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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:quinolinium ion
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Accession:CHEBI:52837 term browser browse the term
Synonyms:related_synonym: quinolinium ions


show annotations for term's descendants           Sort by:
dequalinium term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase decreases activity ISO Dequalinium results in decreased activity of ACHE protein CTD PMID:33400519 NCBI chr12:25,042,882...25,050,608
Ensembl chr12:25,043,461...25,050,410 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 decreases expression ISO Dequalinium results in decreased expression of CCL2 protein CTD PMID:20116850 NCBI chr10:67,503,077...67,504,875
Ensembl chr10:67,503,077...67,504,875 		JBrowse link
G Ccl3 C-C motif chemokine ligand 3 decreases expression ISO Dequalinium results in decreased expression of CCL3 protein CTD PMID:20116850 NCBI chr10:68,948,889...68,950,439
Ensembl chr10:68,948,889...68,950,439 		JBrowse link
G Ccl4 C-C motif chemokine ligand 4 decreases expression ISO Dequalinium results in decreased expression of CCL4 protein CTD PMID:20116850 NCBI chr10:68,963,893...68,965,728
Ensembl chr10:68,950,289...68,965,722 		JBrowse link
G Ccl5 C-C motif chemokine ligand 5 decreases expression ISO Dequalinium results in decreased expression of CCL5 protein CTD PMID:20116850 NCBI chr10:68,820,330...68,824,906
Ensembl chr10:68,738,651...68,824,884 		JBrowse link
G Il6r interleukin 6 receptor decreases expression ISO Dequalinium results in decreased expression of IL6R protein modified form CTD PMID:20116850 NCBI chr 2:177,582,020...177,646,705
Ensembl chr 2:177,582,164...177,645,221 		JBrowse link
G Kcnn1 potassium calcium-activated channel subfamily N member 1 decreases activity ISO Dequalinium results in decreased activity of KCNN1 protein CTD PMID:10696100 NCBI chr16:18,608,782...18,632,571
Ensembl chr16:18,610,769...18,632,571 		JBrowse link
G Kcnn2 potassium calcium-activated channel subfamily N member 2 decreases activity EXP Dequalinium results in decreased activity of KCNN2 protein CTD PMID:10696100 NCBI chr18:40,004,693...40,445,043
Ensembl chr18:40,155,939...40,445,045 		JBrowse link
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO Dequalinium inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr 1:50,668,817...50,711,019
Ensembl chr 1:50,668,817...50,711,019 		JBrowse link
G Tp53 tumor protein p53 increases expression ISO Dequalinium results in increased expression of TP53 protein CTD PMID:21548882 NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299 		JBrowse link
G Vegfa vascular endothelial growth factor A decreases expression ISO Dequalinium results in decreased expression of VEGFA protein CTD PMID:20116850 NCBI chr 9:22,452,854...22,468,194
Ensembl chr 9:22,439,392...22,468,194 		JBrowse link
pyrvinium term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acta2 actin alpha 2, smooth muscle multiple interactions EXP pyrvinium inhibits the reaction [Glyburide promotes the reaction [Isoproterenol results in increased expression of ACTA2 protein]]; pyrvinium inhibits the reaction [Isoproterenol results in increased expression of ACTA2 protein] CTD PMID:35305975 NCBI chr 1:241,159,723...241,172,503
Ensembl chr 1:241,159,724...241,172,503 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 decreases phosphorylation ISO pyrvinium results in decreased phosphorylation of AKT1 protein CTD PMID:27542212 NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:137,535,390...137,552,610 		JBrowse link
G Axin2 axin 2 decreases expression ISO pyrvinium results in decreased expression of AXIN2 mRNA CTD PMID:21170416 NCBI chr10:94,393,379...94,426,579
Ensembl chr10:94,395,909...94,426,575 		JBrowse link
G Casp3 caspase 3 multiple interactions EXP pyrvinium inhibits the reaction [Glyburide promotes the reaction [Isoproterenol results in increased activity of CASP3 protein]]; pyrvinium inhibits the reaction [Isoproterenol results in increased activity of CASP3 protein] CTD PMID:35305975 NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732 		JBrowse link
