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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:monohaloethene
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Accession:CHEBI:51313 term browser browse the term
Definition:A haloethene in which only one of the hydrogen atoms in ethene is replaced by a halogen atom.
Synonyms:related_synonym: haloethene;   monohaloethenes;   vinyl halide;   vinyl halides


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bromoethene term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 increases oxidation ISO CYP2E1 protein results in increased oxidation of vinyl bromide CTD PMID:1664256 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023 		JBrowse link
G H2ax H2A.X variant histone increases phosphorylation EXP vinyl bromide results in increased phosphorylation of H2AX protein CTD PMID:37527026 NCBI chr 8:44,671,907...44,673,262
Ensembl chr 8:44,671,786...44,673,239
Ensembl chr 4:44,671,786...44,673,239 		JBrowse link
G Mki67 marker of proliferation Ki-67 increases expression EXP vinyl bromide results in increased expression of MKI67 protein CTD PMID:37527026 NCBI chr 1:190,496,319...190,522,983
Ensembl chr 1:190,496,319...190,522,762 		JBrowse link
chloroethene term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcd3 ATP binding cassette subfamily D member 3 increases expression ISO Vinyl Chloride results in increased expression of ABCD3 mRNA CTD PMID:18579281 NCBI chr 2:209,852,087...209,905,763
Ensembl chr 2:209,852,087...209,906,020 		JBrowse link
G Acaca acetyl-CoA carboxylase alpha increases expression ISO Vinyl Chloride results in increased expression of ACACA mRNA; Vinyl Chloride results in increased expression of ACACA protein CTD PMID:31445928 NCBI chr10:69,014,261...69,276,453
Ensembl chr10:69,014,170...69,276,457 		JBrowse link
G Acer2 alkaline ceramidase 2 decreases expression ISO Vinyl Chloride results in decreased expression of ACER2 mRNA CTD PMID:18579281 NCBI chr 5:101,391,830...101,442,615
Ensembl chr 5:101,391,885...101,442,614 		JBrowse link
G Acly ATP citrate lyase increases expression ISO Vinyl Chloride metabolite results in increased expression of ACLY mRNA; Vinyl Chloride results in increased expression of ACLY mRNA CTD PMID:18579281 PMID:26962056 NCBI chr10:85,412,045...85,464,253
Ensembl chr10:85,412,049...85,463,320 		JBrowse link
G Acox1 acyl-CoA oxidase 1 multiple interactions ISO [Vinyl Chloride co-treated with Dietary Fats co-treated with Dietary Carbohydrates] results in decreased expression of ACOX1 mRNA CTD PMID:37061008 NCBI chr10:101,406,197...101,431,252
Ensembl chr10:101,406,197...101,431,232 		JBrowse link
G Acss2 acyl-CoA synthetase short-chain family member 2 increases expression ISO Vinyl Chloride results in increased expression of ACSS2 mRNA CTD PMID:18579281 NCBI chr 3:144,003,808...144,047,452
Ensembl chr 3:144,004,336...144,059,675 		JBrowse link
G Adgrb2 adhesion G protein-coupled receptor B2 increases expression ISO Vinyl Chloride results in increased expression of ADGRB2 mRNA CTD PMID:18579281 NCBI chr 5:142,299,190...142,362,540
Ensembl chr 5:142,331,329...142,362,540 		JBrowse link
G Adh4 alcohol dehydrogenase 4 (class II), pi polypeptide increases expression ISO Vinyl Chloride results in increased expression of ADH4 mRNA CTD PMID:18579281 NCBI chr 2:226,948,717...226,966,747
Ensembl chr 2:226,947,466...226,987,591 		JBrowse link
G Agk acylglycerol kinase increases expression ISO Vinyl Chloride results in increased expression of AGK mRNA CTD PMID:18579281 NCBI chr 4:69,114,850...69,193,989
Ensembl chr 4:69,114,269...69,193,934 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 increases phosphorylation
multiple interactions		 ISO Vinyl Chloride metabolite results in increased phosphorylation of AKT1 protein
Vinyl Chloride results in increased expression of and results in increased phosphorylation of AKT1 protein		 CTD PMID:26962056 PMID:36892438 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member increases response to substance ISO ALDH2 gene SNP results in increased susceptibility to Vinyl Chloride CTD PMID:20100738 NCBI chr12:34,949,549...34,982,527
Ensembl chr12:34,901,219...34,982,521 		JBrowse link
G Aldh3a1 aldehyde dehydrogenase 3 family, member A1 increases activity EXP Vinyl Chloride results in increased activity of ALDH3A1 protein CTD PMID:15211785 NCBI chr10:45,892,993...45,902,680
Ensembl chr10:45,892,924...45,902,681 		JBrowse link
G Alpi alkaline phosphatase, intestinal decreases expression ISO Vinyl Chloride results in decreased expression of ALPI mRNA CTD PMID:18579281 NCBI chr 9:87,773,411...87,776,877
Ensembl chr 9:87,773,411...87,776,877 		JBrowse link
G Angptl4 angiopoietin-like 4 decreases expression ISO Vinyl Chloride results in decreased expression of ANGPTL4 mRNA CTD PMID:18579281 NCBI chr 7:14,550,288...14,557,797
Ensembl chr 7:14,550,311...14,556,519 		JBrowse link
G Arhgef16 Rho guanine nucleotide exchange factor 16 increases expression ISO Vinyl Chloride results in increased expression of ARHGEF16 mRNA CTD PMID:18579281 NCBI chr 5:164,843,656...164,866,212
Ensembl chr 5:164,844,161...164,866,212 		JBrowse link
G Arsg arylsulfatase G increases expression ISO Vinyl Chloride results in increased expression of ARSG mRNA CTD PMID:18579281 NCBI chr10:94,412,261...94,551,224
Ensembl chr10:94,447,399...94,542,941 		JBrowse link
G Atl1 atlastin GTPase 1 increases expression ISO Vinyl Chloride results in increased expression of ATL1 mRNA CTD PMID:18579281 NCBI chr 6:88,377,168...88,475,242
Ensembl chr 6:88,377,239...88,475,204 		JBrowse link
G Bsg basigin decreases expression ISO Vinyl Chloride results in decreased expression of BSG mRNA CTD PMID:18579281 NCBI chr 7:9,993,170...10,000,387
Ensembl chr 7:9,993,170...10,000,387 		JBrowse link
G Car11 carbonic anhydrase 11 decreases expression ISO Vinyl Chloride results in decreased expression of CAR11 mRNA CTD PMID:18579281 NCBI chr 1:96,169,900...96,175,191
Ensembl chr 1:96,170,080...96,175,191 		JBrowse link
G Casp1 caspase 1 increases expression ISO Vinyl Chloride results in increased expression of CASP1 protein modified form CTD PMID:34717031 NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383 		JBrowse link
G Casp14 caspase 14 increases expression ISO Vinyl Chloride results in increased expression of CASP14 mRNA CTD PMID:18579281 NCBI chr 7:10,929,759...10,932,591
