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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:poly(vinylpyrrolidone)
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Accession:CHEBI:53248 term browser browse the term
Definition:A vinyl polymer composed of repeating -CH2-CR- units where R is a 2-oxopyrrolidin-1-yl group.
Synonyms:exact_synonym: poly[1-(2-oxopyrrolidin-1-yl)ethylene]
 related_synonym: 1-Ethenyl-2-pyrrolidinone homopolymer;   1-Ethenyl-2-pyrrolidinone polymers;   1-Vinyl-2-pyrrolidinone homopolymer;   1-Vinyl-2-pyrrolidinone polymer;   1-Vinyl-2-pyrrolidone polymer;   Crospovidonum;   Formula=(C6H9NO)n;   N-Vinyl-2-pyrrolidone polymer;   N-Vinylbutyrolactam polymer;   N-Vinylpyrrolidinone polymer;   N-Vinylpyrrolidone polymer;   PVP;   PVPON;   Polividona;   Polividone;   Poly(1-(2-oxo-1-pyrrolidinyl)ethylene);   Poly(1-ethenyl-2-pyrrolidinone);   Poly(1-vinyl-2-pyrrolidinone);   Poly(1-vinyl-2-pyrrolidinone) homopolymer;   Poly(1-vinyl-2-pyrrolidone);   Poly(1-vinylpyrrolidinone);   Poly(N-vinyl-2-pyrrolidinone);   Poly(N-vinyl-2-pyrrolidone);   Poly(N-vinylbutyrolactam);   Poly(N-vinylpyrrolidinone);   Poly-N-vinyl pyrrolidone;   Polyvidonum;   Polyvinylpyrrolidone;   Povidone;   Vinylpyrrolidinone polymer;   Vinylpyrrolidone polymer;   poly(N-vinylpyrrolidone)
 xref: Beilstein:10781921;   Beilstein:8192478;   Beilstein:8473739;   Beilstein:8473925;   CAS:9003-39-8;   Gmelin:1451700;   KEGG:C19509;   KEGG:D02295
 xref_mesh: MESH:D011205
 xref: PMID:12927801;   PMID:15137988;   PMID:16776723;   PMID:8448384;   Reaxys:18634154


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poly(vinylpyrrolidone) term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G App amyloid beta precursor protein multiple interactions ISO [Silver Compounds co-treated with Povidone] results in increased expression of APP protein CTD PMID:35697184 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561 		JBrowse link
G Atp5mc2 ATP synthase membrane subunit c locus 2 multiple interactions EXP [Silver analog co-treated with Povidone] results in decreased expression of ATP5MC2 mRNA CTD PMID:25194297 NCBI chr 7:133,791,341...133,799,713
Ensembl chr 7:133,791,342...133,799,733 		JBrowse link
G Bola3 bolA family member 3 multiple interactions EXP [Silver analog co-treated with Povidone] results in decreased expression of BOLA3 mRNA CTD PMID:25194297 NCBI chr 4:115,853,350...115,862,797
Ensembl chr 4:115,853,350...115,862,797 		JBrowse link
G Casp3 caspase 3 multiple interactions ISO [Silver co-treated with Povidone] affects the expression of CASP3 protein; [Silver co-treated with Povidone] results in decreased expression of CASP3 mRNA CTD PMID:27387714 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions ISO [Silver co-treated with Povidone] results in decreased expression of CDKN1A mRNA; [Silver co-treated with Povidone] results in decreased expression of CDKN1A protein CTD PMID:27387714 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585 		JBrowse link
G Col8a1 collagen type VIII alpha 1 chain multiple interactions EXP [Silver analog co-treated with Povidone] results in increased expression of COL8A1 mRNA CTD PMID:25194297 NCBI chr11:42,776,851...42,906,432
Ensembl chr11:42,777,628...42,906,424 		JBrowse link
G Cox17 cytochrome c oxidase copper chaperone COX17 multiple interactions EXP [Silver analog co-treated with Povidone] results in decreased expression of COX17 mRNA CTD PMID:25194297 NCBI chr11:62,400,733...62,406,507 JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions EXP [Silver analog co-treated with Povidone] results in increased expression of CYP1A1 mRNA CTD PMID:25194297 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125 		JBrowse link
G Dad1 defender against cell death 1 multiple interactions EXP [Silver analog co-treated with Povidone] results in decreased expression of DAD1 mRNA CTD PMID:25194297 NCBI chr15:27,677,286...27,697,120
Ensembl chr15:27,677,268...27,697,347 		JBrowse link
