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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:2,4-dinitrobenzenesulfonic acid
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Accession:CHEBI:53070 term browser browse the term
Definition:The arenesulfonic acid that is benzenesulfonic acid with two nitro substituents in the 2- and 4-positions.
Synonyms:related_synonym: 2,4-DNBSA;   2,4-Dinitrobenzenesulphonic acid;   2,4-dinitrobenzene sulfonic acid;   2,4-dinitrobenzene sulphonic acid;   2,4-dinitrobenzene-1-sulfonic acid;   2,4-dinitrobenzene-1-sulphonic acid;   DNBA;   DNBS;   DNBSA;   Formula=C6H4N2O7S;   InChI=1S/C6H4N2O7S/c9-7(10)4-1-2-6(16(13,14)15)5(3-4)8(11)12/h1-3H,(H,13,14,15);   InChIKey=OVOJUAKDTOOXRF-UHFFFAOYSA-N;   SMILES=OS(=O)(=O)c1ccc(cc1[N+]([O-])=O)[N+]([O-])=O;   dinitrobenzenesulfonic acid
 xref: CAS:89-02-1;   Gmelin:5198
 xref_mesh: MESH:C001073
 xref: PMID:11739495;   PMID:15307184;   PMID:20336084;   PMID:20631061;   PMID:21354356;   PMID:21915296;   PMID:22144769;   PMID:23494123;   PMID:23554310;   PMID:7994925;   PMID:8466279;   Reaxys:2147447
 cyclic_relationship: is_conjugate_acid_of CHEBI:53069


show annotations for term's descendants           Sort by:
2,4-dinitrobenzenesulfonic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ada adenosine deaminase increases expression EXP 2,4-dinitrobenzenesulfonic acid results in increased expression of ADA mRNA CTD PMID:20860664 NCBI chr 3:152,398,745...152,422,854
Ensembl chr 3:152,398,747...152,447,088 		JBrowse link
G Adarb1 adenosine deaminase, RNA-specific, B1 increases expression ISO 2,4-dinitrobenzenesulfonic acid results in increased expression of ADARB1 mRNA CTD PMID:30116771 NCBI chr20:11,222,569...11,350,854
Ensembl chr20:11,222,583...11,350,852 		JBrowse link
G Adora3 adenosine A3 receptor increases expression EXP 2,4-dinitrobenzenesulfonic acid results in increased expression of ADORA3 mRNA; 2,4-dinitrobenzenesulfonic acid results in increased expression of ADORA3 protein CTD PMID:20860664 NCBI chr 2:193,352,759...193,392,946
Ensembl chr 2:193,388,713...193,392,357 		JBrowse link
G Atf3 activating transcription factor 3 increases expression ISO 2,4-dinitrobenzenesulfonic acid results in increased expression of ATF3 mRNA CTD PMID:30116771 NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631 		JBrowse link
G Bnip3 BCL2 interacting protein 3 decreases expression ISO 2,4-dinitrobenzenesulfonic acid results in decreased expression of BNIP3 mRNA CTD PMID:30116771 NCBI chr 1:193,708,164...193,725,348
Ensembl chr 1:193,708,167...193,725,359 		JBrowse link
G Caly calcyon neuron-specific vesicular protein decreases expression ISO 2,4-dinitrobenzenesulfonic acid results in decreased expression of CALY mRNA CTD PMID:30116771 NCBI chr 1:194,862,671...194,873,861
Ensembl chr 1:194,862,672...194,873,551 		JBrowse link
G Ccl7 C-C motif chemokine ligand 7 increases expression ISO 2,4-dinitrobenzenesulfonic acid results in increased expression of CCL7 mRNA CTD PMID:30116771 NCBI chr10:67,016,446...67,018,296
Ensembl chr10:67,016,446...67,018,303 		JBrowse link
G Ccr2 C-C motif chemokine receptor 2 increases expression ISO 2,4-dinitrobenzenesulfonic acid results in increased expression of CCR2 mRNA CTD PMID:30116771 NCBI chr 8:123,734,465...123,742,483
Ensembl chr 8:123,734,430...123,742,100 		JBrowse link
G Cdh4 cadherin 4 decreases expression ISO 2,4-dinitrobenzenesulfonic acid results in decreased expression of CDH4 mRNA CTD PMID:30116771 NCBI chr 3:166,525,092...167,003,380