Ensembl chr 7:10,926,725...10,933,405 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions ISO [Dietary Fats co-treated with Vinyl Chloride] results in increased secretion of CCL2 protein; [Vinyl Chloride co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of CCL2 mRNA CTD PMID:31774537 PMID:34717031 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226 		JBrowse link
G Ccl3 C-C motif chemokine ligand 3 multiple interactions ISO [Dietary Fats co-treated with Vinyl Chloride] results in increased secretion of CCL3 protein CTD PMID:31774537 NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938 		JBrowse link
G Ccn3 cellular communication network factor 3 multiple interactions ISO [Dietary Fats co-treated with Vinyl Chloride] affects the expression of CCN3 protein CTD PMID:36892438 NCBI chr 7:86,094,000...86,101,022
Ensembl chr 7:86,094,000...86,101,019 		JBrowse link
G Ccnb1 cyclin B1 increases expression ISO Vinyl Chloride results in increased expression of CCNB1 mRNA CTD PMID:18579281 NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172 		JBrowse link
G Cd40 CD40 molecule increases expression ISO Vinyl Chloride results in increased expression of CD40 protein CTD PMID:36892438 NCBI chr 3:153,790,372...153,805,279
Ensembl chr 3:153,790,449...153,805,534 		JBrowse link
G Cd48 Cd48 molecule increases expression ISO Vinyl Chloride results in increased expression of CD48 protein CTD PMID:36892438 NCBI chr13:84,184,884...84,209,144
Ensembl chr13:84,185,532...84,209,142 		JBrowse link
G Cdh17 cadherin 17 increases expression ISO Vinyl Chloride results in increased expression of CDH17 mRNA CTD PMID:18579281 NCBI chr 5:25,262,820...25,314,884
Ensembl chr 5:25,262,758...25,314,884 		JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A affects response to substance ISO CDKN2A polymorphism affects the susceptibility to Vinyl Chloride CTD PMID:24464562 NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149 		JBrowse link
G Cenpe centromere protein E increases expression ISO Vinyl Chloride results in increased expression of CENPE mRNA CTD PMID:18579281 NCBI chr 2:223,637,035...223,695,692
Ensembl chr 2:223,636,998...223,695,669 		JBrowse link
G Chrna4 cholinergic receptor nicotinic alpha 4 subunit increases expression ISO Vinyl Chloride results in increased expression of CHRNA4 mRNA CTD PMID:18579281 NCBI chr 3:168,136,246...168,157,839
Ensembl chr 3:168,136,266...168,156,957 		JBrowse link
G Cirbp cold inducible RNA binding protein increases expression ISO Vinyl Chloride results in increased expression of CIRBP mRNA CTD PMID:18579281 NCBI chr 7:9,533,857...9,538,899
Ensembl chr 7:9,424,178...9,538,818 		JBrowse link
G Col15a1 collagen type XV alpha 1 chain increases expression ISO Vinyl Chloride results in increased expression of COL15A1 mRNA CTD PMID:18579281 NCBI chr 5:61,501,963...61,607,591
Ensembl chr 5:61,501,963...61,607,591 		JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A increases expression
multiple interactions		 ISO Vinyl Chloride metabolite results in increased expression of CPT1A mRNA
[Dietary Fats co-treated with Vinyl Chloride] results in increased expression of CPT1A protein		 CTD PMID:26962056 PMID:36892438 NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:200,565,613...200,627,055 		JBrowse link
G Cst3 cystatin C multiple interactions ISO [Dietary Fats co-treated with Vinyl Chloride] affects the expression of CST3 protein CTD PMID:36892438 NCBI chr 3:136,336,923...136,340,796
Ensembl chr 3:136,336,920...136,340,822 		JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 multiple interactions ISO [Dietary Fats co-treated with Vinyl Chloride] results in increased secretion of CXCL10 protein CTD PMID:31774537 NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975 		JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 multiple interactions ISO [Dietary Fats co-treated with Vinyl Chloride] results in increased secretion of CXCL2 protein CTD PMID:31774537 NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075 		JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions
increases oxidation
affects response to substance
increases activity
affects metabolic processing
increases metabolic processing
increases response to substance		 ISO
EXP		 CYP2E1 gene polymorphism promotes the reaction [Vinyl Chloride affects the mutagenesis of KRAS gene]; CYP2E1 gene polymorphism promotes the reaction [Vinyl Chloride affects the mutagenesis of TP53 gene]; CYP2E1 gene polymorphism promotes the reaction [Vinyl Chloride results in increased mutagenesis of KRAS gene]; CYP2E1 gene polymorphism promotes the reaction [Vinyl Chloride results in increased mutagenesis of TP53 gene]
CYP2E1 protein results in increased oxidation of Vinyl Chloride
CYP2E1 gene polymorphism affects the susceptibility to Vinyl Chloride
Vinyl Chloride results in increased activity of CYP2E1 protein
1,2-dichloroethylene inhibits the reaction [CYP2E1 protein affects the metabolism of Vinyl Chloride]
CYP2E1 protein results in increased metabolism of Vinyl Chloride
CYP2E1 gene polymorphism results in increased susceptibility to Vinyl Chloride; CYP2E1 gene SNP results in increased susceptibility to Vinyl Chloride		 CTD PMID:1664256 PMID:7871537 PMID:12010862 PMID:12705718 PMID:15211785 More... NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023 		JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 decreases expression ISO Vinyl Chloride results in decreased expression of CYP3A13 mRNA CTD PMID:18579281 NCBI chr12:16,806,222...16,846,428
Ensembl chr12:16,806,207...16,846,422 		JBrowse link
G Dcn decorin increases expression ISO Vinyl Chloride results in increased expression of DCN protein CTD PMID:36892438 NCBI chr 7:32,281,252...32,321,291
Ensembl chr 7:32,281,252...32,321,270 		JBrowse link
G Dkk3 dickkopf WNT signaling pathway inhibitor 3 decreases expression ISO Vinyl Chloride results in decreased expression of DKK3 mRNA CTD PMID:18579281 NCBI chr 1:166,237,969...166,281,271
Ensembl chr 1:166,238,238...166,280,590 		JBrowse link
G Dusp8 dual specificity phosphatase 8 increases expression ISO Vinyl Chloride results in increased expression of DUSP8 mRNA CTD PMID:18579281 NCBI chr 1:197,167,392...197,184,285
Ensembl chr 1:197,169,422...197,182,921 		JBrowse link
G Eepd1 endonuclease/exonuclease/phosphatase family domain containing 1 increases expression ISO Vinyl Chloride results in increased expression of EEPD1 mRNA CTD PMID:18579281 NCBI chr 8:23,957,258...24,064,343
Ensembl chr 8:23,957,255...24,064,340 		JBrowse link
