRNA CTD PMID:19192274 NCBI chr 6:128,355,312...128,361,783
Ensembl chr 6:128,355,079...128,361,781 		JBrowse link
G Ifi35 interferon-induced protein 35 decreases expression ISO Gold Sodium Thiomalate results in decreased expression of IFI35 mRNA CTD PMID:19192274 NCBI chr10:86,881,270...86,889,523
Ensembl chr10:86,887,122...86,889,750 		JBrowse link
G Ifi44 interferon-induced protein 44 decreases expression ISO Gold Sodium Thiomalate results in decreased expression of IFI44 mRNA CTD PMID:19192274 NCBI chr 2:243,286,050...243,303,869
Ensembl chr 2:243,286,052...243,306,877 		JBrowse link
G Ifi44l interferon-induced protein 44-like decreases expression ISO Gold Sodium Thiomalate results in decreased expression of IFI44L mRNA CTD PMID:19192274 NCBI chr 2:243,328,629...243,366,404
Ensembl chr 2:243,328,723...243,366,404 		JBrowse link
G Ifih1 interferon induced with helicase C domain 1 decreases expression ISO Gold Sodium Thiomalate results in decreased expression of IFIH1 mRNA CTD PMID:19192274 NCBI chr 3:67,635,924...67,683,968
Ensembl chr 3:67,637,545...67,683,968 		JBrowse link
G Ifit3 interferon-induced protein with tetratricopeptide repeats 3 decreases expression ISO Gold Sodium Thiomalate results in decreased expression of IFIT3 mRNA CTD PMID:19192274 NCBI chr 1:241,527,326...241,532,469
Ensembl chr 1:241,526,880...241,532,521 		JBrowse link
G Ifng interferon gamma multiple interactions
affects response to substance 		ISO IFNG protein affects the reaction [Gold Sodium Thiomalate results in decreased activity of FBL protein]
IFNG protein affects the susceptibility to Gold Sodium Thiomalate 		CTD PMID:19077085 NCBI chr 7:55,789,180...55,793,216
Ensembl chr 7:55,761,736...55,793,216 		JBrowse link
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta multiple interactions ISO Gold Sodium Thiomalate inhibits the reaction [Lipopolysaccharides results in increased activity of IKBKB protein] CTD PMID:10820281 NCBI chr16:76,021,968...76,075,717
Ensembl chr16:76,022,008...76,081,911 		JBrowse link
G Il10 interleukin 10 multiple interactions ISO [Gold Sodium Thiomalate co-treated with mercury nitrate analog] results in increased expression of IL10 protein CTD PMID:11824965 NCBI chr13:45,024,921...45,029,586
Ensembl chr13:45,025,087...45,029,580 		JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO Gold Sodium Thiomalate inhibits the reaction [[IL1B protein results in increased expression of NOS2 protein] which results in increased chemical synthesis of Nitric Oxide]; Gold Sodium Thiomalate inhibits the reaction [IL1B protein results in increased expression of PTGES] CTD PMID:16393772 PMID:25314295 NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601 		JBrowse link
G Il1rn interleukin 1 receptor antagonist decreases expression ISO Gold Sodium Thiomalate results in decreased expression of IL1RN mRNA CTD PMID:19192274 NCBI chr 3:27,509,836...27,525,738
Ensembl chr 3:27,509,798...27,525,732 		JBrowse link
G Il23a interleukin 23 subunit alpha decreases expression ISO Gold Sodium Thiomalate results in decreased expression of IL23A mRNA CTD PMID:19192274 NCBI chr 7:1,306,320...1,308,434
Ensembl chr 7:1,306,320...1,308,434 		JBrowse link
G Il4 interleukin 4 multiple interactions
affects response to substance 		ISO IL4 protein affects the reaction [Gold Sodium Thiomalate results in decreased activity of FBL protein]
IL4 protein affects the susceptibility to Gold Sodium Thiomalate 		CTD PMID:19077085 NCBI chr10:38,272,003...38,277,549
Ensembl chr10:38,272,003...38,277,549 		JBrowse link
G Il6 interleukin 6 multiple interactions
affects response to substance
decreases expression 		ISO [Gold Sodium Thiomalate co-treated with mercury nitrate analog] results in increased expression of IL6 protein
IL6 protein affects the reaction [Gold Sodium Thiomalate results in decreased activity of FBL protein]
IL6 protein affects the susceptibility to Gold Sodium Thiomalate
