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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:organic halide salt
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Accession:CHEBI:51069 term browser browse the term
Synonyms:related_synonym: organic halide salts



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(1R,3S)-3-(adamantan-1-yl)-1-(aminomethyl)-3,4-dihydroisochromene-5,6-diol hydrochloride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Drd1 dopamine receptor D1 multiple interactions
affects localization
ISO A 77636 binds to and results in increased activity of DRD1 protein; SCH 23390 inhibits the reaction [A 77636 affects the localization of DRD1 protein]; SCH 23390 inhibits the reaction [A 77636 results in increased activity of DRD1 protein] CTD PMID:15985612 NCBI chr13:54,205,202...54,209,677
Ensembl chr13:54,205,202...54,209,724
JBrowse link
(S)-duloxetine hydrochloride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 thymoma viral proto-oncogene 1 multiple interactions ISO Duloxetine Hydrochloride inhibits the reaction [Indomethacin results in decreased phosphorylation of AKT1 protein] CTD PMID:38701902 NCBI chr12:112,620,260...112,641,266
Ensembl chr12:112,620,255...112,641,318
JBrowse link
G Ar androgen receptor multiple interactions ISO Duloxetine Hydrochloride binds to and results in decreased activity of AR protein CTD PMID:25752796 NCBI chr  X:97,192,363...97,366,824
Ensembl chr  X:97,192,375...97,366,821
JBrowse link
G Cd48 CD48 antigen multiple interactions ISO Duloxetine Hydrochloride inhibits the reaction [Indomethacin results in increased expression of CD48 protein] CTD PMID:38701902 NCBI chr 1:171,508,989...171,532,825
Ensembl chr 1:171,509,577...171,532,826
JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 multiple interactions
decreases activity
ISO Duloxetine Hydrochloride inhibits the reaction [[CYP17A1 protein results in increased hydroxylation of Pregnenolone] which results in increased chemical synthesis of 17-alpha-Hydroxypregnenolone]; Duloxetine Hydrochloride inhibits the reaction [[CYP17A1 protein results in increased hydroxylation of Progesterone] which results in increased chemical synthesis of 17-alpha-Hydroxyprogesterone]; Duloxetine Hydrochloride inhibits the reaction [[CYP17A1 protein results in increased metabolism of 17-alpha-Hydroxypregnenolone] which results in increased chemical synthesis of Dehydroepiandrosterone]; Duloxetine Hydrochloride inhibits the reaction [[CYP17A1 protein results in increased metabolism of 17-alpha-Hydroxyprogesterone] which results in increased chemical synthesis of Androstenedione]; Duloxetine Hydrochloride inhibits the reaction [CYP17A1 protein results in increased hydroxylation of Pregnenolone]; Duloxetine Hydrochloride inhibits the reaction [CYP17A1 protein results in increased hydroxylation of Progesterone]; Duloxetine Hydrochloride inhibits the reaction [CYP17A1 protein results in increased metabolism of 17-alpha-Hydroxypregnenolone]; Duloxetine Hydrochloride inhibits the reaction [CYP17A1 protein results in increased metabolism of 17-alpha-Hydroxyprogesterone]
Duloxetine Hydrochloride results in decreased activity of CYP17A1 protein
CTD PMID:29100959 NCBI chr19:46,655,604...46,661,439
Ensembl chr19:46,655,604...46,661,611
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 decreases activity ISO Duloxetine Hydrochloride results in decreased activity of CYP1A1 protein CTD PMID:33814510 NCBI chr 9:57,595,211...57,611,107
Ensembl chr 9:57,595,211...57,611,107
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions ISO [furafylline results in decreased activity of CYP1A2 protein] which results in decreased glutathionylation of Duloxetine Hydrochloride; CYP1A2 protein results in increased activity of and results in increased glutathionylation of Duloxetine Hydrochloride CTD PMID:20669986 NCBI chr 9:57,584,220...57,590,938
Ensembl chr 9:57,584,220...57,590,986
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 decreases activity ISO Duloxetine Hydrochloride results in decreased activity of CYP1B1 protein CTD PMID:33814510 NCBI chr17:80,014,369...80,022,490
Ensembl chr17:80,008,966...80,022,490
JBrowse link
G Cyp2d22 cytochrome P450, family 2, subfamily d, polypeptide 22 multiple interactions ISO [Quinidine results in decreased activity of CYP2D6 protein] which results in decreased glutathionylation of Duloxetine Hydrochloride; CYP2D6 protein results in increased activity of and results in increased glutathionylation of Duloxetine Hydrochloride CTD PMID:20669986 NCBI chr15:82,254,728...82,264,461
Ensembl chr15:82,254,728...82,264,461
JBrowse link
G Hmox1 heme oxygenase 1 increases expression ISO Duloxetine Hydrochloride results in increased expression of HMOX1 mRNA CTD PMID:29134401 NCBI chr 8:75,820,246...75,827,221
Ensembl chr 8:75,820,249...75,827,217
JBrowse link
G Il1a interleukin 1 alpha multiple interactions ISO Duloxetine Hydrochloride inhibits the reaction [Indomethacin results in increased expression of IL1A protein] CTD PMID:38701902 NCBI chr 2:129,141,530...129,151,892
Ensembl chr 2:129,141,530...129,151,892
JBrowse link
G Kcnh2 potassium voltage-gated channel, subfamily H (eag-related), member 2 decreases activity ISO Duloxetine Hydrochloride results in decreased activity of KCNH2 protein CTD PMID:28551711 NCBI chr 5:24,524,583...24,556,671
Ensembl chr 5:24,524,587...24,556,602
JBrowse link
G Kcnj3 potassium inwardly-rectifying channel, subfamily J, member 3 multiple interactions EXP Duloxetine Hydrochloride results in decreased activity of [KCNJ3 mRNA co-treated with KCNJ5 mRNA]; Duloxetine Hydrochloride results in decreased activity of [KCNJ3 mRNA co-treated with KCNJ6 mRNA] CTD PMID:22164246 NCBI chr 2:55,301,814...55,488,157
Ensembl chr 2:55,325,982...55,488,157
JBrowse link
G Kcnj5 potassium inwardly-rectifying channel, subfamily J, member 5 multiple interactions EXP Duloxetine Hydrochloride results in decreased activity of [KCNJ3 mRNA co-treated with KCNJ5 mRNA] CTD PMID:22164246 NCBI chr 9:32,226,002...32,255,640
Ensembl chr 9:32,226,003...32,255,646
JBrowse link
G Kcnj6 potassium inwardly-rectifying channel, subfamily J, member 6 multiple interactions EXP Duloxetine Hydrochloride results in decreased activity of [KCNJ3 mRNA co-treated with KCNJ6 mRNA] CTD PMID:22164246 NCBI chr16:94,545,839...94,798,719
Ensembl chr16:94,549,495...94,798,560
JBrowse link
G Nfe2l2 nuclear factor, erythroid derived 2, like 2 affects localization ISO Duloxetine Hydrochloride affects the localization of NFE2L2 protein CTD PMID:29134401 NCBI chr 2:75,505,860...75,535,007
Ensembl chr 2:75,505,857...75,534,985
JBrowse link
G Prl prolactin increases expression ISO Duloxetine Hydrochloride results in increased expression of PRL protein CTD PMID:17606668 NCBI chr13:27,241,553...27,249,187
Ensembl chr13:27,241,553...27,249,188
JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions ISO Duloxetine Hydrochloride inhibits the reaction [Indomethacin results in decreased expression of VEGFA protein] CTD PMID:38701902 NCBI chr17:46,327,919...46,343,303
Ensembl chr17:46,327,919...46,343,295
JBrowse link
1,1-dimethyl-4-phenylpiperazinium iodide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chrna2 cholinergic receptor nicotinic alpha 2 subunit multiple interactions ISO Dimethylphenylpiperazinium Iodide results in increased activity of [CHRNB4 protein binds to CHRNA2 protein]