G Cat catalase multiple interactions EXP pyrvinium inhibits the reaction [Glyburide promotes the reaction [Isoproterenol results in decreased activity of CAT protein]]; pyrvinium inhibits the reaction [Isoproterenol results in decreased activity of CAT protein] CTD PMID:35305975 NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:110,297,342...110,329,526 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 decreases expression ISO pyrvinium results in decreased expression of CCL2 protein CTD PMID:20116850 NCBI chr10:67,503,077...67,504,875
Ensembl chr10:67,503,077...67,504,875 		JBrowse link
G Ccne2 cyclin E2 multiple interactions ISO pyrvinium inhibits the reaction [PIK3CA protein modified form results in increased expression of CCNE2 mRNA] CTD PMID:27542212 NCBI chr 5:29,082,169...29,094,879
Ensembl chr 5:29,082,703...29,094,882 		JBrowse link
G Ccng2 cyclin G2 multiple interactions ISO pyrvinium inhibits the reaction [PIK3CA protein modified form results in decreased expression of CCNG2 mRNA] CTD PMID:27542212 NCBI chr14:15,088,694...15,097,190
Ensembl chr14:15,088,695...15,096,206 		JBrowse link
G Cdh1 cadherin 1 multiple interactions ISO pyrvinium inhibits the reaction [ROR2 protein results in decreased expression of CDH1 protein] CTD PMID:39428718 NCBI chr19:51,402,178...51,471,572
Ensembl chr19:51,402,034...51,471,565 		JBrowse link
G Cdh2 cadherin 2 multiple interactions ISO pyrvinium inhibits the reaction [ROR2 protein results in increased expression of CDH2 protein] CTD PMID:39428718 NCBI chr18:8,051,097...8,265,288
Ensembl chr18:8,051,097...8,265,288 		JBrowse link
G Csgalnact1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 multiple interactions ISO pyrvinium inhibits the reaction [PIK3CA protein modified form results in decreased expression of CSGALNACT1 mRNA] CTD PMID:27542212 NCBI chr16:25,761,946...26,097,306
Ensembl chr16:26,002,530...26,096,065 		JBrowse link
G Csnk1a1 casein kinase 1, alpha 1 decreases activity ISO pyrvinium results in decreased activity of CSNK1A1 protein CTD PMID:21170416 NCBI chr18:57,285,156...57,320,540
Ensembl chr18:57,287,412...57,320,538 		JBrowse link
G Ctnnb1 catenin beta 1 multiple interactions EXP
ISO 		pyrvinium inhibits the reaction [[Glyburide co-treated with Isoproterenol] results in increased expression of CTNNB1 mRNA]; pyrvinium inhibits the reaction [Glyburide promotes the reaction [Isoproterenol results in increased expression of CTNNB1 protein]]; pyrvinium inhibits the reaction [Isoproterenol results in increased expression of CTNNB1 mRNA]; pyrvinium inhibits the reaction [Isoproterenol results in increased expression of CTNNB1 protein]
pyrvinium results in decreased expression of and results in increased phosphorylation of CTNNB1 protein; ricinine inhibits the reaction [pyrvinium results in decreased expression of and results in increased phosphorylation of CTNNB1 protein] 		CTD PMID:25124862 PMID:35305975 NCBI chr 8:129,517,576...129,544,661
Ensembl chr 8:129,517,545...129,544,662 		JBrowse link
G Dkk1 dickkopf WNT signaling pathway inhibitor 1 decreases expression ISO pyrvinium results in decreased expression of DKK1 mRNA CTD PMID:21170416 NCBI chr 1:237,794,969...237,798,650
Ensembl chr 1:237,794,969...237,798,650 		JBrowse link
G Dscc1 DNA replication and sister chromatid cohesion 1 multiple interactions ISO pyrvinium inhibits the reaction [PIK3CA protein modified form results in increased expression of DSCC1 mRNA] CTD PMID:27542212 NCBI chr 7:88,372,349...88,390,815
Ensembl chr 7:88,372,146...88,387,973 		JBrowse link
G Endod1 endonuclease domain containing 1 multiple interactions ISO pyrvinium inhibits the reaction [PIK3CA protein modified form results in increased expression of ENDOD1 mRNA] CTD PMID:27542212 NCBI chr 8:19,490,615...19,520,007
Ensembl chr 8:19,490,615...19,520,007 		JBrowse link
