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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:poly(alkylene) macromolecule
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Accession:CHEBI:53225 term browser browse the term
Definition:A macromolecule composed of repeating alkane or substituted alkane units.
Synonyms:related_synonym: poly(alkene);   poly(alkene)s;   poly(alkylene);   poly(alkylene)s;   poly(olefin);   poly(olefin)s;   polyalkene;   polyalkenes;   polyalkylene;   polyalkylenes;   polyolefin;   polyolefins


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colesevelam hydrochloride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Crp C-reactive protein decreases expression ISO Colesevelam Hydrochloride results in decreased expression of CRP protein CTD PMID:16616026 NCBI chr13:85,135,384...85,175,178
Ensembl chr13:85,124,977...85,175,178 		JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase multiple interactions
increases expression		 ISO Colesevelam Hydrochloride promotes the reaction [Simvastatin results in increased expression of HMGCR mRNA]
Colesevelam Hydrochloride results in increased expression of HMGCR mRNA		 CTD PMID:22120639 NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703 		JBrowse link
G Ldlr low density lipoprotein receptor increases expression ISO Colesevelam Hydrochloride results in increased expression of LDLR mRNA CTD PMID:22120639 NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580 		JBrowse link
poly(ethylene) term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acp5 acid phosphatase 5, tartrate resistant decreases expression ISO Polyethylene results in decreased expression of ACP5 mRNA CTD PMID:15585240 NCBI chr 8:20,663,984...20,670,604
Ensembl chr 8:20,663,985...20,667,929 		JBrowse link
G Ascl1 achaete-scute family bHLH transcription factor 1 decreases expression ISO Polyethylene results in decreased expression of ASCL1 mRNA CTD PMID:23203475 NCBI chr 7:21,903,136...21,906,003
Ensembl chr 7:21,903,126...21,905,993 		JBrowse link
G Bglap bone gamma-carboxyglutamate protein decreases expression ISO Polyethylene results in decreased expression of BGLAP protein CTD PMID:10225790 NCBI chr 2:173,838,518...173,839,495
Ensembl chr 2:173,838,518...173,839,495 		JBrowse link
G Cat catalase multiple interactions ISO [[Microplastics results in increased abundance of [Polyvinyl Chloride co-treated with Polyethylene]] co-treated with [lead acetate results in increased abundance of Lead]] results in decreased expression of CAT protein; [lead acetate results in increased abundance of Lead] promotes the reaction [[Microplastics results in increased abundance of [Polyvinyl Chloride co-treated with Polyethylene]] which results in decreased expression of CAT protein]; [Microplastics results in increased abundance of [Polyvinyl Chloride co-treated with Polyethylene]] promotes the reaction [[lead acetate results in increased abundance of Lead] which results in decreased expression of CAT protein]; [Microplastics results in increased abundance of [Polyvinyl Chloride co-treated with Polyethylene]] which results in decreased expression of CAT protein CTD PMID:38180308 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Col1a1 collagen type I alpha 1 chain decreases expression ISO Polyethylene results in decreased expression of COL1A1 mRNA CTD PMID:11216681 NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624 		JBrowse link
G Csf2 colony stimulating factor 2 affects secretion ISO Polyethylene affects the secretion of CSF2 protein CTD PMID:15046894 NCBI chr10:38,386,945...38,388,926
Ensembl chr10:38,386,945...38,389,199 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit decreases expression ISO Polyethylene results in decreased expression of FOS mRNA CTD PMID:15585240 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036 		JBrowse link
G Foxg1 forkhead box G1 decreases expression ISO Polyethylene results in decreased expression of FOXG1 mRNA CTD PMID:23203475 NCBI chr 6:66,674,797...66,677,611
