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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:2,4,6-trinitrobenzenesulfonic acid
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Accession:CHEBI:53063 term browser browse the term
Definition:The arenesulfonic acid that is benzenesulfonic acid with three nitro substituents in the 2-, 4- and 6-positions.
Synonyms:related_synonym: 2,4,6-Trinitrobenzene-1-sulfonic acid;   Formula=C6H3N3O9S;   InChI=1S/C6H3N3O9S/c10-7(11)3-1-4(8(12)13)6(19(16,17)18)5(2-3)9(14)15/h1-2H,(H,16,17,18);   InChIKey=NHJVRSWLHSJWIN-UHFFFAOYSA-N;   Picryl sulfonic acid;   SMILES=OS(=O)(=O)c1c(cc(cc1[N+]([O-])=O)[N+]([O-])=O)[N+]([O-])=O;   TNBS;   Trinitrobenzenesulfonic acid;   picrylsulfonic acid
 xref: CAS:2508-19-2;   Gmelin:1051138
 xref_mesh: MESH:D014302
 xref: PMID:10771133;   PMID:11033063;   PMID:12631250;   PMID:16675348;   PMID:17979222;   PMID:23246254;   PMID:23275612;   PMID:23307099;   PMID:23353033;   PMID:23434856;   PMID:23537331;   PMID:23558009;   PMID:23658667;   PMID:7843258;   PMID:7994925;   PMID:9326394;   PMID:9540973;   Reaxys:572358;   Wikipedia:2\,4\,6-Trinitrobenzenesulfonic_acid


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2,4,6-trinitrobenzenesulfonic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb11 ATP binding cassette subfamily B member 11 decreases expression EXP Trinitrobenzenesulfonic Acid results in decreased expression of ABCB11 mRNA; Trinitrobenzenesulfonic Acid results in decreased expression of ABCB11 protein CTD PMID:12044520 NCBI chr 3:54,016,854...54,112,797
Ensembl chr 3:54,017,127...54,112,730 		JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A decreases expression
multiple interactions		 ISO Trinitrobenzenesulfonic Acid results in decreased expression of ABCB1 mRNA
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of ABCB1 mRNA]		 CTD PMID:18200517 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709 		JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 decreases expression EXP Trinitrobenzenesulfonic Acid results in decreased expression of ABCC2 mRNA; Trinitrobenzenesulfonic Acid results in decreased expression of ABCC2 protein CTD PMID:12044520 NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238 		JBrowse link
G Actb actin, beta increases expression
decreases expression		 ISO
EXP		 Trinitrobenzenesulfonic Acid results in increased expression of ACTB mRNA
Trinitrobenzenesulfonic Acid results in decreased expression of ACTB mRNA		 CTD PMID:12163651 PMID:17982090 NCBI chr12:11,663,112...11,666,697
Ensembl chr12:11,663,109...11,672,877 		JBrowse link
G Adm2 adrenomedullin 2 increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of ADM2 mRNA CTD PMID:21808981 NCBI chr 7:120,393,179...120,394,965
Ensembl chr 7:120,393,179...120,396,331 		JBrowse link
G Ager advanced glycosylation end product-specific receptor multiple interactions
increases expression
increases abundance		 EXP cinnamaldehyde inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of AGER protein]; dapagliflozin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of AGER protein]; hesperetin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of AGER protein]; Mesalamine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of AGER protein]
2,4,6-trinitrobenzenesulfonic acid increases abundance of Ager protein in rat colon		 CTD
RGD		 PMID:33412153 PMID:33522063 PMID:29572553 RGD:152995414 NCBI chr20:4,148,150...4,151,361
Ensembl chr20:4,147,890...4,151,078 		JBrowse link
G Agr2 anterior gradient 2, protein disulphide isomerase family member increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of AGR2 mRNA CTD PMID:17982090 NCBI chr 6:52,708,602...52,729,378
Ensembl chr 6:52,708,602...52,729,371 		JBrowse link
G Ahr aryl hydrocarbon receptor multiple interactions ISO [Tetrachlorodibenzodioxin results in increased activity of AHR protein] which results in decreased susceptibility to Trinitrobenzenesulfonic Acid CTD PMID:21131560 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568 		JBrowse link
G Ak3 adenylate kinase 3 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of AK3 mRNA CTD PMID:17982090 NCBI chr 1:226,737,472...226,764,647
Ensembl chr 1:226,739,318...226,764,625 		JBrowse link
G Akap6 A-kinase anchoring protein 6 multiple interactions
decreases expression		 ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of AKAP6 mRNA] CTD PMID:18200517 NCBI chr 6:70,184,101...70,624,369
Ensembl chr 6:70,184,175...70,619,738 		JBrowse link
G Akap9 A-kinase anchoring protein 9 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of AKAP9 mRNA CTD PMID:17982090 NCBI chr 4:30,056,738...30,192,716
Ensembl chr 4:30,056,738...30,192,606 		JBrowse link
G Akr1c2 aldo-keto reductase family 1, member C2 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of AKR1C2 mRNA CTD PMID:25724174 NCBI chr17:65,759,778...65,808,013
Ensembl chr17:65,759,788...65,775,764 		JBrowse link
G Alb albumin increases secretion EXP Trinitrobenzenesulfonic Acid results in increased secretion of ALB protein CTD PMID:23307618 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836 		JBrowse link
G Aldh1a3 aldehyde dehydrogenase 1 family, member A3 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of ALDH1A3 mRNA CTD PMID:17982090 NCBI chr 1:119,982,272...120,017,416
Ensembl chr 1:119,982,277...120,017,436 		JBrowse link
G Alpi alkaline phosphatase, intestinal increases activity
multiple interactions		 EXP Trinitrobenzenesulfonic Acid results in increased activity of ALPI protein
Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of ALPI protein]		 CTD PMID:15867298 NCBI chr 9:87,773,411...87,776,877
Ensembl chr 9:87,773,411...87,776,877 		JBrowse link
G Amy1 amylase alpha 1 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of AMY2A5 mRNA CTD PMID:17982090 NCBI chr 2:201,382,678...201,397,487
Ensembl chr 2:201,382,675...201,397,816 		JBrowse link
G Anxa1 annexin A1 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of ANXA1 mRNA CTD PMID:17982090 NCBI chr 1:217,861,175...217,877,205
Ensembl chr 1:217,861,175...217,877,343 		JBrowse link
G Anxa8 annexin A8 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of ANXA8 mRNA CTD PMID:17982090 NCBI chr16:9,397,144...9,412,072
Ensembl chr16:9,397,113...9,412,043 		JBrowse link
G Apbb1ip amyloid beta precursor protein binding family B member 1 interacting protein increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of APBB1IP mRNA CTD PMID:17982090 NCBI chr17:84,941,404...85,033,020
Ensembl chr17:84,982,243...85,033,010 		JBrowse link
G Apob apolipoprotein B decreases expression ISO Trinitrobenzenesulfonic Acid results in decreased expression of APOB mRNA CTD PMID:17982090 NCBI chr 6:30,844,386...30,883,983
Ensembl chr 6:30,844,368...30,892,497 		JBrowse link
G Aqp3 aquaporin 3 (Gill blood group) decreases expression ISO Trinitrobenzenesulfonic Acid results in decreased expression of AQP3 mRNA CTD PMID:15140218 NCBI chr 5:56,239,200...56,244,718
Ensembl chr 5:56,239,201...56,244,720 		JBrowse link
G Aqp4 aquaporin 4 increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of AQP4 mRNA CTD PMID:23537331 NCBI chr18:6,507,903...6,524,558
Ensembl chr18:6,507,903...6,524,856 		JBrowse link
G Arfip1 ARF interacting protein 1 increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of ARFIP1 mRNA CTD PMID:23537331 NCBI chr 2:169,843,804...169,924,136
Ensembl chr 2:169,843,801...169,923,142 		JBrowse link
G Arg1 arginase 1 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of ARG1 mRNA CTD PMID:17982090 NCBI chr 1:20,475,878...20,488,422
Ensembl chr 1:20,475,968...20,488,422 		JBrowse link
G Arg2 arginase 2 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of ARG2 mRNA CTD PMID:17982090 NCBI chr 6:97,936,002...97,961,379
Ensembl chr 6:97,936,002...97,961,378 		JBrowse link
G Arhgap24 Rho GTPase activating protein 24 multiple interactions
decreases expression		 ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of ARHGAP24 mRNA] CTD PMID:18200517 NCBI chr14:6,800,624...7,183,877
Ensembl chr14:6,800,631...7,183,823 		JBrowse link
G Arhgdib Rho GDP dissociation inhibitor beta multiple interactions
increases expression		 ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of ARHGDIB mRNA] CTD PMID:18200517 NCBI chr 4:169,822,951...169,841,884
Ensembl chr 4:169,822,952...169,841,658 		JBrowse link
G Arl4d ARF like GTPase 4D increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of ARL4D mRNA CTD PMID:23537331 NCBI chr10:86,592,054...86,602,843
Ensembl chr10:86,595,661...86,602,836 		JBrowse link
G Arrb1 arrestin, beta 1 multiple interactions
increases expression		 EXP Mesalamine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of ARRB1 mRNA]; Mesalamine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of ARRB1 protein]; qingre zaoshi liangxue fang inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of ARRB1 mRNA]; qingre zaoshi liangxue fang inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of ARRB1 protein]
Trinitrobenzenesulfonic Acid results in increased expression of ARRB1 mRNA; Trinitrobenzenesulfonic Acid results in increased expression of ARRB1 protein		 CTD PMID:24637189 NCBI chr 1:153,837,964...153,912,111
Ensembl chr 1:153,838,078...153,904,061 		JBrowse link
G Atoh1 atonal bHLH transcription factor 1 decreases expression ISO Trinitrobenzenesulfonic Acid results in decreased expression of ATOH1 mRNA CTD PMID:17982090 NCBI chr 4:93,912,068...93,914,163
Ensembl chr 4:93,912,068...93,914,154 		JBrowse link
G Atp2a2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 decreases expression EXP Trinitrobenzenesulfonic Acid results in decreased expression of ATP2A2 mRNA; Trinitrobenzenesulfonic Acid results in decreased expression of ATP2A2 protein CTD PMID:17131044 NCBI chr12:34,072,710...34,122,142
Ensembl chr12:34,072,683...34,122,101 		JBrowse link
G Atp4a ATPase H+/K+ transporting subunit alpha increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of ATP4A mRNA CTD PMID:17982090 NCBI chr 1:85,961,607...85,974,972
Ensembl chr 1:85,961,708...85,974,844 		JBrowse link
G Bak1 BCL2-antagonist/killer 1 multiple interactions
increases expression		 EXP Losartan inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of BAK1 mRNA] CTD PMID:15502641 NCBI chr20:5,100,480...5,109,669
Ensembl chr20:5,100,480...5,109,264 		JBrowse link
G Basp1 brain abundant, membrane attached signal protein 1 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of BASP1 mRNA CTD PMID:17982090 NCBI chr 2:75,816,130...75,863,801
Ensembl chr 2:75,816,122...75,864,043 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions
increases expression		 EXP
ISO		 dapagliflozin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of BAX protein]; Losartan inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of BAX mRNA]; Methylene Blue inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of BAX protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of BAX protein]; Telmisartan inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of BAX mRNA]
D-JNKI-1 inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of BAX protein]
Trinitrobenzenesulfonic Acid results in increased expression of BAX mRNA; Trinitrobenzenesulfonic Acid results in increased expression of BAX protein		 CTD PMID:15502641 PMID:22427801 PMID:24831514 PMID:31428839 PMID:33412153 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions
decreases expression
increases expression
decreases abundance		 EXP dapagliflozin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of BCL2 protein]; Losartan promotes the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of BCL2 mRNA]; Mesalamine inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of BCL2 protein]; Mesalamine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of BCL2 mRNA]; Mesalamine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of BCL2 protein]; Methylene Blue inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of BCL2 protein]; qingre zaoshi liangxue fang inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of BCL2 mRNA]; qingre zaoshi liangxue fang inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of BCL2 protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of BCL2 protein]; Telmisartan inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of BCL2 mRNA]
Trinitrobenzenesulfonic Acid results in decreased expression of BCL2 mRNA; Trinitrobenzenesulfonic Acid results in decreased expression of BCL2 protein
Trinitrobenzenesulfonic Acid results in increased expression of BCL2 mRNA; Trinitrobenzenesulfonic Acid results in increased expression of BCL2 protein
2,4,6-trinitrobenzenesulfonic acid decreases abundance of Bcl-2 protein in rat colon		 CTD
RGD		 PMID:15502641 PMID:24637189 PMID:24831514 PMID:31428839 PMID:33412153 More... RGD:152995414 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Bcl2a1 BCL2-related protein A1 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of BCL2A1B mRNA CTD PMID:17982090 NCBI chr 8:89,716,914...89,724,998
Ensembl chr 8:89,716,914...89,724,998 		JBrowse link
G Bcl2l11 Bcl2-like 11 multiple interactions
increases expression		 ISO [Trinitrobenzenesulfonic Acid results in increased expression of MAPK9 protein] promotes the reaction [BCL2L11 protein binds to MAPK9 protein]; D-JNKI-1 inhibits the reaction [[Trinitrobenzenesulfonic Acid results in increased expression of MAPK9 protein] promotes the reaction [BCL2L11 protein binds to MAPK9 protein]]; D-JNKI-1 inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of BCL2L11 protein]
Trinitrobenzenesulfonic Acid results in increased expression of BCL2L11 protein		 CTD PMID:22427801 NCBI chr 3:115,366,783...115,404,068
Ensembl chr 3:115,366,646...115,404,068 		JBrowse link
G Bcl3 BCL3, transcription coactivator multiple interactions
increases expression		 ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of BCL3 mRNA] CTD PMID:18200517 NCBI chr 1:79,471,368...79,485,908
Ensembl chr 1:79,471,369...79,485,607 		JBrowse link
G Becn1 beclin 1 multiple interactions
increases expression		 EXP dapagliflozin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of BECN1 protein]; Hydroxamic Acids analog promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of BECN1 protein]; Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of BECN1 protein] CTD PMID:30503585 PMID:33412153 NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742 		JBrowse link
G Bglap bone gamma-carboxyglutamate protein decreases expression ISO Trinitrobenzenesulfonic Acid results in decreased expression of BGLAP protein CTD PMID:23747339 NCBI chr 2:173,838,518...173,839,495
Ensembl chr 2:173,838,518...173,839,495 		JBrowse link
G Bgn biglycan increases expression
multiple interactions		 ISO Trinitrobenzenesulfonic Acid results in increased expression of BGN mRNA
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of BGN mRNA]		 CTD PMID:18200517 NCBI chr  X:151,197,296...151,209,458
Ensembl chr  X:151,197,273...151,209,461 		JBrowse link
G Bpnt2 3'(2'), 5'-bisphosphate nucleotidase 2 decreases expression ISO Trinitrobenzenesulfonic Acid results in decreased expression of BPNT2 mRNA CTD PMID:17982090 NCBI chr 5:17,775,684...17,802,570
Ensembl chr 5:17,772,608...17,802,570 		JBrowse link
G C1qb complement C1q B chain multiple interactions
increases expression		 ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of C1QB mRNA] CTD PMID:17982090 PMID:18200517 NCBI chr 5:149,118,843...149,124,394
Ensembl chr 5:149,118,846...149,124,407 		JBrowse link
G C1qc complement C1q C chain increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of C1QC mRNA CTD PMID:17982090 NCBI chr 5:149,127,412...149,130,757
Ensembl chr 5:149,127,415...149,131,017 		JBrowse link
G C3 complement C3 multiple interactions
increases expression		 ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of C3 mRNA] CTD PMID:17982090 PMID:18200517 NCBI chr 9:2,087,437...2,114,366
Ensembl chr 9:2,087,437...2,114,429 		JBrowse link
G C4b complement C4B increases expression
multiple interactions		 ISO Trinitrobenzenesulfonic Acid results in increased expression of C4B mRNA
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of C4B mRNA]		 CTD PMID:18200517 NCBI chr20:4,197,371...4,211,684
Ensembl chr20:4,197,366...4,211,681 		JBrowse link
G Cab39 calcium binding protein 39 decreases expression EXP Trinitrobenzenesulfonic Acid results in decreased expression of CAB39 mRNA CTD PMID:12163651 NCBI chr 9:86,463,095...86,524,545
Ensembl chr 9:86,463,095...86,524,544 		JBrowse link
G Cacna1c calcium voltage-gated channel subunit alpha1 C increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of CACNA1C mRNA; Trinitrobenzenesulfonic Acid results in increased expression of CACNA1C protein CTD PMID:23537331 NCBI chr 4:151,764,138...152,379,454
Ensembl chr 4:151,764,138...152,379,648 		JBrowse link
G Cacna1e calcium voltage-gated channel subunit alpha1 E increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of CACNA1E mRNA; Trinitrobenzenesulfonic Acid results in increased expression of CACNA1E protein CTD PMID:23537331 NCBI chr13:66,574,659...67,063,443
Ensembl chr13:66,581,920...66,894,450 		JBrowse link
G Calcb calcitonin-related polypeptide, beta decreases expression EXP Trinitrobenzenesulfonic Acid results in decreased expression of CALCB mRNA CTD PMID:21808981 NCBI chr 1:168,965,383...168,970,259
Ensembl chr 1:168,966,465...168,970,125 		JBrowse link
G Calcrl calcitonin receptor like receptor increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of CALCRL mRNA CTD PMID:21808981 NCBI chr 3:69,428,348...69,525,910
Ensembl chr 3:69,430,120...69,525,910 		JBrowse link
G Camk2b calcium/calmodulin-dependent protein kinase II beta decreases expression EXP Trinitrobenzenesulfonic Acid results in decreased expression of CAMK2B mRNA CTD PMID:23537331 NCBI chr14:80,845,206...80,934,172
Ensembl chr14:80,845,238...80,933,994 		JBrowse link
G Capg capping actin protein, gelsolin like multiple interactions
increases expression		 ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CAPG mRNA] CTD PMID:18200517 NCBI chr 4:104,594,743...104,611,856
Ensembl chr 4:104,594,753...104,611,856 		JBrowse link
G Capn1 calpain 1 multiple interactions
increases expression		 EXP Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CAPN1 protein] CTD PMID:30503585 NCBI chr 1:203,275,912...203,300,848
Ensembl chr 1:203,277,344...203,300,177 		JBrowse link
G Car3 carbonic anhydrase 3 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of CAR3 mRNA CTD PMID:17982090 NCBI chr 2:86,770,418...86,780,011
Ensembl chr 2:86,770,420...86,784,280 		JBrowse link
G Casp1 caspase 1 multiple interactions
increases expression		 EXP bergenin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of and results in increased cleavage of CASP1 protein]; Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CASP1 protein modified form]; Trinitrobenzenesulfonic Acid results in increased expression of and results in increased cleavage of CASP1 protein CTD PMID:30365937 PMID:30503585 NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383 		JBrowse link
G Casp12 caspase 12 multiple interactions
increases cleavage		 EXP Hydroxamic Acids analog promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CASP12 protein modified form]; Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased cleavage of CASP12 protein] CTD PMID:30503585 NCBI chr 8:2,642,296...2,669,549
Ensembl chr 8:2,642,434...2,674,037 		JBrowse link
G Casp3 caspase 3 multiple interactions
increases expression		 ISO
EXP		 D-JNKI-1 inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of CASP3 protein]; Trinitrobenzenesulfonic Acid results in increased cleavage of and results in increased activity of CASP3 protein
dapagliflozin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of and results in increased cleavage of CASP3 protein]; geraniol inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CASP3 protein]; Mesalamine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of and results in increased cleavage of CASP3 protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CASP3 protein]; Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CASP3 protein modified form]; Telmisartan inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of and results in increased activity of CASP3 protein]; Telmisartan inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CASP3 mRNA]; Trinitrobenzenesulfonic Acid results in increased activity of and results in increased cleavage of CASP3 protein; Trinitrobenzenesulfonic Acid results in increased expression of and results in increased activity of CASP3 protein