G Fn1 fibronectin 1 multiple interactions EXP pyrvinium inhibits the reaction [Glyburide promotes the reaction [Isoproterenol results in increased expression of FN1 protein]]; pyrvinium inhibits the reaction [Isoproterenol results in increased expression of FN1 protein] CTD PMID:35305975 NCBI chr 9:80,645,507...80,714,200
Ensembl chr 9:80,645,507...80,714,137 		JBrowse link
G Gpr35 G protein-coupled receptor 35 multiple interactions ISO pyrvinium binds to and results in increased activity of GPR35 protein CTD PMID:20919992 NCBI chr 9:100,974,580...100,995,330
Ensembl chr 9:100,962,538...100,986,985 		JBrowse link
G Hbp1 HMG-box transcription factor 1 multiple interactions ISO pyrvinium inhibits the reaction [PIK3CA protein modified form results in decreased expression of HBP1 mRNA] CTD PMID:27542212 NCBI chr 6:54,257,118...54,283,373
Ensembl chr 6:54,256,864...54,283,366 		JBrowse link
G Hey1 hes-related family bHLH transcription factor with YRPW motif 1 multiple interactions ISO pyrvinium inhibits the reaction [PIK3CA protein modified form results in decreased expression of HEY1 mRNA] CTD PMID:27542212 NCBI chr 2:95,003,935...95,006,457
Ensembl chr 2:95,002,943...95,007,624 		JBrowse link
G Il17a interleukin 17A multiple interactions EXP pyrvinium inhibits the reaction [Glyburide promotes the reaction [Isoproterenol results in increased expression of IL17A protein]]; pyrvinium inhibits the reaction [Isoproterenol results in increased expression of IL17A protein] CTD PMID:35305975 NCBI chr 9:30,640,844...30,644,331
Ensembl chr 9:30,640,844...30,644,331 		JBrowse link
G Il1b interleukin 1 beta multiple interactions EXP pyrvinium inhibits the reaction [Glyburide promotes the reaction [Isoproterenol results in increased expression of IL1B protein]]; pyrvinium inhibits the reaction [Isoproterenol results in increased expression of IL1B protein] CTD PMID:35305975 NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601 		JBrowse link
G Il6 interleukin 6 decreases expression
decreases secretion 		ISO pyrvinium results in decreased expression of IL6 mRNA
pyrvinium results in decreased secretion of IL6 protein 		CTD PMID:33021119 NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610 		JBrowse link
G Il6r interleukin 6 receptor decreases expression ISO pyrvinium results in decreased expression of IL6R protein modified form CTD PMID:20116850 NCBI chr 2:177,582,020...177,646,705
Ensembl chr 2:177,582,164...177,645,221 		JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity ISO pyrvinium results in decreased activity of KCNH2 protein CTD PMID:28551711 NCBI chr 4:11,719,357...11,751,424
Ensembl chr 4:11,692,980...11,751,421 		JBrowse link
G Kmt2a lysine methyltransferase 2A multiple interactions ISO pyrvinium inhibits the reaction [KMT2A protein results in decreased susceptibility to molibresib] CTD PMID:26367796 NCBI chr 8:54,013,547...54,089,219
Ensembl chr 8:54,013,547...54,089,317 		JBrowse link
G Mpo myeloperoxidase multiple interactions EXP pyrvinium inhibits the reaction [Isoproterenol results in increased activity of MPO protein] CTD PMID:35305975 NCBI chr10:73,092,124...73,102,057
Ensembl chr10:73,092,400...73,102,056 		JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor decreases expression ISO pyrvinium results in decreased expression of MYC mRNA CTD PMID:21170416 NCBI chr 7:95,483,105...95,488,031
Ensembl chr 7:95,483,105...95,488,028 		JBrowse link