1,1-dimethyl-4-phenylpiperazinium iodide affects binding competes with [Epibatidine binds to Chrna2 protein]
CTD
RGD
PMID:9454827 PMID:15016836 RGD:2303194 NCBI chr14:66,370,685...66,390,397
Ensembl chr14:66,372,488...66,390,397
JBrowse link
G Chrna3 cholinergic receptor, nicotinic, alpha polypeptide 3 multiple interactions ISO Dimethylphenylpiperazinium Iodide results in increased activity of [CHRNB4 protein binds to CHRNA3 protein]
1,1-dimethyl-4-phenylpiperazinium iodide affects binding [Epibatidine binds to Chrna3 protein]
CTD
RGD
PMID:9454827 PMID:15016836 RGD:2303194 NCBI chr 9:54,917,401...54,933,846
Ensembl chr 9:54,917,395...54,933,846
JBrowse link
G Chrna4 cholinergic receptor, nicotinic, alpha polypeptide 4 multiple interactions ISO Dimethylphenylpiperazinium Iodide inhibits the reaction [epibatidine binds to [CHRNA4 protein binds to CHRNB2 protein]]; Dimethylphenylpiperazinium Iodide results in increased activity of [CHRNA4 protein binds to CHRNB2 protein]; Dimethylphenylpiperazinium Iodide results in increased activity of [CHRNB4 protein binds to CHRNA4 protein]
1,1-dimethyl-4-phenylpiperazinium iodide affects binding to Chrna4 protein; 1,1-dimethyl-4-phenylpiperazinium iodide competes with [Epibatidine binds to Chrna4 protein]
CTD
RGD
PMID:9454827 PMID:14645658 PMID:15016836 RGD:2303194 NCBI chr 2:180,664,104...180,685,339
Ensembl chr 2:180,660,173...180,685,339
JBrowse link
G Chrna7 cholinergic receptor, nicotinic, alpha polypeptide 7 multiple interactions
increases response to substance
increases activity
ISO Dimethylphenylpiperazinium Iodide inhibits the reaction [Bungarotoxins binds to CHRNA7 protein]
CHRNA7 protein mutant form results in increased susceptibility to Dimethylphenylpiperazinium Iodide
Dimethylphenylpiperazinium Iodide results in increased activity of CHRNA7 protein
CTD PMID:10082212 PMID:10216184 NCBI chr 7:62,748,440...62,862,274
Ensembl chr 7:62,748,440...62,862,317
JBrowse link
G Chrnb2 cholinergic receptor nicotinic beta 2 subunit multiple interactions ISO Dimethylphenylpiperazinium Iodide inhibits the reaction [epibatidine binds to [CHRNA4 protein binds to CHRNB2 protein]]; Dimethylphenylpiperazinium Iodide results in increased activity of [CHRNA4 protein binds to CHRNB2 protein]
1,1-dimethyl-4-phenylpiperazinium iodide affects binding to Chrnb2 protein; 1,1-dimethyl-4-phenylpiperazinium iodide competes with [Epibatidine binds to Chrnb2 protein]
CTD
RGD
PMID:14645658 PMID:15016836 RGD:2303194 NCBI chr 3:89,660,755...89,671,939
Ensembl chr 3:89,653,502...89,671,939
JBrowse link
G Chrnb4 cholinergic receptor, nicotinic, beta polypeptide 4 multiple interactions ISO Dimethylphenylpiperazinium Iodide results in increased activity of [CHRNB4 protein binds to CHRNA2 protein]; Dimethylphenylpiperazinium Iodide results in increased activity of [CHRNB4 protein binds to CHRNA3 protein]; Dimethylphenylpiperazinium Iodide results in increased activity of [CHRNB4 protein binds to CHRNA4 protein] CTD PMID:9454827 NCBI chr 9:54,935,438...54,956,236
Ensembl chr 9:54,935,438...54,956,063
JBrowse link
G Tnf tumor necrosis factor increases activity ISO TNF results in increased activity of Dimethylphenylpiperazinium Iodide CTD PMID:15086448 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983
JBrowse link
3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP-binding cassette, sub-family B member 1A decreases activity ISO thiazolyl blue results in decreased activity of ABCB1 protein CTD PMID:15451006 NCBI chr 5:8,617,091...8,798,575
Ensembl chr 5:8,710,077...8,798,575
JBrowse link
G Aco2 aconitase 2, mitochondrial multiple interactions EXP [Calcium results in increased activity of ACO2 protein] which results in increased reduction of thiazolyl blue; [Potassium deficiency results in decreased activity of ACO2 protein] which results in decreased reduction of thiazolyl blue CTD PMID:12548706 NCBI chr15:81,756,664...81,799,338
Ensembl chr15:81,756,510...81,799,334
JBrowse link
G Casp3 caspase 3 increases activity ISO thiazolyl blue results in increased activity of CASP3 protein CTD PMID:22401948 NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724
JBrowse link
G Casp8 caspase 8 increases activity ISO thiazolyl blue results in increased activity of CASP8 protein CTD PMID:22401948 NCBI chr 1:58,834,553...58,886,663
Ensembl chr 1:58,834,533...58,886,662
JBrowse link
G Nqo2 N-ribosyldihydronicotinamide quinone reductase 2 multiple interactions
increases reduction
ISO resveratrol inhibits the reaction [NQO2 protein results in increased reduction of thiazolyl blue]; Tacrine inhibits the reaction [NQO2 protein results in increased reduction of thiazolyl blue] CTD PMID:29281794 NCBI chr13:34,148,642...34,172,448
Ensembl chr13:34,148,670...34,172,426
JBrowse link
3beta-(2-diethylaminoethoxy)androst-5-en-17-one hydrochloride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gpc1 glypican 1 decreases degradation EXP 3-beta-(2-(diethylamino)ethoxy)androst-5-en-17-one results in decreased degradation of GPC1 protein CTD PMID:21642435 NCBI chr 1:92,759,367...92,787,933
Ensembl chr 1:92,759,367...92,788,501
JBrowse link
G Il1b interleukin 1 beta multiple interactions EXP 3-beta-(2-(diethylamino)ethoxy)androst-5-en-17-one inhibits the reaction [[Lipopolysaccharides results in increased susceptibility to Silicon Dioxide] which results in increased secretion of IL1B protein] CTD PMID:36860548 NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059
JBrowse link
4-fluoro-N-\{2-[4-(7-methoxynaphthalen-1-yl)piperazin-1-yl]ethyl\}benzamide hydrochloride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Htr1a 5-hydroxytryptamine (serotonin) receptor 1A multiple interactions ISO [1-((4-fluorobenzoylamino)ethyl)-4-(7-methoxy-1-naphthyl)piperazine hydrochloride binds to and results in increased activity of HTR1A protein] which results in decreased susceptibility to 1-(3-chlorophenyl)piperazine; [1-((4-fluorobenzoylamino)ethyl)-4-(7-methoxy-1-naphthyl)piperazine hydrochloride binds to and results in increased activity of HTR1A protein] which results in decreased susceptibility to Apomorphine; [1-((4-fluorobenzoylamino)ethyl)-4-(7-methoxy-1-naphthyl)piperazine hydrochloride binds to and results in increased activity of HTR1A protein] which results in decreased susceptibility to Physostigmine; tertatolol inhibits the reaction [[1-((4-fluorobenzoylamino)ethyl)-4-(7-methoxy-1-naphthyl)piperazine hydrochloride binds to and results in increased activity of HTR1A protein] which results in decreased susceptibility to Apomorphine]; tertatolol inhibits the reaction [[1-((4-fluorobenzoylamino)ethyl)-4-(7-methoxy-1-naphthyl)piperazine hydrochloride binds to and results in increased activity of HTR1A protein] which results in decreased susceptibility to Physostigmine] CTD PMID:8539317 NCBI chr13:105,580,040...105,584,630
Ensembl chr13:105,580,147...105,584,630
JBrowse link
acridine orange term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bax BCL2-associated X protein increases response to substance ISO BAX protein results in increased susceptibility to Acridine Orange CTD PMID:16177561 NCBI chr 7:45,111,124...45,116,332
Ensembl chr 7:45,111,121...45,116,322
JBrowse link
G Gstp1 glutathione S-transferase, pi 1 multiple interactions ISO [Acridine Orange binds to Platinum Compounds] which results in increased expression of GSTP1 mRNA; [Acridine Orange binds to Platinum] which results in increased expression of GSTP1 mRNA CTD PMID:16814760 NCBI chr19:4,085,411...4,087,912