Ensembl chr 3:166,525,099...167,003,371 		JBrowse link
G Ciapin1 cytokine induced apoptosis inhibitor 1 increases expression ISO 2,4-dinitrobenzenesulfonic acid results in increased expression of CIAPIN1 mRNA CTD PMID:30116771 NCBI chr19:10,179,963...10,195,511
Ensembl chr19:10,180,100...10,195,503 		JBrowse link
G Cnr1 cannabinoid receptor 1 decreases response to substance ISO CNR1 results in decreased susceptibility to 2,4-dinitrobenzenesulfonic acid CTD PMID:15085199 NCBI chr 5:48,408,543...48,436,099
Ensembl chr 5:48,408,574...48,435,099 		JBrowse link
G Creb1 cAMP responsive element binding protein 1 affects expression ISO 2,4-dinitrobenzenesulfonic acid affects the expression of CREB1 mRNA CTD PMID:20385217 NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816 		JBrowse link
G Crlf1 cytokine receptor-like factor 1 increases expression ISO 2,4-dinitrobenzenesulfonic acid results in increased expression of CRLF1 mRNA CTD PMID:30116771 NCBI chr16:18,924,722...18,936,049
Ensembl chr16:18,924,722...18,935,997 		JBrowse link
G Ctnna3 catenin alpha 3 decreases expression ISO 2,4-dinitrobenzenesulfonic acid results in decreased expression of CTNNA3 mRNA CTD PMID:30116771 NCBI chr20:23,614,469...25,200,026
Ensembl chr20:23,623,560...25,199,978 		JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 increases expression ISO 2,4-dinitrobenzenesulfonic acid results in increased expression of CXCL1 mRNA CTD PMID:30116771 NCBI chr14:17,287,727...17,289,451
Ensembl chr14:17,270,146...17,289,511 		JBrowse link
G Dlc1 DLC1 Rho GTPase activating protein multiple interactions
decreases expression		 ISO [2,4-dinitrobenzenesulfonic acid co-treated with GR 159897] results in increased expression of DLC1 mRNA
2,4-dinitrobenzenesulfonic acid results in decreased expression of DLC1 mRNA		 CTD PMID:30116771 NCBI chr16:55,246,716...55,671,441
Ensembl chr16:55,291,584...55,671,439 		JBrowse link
G Faah fatty acid amide hydrolase increases response to substance ISO FAAH results in increased susceptibility to 2,4-dinitrobenzenesulfonic acid CTD PMID:15085199 NCBI chr 5:129,479,774...129,499,018
Ensembl chr 5:129,479,824...129,498,677 		JBrowse link
G Fat4 FAT atypical cadherin 4 decreases expression ISO 2,4-dinitrobenzenesulfonic acid results in decreased expression of FAT4 mRNA CTD PMID:30116771 NCBI chr 2:121,927,266...122,056,700
Ensembl chr 2:121,927,942...122,056,707 		JBrowse link
G Fhl2 four and a half LIM domains 2 multiple interactions ISO [2,4-dinitrobenzenesulfonic acid co-treated with GR 159897] results in increased expression of FHL2 mRNA CTD PMID:30116771 NCBI chr 9:45,388,979...45,462,421
Ensembl chr 9:45,388,981...45,431,192 		JBrowse link
G Fhl3 four and a half LIM domains 3 increases expression ISO 2,4-dinitrobenzenesulfonic acid results in increased expression of FHL3 mRNA CTD PMID:30116771 NCBI chr 5:136,953,947...136,961,317
Ensembl chr 5:136,950,411...136,961,317 		JBrowse link
G Gcnt2 glucosaminyl (N-acetyl) transferase 2 increases expression ISO 2,4-dinitrobenzenesulfonic acid results in increased expression of GCNT2 mRNA CTD PMID:30116771 NCBI chr17:23,796,859...23,901,625
Ensembl chr17:23,796,859...23,901,611 		JBrowse link
G Gfap glial fibrillary acidic protein increases expression
multiple interactions		 ISO 2,4-dinitrobenzenesulfonic acid results in increased expression of GFAP mRNA
