CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: 1-fluoro-2,4-dinitrobenzene
Accession: CHEBI:53049
browse the term
Definition: The organofluorine compound that is benzene with a fluoro substituent at the 1-position and two nitro substituents in the 2- and 4-positions.
Synonyms: related_synonym: 1,2,4-Fluorodinitrobenzene; 2,4-Dinitro-1-fluorobenzene; 2,4-Dinitrobenzene fluoride; 2,4-Dinitrobenzenefluoride; 2,4-Dinitrofluorobenzene; 2,4-Dinitrophenyl fluoride; 2,4-Dnfb; DFB; DNFB; Dinitrofluorobenzene; FDNB; Fluoro-2,4-dinitrobenzene; Fluorodinitrobenzene; Formula=C6H3FN2O4; InChI=1S/C6H3FN2O4/c7-5-2-1-4(8(10)11)3-6(5)9(12)13/h1-3H; InChIKey=LOTKRQAVGJMPNV-UHFFFAOYSA-N; SMILES=[O-][N+](=O)c1ccc(F)c(c1)[N+]([O-])=O
xref: Beilstein:398632; CAS:70-34-8; Gmelin:564641
xref_mesh: MESH:D004139
xref: MetaCyc:CPD-8983; PMID:10570824; PMID:10868578; PMID:10910205; PMID:11733853; PMID:11739495; PMID:12093520; PMID:14630357; PMID:15307184; PMID:15328335; PMID:15696100; PMID:15801672; PMID:17517538; PMID:17917283; PMID:1854019; PMID:18827366; PMID:18965207; PMID:2100626; PMID:2176869; PMID:23076500; PMID:23190882; PMID:23199096; PMID:23286949; PMID:23395695; PMID:23474456; PMID:23529340; PMID:2420897; PMID:24399719; PMID:2807957; PMID:3121792; PMID:7900773; PMID:7994925; PMID:8248333; PMID:8466279; PMID:9326394; Reaxys:398632; Wikipedia:1-Fluoro-2\,4-dinitrobenzene
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Adm
adrenomedullin
increases expression
ISO
Dinitrofluorobenzene results in increased expression of ADM mRNA
CTD
PMID:23999411
NCBI chr 1:164,745,484...164,747,655
Ensembl chr 1:164,745,466...164,747,654
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Akirin2
akirin 2
increases expression
ISO
Dinitrofluorobenzene results in increased expression of AKIRIN2 mRNA
CTD
PMID:23999411
NCBI chr 5:49,108,231...49,122,566
Ensembl chr 5:49,108,220...49,122,568
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Akt1
AKT serine/threonine kinase 1
increases phosphorylation
ISO
Dinitrofluorobenzene results in increased phosphorylation of AKT1 protein
CTD
PMID:23445166
NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
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Aqp3
aquaporin 3 (Gill blood group)
increases expression
ISO
Dinitrofluorobenzene results in increased expression of AQP3 mRNA
CTD
PMID:21362464
NCBI chr 5:56,239,200...56,244,718
Ensembl chr 5:56,239,201...56,244,720
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Arg2
arginase 2
increases expression
ISO
Dinitrofluorobenzene results in increased expression of ARG2 mRNA
CTD
PMID:23999411
NCBI chr 6:97,936,002...97,961,379
Ensembl chr 6:97,936,002...97,961,378
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Atf3
activating transcription factor 3
increases expression
ISO
Dinitrofluorobenzene results in increased expression of ATF3 mRNA
CTD
PMID:23999411
NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631
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Babam2
BRISC and BRCA1 A complex member 2
increases expression
ISO
Dinitrofluorobenzene results in increased expression of BABAM2 mRNA
CTD
PMID:23999411
NCBI chr 6:24,369,021...24,788,416
Ensembl chr 6:24,369,022...24,833,951
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Casp1
caspase 1
multiple interactions
ISO
cordycepin inhibits the reaction [Dinitrofluorobenzene results in increased expression of and results in increased activity of CASP1 protein]; Dinitrofluorobenzene results in increased expression of and results in increased activity of CASP1 protein
CTD
PMID:30183461
NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383
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Ccl17
C-C motif chemokine ligand 17
multiple interactions increases expression
ISO
cordycepin inhibits the reaction [Dinitrofluorobenzene results in increased expression of CCL17 mRNA]
CTD
PMID:30183461
NCBI chr19:10,202,128...10,203,903
Ensembl chr19:10,202,128...10,203,819
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Ccl2
C-C motif chemokine ligand 2
multiple interactions increases expression
ISO
[CCL2 protein results in increased expression of CCR2 protein] which affects the susceptibility to Dinitrofluorobenzene Dinitrofluorobenzene results in increased expression of CCL2 mRNA
CTD
PMID:15719370 PMID:21362464
NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
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Ccl3
C-C motif chemokine ligand 3
increases expression