Trinitrobenzenesulfonic Acid results in increased expression of CASP3 mRNA; Trinitrobenzenesulfonic Acid results in increased expression of CASP3 protein; Trinitrobenzenesulfonic Acid results in increased expression of CASP3 protein modified form		 CTD PMID:22427801 PMID:24831514 PMID:26165751 PMID:30503585 PMID:33412153 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casp4 caspase 4 multiple interactions EXP bergenin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of and results in increased cleavage of CASP4 protein]; Trinitrobenzenesulfonic Acid results in increased expression of and results in increased cleavage of CASP4 protein CTD PMID:30365937 NCBI chr 8:2,599,017...2,635,097
Ensembl chr 8:2,598,876...2,635,092 		JBrowse link
G Casp8 caspase 8 multiple interactions
decreases expression		 EXP Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of CASP8 protein modified form] CTD PMID:30503585 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542 		JBrowse link
G Casp9 caspase 9 increases expression
multiple interactions		 EXP Trinitrobenzenesulfonic Acid results in increased expression of CASP9 protein modified form
Hydroxamic Acids analog promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CASP9 protein modified form]; Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CASP9 protein modified form]		 CTD PMID:30503585 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626 		JBrowse link
G Cat catalase increases expression
decreases expression
multiple interactions		 ISO
EXP		 Trinitrobenzenesulfonic Acid results in increased expression of CAT mRNA
Trinitrobenzenesulfonic Acid results in decreased expression of CAT mRNA
Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of CAT mRNA]		 CTD PMID:17982090 PMID:30503585 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 increases expression
multiple interactions
increases secretion		 ISO
EXP		 Trinitrobenzenesulfonic Acid results in increased expression of CCL2 mRNA; Trinitrobenzenesulfonic Acid results in increased expression of CCL2 protein
Active Hexose Correlated Compound inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CCL2 mRNA]; Hydroxamic Acids analog promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CCL2 mRNA]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CCL2 mRNA]; Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CCL2 mRNA]
icilin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CCL2 protein]
Trinitrobenzenesulfonic Acid results in increased secretion of CCL2 protein		 CTD PMID:17449585 PMID:17982090 PMID:23307618 PMID:23596210 PMID:30503585 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226 		JBrowse link
G Ccl3 C-C motif chemokine ligand 3 multiple interactions
increases expression		 ISO [cholan-2,3,24-tryl-2,3,24-trisulfate binds to and results in increased activity of NR1I2 protein] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CCL3 protein]; [rifaximin binds to and results in increased activity of NR1I2 protein] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CCL3 protein]; cholan-2,3,24-tryl-2,3,24-trisulfate inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CCL3 protein]; icilin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CCL3 protein]; rifaximin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CCL3 protein] CTD PMID:21599020 PMID:23596210 NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938 		JBrowse link
G Ccl4 C-C motif chemokine ligand 4 multiple interactions
increases expression		 ISO icilin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CCL4 protein] CTD PMID:23596210 NCBI chr10:68,466,394...68,468,229
Ensembl chr10:68,452,052...68,468,231 		JBrowse link
G Ccl7 C-C motif chemokine ligand 7 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of CCL7 mRNA CTD PMID:17982090 NCBI chr10:67,016,446...67,018,296
Ensembl chr10:67,016,446...67,018,303 		JBrowse link
G Ccn2 cellular communication network factor 2 multiple interactions
increases expression		 ISO stattic inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CCN2 mRNA] CTD PMID:25740948 NCBI chr 1:20,802,199...20,805,315
Ensembl chr 1:20,802,199...20,805,734 		JBrowse link
G Ccn4 cellular communication network factor 4 multiple interactions
increases expression
decreases expression		 ISO
EXP		 NOS2 gene mutant form inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CCN4 mRNA]
Trinitrobenzenesulfonic Acid results in decreased expression of CCN4 mRNA		 CTD PMID:19238344 PMID:23537331 NCBI chr 7:98,645,238...98,677,253
Ensembl chr 7:98,645,182...98,677,248 		JBrowse link
G Ccnb1 cyclin B1 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of CCNB1 mRNA CTD PMID:17982090 NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172 		JBrowse link
G Ccr2 C-C motif chemokine receptor 2 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of CCR2 mRNA CTD PMID:17982090 NCBI chr 8:123,734,465...123,742,483
Ensembl chr 8:123,734,430...123,742,100 		JBrowse link
G Ccr5 C-C motif chemokine receptor 5 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of CCR5 mRNA CTD PMID:15973123 PMID:17982090 NCBI chr 8:123,752,423...123,757,538
Ensembl chr 8:123,752,325...123,759,260 		JBrowse link
G Cd14 CD14 molecule increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of CD14 mRNA CTD PMID:17982090 NCBI chr18:28,335,522...28,337,383
Ensembl chr18:28,335,340...28,337,261 		JBrowse link
G Cd3g CD3 gamma subunit of T-cell receptor complex decreases expression EXP Trinitrobenzenesulfonic Acid results in decreased expression of CD3G mRNA CTD PMID:23537331 NCBI chr 8:45,280,797...45,287,271
Ensembl chr 8:45,281,204...45,287,147 		JBrowse link
G Cd44 CD44 molecule multiple interactions
increases expression		 ISO seryl-leucyl-isoleucyl-glycyl--arginyl-leucinamide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CD44 protein] CTD PMID:11717450 NCBI chr 3:89,155,850...89,244,615
Ensembl chr 3:89,157,058...89,244,620 		JBrowse link
G Cd47 Cd47 molecule multiple interactions
increases expression		 ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CD47 mRNA] CTD PMID:18200517 NCBI chr11:50,906,052...50,970,000
Ensembl chr11:50,906,177...50,969,425 		JBrowse link
G Cd53 Cd53 molecule increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of CD53 mRNA CTD PMID:17982090 NCBI chr 2:194,352,139...194,399,668
Ensembl chr 2:194,352,139...194,399,657 		JBrowse link
G Cd79a CD79a molecule increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of CD79A mRNA CTD PMID:17982090 NCBI chr 1:80,493,581...80,497,936
Ensembl chr 1:80,493,581...80,497,935 		JBrowse link
G Cdh17 cadherin 17 increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of CDH17 mRNA CTD PMID:12163651 NCBI chr 5:25,262,820...25,314,884
Ensembl chr 5:25,262,758...25,314,884 		JBrowse link
G Cdr2 cerebellar degeneration-related protein 2 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of CDR2 mRNA CTD PMID:17982090 NCBI chr 1:175,502,837...175,527,746
Ensembl chr 1:175,502,838...175,537,472 		JBrowse link
G Ceacam4 CEA cell adhesion molecule 4 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of CEACAM10 mRNA CTD PMID:17982090 NCBI chr 1:80,376,667...80,382,943
Ensembl chr 1:80,376,648...80,382,915 		JBrowse link
G Cebpb CCAAT/enhancer binding protein beta multiple interactions
increases expression		 ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CEBPB mRNA] CTD PMID:18200517 NCBI chr 3:156,398,035...156,399,466
Ensembl chr 3:156,397,052...156,399,473 		JBrowse link
G Cel carboxyl ester lipase increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of CEL mRNA CTD PMID:17982090 NCBI chr 3:11,883,532...11,891,035
Ensembl chr 3:11,883,532...11,891,035 		JBrowse link
G Cela2a chymotrypsin like elastase 2A increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of CELA2A mRNA CTD PMID:17982090 NCBI chr 5:154,126,879...154,136,630
Ensembl chr 5:154,126,878...154,136,632 		JBrowse link
G Ces1d carboxylesterase 1D increases expression
multiple interactions
decreases expression		 ISO Trinitrobenzenesulfonic Acid results in increased expression of CES1 mRNA
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of CES1 mRNA]		 CTD PMID:18200517 PMID:19524605 PMID:22609641 NCBI chr19:13,873,490...13,912,035
Ensembl chr19:13,796,623...13,912,035 		JBrowse link
G Ces3a carboxylesterase 3a decreases expression
multiple interactions		 ISO Trinitrobenzenesulfonic Acid results in decreased expression of CES3 mRNA
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of CES3 mRNA]		 CTD PMID:17982090 PMID:18200517 NCBI chr19:32,992,386...33,000,562 JBrowse link
G Cfd complement factor D decreases expression ISO Trinitrobenzenesulfonic Acid results in decreased expression of CFD mRNA CTD PMID:17982090 NCBI chr 7:9,813,148...9,814,871
Ensembl chr 7:9,813,150...9,815,053 		JBrowse link
G Cfh complement factor H increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of CFH mRNA CTD PMID:17982090 NCBI chr13:51,512,376...51,613,829
Ensembl chr13:51,511,828...51,613,838 		JBrowse link
G Chi3l1 chitinase 3 like 1 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of CHI3L1 mRNA CTD PMID:17982090 NCBI chr13:45,641,802...45,649,787
Ensembl chr13:45,641,802...45,649,787 		JBrowse link
G Chkb choline kinase beta decreases expression ISO Trinitrobenzenesulfonic Acid results in decreased expression of CHKB mRNA CTD PMID:17982090 NCBI chr 7:120,500,960...120,504,359
Ensembl chr 7:120,500,984...120,504,461 		JBrowse link
G Clca1 chloride channel accessory 1 decreases expression ISO Trinitrobenzenesulfonic Acid results in decreased expression of CLCA1 mRNA CTD PMID:17982090 NCBI chr 2:233,938,677...233,964,369
Ensembl chr 2:233,938,677...233,964,369 		JBrowse link
G Clca4 chloride channel accessory 4 multiple interactions
increases expression		 ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CLCA4A mRNA] CTD PMID:18200517 NCBI chr 2:233,883,625...233,904,993
Ensembl chr 2:233,883,851...233,903,089 		JBrowse link
G Cldn1 claudin 1 multiple interactions
decreases expression		 ISO ginsenoside Re inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of CLDN1 protein]; TES protein inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of CLDN1 protein] CTD PMID:22849695 PMID:39237074 NCBI chr11:74,421,569...74,436,728
Ensembl chr11:74,421,569...74,436,724 		JBrowse link
G Cldn2 claudin 2 multiple interactions
decreases expression		 EXP oxymatrine inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of CLDN2 mRNA]; oxymatrine inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of CLDN2 protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of CLDN2 mRNA]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of CLDN2 protein]
Trinitrobenzenesulfonic Acid results in decreased expression of CLDN2 mRNA; Trinitrobenzenesulfonic Acid results in decreased expression of CLDN2 protein		 CTD PMID:35290143 NCBI chr  X:103,459,870...103,473,794
Ensembl chr  X:103,459,780...103,474,838 		JBrowse link
G Col1a1 collagen type I alpha 1 chain multiple interactions
increases expression		 ISO stattic inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of COL1A1 mRNA] CTD PMID:17982090 PMID:25740948 NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624 		JBrowse link
G Col1a2 collagen type I alpha 2 chain multiple interactions
increases expression		 ISO 6-diphenylmethyl-5-(5-isopropyl-2-methoxybenzylamino)-1-azabicyclo(2.2.2)octane-3-carboxylic acid inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of COL1A2 mRNA]; Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of COL1A2 mRNA]; TACR1 gene mutant form inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of COL1A2 mRNA] CTD PMID:17982090 PMID:18200517 PMID:20889569 NCBI chr 4:32,563,938...32,598,868
Ensembl chr 4:32,563,381...32,598,867 		JBrowse link
G Col4a1 collagen type IV alpha 1 chain multiple interactions
increases expression		 ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of COL4A1 mRNA] CTD PMID:17982090 PMID:18200517 NCBI chr16:78,183,533...78,294,412
Ensembl chr16:78,183,533...78,294,412 		JBrowse link
G Col4a2 collagen type IV alpha 2 chain multiple interactions
increases expression		 ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of COL4A2 mRNA] CTD PMID:18200517 NCBI chr16:78,047,591...78,183,360
Ensembl chr16:78,047,602...78,183,839 		JBrowse link
G Col5a1 collagen type V alpha 1 chain multiple interactions
increases expression		 ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of COL5A1 mRNA] CTD PMID:18200517 NCBI chr 3:11,208,429...11,356,715
Ensembl chr 3:11,208,512...11,354,588 		JBrowse link
G Col5a2 collagen type V alpha 2 chain multiple interactions
increases expression		 ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of COL5A2 mRNA] CTD PMID:18200517 NCBI chr 9:47,448,741...47,598,134
Ensembl chr 9:47,448,736...47,598,154 		JBrowse link
G Cort cortistatin increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of CORT protein CTD PMID:11959675 NCBI chr 5:159,560,591...159,562,032 JBrowse link
G Crh corticotropin releasing hormone decreases expression
increases expression		 EXP Trinitrobenzenesulfonic Acid results in decreased expression of CRH mRNA
Trinitrobenzenesulfonic Acid results in increased expression of CRH mRNA		 CTD PMID:11668029 PMID:11959675 NCBI chr 2:102,143,055...102,144,919
Ensembl chr 2:102,143,055...102,144,919 		JBrowse link
G Crhr1 corticotropin releasing hormone receptor 1 increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of CRHR1 mRNA CTD PMID:15178552 NCBI chr10:89,040,186...89,083,481
Ensembl chr10:89,040,203...89,083,481 		JBrowse link
G Crisp3 cysteine-rich secretory protein 3 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of CRISP3 mRNA CTD PMID:17982090 NCBI chr 9:20,432,051...20,472,663
Ensembl chr 9:20,450,908...20,472,658 		JBrowse link
G Csf2rb colony stimulating factor 2 receptor subunit beta multiple interactions
increases expression		 ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CSF2RB mRNA] CTD PMID:18200517 NCBI chr 7:109,876,919...109,901,589
Ensembl chr 7:109,886,425...109,904,157 		JBrowse link
G Csf3 colony stimulating factor 3 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of CSF3 protein CTD PMID:23596210 NCBI chr10:83,660,787...83,664,569
Ensembl chr10:83,661,207...83,663,603 		JBrowse link
G Ctnnb1 catenin beta 1 multiple interactions
increases expression		 EXP geraniol inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CTNNB1 mRNA]; geraniol inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CTNNB1 protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CTNNB1 mRNA]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CTNNB1 protein]
Trinitrobenzenesulfonic Acid results in increased expression of CTNNB1 mRNA; Trinitrobenzenesulfonic Acid results in increased expression of CTNNB1 protein		 CTD PMID:26165751 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111 		JBrowse link
G Ctrl chymotrypsin-like decreases expression ISO Trinitrobenzenesulfonic Acid results in decreased expression of CTRB1 mRNA CTD PMID:17982090 NCBI chr19:33,827,279...33,829,129
Ensembl chr19:33,827,229...33,833,626 		JBrowse link
G Ctsc cathepsin C increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of CTSC mRNA CTD PMID:17982090 NCBI chr 1:142,028,386...142,059,841
Ensembl chr 1:142,028,392...142,060,387 		JBrowse link
G Cx3cl1 C-X3-C motif chemokine ligand 1 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of CX3CL1 mRNA CTD PMID:15973123 NCBI chr19:10,227,337...10,237,826
Ensembl chr19:10,227,340...10,236,833 		JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of CXCL10 protein CTD PMID:23596210 NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975 		JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of CXCL12 mRNA CTD PMID:15973123 NCBI chr 4:150,388,326...150,401,173
Ensembl chr 4:150,388,325...150,401,168 		JBrowse link
G Cxcl13 C-X-C motif chemokine ligand 13 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of CXCL13 mRNA CTD PMID:15973123 NCBI chr14:13,608,894...13,613,965
Ensembl chr14:13,608,902...13,613,933 		JBrowse link
G Cxcl14 C-X-C motif chemokine ligand 14 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of CXCL14 mRNA CTD PMID:15973123 NCBI chr17:8,317,930...8,325,956
Ensembl chr17:8,317,933...8,324,839 		JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 multiple interactions
increases expression		 ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CXCL2 mRNA] CTD PMID:17375199 PMID:18200517 NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075 		JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 multiple interactions
increases expression		 ISO icilin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CXCL1 protein]
Trinitrobenzenesulfonic Acid results in increased expression of CXCL1 mRNA; Trinitrobenzenesulfonic Acid results in increased expression of CXCL1 protein		 CTD PMID:17982090 PMID:23596210 NCBI chr14:17,287,727...17,289,451
Ensembl chr14:17,270,146...17,289,511 		JBrowse link
G Cxcl9 C-X-C motif chemokine ligand 9 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of CXCL9 mRNA CTD PMID:17982090 NCBI chr14:15,722,868...15,727,779
Ensembl chr14:15,722,908...15,728,435 		JBrowse link
G Cxcr2 C-X-C motif chemokine receptor 2 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of CXCR2 mRNA CTD PMID:15973123 NCBI chr 9:75,729,493...75,735,868
Ensembl chr 9:75,729,115...75,739,425 		JBrowse link
G Cycs cytochrome c, somatic multiple interactions
increases expression		 EXP Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CYCS protein]; Telmisartan inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CYCS mRNA]
Trinitrobenzenesulfonic Acid results in increased expression of CYCS mRNA; Trinitrobenzenesulfonic Acid results in increased expression of CYCS protein		 CTD PMID:24831514 PMID:30503585 NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054
Ensembl chr18:79,651,378...79,654,054 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions EXP Trinitrobenzenesulfonic Acid results in decreased activity of and results in decreased expression of CYP1A2 protein CTD PMID:18079364 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312 		JBrowse link
G Cyp2c11 cytochrome P450, subfamily 2, polypeptide 11 multiple interactions EXP gadolinium chloride inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased activity of and results in decreased expression of CYP2C11 protein]; Polymyxin B inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased activity of and results in decreased expression of CYP2C11 protein]; Trinitrobenzenesulfonic Acid results in decreased activity of and results in decreased expression of CYP2C11 protein CTD PMID:18079364 NCBI chr 1:236,762,719...236,799,069
Ensembl chr 1:236,762,842...236,799,066 		JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions EXP Trinitrobenzenesulfonic Acid results in decreased activity of and results in decreased expression of CYP2E1 protein CTD PMID:18079364 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 multiple interactions EXP gadolinium chloride inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased activity of and results in decreased expression of CYP3A2 protein]; nimesulide inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased activity of and results in decreased expression of CYP3A2 protein]; Polymyxin B inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased activity of and results in decreased expression of CYP3A2 protein]; Trinitrobenzenesulfonic Acid results in decreased activity of and results in decreased expression of CYP3A2 protein CTD PMID:18079364 NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008 		JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 decreases expression ISO Trinitrobenzenesulfonic Acid results in decreased expression of CYP3A13 mRNA CTD PMID:17982090 NCBI chr12:16,806,222...16,846,428
Ensembl chr12:16,806,207...16,846,422 		JBrowse link
G Dcp2 decapping mRNA 2 decreases expression EXP Trinitrobenzenesulfonic Acid results in decreased expression of DCP2 mRNA CTD PMID:12163651 NCBI chr18:36,750,732...36,787,067
Ensembl chr18:36,750,732...36,788,557 		JBrowse link