G Ercc2 ERCC excision repair 2, TFIIH core complex helicase subunit increases response to substance ISO ERCC2 gene SNP results in increased susceptibility to Vinyl Chloride CTD PMID:18420361 NCBI chr 1:79,033,342...79,047,102
Ensembl chr 1:79,033,326...79,047,102 		JBrowse link
G Ercc4 ERCC excision repair 4, endonuclease catalytic subunit affects response to substance ISO ERCC4 5' UTR SNP affects the susceptibility to Vinyl Chloride CTD PMID:21216194 NCBI chr10:2,416,259...2,448,364
Ensembl chr10:2,419,038...2,448,369
Ensembl chr10:2,419,038...2,448,369 		JBrowse link
G Far1 fatty acyl CoA reductase 1 decreases expression ISO Vinyl Chloride results in decreased expression of FAR1 mRNA CTD PMID:18579281 NCBI chr 1:167,644,622...167,705,868
Ensembl chr 1:167,644,677...167,705,730 		JBrowse link
G Fasn fatty acid synthase increases expression ISO Vinyl Chloride results in increased expression of FASN mRNA; Vinyl Chloride results in increased expression of FASN protein CTD PMID:31445928 NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261 		JBrowse link
G Fbxo41 F-box protein 41 increases expression ISO Vinyl Chloride results in increased expression of FBXO41 mRNA CTD PMID:18579281 NCBI chr 4:118,007,517...118,039,547
Ensembl chr 4:118,010,978...118,039,406 		JBrowse link
G Fcgr2b Fc gamma receptor 2B decreases expression ISO Vinyl Chloride results in decreased expression of FCGR2B protein CTD PMID:36892438 NCBI chr13:83,191,253...83,207,778
Ensembl chr13:83,193,163...83,207,778 		JBrowse link
G Fdps farnesyl diphosphate synthase increases expression ISO Vinyl Chloride results in increased expression of FDPS mRNA CTD PMID:18579281 NCBI chr 2:174,497,402...174,507,031
Ensembl chr 2:174,486,665...174,507,776 		JBrowse link
G Fkbp5 FKBP prolyl isomerase 5 decreases expression ISO Vinyl Chloride results in decreased expression of FKBP5 mRNA CTD PMID:18579281 NCBI chr20:6,457,207...6,575,404
Ensembl chr20:6,457,216...6,541,674 		JBrowse link
G Folr1 folate receptor alpha increases expression ISO Vinyl Chloride results in increased expression of FOLR1 mRNA CTD PMID:18579281 NCBI chr 1:156,219,460...156,238,436
Ensembl chr 1:156,219,460...156,230,667 		JBrowse link
G G0s2 G0/G1switch 2 decreases expression ISO Vinyl Chloride results in decreased expression of G0S2 mRNA CTD PMID:18579281 NCBI chr13:104,806,351...104,807,263
Ensembl chr13:104,806,156...104,807,451 		JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha affects response to substance ISO GADD45A polymorphism affects the susceptibility to Vinyl Chloride CTD PMID:24464562 NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115 		JBrowse link
G Gbp6 guanylate binding protein family member 6 increases expression ISO Vinyl Chloride results in increased expression of GBP9 mRNA CTD PMID:18579281 NCBI chr14:4,730,286...4,756,508
Ensembl chr14:4,730,453...4,839,062
Ensembl chr14:4,730,453...4,839,062 		JBrowse link
G Gde1 glycerophosphodiester phosphodiesterase 1 decreases expression ISO Vinyl Chloride results in decreased expression of GDE1 mRNA CTD PMID:18579281 NCBI chr 1:173,016,984...173,032,396
Ensembl chr 1:172,954,394...173,032,429 		JBrowse link
G Gmppb GDP-mannose pyrophosphorylase B increases expression ISO Vinyl Chloride results in increased expression of GMPPB mRNA CTD PMID:18579281 NCBI chr 8:108,737,429...108,740,437
Ensembl chr 8:108,693,060...108,767,286 		JBrowse link
G Gnb5 G protein subunit beta 5 increases expression ISO Vinyl Chloride results in increased expression of GNB5 mRNA CTD PMID:18579281 NCBI chr 8:76,076,120...76,105,069
Ensembl chr 8:76,073,306...76,105,069 		JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1 decreases expression
multiple interactions		 ISO Vinyl Chloride results in decreased expression of GOT1 mRNA
[Vinyl Chloride co-treated with Dietary Fats co-treated with Dietary Carbohydrates] results in increased activity of GOT1 protein		 CTD PMID:18579281 PMID:37061008 NCBI chr 1:242,357,293...242,381,535
Ensembl chr 1:242,357,306...242,380,633 		JBrowse link
G Gpa33 glycoprotein A33 increases expression ISO Vinyl Chloride results in increased expression of GPA33 mRNA CTD PMID:18579281 NCBI chr13:78,381,141...78,414,765
Ensembl chr13:78,381,141...78,414,765 		JBrowse link
G Gpam glycerol-3-phosphate acyltransferase, mitochondrial increases expression ISO Vinyl Chloride results in increased expression of GPAM mRNA CTD PMID:18579281 NCBI chr 1:254,106,323...254,170,755
Ensembl chr 1:254,106,331...254,142,639 		JBrowse link
G Gpr85 G protein-coupled receptor 85 decreases expression ISO Vinyl Chloride results in decreased expression of GPR85 mRNA CTD PMID:18579281 NCBI chr 4:42,100,138...42,109,584
Ensembl chr 4:42,102,941...42,109,566 		JBrowse link
G Gpt glutamic--pyruvic transaminase increases expression
multiple interactions		 ISO Vinyl Chloride results in increased expression of GPT protein
[Vinyl Chloride co-treated with Dietary Fats co-treated with Dietary Carbohydrates] results in increased activity of GPT protein		 CTD PMID:31445928 PMID:37061008 NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494 		JBrowse link
G Gramd1c GRAM domain containing 1C increases expression ISO Vinyl Chloride results in increased expression of GRAMD1C mRNA CTD PMID:18579281 NCBI chr11:56,633,229...56,718,570
Ensembl chr11:56,633,227...56,718,570 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta increases expression
multiple interactions		 ISO Vinyl Chloride metabolite results in increased expression of GSK3B mRNA
Vinyl Chloride results in increased expression of and results in increased phosphorylation of GSK3B protein		 CTD PMID:26962056 PMID:36892438 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646 		JBrowse link
G Gstm1 glutathione S-transferase mu 1 multiple interactions
increases expression		 ISO [GSTM1 gene polymorphism co-treated with GSTT1 gene polymorphism] results in increased susceptibility to Vinyl Chloride; GSTM1 gene polymorphism affects the reaction [XRCC1 gene polymorphism affects the reaction [Vinyl Chloride affects the mutagenesis of TP53 gene]]
Vinyl Chloride results in increased expression of GSTM1 protein		 CTD PMID:16097394 PMID:16977343 PMID:36892438 NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411 		JBrowse link
G Gstp1 glutathione S-transferase pi 1 increases response to substance
affects response to substance		 ISO GSTP1 gene SNP results in increased susceptibility to Vinyl Chloride
GSTP1 gene polymorphism affects the susceptibility to Vinyl Chloride		 CTD PMID:20100738 PMID:20134343 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226 		JBrowse link