ISO
Dinitrofluorobenzene results in increased expression of CCL3 mRNA
CTD
PMID:15719370
NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938
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Ccl4
C-C motif chemokine ligand 4
increases expression
ISO
Dinitrofluorobenzene results in increased expression of CCL4 mRNA Dinitrofluorobenzene results in increased expression of CCL4 protein
CTD
PMID:15719370 PMID:18353026
NCBI chr10:68,466,394...68,468,229
Ensembl chr10:68,452,052...68,468,231
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Ccl5
C-C motif chemokine ligand 5
increases expression
ISO
Dinitrofluorobenzene results in increased expression of CCL5 mRNA; Dinitrofluorobenzene results in increased expression of CCL5 protein
CTD
PMID:15719370
NCBI chr10:68,322,826...68,327,380
Ensembl chr10:68,322,829...68,327,377
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Ccne2
cyclin E2
increases expression
ISO
Dinitrofluorobenzene results in increased expression of CCNE2 mRNA
CTD
PMID:23999411
NCBI chr 5:24,285,078...24,298,258
Ensembl chr 5:24,284,922...24,297,632
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Ccr2
C-C motif chemokine receptor 2
increases expression multiple interactions
ISO
Dinitrofluorobenzene results in increased expression of CCR2 mRNA [CCL2 protein results in increased expression of CCR2 protein] which affects the susceptibility to Dinitrofluorobenzene
CTD
PMID:21362464
NCBI chr 8:123,734,465...123,742,483
Ensembl chr 8:123,734,430...123,742,100
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Ccr3
C-C motif chemokine receptor 3
multiple interactions increases expression
ISO
cordycepin inhibits the reaction [Dinitrofluorobenzene results in increased expression of CCR3 mRNA]
CTD
PMID:30183461
NCBI chr 8:123,586,100...123,634,178
Ensembl chr 8:123,616,236...123,634,990
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Ccr6
C-C motif chemokine receptor 6
decreases expression
ISO
Dinitrofluorobenzene results in decreased expression of CCR6 protein
CTD
PMID:15924226
NCBI chr 1:52,474,477...52,508,301
Ensembl chr 1:52,474,168...52,498,603
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Cd83
CD83 molecule
increases expression
ISO
Dinitrofluorobenzene results in increased expression of CD83 protein
CTD
PMID:21362464
NCBI chr17:20,887,309...20,907,009
Ensembl chr17:20,887,309...20,907,083
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Cd86
CD86 molecule
increases expression
ISO
Dinitrofluorobenzene results in increased expression of CD86 protein
CTD
PMID:21362464
NCBI chr11:64,142,193...64,200,816
Ensembl chr11:64,163,828...64,200,818
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Creb1
cAMP responsive element binding protein 1
affects expression
ISO
Dinitrofluorobenzene affects the expression of CREB1 mRNA
CTD
PMID:20385217
NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816
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Crem
cAMP responsive element modulator
increases expression
ISO
Dinitrofluorobenzene results in increased expression of CREM mRNA
CTD
PMID:21362464
NCBI chr17:54,238,889...54,305,989
Ensembl chr17:54,239,030...54,305,989
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Cxcl10
C-X-C motif chemokine ligand 10
increases expression decreases expression
ISO
Dinitrofluorobenzene results in increased expression of CXCL10 mRNA; Dinitrofluorobenzene results in increased expression of CXCL10 protein Dinitrofluorobenzene results in decreased expression of CXCL10 mRNA
CTD
PMID:15719370 PMID:23445166
NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975
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Cxcl3
C-X-C motif chemokine ligand 3
increases expression
ISO
Dinitrofluorobenzene results in increased expression of CXCL1 mRNA
CTD
PMID:15719370
NCBI chr14:17,287,727...17,289,451
Ensembl chr14:17,270,146...17,289,511
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Cxcr4
C-X-C motif chemokine receptor 4
decreases expression
ISO
Dinitrofluorobenzene results in decreased expression of CXCR4 protein
CTD
PMID:15924226
NCBI chr13:40,077,976...40,081,883
Ensembl chr13:40,077,976...40,081,883
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Cytip
cytohesin 1 interacting protein
increases expression
ISO
Dinitrofluorobenzene results in increased expression of CYTIP mRNA
CTD
PMID:21362464
NCBI chr 3:42,698,058...42,774,955
Ensembl chr 3:42,698,768...42,725,993
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Dhrs2