G Defa5 defensin alpha 5 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of DEFA5 mRNA CTD PMID:17982090 NCBI chr16:70,342,530...70,344,854
Ensembl chr16:70,342,530...70,344,836 		JBrowse link
G Defb2 defensin beta 2 increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of DEFB2 mRNA CTD PMID:19998380 NCBI chr16:70,231,870...70,245,817
Ensembl chr16:70,231,945...70,245,784 		JBrowse link
G Dnaaf5 dynein, axonemal, assembly factor 5 decreases expression ISO Trinitrobenzenesulfonic Acid results in decreased expression of DNAAF5 mRNA CTD PMID:17982090 NCBI chr12:15,453,636...15,492,722
Ensembl chr12:15,453,636...15,492,739 		JBrowse link
G Dpp4 dipeptidylpeptidase 4 increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of DPP4 mRNA CTD PMID:12163651 NCBI chr 3:46,962,233...47,043,870
Ensembl chr 3:46,962,243...47,043,901 		JBrowse link
G Dsg2 desmoglein 2 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of DSG2 mRNA CTD PMID:17982090 NCBI chr18:11,846,207...11,904,630
Ensembl chr18:11,846,183...11,904,156 		JBrowse link
G Eef1a1 eukaryotic translation elongation factor 1 alpha 1 decreases expression EXP Trinitrobenzenesulfonic Acid results in decreased expression of EEF1A1 mRNA CTD PMID:12163651 NCBI chr 8:79,341,554...79,344,784
Ensembl chr 8:79,341,557...79,344,839 		JBrowse link
G Eif4a2 eukaryotic translation initiation factor 4A2 decreases expression EXP Trinitrobenzenesulfonic Acid results in decreased expression of EIF4A2 mRNA CTD PMID:12163651 NCBI chr11:77,764,126...77,770,810
Ensembl chr11:77,764,124...77,770,781 		JBrowse link
G Eif4ebp2 eukaryotic translation initiation factor 4E binding protein 2 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of EIF4EBP2 mRNA CTD PMID:17982090 NCBI chr20:29,379,444...29,400,110
Ensembl chr20:29,382,668...29,399,946 		JBrowse link
G Emb embigin multiple interactions
increases expression		 ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of EMB mRNA] CTD PMID:18200517 NCBI chr 2:49,070,509...49,125,042
Ensembl chr 2:49,069,087...49,125,050 		JBrowse link
G Ephb3 Eph receptor B3 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of EPHB3 mRNA CTD PMID:17982090 NCBI chr11:79,840,668...79,859,345
Ensembl chr11:79,840,668...79,859,370 		JBrowse link
G Fabp2 fatty acid binding protein 2 decreases expression ISO Trinitrobenzenesulfonic Acid results in decreased expression of FABP2 mRNA CTD PMID:17982090 NCBI chr 2:211,040,032...211,044,089
Ensembl chr 2:211,040,032...211,044,089 		JBrowse link
G Faslg Fas ligand multiple interactions
increases expression		 ISO D-JNKI-1 inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of FASL protein]
Trinitrobenzenesulfonic Acid results in increased expression of FASL protein		 CTD PMID:22427801 NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215 		JBrowse link
G Fbln2 fibulin 2 multiple interactions
increases expression		 ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of FBLN2 mRNA] CTD PMID:18200517 NCBI chr 4:123,704,289...123,763,857
Ensembl chr 4:123,704,373...123,763,948 		JBrowse link
G Fbxl2 F-box and leucine-rich repeat protein 2 increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of FBXL2 mRNA CTD PMID:12163651 NCBI chr 8:113,916,660...113,965,137
Ensembl chr 8:113,913,373...113,965,066 		JBrowse link
G Fcgr2b Fc gamma receptor 2B increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of FCGR2B mRNA CTD PMID:19524605 NCBI chr13:83,191,253...83,207,778
Ensembl chr13:83,193,163...83,207,778 		JBrowse link
G Fcgr3a Fc gamma receptor 3A multiple interactions
increases expression		 ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of FCGR3A mRNA] CTD PMID:18200517 NCBI chr13:83,249,905...83,259,921
Ensembl chr13:83,249,872...83,259,921 		JBrowse link
G Fgf17 fibroblast growth factor 17 decreases expression EXP Trinitrobenzenesulfonic Acid results in decreased expression of FGF17 mRNA CTD PMID:23537331 NCBI chr15:45,711,498...45,717,622
Ensembl chr15:45,711,998...45,717,063 		JBrowse link
G Fgfr3 fibroblast growth factor receptor 3 increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of FGFR3 mRNA CTD PMID:23537331 NCBI chr14:76,987,242...77,002,671
Ensembl chr14:76,987,993...77,003,341 		JBrowse link
G Fn1 fibronectin 1 multiple interactions
increases expression		 ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of FN1 mRNA] CTD PMID:18200517 NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of FOS mRNA CTD PMID:15178552 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036 		JBrowse link
G Fstl1 follistatin-like 1 multiple interactions
increases expression		 ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of FSTL1 mRNA] CTD PMID:18200517 NCBI chr11:62,895,391...62,948,581
Ensembl chr11:62,779,783...62,948,677 		JBrowse link
G Fxyd5 FXYD domain-containing ion transport regulator 5 decreases expression EXP Trinitrobenzenesulfonic Acid results in decreased expression of FXYD5 mRNA CTD PMID:23537331 NCBI chr 1:86,267,937...86,277,329
Ensembl chr 1:86,267,406...86,277,519 		JBrowse link
G Gabbr1 gamma-aminobutyric acid type B receptor subunit 1 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of GABBR1 mRNA CTD PMID:17982090 NCBI chr20:1,464,534...1,494,114
Ensembl chr20:1,464,534...1,493,994 		JBrowse link
G Gbp2 guanylate binding protein 2 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of GBP2 mRNA CTD PMID:17982090 NCBI chr 2:231,332,488...231,348,573
Ensembl chr 2:231,332,284...231,348,571 		JBrowse link
G Gbp4 guanylate binding protein 4 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of GBP3 mRNA CTD PMID:17982090 NCBI chr 2:231,304,910...231,318,883
Ensembl chr 2:231,305,244...231,318,879 		JBrowse link
G Gch1 GTP cyclohydrolase 1 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of GCH1 mRNA CTD PMID:17982090 NCBI chr15:20,404,267...20,437,727
Ensembl chr15:20,402,527...20,437,698 		JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit multiple interactions EXP [Trinitrobenzenesulfonic Acid co-treated with Ethanol] results in increased expression of GCLC mRNA CTD PMID:10830784 NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544 		JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of GCLM mRNA CTD PMID:22609641 NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535 		JBrowse link
G Gda guanine deaminase multiple interactions
increases expression		 ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of GDA mRNA] CTD PMID:18200517 NCBI chr 1:218,903,045...218,982,360
Ensembl chr 1:218,906,815...218,982,416 		JBrowse link
G Gdpd3 glycerophosphodiester phosphodiesterase domain containing 3 decreases expression ISO Trinitrobenzenesulfonic Acid results in decreased expression of GDPD3 mRNA CTD PMID:17982090 NCBI chr 1:181,373,505...181,383,063
Ensembl chr 1:181,366,626...181,383,063 		JBrowse link
G Ggta1 glycoprotein alpha-galactosyltransferase 1 increases expression
multiple interactions		 ISO Trinitrobenzenesulfonic Acid results in increased expression of GGTA1 mRNA
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of GGTA1 mRNA]		 CTD PMID:18200517 NCBI chr 3:18,732,985...18,824,916
Ensembl chr 3:18,732,991...18,809,908 		JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1 multiple interactions
decreases expression		 EXP Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of GOT1 mRNA] CTD PMID:30503585 NCBI chr 1:242,357,293...242,381,535
Ensembl chr 1:242,357,306...242,380,633 		JBrowse link
G Got1l1 glutamic-oxaloacetic transaminase 1-like 1 multiple interactions
decreases expression		 ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of GOT1L1 mRNA] CTD PMID:18200517 NCBI chr16:64,860,308...64,873,656
Ensembl chr16:64,860,704...64,866,162 		JBrowse link
G Got2 glutamic-oxaloacetic transaminase 2 decreases expression
multiple interactions		 EXP Trinitrobenzenesulfonic Acid results in decreased expression of GOT2 mRNA
Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of GOT2 mRNA]		 CTD PMID:30503585 NCBI chr19:9,174,304...9,199,995
Ensembl chr19:9,174,311...9,199,994 		JBrowse link
G Gpx2 glutathione peroxidase 2 decreases expression EXP Trinitrobenzenesulfonic Acid results in decreased expression of GPX2 mRNA CTD PMID:31669340 NCBI chr 6:95,493,589...95,496,877
Ensembl chr 6:95,493,589...95,496,877 		JBrowse link
G Grb10 growth factor receptor bound protein 10 multiple interactions
increases expression		 ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of GRB10 mRNA] CTD PMID:18200517 NCBI chr14:86,495,051...86,602,800
Ensembl chr14:86,495,054...86,602,806 		JBrowse link
G Grem1 gremlin 1, DAN family BMP antagonist increases expression
multiple interactions		 ISO Trinitrobenzenesulfonic Acid results in increased expression of GREM1 mRNA
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of GREM1 mRNA]		 CTD PMID:18200517 NCBI chr 3:100,512,317...100,524,001
Ensembl chr 3:100,512,313...100,524,082 		JBrowse link
G Gria2 glutamate ionotropic receptor AMPA type subunit 2 increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of GRIA2 mRNA CTD PMID:23537331 NCBI chr 2:165,949,379...166,069,510
Ensembl chr 2:165,947,521...166,069,510 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta increases expression
multiple interactions		 EXP Trinitrobenzenesulfonic Acid results in increased expression of GSK3B protein
geraniol inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of GSK3B protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of GSK3B protein]		 CTD PMID:26165751 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646 		JBrowse link
G Gsn gelsolin multiple interactions
decreases expression		 ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of GSN mRNA] CTD PMID:17982090 PMID:18200517 NCBI chr 3:18,585,166...18,638,404
Ensembl chr 3:18,585,172...18,638,402 		JBrowse link
G Gsr glutathione-disulfide reductase decreases activity
multiple interactions
decreases expression		 EXP Trinitrobenzenesulfonic Acid results in decreased activity of GSR protein
4-methylesculetin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased activity of GSR protein]; 4-methylesculetin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of GSR mRNA]		 CTD PMID:31669340 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661 		JBrowse link
G Gstm2 glutathione S-transferase mu 2 decreases expression ISO Trinitrobenzenesulfonic Acid results in decreased expression of GSTM2 mRNA CTD PMID:17982090 NCBI chr 2:195,624,015...195,628,774
Ensembl chr 2:195,544,426...195,628,961 		JBrowse link
G Gstt1 glutathione S-transferase theta 1 decreases expression EXP Trinitrobenzenesulfonic Acid results in decreased expression of GSTT1 mRNA CTD PMID:31669340 NCBI chr20:12,856,613...12,873,586
Ensembl chr20:12,856,669...12,873,585 		JBrowse link
G Havcr1 hepatitis A virus cellular receptor 1 increases expression
increases secretion		 EXP Trinitrobenzenesulfonic Acid results in increased expression of HAVCR1 mRNA
Trinitrobenzenesulfonic Acid results in increased secretion of HAVCR1 protein		 CTD PMID:23307618 NCBI chr10:31,118,667...31,151,730
Ensembl chr10:31,119,088...31,151,698 		JBrowse link
G Hbb-b2 hemoglobin, beta adult minor chain increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of HBB-B2 mRNA CTD PMID:17982090 NCBI chr 1:158,243,696...158,245,076
Ensembl chr 1:158,120,200...158,252,012 		JBrowse link
G Hebp2 heme binding protein 2 increases expression
multiple interactions		 ISO Trinitrobenzenesulfonic Acid results in increased expression of HEBP2 mRNA
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of HEBP2 mRNA]		 CTD PMID:18200517 NCBI chr 1:13,194,982...13,201,777
Ensembl chr 1:13,194,982...13,201,777 		JBrowse link
G Hmgb1 high mobility group box 1 multiple interactions
increases expression
increases abundance		 EXP dapagliflozin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of HMGB1 protein]; Mesalamine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of HMGB1 protein]
2,4,6-trinitrobenzenesulfonic acid increases abundance of Hmgb1 protein in rat colon		 CTD
RGD		 PMID:33412153 PMID:29572553 RGD:152995414 NCBI chr12:5,972,950...5,979,658
Ensembl chr12:5,901,586...5,978,565
Ensembl chr16:5,901,586...5,978,565 		JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of HMGCR mRNA CTD PMID:17982090 NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703 		JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions
increases expression
decreases expression		 EXP dapagliflozin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of HMOX1 protein]; Heme promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of and results in increased activity of HMOX1 protein]; Mesalamine inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of HMOX1 protein]; Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of HMOX1 protein]; Trinitrobenzenesulfonic Acid results in increased expression of and results in increased activity of HMOX1 protein; zinc protoporphyrin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of HMOX1 protein]
Trinitrobenzenesulfonic Acid results in increased expression of HMOX1 mRNA; Trinitrobenzenesulfonic Acid results in increased expression of HMOX1 protein		 CTD PMID:17292349 PMID:25469038 PMID:30503585 PMID:33412153 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Hoxd13 homeo box D13 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of HOXD13 mRNA CTD PMID:17982090 NCBI chr 3:59,570,647...59,573,963
Ensembl chr 3:59,570,646...59,573,963 		JBrowse link
G Hpgd 15-hydroxyprostaglandin dehydrogenase affects expression EXP Trinitrobenzenesulfonic Acid affects the expression of HPGD mRNA CTD PMID:25526689 NCBI chr16:33,986,265...34,024,228
Ensembl chr16:33,986,266...34,024,228 		JBrowse link
G Hrh4 histamine receptor H4 increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of HRH4 mRNA CTD PMID:24561612 NCBI chr18:4,166,270...4,182,426
Ensembl chr18:4,166,270...4,246,345 		JBrowse link
G Hsd11b1 hydroxysteroid 11-beta dehydrogenase 1 increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of HSD11B1 mRNA CTD PMID:21513799 NCBI chr13:104,728,539...104,798,884
Ensembl chr13:104,728,539...104,788,687 		JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 increases expression
multiple interactions		 EXP Trinitrobenzenesulfonic Acid results in increased expression of HSPA5 protein
Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of HSPA5 protein]		 CTD PMID:30503585 NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891 		JBrowse link
G Hspb7 heat shock protein family B (small) member 7 multiple interactions
increases expression		 ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of HSPB7 mRNA] CTD PMID:18200517 NCBI chr 5:153,727,782...153,731,268
Ensembl chr 5:153,727,588...153,731,266 		JBrowse link
G Htr1a 5-hydroxytryptamine receptor 1A increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of HTR1A mRNA CTD PMID:23537331 NCBI chr 2:36,693,462...36,698,026
Ensembl chr 2:36,694,174...36,695,442 		JBrowse link
G Htr2a 5-hydroxytryptamine receptor 2A increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of HTR2A mRNA CTD PMID:23537331 NCBI chr15:49,950,035...50,022,188
Ensembl chr15:49,950,804...50,020,928 		JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions
increases expression
increases abundance		 ISO
EXP		 Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of ICAM1 mRNA]
cinnamaldehyde inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of ICAM1 protein]; geraniol inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of ICAM1 protein]; hesperetin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of ICAM1 protein]; Hydroxamic Acids analog promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of ICAM1 mRNA]; Methylene Blue inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of ICAM1 protein]; Resveratrol inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of ICAM1 protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of ICAM1 protein]; Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of ICAM1 mRNA]
Trinitrobenzenesulfonic Acid results in increased expression of ICAM1 mRNA; Trinitrobenzenesulfonic Acid results in increased expression of ICAM1 protein
2,4,6-trinitrobenzenesulfonic acid increases abundance of Icam-1 protein in rat colon		 CTD
RGD		 PMID:18200517 PMID:22029500 PMID:26165751 PMID:30503585 PMID:31428839 More... RGD:152995414 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438 		JBrowse link
G Ido1 indoleamine 2,3-dioxygenase 1 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of IDO1 mRNA CTD PMID:17982090 NCBI chr16:67,430,654...67,442,726
Ensembl chr16:67,430,578...67,442,730 		JBrowse link
G Ifi27 interferon, alpha-inducible protein 27 decreases expression ISO Trinitrobenzenesulfonic Acid results in decreased expression of IFI27 mRNA CTD PMID:17982090 NCBI chr 6:122,590,461...122,596,996
Ensembl chr 6:122,590,472...122,779,294 		JBrowse link
G Ifi30 IFI30, lysosomal thiol reductase multiple interactions EXP [topiramate co-treated with Trinitrobenzenesulfonic Acid] results in decreased expression of IFI30 mRNA CTD PMID:21849664 NCBI chr16:18,675,590...18,679,655
Ensembl chr16:18,675,613...18,681,175 		JBrowse link
G Ifit2 interferon-induced protein with tetratricopeptide repeats 2 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of IFIT2 mRNA CTD PMID:17982090 NCBI chr 1:232,102,570...232,108,638
Ensembl chr 1:232,102,570...232,108,635 		JBrowse link
G Ifitm3 interferon induced transmembrane protein 3 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of IFITM3 mRNA CTD PMID:17982090 NCBI chr 1:196,111,026...196,112,135
Ensembl chr 1:196,111,043...196,112,203 		JBrowse link
G Ifnb1 interferon beta 1 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of IFNB1 mRNA CTD PMID:17375199 NCBI chr 5:103,020,758...103,021,595
Ensembl chr 5:103,020,969...103,021,523 		JBrowse link
G Ifng interferon gamma multiple interactions
increases expression
decreases expression		 EXP
ISO		 bergenin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IFNG protein]; Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IFNG mRNA]; Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IFNG protein]; Dexamethasone inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IFNG mRNA]; Dexamethasone inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IFNG protein]
Trinitrobenzenesulfonic Acid results in increased expression of IFNG mRNA; Trinitrobenzenesulfonic Acid results in increased expression of IFNG protein
[cholan-2,3,24-tryl-2,3,24-trisulfate binds to and results in increased activity of NR1I2 protein] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IFNG protein]; [rifaximin binds to and results in increased activity of NR1I2 protein] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IFNG protein]; cholan-2,3,24-tryl-2,3,24-trisulfate inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IFNG protein]; dai-kenchu-to inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IFNG]; Minocycline inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IFNG mRNA]; rifaximin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IFNG protein]; seryl-leucyl-isoleucyl-glycyl--arginyl-leucinamide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IFNG mRNA]; sinomenine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IFNG mRNA]; sinomenine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IFNG protein]
Trinitrobenzenesulfonic Acid results in increased expression of IFNG; Trinitrobenzenesulfonic Acid results in increased expression of IFNG mRNA; Trinitrobenzenesulfonic Acid results in increased expression of IFNG protein
Trinitrobenzenesulfonic Acid results in decreased expression of IFNG mRNA		 CTD PMID:11717450 PMID:15973123 PMID:16782535 PMID:16867261 PMID:19285099 More... NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375 		JBrowse link
G Igf1 insulin-like growth factor 1 multiple interactions
increases expression		 ISO
EXP		 6-diphenylmethyl-5-(5-isopropyl-2-methoxybenzylamino)-1-azabicyclo(2.2.2)octane-3-carboxylic acid inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IGF1 protein]; Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IGF1 mRNA]; TACR1 gene mutant form inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IGF1 protein]
Trinitrobenzenesulfonic Acid results in increased expression of IGF1 mRNA; Trinitrobenzenesulfonic Acid results in increased expression of IGF1 protein		 CTD PMID:18200517 PMID:20889569 PMID:24782617 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296 		JBrowse link