G Gstt1 glutathione S-transferase theta 1 multiple interactions
increases response to substance		 ISO [GSTM1 gene polymorphism co-treated with GSTT1 gene polymorphism] results in increased susceptibility to Vinyl Chloride; GSTT1 gene polymorphism affects the reaction [XRCC1 gene polymorphism affects the reaction [Vinyl Chloride affects the mutagenesis of TP53 gene]]
GSTT1 gene polymorphism results in increased susceptibility to Vinyl Chloride		 CTD PMID:16097394 PMID:16270392 PMID:16977343 NCBI chr20:12,856,613...12,873,586
Ensembl chr20:12,856,669...12,873,585 		JBrowse link
G Hmox1 heme oxygenase 1 decreases expression ISO Vinyl Chloride results in decreased expression of HMOX1 mRNA; Vinyl Chloride results in decreased expression of HMOX1 protein CTD PMID:18579281 PMID:34717031 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Hoxc8 homeobox C8 increases expression ISO Vinyl Chloride results in increased expression of HOXC8 mRNA CTD PMID:18579281 NCBI chr 7:134,127,937...134,130,503
Ensembl chr 7:134,127,913...134,130,503 		JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 increases expression ISO Vinyl Chloride results in increased expression of HSPA5 mRNA CTD PMID:31445928 NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891 		JBrowse link
G Hspb8 heat shock protein family B (small) member 8 decreases expression ISO Vinyl Chloride results in decreased expression of HSPB8 mRNA CTD PMID:18579281 NCBI chr12:40,176,405...40,205,002
Ensembl chr12:40,176,532...40,191,185 		JBrowse link
G Hsph1 heat shock protein family H (Hsp110) member 1 decreases expression ISO Vinyl Chloride results in decreased expression of HSPH1 mRNA CTD PMID:18579281 NCBI chr12:5,390,916...5,410,224
Ensembl chr12:5,390,922...5,410,224 		JBrowse link
G Ifng interferon gamma multiple interactions
decreases expression		 ISO [Dietary Fats co-treated with Vinyl Chloride] results in increased secretion of IFNG protein
Vinyl Chloride results in decreased expression of IFNG mRNA		 CTD PMID:31774537 PMID:34717031 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375 		JBrowse link
G Igf1 insulin-like growth factor 1 increases expression ISO Vinyl Chloride results in increased expression of IGF1 protein CTD PMID:36892438 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296 		JBrowse link
G Igfbp3 insulin-like growth factor binding protein 3 decreases expression
multiple interactions		 ISO Vinyl Chloride results in decreased expression of IGFBP3 protein
[Dietary Fats co-treated with Vinyl Chloride] affects the expression of IGFBP3 protein		 CTD PMID:36892438 NCBI chr14:82,056,347...82,064,083
Ensembl chr14:82,056,347...82,064,083 		JBrowse link
G Ihh Indian hedgehog signaling molecule increases expression ISO Vinyl Chloride results in increased expression of IHH mRNA CTD PMID:18579281 NCBI chr 9:76,504,315...76,510,532
Ensembl chr 9:76,504,315...76,510,532 		JBrowse link
G Ikbke inhibitor of nuclear factor kappa B kinase subunit epsilon increases expression ISO Vinyl Chloride results in increased expression of IKBKE mRNA CTD PMID:18579281 NCBI chr13:42,712,154...42,738,470
Ensembl chr13:42,712,159...42,737,143 		JBrowse link
G Il10 interleukin 10 multiple interactions ISO Vinyl Chloride metabolite promotes the reaction [Lipopolysaccharides results in increased expression of IL10 mRNA] CTD PMID:26962056 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313 		JBrowse link
G Il18 interleukin 18 decreases expression ISO Vinyl Chloride results in decreased expression of IL18 mRNA CTD PMID:34717031 NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887 		JBrowse link
G Il1b interleukin 1 beta multiple interactions
decreases expression		 ISO Vinyl Chloride metabolite promotes the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]
Vinyl Chloride results in decreased expression of IL1B mRNA		 CTD PMID:26962056 PMID:34717031 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il1r1 interleukin 1 receptor type 1 decreases expression ISO Vinyl Chloride results in decreased expression of IL1R1 mRNA CTD PMID:18579281 NCBI chr 9:42,504,917...42,580,958
Ensembl chr 9:42,504,735...42,579,937 		JBrowse link
G Il36a interleukin 36, alpha increases expression ISO Vinyl Chloride results in increased expression of IL36A mRNA CTD PMID:18579281 NCBI chr 3:6,996,851...7,001,400
Ensembl chr 3:6,996,851...7,001,400 		JBrowse link
G Il6 interleukin 6 multiple interactions
decreases expression		 ISO Vinyl Chloride metabolite promotes the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]
Vinyl Chloride results in decreased expression of IL6 mRNA		 CTD PMID:26962056 PMID:34717031 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Impact impact RWD domain protein decreases expression ISO Vinyl Chloride results in decreased expression of IMPACT mRNA CTD PMID:18579281 NCBI chr18:4,108,872...4,147,571
Ensembl chr18:4,108,853...4,147,569 		JBrowse link
G Insig1 insulin induced gene 1 increases expression ISO Vinyl Chloride results in increased expression of INSIG1 mRNA CTD PMID:18579281 NCBI chr 4:7,315,494...7,323,972
Ensembl chr 4:7,315,495...7,323,952 		JBrowse link
G Kel Kell metallo-endopeptidase (Kell blood group) increases expression ISO Vinyl Chloride results in increased expression of KEL mRNA CTD PMID:18579281 NCBI chr 4:70,568,241...70,585,666
Ensembl chr 4:70,568,243...70,585,631 		JBrowse link
G Klhl31 kelch-like family member 31 increases expression ISO Vinyl Chloride results in increased expression of KLHL31 mRNA CTD PMID:18579281 NCBI chr 8:78,515,514...78,538,873
Ensembl chr 8:78,515,514...78,538,873 		JBrowse link
G Kras KRAS proto-oncogene, GTPase multiple interactions
increases mutagenesis
increases response to substance		 ISO CYP2E1 gene polymorphism promotes the reaction [Vinyl Chloride affects the mutagenesis of KRAS gene]; CYP2E1 gene polymorphism promotes the reaction [Vinyl Chloride results in increased mutagenesis of KRAS gene]; XRCC1 gene polymorphism promotes the reaction [Vinyl Chloride results in increased mutagenesis of KRAS gene]
KRAS gene polymorphism results in increased susceptibility to Vinyl Chloride		 CTD PMID:10629081 PMID:11563603 PMID:12211074 PMID:12670519 PMID:12705718 More... NCBI chr 4:178,185,418...178,218,484 JBrowse link
G Larp1 La ribonucleoprotein 1, translational regulator multiple interactions ISO [Vinyl Chloride co-treated with Dietary Fats co-treated with Dietary Carbohydrates] results in decreased expression of LARP1 mRNA CTD PMID:37061008 NCBI chr10:42,191,378...42,246,361