G Dlg4 discs large MAGUK scaffold protein 4 multiple interactions ISO [Silver Compounds co-treated with Povidone] results in decreased expression of DLG4 protein CTD PMID:35697184 NCBI chr10:54,740,700...54,769,097
Ensembl chr10:54,739,470...54,767,153 		JBrowse link
G Gbp2 guanylate binding protein 2 multiple interactions EXP [Silver analog co-treated with Povidone] results in decreased expression of GBP2 mRNA CTD PMID:25194297 NCBI chr 2:231,332,488...231,348,573
Ensembl chr 2:231,332,284...231,348,571 		JBrowse link
G H2ax H2A.X variant histone multiple interactions ISO [Silver co-treated with Povidone] results in increased expression of H2AX protein modified form CTD PMID:27387714 NCBI chr 8:44,671,907...44,673,262
Ensembl chr 8:44,671,786...44,673,239
Ensembl chr 4:44,671,786...44,673,239 		JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions EXP [Silver analog co-treated with Povidone] results in increased expression of HMOX1 mRNA CTD PMID:25194297 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Ifit3 interferon-induced protein with tetratricopeptide repeats 3 multiple interactions EXP [Silver analog co-treated with Povidone] results in decreased expression of IFIT3 mRNA CTD PMID:25194297 NCBI chr 1:232,114,166...232,119,311
Ensembl chr 1:232,114,166...232,119,307 		JBrowse link
G Lims1 LIM zinc finger domain containing 1 multiple interactions EXP [Silver analog co-treated with Povidone] results in increased expression of LIMS1 mRNA CTD PMID:25194297 NCBI chr20:26,309,833...26,418,511
Ensembl chr20:26,309,895...26,418,500 		JBrowse link
G Lmnb2 lamin B2 multiple interactions EXP [Silver analog co-treated with Povidone] results in decreased expression of LMNB2 mRNA CTD PMID:25194297 NCBI chr 7:8,792,628...8,808,665
Ensembl chr 7:8,789,314...8,808,665 		JBrowse link
G Map2 microtubule-associated protein 2 multiple interactions ISO [Silver Compounds co-treated with Povidone] results in decreased expression of MAP2 protein CTD PMID:35697184 NCBI chr 9:67,723,422...67,981,886
Ensembl chr 9:67,723,371...67,979,809 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO [Silver Compounds co-treated with Povidone] results in increased activity of MAPK1 protein CTD PMID:21729742 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO [Silver Compounds co-treated with Povidone] results in increased activity of MAPK3 protein CTD PMID:21729742 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Mdm2 MDM2 proto-oncogene multiple interactions ISO [Silver co-treated with Povidone] affects the expression of MDM2 protein; [Silver co-treated with Povidone] results in decreased expression of MDM2 mRNA CTD PMID:27387714 NCBI chr 7:53,290,660...53,315,205
Ensembl chr 7:53,290,664...53,314,915 		JBrowse link
G Mt1 metallothionein 1 multiple interactions EXP [Silver analog co-treated with Povidone] affects the expression of MT1A mRNA CTD PMID:25194297 NCBI chr19:10,826,032...10,827,048
Ensembl chr19:10,826,032...10,827,049
Ensembl chr17:10,826,032...10,827,049
Ensembl chr  X:10,826,032...10,827,049 		JBrowse link
G Nfix nuclear factor I X multiple interactions EXP [Silver analog co-treated with Povidone] results in increased expression of NFIX mRNA CTD PMID:25194297 NCBI chr19:23,355,388...23,450,360
Ensembl chr19:23,355,498...23,448,265 		JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 multiple interactions EXP [Silver analog co-treated with Povidone] results in increased expression of NQO1 mRNA CTD PMID:25194297 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557 		JBrowse link
G Nrm nurim multiple interactions EXP [Silver analog co-treated with Povidone] results in decreased expression of NRM mRNA CTD PMID:25194297 NCBI chr20:2,888,321...2,892,804
Ensembl chr20:2,877,567...2,891,802 		JBrowse link
G Nuak2 NUAK family kinase 2 multiple interactions EXP [Silver analog co-treated with Povidone] results in decreased expression of NUAK2 mRNA CTD PMID:25194297 NCBI chr13:43,753,454...43,770,604