G Igfbp4 insulin-like growth factor binding protein 4 multiple interactions
increases expression		 ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IGFBP4 mRNA] CTD PMID:18200517 NCBI chr10:83,995,253...84,007,272
Ensembl chr10:83,989,591...84,007,225 		JBrowse link
G Igfbp5 insulin-like growth factor binding protein 5 multiple interactions
increases expression		 ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IGFBP5 mRNA] CTD PMID:17982090 PMID:18200517 NCBI chr 9:74,452,371...74,464,953
Ensembl chr 9:74,448,382...74,465,156 		JBrowse link
G Il10 interleukin 10 multiple interactions
decreases expression
increases expression
decreases secretion
decreases abundance		 EXP
ISO		 [iberogast analog co-treated with Trinitrobenzenesulfonic Acid] results in increased expression of IL10 mRNA; [iberogast co-treated with Trinitrobenzenesulfonic Acid] results in increased expression of IL10 mRNA; bergenin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL10 protein]; Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of IL10 mRNA]; dapagliflozin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of IL10 protein]; Isatin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of IL10]; Mesalamine inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of IL10 protein]; oxymatrine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL10 mRNA]; oxymatrine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL10 protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of IL10 mRNA]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of IL10 protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL10 mRNA]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL10 protein]; Telmisartan inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL10 protein]
[cholan-2,3,24-tryl-2,3,24-trisulfate co-treated with Trinitrobenzenesulfonic Acid] results in increased expression of IL10 protein; [rifaximin co-treated with Trinitrobenzenesulfonic Acid] results in increased expression of IL10 protein; seryl-leucyl-isoleucyl-glycyl--arginyl-leucinamide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL10 mRNA]; soyasaponin Ab inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of IL10 protein]
Trinitrobenzenesulfonic Acid results in decreased expression of IL10; Trinitrobenzenesulfonic Acid results in decreased expression of IL10 mRNA; Trinitrobenzenesulfonic Acid results in decreased expression of IL10 protein
Trinitrobenzenesulfonic Acid results in increased expression of IL10 mRNA; Trinitrobenzenesulfonic Acid results in increased expression of IL10 protein
Trinitrobenzenesulfonic Acid results in decreased secretion of IL10 protein
2,4,6-trinitrobenzenesulfonic acid decreases abundance of IL-10 protein in rat colon		 CTD
RGD		 PMID:11717450 PMID:15604057 PMID:15973123 PMID:16867261 PMID:17375199 More... RGD:152995414 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313 		JBrowse link
G Il12a interleukin 12A increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of IL12A mRNA CTD PMID:15973123 NCBI chr 2:152,965,769...152,973,035
Ensembl chr 2:152,965,769...152,972,734 		JBrowse link
G Il12b interleukin 12B decreases response to substance
multiple interactions
increases expression		 ISO
EXP		 IL12B protein results in decreased susceptibility to Trinitrobenzenesulfonic Acid
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL12B mRNA]; Dexamethasone inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL12B mRNA]
icilin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL12B protein]
Trinitrobenzenesulfonic Acid results in increased expression of IL12B mRNA; Trinitrobenzenesulfonic Acid results in increased expression of IL12B protein		 CTD PMID:11782017 PMID:16867261 PMID:17375199 PMID:23596210 NCBI chr10:28,888,832...28,903,802
Ensembl chr10:28,893,008...28,902,903 		JBrowse link
G Il15 interleukin 15 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of IL15 protein CTD PMID:23596210 NCBI chr19:25,640,025...25,706,818
Ensembl chr19:25,640,251...25,706,820 		JBrowse link
G Il17a interleukin 17A increases expression
multiple interactions		 ISO
EXP		 Trinitrobenzenesulfonic Acid results in increased expression of IL17A mRNA; Trinitrobenzenesulfonic Acid results in increased expression of IL17A protein
[Trinitrobenzenesulfonic Acid results in increased susceptibility to [Ionomycin co-treated with Tetradecanoylphorbol Acetate]] which results in increased expression of IL17A protein
Methylene Blue inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL17A protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL17A protein]		 CTD PMID:17375199 PMID:23027085 PMID:27783946 PMID:31428839 NCBI chr 9:23,144,402...23,147,889
Ensembl chr 9:23,144,402...23,147,889 		JBrowse link
G Il18 interleukin 18 increases expression
multiple interactions		 ISO
EXP		 Trinitrobenzenesulfonic Acid results in increased expression of IL18 mRNA
Trinitrobenzenesulfonic Acid results in increased expression of IL18 protein
bergenin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL18 protein]		 CTD PMID:15973123 PMID:30365937 NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887 		JBrowse link
G Il1a interleukin 1 alpha increases expression
multiple interactions		 ISO Trinitrobenzenesulfonic Acid results in increased expression of IL1A mRNA
Trinitrobenzenesulfonic Acid results in increased expression of IL1A protein
icilin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1A protein]		 CTD PMID:12781210 PMID:23596210 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822 		JBrowse link
G Il1b interleukin 1 beta multiple interactions
increases expression		 ISO
EXP		 Anisomycin inhibits the reaction [TES protein inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]]; Anisomycin inhibits the reaction [TES protein inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]]; Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]; Dexamethasone inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]; Huangqin-Tang inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]; lancemaside A inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]; soyasaponin Ab inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]; soyasaponin I inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]; TES protein inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]; TES protein inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]
4-methylesculetin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]; [allicin co-treated with Mesalamine] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]; [allicin co-treated with Mesalamine] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]; [allicin co-treated with Sulfasalazine] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]; [allicin co-treated with Sulfasalazine] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]; [Inosine Monophosphate co-treated with potassium oxonate] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]; Active Hexose Correlated Compound inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]; Alendronate inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]; allicin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]; allicin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]; Ampicillin inhibits the reaction [Aspirin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]]; Ampicillin inhibits the reaction [Aspirin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]]; Ampicillin inhibits the reaction [Celecoxib promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]]; Ampicillin inhibits the reaction [Celecoxib promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]]; Aspirin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]; Aspirin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]; bergenin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]; Celecoxib promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]; Celecoxib promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]; Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]; Dexamethasone inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]; Dinoprostone analog inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]; geraniol inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]; Inosine Monophosphate inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]; kappa-casein glycomacropeptide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]; Mesalamine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]; Mesalamine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]; nitroaspirin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]; oxymatrine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]; oxymatrine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]; potassium oxonate inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]; Prednisolone inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]; SC 560 promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]; SCH 442416 inhibits the reaction [Inosine Monophosphate inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]; Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]; Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]
Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA; Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein		 CTD PMID:15140218 PMID:15604057 PMID:15793857 PMID:15867298 PMID:15973123 More... NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il1r1 interleukin 1 receptor type 1 multiple interactions
increases expression		 EXP Active Hexose Correlated Compound inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1R1 mRNA]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1R1 mRNA] CTD PMID:17449585 NCBI chr 9:42,504,917...42,580,958
Ensembl chr 9:42,504,735...42,579,937 		JBrowse link
G Il1rl1 interleukin 1 receptor-like 1 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of IL1RL1 mRNA CTD PMID:17982090 NCBI chr 9:42,661,694...42,727,266
Ensembl chr 9:42,697,192...42,727,256 		JBrowse link
G Il1rn interleukin 1 receptor antagonist multiple interactions
increases expression		 EXP Alendronate inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1RN mRNA]; kappa-casein glycomacropeptide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1RN mRNA]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1RN mRNA] CTD PMID:15867298 PMID:17375077 NCBI chr 3:7,111,567...7,127,451
Ensembl chr 3:7,111,550...7,127,445 		JBrowse link
G Il2 interleukin 2 multiple interactions
increases expression		 ISO seryl-leucyl-isoleucyl-glycyl--arginyl-leucinamide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL2 mRNA] CTD PMID:11717450 PMID:27783946 NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566 		JBrowse link
G Il23a interleukin 23 subunit alpha increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of IL23A mRNA CTD PMID:17375199 NCBI chr 7:721,809...723,923
Ensembl chr 7:721,809...723,923 		JBrowse link
G Il4 interleukin 4 increases expression
multiple interactions
decreases expression
decreases secretion		 ISO
EXP		 Trinitrobenzenesulfonic Acid results in increased expression of IL4 mRNA
[allicin co-treated with Mesalamine] inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased secretion of IL4 protein]; Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of IL4 mRNA]; Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of IL4 protein]; Dexamethasone inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of IL4 mRNA]; Dexamethasone inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of IL4 protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased secretion of IL4 protein]
Trinitrobenzenesulfonic Acid results in decreased expression of IL4 mRNA; Trinitrobenzenesulfonic Acid results in decreased expression of IL4 protein		 CTD PMID:15973123 PMID:16782535 PMID:16867261 PMID:25729217 PMID:27783946 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750 		JBrowse link
G Il6 interleukin 6 multiple interactions
increases expression
decreases expression		 ISO
EXP		 Anisomycin inhibits the reaction [TES protein inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 mRNA]]; Anisomycin inhibits the reaction [TES protein inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 protein]]; Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 mRNA]; Huangqin-Tang inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 mRNA]; icilin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 protein]; lancemaside A inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 protein]; notoginsenoside R1 inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 protein]; soyasaponin Ab inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 protein]; soyasaponin I inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 mRNA]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 protein]; TES protein inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 mRNA]; TES protein inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 protein]
Trinitrobenzenesulfonic Acid results in increased expression of IL6; Trinitrobenzenesulfonic Acid results in increased expression of IL6 mRNA; Trinitrobenzenesulfonic Acid results in increased expression of IL6 protein
Chalcones inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 mRNA]; Chalcones inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 protein]; cinnamaldehyde inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 protein]; hesperetin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 protein]; Hydroxamic Acids analog promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 mRNA]; Iridoid Glycosides inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 mRNA]; Methylene Blue inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 protein]; oxymatrine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 mRNA]; oxymatrine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 mRNA]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 protein]; Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 mRNA]
Trinitrobenzenesulfonic Acid results in decreased expression of IL6 mRNA		 CTD PMID:17375199 PMID:18079364 PMID:18200517 PMID:19956958 PMID:19998380 More... NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Insl3 insulin-like 3 decreases expression EXP Trinitrobenzenesulfonic Acid results in decreased expression of INSL3 mRNA CTD PMID:23537331 NCBI chr16:18,398,682...18,400,566
Ensembl chr16:18,384,829...18,400,560 		JBrowse link
G Irf1 interferon regulatory factor 1 decreases response to substance ISO IRF1 protein results in decreased susceptibility to Trinitrobenzenesulfonic Acid CTD PMID:21097874 NCBI chr10:37,917,155...37,924,166
Ensembl chr10:37,916,670...37,924,166 		JBrowse link
G Isg15 ISG15 ubiquitin-like modifier increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of ISG15 mRNA CTD PMID:17982090 NCBI chr 5:166,784,148...166,785,435
Ensembl chr 5:166,784,148...166,785,435 		JBrowse link
G Itm2a integral membrane protein 2A multiple interactions
increases expression		 ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of ITM2A mRNA] CTD PMID:18200517 NCBI chr  X:72,486,383...72,492,344
Ensembl chr  X:72,486,381...72,492,363 		JBrowse link
G Itpr2 inositol 1,4,5-trisphosphate receptor, type 2 increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of ITPR2 mRNA CTD PMID:23537331 NCBI chr 4:179,028,594...179,434,657
Ensembl chr 4:179,027,281...179,404,164 		JBrowse link
G Jak2 Janus kinase 2 increases phosphorylation
multiple interactions		 EXP Trinitrobenzenesulfonic Acid results in increased phosphorylation of JAK2 protein
cinnamaldehyde inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased phosphorylation of JAK2 protein]; hesperetin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased phosphorylation of JAK2 protein]		 CTD PMID:33522063 NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189 		JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO D-JNKI-1 inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of and results in increased phosphorylation of JUN protein]; Trinitrobenzenesulfonic Acid results in increased expression of and results in increased phosphorylation of JUN protein CTD PMID:22427801 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656 		JBrowse link
G Kcnab1 potassium voltage-gated channel subfamily A regulatory beta subunit 1 increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of KCNAB1 mRNA CTD PMID:23537331 NCBI chr 2:149,137,025...149,603,540
Ensembl chr 2:149,137,041...149,603,534 		JBrowse link
G Kcnj4 potassium inwardly-rectifying channel, subfamily J, member 4 decreases expression EXP Trinitrobenzenesulfonic Acid results in decreased expression of KCNJ4 mRNA CTD PMID:23537331 NCBI chr 7:111,047,097...111,074,151
Ensembl chr 7:111,047,094...111,074,151 		JBrowse link
G Kcnq4 potassium voltage-gated channel subfamily Q member 4 increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of KCNQ4 mRNA CTD PMID:23537331 NCBI chr 5:134,275,145...134,326,992
Ensembl chr 5:134,275,934...134,326,932 		JBrowse link
G Kctd9 potassium channel tetramerization domain containing 9 increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of KCTD9 mRNA CTD PMID:23537331 NCBI chr15:41,942,165...41,969,862
Ensembl chr15:41,942,381...41,969,862 		JBrowse link
G Kitlg KIT ligand increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of KITLG mRNA CTD PMID:17385238 NCBI chr 7:34,896,075...34,977,215
Ensembl chr 7:34,896,053...34,977,214 		JBrowse link
G Kl Klotho multiple interactions
decreases expression		 ISO KL protein inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of TRPV5 protein]
Trinitrobenzenesulfonic Acid results in decreased expression of KL protein		 CTD PMID:23747339 NCBI chr12:490,402...531,417
Ensembl chr12:490,399...530,080 		JBrowse link
G L1cam L1 cell adhesion molecule increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of L1CAM mRNA CTD PMID:17982090 NCBI chr  X:151,597,270...151,623,776
Ensembl chr  X:151,597,277...151,623,857 		JBrowse link
G Lama3 laminin subunit alpha 3 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of LAMA3 mRNA CTD PMID:17982090 NCBI chr18:3,523,168...3,751,722
Ensembl chr18:3,523,133...3,751,353 		JBrowse link
G Lbp lipopolysaccharide binding protein multiple interactions
increases expression		 ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of LBP mRNA] CTD PMID:18200517 NCBI chr 3:146,953,889...146,981,032
Ensembl chr 3:146,954,015...146,981,586 		JBrowse link
G Lcn2 lipocalin 2 multiple interactions
increases expression		 ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of LCN2 mRNA] CTD PMID:17982090 PMID:18200517 NCBI chr 3:15,680,688...15,684,033
Ensembl chr 3:15,680,687...15,684,095 		JBrowse link
G Lcp1 lymphocyte cytosolic protein 1 increases expression
multiple interactions		 ISO Trinitrobenzenesulfonic Acid results in increased expression of LCP1 mRNA
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of LCP1 mRNA]		 CTD PMID:18200517 NCBI chr15:50,443,300...50,544,682
Ensembl chr15:50,488,149...50,544,680 		JBrowse link
G Lgmn legumain multiple interactions
increases expression		 ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of LGMN mRNA] CTD PMID:18200517 NCBI chr 6:121,544,048...121,582,495
Ensembl chr 6:121,544,053...121,582,480 		JBrowse link
G Lilrb4 leukocyte immunoglobulin like receptor B4 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of LILRB4 mRNA CTD PMID:17982090 NCBI chr 1:69,805,020...69,810,628
Ensembl chr 1:69,805,250...69,810,660 		JBrowse link
G Lox lysyl oxidase multiple interactions
increases expression		 ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of LOX mRNA] CTD PMID:17982090 PMID:18200517 NCBI chr18:45,964,544...45,977,431
Ensembl chr18:45,967,343...46,041,477 		JBrowse link
G Lrg1 leucine-rich alpha-2-glycoprotein 1 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of LRG1 mRNA CTD PMID:17982090 NCBI chr 9:947,516...949,773
Ensembl chr 9:947,516...949,813 		JBrowse link
G Lst1 leukocyte specific transcript 1 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of LST1 mRNA CTD PMID:17982090 NCBI chr20:3,634,680...3,639,731
Ensembl chr20:3,634,749...3,637,997 		JBrowse link
G Lum lumican increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of LUM mRNA CTD PMID:17982090 NCBI chr 7:32,358,990...32,365,794
Ensembl chr 7:32,358,614...32,365,793 		JBrowse link