Ensembl chr10:42,191,325...42,243,371 		JBrowse link
G Lpar4 lysophosphatidic acid receptor 4 decreases expression ISO Vinyl Chloride results in decreased expression of LPAR4 mRNA CTD PMID:18579281 NCBI chr  X:72,033,486...72,046,978
Ensembl chr  X:72,033,486...72,046,977 		JBrowse link
G Lrrc49 leucine rich repeat containing 49 decreases expression ISO Vinyl Chloride results in decreased expression of LRRC49 mRNA CTD PMID:18579281 NCBI chr 8:61,053,264...61,160,695
Ensembl chr 8:61,053,267...61,160,850 		JBrowse link
G Lrtm1 leucine-rich repeats and transmembrane domains 1 increases expression ISO Vinyl Chloride results in increased expression of LRTM1 mRNA CTD PMID:18579281 NCBI chr16:4,210,343...4,217,843 JBrowse link
G Map3k5 mitogen-activated protein kinase kinase kinase 5 decreases expression ISO Vinyl Chloride results in decreased expression of MAP3K5 mRNA CTD PMID:18579281 NCBI chr 1:14,685,776...14,904,935
Ensembl chr 1:14,685,492...14,904,800 		JBrowse link
G Mapk8ip2 mitogen-activated protein kinase 8 interacting protein 2 increases expression ISO Vinyl Chloride results in increased expression of MAPK8IP2 mRNA CTD PMID:18579281 NCBI chr 7:120,526,732...120,536,982
Ensembl chr 7:120,526,732...120,536,982 		JBrowse link
G Mcf2l MCF.2 cell line derived transforming sequence-like increases expression ISO Vinyl Chloride results in increased expression of MCF2L mRNA CTD PMID:18579281 NCBI chr16:76,507,133...76,652,893
Ensembl chr16:76,507,133...76,652,733 		JBrowse link
G Mdm2 MDM2 proto-oncogene affects response to substance ISO MDM2 polymorphism affects the susceptibility to Vinyl Chloride CTD PMID:24464562 NCBI chr 7:53,290,660...53,315,205
Ensembl chr 7:53,290,664...53,314,915 		JBrowse link
G Me1 malic enzyme 1 increases expression ISO Vinyl Chloride results in increased expression of ME1 mRNA CTD PMID:18579281 NCBI chr 8:87,549,043...87,660,251
Ensembl chr 8:87,549,043...87,660,304 		JBrowse link
G Med1 mediator complex subunit 1 decreases expression ISO Vinyl Chloride results in decreased expression of MED1 mRNA CTD PMID:18579281 NCBI chr10:83,145,538...83,189,260
Ensembl chr10:83,145,568...83,189,299 		JBrowse link
G Meis1 Meis homeobox 1 increases expression ISO Vinyl Chloride results in increased expression of MEIS1 mRNA CTD PMID:18579281 NCBI chr14:93,155,426...93,294,373
Ensembl chr14:93,155,419...93,294,265 		JBrowse link
G Mgmt O-6-methylguanine-DNA methyltransferase decreases expression EXP Vinyl Chloride results in decreased expression of MGMT protein CTD PMID:15256147 NCBI chr 1:191,710,980...191,937,760
Ensembl chr 1:191,710,930...191,937,756 		JBrowse link
G Mid1ip1 MID1 interacting protein 1 increases expression ISO Vinyl Chloride results in increased expression of MID1IP1 mRNA CTD PMID:18579281 NCBI chr  X:12,060,993...12,063,318
Ensembl chr  X:12,060,883...12,065,774 		JBrowse link
G Mki67 marker of proliferation Ki-67 multiple interactions ISO [Vinyl Chloride co-treated with Dietary Fats co-treated with Dietary Carbohydrates] results in increased expression of MKI67 protein CTD PMID:37061008 NCBI chr 1:190,496,319...190,522,983
Ensembl chr 1:190,496,319...190,522,762 		JBrowse link
G Mlxipl MLX interacting protein-like multiple interactions
increases expression		 ISO [Vinyl Chloride co-treated with Dietary Fats co-treated with Dietary Carbohydrates] results in increased expression of MLXIPL mRNA
Vinyl Chloride results in increased expression of MLXIPL mRNA		 CTD PMID:37061008 NCBI chr12:21,541,608...21,577,120
Ensembl chr12:21,543,576...21,577,112 		JBrowse link
G Mpdz multiple PDZ domain crumbs cell polarity complex component increases expression ISO Vinyl Chloride results in increased expression of MPDZ mRNA CTD PMID:18579281 NCBI chr 5:95,766,112...95,920,531
Ensembl chr 5:95,766,118...95,920,499 		JBrowse link
G Mpg N-methylpurine-DNA glycosylase increases expression EXP Vinyl Chloride analog results in increased expression of MPG mRNA CTD PMID:10882851 NCBI chr10:15,396,246...15,402,528
Ensembl chr10:15,395,782...15,402,520 		JBrowse link
G Mt1 metallothionein 1 decreases expression ISO Vinyl Chloride results in decreased expression of MT1 mRNA CTD PMID:18579281 NCBI chr19:10,826,032...10,827,048
Ensembl chr19:10,826,032...10,827,049
Ensembl chr17:10,826,032...10,827,049
Ensembl chr  X:10,826,032...10,827,049 		JBrowse link
G Mt4 metallothionein 4 decreases expression ISO Vinyl Chloride results in decreased expression of MT4 mRNA CTD PMID:18579281 NCBI chr19:10,863,813...10,865,909
Ensembl chr19:10,863,813...10,865,909 		JBrowse link
G Mtor mechanistic target of rapamycin kinase increases phosphorylation ISO Vinyl Chloride metabolite results in increased phosphorylation of MTOR protein CTD PMID:26962056 NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311 		JBrowse link
G Mvd mevalonate diphosphate decarboxylase increases expression ISO Vinyl Chloride results in increased expression of MVD mRNA CTD PMID:18579281 NCBI chr19:50,496,366...50,506,429
Ensembl chr19:50,496,367...50,507,971 		JBrowse link
G Mycn MYCN proto-oncogene, bHLH transcription factor increases expression
multiple interactions		 ISO Vinyl Chloride results in increased expression of MYCN mRNA
[Vinyl Chloride co-treated with Dietary Fats co-treated with Dietary Carbohydrates] results in increased expression of MYCN mRNA		 CTD PMID:37061008 NCBI chr 6:35,717,764...35,723,590
Ensembl chr 6:35,717,764...35,723,590 		JBrowse link
G Nefl neurofilament light chain increases expression ISO Vinyl Chloride results in increased expression of NEFL mRNA CTD PMID:18579281 NCBI chr15:42,301,920...42,305,793
Ensembl chr15:42,301,916...42,305,793 		JBrowse link
G Niban2 niban apoptosis regulator 2 increases expression ISO Vinyl Chloride results in increased expression of NIBAN2 mRNA CTD PMID:18579281 NCBI chr 3:16,174,674...16,224,293
Ensembl chr 3:16,174,659...16,224,293 		JBrowse link
G Nip7 nucleolar pre-rRNA processing protein NIP7 decreases expression ISO Vinyl Chloride results in decreased expression of NIP7 mRNA CTD PMID:18579281 NCBI chr19:34,962,557...34,964,700
Ensembl chr19:34,962,557...34,964,711 		JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO Vinyl Chloride metabolite promotes the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA] CTD PMID:26962056 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210 		JBrowse link
G Olfml2b olfactomedin-like 2B increases expression ISO Vinyl Chloride results in increased expression of OLFML2B mRNA CTD PMID:18579281 NCBI chr13:82,869,414...82,906,607