Ensembl chr13:43,753,832...43,770,604 		JBrowse link
G Ocln occludin affects expression ISO Povidone affects the expression of OCLN mRNA CTD PMID:19729060 NCBI chr 2:31,657,217...31,707,466
Ensembl chr 2:31,657,220...31,764,150 		JBrowse link
G Pink1 PTEN induced kinase 1 multiple interactions ISO [Silver Compounds co-treated with Povidone] results in increased expression of PINK1 protein CTD PMID:35697184 NCBI chr 5:150,530,523...150,542,635
Ensembl chr 5:150,530,523...150,542,635 		JBrowse link
G Ppargc1a PPARG coactivator 1 alpha multiple interactions ISO [Silver Compounds co-treated with Povidone] results in decreased expression of PPARGC1A protein CTD PMID:35697184 NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656 		JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase multiple interactions ISO [Silver Compounds co-treated with Povidone] results in increased expression of PRKN protein CTD PMID:35697184 NCBI chr 1:48,688,651...49,882,520
Ensembl chr 1:48,690,556...49,882,555 		JBrowse link
G Prpf38b pre-mRNA processing factor 38B multiple interactions EXP [Silver analog co-treated with Povidone] results in decreased expression of PRPF38B mRNA CTD PMID:25194297 NCBI chr 2:196,553,224...196,562,271
Ensembl chr 2:196,553,225...196,562,250 		JBrowse link
G Prr13 proline rich 13 multiple interactions EXP [Silver analog co-treated with Povidone] results in decreased expression of PRR13 mRNA CTD PMID:25194297 NCBI chr 7:133,592,511...133,595,817
Ensembl chr 7:133,592,490...133,601,005 		JBrowse link
G Psenen presenilin enhancer gamma secretase subunit multiple interactions EXP [Silver analog co-treated with Povidone] results in decreased expression of PSENEN mRNA CTD PMID:25194297 NCBI chr 1:85,814,905...85,816,654
Ensembl chr 1:85,814,905...85,816,192 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions EXP [Silver analog co-treated with Povidone] results in increased expression of PTGS2 mRNA CTD PMID:25194297 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Ptk2 protein tyrosine kinase 2 multiple interactions ISO [Silver Compounds co-treated with Povidone] results in increased activity of PTK2 protein CTD PMID:21729742 NCBI chr 7:105,126,725...105,331,848
Ensembl chr 7:105,126,728...105,331,783 		JBrowse link
G Rab14 RAB14, member RAS oncogene family multiple interactions EXP [Silver analog co-treated with Povidone] results in increased expression of RAB14 mRNA CTD PMID:25194297 NCBI chr 3:18,501,953...18,523,253
Ensembl chr 3:18,501,963...18,523,172 		JBrowse link
G Rbm25l1 RNA binding motif protein 25-like 1 multiple interactions EXP [Silver analog co-treated with Povidone] results in increased expression of RBM25L1 mRNA CTD PMID:25194297 NCBI chr10:10,267,026...10,270,510
Ensembl chr10:10,267,260...10,269,710
Ensembl chr 6:10,267,260...10,269,710 		JBrowse link
G Samd9l sterile alpha motif domain containing 9 like multiple interactions EXP [Silver analog co-treated with Povidone] results in decreased expression of SAMD9L mRNA CTD PMID:25194297 NCBI chr 4:31,362,054...31,376,412
Ensembl chr 4:31,361,669...31,376,415 		JBrowse link
G Selenow selenoprotein W multiple interactions EXP [Silver analog co-treated with Povidone] results in decreased expression of SELENOW mRNA CTD PMID:25194297 NCBI chr 1:76,599,441...76,604,514
Ensembl chr 1:76,598,779...76,604,724
Ensembl chr 1:76,598,779...76,604,724 		JBrowse link
G Slc5a3 solute carrier family 5 member 3 multiple interactions EXP [Silver analog co-treated with Povidone] results in increased expression of SLC5A3 mRNA CTD PMID:25194297 NCBI chr11:31,313,847...31,316,293
Ensembl chr11:31,295,476...31,318,883 		JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions ISO [Silver co-treated with Povidone] results in increased expression of SOD2 mRNA; [Silver co-treated with Povidone] results in increased expression of SOD2 protein CTD PMID:27387714 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189 		JBrowse link