dehydrogenase/reductase 2
increases expression
ISO
Dinitrofluorobenzene results in increased expression of DHRS2 mRNA
CTD
PMID:23999411
NCBI chr15:28,688,881...28,703,646
Ensembl chr15:28,688,940...28,703,644
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Dnajb4
DnaJ heat shock protein family (Hsp40) member B4
increases expression
ISO
Dinitrofluorobenzene results in increased expression of DNAJB4 mRNA
CTD
PMID:23999411
NCBI chr 2:241,129,346...241,159,272
Ensembl chr 2:241,130,340...241,159,089
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Eif1
eukaryotic translation initiation factor 1
increases expression
ISO
Dinitrofluorobenzene results in increased expression of EIF1 mRNA
CTD
PMID:23999411
NCBI chr10:85,246,751...85,248,842
Ensembl chr10:85,246,764...85,427,327
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Epc1
enhancer of polycomb homolog 1
increases expression
ISO
Dinitrofluorobenzene results in increased expression of EPC1 mRNA
CTD
PMID:23999411
NCBI chr17:54,503,358...54,594,444
Ensembl chr17:54,503,358...54,594,425
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Fosb
FosB proto-oncogene, AP-1 transcription factor subunit
increases expression
ISO
Dinitrofluorobenzene results in increased expression of FOSB mRNA
CTD
PMID:23999411
NCBI chr 1:78,954,312...78,961,492
Ensembl chr 1:78,954,115...78,961,465
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Gclc
glutamate-cysteine ligase, catalytic subunit
increases expression
ISO
Dinitrofluorobenzene results in increased expression of GCLC mRNA
CTD
PMID:23999411
NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544
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Gclm
glutamate cysteine ligase, modifier subunit
increases expression
ISO
Dinitrofluorobenzene results in increased expression of GCLM mRNA
CTD
PMID:23999411
NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535
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H2ax
H2A.X variant histone
increases expression
ISO
Dinitrofluorobenzene results in increased expression of H2AX mRNA
CTD
PMID:23999411
NCBI chr 8:44,671,907...44,673,262
Ensembl chr 8:44,671,786...44,673,239
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Hmox1
heme oxygenase 1
increases expression
ISO
Dinitrofluorobenzene results in increased expression of HMOX1 mRNA
CTD
PMID:23445166 PMID:25091725
NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
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Hspa1a
heat shock protein family A (Hsp70) member 1A
increases expression
ISO
Dinitrofluorobenzene results in increased expression of HSPA1A mRNA
CTD
PMID:23999411
NCBI chr20:3,870,765...3,873,221
Ensembl chr20:3,856,006...3,873,227
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Hspa6l-ps1
heat shock protein family A (Hsp70) member 6 like, pseudogene 1
increases expression
ISO
Dinitrofluorobenzene results in increased expression of HSPA6 mRNA
CTD
PMID:23999411
NCBI chr13:83,273,176...83,274,317
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Hsph1
heat shock protein family H (Hsp110) member 1
increases expression
ISO
Dinitrofluorobenzene results in increased expression of HSPH1 mRNA
CTD
PMID:23999411
NCBI chr12:5,390,916...5,410,224
Ensembl chr12:5,390,922...5,410,224
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Icam1
intercellular adhesion molecule 1
multiple interactions increases expression
ISO
doramapimod inhibits the reaction [Dinitrofluorobenzene results in increased expression of ICAM1 protein]
CTD
PMID:19427879
NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
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Ifng
interferon gamma
increases expression multiple interactions
ISO
Dinitrofluorobenzene results in increased expression of IFNG mRNA; Dinitrofluorobenzene results in increased expression of IFNG protein oleanolic acid 3-acetate inhibits the reaction [Dinitrofluorobenzene results in increased expression of IFNG mRNA]
CTD
PMID:11243917 PMID:11244134 PMID:23499868
NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
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Il10
interleukin 10
increases expression
ISO
Dinitrofluorobenzene results in increased expression of IL10 mRNA
CTD
PMID:11243917 PMID:23499868
NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
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Il12b
interleukin 12B
increases expression
ISO
Dinitrofluorobenzene results in increased expression of IL12B mRNA
CTD