Ensembl chr 6:66,666,587...66,678,607 		JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions ISO [[Microplastics results in increased abundance of [Polyvinyl Chloride co-treated with Polyethylene]] co-treated with [lead acetate results in increased abundance of Lead]] results in increased expression of GPT protein CTD PMID:38180308 NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494 		JBrowse link
G Hes5 hes family bHLH transcription factor 5 decreases expression ISO Polyethylene results in decreased expression of HES5 mRNA CTD PMID:23203475 NCBI chr 5:165,522,138...165,523,684
Ensembl chr 5:165,522,234...165,523,001 		JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions ISO [[Microplastics results in increased abundance of [Polyvinyl Chloride co-treated with Polyethylene]] co-treated with [lead acetate results in increased abundance of Lead]] results in decreased expression of HMOX1 mRNA; [[Microplastics results in increased abundance of [Polyvinyl Chloride co-treated with Polyethylene]] co-treated with [lead acetate results in increased abundance of Lead]] results in decreased expression of HMOX1 protein; [Microplastics results in increased abundance of [Polyvinyl Chloride co-treated with Polyethylene]] promotes the reaction [[lead acetate results in increased abundance of Lead] which results in decreased expression of HMOX1 mRNA]; [Microplastics results in increased abundance of [Polyvinyl Chloride co-treated with Polyethylene]] promotes the reaction [[lead acetate results in increased abundance of Lead] which results in decreased expression of HMOX1 protein] CTD PMID:38180308 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO Polyethylene analog promotes the reaction [Lipopolysaccharides results in increased secretion of IL1B protein] CTD PMID:10602080 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il6 interleukin 6 increases expression
multiple interactions		 ISO Polyethylene results in increased expression of IL6 mRNA; Polyethylene results in increased expression of IL6 protein
[[Microplastics results in increased abundance of [Polyvinyl Chloride co-treated with Polyethylene]] co-treated with [lead acetate results in increased abundance of Lead]] results in increased expression of IL6 protein; Polyethylene analog inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]		 CTD PMID:10602080 PMID:11771709 PMID:38180308 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Keap1 Kelch-like ECH-associated protein 1 multiple interactions ISO [[Microplastics results in increased abundance of [Polyvinyl Chloride co-treated with Polyethylene]] co-treated with [lead acetate results in increased abundance of Lead]] results in increased expression of KEAP1 mRNA; [[Microplastics results in increased abundance of [Polyvinyl Chloride co-treated with Polyethylene]] co-treated with [lead acetate results in increased abundance of Lead]] results in increased expression of KEAP1 protein; [Microplastics results in increased abundance of [Polyvinyl Chloride co-treated with Polyethylene]] promotes the reaction [[lead acetate results in increased abundance of Lead] which results in increased expression of KEAP1 mRNA]; [Microplastics results in increased abundance of [Polyvinyl Chloride co-treated with Polyethylene]] promotes the reaction [[lead acetate results in increased abundance of Lead] which results in increased expression of KEAP1 protein] CTD PMID:38180308 NCBI chr 8:19,768,375...19,777,862
Ensembl chr 8:19,768,375...19,777,862 		JBrowse link
G Litaf lipopolysaccharide-induced TNF factor increases expression ISO Polyethylene results in increased expression of LITAF mRNA CTD PMID:17408380 NCBI chr10:4,656,308...4,692,981
Ensembl chr10:4,625,552...4,692,763 		JBrowse link
G Neurod1 neuronal differentiation 1 decreases expression ISO Polyethylene results in decreased expression of NEUROD1 mRNA CTD PMID:23203475 NCBI chr 3:64,359,554...64,363,526
Ensembl chr 3:64,359,395...64,363,649 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 multiple interactions ISO [[Microplastics results in increased abundance of [Polyvinyl Chloride co-treated with Polyethylene]] co-treated with [lead acetate results in increased abundance of Lead]] results in decreased expression of NFE2L2 protein; [[Microplastics results in increased abundance of [Polyvinyl Chloride co-treated with Polyethylene]] co-treated with [lead acetate results in increased abundance of Lead]] results in increased expression of NFE2L2 mRNA; [Microplastics results in increased abundance of [Polyvinyl Chloride co-treated with Polyethylene]] promotes the reaction [[lead acetate results in increased abundance of Lead] which results in increased expression of NFE2L2 mRNA] CTD PMID:38180308 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737 		JBrowse link