Gold Sodium Thiomalate results in decreased expression of IL6 mRNA; Gold Sodium Thiomalate results in decreased expression of IL6 protein 		CTD PMID:11824965 PMID:19077085 PMID:19192274 NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610 		JBrowse link
G Irf7 interferon regulatory factor 7 decreases expression ISO Gold Sodium Thiomalate results in decreased expression of IRF7 mRNA CTD PMID:19192274 NCBI chr 1:205,796,956...205,800,543
Ensembl chr 1:205,796,959...205,800,023 		JBrowse link
G Isg15 ISG15 ubiquitin-like modifier decreases expression ISO Gold Sodium Thiomalate results in decreased expression of ISG15 mRNA CTD PMID:19192274 NCBI chr 5:172,066,369...172,067,656
Ensembl chr 5:172,066,369...172,067,656 		JBrowse link
G Isg20 interferon stimulated exonuclease gene 20 decreases expression ISO Gold Sodium Thiomalate results in decreased expression of ISG20 mRNA CTD PMID:19192274 NCBI chr 1:142,234,729...142,246,403
Ensembl chr 1:142,236,137...142,246,401 		JBrowse link
G Lamb3 laminin subunit beta 3 decreases expression ISO Gold Sodium Thiomalate results in decreased expression of LAMB3 mRNA CTD PMID:19192274 NCBI chr13:107,362,514...107,404,081
Ensembl chr13:107,322,526...107,404,081 		JBrowse link
G Lxn latexin increases expression ISO Gold Sodium Thiomalate results in increased expression of LXN mRNA CTD PMID:19192274 NCBI chr 2:154,037,604...154,043,473
Ensembl chr 2:154,037,292...154,043,488 		JBrowse link
G Ly6e lymphocyte antigen 6 family member E decreases expression ISO Gold Sodium Thiomalate results in decreased expression of LY6E mRNA CTD PMID:19192274 NCBI chr 7:108,815,970...108,820,444
Ensembl chr 7:108,816,887...108,820,443 		JBrowse link
G Marcks myristoylated alanine rich protein kinase C substrate decreases expression ISO Gold Sodium Thiomalate results in decreased expression of MARCKS mRNA CTD PMID:19192274 NCBI chr20:42,240,185...42,245,882
Ensembl chr20:42,240,185...42,245,882 		JBrowse link
G Met MET proto-oncogene, receptor tyrosine kinase decreases expression ISO Gold Sodium Thiomalate results in decreased expression of MET mRNA CTD PMID:19192274 NCBI chr 4:46,756,823...46,864,041
Ensembl chr 4:46,756,506...46,870,821 		JBrowse link
G Mir99b microRNA 99b multiple interactions ISO Gold Sodium Thiomalate inhibits the reaction [Lipopolysaccharides results in increased expression of MIR99B mRNA] CTD PMID:33109608 NCBI chr 1:67,350,064...67,350,133
Ensembl chr 1:67,350,060...67,350,139 		JBrowse link
G Mmp10 matrix metallopeptidase 10 decreases expression ISO Gold Sodium Thiomalate results in decreased expression of MMP10 mRNA CTD PMID:19192274 NCBI chr 8:12,974,707...12,982,613
Ensembl chr 8:12,974,707...12,982,613 		JBrowse link
G Mx1 MX dynamin like GTPase 1 decreases expression ISO Gold Sodium Thiomalate results in decreased expression of MX1 mRNA CTD PMID:19192274 NCBI chr11:50,269,056...50,294,699
Ensembl chr11:50,269,057...50,292,904 		JBrowse link
G Ndufa4l2 NDUFA4, mitochondrial complex associated like 2 decreases expression ISO Gold Sodium Thiomalate results in decreased expression of NDUFA4L2 mRNA CTD PMID:19192274 NCBI chr 7:65,242,169...65,244,296
Ensembl chr 7:65,242,135...65,244,277 		JBrowse link
G Nmb neuromedin B decreases expression ISO Gold Sodium Thiomalate results in decreased expression of NMB mRNA CTD PMID:19192274 NCBI chr 1:144,278,678...144,290,523
Ensembl chr 1:144,278,453...144,281,422 		JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO Gold Sodium Thiomalate inhibits the reaction [[IL1B protein results in increased expression of NOS2 protein] which results in increased chemical synthesis of Nitric Oxide] CTD PMID:16393772 NCBI chr10:64,313,335...64,349,221
Ensembl chr10:64,313,335...64,401,880 		JBrowse link
G Nr4a3 nuclear receptor subfamily 4, group A, member 3 decreases expression ISO Gold Sodium Thiomalate results in decreased expression of NR4A3 mRNA CTD PMID:19192274 NCBI chr 5:67,157,141...67,198,287
Ensembl chr 5:67,157,375...67,198,285 		JBrowse link