G Ly6a lymphocyte antigen 6 family member A increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of LY6A mRNA CTD PMID:17982090 NCBI chr 7:107,177,191...107,189,436
Ensembl chr 7:107,183,469...107,189,981 		JBrowse link
G Ly86 lymphocyte antigen 86 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of LY86 mRNA CTD PMID:17982090 NCBI chr17:27,415,807...27,499,695
Ensembl chr17:27,415,830...27,487,260 		JBrowse link
G Lyz2 lysozyme 2 multiple interactions
increases expression		 ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of LYZ mRNA] CTD PMID:17982090 PMID:18200517 NCBI chr 7:52,906,810...52,912,154
Ensembl chr 7:52,906,811...52,912,106 		JBrowse link
G Madcam1 mucosal vascular addressin cell adhesion molecule 1 multiple interactions
increases expression		 ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MADCAM1 mRNA] CTD PMID:18200517 NCBI chr 7:10,036,301...10,039,703
Ensembl chr 7:10,036,301...10,039,703 		JBrowse link
G Maf MAF bZIP transcription factor increases expression
multiple interactions		 ISO Trinitrobenzenesulfonic Acid results in increased expression of MAF mRNA; Trinitrobenzenesulfonic Acid results in increased expression of MAF protein
sinomenine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MAF mRNA]; sinomenine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MAF protein]		 CTD PMID:24066068 NCBI chr19:43,353,867...43,713,162
Ensembl chr19:43,360,342...43,712,365 		JBrowse link
G Manf mesencephalic astrocyte-derived neurotrophic factor increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of MANF mRNA CTD PMID:17982090 NCBI chr 8:107,500,856...107,551,595
Ensembl chr 8:107,548,352...107,551,438 		JBrowse link
G Maoa monoamine oxidase A multiple interactions
decreases expression		 ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of MAOA mRNA] CTD PMID:18200517 NCBI chr  X:6,032,172...6,098,308
Ensembl chr  X:6,030,795...6,099,593 		JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta multiple interactions
increases lipidation		 EXP Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased lipidation of MAP1LC3B protein] CTD PMID:30503585 NCBI chr19:49,665,795...49,673,655
Ensembl chr19:49,665,791...49,677,690
Ensembl chr16:49,665,791...49,677,690 		JBrowse link
G Map3k6 mitogen-activated protein kinase kinase kinase 6 decreases expression EXP Trinitrobenzenesulfonic Acid results in decreased expression of MAP3K6 mRNA CTD PMID:23537331 NCBI chr 5:145,440,126...145,452,213
Ensembl chr 5:145,440,346...145,452,212 		JBrowse link
G Mapk6 mitogen-activated protein kinase 6 increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of MAPK6 mRNA CTD PMID:23537331 NCBI chr 8:76,146,650...76,169,767
Ensembl chr 8:76,146,690...76,169,720 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 increases expression
multiple interactions
increases phosphorylation		 EXP
ISO		 Trinitrobenzenesulfonic Acid results in increased expression of MAPK8 mRNA
TES protein inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased phosphorylation of MAPK8 protein]		 CTD PMID:23537331 PMID:39237074 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981 		JBrowse link
G Mapk9 mitogen-activated protein kinase 9 multiple interactions
increases expression		 ISO [Trinitrobenzenesulfonic Acid results in increased expression of MAPK9 protein] promotes the reaction [BCL2L11 protein binds to MAPK9 protein]; D-JNKI-1 inhibits the reaction [[Trinitrobenzenesulfonic Acid results in increased expression of MAPK9 protein] promotes the reaction [BCL2L11 protein binds to MAPK9 protein]]; D-JNKI-1 inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MAPK9 protein] CTD PMID:22427801 NCBI chr10:34,169,661...34,211,138
Ensembl chr10:34,169,675...34,210,178 		JBrowse link
G Marcksl1 MARCKS-like 1 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of MARCKSL1 mRNA CTD PMID:17982090 NCBI chr 5:141,851,491...141,853,814
Ensembl chr 5:141,850,110...141,853,817 		JBrowse link
G Me1 malic enzyme 1 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of ME1 mRNA CTD PMID:17982090 NCBI chr 8:87,549,043...87,660,251
Ensembl chr 8:87,549,043...87,660,304 		JBrowse link
G Mgp matrix Gla protein increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of MGP mRNA CTD PMID:17982090 NCBI chr 4:169,766,290...169,769,612
Ensembl chr 4:169,766,279...169,769,667 		JBrowse link
G Mir155 microRNA 155 increases expression
multiple interactions		 ISO Trinitrobenzenesulfonic Acid results in increased expression of MIR155 mRNA
sinomenine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MIR155 mRNA]		 CTD PMID:24066068 NCBI chr11:23,774,654...23,774,718
Ensembl chr11:23,774,654...23,774,718 		JBrowse link
G Mir29a microRNA 29a increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of MIR29A mRNA CTD PMID:25277410 NCBI chr 4:59,650,608...59,650,695 JBrowse link
G Mir29b1 microRNA 29b-1 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of MIR29B-1 mRNA CTD PMID:25277410 NCBI chr 4:59,650,987...59,651,067
Ensembl chr 4:59,650,986...59,651,067 		JBrowse link
G Mki67 marker of proliferation Ki-67 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of MKI67 mRNA CTD PMID:17982090 NCBI chr 1:190,496,319...190,522,983
Ensembl chr 1:190,496,319...190,522,762 		JBrowse link
G Mmp1 matrix metallopeptidase 1 multiple interactions
increases expression		 EXP ilomastat affects the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MMP1 protein]; ilomastat inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MMP1 mRNA]
Trinitrobenzenesulfonic Acid results in increased expression of MMP1 mRNA; Trinitrobenzenesulfonic Acid results in increased expression of MMP1 protein		 CTD PMID:18837084 NCBI chr 8:4,658,588...4,679,099
Ensembl chr 8:4,658,588...4,679,097 		JBrowse link
G Mmp12 matrix metallopeptidase 12 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of MMP12 mRNA CTD PMID:17982090 NCBI chr 8:4,581,785...4,591,687
Ensembl chr 8:4,581,785...4,599,611 		JBrowse link
G Mmp14 matrix metallopeptidase 14 multiple interactions
increases expression		 ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MMP14 mRNA] CTD PMID:18200517 NCBI chr15:27,887,795...27,897,020
Ensembl chr15:27,887,727...27,899,864 		JBrowse link
G Mmp15 matrix metallopeptidase 15 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of MMP15 mRNA CTD PMID:17982090 NCBI chr19:9,663,449...9,684,943
Ensembl chr19:9,663,449...9,684,943 		JBrowse link
G Mmp2 matrix metallopeptidase 2 multiple interactions
increases expression		 ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MMP2 mRNA] CTD PMID:18200517 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870 		JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions EXP 4-methylesculetin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of and results in increased cleavage of MMP9 protein]; Prednisolone inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of and results in increased cleavage of MMP9 protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of and results in increased cleavage of MMP9 protein]; Trinitrobenzenesulfonic Acid results in increased activity of and results in increased cleavage of MMP9 protein CTD PMID:22119283 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120 		JBrowse link
G Mnda myeloid cell nuclear differentiation antigen increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of IFI204 mRNA
Trinitrobenzenesulfonic Acid results in increased expression of MNDA mRNA		 CTD PMID:17982090 NCBI chr13:86,017,888...86,035,556
Ensembl chr13:86,017,892...86,034,201 		JBrowse link
G Moxd2 monooxygenase, DBH-like 2 decreases expression ISO Trinitrobenzenesulfonic Acid results in decreased expression of MOXD2 mRNA CTD PMID:17982090 NCBI chr 4:69,724,693...69,733,188
Ensembl chr 4:69,724,239...69,733,299 		JBrowse link
G Mpo myeloperoxidase multiple interactions
increases expression
increases activity		 EXP
ISO		 4-methylesculetin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; [potassium oxonate co-treated with Inosine Monophosphate] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Aspirin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; bergenin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Cadmium Chloride inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Celecoxib promotes the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Chalcones inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; cinnamaldehyde inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Ciprofloxacin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; dapagliflozin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Dexamethasone inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Dinoprostone analog inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Genistein inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; geraniol inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MPO protein]; Heme inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; hesperetin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Hydroxamic Acids analog promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MPO protein]; Indomethacin inhibits the reaction [Smoke promotes the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]]; Indomethacin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Inosine Monophosphate inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Iridoid Glycosides inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Isatin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MPO]; Mesalamine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Methylene Blue inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MPO protein]; montelukast inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; N-(3-(aminomethyl)benzyl)acetamidine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; nimesulide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; nitroaspirin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; potassium oxonate inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Prednisolone inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Resveratrol inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Rifampin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; SC 560 promotes the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; SCH 442416 inhibits the reaction [Inosine Monophosphate inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]]; Smoke promotes the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Spironolactone inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MPO protein]; Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MPO protein]; Telmisartan inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; tin protoporphyrin IX promotes the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; zileuton inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; zinc protoporphyrin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]
Trinitrobenzenesulfonic Acid results in increased expression of MPO; Trinitrobenzenesulfonic Acid results in increased expression of MPO protein
17-hydroxy-4,7,10,13,15,19-docosahexaenoic acid inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; 7,14-dihydroxydocosa-4,8,10,12,16,19-hexaenoic acid inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; 8-(bis(2-methylphenyl)methyl)-3-phenyl-8-azabicyclo(3.2.1)octan-3-ol inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; [cholan-2,3,24-tryl-2,3,24-trisulfate binds to and results in increased activity of NR1I2 protein] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MPO protein]; [Rifaximin binds to and results in increased activity of NR1I2 protein] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MPO protein]; cholan-2,3,24-tryl-2,3,24-trisulfate inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MPO protein]; ginsenoside Re inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Huangqin-Tang inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; icilin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; J 113397 inhibits the reaction [8-(bis(2-methylphenyl)methyl)-3-phenyl-8-azabicyclo(3.2.1)octan-3-ol inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]]; lancemaside A inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Mesalamine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; morphiceptin analog affects the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; notoginsenoside R1 inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Plant Extracts inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; resolvin D1 inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; resolvin D2 inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Rifaximin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MPO protein]; RN 1734 inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Ruthenium Red inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; sinomenine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; stattic inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]
2,4,6-trinitrobenzenesulfonic acid increases myeloperoxidase enzyme activity in rat colon		 CTD
RGD		 PMID:10845656 PMID:10877837 PMID:11137876 PMID:11504810 PMID:11668029 More... RGD:152995414 NCBI chr10:72,594,883...72,608,862
Ensembl chr10:72,594,661...72,604,819 		JBrowse link
G Mrc1 mannose receptor, C type 1 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of MRC1 mRNA CTD PMID:17982090 NCBI chr17:77,249,187...77,330,857
Ensembl chr17:77,249,187...77,330,857 		JBrowse link
G Mrm3 mitochondrial rRNA methyltransferase 3 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of MRM3 mRNA CTD PMID:17982090 NCBI chr10:61,095,920...61,125,421
Ensembl chr10:61,095,952...61,102,630 		JBrowse link
G Mrpl47 mitochondrial ribosomal protein L47 multiple interactions
decreases expression		 ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of MRPL47 mRNA] CTD PMID:18200517 NCBI chr 2:115,507,842...115,520,093
Ensembl chr 2:115,500,264...115,518,994 		JBrowse link
G Msn moesin multiple interactions
increases expression		 ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MSN mRNA] CTD PMID:18200517 NCBI chr  X:60,996,043...61,064,011
Ensembl chr  X:60,995,951...61,065,628 		JBrowse link
G Mtor mechanistic target of rapamycin kinase increases phosphorylation
multiple interactions		 EXP Trinitrobenzenesulfonic Acid results in increased phosphorylation of MTOR protein
dapagliflozin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased phosphorylation of MTOR protein]; Mesalamine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased phosphorylation of MTOR protein]		 CTD PMID:33412153 NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311 		JBrowse link
G Muc17 mucin 17, cell surface associated increases expression
multiple interactions
decreases expression		 EXP Trinitrobenzenesulfonic Acid results in increased expression of MUC3 mRNA
Active Hexose Correlated Compound inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MUC3 mRNA]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MUC3 mRNA]
Trinitrobenzenesulfonic Acid results in decreased expression of MUC3 mRNA		 CTD PMID:17375077 PMID:17449585 NCBI chr12:19,527,251...19,536,924
Ensembl chr12:19,527,321...19,538,522 		JBrowse link
G Muc2 mucin 2, oligomeric mucus/gel-forming multiple interactions
increases expression
decreases expression		 EXP
ISO		 Active Hexose Correlated Compound inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MUC2 mRNA]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MUC2 mRNA]
Trinitrobenzenesulfonic Acid results in decreased expression of MUC2 mRNA		 CTD PMID:17449585 PMID:19998380 PMID:25307695 NCBI chr 1:196,799,494...196,831,740
Ensembl chr 1:196,799,517...196,831,756 		JBrowse link
G Muc4 mucin 4, cell surface associated multiple interactions
increases expression		 EXP Active Hexose Correlated Compound inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MUC4 mRNA]; kappa-casein glycomacropeptide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MUC4 mRNA]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MUC4 mRNA] CTD PMID:15867298 PMID:17449585 NCBI chr11:68,008,245...68,053,242 JBrowse link
G Myd88 MYD88, innate immune signal transduction adaptor multiple interactions
increases expression		 EXP Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MYD88 protein]; oxymatrine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MYD88 protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MYD88 protein]
Trinitrobenzenesulfonic Acid results in increased expression of MYD88; Trinitrobenzenesulfonic Acid results in increased expression of MYD88 protein		 CTD PMID:16891783 PMID:19002562 PMID:35290143 NCBI chr 8:119,074,439...119,078,508
Ensembl chr 8:119,074,437...119,079,415 		JBrowse link
G Naglu N-acetyl-alpha-glucosaminidase increases secretion EXP Trinitrobenzenesulfonic Acid results in increased secretion of NAGLU protein CTD PMID:23307618 NCBI chr10:86,001,545...86,009,049
Ensembl chr10:86,001,566...86,008,972 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 multiple interactions
decreases expression
affects expression		 EXP 4-methylesculetin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of NFE2L2 mRNA]; dapagliflozin inhibits the reaction [Trinitrobenzenesulfonic Acid affects the expression of NFE2L2 protein]; Mesalamine inhibits the reaction [Trinitrobenzenesulfonic Acid affects the expression of NFE2L2 protein]; Methylene Blue inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of NFE2L2 mRNA]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of NFE2L2 mRNA] CTD PMID:31428839 PMID:31669340 PMID:33412153 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737 		JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 increases expression
multiple interactions		 EXP Trinitrobenzenesulfonic Acid results in increased expression of NFKB1 protein
geraniol inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of NFKB1 protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of NFKB1 protein]		 CTD PMID:26165751 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404 		JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions
increases degradation
decreases expression		 EXP bergenin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of NFKBIA protein]; Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased degradation of NFKBIA protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased degradation of NFKBIA protein] CTD PMID:15793857 PMID:30365937 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941 		JBrowse link
G Ngf nerve growth factor increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of NGF mRNA CTD PMID:17385238 NCBI chr 2:189,901,058...189,954,452
Ensembl chr 2:189,901,058...189,954,452 		JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 multiple interactions
increases expression		 EXP bergenin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of NLRP3 protein] CTD PMID:30365937 NCBI chr10:44,326,770...44,353,814
Ensembl chr10:44,328,566...44,352,811 		JBrowse link
G Nmt2 N-myristoyltransferase 2 decreases expression
multiple interactions		 ISO Trinitrobenzenesulfonic Acid results in decreased expression of NMT2 mRNA
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of NMT2 mRNA]		 CTD PMID:18200517 NCBI chr17:74,917,833...74,964,788
Ensembl chr17:74,917,833...74,961,080 		JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 increases expression ISO
EXP		 Trinitrobenzenesulfonic Acid results in increased expression of NOD2 mRNA; Trinitrobenzenesulfonic Acid results in increased expression of NOD2 protein CTD PMID:16891783 PMID:22147983 NCBI chr19:18,382,369...18,422,817
Ensembl chr19:18,382,439...18,417,177 		JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions
increases expression
affects response to substance
increases activity		 ISO
EXP		 Minocycline inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of NOS2 mRNA]; NOS2 gene mutant form inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CCN4 mRNA]; seryl-leucyl-isoleucyl-glycyl--arginyl-leucinamide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of NOS2 mRNA]; soyasaponin I inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of NOS2 protein]
Trinitrobenzenesulfonic Acid results in increased expression of NOS2 mRNA; Trinitrobenzenesulfonic Acid results in increased expression of NOS2 protein