G Notch1 notch receptor 1 decreases expression ISO Polyethylene results in decreased expression of NOTCH1 mRNA CTD PMID:23203475 NCBI chr 3:9,277,955...9,323,531
Ensembl chr 3:9,278,086...9,323,531 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO [[Microplastics results in increased abundance of [Polyvinyl Chloride co-treated with Polyethylene]] co-treated with [lead acetate results in increased abundance of Lead]] results in increased phosphorylation of RELA protein; [Microplastics results in increased abundance of [Polyvinyl Chloride co-treated with Polyethylene]] promotes the reaction [[lead acetate results in increased abundance of Lead] which results in increased phosphorylation of RELA protein] CTD PMID:38180308 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484 		JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase increases expression ISO Polyethylene results in increased expression of SRC mRNA CTD PMID:15585240 NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476 		JBrowse link
G Tnf tumor necrosis factor increases expression
multiple interactions
affects secretion		 ISO Polyethylene results in increased expression of TNF mRNA
[[Microplastics results in increased abundance of [Polyvinyl Chloride co-treated with Polyethylene]] co-treated with [lead acetate results in increased abundance of Lead]] results in increased expression of TNF protein; Polyethylene analog inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]
Polyethylene affects the secretion of TNF protein
Etidronic Acid inhibits the reaction [Polyethylene affects the secretion of TNF protein]; ibandronic acid inhibits the reaction [Polyethylene affects the secretion of TNF protein]		 CTD PMID:10413987 PMID:10602080 PMID:17408380 PMID:38180308 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tnfrsf11b TNF receptor superfamily member 11B decreases expression
decreases secretion		 ISO Polyethylene results in decreased expression of TNFRSF11B protein
Polyethylene results in decreased secretion of TNFRSF11B protein		 CTD PMID:15046894 PMID:15585240 NCBI chr 7:85,566,520...85,594,526
Ensembl chr 7:85,566,520...85,594,538 		JBrowse link
G Tnfsf11 TNF superfamily member 11 affects secretion
increases secretion		 ISO Polyethylene affects the secretion of TNFSF11 protein
Polyethylene results in increased secretion of TNFSF11 protein		 CTD PMID:15046894 PMID:15585240 NCBI chr15:53,673,850...53,705,325
Ensembl chr15:53,673,877...53,705,445 		JBrowse link
poly(styrene) term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C3 complement C3 increases expression ISO styrofoam analog results in increased expression of C3 protein CTD PMID:19428933 NCBI chr 9:2,087,437...2,114,366
Ensembl chr 9:2,087,437...2,114,429 		JBrowse link
G C5 complement C5 increases expression ISO styrofoam analog results in increased expression of C5 protein CTD PMID:19428933 NCBI chr 3:18,270,696...18,361,994
Ensembl chr 3:18,270,696...18,361,994 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions
affects activity		 ISO styrofoam analog promotes the reaction [Cimetidine results in decreased activity of CYP1A2 protein]
styrofoam analog affects the activity of CYP1A2 protein		 CTD PMID:19909766 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312 		JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 decreases activity
multiple interactions		 ISO styrofoam analog results in decreased activity of CYP2D6 protein
styrofoam analog promotes the reaction [Cimetidine results in decreased activity of CYP2D6 protein]		 CTD PMID:19909766 NCBI chr 7:113,882,584...113,891,754
Ensembl chr 7:113,881,618...113,891,759 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 decreases activity
multiple interactions		 ISO styrofoam analog results in decreased activity of CYP3A4 protein
