|
G |
Acan |
aggrecan |
increases expression |
ISO |
alginic acid results in increased expression of ACAN mRNA |
CTD |
PMID:16371897 |
|
NCBI chr 1:132,981,582...133,044,416
Ensembl chr 1:132,981,582...133,043,627
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G |
Atg12 |
autophagy related 12 |
increases expression |
ISO |
Alginic Acid results in increased expression of ATG12 protein |
CTD |
PMID:35066102 |
|
NCBI chr18:39,452,247...39,462,424
Ensembl chr18:39,452,191...39,462,418
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G |
Atg7 |
autophagy related 7 |
increases expression |
ISO |
Alginic Acid results in increased expression of ATG7 protein |
CTD |
PMID:35066102 |
|
NCBI chr 4:147,718,663...147,925,656
Ensembl chr 4:147,718,752...147,925,593
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G |
Bcl2 |
BCL2, apoptosis regulator |
decreases expression |
ISO |
Alginic Acid results in decreased expression of BCL2 protein |
CTD |
PMID:35066102 |
|
NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743 Ensembl chr13:22,684,989...22,853,743
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G |
Bcl2l1 |
Bcl2-like 1 |
decreases expression |
ISO |
Alginic Acid results in decreased expression of BCL2L1 protein |
CTD |
PMID:35066102 |
|
NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
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G |
Becn1 |
beclin 1 |
increases expression |
ISO |
Alginic Acid results in increased expression of BECN1 protein |
CTD |
PMID:35066102 |
|
NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742
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G |
Casp3 |
caspase 3 |
increases expression increases cleavage |
ISO |
Alginic Acid results in increased expression of CASP3 protein Alginic Acid results in increased cleavage of CASP3 protein |
CTD |
PMID:35066102 |
|
NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
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|
G |
Casp8 |
caspase 8 |
multiple interactions |
ISO |
Alginic Acid results in increased expression of and results in increased cleavage of CASP8 protein |
CTD |
PMID:35066102 |
|
NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
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|
G |
Casp9 |
caspase 9 |
increases expression |
ISO |
Alginic Acid results in increased expression of CASP9 protein |
CTD |
PMID:35066102 |
|
NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
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G |
Cat |
catalase |
decreases expression |
ISO |
Alginic Acid results in decreased expression of CAT protein |
CTD |
PMID:35066102 |
|
NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
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|
G |
Col10a1 |
collagen type X alpha 1 chain |
increases expression |
ISO |
alginic acid results in increased expression of COL10A1 mRNA |
CTD |
PMID:16371897 |
|
NCBI chr20:38,183,103...38,189,488
Ensembl chr20:38,182,494...38,189,494
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G |
Cyp17a1 |
cytochrome P450, family 17, subfamily a, polypeptide 1 |
increases expression |
ISO |
Alginic Acid results in increased expression of CYP17A1 protein |
CTD |
PMID:35066102 |
|
NCBI chr 1:245,535,462...245,543,148
Ensembl chr 1:245,535,462...245,541,573
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|
G |
Cyp19a1 |
cytochrome P450, family 19, subfamily a, polypeptide 1 |
decreases expression |
ISO |
Alginic Acid results in decreased expression of CYP19A1 protein |
CTD |
PMID:35066102 |
|
NCBI chr 8:54,552,978...54,580,375
Ensembl chr 8:54,553,165...54,580,758
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G |
Fshr |
follicle stimulating hormone receptor |
decreases expression |
ISO |
Alginic Acid results in decreased expression of FSHR protein |
CTD |
PMID:35066102 |
|
NCBI chr 6:5,198,825...5,406,785
Ensembl chr 6:5,198,825...5,406,785
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G |
Gpx5 |
glutathione peroxidase 5 |
decreases expression |
ISO |
Alginic Acid results in decreased expression of GPX5 protein |
CTD |
PMID:35066102 |
|
NCBI chr17:43,436,126...43,443,074
Ensembl chr17:43,416,340...43,443,074
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G |
Icam1 |
intercellular adhesion molecule 1 |
multiple interactions |