G Oas1a 2'-5' oligoadenylate synthetase 1A decreases expression ISO Gold Sodium Thiomalate results in decreased expression of OAS1 mRNA CTD PMID:19192274 NCBI chr12:41,330,423...41,341,130
Ensembl chr12:41,285,211...41,341,128 		JBrowse link
G Oasl 2'-5'-oligoadenylate synthetase-like decreases expression ISO Gold Sodium Thiomalate results in decreased expression of OASL mRNA CTD PMID:19192274 NCBI chr12:47,343,551...47,356,509
Ensembl chr12:47,343,551...47,356,483 		JBrowse link
G Olfml2b olfactomedin-like 2B increases expression ISO Gold Sodium Thiomalate results in increased expression of OLFML2B mRNA CTD PMID:19192274 NCBI chr13:85,402,151...85,439,342
Ensembl chr13:85,402,169...85,439,342 		JBrowse link
G Phgdh phosphoglycerate dehydrogenase decreases expression ISO Gold Sodium Thiomalate results in decreased expression of PHGDH mRNA CTD PMID:19192274 NCBI chr 2:188,595,700...188,624,789
Ensembl chr 2:188,595,700...188,624,789 		JBrowse link
G Plpp3 phospholipid phosphatase 3 decreases expression ISO Gold Sodium Thiomalate results in decreased expression of PLPP3 mRNA CTD PMID:19192274 NCBI chr 5:125,156,000...125,231,119
Ensembl chr 5:125,155,945...125,235,667 		JBrowse link
G Ppp4r2 protein phosphatase 4, regulatory subunit 2 increases expression ISO Gold Sodium Thiomalate results in increased expression of PPP4R2 mRNA CTD PMID:19192274 NCBI chr 4:135,010,919...135,051,844
Ensembl chr 4:135,010,919...135,051,844 		JBrowse link
G Ptges prostaglandin E synthase multiple interactions ISO Gold Sodium Thiomalate inhibits the reaction [IL1B protein results in increased expression of PTGES] CTD PMID:25314295 NCBI chr 3:34,575,643...34,586,987
Ensembl chr 3:34,575,639...34,586,995 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 decreases expression ISO Gold Sodium Thiomalate results in decreased expression of PTGS2 mRNA CTD PMID:19192274 NCBI chr13:64,714,063...64,722,320
Ensembl chr13:64,713,619...64,722,320 		JBrowse link
G Rarres1 retinoic acid receptor responder 1 increases expression ISO Gold Sodium Thiomalate results in increased expression of RARRES1 mRNA CTD PMID:19192274 NCBI chr 2:154,059,761...154,094,021
Ensembl chr 2:154,059,761...154,094,024 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO Gold Sodium Thiomalate inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of RELA protein] CTD PMID:33109608 NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:212,333,035...212,364,817 		JBrowse link
G Rgs4 regulator of G-protein signaling 4 decreases expression ISO Gold Sodium Thiomalate results in decreased expression of RGS4 mRNA CTD PMID:19192274 NCBI chr13:84,469,593...84,475,884
Ensembl chr13:84,469,593...84,475,884 		JBrowse link
G Rig1 RNA sensor RIG-1 decreases expression ISO Gold Sodium Thiomalate results in decreased expression of RIGI mRNA CTD PMID:19192274 NCBI chr 5:60,117,398...60,165,995
Ensembl chr 5:60,117,398...60,165,995 		JBrowse link
G Ripk2 receptor-interacting serine-threonine kinase 2 decreases expression ISO Gold Sodium Thiomalate results in decreased expression of RIPK2 mRNA CTD PMID:19192274 NCBI chr 5:34,428,573...34,459,808
Ensembl chr 5:34,428,573...34,459,663 		JBrowse link
G Rnf19b ring finger protein 19B decreases expression ISO Gold Sodium Thiomalate results in decreased expression of RNF19B mRNA CTD PMID:19192274 NCBI chr 5:146,690,453...146,715,729
Ensembl chr 5:146,690,577...146,714,394 		JBrowse link
G Rsad2 radical S-adenosyl methionine domain containing 2 decreases expression ISO Gold Sodium Thiomalate results in decreased expression of RSAD2 mRNA CTD PMID:19192274 NCBI chr 6:48,774,985...48,788,245
Ensembl chr 6:48,774,985...48,788,320 		JBrowse link
G Slc7a11 solute carrier family 7 member 11 decreases expression ISO Gold Sodium Thiomalate results in decreased expression of SLC7A11 mRNA CTD PMID:19192274 NCBI chr 2:136,532,912...136,668,560
Ensembl chr 2:136,532,246...136,695,695 		JBrowse link
G Sms spermine synthase decreases expression ISO Gold Sodium Thiomalate results in decreased expression of SMS mRNA CTD PMID:19192274 NCBI chr  X:41,331,693...41,387,713