Ensembl chr19:4,085,407...4,087,985
JBrowse link
G Trp53 transformation related protein 53 multiple interactions ISO Acridine Orange results in increased stability of and results in increased activity of TP53 protein CTD PMID:16177561 NCBI chr11:69,471,174...69,482,699
Ensembl chr11:69,471,185...69,482,699
JBrowse link
ambenonium chloride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase decreases activity ISO Ambenonium Chloride results in decreased activity of ACHE protein CTD PMID:33844597 NCBI chr 5:137,286,516...137,292,728
Ensembl chr 5:137,285,781...137,292,728
JBrowse link
G App amyloid beta precursor protein affects cleavage ISO Ambenonium Chloride affects the cleavage of APP protein CTD PMID:11099780 NCBI chr16:84,751,236...84,972,187
Ensembl chr16:84,746,573...84,970,654
JBrowse link
amprolium term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc19a3 solute carrier family 19, member 3 multiple interactions ISO Amprolium inhibits the reaction [SLC19A3 protein results in increased uptake of Metformin]; Amprolium inhibits the reaction [SLC19A3 protein results in increased uptake of Thiamine] CTD PMID:26528626 NCBI chr 1:82,990,242...83,016,541
Ensembl chr 1:82,990,244...83,016,169
JBrowse link
atomoxetine hydrochloride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp2d22 cytochrome P450, family 2, subfamily d, polypeptide 22 increases hydroxylation
multiple interactions
increases metabolic processing
ISO CYP2D6 protein results in increased hydroxylation of Atomoxetine Hydrochloride
Quinidine inhibits the reaction [CYP2D6 protein results in increased metabolism of Atomoxetine Hydrochloride]
CTD PMID:17470523 PMID:34431675 NCBI chr15:82,254,728...82,264,461
Ensembl chr15:82,254,728...82,264,461
JBrowse link
auramine O term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh1a1 aldehyde dehydrogenase family 1, subfamily A1 increases expression
multiple interactions
ISO Benzophenoneidum results in increased expression of ALDH1A1 protein
ALDH1A1 protein promotes the reaction [Benzophenoneidum results in increased lipidation of and results in increased cleavage of MAP1LC3B protein]
CTD PMID:28722353 NCBI chr19:20,469,947...20,620,827
Ensembl chr19:20,470,079...20,620,829
JBrowse link
G Ano6 anoctamin 6 increases expression ISO Benzophenoneidum results in increased expression of ANO6 protein CTD PMID:28722353 NCBI chr15:95,688,724...95,873,353
Ensembl chr15:95,688,724...95,872,632
JBrowse link
G Araf Araf proto-oncogene, serine/threonine kinase increases expression ISO Benzophenoneidum results in increased expression of ARAF protein CTD PMID:28722353 NCBI chr  X:20,663,946...20,726,760
Ensembl chr  X:20,664,053...20,726,758
JBrowse link
G Atp6ap2 ATPase, H+ transporting, lysosomal accessory protein 2 increases expression ISO Benzophenoneidum results in increased expression of ATP6AP2 protein CTD PMID:28722353 NCBI chr  X:12,453,998...12,483,290
Ensembl chr  X:12,454,040...12,483,288
JBrowse link
G Ccdc22 coiled-coil domain containing 22 increases expression ISO Benzophenoneidum results in increased expression of CCDC22 protein CTD PMID:28722353 NCBI chr  X:7,460,048...7,471,659
Ensembl chr  X:7,460,048...7,471,756
JBrowse link
G Ccdc39 coiled-coil domain containing 39 increases expression ISO Benzophenoneidum results in increased expression of CCDC39 protein CTD PMID:28722353 NCBI chr 3:33,864,906...33,898,473
Ensembl chr 3:33,866,511...33,898,459
JBrowse link
G Cd44 CD44 antigen increases expression ISO Benzophenoneidum results in increased expression of CD44 protein CTD PMID:28722353 NCBI chr 2:102,641,486...102,732,014
Ensembl chr 2:102,641,486...102,732,010
JBrowse link
G Chtf18 CTF18, chromosome transmission fidelity factor 18 increases expression ISO Benzophenoneidum results in increased expression of CHTF18 protein CTD PMID:28722353 NCBI chr17:25,938,004...25,946,409
Ensembl chr17:25,937,900...25,946,393
JBrowse link
G Commd1 COMM domain containing 1 increases expression ISO Benzophenoneidum results in increased expression of COMMD1 protein CTD PMID:28722353 NCBI chr11:22,849,728...22,934,539
Ensembl chr11:22,846,136...22,932,382
JBrowse link
G Cops7b COP9 signalosome subunit 7B increases expression ISO Benzophenoneidum results in increased expression of COPS7B protein CTD PMID:28722353 NCBI chr 1:86,510,363...86,534,550
Ensembl chr 1:86,510,626...86,537,097
JBrowse link
G Cul3 cullin 3 increases expression ISO Benzophenoneidum results in increased expression of CUL3 protein CTD PMID:28722353 NCBI chr 1:80,242,640...80,318,426
Ensembl chr 1:80,242,640...80,318,197
JBrowse link
G Dynlt1b dynein light chain Tctex-type 1B increases expression ISO Benzophenoneidum results in increased expression of DYNLT1 protein CTD PMID:28722353 NCBI chr17:6,697,511...6,703,695
Ensembl chr17:6,697,511...6,703,695
JBrowse link
G Eif4g3 eukaryotic translation initiation factor 4 gamma, 3 increases expression ISO Benzophenoneidum results in increased expression of EIF4G3 protein CTD PMID:28722353 NCBI chr 4:137,719,090...137,934,397
Ensembl chr 4:137,720,333...137,935,819
JBrowse link
G Fastkd2 FAST kinase domains 2 increases expression ISO Benzophenoneidum results in increased expression of FASTKD2 protein CTD PMID:28722353 NCBI chr 1:63,769,758...63,792,544
Ensembl chr 1:63,769,773...63,793,814
JBrowse link
G H2ax H2A.X variant histone increases phosphorylation ISO Benzophenoneidum results in increased phosphorylation of H2AX protein CTD PMID:37527026 NCBI chr 9:44,246,012...44,247,374
Ensembl chr 9:44,245,991...44,247,374
JBrowse link
G Hook3 hook microtubule tethering protein 3 increases expression ISO Benzophenoneidum results in increased expression of HOOK3 protein CTD PMID:28722353 NCBI chr 8:26,511,449...26,609,646
Ensembl chr 8:26,511,449...26,609,252
JBrowse link
G Hsd17b7 hydroxysteroid (17-beta) dehydrogenase 7 increases expression ISO Benzophenoneidum results in increased expression of HSD17B7 protein CTD PMID:28722353 NCBI chr 1:169,777,109...169,796,757
Ensembl chr 1:169,777,104...169,796,810
JBrowse link
G Htt huntingtin increases expression ISO Benzophenoneidum results in increased expression of HTT protein CTD PMID:28722353 NCBI chr 5:34,919,084...35,069,878
Ensembl chr 5:34,919,084...35,069,878
JBrowse link
G Iqgap3 IQ motif containing GTPase activating protein 3 increases expression ISO Benzophenoneidum results in increased expression of IQGAP3 protein CTD PMID:28722353 NCBI chr 3:87,989,309...88,028,355
Ensembl chr 3:87,989,278...88,028,355
JBrowse link
G Kifap3 kinesin-associated protein 3 increases expression ISO Benzophenoneidum results in increased expression of KIFAP3 protein CTD PMID:28722353 NCBI chr 1:163,589,711...163,744,676
Ensembl chr 1:163,607,152...163,744,678
JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta multiple interactions ISO ALDH1A1 protein promotes the reaction [Benzophenoneidum results in increased lipidation of and results in increased cleavage of MAP1LC3B protein]; Benzophenoneidum results in increased lipidation of and results in increased cleavage of MAP1LC3B protein CTD PMID:28722353 NCBI chr 8:122,317,177...122,325,499
Ensembl chr 8:122,317,100...122,325,499
JBrowse link
G Map2k4 mitogen-activated protein kinase kinase 4 increases expression ISO Benzophenoneidum results in increased expression of MAP2K4 protein CTD PMID:28722353 NCBI chr11:65,579,070...65,679,185
Ensembl chr11:65,579,069...65,679,123