Ensembl chr13:82,869,433...82,906,607 		JBrowse link
G Or5b99 olfactory receptor family 5 subfamily B member 99 increases expression ISO Vinyl Chloride results in increased expression of OR5B99 mRNA CTD PMID:18579281 NCBI chr 1:210,136,841...210,137,767
Ensembl chr 1:210,132,946...210,138,365 		JBrowse link
G Pck1 phosphoenolpyruvate carboxykinase 1 decreases expression
increases expression		 ISO Vinyl Chloride results in decreased expression of PCK1 mRNA
Vinyl Chloride metabolite results in increased expression of PCK1 mRNA		 CTD PMID:18579281 PMID:26962056 NCBI chr 3:161,930,256...161,936,205
Ensembl chr 3:161,930,256...161,936,191 		JBrowse link
G Pcna proliferating cell nuclear antigen multiple interactions ISO [Vinyl Chloride co-treated with Dietary Fats co-treated with Dietary Carbohydrates] results in increased expression of PCNA protein CTD PMID:37061008 NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995 		JBrowse link
G Pcsk9 proprotein convertase subtilisin/kexin type 9 increases expression ISO Vinyl Chloride results in increased expression of PCSK9 mRNA CTD PMID:18579281 NCBI chr 5:121,211,278...121,233,688
Ensembl chr 5:121,211,278...121,233,688 		JBrowse link
G Pfkp phosphofructokinase, platelet decreases expression ISO Vinyl Chloride results in decreased expression of PFKP mRNA CTD PMID:18579281 NCBI chr17:63,729,743...63,794,026
Ensembl chr17:63,729,780...63,794,018 		JBrowse link
G Pkd1l2 polycystin 1 like 2 decreases expression ISO Vinyl Chloride results in decreased expression of PKD1L2 mRNA CTD PMID:18579281 NCBI chr19:45,049,713...45,136,503
Ensembl chr19:45,049,719...45,135,532 		JBrowse link
G Plch2 phospholipase C, eta 2 increases expression ISO Vinyl Chloride results in increased expression of PLCH2 mRNA CTD PMID:18579281 NCBI chr 5:165,544,209...165,613,769
Ensembl chr 5:165,544,200...165,602,356 		JBrowse link
G Plin4 perilipin 4 decreases expression ISO Vinyl Chloride results in decreased expression of PLIN4 mRNA CTD PMID:18579281 NCBI chr 9:929,168...938,062
Ensembl chr 9:929,176...938,056 		JBrowse link
G Pnliprp2 pancreatic lipase related protein 2 increases expression ISO Vinyl Chloride results in increased expression of PNLIPRP2 mRNA CTD PMID:18579281 NCBI chr 1:257,897,766...257,916,434
Ensembl chr 1:257,897,766...257,916,434 		JBrowse link
G Pole2 DNA polymerase epsilon 2, accessory subunit increases expression ISO Vinyl Chloride results in increased expression of POLE2 mRNA CTD PMID:18579281 NCBI chr 6:87,674,702...87,712,723
Ensembl chr 6:87,674,702...87,699,305 		JBrowse link
G Postn periostin increases expression ISO Vinyl Chloride results in increased expression of POSTN protein CTD PMID:36892438 NCBI chr 2:138,527,714...138,559,098
Ensembl chr 2:138,527,696...138,559,099 		JBrowse link
G Ppp1r3g protein phosphatase 1, regulatory subunit 3G decreases expression ISO Vinyl Chloride results in decreased expression of PPP1R3G mRNA CTD PMID:18579281 NCBI chr17:28,874,956...28,878,288
Ensembl chr17:28,876,482...28,877,525 		JBrowse link
G Prok1 prokineticin 1 increases expression ISO Vinyl Chloride results in increased expression of PROK1 mRNA CTD PMID:18579281 NCBI chr 2:194,850,539...194,859,343
Ensembl chr 2:194,853,991...194,859,250 		JBrowse link
G Psat1 phosphoserine aminotransferase 1 increases expression ISO Vinyl Chloride results in increased expression of PSAT1 mRNA CTD PMID:18579281 NCBI chr 1:213,196,709...213,218,564
Ensembl chr 1:213,196,709...213,218,682 		JBrowse link
G Pthlh parathyroid hormone-like hormone increases response to substance ISO PTHLH gene polymorphism results in increased susceptibility to Vinyl Chloride CTD PMID:12807761 NCBI chr 4:180,188,792...180,199,847
Ensembl chr 4:180,188,792...180,199,847 		JBrowse link
G Ptp4a1 protein tyrosine phosphatase 4A1 decreases expression ISO Vinyl Chloride results in decreased expression of PTP4A1 mRNA CTD PMID:18579281 NCBI chr 9:33,214,201...33,245,046
Ensembl chr 9:33,214,208...33,221,964 		JBrowse link
G Raet1l retinoic acid early transcript 1L increases expression ISO Vinyl Chloride results in increased expression of RAET1D mRNA CTD PMID:18579281 NCBI chr 1:1,979,433...1,984,410
Ensembl chr 1:1,979,443...1,984,410 		JBrowse link
G Retreg1 reticulophagy regulator 1 decreases expression ISO Vinyl Chloride results in decreased expression of RETREG1 mRNA CTD PMID:18579281 NCBI chr 2:76,335,609...76,474,817
Ensembl chr 2:76,335,609...76,493,898 		JBrowse link
G Rftn1 raftlin lipid raft linker 1 increases expression ISO Vinyl Chloride results in increased expression of RFTN1 mRNA CTD PMID:18579281 NCBI chr 9:10,804,611...11,002,084
Ensembl chr 9:10,804,611...11,002,084 		JBrowse link
G Rpl39l1 ribosomal protein L39 like 1 increases expression ISO Vinyl Chloride results in increased expression of RPL39L mRNA CTD PMID:18579281 NCBI chr10:5,455,712...5,459,828
Ensembl chr10:5,454,559...5,462,029 		JBrowse link
G S100a10 S100 calcium binding protein A10 increases expression ISO Vinyl Chloride results in increased expression of S100A10 mRNA CTD PMID:18579281 NCBI chr 2:179,221,012...179,229,659
Ensembl chr 2:179,220,887...179,229,661 		JBrowse link
G S100a9 S100 calcium binding protein A9 decreases expression ISO Vinyl Chloride results in decreased expression of S100A9 mRNA CTD PMID:18579281 NCBI chr 2:176,190,361...176,193,182
Ensembl chr 2:176,190,361...176,193,230 		JBrowse link
G Serpina12 serpin family A member 12 increases expression ISO Vinyl Chloride results in increased expression of SERPINA12 mRNA CTD PMID:18579281 NCBI chr 6:122,952,552...122,967,271
Ensembl chr 6:122,952,552...122,967,271 		JBrowse link
G Serpine2 serpin family E member 2 multiple interactions ISO Vinyl Chloride metabolite promotes the reaction [Lipopolysaccharides results in increased expression of SERPINE2 mRNA] CTD PMID:26962056 NCBI chr 9:81,124,746...81,188,866
Ensembl chr 9:81,124,804...81,188,826 		JBrowse link
G Shisa2 shisa family member 2 increases expression ISO Vinyl Chloride results in increased expression of SHISA2 mRNA CTD PMID:18579281 NCBI chr15:33,806,715...33,811,013
Ensembl chr15:33,805,958...33,811,013 		JBrowse link
G Slc2a4 solute carrier family 2 member 4 increases expression ISO Vinyl Chloride metabolite results in increased expression of SLC2A4 mRNA CTD PMID:26962056 NCBI chr10:54,666,015...54,671,581
Ensembl chr10:54,666,015...54,671,565 		JBrowse link