Alendronate affects the reaction [Trinitrobenzenesulfonic Acid results in increased expression of NOS2 protein]; Ampicillin inhibits the reaction [Aspirin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of NOS2 mRNA]]; Ampicillin inhibits the reaction [Celecoxib promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of NOS2 mRNA]]; Aspirin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of NOS2 mRNA]; bergenin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of NOS2 protein]; Celecoxib promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of NOS2 mRNA]; Hydroxamic Acids analog promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of NOS2 mRNA]; kappa-casein glycomacropeptide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of NOS2 protein]; Methylene Blue inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of NOS2 protein]; montelukast inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of NOS2 protein]; nitroaspirin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of NOS2 mRNA]; Sulfasalazine affects the reaction [Trinitrobenzenesulfonic Acid results in increased expression of NOS2 protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of NOS2 protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of NOS2 protein]; Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of NOS2 mRNA]; Telmisartan inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of NOS2 mRNA]
NOS2 protein affects the susceptibility to Trinitrobenzenesulfonic Acid		 CTD PMID:10845656 PMID:11504810 PMID:11698051 PMID:11717450 PMID:15867298 More... NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210 		JBrowse link
G Npy1r neuropeptide Y receptor Y1 increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of NPY1R mRNA CTD PMID:23537331 NCBI chr16:23,037,788...23,047,330
Ensembl chr16:23,037,789...23,046,759 		JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of NQO1 mRNA CTD PMID:19524605 PMID:22609641 PMID:25724174 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557 		JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 decreases expression ISO Trinitrobenzenesulfonic Acid results in decreased expression of NR1H4 mRNA; Trinitrobenzenesulfonic Acid results in decreased expression of NR1H4 protein CTD PMID:21829567 NCBI chr 7:23,846,122...23,942,085
Ensembl chr 7:23,846,122...23,942,047 		JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 decreases expression
multiple interactions		 ISO Trinitrobenzenesulfonic Acid results in decreased expression of NR1I2 mRNA
[cholan-2,3,24-tryl-2,3,24-trisulfate binds to and results in increased activity of NR1I2 protein] which results in decreased susceptibility to Trinitrobenzenesulfonic Acid; [Rifaximin binds to and results in increased activity of NR1I2 protein] which results in decreased susceptibility to Trinitrobenzenesulfonic Acid
[cholan-2,3,24-tryl-2,3,24-trisulfate binds to and results in increased activity of NR1I2 protein] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CCL3 protein]; [cholan-2,3,24-tryl-2,3,24-trisulfate binds to and results in increased activity of NR1I2 protein] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IFNG protein]; [cholan-2,3,24-tryl-2,3,24-trisulfate binds to and results in increased activity of NR1I2 protein] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MPO protein]; [cholan-2,3,24-tryl-2,3,24-trisulfate binds to and results in increased activity of NR1I2 protein] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; [rifaximin binds to and results in increased activity of NR1I2 protein] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CCL3 protein]; [rifaximin binds to and results in increased activity of NR1I2 protein] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IFNG protein]; [rifaximin binds to and results in increased activity of NR1I2 protein] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MPO protein]; [rifaximin binds to and results in increased activity of NR1I2 protein] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]		 CTD PMID:21599020 PMID:21829567 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658 		JBrowse link
G Nr2f1 nuclear receptor subfamily 2, group F, member 1 increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of NR2F1 mRNA CTD PMID:23537331 NCBI chr 2:8,040,375...8,050,123
Ensembl chr 2:8,040,377...8,050,123 		JBrowse link
G Nts neurotensin multiple interactions ISO NTS protein promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of VWF protein] CTD PMID:25307345 NCBI chr 7:37,564,944...37,574,350
Ensembl chr 7:37,564,533...37,574,423 		JBrowse link
G Ntsr1 neurotensin receptor 1 multiple interactions
increases response to substance		 ISO NTSR1 protein affects the reaction [Trinitrobenzenesulfonic Acid results in increased expression of VEGFA mRNA]
NTSR1 protein results in increased susceptibility to Trinitrobenzenesulfonic Acid		 CTD PMID:25307345 NCBI chr 3:167,606,215...167,656,371
Ensembl chr 3:167,606,215...167,656,377 		JBrowse link
G Nucb2 nucleobindin 2 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of NUCB2 mRNA CTD PMID:17982090 NCBI chr 1:170,750,830...170,787,356
Ensembl chr 1:170,750,877...170,787,353 		JBrowse link
G Ocln occludin multiple interactions
decreases expression		 ISO
EXP		 Dexamethasone inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of OCLN mRNA]; ginsenoside Re inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of OCLN protein]
Trinitrobenzenesulfonic Acid results in decreased expression of OCLN mRNA; Trinitrobenzenesulfonic Acid results in decreased expression of OCLN protein
oxymatrine inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of OCLN mRNA]; oxymatrine inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of OCLN protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of OCLN mRNA]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of OCLN protein]		 CTD PMID:22147983 PMID:22849695 PMID:25307695 PMID:35290143 NCBI chr 2:31,657,217...31,707,466
Ensembl chr 2:31,657,220...31,764,150 		JBrowse link
G Odc1 ornithine decarboxylase 1 decreases expression EXP Trinitrobenzenesulfonic Acid results in decreased expression of ODC1 mRNA CTD PMID:12163651 NCBI chr 6:40,329,831...40,336,444
Ensembl chr 6:40,329,964...40,336,440 		JBrowse link
G Oprd1 opioid receptor, delta 1 multiple interactions
increases expression		 EXP Mesalamine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of OPRD1 mRNA]; Mesalamine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of OPRD1 protein]; qingre zaoshi liangxue fang inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of OPRD1 mRNA]; qingre zaoshi liangxue fang inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of OPRD1 protein]
Trinitrobenzenesulfonic Acid results in increased expression of OPRD1 mRNA; Trinitrobenzenesulfonic Acid results in increased expression of OPRD1 protein		 CTD PMID:24637189 NCBI chr 5:144,306,188...144,340,960
Ensembl chr 5:144,306,188...144,340,960 		JBrowse link
G Oprl1 opioid related nociceptin receptor 1 increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of OPRL1 mRNA CTD PMID:23537331 NCBI chr 3:168,831,934...168,839,920
Ensembl chr 3:168,834,003...168,839,920 		JBrowse link
G Or2h1 olfactory receptor family 2 subfamily H member 1 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of OR2H1 mRNA CTD PMID:17982090 NCBI chr20:1,445,980...1,446,918
Ensembl chr20:1,444,837...1,449,341 		JBrowse link
G Or2h2c olfactory receptor family 2 subfamily H member 2C increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of OR2H2 mRNA CTD PMID:17982090 NCBI chr20:1,398,964...1,399,902
Ensembl chr20:1,395,108...1,400,441 		JBrowse link
G Osmr oncostatin M receptor multiple interactions
increases expression		 ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of OSMR mRNA] CTD PMID:17982090 PMID:18200517 NCBI chr 2:55,907,119...55,961,373
Ensembl chr 2:55,907,132...55,961,262 		JBrowse link
G Otud4 OTU deubiquitinase 4 decreases expression ISO Trinitrobenzenesulfonic Acid results in decreased expression of OTUD4 mRNA CTD PMID:17982090 NCBI chr19:28,236,713...28,279,815
Ensembl chr19:28,236,713...28,279,815 		JBrowse link
G P2rx7 purinergic receptor P2X 7 increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of P2RX7 mRNA CTD PMID:23537331 NCBI chr12:33,889,709...33,934,168
Ensembl chr12:33,879,745...33,934,619 		JBrowse link
G P2ry1 purinergic receptor P2Y1 increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of P2RY1 mRNA CTD PMID:23537331 NCBI chr 2:145,241,975...145,248,186
Ensembl chr 2:145,241,849...145,248,457 		JBrowse link
G P2ry13 purinergic receptor P2Y13 increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of P2RY13 mRNA CTD PMID:23537331 NCBI chr 2:143,470,437...143,476,360
Ensembl chr 2:143,470,425...143,473,434 		JBrowse link
G Pak2 p21 (RAC1) activated kinase 2 increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of PAK2 mRNA CTD PMID:23537331 NCBI chr11:68,707,940...68,768,816
Ensembl chr11:68,707,969...68,768,816 		JBrowse link
G Pck1 phosphoenolpyruvate carboxykinase 1 decreases expression ISO Trinitrobenzenesulfonic Acid results in decreased expression of PCK1 mRNA CTD PMID:17982090 NCBI chr 3:161,930,256...161,936,205
Ensembl chr 3:161,930,256...161,936,191 		JBrowse link
G Pcna proliferating cell nuclear antigen increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of PCNA mRNA; Trinitrobenzenesulfonic Acid results in increased expression of PCNA protein CTD PMID:19234664 NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995 		JBrowse link
G Pdia3 protein disulfide isomerase family A, member 3 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of PDIA3 mRNA CTD PMID:17982090 NCBI chr 3:108,388,189...108,412,013
Ensembl chr 3:108,388,245...108,413,236 		JBrowse link
G Pdpn podoplanin multiple interactions
increases expression		 ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PDPN mRNA] CTD PMID:18200517 NCBI chr 5:155,601,691...155,635,656
Ensembl chr 5:155,601,691...155,635,656 		JBrowse link
G Pecam1 platelet and endothelial cell adhesion molecule 1 increases expression
multiple interactions		 EXP Trinitrobenzenesulfonic Acid results in increased expression of PECAM1 protein
Chalcones inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PECAM1 protein]		 CTD PMID:22410118 NCBI chr10:91,590,521...91,652,279
Ensembl chr10:91,590,521...91,652,116 		JBrowse link
G Pgs1 phosphatidylglycerophosphate synthase 1 multiple interactions
increases expression		 ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PGS1 mRNA] CTD PMID:18200517 NCBI chr10:103,214,635...103,250,254
Ensembl chr10:103,214,646...103,250,254 		JBrowse link
G Pir pirin increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of PIR mRNA CTD PMID:19524605 PMID:22609641 NCBI chr  X:30,108,536...30,219,269
Ensembl chr  X:30,108,538...30,219,218 		JBrowse link
G Pirb paired Ig-like receptor B multiple interactions
increases expression		 ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of LILRB3 mRNA] CTD PMID:18200517 NCBI chr 1:65,499,195...65,506,666
Ensembl chr 1:65,499,195...65,506,666 		JBrowse link
G Pklr pyruvate kinase L/R increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of PKLR mRNA CTD PMID:17982090 NCBI chr 2:174,543,008...174,551,863
Ensembl chr 2:174,543,039...174,551,870 		JBrowse link
G Pla2g12a phospholipase A2, group XIIA increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of PLA2G12A mRNA CTD PMID:17982090 NCBI chr 2:218,436,497...218,452,742
Ensembl chr 2:218,436,513...218,452,740 		JBrowse link
G Pla2g2a phospholipase A2 group IIA multiple interactions
increases expression		 ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PLA2G2A mRNA] CTD PMID:17982090 PMID:18200517 NCBI chr 5:151,076,442...151,079,019
Ensembl chr 5:151,076,442...151,079,014 		JBrowse link
G Pla2g7 phospholipase A2 group VII increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of PLA2G7 mRNA CTD PMID:17982090 NCBI chr 9:17,362,214...17,404,476
Ensembl chr 9:17,362,225...17,404,476 		JBrowse link
G Plod2 procollagen lysine, 2-oxoglutarate 5-dioxygenase 2 increases expression
multiple interactions		 ISO Trinitrobenzenesulfonic Acid results in increased expression of PLOD2 mRNA
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PLOD2 mRNA]		 CTD PMID:18200517 NCBI chr 8:93,084,548...93,167,255
Ensembl chr 8:93,084,513...93,167,255 		JBrowse link
G Pnliprp1 pancreatic lipase-related protein 1 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of PNLIPRP1 mRNA CTD PMID:17982090 NCBI chr 1:257,867,885...257,883,514
Ensembl chr 1:257,867,885...257,883,514 		JBrowse link
G Pomc proopiomelanocortin decreases expression
increases expression		 ISO
EXP		 Trinitrobenzenesulfonic Acid results in decreased expression of POMC mRNA
Trinitrobenzenesulfonic Acid results in increased expression of POMC protein		 CTD PMID:11959675 PMID:25307695 NCBI chr 6:26,939,844...26,945,666
Ensembl chr 6:26,939,837...26,945,664 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma multiple interactions
decreases expression		 EXP
ISO		 Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of PPARG mRNA]; Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of PPARG protein]; Dexamethasone inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of PPARG mRNA]; Dexamethasone inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of PPARG protein]; geraniol inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of PPARG mRNA]; geraniol inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of PPARG protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of PPARG mRNA]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of PPARG protein]; Telmisartan inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of PPARG mRNA]
Trinitrobenzenesulfonic Acid results in decreased expression of PPARG mRNA; Trinitrobenzenesulfonic Acid results in decreased expression of PPARG protein		 CTD PMID:16782535 PMID:19617644 PMID:21829567 PMID:24831514 PMID:26165751 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468 		JBrowse link
G Prkci protein kinase C, iota increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of PRKCI mRNA CTD PMID:23537331 NCBI chr 2:112,321,919...112,382,305
Ensembl chr 2:112,321,929...112,382,352 		JBrowse link
G Prss1 serine protease 1 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of PRSS1 mRNA; Trinitrobenzenesulfonic Acid results in increased expression of TRY10 mRNA CTD PMID:17982090 NCBI chr 4:70,364,589...70,367,792
Ensembl chr 4:70,364,586...70,367,792 		JBrowse link
G Prss3 serine protease 3 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of PRSS3 mRNA CTD PMID:17982090 NCBI chr 4:70,203,088...70,206,562
Ensembl chr 4:70,203,088...70,206,562 		JBrowse link
G Psme3 proteasome activator subunit 3 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of PSME3 mRNA CTD PMID:17982090 NCBI chr10:86,257,672...86,265,458
Ensembl chr10:86,257,668...86,333,804 		JBrowse link
G Ptger2 prostaglandin E receptor 2 increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of PTGER2 mRNA CTD PMID:23537331 PMID:25526689 NCBI chr15:18,215,013...18,228,714
Ensembl chr15:18,217,285...18,228,714 		JBrowse link
G Ptger4 prostaglandin E receptor 4 decreases expression EXP Trinitrobenzenesulfonic Acid results in decreased expression of PTGER4 mRNA CTD PMID:25526689 NCBI chr 2:54,330,563...54,347,451
Ensembl chr 2:54,335,424...54,346,670 		JBrowse link
G Ptges prostaglandin E synthase increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of PTGES mRNA CTD PMID:25526689 NCBI chr 3:14,177,892...14,189,236 JBrowse link
G Ptgir prostaglandin I2 receptor increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of PTGIR mRNA CTD PMID:25526689 NCBI chr 1:77,579,596...77,581,979
Ensembl chr 1:77,579,596...77,581,979 		JBrowse link
G Ptgis prostaglandin I2 synthase increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of PTGIS mRNA CTD PMID:25526689 NCBI chr 3:155,928,564...155,964,228
Ensembl chr 3:155,916,412...155,965,451 		JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 decreases expression EXP Trinitrobenzenesulfonic Acid results in decreased expression of PTGS1 mRNA CTD PMID:25526689 NCBI chr 3:19,584,015...19,605,589
Ensembl chr 3:19,584,015...19,605,586 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions
increases expression
decreases expression		 ISO
EXP		 Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 mRNA]; Huangqin-Tang inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 protein]; lancemaside A inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 protein]; seryl-leucyl-isoleucyl-glycyl--arginyl-leucinamide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 mRNA]; soyasaponin I inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 protein]
Alendronate affects the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 protein]; Ampicillin inhibits the reaction [Aspirin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 mRNA]]; Ampicillin inhibits the reaction [Celecoxib promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 mRNA]]; Aspirin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 mRNA]; bergenin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 protein]; Celecoxib promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 mRNA]; Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 mRNA]; Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 protein]; Dexamethasone inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 mRNA]; Dexamethasone inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 protein]; Genistein inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 mRNA]; Genistein inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 protein]; Isatin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2]; nitroaspirin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 mRNA]; Resveratrol inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 protein]; Smoke promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 mRNA]; Smoke promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 protein]; Telmisartan inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 mRNA]
Trinitrobenzenesulfonic Acid results in increased expression of PTGS2; Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 mRNA; Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 protein
Trinitrobenzenesulfonic Acid results in decreased expression of PTGS2 mRNA		 CTD PMID:11137876 PMID:11698051 PMID:11717450 PMID:11820457 PMID:15973123 More... NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Ptprc protein tyrosine phosphatase, receptor type, C increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of PTPRC mRNA CTD PMID:17982090 NCBI chr13:49,596,193...49,708,283
Ensembl chr13:49,596,193...49,708,692 		JBrowse link
G Ptpro protein tyrosine phosphatase, receptor type, O multiple interactions
increases expression		 ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTPRO mRNA] CTD PMID:18200517 NCBI chr 4:170,164,071...170,374,790
Ensembl chr 4:170,164,431...170,374,771 		JBrowse link
G Ptx3 pentraxin 3 increases expression
multiple interactions		 ISO Trinitrobenzenesulfonic Acid results in increased expression of PTX3 mRNA
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTX3 mRNA]		 CTD PMID:18200517 NCBI chr 2:150,487,513...150,493,323
Ensembl chr 2:150,487,513...150,493,323 		JBrowse link
G Rab10 RAB10, member RAS oncogene family decreases expression EXP Trinitrobenzenesulfonic Acid results in decreased expression of RAB10 mRNA CTD PMID:23537331 NCBI chr 6:26,267,081...26,319,739
Ensembl chr 6:26,266,859...26,320,193 		JBrowse link
G Rab15 RAB15, member RAS oncogene family increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of RAB15 mRNA CTD PMID:23537331 NCBI chr 6:95,499,584...95,524,073
Ensembl chr 6:95,499,587...95,523,942 		JBrowse link
G Rab39a RAB39A, member RAS oncogene family increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of RAB39A mRNA CTD PMID:23537331 NCBI chr 8:54,088,246...54,105,867
Ensembl chr 8:54,088,129...54,106,483 		JBrowse link
G Rab5a RAB5A, member RAS oncogene family increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of RAB5A mRNA CTD PMID:23537331 NCBI chr 9:6,483,906...6,512,877
Ensembl chr 9:6,484,469...6,512,873 		JBrowse link
G Ramp2 receptor activity modifying protein 2 increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of RAMP2 mRNA CTD PMID:21808981 NCBI chr10:86,187,366...86,190,692