JBrowse link
G Mbd3 methyl-CpG binding domain protein 3 increases expression ISO Benzophenoneidum results in increased expression of MBD3 protein CTD PMID:28722353 NCBI chr10:80,228,373...80,235,365
Ensembl chr10:80,228,373...80,235,384
JBrowse link
G Mki67 antigen identified by monoclonal antibody Ki 67 increases expression ISO Benzophenoneidum results in increased expression of MKI67 protein CTD PMID:37527026 NCBI chr 7:135,291,513...135,318,286
Ensembl chr 7:135,291,513...135,318,090
JBrowse link
G Noa1 nitric oxide associated 1 increases expression ISO Benzophenoneidum results in increased expression of NOA1 protein CTD PMID:28722353 NCBI chr 5:77,442,016...77,458,276
Ensembl chr 5:77,442,029...77,457,931
JBrowse link
G Nup62 nucleoporin 62 increases expression ISO Benzophenoneidum results in increased expression of NUP62 protein CTD PMID:28722353 NCBI chr 7:44,465,512...44,481,260
Ensembl chr 7:44,465,512...44,480,236
JBrowse link
G Plcg1 phospholipase C, gamma 1 increases expression ISO Benzophenoneidum results in increased expression of PLCG1 protein CTD PMID:28722353 NCBI chr 2:160,573,230...160,617,680
Ensembl chr 2:160,573,220...160,617,680
JBrowse link
G Ppp4r1 protein phosphatase 4, regulatory subunit 1 increases expression ISO Benzophenoneidum results in increased expression of PPP4R1 protein CTD PMID:28722353 NCBI chr17:66,089,253...66,148,921
Ensembl chr17:66,089,568...66,148,921
JBrowse link
G Prim2 DNA primase, p58 subunit increases expression ISO Benzophenoneidum results in increased expression of PRIM2 protein CTD PMID:28722353 NCBI chr 1:33,492,889...33,708,867
Ensembl chr 1:33,492,891...33,708,876
JBrowse link
G Prom1 prominin 1 increases expression ISO Benzophenoneidum results in increased expression of PROM1 protein CTD PMID:28722353 NCBI chr 5:44,150,963...44,260,850
Ensembl chr 5:44,150,962...44,259,374
JBrowse link
G Prorp protein only RNase P catalytic subunit increases expression ISO Benzophenoneidum results in increased expression of PRORP protein CTD PMID:28722353 NCBI chr12:55,349,422...55,429,276
Ensembl chr12:55,346,362...55,429,318
JBrowse link
G Shmt1 serine hydroxymethyltransferase 1 (soluble) increases expression ISO Benzophenoneidum results in increased expression of SHMT1 protein CTD PMID:28722353 NCBI chr11:60,679,723...60,702,062
Ensembl chr11:60,678,930...60,702,544
JBrowse link
G Srsf11 serine and arginine-rich splicing factor 11 increases expression ISO Benzophenoneidum results in increased expression of SRSF11 protein CTD PMID:28722353 NCBI chr 3:157,716,552...157,742,304
Ensembl chr 3:157,716,110...157,742,276
JBrowse link
G Tbc1d15 TBC1 domain family, member 15 increases expression ISO Benzophenoneidum results in increased expression of TBC1D15 protein CTD PMID:28722353 NCBI chr10:115,031,459...115,087,343
Ensembl chr10:115,033,777...115,087,372
JBrowse link
G Tfam transcription factor A, mitochondrial increases expression ISO Benzophenoneidum results in increased expression of TFAM protein CTD PMID:28722353 NCBI chr10:71,061,298...71,074,157
Ensembl chr10:71,061,294...71,074,110
JBrowse link
G Usp24 ubiquitin specific peptidase 24 increases expression ISO Benzophenoneidum results in increased expression of USP24 protein CTD PMID:28722353 NCBI chr 4:106,173,179...106,303,798
Ensembl chr 4:106,173,417...106,298,519
JBrowse link
G Washc5 WASH complex subunit 5 increases expression ISO Benzophenoneidum results in increased expression of WASHC5 protein CTD PMID:28722353 NCBI chr15:59,203,712...59,246,043
Ensembl chr15:59,203,846...59,246,016
JBrowse link
azure A term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gpt glutamic pyruvic transaminase, soluble increases activity ISO Azure A results in increased activity of GPT protein CTD PMID:33775737 NCBI chr15:76,580,926...76,583,875
Ensembl chr15:76,579,916...76,583,886
JBrowse link
azure B term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G App amyloid beta precursor protein multiple interactions ISO [Azure B affects the cleavage of APP protein] which results in decreased secretion of APP protein modified form; Azure B results in decreased expression of and affects the cleavage of APP protein CTD PMID:30500345 NCBI chr16:84,751,236...84,972,187
Ensembl chr16:84,746,573...84,970,654
JBrowse link
G Bace1 beta-site APP cleaving enzyme 1 decreases activity ISO Azure B results in decreased activity of BACE1 protein CTD PMID:30500345 NCBI chr 9:45,749,878...45,775,694
Ensembl chr 9:45,749,878...45,775,697
JBrowse link
benzalkonium chloride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aacs acetoacetyl-CoA synthetase increases expression EXP Benzalkonium Compounds results in increased expression of AACS mRNA CTD PMID:31199489 NCBI chr 5:125,552,937...125,594,469
Ensembl chr 5:125,552,878...125,594,474
JBrowse link
G Abca1 ATP-binding cassette, sub-family A member 1 decreases expression ISO Benzalkonium Compounds results in decreased expression of ABCA1 mRNA CTD PMID:26919959 NCBI chr 4:53,030,789...53,159,988
Ensembl chr 4:53,030,787...53,159,895
JBrowse link
G Abca12 ATP-binding cassette, sub-family A member 12 increases expression ISO Benzalkonium Compounds results in increased expression of ABCA12 mRNA CTD PMID:25377654 NCBI chr 1:71,282,249...71,454,069
Ensembl chr 1:71,281,435...71,454,069
JBrowse link
G Abca6 ATP-binding cassette, sub-family A member 6 decreases expression ISO Benzalkonium Compounds results in decreased expression of ABCA6 mRNA CTD PMID:20713136 NCBI chr11:110,065,464...110,142,811
Ensembl chr11:110,067,646...110,142,602
JBrowse link
G Acod1 aconitate decarboxylase 1 increases expression EXP Benzalkonium Compounds results in increased expression of ACOD1 mRNA CTD PMID:30171875 NCBI chr14:103,284,448...103,294,009
Ensembl chr14:103,284,413...103,294,009
JBrowse link
G Acp6 acid phosphatase 6, lysophosphatidic increases expression EXP Benzalkonium Compounds results in increased expression of ACP6 mRNA CTD PMID:31199489 NCBI chr 3:97,066,070...97,083,892
Ensembl chr 3:97,066,093...97,084,615
JBrowse link
G Acsl4 acyl-CoA synthetase long-chain family member 4 increases expression EXP Benzalkonium Compounds results in increased expression of ACSL4 mRNA CTD PMID:31199489 NCBI chr  X:141,100,989...141,173,792
Ensembl chr  X:141,100,989...141,173,531
JBrowse link
G Ada adenosine deaminase increases expression EXP Benzalkonium Compounds results in increased expression of ADA mRNA CTD PMID:30171875 NCBI chr 2:163,565,703...163,592,154
Ensembl chr 2:163,568,504...163,592,159
JBrowse link
G Adh1 alcohol dehydrogenase 1 (class I) decreases expression EXP Benzalkonium Compounds results in decreased expression of ADH1 mRNA CTD PMID:31199489 NCBI chr 3:137,983,346...137,996,459
Ensembl chr 3:137,966,752...137,996,459
JBrowse link
G Adora1 adenosine A1 receptor decreases expression EXP Benzalkonium Compounds results in decreased expression of ADORA1 mRNA CTD PMID:30171875 NCBI chr 1:134,126,953...134,163,195
Ensembl chr 1:134,126,963...134,163,169
JBrowse link
G Adra2a adrenergic receptor, alpha 2a multiple interactions EXP [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of ADRA2A mRNA CTD PMID:30171875 NCBI chr19:54,033,690...54,037,413
Ensembl chr19:54,032,582...54,037,413
JBrowse link
G Agtr2 angiotensin II receptor, type 2 multiple interactions EXP [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of AGTR2 mRNA CTD PMID:30171875 NCBI chr  X:21,350,863...21,355,072
