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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:2',7'-bis-(2-carboxyethyl)carboxyfluorescein
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Accession:CHEBI:52689 term browser browse the term
Definition:A carboxyfluorescein compound having two (2-carboxyethyl) substituents at the 2'- and 7'-positions on the xanthene portion.
Synonyms:related_synonym: 2',7'-bis-(2-carboxyethyl)carboxyfluoresceins
 xref_mesh: MESH:C043829


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2',7'-bis-(2-carboxyethyl)carboxyfluorescein term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc4 ATP binding cassette subfamily C member 4 multiple interactions ISO Mefloquine inhibits the reaction [ABCC4 protein affects the export of 2',7'-bis(carboxyethyl)-5(6)-carboxyfluorescein]; verlukast inhibits the reaction [ABCC4 protein affects the export of 2',7'-bis(carboxyethyl)-5(6)-carboxyfluorescein] CTD PMID:16004972 NCBI chr15:95,541,186...95,774,898
Ensembl chr15:95,542,315...95,774,283 		JBrowse link
G Abcc5 ATP binding cassette subfamily C member 5 increases export
multiple interactions		 ISO ABCC5 protein results in increased export of 2',7'-bis(carboxyethyl)-5(6)-carboxyfluorescein
daidzein inhibits the reaction [ABCC5 protein results in increased export of 2',7'-bis(carboxyethyl)-5(6)-carboxyfluorescein]; hesperetin inhibits the reaction [ABCC5 protein results in increased export of 2',7'-bis(carboxyethyl)-5(6)-carboxyfluorescein]; naringenin inhibits the reaction [ABCC5 protein results in increased export of 2',7'-bis(carboxyethyl)-5(6)-carboxyfluorescein]; Quercetin inhibits the reaction [ABCC5 protein results in increased export of 2',7'-bis(carboxyethyl)-5(6)-carboxyfluorescein]; resveratrol inhibits the reaction [ABCC5 protein results in increased export of 2',7'-bis(carboxyethyl)-5(6)-carboxyfluorescein]; Silymarin inhibits the reaction [ABCC5 protein results in increased export of 2',7'-bis(carboxyethyl)-5(6)-carboxyfluorescein]; verlukast inhibits the reaction [ABCC5 protein results in increased export of 2',7'-bis(carboxyethyl)-5(6)-carboxyfluorescein]		 CTD PMID:16156793 NCBI chr11:80,473,809...80,567,257
Ensembl chr11:80,473,872...80,567,253 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19901
    role 19871
      application 19716
        dye 3005
          xanthene dye 88
            2',7'-bis-(2-carboxyethyl)carboxyfluorescein 2
              2',7'-bis-(2-carboxyethyl)-5-carboxyfluorescein 0
              2',7'-bis-(2-carboxyethyl)-6-carboxyfluorescein 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19901
    subatomic particle 19899
      composite particle 19899
        hadron 19899
          baryon 19899
            nucleon 19899
              atomic nucleus 19899
                atom 19899
                  main group element atom 19838
                    p-block element atom 19838
                      carbon group element atom 19778
                        carbon atom 19775
                          organic molecular entity 19775
                            heteroorganic entity 19534
                              organochalcogen compound 19295
                                organooxygen compound 19211
                                  carbon oxoacid 18679
                                    carboxylic acid 18676
                                      aromatic carboxylic acid 12750
                                        benzoic acids 12728
                                          fluorescein (acid form) 69
                                            2',7'-bis-(2-carboxyethyl)carboxyfluorescein 2
                                              2',7'-bis-(2-carboxyethyl)-5-carboxyfluorescein 0
                                              2',7'-bis-(2-carboxyethyl)-6-carboxyfluorescein 0
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