G Sparc secreted protein acidic and cysteine rich multiple interactions EXP [Silver analog co-treated with Povidone] results in decreased expression of SPARC mRNA CTD PMID:25194297 NCBI chr10:39,516,394...39,538,252
Ensembl chr10:39,516,406...39,538,396 		JBrowse link
G Stat2 signal transducer and activator of transcription 2 multiple interactions EXP [Silver analog co-treated with Povidone] results in decreased expression of STAT2 mRNA CTD PMID:25194297 NCBI chr 7:702,565...718,349
Ensembl chr 7:702,495...718,967 		JBrowse link
G Sv2b synaptic vesicle glycoprotein 2b multiple interactions EXP [Silver analog co-treated with Povidone] results in increased expression of SV2B mRNA CTD PMID:25194297 NCBI chr 1:128,978,471...129,152,479
Ensembl chr 1:128,978,473...129,152,479 		JBrowse link
G Syp synaptophysin multiple interactions ISO [Silver Compounds co-treated with Povidone] results in increased expression of SYP protein CTD PMID:35697184 NCBI chr  X:14,849,444...14,864,553
Ensembl chr  X:14,849,444...14,864,745 		JBrowse link
G Tiparp TCDD-inducible poly(ADP-ribose) polymerase multiple interactions EXP [Silver analog co-treated with Povidone] results in increased expression of TIPARP mRNA CTD PMID:25194297 NCBI chr 2:149,753,682...149,780,327
Ensembl chr 2:149,753,682...149,780,327 		JBrowse link
G Tmtc3 transmembrane O-mannosyltransferase targeting cadherins 3 multiple interactions EXP [Silver analog co-treated with Povidone] results in increased expression of TMTC3 mRNA CTD PMID:25194297 NCBI chr 7:35,264,886...35,310,010
Ensembl chr 7:35,264,892...35,310,385 		JBrowse link
G Tp53 tumor protein p53 multiple interactions ISO [Silver co-treated with Povidone] affects the phosphorylation of TP53 protein; [Silver co-treated with Povidone] results in decreased expression of TP53 mRNA; [Silver co-treated with Povidone] results in decreased expression of TP53 protein CTD PMID:27387714 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
G Trappc1 trafficking protein particle complex subunit 1 multiple interactions EXP [Silver analog co-treated with Povidone] results in decreased expression of TRAPPC1 mRNA CTD PMID:25194297 NCBI chr10:54,045,598...54,047,184
Ensembl chr10:54,045,537...54,047,331 		JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions ISO [Silver Compounds co-treated with Povidone] results in increased expression of VEGFA protein CTD PMID:21729742 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641 		JBrowse link
G Wdfy1 WD repeat and FYVE domain containing 1 multiple interactions EXP [Silver analog co-treated with Povidone] results in increased expression of WDFY1 mRNA CTD PMID:25194297 NCBI chr 9:81,034,852...81,092,823
Ensembl chr 9:81,034,849...81,092,775 		JBrowse link
G Zfhx3 zinc finger homeobox 3 multiple interactions EXP [Silver analog co-treated with Povidone] results in increased expression of ZFHX3 mRNA CTD PMID:25194297 NCBI chr19:36,257,196...36,886,104
Ensembl chr19:36,630,254...36,881,771 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19880
    role 19850
      application 19695
        pharmaceutical 19532
          blood substitute 61
            poly(vinylpyrrolidone) 51
              poly(vinylpyrrolidone)-coated Ag nanoparticle + 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19880
    subatomic particle 19878
      composite particle 19878
        hadron 19878
          baryon 19878
            nucleon 19878
              atomic nucleus 19878
                atom 19878
                  group 19831
                    polyatomic entity 19830
                      macromolecule 8834
                        homopolymer macromolecule 116
                          poly(alkylene) macromolecule 86
                            polyethylene macromolecule 86
                              vinyl polymer macromolecule 71
                                poly(vinylpyrrolidone) 51
                                  poly(vinylpyrrolidone)-coated Ag nanoparticle + 0
paths to the root