Ensembl chr  X:21,350,783...21,355,403
JBrowse link
G Akr1b10 aldo-keto reductase family 1, member B10 increases expression ISO Benzalkonium Compounds results in increased expression of AKR1B10 mRNA CTD PMID:30806763 NCBI chr 6:34,361,182...34,373,884
Ensembl chr 6:34,361,153...34,373,885
JBrowse link
G Alb albumin decreases expression EXP Benzalkonium Compounds results in decreased expression of ALB mRNA CTD PMID:31199489 NCBI chr 5:90,608,729...90,624,461
Ensembl chr 5:90,608,756...90,624,461
JBrowse link
G Amigo2 adhesion molecule with Ig like domain 2 increases expression ISO Benzalkonium Compounds results in increased expression of AMIGO2 mRNA CTD PMID:37149095 NCBI chr15:97,141,955...97,145,168
Ensembl chr15:97,142,006...97,145,168
JBrowse link
G Apoa1 apolipoprotein A-I decreases expression EXP Benzalkonium Compounds results in decreased expression of APOA1 mRNA CTD PMID:31199489 NCBI chr 9:46,139,928...46,141,767
Ensembl chr 9:46,139,878...46,141,764
JBrowse link
G Apoa2 apolipoprotein A-II decreases expression EXP Benzalkonium Compounds results in decreased expression of APOA2 mRNA CTD PMID:31199489 NCBI chr 1:171,049,133...171,053,948
Ensembl chr 1:171,052,623...171,053,948
JBrowse link
G Apoc1 apolipoprotein C-I decreases expression EXP Benzalkonium Compounds results in decreased expression of APOC1 mRNA CTD PMID:31199489 NCBI chr 7:19,423,405...19,426,584
Ensembl chr 7:19,423,406...19,426,585
JBrowse link
G Aqp3 aquaporin 3 increases expression EXP Benzalkonium Compounds results in increased expression of AQP3 mRNA CTD PMID:30171875 NCBI chr 4:41,092,724...41,098,183
Ensembl chr 4:41,092,722...41,098,183
JBrowse link
G Areg amphiregulin increases expression EXP Benzalkonium Compounds results in increased expression of AREG mRNA CTD PMID:30171875 NCBI chr 5:91,287,458...91,296,291
Ensembl chr 5:91,287,458...91,296,291
JBrowse link
G Arg2 arginase type II increases expression EXP Benzalkonium Compounds results in increased expression of ARG2 mRNA CTD PMID:30171875 NCBI chr12:79,177,562...79,203,075
Ensembl chr12:79,177,551...79,203,075
JBrowse link
G Art3 ADP-ribosyltransferase 3 decreases expression EXP Benzalkonium Compounds results in decreased expression of ART3 mRNA CTD PMID:31199489 NCBI chr 5:92,479,659...92,562,487
Ensembl chr 5:92,479,686...92,562,487
JBrowse link
G Atf4 activating transcription factor 4 decreases expression ISO Benzalkonium Compounds results in decreased expression of ATF4 mRNA CTD PMID:28236482 NCBI chr15:80,139,385...80,141,746
Ensembl chr15:80,139,385...80,141,742
JBrowse link
G Atp5f1e ATP synthase F1 subunit epsilon decreases expression EXP Benzalkonium Compounds results in decreased expression of ATP5F1E mRNA CTD PMID:31199489 NCBI chr 2:174,302,868...174,305,894
Ensembl chr 2:174,302,865...174,305,898
JBrowse link
G Atp5mg ATP synthase membrane subunit g decreases expression EXP Benzalkonium Compounds results in decreased expression of ATP5MG mRNA CTD PMID:31199489 NCBI chr 9:44,824,546...44,832,470
Ensembl chr 9:44,823,855...44,832,040
JBrowse link
G B3galt4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4 affects response to substance ISO B3GALT4 SNP affects the susceptibility to Benzalkonium Compounds CTD PMID:27258892 NCBI chr17:34,168,886...34,170,462
Ensembl chr17:34,168,883...34,170,462
JBrowse link
G Bambi BMP and activin membrane-bound inhibitor increases expression ISO Benzalkonium Compounds results in increased expression of BAMBI mRNA CTD PMID:20146380 NCBI chr18:3,507,011...3,516,404
Ensembl chr18:3,507,923...3,516,404
JBrowse link
G Bcl3 B cell leukemia/lymphoma 3 increases expression EXP Benzalkonium Compounds results in increased expression of BCL3 mRNA CTD PMID:30171875 NCBI chr 7:19,542,387...19,556,691
Ensembl chr 7:19,542,387...19,556,695
JBrowse link
G Btc betacellulin, epidermal growth factor family member decreases expression EXP Benzalkonium Compounds results in decreased expression of BTC mRNA CTD PMID:30171875 NCBI chr 5:91,505,120...91,550,853
Ensembl chr 5:91,505,120...91,550,853
JBrowse link
G C1s2 complement component 1, s subcomponent 2 multiple interactions EXP [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of C1S2 mRNA CTD PMID:30171875 NCBI chr 6:124,601,584...124,613,044
Ensembl chr 6:124,601,584...124,613,044
JBrowse link
G C3 complement component 3 multiple interactions EXP [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of C3 mRNA CTD PMID:30171875 NCBI chr17:57,510,967...57,535,136
Ensembl chr17:57,510,970...57,535,136
JBrowse link
G Casp3 caspase 3 increases cleavage
multiple interactions
ISO Benzalkonium Compounds analog results in increased cleavage of CASP3 protein
benzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketone inhibits the reaction [Benzalkonium Compounds analog results in increased cleavage of CASP3 protein]
CTD PMID:31982400 NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724
JBrowse link
G Casp8 caspase 8 decreases expression ISO Benzalkonium Compounds results in decreased expression of CASP8 mRNA CTD PMID:28236482 NCBI chr 1:58,834,553...58,886,663
Ensembl chr 1:58,834,533...58,886,662
JBrowse link
G Ccl11 C-C motif chemokine ligand 11 increases expression EXP Benzalkonium Compounds results in increased expression of CCL11 protein CTD PMID:30517752 NCBI chr11:81,948,658...81,953,781
Ensembl chr11:81,948,649...81,953,781
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 increases expression
increases secretion
EXP
ISO
Benzalkonium Compounds results in increased expression of CCL2 mRNA; Benzalkonium Compounds results in increased expression of CCL2 protein
Benzalkonium Compounds results in increased secretion of CCL2 protein
CTD PMID:30171875 PMID:30517752 PMID:31707104 NCBI chr11:81,926,403...81,928,278
Ensembl chr11:81,926,397...81,928,279
JBrowse link
G Ccl20 C-C motif chemokine ligand 20 increases expression ISO Benzalkonium Compounds results in increased expression of CCL20 mRNA CTD PMID:30806763 NCBI chr 1:83,094,487...83,096,888
Ensembl chr 1:83,094,487...83,096,888
JBrowse link
G Ccl24 C-C motif chemokine ligand 24 decreases expression EXP Benzalkonium Compounds results in decreased expression of CCL24 mRNA CTD PMID:30171875 NCBI chr 5:135,598,789...135,601,977
Ensembl chr 5:135,598,791...135,601,903
JBrowse link
G Ccl3 C-C motif chemokine ligand 3 increases expression
multiple interactions
EXP Benzalkonium Compounds results in increased expression of CCL3 protein
[IL6RA gene mutant form results in increased susceptibility to Benzalkonium Compounds] which results in increased expression of CCL3 protein
CTD PMID:30517752 PMID:31158415 NCBI chr11:83,538,669...83,540,204
Ensembl chr11:83,538,670...83,540,181
JBrowse link
G Ccl4 C-C motif chemokine ligand 4 decreases expression
multiple interactions
increases expression
ISO
EXP
Benzalkonium Compounds results in decreased expression of CCL4 mRNA; Benzalkonium Compounds results in decreased expression of CCL4 protein
[IL6RA gene mutant form results in increased susceptibility to Benzalkonium Compounds] which results in increased expression of CCL4 protein
Benzalkonium Compounds results in increased expression of CCL4 protein
CTD PMID:18353026 PMID:20713136 PMID:30517752 PMID:31158415 NCBI chr11:83,553,410...83,555,509
Ensembl chr11:83,553,410...83,555,509
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 increases expression EXP Benzalkonium Compounds results in increased expression of CCL5 protein CTD PMID:30517752 NCBI chr11:83,416,604...83,421,344