styrofoam analog promotes the reaction [Cimetidine results in decreased activity of CYP3A4 protein]		 CTD PMID:19909766 NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008 		JBrowse link
G Itgam integrin subunit alpha M increases expression ISO styrofoam analog results in increased expression of ITGAM protein CTD PMID:19428933 NCBI chr 1:182,659,047...182,709,501
Ensembl chr 1:182,659,000...182,709,503 		JBrowse link
G Pf4 platelet factor 4 increases secretion ISO styrofoam analog results in increased secretion of PF4 protein CTD PMID:19428933 NCBI chr14:17,298,304...17,299,220
Ensembl chr14:17,298,308...17,299,365 		JBrowse link
G Ppbp pro-platelet basic protein increases secretion ISO styrofoam analog results in increased secretion of PPBP protein CTD PMID:19428933 NCBI chr14:17,302,326...17,303,130
Ensembl chr14:17,302,326...17,303,130 		JBrowse link
G Selp selectin P increases expression ISO styrofoam results in increased expression of SELP protein CTD PMID:21123846 NCBI chr13:76,476,229...76,511,846
Ensembl chr13:76,476,295...76,511,845 		JBrowse link
poly(vinyl chloride) term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Angpt1 angiopoietin 1 decreases expression ISO Polyvinyl Chloride results in decreased expression of ANGPT1 mRNA CTD PMID:12809767 NCBI chr 7:73,528,345...73,783,953
Ensembl chr 7:73,531,486...73,784,067 		JBrowse link
G Cat catalase multiple interactions ISO [[Microplastics results in increased abundance of [Polyvinyl Chloride co-treated with Polyethylene]] co-treated with [lead acetate results in increased abundance of Lead]] results in decreased expression of CAT protein; [lead acetate results in increased abundance of Lead] promotes the reaction [[Microplastics results in increased abundance of [Polyvinyl Chloride co-treated with Polyethylene]] which results in decreased expression of CAT protein]; [Microplastics results in increased abundance of [Polyvinyl Chloride co-treated with Polyethylene]] promotes the reaction [[lead acetate results in increased abundance of Lead] which results in decreased expression of CAT protein]; [Microplastics results in increased abundance of [Polyvinyl Chloride co-treated with Polyethylene]] which results in decreased expression of CAT protein CTD PMID:38180308 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions ISO [[Microplastics results in increased abundance of [Polyvinyl Chloride co-treated with Polyethylene]] co-treated with [lead acetate results in increased abundance of Lead]] results in increased expression of GPT protein CTD PMID:38180308 NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494 		JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions ISO [[Microplastics results in increased abundance of [Polyvinyl Chloride co-treated with Polyethylene]] co-treated with [lead acetate results in increased abundance of Lead]] results in decreased expression of HMOX1 mRNA; [[Microplastics results in increased abundance of [Polyvinyl Chloride co-treated with Polyethylene]] co-treated with [lead acetate results in increased abundance of Lead]] results in decreased expression of HMOX1 protein; [Microplastics results in increased abundance of [Polyvinyl Chloride co-treated with Polyethylene]] promotes the reaction [[lead acetate results in increased abundance of Lead] which results in decreased expression of HMOX1 mRNA]; [Microplastics results in increased abundance of [Polyvinyl Chloride co-treated with Polyethylene]] promotes the reaction [[lead acetate results in increased abundance of Lead] which results in decreased expression of HMOX1 protein] CTD PMID:38180308 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Il6 interleukin 6 multiple interactions ISO [[Microplastics results in increased abundance of [Polyvinyl Chloride co-treated with Polyethylene]] co-treated with [lead acetate results in increased abundance of Lead]] results in increased expression of IL6 protein CTD PMID:38180308 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Keap1 Kelch-like ECH-associated protein 1 multiple interactions ISO [[Microplastics results in increased abundance of [Polyvinyl Chloride co-treated with Polyethylene]] co-treated with [lead acetate results in increased abundance of Lead]] results in increased