GR 159897 inhibits the reaction [2,4-dinitrobenzenesulfonic acid results in increased expression of GFAP mRNA]		 CTD PMID:30116771 NCBI chr10:87,852,891...87,861,631
Ensembl chr10:87,852,890...87,861,589 		JBrowse link
G Igf1r insulin-like growth factor 1 receptor decreases expression ISO 2,4-dinitrobenzenesulfonic acid results in decreased expression of IGF1R mRNA CTD PMID:30116771 NCBI chr 1:121,549,831...121,838,548
Ensembl chr 1:121,550,743...121,831,777 		JBrowse link
G Il10ra interleukin 10 receptor subunit alpha increases expression ISO 2,4-dinitrobenzenesulfonic acid results in increased expression of IL10RA mRNA CTD PMID:30116771 NCBI chr 8:45,563,009...45,578,041
Ensembl chr 8:45,563,137...45,578,061 		JBrowse link
G Il6 interleukin 6 increases expression ISO 2,4-dinitrobenzenesulfonic acid results in increased expression of IL6 mRNA CTD PMID:30116771 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Itpk1 inositol-tetrakisphosphate 1-kinase multiple interactions
decreases expression		 ISO [2,4-dinitrobenzenesulfonic acid co-treated with GR 159897] results in increased expression of ITPK1 mRNA
2,4-dinitrobenzenesulfonic acid results in decreased expression of ITPK1 mRNA		 CTD PMID:30116771 NCBI chr 6:121,710,750...121,844,501
Ensembl chr 6:121,710,755...121,844,107 		JBrowse link
G Jaml junction adhesion molecule like increases expression ISO 2,4-dinitrobenzenesulfonic acid results in increased expression of JAML mRNA CTD PMID:30116771 NCBI chr 8:45,384,836...45,415,459
Ensembl chr 8:45,383,495...45,416,565 		JBrowse link
G Kalrn kalirin, RhoGEF kinase increases expression
multiple interactions		 ISO 2,4-dinitrobenzenesulfonic acid results in increased expression of KALRN mRNA
[2,4-dinitrobenzenesulfonic acid co-treated with GR 159897] results in increased expression of KALRN mRNA		 CTD PMID:30116771 NCBI chr11:66,198,155...66,803,166
Ensembl chr11:66,198,173...66,797,610 		JBrowse link
G Kcnb2 potassium voltage-gated channel subfamily B member 2 multiple interactions
decreases expression		 ISO [2,4-dinitrobenzenesulfonic acid co-treated with GR 159897] results in increased expression of KCNB2 mRNA
2,4-dinitrobenzenesulfonic acid results in decreased expression of KCNB2 mRNA		 CTD PMID:30116771 NCBI chr 5:3,567,012...4,028,564
Ensembl chr 5:3,569,685...4,028,599 		JBrowse link
G Lif LIF, interleukin 6 family cytokine increases expression ISO 2,4-dinitrobenzenesulfonic acid results in increased expression of LIF mRNA CTD PMID:30116771 NCBI chr14:79,131,049...79,140,486
Ensembl chr14:79,134,574...79,140,482 		JBrowse link
G Mfsd6 major facilitator superfamily domain containing 6 decreases expression ISO 2,4-dinitrobenzenesulfonic acid results in decreased expression of MFSD6 mRNA CTD PMID:30116771 NCBI chr 9:48,773,171...48,858,471
Ensembl chr 9:48,773,414...48,858,465 		JBrowse link
G Msh2 mutS homolog 2 decreases expression ISO 2,4-dinitrobenzenesulfonic acid results in decreased expression of MSH2 mRNA CTD PMID:30116771 NCBI chr 6:6,813,793...6,872,960
Ensembl chr 6:6,813,795...6,872,938 		JBrowse link
G Nfix nuclear factor I X decreases expression ISO 2,4-dinitrobenzenesulfonic acid results in decreased expression of NFIX mRNA CTD PMID:30116771 NCBI chr19:23,355,388...23,450,360
Ensembl chr19:23,355,498...23,448,265 		JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 affects expression ISO 2,4-dinitrobenzenesulfonic acid affects the expression of NFKB1 mRNA CTD PMID:20385217 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404 		JBrowse link