ISO |
alginic acid inhibits the reaction [TNF protein results in increased expression of ICAM1 protein] |
CTD |
PMID:12723939 |
|
NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
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|
G |
Map1lc3b |
microtubule-associated protein 1 light chain 3 beta |
increases lipidation |
ISO |
Alginic Acid results in increased lipidation of MAP1LC3B protein |
CTD |
PMID:35066102 |
|
NCBI chr19:49,665,795...49,673,655
Ensembl chr19:49,665,791...49,677,690
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|
G |
Parp1 |
poly (ADP-ribose) polymerase 1 |
multiple interactions |
ISO |
Alginic Acid results in increased expression of and results in increased cleavage of PARP1 protein |
CTD |
PMID:35066102 |
|
NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
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G |
Rab7a |
RAB7A, member RAS oncogene family |
increases expression |
ISO |
Alginic Acid results in increased expression of RAB7 protein |
CTD |
PMID:35066102 |
|
NCBI chr 4:120,461,966...120,510,756
Ensembl chr 4:120,461,963...120,506,889
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|
G |
Sod1 |
superoxide dismutase 1 |
decreases expression |
ISO |
Alginic Acid results in decreased expression of SOD1 protein |
CTD |
PMID:35066102 |
|
NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
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G |
Sod2 |
superoxide dismutase 2 |
decreases expression |
ISO |
Alginic Acid results in decreased expression of SOD2 protein |
CTD |
PMID:35066102 |
|
NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
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G |
Sqstm1 |
sequestosome 1 |
decreases expression |
ISO |
Alginic Acid results in decreased expression of SQSTM1 protein |
CTD |
PMID:35066102 |
|
NCBI chr10:34,525,517...34,536,670
Ensembl chr10:34,525,519...34,536,673
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G |
Star |
steroidogenic acute regulatory protein |
decreases expression |
ISO |
Alginic Acid results in decreased expression of STAR protein |
CTD |
PMID:35066102 |
|
NCBI chr16:66,267,094...66,274,368
Ensembl chr16:66,264,807...66,271,672
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|
G |
Tnf |
tumor necrosis factor |
multiple interactions |
ISO |
alginic acid inhibits the reaction [TNF protein results in increased abundance of Hydrogen Peroxide]; alginic acid inhibits the reaction [TNF protein results in increased abundance of Nitric Oxide]; alginic acid inhibits the reaction [TNF protein results in increased expression of ICAM1 protein] |
CTD |
PMID:12723939 |
|
NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
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|
|
G |
Ccl2 |
C-C motif chemokine ligand 2 |
increases secretion |
ISO |
p-Methoxy-N-methylphenethylamine results in increased secretion of CCL2 protein |
CTD |
PMID:34826398 |
|
NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
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G |
Gusb |
glucuronidase, beta |
increases secretion |
EXP |
p-Methoxy-N-methylphenethylamine results in increased secretion of GUSB protein |
CTD |
PMID:9545557 |
|
NCBI chr12:26,701,188...26,714,718
Ensembl chr12:26,697,951...26,726,905
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|
G |
Hexa |
hexosaminidase subunit alpha |
increases secretion multiple interactions |
ISO |
p-Methoxy-N-methylphenethylamine results in increased secretion of HEXA protein Apigenin inhibits the reaction [p-Methoxy-N-methylphenethylamine results in increased secretion of HEXA protein] |
CTD |
PMID:36350155 |
|
NCBI chr 8:59,936,526...59,961,654
Ensembl chr 8:59,936,660...59,962,013
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G |
Hexb |
hexosaminidase subunit beta |
increases secretion |
ISO |
p-Methoxy-N-methylphenethylamine results in increased secretion of HEXB protein |
CTD |
PMID:34774977 |
|
NCBI chr 2:28,483,997...28,504,165
Ensembl chr 2:28,484,012...28,504,223
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|
G |
Htr1a |
5-hydroxytryptamine receptor 1A |
increases activity |
EXP |
p-Methoxy-N-methylphenethylamine results in increased activity of HTR1A protein |
CTD |
PMID:16415902 |
|
NCBI chr 2:36,693,462...36,698,026
Ensembl chr 2:36,694,174...36,695,442