Ensembl chr10:86,188,812...86,231,829 		JBrowse link
G Ramp3 receptor activity modifying protein 3 increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of RAMP3 mRNA CTD PMID:21808981 NCBI chr14:81,527,404...81,544,905
Ensembl chr14:81,527,385...81,544,902 		JBrowse link
G Rap1b RAP1B, member of RAS oncogene family increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of RAP1B mRNA CTD PMID:23537331 NCBI chr 7:53,423,039...53,456,349
Ensembl chr 7:53,423,130...53,456,370 		JBrowse link
G Rasa2 RAS p21 protein activator 2 increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of RASA2 mRNA CTD PMID:23537331 NCBI chr 8:97,119,983...97,236,687
Ensembl chr 8:97,118,802...97,236,671 		JBrowse link
G Rasa3 RAS p21 protein activator 3 increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of RASA3 mRNA CTD PMID:23537331 NCBI chr16:75,855,360...75,969,349
Ensembl chr16:75,855,265...75,970,804 		JBrowse link
G Rasd2 RASD family, member 2 decreases expression EXP Trinitrobenzenesulfonic Acid results in decreased expression of RASD2 mRNA CTD PMID:23537331 NCBI chr19:13,594,291...13,605,016
Ensembl chr19:13,594,291...13,605,016 		JBrowse link
G Rbp1 retinol binding protein 1 multiple interactions
increases expression		 ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of RBP1 mRNA] CTD PMID:17982090 PMID:18200517 NCBI chr 8:99,025,218...99,046,740
Ensembl chr 8:99,025,206...99,046,743 		JBrowse link
G Reg3b regenerating family member 3 beta increases expression
multiple interactions		 ISO Trinitrobenzenesulfonic Acid results in increased expression of REG3A mRNA; Trinitrobenzenesulfonic Acid results in increased expression of REG3B mRNA
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of REG3A mRNA]		 CTD PMID:17982090 PMID:18200517 NCBI chr 4:110,861,775...110,865,015
Ensembl chr 4:110,861,775...110,865,015 		JBrowse link
G Reg3g regenerating family member 3 gamma multiple interactions
increases expression		 ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of REG3G mRNA] CTD PMID:17982090 PMID:18200517 NCBI chr 4:110,922,805...110,927,803
Ensembl chr 4:110,924,168...110,926,723 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions
affects localization
increases phosphorylation
increases expression
increases abundance		 EXP
ISO		 Chalcones inhibits the reaction [Trinitrobenzenesulfonic Acid affects the localization of RELA protein]; dapagliflozin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased phosphorylation of RELA protein]; Iridoid Glycosides inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of RELA mRNA]; Iridoid Glycosides inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of RELA protein]; Mesalamine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased phosphorylation of RELA protein]; oxymatrine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased phosphorylation of RELA protein]; Resveratrol inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of RELA protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of RELA mRNA]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of RELA protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased phosphorylation of RELA protein]; Telmisartan inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of RELA mRNA]; Telmisartan inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of RELA protein]
lancemaside A inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased phosphorylation of RELA protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased phosphorylation of RELA protein]
Trinitrobenzenesulfonic Acid results in increased expression of RELA mRNA; Trinitrobenzenesulfonic Acid results in increased expression of RELA protein
2,4,6-trinitrobenzenesulfonic acid increases abundance of Nf-Kb protein in rat colon		 CTD
RGD		 PMID:16474422 PMID:19597321 PMID:19956958 PMID:21070844 PMID:22410118 More... RGD:152995414 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484 		JBrowse link
G Retnlb resistin like beta increases expression
multiple interactions		 ISO Trinitrobenzenesulfonic Acid results in increased expression of RETNLB mRNA
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of RETNLB mRNA]		 CTD PMID:18200517 NCBI chr11:51,983,482...51,985,368
Ensembl chr11:51,983,483...51,985,368 		JBrowse link
G Rhoq ras homolog family member Q increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of RHOQ mRNA CTD PMID:23537331 NCBI chr 6:7,613,632...7,652,047
Ensembl chr 1:106,622,141...106,623,699 		JBrowse link
G Rmnd1 required for meiotic nuclear division 1 homolog decreases expression ISO Trinitrobenzenesulfonic Acid results in decreased expression of RMND1 mRNA CTD PMID:17982090 NCBI chr 1:40,859,829...40,894,376
Ensembl chr 1:40,859,829...40,894,314 		JBrowse link
G Rnase1 ribonuclease A family member 1, pancreatic increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of RNASE1 mRNA CTD PMID:17982090 NCBI chr15:24,361,924...24,363,633
Ensembl chr15:24,361,927...24,363,624 		JBrowse link
G Rngtt RNA guanylyltransferase and 5'-phosphatase increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of RNGTT mRNA CTD PMID:17982090 NCBI chr 5:47,706,929...47,913,297
Ensembl chr 5:47,706,799...47,913,295 		JBrowse link
G Rprm reprimo, TP53 dependent G2 arrest mediator homolog decreases expression ISO Trinitrobenzenesulfonic Acid results in decreased expression of RPRM mRNA CTD PMID:17982090 NCBI chr 3:38,539,581...38,540,998
Ensembl chr 3:38,539,581...38,540,998 		JBrowse link
G Rreb1 ras responsive element binding protein 1 multiple interactions
decreases expression		 ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of RREB1 mRNA] CTD PMID:18200517 NCBI chr17:26,876,687...27,002,554
Ensembl chr17:26,876,697...27,002,615 		JBrowse link
G RT1-Ba RT1 class II, locus Ba increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of H2-AA mRNA CTD PMID:17982090 NCBI chr20:4,575,134...4,579,727
Ensembl chr20:4,575,134...4,579,744 		JBrowse link
G RT1-Da RT1 class II, locus Da increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of H2-EA mRNA CTD PMID:17982090 NCBI chr20:4,513,464...4,518,457
Ensembl chr20:4,512,911...4,518,455 		JBrowse link
G Ryr1 ryanodine receptor 1 increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of RYR1 mRNA CTD PMID:23537331 NCBI chr 1:84,292,578...84,423,824
Ensembl chr 1:84,292,578...84,423,812 		JBrowse link
G S100a8 S100 calcium binding protein A8 multiple interactions
increases expression		 ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of S100A8 mRNA] CTD PMID:17982090 PMID:18200517 NCBI chr 2:176,166,517...176,167,645
Ensembl chr 2:176,167,124...176,167,643 		JBrowse link
G S100a9 S100 calcium binding protein A9 multiple interactions
increases expression		 ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of S100A9 mRNA] CTD PMID:17982090 PMID:18200517 NCBI chr 2:176,190,361...176,193,182
Ensembl chr 2:176,190,361...176,193,230 		JBrowse link
G Sat1 spermidine/spermine N1-acetyl transferase 1 increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of SAT1 mRNA CTD PMID:12163651 NCBI chr  X:40,158,354...40,161,641
Ensembl chr  X:40,157,046...40,196,813 		JBrowse link
G Scd stearoyl-CoA desaturase increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of SCD1 mRNA CTD PMID:17982090 NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562 		JBrowse link
G Scn10a sodium voltage-gated channel alpha subunit 10 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of SCN10A CTD PMID:15205116 NCBI chr 8:119,350,723...119,462,882
Ensembl chr 8:119,350,724...119,462,614 		JBrowse link
G Selenow selenoprotein W increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of SELENOW mRNA CTD PMID:17982090 NCBI chr 1:76,599,441...76,604,514
Ensembl chr 1:76,598,779...76,604,724
Ensembl chr 1:76,598,779...76,604,724 		JBrowse link
G Serpinb5 serpin family B member 5 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of SERPINB5 mRNA CTD PMID:17982090 NCBI chr13:22,985,557...23,005,756
Ensembl chr13:22,985,557...23,005,756 		JBrowse link
G Serpine2 serpin family E member 2 multiple interactions
increases expression		 ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of SERPINE2 mRNA] CTD PMID:18200517 NCBI chr 9:81,124,746...81,188,866
Ensembl chr 9:81,124,804...81,188,826 		JBrowse link
G Shbg sex hormone binding globulin increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of SHBG mRNA CTD PMID:17982090 NCBI chr10:54,332,939...54,350,409
Ensembl chr10:54,332,941...54,351,057 		JBrowse link
G Sirt1 sirtuin 1 decreases expression EXP Trinitrobenzenesulfonic Acid results in decreased expression of SIRT1 protein CTD PMID:24782617 NCBI chr20:25,307,225...25,329,273
Ensembl chr20:25,306,917...25,329,260 		JBrowse link
G Slc10a1 solute carrier family 10 member 1 decreases expression EXP Trinitrobenzenesulfonic Acid results in decreased expression of SLC10A1 mRNA; Trinitrobenzenesulfonic Acid results in decreased expression of SLC10A1 protein CTD PMID:12044520 NCBI chr 6:100,613,045...100,626,670
Ensembl chr 6:100,613,045...100,626,670 		JBrowse link
G Slc1a1 solute carrier family 1 member 1 decreases expression ISO Trinitrobenzenesulfonic Acid results in decreased expression of SLC1A1 mRNA CTD PMID:17982090 NCBI chr 1:226,549,932...226,631,925
Ensembl chr 1:226,549,842...226,630,402 		JBrowse link
G Slc20a1 solute carrier family 20 member 1 multiple interactions
decreases expression		 ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of SLC20A1 mRNA] CTD PMID:17982090 PMID:18200517 NCBI chr 3:116,427,095...116,441,049
Ensembl chr 3:116,427,098...116,441,051 		JBrowse link
G Slc26a2 solute carrier family 26 member 2 decreases expression ISO Trinitrobenzenesulfonic Acid results in decreased expression of SLC26A2 mRNA CTD PMID:17982090 NCBI chr18:54,648,276...54,666,627
Ensembl chr18:54,652,951...54,666,626 		JBrowse link
G Slc30a10 solute carrier family 30, member 10 decreases expression
multiple interactions		 ISO Trinitrobenzenesulfonic Acid results in decreased expression of SLC30A10 mRNA
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of SLC30A10 mRNA]		 CTD PMID:18200517 NCBI chr13:96,998,143...97,048,076
Ensembl chr13:96,998,143...97,009,103 		JBrowse link
G Slc4a4 solute carrier family 4 member 4 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of SLC4A4 mRNA CTD PMID:17982090 NCBI chr14:18,841,289...19,293,297
Ensembl chr14:18,845,159...19,272,883 		JBrowse link
G Slco1a4 solute carrier organic anion transporter family, member 1a4 decreases expression EXP Trinitrobenzenesulfonic Acid results in decreased expression of SLCO1A4 mRNA; Trinitrobenzenesulfonic Acid results in decreased expression of SLCO1A4 protein CTD PMID:12044520 NCBI chr 4:174,710,004...174,764,810
Ensembl chr 4:174,710,004...175,254,573 		JBrowse link
G Slco1b2 solute carrier organic anion transporter family member 1B2 decreases expression EXP Trinitrobenzenesulfonic Acid results in decreased expression of SLCO1B2 mRNA CTD PMID:12044520 NCBI chr 4:174,551,463...174,619,988
Ensembl chr 4:174,551,480...174,619,981 		JBrowse link
G Slfn4 schlafen family member 4 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of SLFN4 mRNA CTD PMID:17982090 NCBI chr10:67,994,601...68,018,141
Ensembl chr10:68,000,028...68,018,138
Ensembl chr10:68,000,028...68,018,138 		JBrowse link
G Slpi secretory leukocyte peptidase inhibitor multiple interactions
increases expression		 ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of SLPI mRNA] CTD PMID:18200517 NCBI chr 3:153,082,208...153,084,457
Ensembl chr 3:153,082,369...153,084,453 		JBrowse link
G Smc2 structural maintenance of chromosomes 2 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of SMC2 mRNA CTD PMID:17982090 NCBI chr 5:66,806,882...66,853,478
Ensembl chr 5:66,807,011...66,853,242 		JBrowse link
G Smpx small muscle protein, X-linked multiple interactions
decreases expression		 ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of SMPX mRNA] CTD PMID:18200517 NCBI chr  X:37,233,209...37,292,266
Ensembl chr  X:37,234,294...37,276,708 		JBrowse link
G Socs3 suppressor of cytokine signaling 3 decreases expression
multiple interactions
increases abundance		 EXP Trinitrobenzenesulfonic Acid results in decreased expression of SOCS3 protein
cinnamaldehyde inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of SOCS3 protein]; hesperetin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of SOCS3 protein]
2,4,6-trinitrobenzenesulfonic acid increases abundance of Socs3 protein in rat colon		 CTD
RGD		 PMID:33522063 PMID:29572553 RGD:152995414 NCBI chr10:103,193,909...103,197,322
Ensembl chr10:103,193,537...103,197,787 		JBrowse link
G Sparc secreted protein acidic and cysteine rich multiple interactions
increases expression		 ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of SPARC mRNA]; Indomethacin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of SPARC mRNA]; Tretinoin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of SPARC mRNA] CTD PMID:17994277 PMID:18200517 NCBI chr10:39,516,394...39,538,252
Ensembl chr10:39,516,406...39,538,396 		JBrowse link
G Spp1 secreted phosphoprotein 1 increases expression
multiple interactions		 ISO Trinitrobenzenesulfonic Acid results in increased expression of SPP1 mRNA
Trinitrobenzenesulfonic Acid promotes the reaction [SPP1 protein results in increased susceptibility to Dinitrofluorobenzene]		 CTD PMID:14555839 PMID:17982090 NCBI chr14:5,308,885...5,315,120
Ensembl chr14:5,308,885...5,315,162 		JBrowse link
G Sqstm1 sequestosome 1 multiple interactions
increases expression		 EXP dapagliflozin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of SQSTM1 protein]; Mesalamine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of SQSTM1 protein] CTD PMID:33412153 NCBI chr10:34,525,517...34,536,670
Ensembl chr10:34,525,519...34,536,673 		JBrowse link
G Srgn serglycin increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of SRGN mRNA CTD PMID:17982090 NCBI chr20:30,442,810...30,479,549
Ensembl chr20:30,442,813...30,457,406 		JBrowse link
G Srm spermidine synthase multiple interactions
increases expression		 ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of SRM mRNA] CTD PMID:18200517 NCBI chr 5:159,025,875...159,029,076
Ensembl chr 5:159,025,873...159,029,405 		JBrowse link
G Stat1 signal transducer and activator of transcription 1 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of STAT1 mRNA CTD PMID:17982090 NCBI chr 9:49,419,561...49,459,969
Ensembl chr 9:49,419,340...49,588,540 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 increases phosphorylation
multiple interactions		 ISO
EXP		 Trinitrobenzenesulfonic Acid results in increased phosphorylation of STAT3 protein
stattic inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased phosphorylation of STAT3 protein]
bergenin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased phosphorylation of STAT3 protein]; cinnamaldehyde inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased phosphorylation of STAT3 protein]; hesperetin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased phosphorylation of STAT3 protein]		 CTD PMID:25740948 PMID:30365937 PMID:33522063 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057 		JBrowse link
G Stim1 stromal interaction molecule 1 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of STIM1 mRNA CTD PMID:17982090 NCBI chr 1:156,656,246...156,818,777
Ensembl chr 1:156,656,013...156,818,363 		JBrowse link
G Stk17b serine/threonine kinase 17b increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of STK17B mRNA CTD PMID:23537331 NCBI chr 9:55,307,485...55,338,085
Ensembl chr 9:55,307,668...55,338,031 		JBrowse link
G Sulf2 sulfatase 2 multiple interactions
increases expression		 ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of SULF2 mRNA] CTD PMID:18200517 NCBI chr 3:154,822,079...154,904,566
Ensembl chr 3:154,822,085...154,904,415 		JBrowse link
G Tac1 tachykinin, precursor 1 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of TAC1 mRNA CTD PMID:17982090 NCBI chr 4:35,679,183...35,687,180
Ensembl chr 4:35,679,704...35,687,178 		JBrowse link
G Tacr1 tachykinin receptor 1 multiple interactions
affects response to substance		 ISO TACR1 gene mutant form inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of COL1A2 mRNA]; TACR1 gene mutant form inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IGF1 protein]; TACR1 gene mutant form inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TGFB1 protein]; TACR1 gene mutant form inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of VIM mRNA]
TACR1 protein affects the susceptibility to Trinitrobenzenesulfonic Acid		 CTD PMID:20889569 NCBI chr 4:114,920,844...115,089,733
Ensembl chr 4:114,920,844...115,089,733 		JBrowse link
G Tes testin LIM domain protein decreases expression
multiple interactions		 ISO Trinitrobenzenesulfonic Acid results in decreased expression of TES protein
Anisomycin inhibits the reaction [TES protein inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]]; Anisomycin inhibits the reaction [TES protein inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]]; Anisomycin inhibits the reaction [TES protein inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 mRNA]]; Anisomycin inhibits the reaction [TES protein inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 protein]]; Anisomycin inhibits the reaction [TES protein inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]]; Anisomycin inhibits the reaction [TES protein inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]]; TES protein inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of CLDN1 protein]; TES protein inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of TJP1 protein]; TES protein inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]; TES protein inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]; TES protein inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 mRNA]; TES protein inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 protein]; TES protein inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]; TES protein inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; TES protein inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased phosphorylation of MAPK8 protein]		 CTD PMID:39237074 NCBI chr 4:45,365,304...45,403,829
Ensembl chr 4:45,365,285...45,403,829 		JBrowse link
G Tff3 trefoil factor 3 multiple interactions
increases expression		 EXP Active Hexose Correlated Compound inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TFF3 mRNA]; kappa-casein glycomacropeptide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TFF3 mRNA]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TFF3 mRNA] CTD PMID:15867298 PMID:17449585 NCBI chr20:9,193,259...9,197,969
Ensembl chr20:9,193,262...9,198,054 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions
decreases expression
increases expression		 ISO 6-diphenylmethyl-5-(5-isopropyl-2-methoxybenzylamino)-1-azabicyclo(2.2.2)octane-3-carboxylic acid inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TGFB1 protein]; [rifaximin co-treated with Trinitrobenzenesulfonic Acid] results in increased expression of TGFB1 protein; stattic inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TGFB1 mRNA]; TACR1 gene mutant form inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TGFB1 protein]
Trinitrobenzenesulfonic Acid results in decreased expression of TGFB1 mRNA
Trinitrobenzenesulfonic Acid results in increased expression of TGFB1 mRNA; Trinitrobenzenesulfonic Acid results in increased expression of TGFB1 protein		 CTD PMID:20889569 PMID:21599020 PMID:25307695 PMID:25740948 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847 		JBrowse link
G Tgfb2 transforming growth factor, beta 2 decreases expression ISO Trinitrobenzenesulfonic Acid results in decreased expression of TGFB2 mRNA CTD PMID:25307695 NCBI chr13:98,160,075...98,261,771
Ensembl chr13:98,160,087...98,261,405 		JBrowse link
G Tgfbr1 transforming growth factor, beta receptor 1 increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of TGFBR1 mRNA CTD PMID:23537331 NCBI chr 5:61,653,773...61,710,777
Ensembl chr 5:61,653,233...61,710,777 		JBrowse link
G Tgm2 transglutaminase 2 multiple interactions
increases expression		 ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TGM2 mRNA] CTD PMID:18200517 NCBI chr 3:146,772,684...146,801,924
Ensembl chr 3:146,772,687...146,801,981 		JBrowse link