expression of KEAP1 mRNA; [[Microplastics results in increased abundance of [Polyvinyl Chloride co-treated with Polyethylene]] co-treated with [lead acetate results in increased abundance of Lead]] results in increased expression of KEAP1 protein; [Microplastics results in increased abundance of [Polyvinyl Chloride co-treated with Polyethylene]] promotes the reaction [[lead acetate results in increased abundance of Lead] which results in increased expression of KEAP1 mRNA]; [Microplastics results in increased abundance of [Polyvinyl Chloride co-treated with Polyethylene]] promotes the reaction [[lead acetate results in increased abundance of Lead] which results in increased expression of KEAP1 protein] CTD PMID:38180308 NCBI chr 8:19,768,375...19,777,862
Ensembl chr 8:19,768,375...19,777,862 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 multiple interactions ISO [[Microplastics results in increased abundance of [Polyvinyl Chloride co-treated with Polyethylene]] co-treated with [lead acetate results in increased abundance of Lead]] results in decreased expression of NFE2L2 protein; [[Microplastics results in increased abundance of [Polyvinyl Chloride co-treated with Polyethylene]] co-treated with [lead acetate results in increased abundance of Lead]] results in increased expression of NFE2L2 mRNA; [Microplastics results in increased abundance of [Polyvinyl Chloride co-treated with Polyethylene]] promotes the reaction [[lead acetate results in increased abundance of Lead] which results in increased expression of NFE2L2 mRNA] CTD PMID:38180308 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO [[Microplastics results in increased abundance of [Polyvinyl Chloride co-treated with Polyethylene]] co-treated with [lead acetate results in increased abundance of Lead]] results in increased phosphorylation of RELA protein; [Microplastics results in increased abundance of [Polyvinyl Chloride co-treated with Polyethylene]] promotes the reaction [[lead acetate results in increased abundance of Lead] which results in increased phosphorylation of RELA protein] CTD PMID:38180308 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484 		JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO [[Microplastics results in increased abundance of [Polyvinyl Chloride co-treated with Polyethylene]] co-treated with [lead acetate results in increased abundance of Lead]] results in increased expression of TNF protein CTD PMID:38180308 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
poly(vinylpyrrolidone) term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G App amyloid beta precursor protein multiple interactions ISO [Silver Compounds co-treated with Povidone] results in increased expression of APP protein CTD PMID:35697184 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561 		JBrowse link
G Atp5mc2 ATP synthase membrane subunit c locus 2 multiple interactions EXP [Silver analog co-treated with Povidone] results in decreased expression of ATP5MC2 mRNA CTD PMID:25194297 NCBI chr 7:133,791,341...133,799,713
Ensembl chr 7:133,791,342...133,799,733 		JBrowse link
G Bola3 bolA family member 3 multiple interactions EXP [Silver analog co-treated with Povidone] results in decreased expression of BOLA3 mRNA CTD PMID:25194297 NCBI chr 4:115,853,350...115,862,797
Ensembl chr 4:115,853,350...115,862,797 		JBrowse link
G Casp3 caspase 3 multiple interactions ISO [Silver co-treated with Povidone] affects the expression of CASP3 protein; [Silver co-treated with Povidone] results in decreased expression of CASP3 mRNA CTD PMID:27387714 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions ISO [Silver co-treated with Povidone] results in decreased expression of CDKN1A mRNA; [Silver co-treated with Povidone] results in decreased expression of CDKN1A protein CTD PMID:27387714 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585 		JBrowse link
G Col8a1 collagen type VIII alpha 1 chain multiple interactions EXP [Silver analog co-treated with Povidone] results in increased expression of COL8A1 mRNA CTD PMID:25194297 NCBI chr11:42,776,851...42,906,432
Ensembl chr11:42,777,628...42,906,424 		JBrowse link