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|
G |
Kit |
KIT proto-oncogene receptor tyrosine kinase |
affects response to substance |
ISO |
KIT protein affects the susceptibility to p-Methoxy-N-methylphenethylamine |
CTD |
PMID:32871113 |
|
NCBI chr14:32,547,459...32,624,694
Ensembl chr14:32,548,877...32,624,652
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|
G |
Kng1 |
kininogen 1 |
decreases activity |
ISO |
p-Methoxy-N-methylphenethylamine results in decreased activity of KNG1 protein |
CTD |
PMID:1371395 |
|
NCBI chr11:77,812,757...77,835,555
Ensembl chr11:77,812,752...77,835,555
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|
G |
Lck |
LCK proto-oncogene, Src family tyrosine kinase |
multiple interactions increases activity |
EXP |
atractylon inhibits the reaction [p-Methoxy-N-methylphenethylamine results in increased activity of LCK protein]; damnacanthal inhibits the reaction [p-Methoxy-N-methylphenethylamine results in increased activity of LCK protein]; pyeongwee-san extract inhibits the reaction [p-Methoxy-N-methylphenethylamine results in increased activity of LCK protein] |
CTD |
PMID:27553716 |
|
NCBI chr 5:141,888,318...141,916,945
Ensembl chr 5:141,888,326...141,903,794
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G |
Mapk1 |
mitogen activated protein kinase 1 |
multiple interactions increases phosphorylation |
ISO |
epigallocatechin gallate inhibits the reaction [p-Methoxy-N-methylphenethylamine results in increased phosphorylation of MAPK1 protein] |
CTD |
PMID:29402411 |
|
NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
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|
G |
Mapk3 |
mitogen activated protein kinase 3 |
multiple interactions increases phosphorylation |
ISO |
epigallocatechin gallate inhibits the reaction [p-Methoxy-N-methylphenethylamine results in increased phosphorylation of MAPK3 protein] |
CTD |
PMID:29402411 |
|
NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
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|
G |
Mrgprx2 |
MAS related GPR family member X2 |
affects response to substance |
ISO |
MRGPRX2 protein affects the susceptibility to p-Methoxy-N-methylphenethylamine |
CTD |
PMID:32871113 |
|
NCBI chr 1:98,116,192...98,135,534
|
|
G |
Nr3c1 |
nuclear receptor subfamily 3, group C, member 1 |
decreases activity |
ISO |
p-Methoxy-N-methylphenethylamine results in decreased activity of NR3C1 protein |
CTD |
PMID:7887964 |
|
NCBI chr18:31,271,681...31,393,320
Ensembl chr18:31,271,681...31,393,375
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|
G |
Tnf |
tumor necrosis factor |
increases secretion |
ISO |
p-Methoxy-N-methylphenethylamine results in increased secretion of TNF protein |
CTD |
PMID:34826398 |
|
NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
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|
G |
Tpsb2 |
tryptase beta 2 |
increases secretion |
ISO |
p-Methoxy-N-methylphenethylamine results in increased secretion of TPSB2 protein |
CTD |
PMID:34826398 |
|
NCBI chr10:14,381,779...14,383,571
Ensembl chr10:14,382,013...14,383,569
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|
G |
Adipoq |
adiponectin, C1Q and collagen domain containing |
decreases secretion multiple interactions |
EXP |
Poloxamer results in decreased secretion of ADIPOQ protein carvacrol inhibits the reaction [Poloxamer results in decreased secretion of ADIPOQ protein]; carvacrol promotes the reaction [Simvastatin inhibits the reaction [Poloxamer results in decreased secretion of ADIPOQ protein]]; Simvastatin inhibits the reaction [Poloxamer results in decreased secretion of ADIPOQ protein] |
CTD |
PMID:29071762 |
|
NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564
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|
G |
Afp |
alpha-fetoprotein |
multiple interactions |
EXP |
Poloxamer promotes the reaction [Niclosamide inhibits the reaction [Thioacetamide results in increased expression of AFP protein]] |
CTD |
PMID:32961231 |
|
NCBI chr14:17,573,412...17,591,476
Ensembl chr14:17,573,412...17,591,480
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|
G |
Casp3 |
caspase 3 |
increases expression multiple interactions |
EXP |