Ensembl chr11:83,416,604...83,421,344
JBrowse link
G Ccl7 C-C motif chemokine ligand 7 increases expression EXP Benzalkonium Compounds results in increased expression of CCL7 mRNA; Benzalkonium Compounds results in increased expression of CCL7 protein CTD PMID:30171875 PMID:30517752 NCBI chr11:81,936,538...81,938,351
Ensembl chr11:81,936,538...81,938,351
JBrowse link
G Ccn2 cellular communication network factor 2 decreases expression ISO Benzalkonium Compounds results in decreased expression of CCN2 mRNA CTD PMID:25377654 NCBI chr10:24,471,340...24,474,581
Ensembl chr10:24,471,340...24,474,581
JBrowse link
G Ccn3 cellular communication network factor 3 increases expression EXP Benzalkonium Compounds results in increased expression of CCN3 mRNA CTD PMID:30171875 NCBI chr15:54,609,306...54,617,158
Ensembl chr15:54,609,098...54,617,435
JBrowse link
G Ccr4 C-C motif chemokine receptor 4 decreases expression EXP Benzalkonium Compounds results in decreased expression of CCR4 mRNA CTD PMID:30171875 NCBI chr 9:114,319,384...114,334,544
Ensembl chr 9:114,319,384...114,333,984
JBrowse link
G Ccr5 C-C motif chemokine receptor 5 increases expression EXP Benzalkonium Compounds results in increased expression of CCR5 mRNA CTD PMID:30171875 NCBI chr 9:123,921,557...123,934,153
Ensembl chr 9:123,921,580...123,947,736
JBrowse link
G Cd177 CD177 antigen multiple interactions EXP [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of CD177 mRNA CTD PMID:30171875 NCBI chr 7:24,443,408...24,459,759
Ensembl chr 7:24,443,408...24,459,736
JBrowse link
G Cd274 CD274 antigen multiple interactions EXP [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of CD274 mRNA CTD PMID:30171875 NCBI chr19:29,339,428...29,365,495
Ensembl chr19:29,344,855...29,365,495
JBrowse link
G Cd300c2 CD300C molecule 2 increases expression EXP Benzalkonium Compounds results in increased expression of CD300C2 mRNA CTD PMID:30171875 NCBI chr11:114,887,595...114,892,706
Ensembl chr11:114,887,547...114,895,058
JBrowse link
G Cdc6 cell division cycle 6 decreases expression
multiple interactions
ISO Benzalkonium Compounds results in decreased expression of CDC6 mRNA; Benzalkonium Compounds results in decreased expression of CDC6 protein
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one promotes the reaction [Benzalkonium Compounds results in decreased expression of CDC6 protein]
CTD PMID:36725023 NCBI chr11:98,798,627...98,814,768
Ensembl chr11:98,798,627...98,814,766
JBrowse link
G Cfap61 cilia and flagella associated protein 61 increases expression EXP Benzalkonium Compounds results in increased expression of CFAP61 mRNA CTD PMID:31199489 NCBI chr 2:145,776,677...146,056,955
Ensembl chr 2:145,776,704...146,056,959
JBrowse link
G Cfd complement factor D decreases expression EXP Benzalkonium Compounds results in decreased expression of CFD mRNA CTD PMID:30171875 NCBI chr10:79,726,687...79,728,489
Ensembl chr10:79,726,687...79,728,489
JBrowse link
G Chi3l1 chitinase 3 like 1 increases expression EXP Benzalkonium Compounds results in increased expression of CHI3L1 mRNA CTD PMID:30171875 NCBI chr 1:134,109,894...134,117,769
Ensembl chr 1:134,109,914...134,117,919
JBrowse link
G Chil3 chitinase-like 3 increases expression EXP Benzalkonium Compounds results in increased expression of CHIL3 mRNA CTD PMID:30171875 NCBI chr 3:106,054,870...106,074,852
Ensembl chr 3:106,054,870...106,074,880
JBrowse link
G Chrnb4 cholinergic receptor, nicotinic, beta polypeptide 4 decreases expression EXP Benzalkonium Compounds results in decreased expression of CHRNB4 mRNA CTD PMID:30171875 NCBI chr 9:54,935,438...54,956,236
Ensembl chr 9:54,935,438...54,956,063
JBrowse link
G Cimap1d CIMAP1 family member D decreases expression EXP Benzalkonium Compounds results in decreased expression of CIMAP1D mRNA CTD PMID:30171875 NCBI chr10:79,475,352...79,491,599
Ensembl chr10:79,475,360...79,481,572
JBrowse link
G Clcf1 cardiotrophin-like cytokine factor 1 increases expression EXP Benzalkonium Compounds results in increased expression of CLCF1 mRNA CTD PMID:30171875 NCBI chr19:4,264,479...4,273,548
Ensembl chr19:4,264,292...4,273,544
JBrowse link
G Cnfn cornifelin increases expression ISO Benzalkonium Compounds results in increased expression of CNFN mRNA; Benzalkonium Compounds results in increased expression of CNFN protein CTD PMID:25377654 NCBI chr 7:25,067,041...25,069,149
Ensembl chr 7:25,067,045...25,069,149
JBrowse link
G Csf1 colony stimulating factor 1 (macrophage) increases expression EXP Benzalkonium Compounds results in increased expression of CSF1 protein CTD PMID:30517752 NCBI chr 3:107,648,364...107,668,048
Ensembl chr 3:107,648,364...107,667,785
JBrowse link
G Csf2 colony stimulating factor 2 (granulocyte-macrophage) increases expression EXP Benzalkonium Compounds results in increased expression of CSF2 protein CTD PMID:30517752 NCBI chr11:54,138,096...54,140,725
Ensembl chr11:54,138,097...54,140,493
JBrowse link
G Csf3 colony stimulating factor 3 (granulocyte) increases expression EXP Benzalkonium Compounds results in increased expression of CSF3 protein CTD PMID:30517752 NCBI chr11:98,591,287...98,594,457
Ensembl chr11:98,592,089...98,594,455
JBrowse link
G Ctps1 cytidine 5'-triphosphate synthase 1 multiple interactions EXP [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of CTPS1 mRNA CTD PMID:30171875 NCBI chr 4:120,397,065...120,427,473
Ensembl chr 4:120,397,065...120,427,473
JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 increases expression
multiple interactions
EXP Benzalkonium Compounds results in increased expression of CXCL10 mRNA; Benzalkonium Compounds results in increased expression of CXCL10 protein
[IL6RA gene mutant form results in increased susceptibility to Benzalkonium Compounds] which results in increased expression of CXCL10 protein
CTD PMID:23445166 PMID:30517752 PMID:31158415 NCBI chr 5:92,494,497...92,496,748
Ensembl chr 5:92,494,497...92,496,748
JBrowse link
G Cxcl15 C-X-C motif chemokine ligand 15 decreases expression
increases expression
increases secretion
decreases secretion
ISO Benzalkonium Compounds results in decreased expression of CXCL8 mRNA; Benzalkonium Compounds results in decreased expression of CXCL8 protein
Benzalkonium Compounds results in increased expression of CXCL8 mRNA
Benzalkonium Compounds results in increased secretion of CXCL8 protein
Benzalkonium Compounds results in decreased secretion of CXCL8 protein
CTD PMID:8006454 PMID:12781210 PMID:16099135 PMID:17763283 PMID:19729060 More... NCBI chr 5:90,942,393...90,950,926
Ensembl chr 5:90,942,393...90,950,926
JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 increases expression
multiple interactions
EXP Benzalkonium Compounds results in increased expression of CXCL2 mRNA; Benzalkonium Compounds results in increased expression of CXCL2 protein
[IL6RA gene mutant form results in increased susceptibility to Benzalkonium Compounds] which results in increased expression of CXCL2 protein
CTD PMID:30171875 PMID:30517752 PMID:31158415 NCBI chr 5:91,051,758...91,053,797
Ensembl chr 5:91,051,730...91,053,797
JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 multiple interactions
increases expression
EXP [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of CXCL3 mRNA
Benzalkonium Compounds results in increased expression of CXCL1 protein; Benzalkonium Compounds results in increased expression of CXCL3 mRNA