G Cox17 cytochrome c oxidase copper chaperone COX17 multiple interactions EXP [Silver analog co-treated with Povidone] results in decreased expression of COX17 mRNA CTD PMID:25194297 NCBI chr11:62,400,733...62,406,507 JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions EXP [Silver analog co-treated with Povidone] results in increased expression of CYP1A1 mRNA CTD PMID:25194297 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125 		JBrowse link
G Dad1 defender against cell death 1 multiple interactions EXP [Silver analog co-treated with Povidone] results in decreased expression of DAD1 mRNA CTD PMID:25194297 NCBI chr15:27,677,286...27,697,120
Ensembl chr15:27,677,268...27,697,347 		JBrowse link
G Dlg4 discs large MAGUK scaffold protein 4 multiple interactions ISO [Silver Compounds co-treated with Povidone] results in decreased expression of DLG4 protein CTD PMID:35697184 NCBI chr10:54,740,700...54,769,097
Ensembl chr10:54,739,470...54,767,153 		JBrowse link
G Gbp2 guanylate binding protein 2 multiple interactions EXP [Silver analog co-treated with Povidone] results in decreased expression of GBP2 mRNA CTD PMID:25194297 NCBI chr 2:231,332,488...231,348,573
Ensembl chr 2:231,332,284...231,348,571 		JBrowse link
G H2ax H2A.X variant histone multiple interactions ISO [Silver co-treated with Povidone] results in increased expression of H2AX protein modified form CTD PMID:27387714 NCBI chr 8:44,671,907...44,673,262
Ensembl chr 8:44,671,786...44,673,239
Ensembl chr 4:44,671,786...44,673,239 		JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions EXP [Silver analog co-treated with Povidone] results in increased expression of HMOX1 mRNA CTD PMID:25194297 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Ifit3 interferon-induced protein with tetratricopeptide repeats 3 multiple interactions EXP [Silver analog co-treated with Povidone] results in decreased expression of IFIT3 mRNA CTD PMID:25194297 NCBI chr 1:232,114,166...232,119,311
Ensembl chr 1:232,114,166...232,119,307 		JBrowse link
G Lims1 LIM zinc finger domain containing 1 multiple interactions EXP [Silver analog co-treated with Povidone] results in increased expression of LIMS1 mRNA CTD PMID:25194297 NCBI chr20:26,309,833...26,418,511
Ensembl chr20:26,309,895...26,418,500 		JBrowse link
G Lmnb2 lamin B2 multiple interactions EXP [Silver analog co-treated with Povidone] results in decreased expression of LMNB2 mRNA CTD PMID:25194297 NCBI chr 7:8,792,628...8,808,665
Ensembl chr 7:8,789,314...8,808,665 		JBrowse link
G Map2 microtubule-associated protein 2 multiple interactions ISO [Silver Compounds co-treated with Povidone] results in decreased expression of MAP2 protein CTD PMID:35697184 NCBI chr 9:67,723,422...67,981,886
Ensembl chr 9:67,723,371...67,979,809 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO [Silver Compounds co-treated with Povidone] results in increased activity of MAPK1 protein CTD PMID:21729742 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO [Silver Compounds co-treated with Povidone] results in increased activity of MAPK3 protein CTD PMID:21729742 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Mdm2 MDM2 proto-oncogene multiple interactions ISO [Silver co-treated with Povidone] affects the expression of MDM2 protein; [Silver co-treated with Povidone] results in decreased expression of MDM2 mRNA CTD PMID:27387714 NCBI chr 7:53,290,660...53,315,205
Ensembl chr 7:53,290,664...53,314,915 		JBrowse link
G Mt1 metallothionein 1 multiple interactions EXP [Silver analog co-treated with Povidone] affects the expression of MT1A mRNA CTD PMID:25194297 NCBI chr19:10,826,032...10,827,048
Ensembl chr19:10,826,032...10,827,049
Ensembl chr17:10,826,032...10,827,049
Ensembl chr  X:10,826,032...10,827,049 		JBrowse link
G Nfix nuclear factor I X multiple interactions EXP [Silver analog co-treated with Povidone] results in increased expression of NFIX mRNA CTD PMID:25194297 NCBI chr19:23,355,388...23,450,360
Ensembl chr19:23,355,498...23,448,265 		JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 multiple interactions EXP [Silver analog co-treated with Povidone] results in increased expression of NQO1 mRNA CTD PMID:25194297 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557 		JBrowse link