Poloxamer results in increased expression of CASP3 protein carvacrol inhibits the reaction [Poloxamer results in increased expression of CASP3 protein]; carvacrol inhibits the reaction [Simvastatin promotes the reaction [Poloxamer results in increased expression of CASP3 protein]]; Poloxamer promotes the reaction [Niclosamide inhibits the reaction [Thioacetamide results in decreased expression of CASP3 mRNA]]; Simvastatin promotes the reaction [Poloxamer results in increased expression of CASP3 protein] |
CTD |
PMID:29071762 PMID:32961231 |
|
NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
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G |
Cat |
catalase |
multiple interactions decreases activity |
EXP |
carvacrol inhibits the reaction [Poloxamer results in decreased activity of CAT protein]; carvacrol promotes the reaction [Simvastatin inhibits the reaction [Poloxamer results in decreased activity of CAT protein]]; Simvastatin inhibits the reaction [Poloxamer results in decreased activity of CAT protein] |
CTD |
PMID:29071762 |
|
NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
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G |
Ccnd1 |
cyclin D1 |
multiple interactions |
EXP |
Poloxamer promotes the reaction [Niclosamide inhibits the reaction [Thioacetamide results in increased expression of CCND1 mRNA]]; Poloxamer promotes the reaction [Niclosamide inhibits the reaction [Thioacetamide results in increased expression of CCND1 protein]] |
CTD |
PMID:32961231 |
|
NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
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G |
Cd68 |
Cd68 molecule |
multiple interactions |
ISO |
Poloxamer inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of CD68 mRNA] |
CTD |
PMID:32169474 |
|
NCBI chr10:54,381,814...54,383,693
Ensembl chr10:54,381,815...54,383,697
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G |
Ckm |
creatine kinase, M-type |
multiple interactions increases secretion |
EXP |
carvacrol inhibits the reaction [Poloxamer results in increased secretion of CKM protein] |
CTD |
PMID:29071762 |
|
NCBI chr 1:79,061,390...79,071,721
Ensembl chr 1:79,061,456...79,071,720
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G |
Csf1r |
colony stimulating factor 1 receptor |
multiple interactions |
ISO |
Poloxamer inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of CSF1R mRNA] |
CTD |
PMID:32169474 |
|
NCBI chr18:54,546,673...54,590,418
Ensembl chr18:54,546,659...54,590,415
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G |
Csf2ra |
colony stimulating factor 2 receptor subunit alpha |
multiple interactions |
ISO |
Poloxamer inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of CSF2RA mRNA] |
CTD |
PMID:32169474 |
|
NCBI chr14:98,089...103,261
Ensembl chr14:89,172...103,128
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G |
Ctnnb1 |
catenin beta 1 |
multiple interactions |
EXP |
Poloxamer promotes the reaction [Niclosamide inhibits the reaction [Thioacetamide results in increased expression of CTNNB1 protein]] |
CTD |
PMID:32961231 |
|
NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111
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G |
Dvl2 |
dishevelled segment polarity protein 2 |
multiple interactions |
EXP |
Poloxamer promotes the reaction [Niclosamide inhibits the reaction [Thioacetamide results in increased expression of DVL2 mRNA]] |
CTD |
PMID:32961231 |
|
NCBI chr10:54,723,356...54,732,823
Ensembl chr10:54,723,411...54,732,820
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G |
Hes1 |
hes family bHLH transcription factor 1 |
multiple interactions |
EXP |
Poloxamer promotes the reaction [Niclosamide inhibits the reaction [Thioacetamide results in increased expression of HES1 mRNA]] |
CTD |
PMID:32961231 |
|
NCBI chr11:70,705,763...70,708,176
Ensembl chr11:70,705,764...70,708,192
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G |
Hmox1 |
heme oxygenase 1 |
multiple interactions |
ISO |
[nickel monoxide co-treated with Poloxamer] results in increased expression of HMOX1 mRNA |
CTD |
PMID:25964212 |
|
NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
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G |
Icam1 |
intercellular adhesion molecule 1 |
multiple interactions |
ISO |
Poloxamer inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of ICAM1 mRNA] |
CTD |
PMID:32169474 |
|
NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
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G |
Icam2 |
intercellular adhesion molecule 2 |
multiple interactions |
ISO |
Poloxamer inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of ICAM2 mRNA] |
CTD |
PMID:32169474 |
|
NCBI chr10:91,308,608...91,319,536
Ensembl chr10:91,308,538...91,315,293
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G |
Il1b |
interleukin 1 beta |
multiple interactions |
ISO |
Poloxamer inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of IL1B mRNA] |
CTD |
PMID:32169474 |
|
NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
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G |
Il6 |
interleukin 6 |
multiple interactions |
ISO |
Poloxamer inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of IL6 mRNA] |
CTD |
PMID:32169474 |
|
NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
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G |
Itgam |
integrin subunit alpha M |
multiple interactions |
ISO |
Poloxamer inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of ITGAM mRNA] |
CTD |
PMID:32169474 |
|
NCBI chr 1:182,659,047...182,709,501
Ensembl chr 1:182,659,000...182,709,503
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G |
Lep |
leptin |
multiple interactions increases secretion |
EXP |
carvacrol inhibits the reaction [Poloxamer results in increased secretion of LEP protein]; Simvastatin inhibits the reaction [Poloxamer results in increased secretion of LEP protein] |
CTD |
PMID:29071762 |
|
NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262
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G |
Lrp5 |
LDL receptor related protein 5 |
multiple interactions |
EXP |
Poloxamer promotes the reaction [Niclosamide inhibits the reaction [Thioacetamide results in increased expression of LRP5 mRNA]] |
CTD |
PMID:32961231 |
|
NCBI chr 1:200,814,247...200,917,581
Ensembl chr 1:200,814,250...200,917,581
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G |
Lrp6 |
LDL receptor related protein 6 |
multiple interactions |
EXP |
Poloxamer promotes the reaction [Niclosamide inhibits the reaction [Thioacetamide results in increased expression of LRP6 mRNA]] |
CTD |
PMID:32961231 |
|
NCBI chr 4:167,269,856...167,400,364
Ensembl chr 4:167,270,353...167,400,497
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G |
Mb |
myoglobin |
multiple interactions increases secretion |
EXP |
carvacrol inhibits the reaction [Poloxamer results in increased secretion of MB protein]; Simvastatin inhibits the reaction [Poloxamer results in increased secretion of MB protein] |
CTD |
PMID:29071762 |
|
NCBI chr 7:108,759,903...108,767,134
Ensembl chr 7:108,759,904...108,767,383
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G |
Notch1 |
notch receptor 1 |
multiple interactions |
EXP |
Poloxamer promotes the reaction [Niclosamide inhibits the reaction [Thioacetamide results in increased expression of NOTCH1 mRNA]] |
CTD |
PMID:32961231 |
|
NCBI chr 3:9,277,955...9,323,531
Ensembl chr 3:9,278,086...9,323,531
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G |
Pnlip |
pancreatic lipase |
decreases activity |
ISO |
Poloxamer results in decreased activity of PNLIP protein |
CTD |
PMID:16872557 |
|
NCBI chr 1:257,774,012...257,811,656
Ensembl chr 1:257,798,581...257,811,654
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G |
Ptgs2 |
prostaglandin-endoperoxide synthase 2 |
multiple interactions |
ISO |
Poloxamer inhibits the reaction [Nanotubes, Carbon inhibits the reaction [endotoxin, Escherichia coli results in increased expression of PTGS2 protein]] |
CTD |
PMID:17709331 |
|
NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
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G |
Tnf |
tumor necrosis factor |
multiple interactions |
ISO |
Poloxamer inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of TNF mRNA] |
CTD |
PMID:32169474 |
|
NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
|
|
G |
Wnt3a |
Wnt family member 3A |
multiple interactions |
EXP |
Poloxamer promotes the reaction [Niclosamide inhibits the reaction [Thioacetamide results in increased expression of WNT3A mRNA]] |
CTD |
PMID:32961231 |
|
NCBI chr10:44,034,174...44,078,366
Ensembl chr10:44,034,194...44,078,324
|
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