G Slc36a2 solute carrier family 36 member 2 increases expression ISO Vinyl Chloride results in increased expression of SLC36A2 mRNA CTD PMID:18579281 NCBI chr10:39,278,002...39,306,082
Ensembl chr10:39,278,046...39,306,082 		JBrowse link
G Slc39a14 solute carrier family 39 member 14 decreases expression ISO Vinyl Chloride results in decreased expression of SLC39A14 mRNA CTD PMID:18579281 NCBI chr15:45,376,806...45,423,549
Ensembl chr15:45,376,917...45,423,524 		JBrowse link
G Smim3 small integral membrane protein 3 increases expression ISO Vinyl Chloride results in increased expression of SMIM3 mRNA CTD PMID:18579281 NCBI chr18:53,930,019...53,982,339
Ensembl chr18:53,930,020...53,957,416 		JBrowse link
G Socs3 suppressor of cytokine signaling 3 decreases expression ISO Vinyl Chloride results in decreased expression of SOCS3 mRNA CTD PMID:18579281 NCBI chr10:103,193,909...103,197,322
Ensembl chr10:103,193,537...103,197,787 		JBrowse link
G Sod3 superoxide dismutase 3 decreases expression ISO Vinyl Chloride results in decreased expression of SOD3 protein CTD PMID:34717031 NCBI chr14:58,610,104...58,615,845
Ensembl chr14:58,609,958...58,615,990 		JBrowse link
G Sorbs3 sorbin and SH3 domain containing 3 decreases expression ISO Vinyl Chloride results in decreased expression of SORBS3 mRNA CTD PMID:18579281 NCBI chr15:45,252,921...45,284,758
Ensembl chr15:45,253,379...45,284,758 		JBrowse link
G Spon2 spondin 2 increases expression ISO Vinyl Chloride results in increased expression of SPON2 mRNA CTD PMID:18579281 NCBI chr14:77,505,695...77,518,001
Ensembl chr14:77,511,901...77,517,996 		JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 increases expression ISO Vinyl Chloride results in increased expression of SREBF1 mRNA CTD PMID:18579281 NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650 		JBrowse link
G St3gal5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 decreases expression ISO Vinyl Chloride results in decreased expression of ST3GAL5 mRNA CTD PMID:18579281 NCBI chr 4:104,134,613...104,192,558
Ensembl chr 4:104,134,613...104,192,558 		JBrowse link
G Tacc2 transforming, acidic coiled-coil containing protein 2 decreases expression ISO Vinyl Chloride results in decreased expression of TACC2 mRNA CTD PMID:18579281 NCBI chr 1:185,139,223...185,327,881
Ensembl chr 1:185,116,111...185,327,881 		JBrowse link
G Tango2 transport and golgi organization 2 homolog decreases expression ISO Vinyl Chloride results in decreased expression of TANGO2 mRNA CTD PMID:18579281 NCBI chr11:82,645,978...82,692,574
Ensembl chr11:82,645,974...82,692,574 		JBrowse link
G Tbc1d8 TBC1 domain family, member 8 decreases expression ISO Vinyl Chloride results in decreased expression of TBC1D8 mRNA CTD PMID:18579281 NCBI chr 9:41,651,394...41,761,432
Ensembl chr 9:41,651,395...41,761,409 		JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO [Dietary Fats co-treated with Vinyl Chloride] results in increased expression of TNF mRNA; [Dietary Fats co-treated with Vinyl Chloride] results in increased secretion of TNF protein CTD PMID:31774537 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tom1l2 target of myb1 like 2 membrane trafficking protein decreases expression ISO Vinyl Chloride results in decreased expression of TOM1L2 mRNA CTD PMID:18579281 NCBI chr10:45,036,034...45,158,168
Ensembl chr10:45,036,035...45,158,032 		JBrowse link
G Top2a DNA topoisomerase II alpha increases activity ISO Vinyl Chloride metabolite results in increased activity of TOP2A protein CTD PMID:15751973 NCBI chr10:83,945,731...83,976,874
Ensembl chr10:83,945,735...83,976,874 		JBrowse link
G Tp53 tumor protein p53 multiple interactions
affects response to substance
decreases expression
increases expression
increases mutagenesis
increases response to substance		 ISO CYP2E1 gene polymorphism promotes the reaction [Vinyl Chloride affects the mutagenesis of TP53 gene]; CYP2E1 gene polymorphism promotes the reaction [Vinyl Chloride results in increased mutagenesis of TP53 gene]; GSTM1 gene polymorphism affects the reaction [XRCC1 gene polymorphism affects the reaction [Vinyl Chloride affects the mutagenesis of TP53 gene]]; GSTT1 gene polymorphism affects the reaction [XRCC1 gene polymorphism affects the reaction [Vinyl Chloride affects the mutagenesis of TP53 gene]]; XRCC1 gene polymorphism affects the reaction [Vinyl Chloride affects the mutagenesis of TP53 gene]; XRCC1 gene polymorphism promotes the reaction [Vinyl Chloride affects the mutagenesis of TP53 gene]; XRCC1 gene polymorphism promotes the reaction [Vinyl Chloride results in increased mutagenesis of TP53 gene]
TP53 polymorphism affects the susceptibility to Vinyl Chloride
Vinyl Chloride results in decreased expression of TP53 mRNA
Vinyl Chloride results in increased expression of TP53 protein; Vinyl Chloride results in increased expression of TP53 protein mutant form
TP53 gene SNP results in increased susceptibility to Vinyl Chloride		 CTD PMID:12010862 PMID:12670519 PMID:12705718 PMID:14602524 PMID:14979067 More... NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
G Tp53inp1 tumor protein p53 inducible nuclear protein 1 decreases expression ISO Vinyl Chloride results in decreased expression of TRP53INP1 mRNA CTD PMID:18579281 NCBI chr 5:24,253,986...24,272,250
Ensembl chr 5:24,260,568...24,267,968 		JBrowse link
G Traf2 Tnf receptor-associated factor 2 increases expression ISO Vinyl Chloride results in increased expression of TRAF2 mRNA CTD PMID:18579281 NCBI chr 3:8,341,950...8,366,609
Ensembl chr 3:8,341,951...8,366,538 		JBrowse link
G Tsc22d1 TSC22 domain family, member 1 increases expression ISO Vinyl Chloride results in increased expression of TSC22D1 mRNA CTD PMID:18579281 NCBI chr15:51,750,489...51,850,958
Ensembl chr15:51,749,510...51,850,958 		JBrowse link
G Ttc23 tetratricopeptide repeat domain 23 increases expression ISO Vinyl Chloride results in increased expression of TTC23 mRNA CTD PMID:18579281 NCBI chr 1:121,245,996...121,329,500
Ensembl chr 1:121,248,084...121,329,494 		JBrowse link
G Ust uronyl-2-sulfotransferase increases expression ISO Vinyl Chloride results in increased expression of UST mRNA CTD PMID:18579281 NCBI chr 1:2,666,983...2,962,276
Ensembl chr 1:2,669,592...2,962,044 		JBrowse link
G Vamp1 vesicle-associated membrane protein 1 decreases expression ISO Vinyl Chloride results in decreased expression of VAMP1 mRNA CTD PMID:18579281 NCBI chr 4:158,012,634...158,019,350
Ensembl chr 4:158,012,663...158,019,349 		JBrowse link
