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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:topoisomerase IV inhibitor
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Accession:CHEBI:53559 term browser browse the term
Definition:A topoisomerase inhibitor that inhibits DNA topoisomerase IV, which catalyses ATP-dependent breakage of both strands of DNA, passage of the unbroken strands through the breaks, and rejoining of the broken strands.
Synonyms:related_synonym: topoisomerase IV inhibitors

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  CHEBI ontology 2
    role 2
      biological role 2
        biochemical role 2
          enzyme inhibitor 2
            EC 5.* (isomerase) inhibitor 0
              EC 5.99.* (other isomerases) inhibitor 0
                EC 5.99.1.* (miscellaneous isomerase) inhibitor 0
                  topoisomerase inhibitor 0
                    topoisomerase IV inhibitor 0
                      ciprofloxacin + 0
                      ciprofloxacin dihydrochloride 0
                      ciprofloxacin hydrochloride (anhydrous) + 0
                      ciprofloxacin hydrochloride hydrate 0
                      coumermycin A1 0
                      dextrofloxacin + 0
                      fleroxacin 0
                      flumequine 0
                      gemifloxacin + 0
                      gemifloxacin mesylate 0
                      levofloxacin + 0
                      ofloxacin 0
                      tosufloxacin 0
                      tosufloxacin tosylate + 0
                      tosufloxacin tosylate hydrate 0
                      trovafloxacin 0
                      trovafloxacin mesylate 0
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