G Nt5e 5' nucleotidase, ecto multiple interactions
decreases expression		 ISO [2,4-dinitrobenzenesulfonic acid co-treated with GR 159897] results in increased expression of NT5E mRNA
2,4-dinitrobenzenesulfonic acid results in decreased expression of NT5E mRNA		 CTD PMID:30116771 NCBI chr 8:89,271,046...89,314,918
Ensembl chr 8:89,270,696...89,314,881 		JBrowse link
G Odc1 ornithine decarboxylase 1 increases expression ISO 2,4-dinitrobenzenesulfonic acid results in increased expression of ODC1 mRNA CTD PMID:30116771 NCBI chr 6:40,329,831...40,336,444
Ensembl chr 6:40,329,964...40,336,440 		JBrowse link
G Oprk1 opioid receptor, kappa 1 decreases expression ISO 2,4-dinitrobenzenesulfonic acid results in decreased expression of OPRK1 mRNA CTD PMID:30116771 NCBI chr 5:13,860,016...13,877,823
Ensembl chr 5:13,860,021...13,877,823 		JBrowse link
G Pde4d phosphodiesterase 4D multiple interactions
decreases expression		 ISO [2,4-dinitrobenzenesulfonic acid co-treated with GR 159897] results in increased expression of PDE4D mRNA
2,4-dinitrobenzenesulfonic acid results in decreased expression of PDE4D mRNA		 CTD PMID:30116771 NCBI chr 2:40,014,933...41,529,190
Ensembl chr 2:40,019,933...41,525,884 		JBrowse link
G Pik3c2a phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha decreases expression ISO 2,4-dinitrobenzenesulfonic acid results in decreased expression of PIK3C2A mRNA CTD PMID:30116771 NCBI chr 1:170,577,942...170,684,353
Ensembl chr 1:170,577,942...170,683,472 		JBrowse link
G Psmb8 proteasome 20S subunit beta 8 decreases expression ISO 2,4-dinitrobenzenesulfonic acid results in decreased expression of PSMB8 mRNA CTD PMID:30116771 NCBI chr20:4,652,159...4,655,122
Ensembl chr20:4,652,159...4,655,283 		JBrowse link
G Ptger4 prostaglandin E receptor 4 decreases expression
multiple interactions		 ISO 2,4-dinitrobenzenesulfonic acid results in decreased expression of PTGER4 mRNA
[2,4-dinitrobenzenesulfonic acid co-treated with GR 159897] results in increased expression of PTGER4 mRNA		 CTD PMID:30116771 NCBI chr 2:54,330,563...54,347,451
Ensembl chr 2:54,335,424...54,346,670 		JBrowse link
G Rps15a ribosomal protein S15a increases expression ISO 2,4-dinitrobenzenesulfonic acid results in increased expression of RPS15A mRNA CTD PMID:30116771 NCBI chr 1:172,420,151...172,427,021
Ensembl chr 1:172,419,761...172,426,995 		JBrowse link
G RT1-A2 RT1 class Ia, locus A2 decreases expression ISO 2,4-dinitrobenzenesulfonic acid results in decreased expression of H2-T23 mRNA CTD PMID:30116771 NCBI chr20:4,870,939...4,910,183 JBrowse link
G RT1-Ba RT1 class II, locus Ba decreases expression ISO 2,4-dinitrobenzenesulfonic acid results in decreased expression of H2-AA mRNA CTD PMID:30116771 NCBI chr20:4,575,134...4,579,727
Ensembl chr20:4,575,134...4,579,744 		JBrowse link
G Sgcd sarcoglycan, delta decreases expression ISO 2,4-dinitrobenzenesulfonic acid results in decreased expression of SGCD mRNA CTD PMID:30116771 NCBI chr10:31,346,480...32,328,364
Ensembl chr10:31,280,511...31,724,840 		JBrowse link
G Slc9a1 solute carrier family 9 member A1 increases expression ISO 2,4-dinitrobenzenesulfonic acid results in increased expression of SLC9A1 mRNA CTD PMID:30116771 NCBI chr 5:145,576,341...145,629,630
Ensembl chr 5:145,576,334...145,629,624 		JBrowse link
G Tac1 tachykinin, precursor 1 multiple interactions