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha multiple interactions ISO pyrvinium inhibits the reaction [PIK3CA protein modified form results in decreased expression of CCNG2 mRNA]; pyrvinium inhibits the reaction [PIK3CA protein modified form results in decreased expression of CSGALNACT1 mRNA]; pyrvinium inhibits the reaction [PIK3CA protein modified form results in decreased expression of CXCL8 mRNA]; pyrvinium inhibits the reaction [PIK3CA protein modified form results in decreased expression of HBP1 mRNA]; pyrvinium inhibits the reaction [PIK3CA protein modified form results in decreased expression of HEY1 mRNA]; pyrvinium inhibits the reaction [PIK3CA protein modified form results in decreased expression of TGFA mRNA]; pyrvinium inhibits the reaction [PIK3CA protein modified form results in increased expression of CCNE2 mRNA]; pyrvinium inhibits the reaction [PIK3CA protein modified form results in increased expression of DSCC1 mRNA]; pyrvinium inhibits the reaction [PIK3CA protein modified form results in increased expression of ENDOD1 mRNA]; pyrvinium inhibits the reaction [PIK3CA protein modified form results in increased expression of PPP2R1B mRNA] CTD PMID:27542212 NCBI chr 2:117,103,643...117,177,411
Ensembl chr 2:117,143,468...117,177,411 		JBrowse link
G Ppp2r1b protein phosphatase 2 scaffold subunit A beta multiple interactions ISO pyrvinium inhibits the reaction [PIK3CA protein modified form results in increased expression of PPP2R1B mRNA] CTD PMID:27542212 NCBI chr 8:60,092,540...60,125,512
Ensembl chr 8:60,081,553...60,125,795 		JBrowse link
G Ror2 receptor tyrosine kinase-like orphan receptor 2 multiple interactions ISO pyrvinium inhibits the reaction [ROR2 protein results in decreased expression of CDH1 protein]; pyrvinium inhibits the reaction [ROR2 protein results in increased expression of CDH2 protein]; pyrvinium inhibits the reaction [ROR2 protein results in increased expression of VIM protein] CTD PMID:39428718 NCBI chr17:12,124,749...12,300,044
Ensembl chr17:12,124,749...12,300,044 		JBrowse link
G Rps6 ribosomal protein S6 decreases phosphorylation
affects phosphorylation 		ISO pyrvinium results in decreased phosphorylation of RPS6 protein
pyrvinium affects the phosphorylation of RPS6 protein 		CTD PMID:27542212 NCBI chr 5:106,417,680...106,420,540
Ensembl chr 5:106,417,680...106,420,566 		JBrowse link
G Rps6kb1 ribosomal protein S6 kinase B1 decreases phosphorylation ISO pyrvinium results in decreased phosphorylation of RPS6KB1 protein CTD PMID:27542212 NCBI chr10:71,817,794...71,865,211
Ensembl chr10:71,815,614...71,865,238 		JBrowse link
G Tgfa transforming growth factor alpha multiple interactions ISO pyrvinium inhibits the reaction [PIK3CA protein modified form results in decreased expression of TGFA mRNA] CTD PMID:27542212 NCBI chr 4:120,175,549...120,258,342
Ensembl chr 4:120,175,593...120,258,339 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions EXP pyrvinium inhibits the reaction [Glyburide promotes the reaction [Isoproterenol results in increased expression of TGFB1 protein]]; pyrvinium inhibits the reaction [Isoproterenol results in increased expression of TGFB1 protein] CTD PMID:35305975 NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:90,324,046...90,340,899 		JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP pyrvinium inhibits the reaction [Glyburide promotes the reaction [Isoproterenol results in increased expression of TNF protein]]; pyrvinium inhibits the reaction [Isoproterenol results in increased expression of TNF protein] CTD PMID:35305975 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303 		JBrowse link
G Tnni3 troponin I3, cardiac type multiple interactions EXP pyrvinium inhibits the reaction [Glyburide promotes the reaction [Isoproterenol results in increased expression of TNNI3 protein]]; pyrvinium inhibits the reaction [Isoproterenol results in increased expression of TNNI3 protein] CTD PMID:35305975 NCBI chr 1:78,342,571...78,346,255
Ensembl chr 1:78,342,592...78,346,253 		JBrowse link
G Vegfa vascular endothelial growth factor A decreases expression ISO pyrvinium results in decreased expression of VEGFA protein CTD PMID:20116850 NCBI chr 9:22,452,854...22,468,194
Ensembl chr 9:22,439,392...22,468,194 		JBrowse link
G Vim vimentin multiple interactions ISO pyrvinium inhibits the reaction [belinostat results in increased expression of VIM protein]; pyrvinium inhibits the reaction [ROR2 protein results in increased expression of VIM protein] CTD PMID:23671600 PMID:39428718 NCBI chr17:81,577,261...81,585,746