G Nrm nurim multiple interactions EXP [Silver analog co-treated with Povidone] results in decreased expression of NRM mRNA CTD PMID:25194297 NCBI chr20:2,888,321...2,892,804
Ensembl chr20:2,877,567...2,891,802 		JBrowse link
G Nuak2 NUAK family kinase 2 multiple interactions EXP [Silver analog co-treated with Povidone] results in decreased expression of NUAK2 mRNA CTD PMID:25194297 NCBI chr13:43,753,454...43,770,604
Ensembl chr13:43,753,832...43,770,604 		JBrowse link
G Ocln occludin affects expression ISO Povidone affects the expression of OCLN mRNA CTD PMID:19729060 NCBI chr 2:31,657,217...31,707,466
Ensembl chr 2:31,657,220...31,764,150 		JBrowse link
G Pink1 PTEN induced kinase 1 multiple interactions ISO [Silver Compounds co-treated with Povidone] results in increased expression of PINK1 protein CTD PMID:35697184 NCBI chr 5:150,530,523...150,542,635
Ensembl chr 5:150,530,523...150,542,635 		JBrowse link
G Ppargc1a PPARG coactivator 1 alpha multiple interactions ISO [Silver Compounds co-treated with Povidone] results in decreased expression of PPARGC1A protein CTD PMID:35697184 NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656 		JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase multiple interactions ISO [Silver Compounds co-treated with Povidone] results in increased expression of PRKN protein CTD PMID:35697184 NCBI chr 1:48,688,651...49,882,520
Ensembl chr 1:48,690,556...49,882,555 		JBrowse link
G Prpf38b pre-mRNA processing factor 38B multiple interactions EXP [Silver analog co-treated with Povidone] results in decreased expression of PRPF38B mRNA CTD PMID:25194297 NCBI chr 2:196,553,224...196,562,271
Ensembl chr 2:196,553,225...196,562,250 		JBrowse link
G Prr13 proline rich 13 multiple interactions EXP [Silver analog co-treated with Povidone] results in decreased expression of PRR13 mRNA CTD PMID:25194297 NCBI chr 7:133,592,511...133,595,817
Ensembl chr 7:133,592,490...133,601,005 		JBrowse link
G Psenen presenilin enhancer gamma secretase subunit multiple interactions EXP [Silver analog co-treated with Povidone] results in decreased expression of PSENEN mRNA CTD PMID:25194297 NCBI chr 1:85,814,905...85,816,654
Ensembl chr 1:85,814,905...85,816,192 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions EXP [Silver analog co-treated with Povidone] results in increased expression of PTGS2 mRNA CTD PMID:25194297 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Ptk2 protein tyrosine kinase 2 multiple interactions ISO [Silver Compounds co-treated with Povidone] results in increased activity of PTK2 protein CTD PMID:21729742 NCBI chr 7:105,126,725...105,331,848
Ensembl chr 7:105,126,728...105,331,783 		JBrowse link
G Rab14 RAB14, member RAS oncogene family multiple interactions EXP [Silver analog co-treated with Povidone] results in increased expression of RAB14 mRNA CTD PMID:25194297 NCBI chr 3:18,501,953...18,523,253
Ensembl chr 3:18,501,963...18,523,172 		JBrowse link
G Rbm25l1 RNA binding motif protein 25-like 1 multiple interactions EXP [Silver analog co-treated with Povidone] results in increased expression of RBM25L1 mRNA CTD PMID:25194297 NCBI chr10:10,267,026...10,270,510
Ensembl chr10:10,267,260...10,269,710
Ensembl chr 6:10,267,260...10,269,710 		JBrowse link
G Samd9l sterile alpha motif domain containing 9 like multiple interactions EXP [Silver analog co-treated with Povidone] results in decreased expression of SAMD9L mRNA CTD PMID:25194297 NCBI chr 4:31,362,054...31,376,412
Ensembl chr 4:31,361,669...31,376,415 		JBrowse link
G Selenow selenoprotein W multiple interactions EXP [Silver analog co-treated with Povidone] results in decreased expression of SELENOW mRNA CTD PMID:25194297 NCBI chr 1:76,599,441...76,604,514
Ensembl chr 1:76,598,779...76,604,724
Ensembl chr 1:76,598,779...76,604,724 		JBrowse link
G Slc5a3 solute carrier family 5 member 3 multiple interactions EXP [Silver analog co-treated with Povidone] results in increased expression of SLC5A3 mRNA CTD PMID:25194297 NCBI chr11:31,313,847...31,316,293
Ensembl chr11:31,295,476...31,318,883 		JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions ISO [Silver co-treated with Povidone] results in increased expression of SOD2 mRNA; [Silver co-treated with Povidone] results in increased expression of SOD2 protein CTD PMID:27387714 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189 		JBrowse link