PMID:11708898
NCBI chr10:28,888,832...28,903,802
Ensembl chr10:28,893,008...28,902,903
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Il15ra
interleukin 15 receptor subunit alpha
increases response to substance
ISO
IL15RA protein results in increased susceptibility to Dinitrofluorobenzene
CTD
PMID:15719370
NCBI chr17:66,802,300...66,831,973
Ensembl chr17:66,802,334...66,832,278
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Il17a
interleukin 17A
increases expression multiple interactions
ISO
Dinitrofluorobenzene results in increased expression of IL17A mRNA oleanolic acid 3-acetate inhibits the reaction [Dinitrofluorobenzene results in increased expression of IL17A mRNA]
CTD
PMID:23499868
NCBI chr 9:23,144,402...23,147,889
Ensembl chr 9:23,144,402...23,147,889
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Il17f
interleukin 17F
increases expression
ISO
Dinitrofluorobenzene results in increased expression of IL17F mRNA
CTD
PMID:23445166
NCBI chr 9:23,190,094...23,201,482
Ensembl chr 9:23,190,100...23,201,482
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Il1a
interleukin 1 alpha
increases expression affects secretion
ISO
Dinitrofluorobenzene results in increased expression of IL1A mRNA; Dinitrofluorobenzene results in increased expression of IL1A protein Dinitrofluorobenzene affects the secretion of IL1A protein
CTD
PMID:8006454 PMID:12781210
NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
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Il2
interleukin 2
increases expression
ISO
Dinitrofluorobenzene results in increased expression of IL2 mRNA; Dinitrofluorobenzene results in increased expression of IL2 protein
CTD
PMID:11244134 PMID:22381623
NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566
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Il4
interleukin 4
increases expression multiple interactions increases secretion
ISO
Dinitrofluorobenzene results in increased expression of IL4 mRNA cordycepin inhibits the reaction [Dinitrofluorobenzene results in increased secretion of IL4 protein]
CTD
PMID:23499868 PMID:30183461
NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
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Il4r
interleukin 4 receptor
increases expression
ISO
Dinitrofluorobenzene results in increased expression of IL4RA protein
CTD
PMID:22381623
NCBI chr 1:180,115,061...180,139,981
Ensembl chr 1:180,115,120...180,139,980
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Il6
interleukin 6
increases secretion multiple interactions
ISO
Dinitrofluorobenzene results in increased secretion of IL6 protein cordycepin inhibits the reaction [Dinitrofluorobenzene results in increased secretion of IL6 protein]
CTD
PMID:30183461
NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
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Maff
MAF bZIP transcription factor F
increases expression
ISO
Dinitrofluorobenzene results in increased expression of MAFF mRNA
CTD
PMID:23999411
NCBI chr 7:110,912,367...110,923,711
Ensembl chr 7:110,912,499...110,923,851
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Mapk1
mitogen activated protein kinase 1
increases phosphorylation multiple interactions
ISO
Dinitrofluorobenzene results in increased phosphorylation of MAPK1 protein Fluorescein-5-isothiocyanate inhibits the reaction [Dinitrofluorobenzene results in increased phosphorylation of MAPK1 protein]
CTD
PMID:27129696
NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
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Mapk14
mitogen activated protein kinase 14
increases phosphorylation
ISO
Dinitrofluorobenzene results in increased phosphorylation of MAPK14 protein
CTD
PMID:19427879
NCBI chr20:6,749,646...6,810,590
Ensembl chr20:6,749,670...6,810,589
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Mapk3
mitogen activated protein kinase 3
increases phosphorylation multiple interactions
ISO
Dinitrofluorobenzene results in increased phosphorylation of MAPK3 protein Fluorescein-5-isothiocyanate inhibits the reaction [Dinitrofluorobenzene results in increased phosphorylation of MAPK3 protein]
CTD
PMID:27129696
NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
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Mapk8
mitogen-activated protein kinase 8
increases phosphorylation multiple interactions
ISO
Dinitrofluorobenzene results in increased phosphorylation of MAPK8 protein Fluorescein-5-isothiocyanate inhibits the reaction [Dinitrofluorobenzene results in increased phosphorylation of MAPK8 protein]
