The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
A member of the class of benzimidazoles that is 1H-benzimidazole substituted by a pyrrolidin-1-ylmethyl and a 4-chlorobenzyl groups at positions 2 and 1 respectively.
[clemizole co-treated with Cisplatin] results in decreased expression of CAT protein; clemizole inhibits the reaction [Cisplatin results in decreased expression of CAT protein]
clemizole results in increased expression of CYP2B6 mRNA [clemizole co-treated with NR1I3 protein alternative form] results in increased expression of CYP2B6 mRNA; [clemizole co-treated with NR1I3 protein mutant form] results in increased expression of CYP2B6 mRNA
clemizole results in increased expression of CYP3A4 mRNA [clemizole results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA
[clemizole co-treated with Cisplatin] results in increased expression of LCN2 protein; clemizole inhibits the reaction [Cisplatin results in increased expression of LCN2 protein]
clemizole promotes the reaction [NCOA1 protein binds to NR1I3 protein alternative form]; clemizole promotes the reaction [NCOA1 protein binds to NR1I3 protein]
[Cisplatin co-treated with clemizole] results in decreased expression of NPHS1 protein; clemizole inhibits the reaction [Cisplatin results in decreased expression of NPHS1 protein]
clemizole affects the localization of NR1I3 protein mutant form [clemizole co-treated with NR1I3 protein alternative form] results in increased expression of CYP2B6 mRNA; [clemizole co-treated with NR1I3 protein mutant form] results in increased expression of CYP2B6 mRNA; clemizole binds to and results in increased activity of NR1I3 protein alternative form; clemizole inhibits the reaction [ethyl (5-(diethylglycyl)-10,11-dihydro-5H-dibenzo(b,f)azepin-3-yl)carbamate results in decreased activity of NR1I3 protein]; clemizole promotes the reaction [MED1 protein binds to NR1I3 protein alternative form]; clemizole promotes the reaction [NCOA1 protein binds to NR1I3 protein alternative form]; clemizole promotes the reaction [NCOA1 protein binds to NR1I3 protein]; clemizole promotes the reaction [NCOA3 protein binds to NR1I3 protein] clemizole binds to NR1I3 protein
[Cisplatin co-treated with clemizole] results in decreased expression of SYNPO protein; clemizole inhibits the reaction [Cisplatin results in decreased expression of SYNPO protein]
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