increases expression		 ISO GR 159897 inhibits the reaction [2,4-dinitrobenzenesulfonic acid results in increased expression of TAC1 mRNA] CTD PMID:30116771 NCBI chr 4:35,679,183...35,687,180
Ensembl chr 4:35,679,704...35,687,178 		JBrowse link
G Tacr2 tachykinin receptor 2 multiple interactions ISO [2,4-dinitrobenzenesulfonic acid co-treated with GR 159897] results in decreased expression of TACR2 mRNA CTD PMID:30116771 NCBI chr20:30,208,907...30,223,446
Ensembl chr20:30,208,907...30,223,446 		JBrowse link
G Taf1b TATA-box binding protein associated factor, RNA polymerase I subunit B multiple interactions
decreases expression		 ISO [2,4-dinitrobenzenesulfonic acid co-treated with GR 159897] results in increased expression of TAF1B mRNA
2,4-dinitrobenzenesulfonic acid results in decreased expression of TAF1B mRNA		 CTD PMID:30116771 NCBI chr 6:41,116,980...41,194,593
Ensembl chr 6:41,117,420...41,194,593 		JBrowse link
G Tapbpl TAP binding protein-like decreases expression ISO 2,4-dinitrobenzenesulfonic acid results in decreased expression of TAPBPL mRNA CTD PMID:30116771 NCBI chr 4:158,021,454...158,028,905 JBrowse link
G Thbs1 thrombospondin 1 increases expression ISO 2,4-dinitrobenzenesulfonic acid results in increased expression of THBS1 mRNA CTD PMID:30116771 NCBI chr 3:105,056,293...105,071,445
Ensembl chr 3:105,056,292...105,071,440 		JBrowse link
G Tnf tumor necrosis factor increases expression ISO 2,4-dinitrobenzenesulfonic acid results in increased expression of TNF mRNA CTD PMID:20385217 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Trim62 tripartite motif-containing 62 decreases expression ISO 2,4-dinitrobenzenesulfonic acid results in decreased expression of TRIM62 mRNA CTD PMID:30116771 NCBI chr 5:141,230,830...141,260,629
Ensembl chr 5:141,231,523...141,259,915 		JBrowse link
G Vti1a vesicle transport through interaction with t-SNAREs 1A increases expression
multiple interactions		 ISO 2,4-dinitrobenzenesulfonic acid results in increased expression of VTI1A mRNA
[2,4-dinitrobenzenesulfonic acid co-treated with GR 159897] results in increased expression of VTI1A mRNA		 CTD PMID:30116771 NCBI chr 1:254,356,343...254,661,854
Ensembl chr 1:254,356,429...254,661,852 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19874
    chemical entity 19872
      group 19825
        inorganic group 19404
          sulfo group 9951
            organosulfonic acid 9951
              arenesulfonic acid 687
                2,4-dinitrobenzenesulfonic acid 54
Path 2
Term Annotations click to browse term
  CHEBI ontology 19874
    subatomic particle 19872
      composite particle 19872
        hadron 19872
          baryon 19872
            nucleon 19872
              atomic nucleus 19872
                atom 19872
                  main group element atom 19811
                    p-block element atom 19811
                      chalcogen 19563
                        oxygen atom 19535
                          oxygen molecular entity 19535
                            hydroxides 19341
                              oxoacid 18777
                                chalcogen oxoacid 13781
                                  sulfur oxoacid 13570
                                    sulfonic acid 11616
                                      sulfo group 9951
                                        organosulfonic acid 9951
                                          arenesulfonic acid 687
                                            2,4-dinitrobenzenesulfonic acid 54
paths to the root