CTD
PMID:27129696
NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981
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Mapk9
mitogen-activated protein kinase 9
increases phosphorylation multiple interactions
ISO
Dinitrofluorobenzene results in increased phosphorylation of MAPK9 protein Fluorescein-5-isothiocyanate inhibits the reaction [Dinitrofluorobenzene results in increased phosphorylation of MAPK9 protein]
CTD
PMID:27129696
NCBI chr10:34,169,661...34,211,138
Ensembl chr10:34,169,675...34,210,178
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Mif
macrophage migration inhibitory factor
increases expression
ISO
Dinitrofluorobenzene results in increased expression of MIF mRNA
CTD
PMID:11244134
NCBI chr20:12,790,919...12,791,784
Ensembl chr20:12,790,902...12,799,504
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Mxd1
max dimerization protein 1
increases expression
ISO
Dinitrofluorobenzene results in increased expression of MXD1 mRNA
CTD
PMID:21362464
NCBI chr 4:119,097,353...119,118,080
Ensembl chr 4:119,097,353...119,117,751
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Nampt
nicotinamide phosphoribosyltransferase
increases expression
ISO
Dinitrofluorobenzene results in increased expression of NAMPT mRNA
CTD
PMID:21362464
NCBI chr 6:49,425,316...49,462,109
Ensembl chr 6:49,424,332...49,462,100
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Nfe2l2
NFE2 like bZIP transcription factor 2
increases expression
ISO
Dinitrofluorobenzene results in increased expression of NFE2L2 protein
CTD
PMID:19427879 PMID:26022718
NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737
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Nfkb1
nuclear factor kappa B subunit 1
decreases expression
ISO
Dinitrofluorobenzene results in decreased expression of NFKB1 mRNA
CTD
PMID:20385217
NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404
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Nqo1
NAD(P)H quinone dehydrogenase 1
increases expression
ISO
Dinitrofluorobenzene results in increased expression of NQO1 mRNA
CTD
PMID:23445166
NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
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Nr2f2
nuclear receptor subfamily 2, group F, member 2
increases expression
ISO
Dinitrofluorobenzene results in increased expression of NR2F2 mRNA
CTD
PMID:23999411
NCBI chr 1:124,008,282...124,022,521
Ensembl chr 1:124,009,181...124,022,031
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Ntrk2
neurotrophic receptor tyrosine kinase 2
increases expression
ISO
Dinitrofluorobenzene results in increased expression of NTRK2 mRNA
CTD
PMID:23999411
NCBI chr17:5,558,992...5,870,299
Ensembl chr17:5,559,043...5,869,136
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Peg10
paternally expressed 10
increases expression
ISO
Dinitrofluorobenzene results in increased expression of PEG10 mRNA
CTD
PMID:23999411
NCBI chr 4:32,842,441...32,855,639
Ensembl chr 4:32,848,493...32,852,621
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Pmaip1
phorbol-12-myristate-13-acetate-induced protein 1
increases expression
ISO
Dinitrofluorobenzene results in increased expression of PMAIP1 mRNA
CTD
PMID:23999411
NCBI chr18:59,986,020...59,992,434
Ensembl chr18:59,986,017...59,992,429
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Ptgs2
prostaglandin-endoperoxide synthase 2
increases expression multiple interactions
ISO
Dinitrofluorobenzene results in increased expression of PTGS2 mRNA; Dinitrofluorobenzene results in increased expression of PTGS2 protein [N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in decreased activity of PTGS2 protein] which affects the susceptibility to Dinitrofluorobenzene
CTD
PMID:21362464
NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
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Ptx3
pentraxin 3
increases expression
ISO
Dinitrofluorobenzene results in increased expression of PTX3 mRNA
CTD
PMID:23999411
NCBI chr 2:150,487,513...150,493,323
Ensembl chr 2:150,487,513...150,493,323
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Rgs16
regulator of G-protein signaling 16
increases expression
ISO
Dinitrofluorobenzene results in increased expression of RGS16 mRNA
CTD
PMID:23999411
NCBI chr13:65,887,668...65,892,862
Ensembl chr13:65,887,530...65,892,857
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Slc2a3
solute carrier family 2 member 3
increases expression