CTD PMID:30171875 PMID:30517752 NCBI chr 5:90,933,960...90,935,952
Ensembl chr 5:90,933,962...90,937,459
JBrowse link
G Cxcl5 C-X-C motif chemokine ligand 5 multiple interactions
increases expression
EXP [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of CXCL5 mRNA
Benzalkonium Compounds results in increased expression of CXCL5 mRNA; Benzalkonium Compounds results in increased expression of CXCL5 protein
CTD PMID:30171875 PMID:30517752 NCBI chr 5:90,907,157...90,909,484
Ensembl chr 5:90,907,219...90,909,483
JBrowse link
G Cxcr1 C-X-C motif chemokine receptor 1 increases expression ISO Benzalkonium Compounds results in increased expression of CXCR1 mRNA CTD PMID:30806763 NCBI chr 1:74,228,862...74,233,867
Ensembl chr 1:74,230,944...74,233,790
JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 increases expression ISO Benzalkonium Compounds results in increased expression of CXCR4 mRNA CTD PMID:20713136 NCBI chr 1:128,515,936...128,520,036
Ensembl chr 1:128,515,936...128,520,030
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 decreases expression
increases expression
ISO Benzalkonium Compounds results in decreased expression of CYP1A1 mRNA
Benzalkonium Compounds results in increased expression of CYP1A1 mRNA
CTD PMID:20713136 PMID:30806763 NCBI chr 9:57,595,211...57,611,107
Ensembl chr 9:57,595,211...57,611,107
JBrowse link
G Cyp27a1 cytochrome P450, family 27, subfamily a, polypeptide 1 decreases expression ISO Benzalkonium Compounds results in decreased expression of CYP27A1 mRNA CTD PMID:20713136 NCBI chr 1:74,752,311...74,777,056
Ensembl chr 1:74,752,733...74,777,051
JBrowse link
G Cyp51 cytochrome P450, family 51 increases expression EXP Benzalkonium Compounds results in increased expression of CYP51 mRNA CTD PMID:31199489 NCBI chr 5:4,130,674...4,154,697
Ensembl chr 5:4,131,145...4,154,746
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression ISO Benzalkonium Compounds results in increased expression of DDIT3 mRNA CTD PMID:37149095 NCBI chr10:127,126,662...127,132,160
Ensembl chr10:127,126,643...127,132,157
Ensembl chr10:127,126,643...127,132,157
JBrowse link
G Dhcr24 24-dehydrocholesterol reductase increases expression EXP Benzalkonium Compounds results in increased expression of DHCR24 mRNA CTD PMID:31199489 NCBI chr 4:106,418,279...106,446,310
Ensembl chr 4:106,418,235...106,446,310
JBrowse link
G Dhcr7 7-dehydrocholesterol reductase decreases activity
increases expression
ISO
EXP
Benzalkonium Compounds results in decreased activity of DHCR7 protein
Benzalkonium Compounds results in increased expression of DHCR7 mRNA
CTD PMID:26919959 NCBI chr 7:143,376,827...143,402,147
Ensembl chr 7:143,376,882...143,402,147
JBrowse link
G Dio1 deiodinase, iodothyronine, type I decreases activity ISO Benzalkonium Compounds results in decreased activity of DIO1 protein CTD PMID:30561685 NCBI chr 4:107,148,662...107,164,365
Ensembl chr 4:107,148,662...107,164,366
JBrowse link
G Dio2 deiodinase, iodothyronine, type II decreases activity ISO Benzalkonium Compounds results in decreased activity of DIO2 protein CTD PMID:30561685 NCBI chr12:90,691,326...90,705,812
Ensembl chr12:90,691,326...90,705,812
JBrowse link
G Dio3 deiodinase, iodothyronine type III decreases activity ISO Benzalkonium Compounds results in decreased activity of DIO3 protein CTD PMID:30561685 NCBI chr12:110,245,664...110,247,531
Ensembl chr12:110,245,502...110,247,531
JBrowse link
G Dlk1 delta like non-canonical Notch ligand 1 decreases expression EXP Benzalkonium Compounds results in decreased expression of DLK1 mRNA CTD PMID:31199489 NCBI chr12:109,418,411...109,429,262
Ensembl chr12:109,418,749...109,429,262
JBrowse link
G Dusp1 dual specificity phosphatase 1 increases expression ISO Benzalkonium Compounds results in increased expression of DUSP1 mRNA CTD PMID:30806763 NCBI chr17:26,724,565...26,727,446
Ensembl chr17:26,724,564...26,781,102
JBrowse link
G Dusp10 dual specificity phosphatase 10 increases expression ISO Benzalkonium Compounds results in increased expression of DUSP10 mRNA CTD PMID:37149095 NCBI chr 1:183,766,575...183,807,833
Ensembl chr 1:183,745,499...183,807,833
JBrowse link
G Ebp EBP cholestenol delta-isomerase increases expression ISO Benzalkonium Compounds results in increased expression of EBP mRNA CTD PMID:26919959 NCBI chr  X:8,051,568...8,059,751
Ensembl chr  X:8,051,568...8,059,751
JBrowse link
G Egf epidermal growth factor decreases expression EXP Benzalkonium Compounds results in decreased expression of EGF mRNA CTD PMID:30171875 NCBI chr 3:129,471,223...129,548,971
Ensembl chr 3:129,471,214...129,548,965
JBrowse link
G Egr1 early growth response 1 increases expression ISO Benzalkonium Compounds results in increased expression of EGR1 mRNA CTD PMID:25377654 NCBI chr18:34,994,260...34,998,009
Ensembl chr18:34,992,876...34,998,037
JBrowse link
G Elf3 E74-like factor 3 increases expression EXP Benzalkonium Compounds results in increased expression of ELF3 mRNA CTD PMID:30171875 NCBI chr 1:135,181,312...135,186,210
Ensembl chr 1:135,181,313...135,186,306
JBrowse link
G Elovl1 ELOVL fatty acid elongase 1 increases expression ISO Benzalkonium Compounds results in increased expression of ELOVL1 mRNA CTD PMID:29155129 NCBI chr 4:118,285,321...118,290,150
Ensembl chr 4:118,285,290...118,290,150
JBrowse link
G Elovl6 ELOVL fatty acid elongase 6 increases expression EXP Benzalkonium Compounds results in increased expression of ELOVL6 mRNA CTD PMID:31199489 NCBI chr 3:129,326,035...129,432,144
Ensembl chr 3:129,326,004...129,432,144
JBrowse link
G Endou endonuclease, polyU-specific increases expression EXP Benzalkonium Compounds results in increased expression of ENDOU mRNA CTD PMID:30171875 NCBI chr15:97,608,896...97,629,286
Ensembl chr15:97,608,896...97,629,220
JBrowse link
G Eno1 enolase 1, alpha non-neuron decreases expression EXP Benzalkonium Compounds results in decreased expression of ENO1 mRNA CTD PMID:31199489 NCBI chr 4:150,321,165...150,333,336
Ensembl chr 4:150,321,178...150,333,336
Ensembl chr18:150,321,178...150,333,336
JBrowse link
G Etnk1 ethanolamine kinase 1 increases expression EXP Benzalkonium Compounds results in increased expression of ETNK1 mRNA CTD PMID:31199489 NCBI chr 6:143,112,592...143,154,272
Ensembl chr 6:143,112,947...143,178,033
JBrowse link
G Exo1 exonuclease 1 increases expression EXP Benzalkonium Compounds results in increased expression of EXO1 mRNA CTD PMID:30171875 NCBI chr 1:175,708,334...175,738,962
Ensembl chr 1:175,708,147...175,741,055
JBrowse link
G Ezr ezrin increases expression ISO Benzalkonium Compounds results in increased expression of EZR mRNA; Benzalkonium Compounds results in increased expression of EZR protein CTD PMID:29893927 NCBI chr17:7,005,530...7,050,179
Ensembl chr17:7,005,440...7,050,183
JBrowse link
G Fam83a family with sequence similarity 83, member A increases expression EXP Benzalkonium Compounds results in increased expression of FAM83A mRNA CTD PMID:30171875 NCBI chr15:57,847,983...57,874,102
Ensembl chr15:57,848,815...57,874,405
JBrowse link
G Fgf2 fibroblast growth factor 2 affects response to substance ISO FGF2 SNP affects the susceptibility to Benzalkonium Compounds CTD PMID:27206134 NCBI chr 3:37,402,616...37,464,255
Ensembl chr 3:37,402,495...37,464,257
JBrowse link
G Fgr FGR proto-oncogene, Src family tyrosine kinase increases expression EXP Benzalkonium Compounds results in increased expression of FGR mRNA CTD PMID:30171875 NCBI chr 4:132,701,406...132,729,204