G Sparc secreted protein acidic and cysteine rich multiple interactions EXP [Silver analog co-treated with Povidone] results in decreased expression of SPARC mRNA CTD PMID:25194297 NCBI chr10:39,516,394...39,538,252
Ensembl chr10:39,516,406...39,538,396 		JBrowse link
G Stat2 signal transducer and activator of transcription 2 multiple interactions EXP [Silver analog co-treated with Povidone] results in decreased expression of STAT2 mRNA CTD PMID:25194297 NCBI chr 7:702,565...718,349
Ensembl chr 7:702,495...718,967 		JBrowse link
G Sv2b synaptic vesicle glycoprotein 2b multiple interactions EXP [Silver analog co-treated with Povidone] results in increased expression of SV2B mRNA CTD PMID:25194297 NCBI chr 1:128,978,471...129,152,479
Ensembl chr 1:128,978,473...129,152,479 		JBrowse link
G Syp synaptophysin multiple interactions ISO [Silver Compounds co-treated with Povidone] results in increased expression of SYP protein CTD PMID:35697184 NCBI chr  X:14,849,444...14,864,553
Ensembl chr  X:14,849,444...14,864,745 		JBrowse link
G Tiparp TCDD-inducible poly(ADP-ribose) polymerase multiple interactions EXP [Silver analog co-treated with Povidone] results in increased expression of TIPARP mRNA CTD PMID:25194297 NCBI chr 2:149,753,682...149,780,327
Ensembl chr 2:149,753,682...149,780,327 		JBrowse link
G Tmtc3 transmembrane O-mannosyltransferase targeting cadherins 3 multiple interactions EXP [Silver analog co-treated with Povidone] results in increased expression of TMTC3 mRNA CTD PMID:25194297 NCBI chr 7:35,264,886...35,310,010
Ensembl chr 7:35,264,892...35,310,385 		JBrowse link
G Tp53 tumor protein p53 multiple interactions ISO [Silver co-treated with Povidone] affects the phosphorylation of TP53 protein; [Silver co-treated with Povidone] results in decreased expression of TP53 mRNA; [Silver co-treated with Povidone] results in decreased expression of TP53 protein CTD PMID:27387714 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
G Trappc1 trafficking protein particle complex subunit 1 multiple interactions EXP [Silver analog co-treated with Povidone] results in decreased expression of TRAPPC1 mRNA CTD PMID:25194297 NCBI chr10:54,045,598...54,047,184
Ensembl chr10:54,045,537...54,047,331 		JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions ISO [Silver Compounds co-treated with Povidone] results in increased expression of VEGFA protein CTD PMID:21729742 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641 		JBrowse link
G Wdfy1 WD repeat and FYVE domain containing 1 multiple interactions EXP [Silver analog co-treated with Povidone] results in increased expression of WDFY1 mRNA CTD PMID:25194297 NCBI chr 9:81,034,852...81,092,823
Ensembl chr 9:81,034,849...81,092,775 		JBrowse link
G Zfhx3 zinc finger homeobox 3 multiple interactions EXP [Silver analog co-treated with Povidone] results in increased expression of ZFHX3 mRNA CTD PMID:25194297 NCBI chr19:36,257,196...36,886,104
Ensembl chr19:36,630,254...36,881,771 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19874
    chemical entity 19872
      molecular entity 19872
        polyatomic entity 19824
          macromolecule 8832
            homopolymer macromolecule 116
              poly(alkylene) macromolecule 86
                poly(alkylene) polymer + 0
                poly(isobutylene) 0
                poly(methylene) 0
                polyethylene macromolecule + 86
Path 2
Term Annotations click to browse term
  CHEBI ontology 19874
    subatomic particle 19872
      composite particle 19872
        hadron 19872
          baryon 19872
            nucleon 19872
              atomic nucleus 19872
                atom 19872
                  group 19825
                    polyatomic entity 19824
                      macromolecule 8832
                        homopolymer macromolecule 116
                          poly(alkylene) macromolecule 86
                            poly(alkylene) polymer + 0
                            poly(isobutylene) 0
                            poly(methylene) 0
                            polyethylene macromolecule + 86
paths to the root