ISO
Dinitrofluorobenzene results in increased expression of SLC2A3 mRNA
CTD
PMID:21362464
NCBI chr 4:155,960,944...156,026,000
Ensembl chr 4:155,960,946...156,025,472
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Spp1
secreted phosphoprotein 1
multiple interactions increases response to substance
ISO
Trinitrobenzenesulfonic Acid promotes the reaction [SPP1 protein results in increased susceptibility to Dinitrofluorobenzene]
CTD
PMID:14555839
NCBI chr14:5,308,885...5,315,120
Ensembl chr14:5,308,885...5,315,162
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Taf7
TATA-box binding protein associated factor 7
increases expression
ISO
Dinitrofluorobenzene results in increased expression of TAF7 mRNA
CTD
PMID:23999411
NCBI chr18:29,459,937...29,462,086
Ensembl chr18:29,452,943...29,462,134
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Tgfb1
transforming growth factor, beta 1
increases expression
ISO
Dinitrofluorobenzene results in increased expression of TGFB1 mRNA
CTD
PMID:11244134
NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
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Ticam2
TIR domain containing adaptor molecule 2
increases expression
ISO
Dinitrofluorobenzene results in increased expression of TICAM2 mRNA
CTD
PMID:23999411
NCBI chr18:39,289,902...39,311,462
Ensembl chr18:39,294,453...39,311,462
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Tnf
tumor necrosis factor
affects expression increases expression multiple interactions increases secretion
ISO
Dinitrofluorobenzene affects the expression of TNF mRNA Dinitrofluorobenzene results in increased expression of TNF mRNA cordycepin inhibits the reaction [Dinitrofluorobenzene results in increased secretion of TNF protein]; oleanolic acid 3-acetate inhibits the reaction [Dinitrofluorobenzene results in increased expression of TNF mRNA]
CTD
PMID:20385217 PMID:23499868 PMID:30183461
NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
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Tnfrsf10b
TNF receptor superfamily member 10b
increases expression
ISO
Dinitrofluorobenzene results in increased expression of TNFRSF10A mRNA
CTD
PMID:23999411
NCBI chr15:44,840,386...44,868,318
Ensembl chr15:44,840,386...44,867,467
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Trib1
tribbles pseudokinase 1
increases expression
ISO
Dinitrofluorobenzene results in increased expression of TRIB1 mRNA
CTD
PMID:23999411
NCBI chr 7:91,206,579...91,213,126
Ensembl chr 7:91,206,579...91,214,731
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Trim27
tripartite motif-containing 27
increases expression
ISO
Dinitrofluorobenzene results in increased expression of TRIM27 mRNA
CTD
PMID:23999411
NCBI chr17:43,538,282...43,550,633
Ensembl chr17:43,538,285...43,550,643
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Tslp
thymic stromal lymphopoietin
increases secretion multiple interactions increases expression
ISO
Dinitrofluorobenzene results in increased secretion of TSLP protein cordycepin inhibits the reaction [Dinitrofluorobenzene results in increased expression of TSLP mRNA]; cordycepin inhibits the reaction [Dinitrofluorobenzene results in increased secretion of TSLP protein]
CTD
PMID:30183461
NCBI chr18:24,447,409...24,454,244
Ensembl chr18:24,449,844...24,453,548
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Txnrd1
thioredoxin reductase 1
increases expression
ISO
Dinitrofluorobenzene results in increased expression of TXNRD1 mRNA
CTD
PMID:23445166
NCBI chr 7:20,830,042...20,914,990
Ensembl chr 7:20,830,045...20,907,863
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Xcl1
X-C motif chemokine ligand 1
increases expression
ISO
Dinitrofluorobenzene results in increased expression of XCL1 mRNA
CTD
PMID:15719370
NCBI chr13:77,248,687...77,252,343
Ensembl chr13:77,248,717...77,252,329
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Zfp870
zinc finger protein 870
increases expression
ISO
Dinitrofluorobenzene results in increased expression of ZNF670 mRNA
CTD
PMID:23999411
NCBI chr 7:11,990,146...12,003,813
Ensembl chr 7:11,990,148...12,003,813
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Zxdb
zinc finger, X-linked, duplicated B
increases expression
ISO
Dinitrofluorobenzene results in increased expression of ZXDB mRNA
CTD
PMID:23999411
NCBI chr X:59,700,765...59,706,737
Ensembl chr X:59,701,178...59,703,871 Ensembl chr X:59,701,178...59,703,871
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