Ensembl chr17:81,568,272...81,585,746 		JBrowse link
G Wnt7a Wnt family member 7A decreases activity ISO pyrvinium results in decreased activity of WNT7A protein CTD PMID:25174399 NCBI chr 4:125,420,276...125,466,149
Ensembl chr 4:125,420,276...125,466,149 		JBrowse link
G Wwtr1 WW domain containing transcription regulator 1 multiple interactions ISO pyrvinium inhibits the reaction [belinostat results in increased expression of WWTR1 protein] CTD PMID:23671600 NCBI chr 2:143,801,181...143,916,941
Ensembl chr 2:143,801,181...143,991,950 		JBrowse link
Yo-Pro-1 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G P2rx7 purinergic receptor P2X 7 multiple interactions
increases uptake 		ISO Phenolsulfonphthalein inhibits the reaction [P2RX7 protein results in increased uptake of YO-PRO 1] CTD PMID:18942742 NCBI chr12:39,550,531...39,594,984
Ensembl chr12:39,540,567...39,595,193 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20874
    chemical entity 20872
      molecular entity 20871
        ion 17463
          organic ion 11556
            organic cation 9047
              quinolinium ion 50
                1,1'-[1,9-bis(dimethylammonio)nonane-1,9-diyl]bis\ 0
                4-[(3-carboxy-2-hydroxy-1-naphthalenyl)methyl]-3-hydroxy-2-naphthalenecarboxylic acid 2-[2-(2,5-dimethyl-1-phenyl-3-pyrrolyl)ethyl]-N,N,1-trimethyl-6-quinolin-1-iumamine 0
                LDS 751(1+) + 0
                LSM-36456 0
                To-Pro-1(2+) + 0
                To-Pro-3(2+) + 0
                ToTo-1(4+) + 0
                ToTo-3(4+) + 0
                UCL 1684 0
                Yo-Pro-1(2+) + 1
                Yo-Pro-3(2+) + 0
                YoYo-1(4+) + 0
                YoYo-3(4+) + 0
                chloroquine(2+) 0
                cryptocyanin cation + 0
                dequalinium + 11
                hydroxychloroquine(2+) 0
                lenvatinib(1+) + 0
                pinacyanol cation + 0
                pyrvinium 41
                thiazole orange cation + 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 20874
    subatomic particle 20883
      composite particle 20883
        hadron 20872
          baryon 20883
            nucleon 20872
              atomic nucleus 20883
                atom 20872
                  main group element atom 20796
                    main group molecular entity 20809
                      p-block molecular entity 20796
                        carbon group molecular entity 20724
                          organic molecular entity 20706
                            organic ion 11556
                              organic cation 9047
                                quinolinium ion 50
                                  1,1'-[1,9-bis(dimethylammonio)nonane-1,9-diyl]bis\ 0
                                  4-[(3-carboxy-2-hydroxy-1-naphthalenyl)methyl]-3-hydroxy-2-naphthalenecarboxylic acid 2-[2-(2,5-dimethyl-1-phenyl-3-pyrrolyl)ethyl]-N,N,1-trimethyl-6-quinolin-1-iumamine 0
                                  LDS 751(1+) + 0
                                  LSM-36456 0
                                  To-Pro-1(2+) + 0
                                  To-Pro-3(2+) + 0
                                  ToTo-1(4+) + 0
                                  ToTo-3(4+) + 0
                                  UCL 1684 0
                                  Yo-Pro-1(2+) + 1
                                  Yo-Pro-3(2+) + 0
                                  YoYo-1(4+) + 0
                                  YoYo-3(4+) + 0
                                  chloroquine(2+) 0
                                  cryptocyanin cation + 0
                                  dequalinium + 11
                                  hydroxychloroquine(2+) 0
                                  lenvatinib(1+) + 0
                                  pinacyanol cation + 0
                                  pyrvinium 41
                                  thiazole orange cation + 0
paths to the root