Ensembl chr  X:41,331,799...41,387,712 		JBrowse link
G Sod2 superoxide dismutase 2 decreases expression ISO Gold Sodium Thiomalate results in decreased expression of SOD2 mRNA CTD PMID:19192274 NCBI chr 1:50,043,323...50,050,168
Ensembl chr 1:50,043,325...50,050,168 		JBrowse link
G Spon1 spondin 1 increases expression ISO Gold Sodium Thiomalate results in increased expression of SPON1 mRNA CTD PMID:19192274 NCBI chr 1:177,363,526...177,662,689
Ensembl chr 1:177,363,197...177,662,676 		JBrowse link
G Stat1 signal transducer and activator of transcription 1 decreases expression ISO Gold Sodium Thiomalate results in decreased expression of STAT1 mRNA CTD PMID:19192274 NCBI chr 9:56,911,522...56,951,926
Ensembl chr 9:56,911,523...57,077,346 		JBrowse link
G Sts steroid sulfatase increases expression ISO Gold Sodium Thiomalate results in increased expression of STS mRNA CTD PMID:19192274 NCBI chr  X:46,102,524...46,110,868
Ensembl chr  X:46,102,548...46,111,104 		JBrowse link
G Thbs1 thrombospondin 1 increases expression ISO Gold Sodium Thiomalate results in increased expression of THBS1 mRNA CTD PMID:19192274 NCBI chr 3:125,510,250...125,525,402
Ensembl chr 3:125,510,250...125,525,402 		JBrowse link
G Thbs2 thrombospondin 2 increases expression ISO Gold Sodium Thiomalate results in increased expression of THBS2 mRNA CTD PMID:19192274 NCBI chr 1:64,343,523...64,372,918
Ensembl chr 1:64,343,523...64,372,918 		JBrowse link
G Tlr2 toll-like receptor 2 decreases expression ISO Gold Sodium Thiomalate results in decreased expression of TLR2 mRNA CTD PMID:19192274 NCBI chr 2:171,499,189...171,504,831
Ensembl chr 2:171,497,060...171,520,194 		JBrowse link
G Tnfaip2 TNF alpha induced protein 2 decreases expression ISO Gold Sodium Thiomalate results in decreased expression of TNFAIP2 mRNA CTD PMID:19192274 NCBI chr 6:136,297,388...136,311,106
Ensembl chr 6:136,298,082...136,311,106 		JBrowse link
G Txnip thioredoxin interacting protein increases expression ISO Gold Sodium Thiomalate results in increased expression of TXNIP mRNA CTD PMID:19192274 NCBI chr 2:186,781,933...186,785,736
Ensembl chr 2:186,781,163...186,785,731 		JBrowse link
G Txnrd1 thioredoxin reductase 1 multiple interactions
decreases activity 		ISO
EXP 		Gold Sodium Thiomalate inhibits the reaction [TXNRD1 protein affects the metabolism of Dithionitrobenzoic Acid]
Gold Sodium Thiomalate results in decreased activity of TXNRD1 protein 		CTD PMID:16510263 PMID:17229725 NCBI chr 7:22,717,620...22,802,553
Ensembl chr 7:22,719,317...22,739,817 		JBrowse link
G Txnrd2 thioredoxin reductase 2 decreases activity EXP Gold Sodium Thiomalate results in decreased activity of TXNRD2 protein CTD PMID:15458826 NCBI chr11:96,024,321...96,072,475
Ensembl chr11:96,024,324...96,072,475 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20862
    chemical entity 20860
      chemical substance 14605
        mixture 13923
          sodium aurothiomalate 90
Path 2
Term Annotations click to browse term
  CHEBI ontology 20862
    subatomic particle 20860
      composite particle 20860
        hadron 20860
          baryon 20860
            nucleon 20860
              atomic nucleus 20860
                atom 20860
                  main group element atom 20781
                    p-block element atom 20781
                      carbon group element atom 20715
                        carbon atom 20710
                          organic molecular entity 20710
                            organic ion 11559
                              organic anion 6933
                                carboxylic acid anion 2620
                                  dicarboxylic acid anion 255
                                    dicarboxylic acid dianion 255
                                      C4-dicarboxylate 90
                                        aurothiomalate(2-) 90
                                          disodium aurothiomalate 90
                                            sodium aurothiomalate 90
paths to the root