G Vangl2 VANGL planar cell polarity protein 2 increases expression ISO Vinyl Chloride results in increased expression of VANGL2 mRNA CTD PMID:18579281 NCBI chr13:84,462,731...84,489,404
Ensembl chr13:84,465,527...84,489,378 		JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions ISO Vinyl Chloride metabolite inhibits the reaction [Lipopolysaccharides results in increased expression of VEGFA mRNA] CTD PMID:26962056 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641 		JBrowse link
G Veph1 ventricular zone expressed PH domain-containing 1 increases expression ISO Vinyl Chloride results in increased expression of VEPH1 mRNA CTD PMID:18579281 NCBI chr 2:150,291,379...150,537,491
Ensembl chr 2:150,296,573...150,537,266 		JBrowse link
G Wbp1l WW domain binding protein 1-like decreases expression ISO Vinyl Chloride results in decreased expression of WBP1L mRNA CTD PMID:18579281 NCBI chr 1:245,472,292...245,528,627
Ensembl chr 1:245,472,296...245,528,627 		JBrowse link
G Xpa XPA, DNA damage recognition and repair factor affects response to substance ISO XPA gene polymorphism affects the susceptibility to Vinyl Chloride CTD PMID:21216194 NCBI chr 5:60,431,673...60,475,726
Ensembl chr 5:60,431,673...60,475,726 		JBrowse link
G Xpc XPC complex subunit, DNA damage recognition and repair factor affects response to substance ISO XPC gene polymorphism affects the susceptibility to Vinyl Chloride CTD PMID:21216194 NCBI chr 4:123,993,670...124,020,922
Ensembl chr 4:123,993,666...124,021,010 		JBrowse link
G Xrcc1 X-ray repair cross complementing 1 multiple interactions
increases response to substance
decreases expression		 ISO
EXP		 GSTM1 gene polymorphism affects the reaction [XRCC1 gene polymorphism affects the reaction [Vinyl Chloride affects the mutagenesis of TP53 gene]]; GSTT1 gene polymorphism affects the reaction [XRCC1 gene polymorphism affects the reaction [Vinyl Chloride affects the mutagenesis of TP53 gene]]; XRCC1 gene polymorphism affects the reaction [Vinyl Chloride affects the mutagenesis of TP53 gene]; XRCC1 gene polymorphism promotes the reaction [Vinyl Chloride affects the mutagenesis of TP53 gene]; XRCC1 gene polymorphism promotes the reaction [Vinyl Chloride results in increased mutagenesis of KRAS gene]; XRCC1 gene polymorphism promotes the reaction [Vinyl Chloride results in increased mutagenesis of TP53 gene]
XRCC1 gene SNP results in increased susceptibility to Vinyl Chloride
Vinyl Chloride results in decreased expression of XRCC1 protein		 CTD PMID:12010862 PMID:14602524 PMID:15256147 PMID:16097394 PMID:16881598 More... NCBI chr 1:80,140,495...80,168,705
Ensembl chr 1:80,141,207...80,168,701 		JBrowse link
G Xrcc2 X-ray repair cross complementing 2 affects response to substance ISO XRCC2 gene polymorphism affects the susceptibility to Vinyl Chloride CTD PMID:16217922 NCBI chr 4:9,423,873...9,502,980
Ensembl chr 4:9,423,898...9,442,482 		JBrowse link
G Xrcc3 X-ray repair cross complementing 3 increases expression EXP Vinyl Chloride results in increased expression of XRCC3 protein CTD PMID:15256147 NCBI chr 6:130,863,405...130,873,765
Ensembl chr 6:130,863,959...130,872,444 		JBrowse link
G Ypel1 yippee-like 1 increases expression ISO Vinyl Chloride results in increased expression of YPEL1 mRNA CTD PMID:18579281 NCBI chr11:83,921,799...83,936,409 JBrowse link
G Zhx3 zinc fingers and homeoboxes 3 decreases expression ISO Vinyl Chloride results in decreased expression of ZHX3 mRNA CTD PMID:18579281 NCBI chr 3:149,417,787...149,548,671
Ensembl chr 3:149,417,818...149,527,079 		JBrowse link
fluoroethene term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions
affects oxidation		 ISO
EXP		 [fomepizole results in decreased activity of CYP2E1 protein] which results in decreased metabolism of vinyl fluoride
CYP2E1 protein affects the oxidation of vinyl fluoride
[fomepizole results in decreased activity of CYP2E1 protein] which results in decreased uptake of vinyl fluoride
[Ethanol results in increased activity of CYP2E1 protein] which results in increased metabolism of vinyl fluoride; [fomepizole results in decreased activity of CYP2E1 protein] which results in decreased uptake of vinyl fluoride		 CTD PMID:9073601 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023 		JBrowse link
G Mpg N-methylpurine-DNA glycosylase increases expression EXP vinyl fluoride results in increased expression of MPG mRNA CTD PMID:10882851 NCBI chr10:15,396,246...15,402,528
Ensembl chr10:15,395,782...15,402,520 		JBrowse link
G Srd5a1 steroid 5 alpha-reductase 1 decreases activity ISO vinyl fluoride analog results in decreased activity of SRD5A1 protein CTD PMID:8689240 NCBI chr 1:33,686,069...33,720,468
Ensembl chr 1:33,686,391...33,720,461 		JBrowse link
G Srd5a2 steroid 5 alpha-reductase 2 decreases activity ISO vinyl fluoride analog results in decreased activity of SRD5A2 protein CTD PMID:8689240 NCBI chr 6:21,426,225...21,465,727
Ensembl chr 6:21,426,215...21,462,112 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19901
    role 19871
      application 19716
        refrigerant 18307
          ethene 7707
            haloethene 7705
              monohaloethene 178
                bromoethene 3
                chloroethene 175
                fluoroethene 4
                iodoethene 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19901
    subatomic particle 19899
      composite particle 19899
        hadron 19899
          baryon 19899
            nucleon 19899
              atomic nucleus 19899
                atom 19899
                  main group element atom 19838
                    main group molecular entity 19838
                      s-block molecular entity 19672
                        hydrogen molecular entity 19654
                          hydrides 19163
                            organic hydride 18708
                              organic fundamental parent 18708
                                hydrocarbon 18457
                                  olefin 8940
                                    acyclic olefin 8778
                                      alkene 7856
                                        ethene 7707
                                          haloethene 7705
                                            monohaloethene 178
                                              bromoethene 3
                                              chloroethene 175
                                              fluoroethene 4
                                              iodoethene 0
paths to the root