G Tgm3 transglutaminase 3 decreases expression ISO Trinitrobenzenesulfonic Acid results in decreased expression of TGM3 mRNA CTD PMID:17982090 NCBI chr 3:117,228,661...117,264,078
Ensembl chr 3:117,228,661...117,264,075 		JBrowse link
G Thbd thrombomodulin increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of THBD mRNA CTD PMID:17982090 NCBI chr 3:135,863,366...135,867,018
Ensembl chr 3:135,862,835...135,867,193 		JBrowse link
G Thbs1 thrombospondin 1 multiple interactions
increases expression		 ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of THBS1 mRNA] CTD PMID:18200517 NCBI chr 3:105,056,293...105,071,445
Ensembl chr 3:105,056,292...105,071,440 		JBrowse link
G Thy1 Thy-1 cell surface antigen increases expression
multiple interactions		 ISO Trinitrobenzenesulfonic Acid results in increased expression of THY1 mRNA
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of THY1 mRNA]		 CTD PMID:18200517 NCBI chr 8:44,389,495...44,394,688
Ensembl chr 8:44,389,513...44,394,659 		JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 multiple interactions
increases expression		 ISO
EXP		 Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TIMP1 mRNA]
ilomastat affects the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TIMP1 mRNA]; ilomastat affects the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TIMP1 protein]
Trinitrobenzenesulfonic Acid results in increased expression of TIMP1 mRNA; Trinitrobenzenesulfonic Acid results in increased expression of TIMP1 protein		 CTD PMID:17982090 PMID:18200517 PMID:18837084 NCBI chr  X:1,212,969...1,217,714
Ensembl chr  X:1,212,972...1,217,664 		JBrowse link
G Tjp1 tight junction protein 1 multiple interactions
decreases expression		 ISO
EXP		 ginsenoside Re inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of TJP1 protein]; TES protein inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of TJP1 protein]
Trinitrobenzenesulfonic Acid results in decreased expression of TJP1 mRNA; Trinitrobenzenesulfonic Acid results in decreased expression of TJP1 protein
oxymatrine inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of TJP1 mRNA]; oxymatrine inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of TJP1 protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of TJP1 mRNA]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of TJP1 protein]		 CTD PMID:22147983 PMID:22849695 PMID:35290143 PMID:39237074 NCBI chr 1:118,849,838...119,094,492
Ensembl chr 1:118,849,838...119,094,432 		JBrowse link
G Tjp2 tight junction protein 2 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of TJP2 mRNA CTD PMID:25307695 NCBI chr 1:221,709,745...221,838,291
Ensembl chr 1:221,709,745...221,838,295 		JBrowse link
G Tlr2 toll-like receptor 2 increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of TLR2 CTD PMID:16891783 NCBI chr 2:169,200,620...169,206,819
Ensembl chr 2:169,197,419...169,206,630 		JBrowse link
G Tlr4 toll-like receptor 4 multiple interactions
increases expression
decreases expression		 ISO
EXP		 lancemaside A inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TLR4 protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TLR4 protein]
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TLR4 protein]
Trinitrobenzenesulfonic Acid results in increased expression of TLR4; Trinitrobenzenesulfonic Acid results in increased expression of TLR4 protein
Trinitrobenzenesulfonic Acid results in decreased expression of TLR4 mRNA		 CTD PMID:16891783 PMID:19002562 PMID:19597321 PMID:19956958 PMID:19998380 More... NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628 		JBrowse link
G Tlr9 toll-like receptor 9 multiple interactions
increases expression		 EXP oxymatrine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TLR9 protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TLR9 protein] CTD PMID:35290143 NCBI chr 8:106,864,680...106,868,796
Ensembl chr 8:106,864,680...106,868,796 		JBrowse link
G Tmem245 transmembrane protein 245 decreases expression EXP Trinitrobenzenesulfonic Acid results in decreased expression of TMEM245 mRNA CTD PMID:12163651 NCBI chr 5:71,570,952...71,647,915
Ensembl chr 5:71,514,858...71,647,763 		JBrowse link
G Tmt1a thiol methyltransferase 1A multiple interactions
decreases expression		 ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of TMT1A mRNA] CTD PMID:18200517 NCBI chr 7:131,452,099...131,460,154
Ensembl chr 7:131,451,641...131,460,154 		JBrowse link
G Tnc tenascin C multiple interactions
increases expression		 ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNC mRNA] CTD PMID:18200517 NCBI chr 5:77,375,851...77,460,712
Ensembl chr 5:77,375,851...77,460,624 		JBrowse link
G Tnf tumor necrosis factor multiple interactions
increases expression
increases secretion
increases abundance		 ISO
EXP		 [cholan-2,3,24-tryl-2,3,24-trisulfate binds to and results in increased activity of NR1I2 protein] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; [Rifaximin binds to and results in increased activity of NR1I2 protein] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; Anisomycin inhibits the reaction [TES protein inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]]; Anisomycin inhibits the reaction [TES protein inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]]; cholan-2,3,24-tryl-2,3,24-trisulfate inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]; D-JNKI-1 inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; dai-kenchu-to inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF]; Huangqin-Tang inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]; icilin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; lancemaside A inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; Minocycline inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]; notoginsenoside R1 inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; Rifaximin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; seryl-leucyl-isoleucyl-glycyl--arginyl-leucinamide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]; sinomenine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]; sinomenine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; soyasaponin Ab inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; soyasaponin I inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; TES protein inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]; TES protein inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]
4-methylesculetin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; [allicin co-treated with Mesalamine] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; [allicin co-treated with Sulfasalazine] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; [Inosine Monophosphate co-treated with potassium oxonate] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; Active Hexose Correlated Compound inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]; Active Hexose Correlated Compound inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased secretion of TNF protein]; allicin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; Ampicillin inhibits the reaction [Aspirin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]]; Ampicillin inhibits the reaction [Aspirin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]]; Ampicillin inhibits the reaction [Celecoxib promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]]; Ampicillin inhibits the reaction [Celecoxib promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]]; Aspirin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]; Aspirin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; Celecoxib promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]; Celecoxib promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; Chalcones inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; cinnamaldehyde inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]; Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; dapagliflozin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; Dexamethasone inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]; Dinoprostone analog inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; hesperetin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; Hydroxamic Acids analog promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]; iberogast inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]; Inosine Monophosphate inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; Iridoid Glycosides inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]; Isatin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF]; Mesalamine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; nitroaspirin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]; oxymatrine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]; oxymatrine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; potassium oxonate inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; Prednisolone inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; Resveratrol inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; SC 560 promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; SCH 442416 inhibits the reaction [Inosine Monophosphate inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased secretion of TNF protein]; Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]; Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; Telmisartan inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]
Trinitrobenzenesulfonic Acid results in increased expression of TNF; Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA; Trinitrobenzenesulfonic Acid results in increased expression of TNF protein
2,4,6-trinitrobenzenesulfonic acid increases abundance of Tnfa protein in rat colon		 CTD
RGD		 PMID:11717450 PMID:12717850 PMID:16474422 PMID:16782535 PMID:16867261 More... RGD:152995414 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tnfrsf25 TNF receptor superfamily member 25 increases response to substance ISO TNFRSF25 protein results in increased susceptibility to Trinitrobenzenesulfonic Acid CTD PMID:20980995 NCBI chr 5:162,621,669...162,626,341
Ensembl chr 5:162,622,075...162,626,341 		JBrowse link
G Tnfsf11 TNF superfamily member 11 decreases expression ISO Trinitrobenzenesulfonic Acid results in decreased expression of TNFSF11 protein CTD PMID:23747339 NCBI chr15:53,673,850...53,705,325
Ensembl chr15:53,673,877...53,705,445 		JBrowse link
G Tnfsf15 TNF superfamily member 15 increases response to substance ISO TNFSF15 protein results in increased susceptibility to Trinitrobenzenesulfonic Acid CTD PMID:20980995 NCBI chr 5:77,134,885...77,156,171
Ensembl chr 5:77,139,878...77,156,228 		JBrowse link
G Tnfsf4 TNF superfamily member 4 increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of TNFSF4 mRNA CTD PMID:23537331 NCBI chr13:73,723,329...73,746,809
Ensembl chr13:73,723,329...73,746,788 		JBrowse link
G Tp53 tumor protein p53 multiple interactions
increases expression		 ISO
EXP		 D-JNKI-1 inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of TRP53 protein]
Trinitrobenzenesulfonic Acid results in increased expression of TRP53 protein
Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased phosphorylation of and results in increased activity of TP53 protein]; Trinitrobenzenesulfonic Acid results in increased phosphorylation of and results in increased activity of TP53 protein		 CTD PMID:22427801 PMID:30503585 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
G Trim15 tripartite motif containing 15 multiple interactions
increases expression		 ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TRIM15 mRNA] CTD PMID:18200517 NCBI chr20:1,700,905...1,710,249
Ensembl chr20:1,700,905...1,710,249 		JBrowse link
G Trim16 tripartite motif-containing 16 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of TRIM16 mRNA CTD PMID:19524605 PMID:22609641 NCBI chr10:47,485,982...47,509,010
Ensembl chr10:47,486,297...47,551,907 		JBrowse link
G Trip4 thyroid hormone receptor interactor 4 increases expression
multiple interactions		 EXP Trinitrobenzenesulfonic Acid results in increased expression of TRIP4 protein
bergenin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TRIP4 protein]		 CTD PMID:30365937 NCBI chr 8:66,351,861...66,439,679
Ensembl chr 8:66,353,248...66,439,774 		JBrowse link
G Trpc3 transient receptor potential cation channel, subfamily C, member 3 decreases expression EXP Trinitrobenzenesulfonic Acid results in decreased expression of TRPC3 mRNA CTD PMID:23537331 NCBI chr 2:119,481,313...119,619,333
Ensembl chr 2:119,481,400...119,558,855 		JBrowse link
G Trpm8 transient receptor potential cation channel, subfamily M, member 8 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of TRPM8 mRNA CTD PMID:23596210 NCBI chr 9:88,897,039...88,990,167
Ensembl chr 9:88,903,880...88,988,552 		JBrowse link
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 multiple interactions
decreases expression
increases expression		 EXP topiramate inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of TRPV1 mRNA]
Trinitrobenzenesulfonic Acid results in increased expression of TRPV1 mRNA; Trinitrobenzenesulfonic Acid results in increased expression of TRPV1 protein		 CTD PMID:17698068 PMID:17991707 PMID:21849664 PMID:25445197 NCBI chr10:57,851,428...57,876,513
Ensembl chr10:57,851,428...57,876,513 		JBrowse link
G Trpv4 transient receptor potential cation channel, subfamily V, member 4 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of TRPV4 mRNA CTD PMID:22882778 NCBI chr12:41,938,533...41,977,517
Ensembl chr12:41,938,560...41,977,517 		JBrowse link
G Trpv5 transient receptor potential cation channel, subfamily V, member 5 multiple interactions ISO KL protein inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of TRPV5 protein]; Trinitrobenzenesulfonic Acid results in decreased expression of and results in increased metabolism of TRPV5 protein CTD PMID:23747339 NCBI chr 4:70,536,432...70,562,743
Ensembl chr 4:70,536,440...70,562,745 		JBrowse link
G Txndc16 thioredoxin domain containing 16 decreases expression ISO Trinitrobenzenesulfonic Acid results in decreased expression of TXNDC16 mRNA CTD PMID:17982090 NCBI chr15:18,351,688...18,425,833
Ensembl chr15:18,351,694...18,425,722 		JBrowse link
G Tyrobp transmembrane immune signaling adaptor Tyrobp multiple interactions
increases expression		 ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TYROBP mRNA] CTD PMID:17982090 PMID:18200517 NCBI chr 1:85,672,931...85,676,856
Ensembl chr 1:85,672,994...85,676,848 		JBrowse link
G Ubc ubiquitin C increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of UBC mRNA CTD PMID:12163651 NCBI chr12:31,239,149...31,243,924
Ensembl chr12:31,239,152...31,243,925 		JBrowse link
G Ubd ubiquitin D increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of UBD mRNA CTD PMID:17982090 NCBI chr20:1,385,487...1,387,438
Ensembl chr20:1,385,864...1,408,639
Ensembl chr20:1,385,864...1,408,639 		JBrowse link
G Ube2w ubiquitin-conjugating enzyme E2W decreases expression ISO Trinitrobenzenesulfonic Acid results in decreased expression of UBE2W mRNA CTD PMID:17982090 NCBI chr 5:2,690,742...2,754,491
Ensembl chr 5:2,690,763...2,814,965 		JBrowse link
G Ugt1a6 UDP glucuronosyltransferase family 1 member A6 decreases expression EXP Trinitrobenzenesulfonic Acid results in decreased expression of UGT1A6 mRNA CTD PMID:12163651 NCBI chr 9:88,747,213...88,808,465
Ensembl chr 9:88,713,184...88,808,465 		JBrowse link
G Usp8 ubiquitin specific peptidase 8 decreases expression EXP Trinitrobenzenesulfonic Acid results in decreased expression of USP8 mRNA CTD PMID:23537331 NCBI chr 3:113,962,136...114,009,683
Ensembl chr 3:113,962,164...114,009,666 		JBrowse link
G Vcam1 vascular cell adhesion molecule 1 increases expression
multiple interactions		 ISO
EXP		 Trinitrobenzenesulfonic Acid results in increased expression of VCAM1 mRNA
Trinitrobenzenesulfonic Acid results in increased expression of VCAM1 mRNA; Trinitrobenzenesulfonic Acid results in increased expression of VCAM1 protein
Hydroxamic Acids analog promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of VCAM1 mRNA]; Resveratrol inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of VCAM1 protein]; Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of VCAM1 mRNA]		 CTD PMID:17982090 PMID:22029500 PMID:30503585 NCBI chr 2:204,038,120...204,057,852
Ensembl chr 2:204,038,114...204,057,958 		JBrowse link
G Vcan versican multiple interactions
increases expression		 ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of VCAN mRNA] CTD PMID:18200517 NCBI chr 2:20,761,718...20,860,637
Ensembl chr 2:20,761,718...20,860,637 		JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions
increases expression		 EXP
ISO		 Ampicillin inhibits the reaction [Aspirin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of VEGFA mRNA]]; Ampicillin inhibits the reaction [Celecoxib promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of VEGFA mRNA]]; Aspirin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of VEGFA mRNA]; Celecoxib promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of VEGFA mRNA]
NTSR1 protein affects the reaction [Trinitrobenzenesulfonic Acid results in increased expression of VEGFA mRNA]		 CTD PMID:21893697 PMID:25307345 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641 		JBrowse link
G Vim vimentin multiple interactions
increases expression		 ISO 6-diphenylmethyl-5-(5-isopropyl-2-methoxybenzylamino)-1-azabicyclo(2.2.2)octane-3-carboxylic acid inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of VIM mRNA]; TACR1 gene mutant form inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of VIM mRNA] CTD PMID:20889569 NCBI chr17:76,668,701...76,677,186
Ensembl chr17:76,668,647...76,677,187 		JBrowse link
G Vnn1 vanin 1 increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of VNN1 mRNA; Trinitrobenzenesulfonic Acid results in increased expression of VNN1 protein CTD PMID:23307618 NCBI chr 1:21,537,084...21,547,395
Ensembl chr 1:21,537,094...21,547,395 		JBrowse link
G Vwf von Willebrand factor multiple interactions
increases expression		 ISO NTS protein promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of VWF protein] CTD PMID:25307345 NCBI chr 4:158,360,152...158,491,539
Ensembl chr 4:158,360,152...158,491,539 		JBrowse link
G Wdr48 WD repeat domain 48 decreases expression ISO Trinitrobenzenesulfonic Acid results in decreased expression of WDR48 mRNA CTD PMID:17982090 NCBI chr 8:119,622,053...119,655,264
Ensembl chr 8:119,622,048...119,655,264 		JBrowse link
G Wfdc18 WAP four-disulfide core domain 18 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of WFDC18 mRNA CTD PMID:17982090 NCBI chr10:68,588,818...68,590,972
Ensembl chr10:68,588,818...68,589,671 		JBrowse link
G Zc3h11a zinc finger CCCH-type containing 11A decreases expression ISO Trinitrobenzenesulfonic Acid results in decreased expression of ZC3H11A mRNA CTD PMID:17982090 NCBI chr13:45,073,422...45,113,901
Ensembl chr13:45,071,718...45,114,009 		JBrowse link
G Zfp36l2 zinc finger protein 36, C3H type-like 2 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of ZFP36L2 mRNA CTD PMID:17982090 NCBI chr 6:10,490,032...10,494,073
Ensembl chr 6:10,490,032...10,494,064 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19880
    role 19850
      application 19695
        reagent 18057
          2,4,6-trinitrobenzenesulfonic acid 435
Path 2
Term Annotations click to browse term
  CHEBI ontology 19880
    subatomic particle 19878
      composite particle 19878
        hadron 19878
          baryon 19878
            nucleon 19878
              atomic nucleus 19878
                atom 19878
                  main group element atom 19817
                    p-block element atom 19817
                      chalcogen 19569
                        oxygen atom 19541
                          oxygen molecular entity 19541
                            hydroxides 19347
                              oxoacid 18782
                                chalcogen oxoacid 13784
                                  sulfur oxoacid 13573
                                    sulfonic acid 11618
                                      sulfo group 9953
                                        organosulfonic acid 9953
                                          arenesulfonic acid 687
                                            2,4,6-trinitrobenzenesulfonic acid 435
paths to the root