Ensembl chr 4:132,701,406...132,729,221
JBrowse link
G Flg filaggrin increases expression EXP Benzalkonium Compounds results in increased expression of FLG mRNA CTD PMID:30171875 NCBI chr 3:93,180,853...93,200,996
Ensembl chr 3:93,180,830...93,200,993
JBrowse link
G Foxc1 forkhead box C1 multiple interactions EXP [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of FOXC1 mRNA CTD PMID:30171875 NCBI chr13:31,990,629...31,994,618
Ensembl chr13:31,990,616...31,996,459
JBrowse link
G Foxn1 forkhead box N1 multiple interactions EXP [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of FOXN1 mRNA CTD PMID:30171875 NCBI chr11:78,248,403...78,277,597
Ensembl chr11:78,248,403...78,277,384
JBrowse link
G Foxp3 forkhead box P3 multiple interactions EXP [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of FOXP3 mRNA CTD PMID:30171875 NCBI chr  X:7,445,915...7,461,482
Ensembl chr  X:7,439,883...7,461,484
JBrowse link
G Gata3 GATA binding protein 3 multiple interactions EXP [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of GATA3 mRNA CTD PMID:30171875 NCBI chr 2:9,861,889...9,894,845
Ensembl chr 2:9,861,889...9,894,845
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit increases expression ISO Benzalkonium Compounds results in increased expression of GCLC mRNA CTD PMID:30806763 NCBI chr 9:77,661,817...77,701,771
Ensembl chr 9:77,661,817...77,701,767
JBrowse link
G Gclm glutamate-cysteine ligase, modifier subunit increases expression ISO Benzalkonium Compounds results in increased expression of GCLM mRNA CTD PMID:30806763 NCBI chr 3:122,039,206...122,060,864
Ensembl chr 3:122,039,206...122,064,381
JBrowse link
G Gm15283 predicted gene 15283 decreases expression ISO Benzalkonium Compounds results in decreased expression of HIF1A-AS3 CTD PMID:37149095 NCBI chr12:73,981,498...73,999,213
Ensembl chr12:73,889,811...73,996,735
JBrowse link
G Gm22140 predicted gene, 22140 decreases expression ISO Benzalkonium Compounds results in decreased expression of RNU6-454P CTD PMID:37149095 NCBI chr 8:32,676,173...32,676,276
Ensembl chr 8:32,676,157...32,676,276
JBrowse link
G Gm23442 predicted gene, 23442 decreases expression ISO Benzalkonium Compounds results in decreased expression of SNORA38 CTD PMID:37149095 NCBI chr17:35,381,539...35,381,672
Ensembl chr17:35,381,539...35,381,672
JBrowse link
G Gm24411 predicted gene, 24411 decreases expression ISO Benzalkonium Compounds results in decreased expression of SNORA71D mRNA CTD PMID:25377654 NCBI chr 2:158,198,344...158,198,474
Ensembl chr 2:158,198,344...158,198,474
JBrowse link
G Gm25464 predicted gene, 25464 decreases expression ISO Benzalkonium Compounds results in decreased expression of RNU6-643P CTD PMID:37149095 NCBI chr14:122,625,466...122,625,572
Ensembl chr14:122,625,466...122,625,572
JBrowse link
G Gpx2 glutathione peroxidase 2 increases expression EXP Benzalkonium Compounds results in increased expression of GPX2 mRNA CTD PMID:30171875 NCBI chr12:76,839,109...76,842,328
Ensembl chr12:76,839,107...76,842,273
JBrowse link
G Gsdma3 gasdermin A3 multiple interactions EXP [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of GSDMA3 mRNA CTD PMID:30171875 NCBI chr11:98,517,175...98,529,627
Ensembl chr11:98,517,186...98,529,052
JBrowse link
G H2-Oa histocompatibility 2, O region alpha locus affects response to substance ISO HLA-DOA SNP affects the susceptibility to Benzalkonium Compounds CTD PMID:27258892 NCBI chr17:34,311,353...34,314,286
Ensembl chr17:34,311,314...34,314,208
JBrowse link
G H2-Ob histocompatibility 2, O region beta locus affects response to substance ISO HLA-DOB SNP affects the susceptibility to Benzalkonium Compounds CTD PMID:27258892 NCBI chr17:34,457,879...34,464,882
Ensembl chr17:34,457,877...34,473,388
JBrowse link
G H2-Pa histocompatibility 2, P region alpha locus affects response to substance ISO HLA-DPA1 SNP affects the susceptibility to Benzalkonium Compounds CTD PMID:27258892 NCBI chr17:34,303,587...34,304,826
Ensembl chr17:34,303,575...34,304,797
JBrowse link
G Hamp2 hepcidin antimicrobial peptide 2 decreases expression EXP Benzalkonium Compounds results in decreased expression of HAMP2 mRNA CTD PMID:30171875 NCBI chr 7:30,621,797...30,623,606
Ensembl chr 7:30,621,797...30,624,106
JBrowse link
G Hbegf heparin-binding EGF-like growth factor increases expression EXP Benzalkonium Compounds results in increased expression of HBEGF mRNA CTD PMID:30171875 NCBI chr18:36,637,980...36,648,858
Ensembl chr18:36,637,980...36,648,858
JBrowse link
G Hck hemopoietic cell kinase multiple interactions EXP [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of HCK mRNA CTD PMID:30171875 NCBI chr 2:152,950,388...152,993,361
Ensembl chr 2:152,950,388...152,993,361
JBrowse link
G Herpud1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 increases expression ISO Benzalkonium Compounds results in increased expression of HERPUD1 mRNA CTD PMID:37149095 NCBI chr 8:95,113,057...95,121,999
Ensembl chr 8:95,113,066...95,122,005
JBrowse link
G Hgf hepatocyte growth factor multiple interactions EXP [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of HGF mRNA CTD PMID:30171875 NCBI chr 5:16,758,493...16,827,448
Ensembl chr 5:16,758,493...16,825,150
JBrowse link
G Hif1a hypoxia inducible factor 1, alpha subunit increases expression EXP Benzalkonium Compounds results in increased expression of HIF1A mRNA CTD PMID:30171875 NCBI chr12:73,948,186...73,994,304
Ensembl chr12:73,948,149...73,994,304
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-Coenzyme A reductase increases expression ISO
EXP
Benzalkonium Compounds results in increased expression of HMGCR mRNA CTD PMID:26919959 PMID:31199489 NCBI chr13:96,785,470...96,807,444
Ensembl chr13:96,785,475...96,807,444
JBrowse link
G Hmgcs2 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2 increases expression EXP Benzalkonium Compounds results in increased expression of HMGCS2 mRNA CTD PMID:31199489 NCBI chr 3:98,187,747...98,218,054
Ensembl chr 3:98,187,751...98,218,054
JBrowse link
G Hmox1 heme oxygenase 1 increases expression ISO Benzalkonium Compounds results in increased expression of HMOX1 mRNA CTD PMID:37149095 NCBI chr 8:75,820,246...75,827,221
Ensembl chr 8:75,820,249...75,827,217
JBrowse link
G Hoxa7 homeobox A7 decreases expression EXP Benzalkonium Compounds results in decreased expression of HOXA7 mRNA CTD PMID:30171875 NCBI chr 6:52,191,471...52,198,757
Ensembl chr 6:52,191,471...52,198,834
JBrowse link
G Hsd17b7 hydroxysteroid (17-beta) dehydrogenase 7 increases expression EXP Benzalkonium Compounds results in increased expression of HSD17B7 mRNA CTD PMID:31199489 NCBI chr 1:169,777,109...169,796,757
Ensembl chr 1:169,777,104...169,796,810
JBrowse link
G Hspa5 heat shock protein 5 decreases expression ISO Benzalkonium Compounds results in decreased expression of HSPA5 mRNA CTD PMID:28236482 NCBI chr 2:34,662,102...34,666,541
Ensembl chr 2:34,661,982...34,667,559
JBrowse link
G Icam1 intercellular adhesion molecule 1 increases expression ISO Benzalkonium Compounds results in increased expression of ICAM1 mRNA; Benzalkonium Compounds results in increased expression of ICAM1 protein CTD PMID:21742781 PMID:30806763 NCBI chr 9:20,927,236...20,940,110
Ensembl chr 9:20,927,281...20,940,113
JBrowse link
G Id1 inhibitor of DNA binding 1, HLH protein increases expression ISO Benzalkonium Compounds results in increased expression of ID1 mRNA CTD PMID:37149095 NCBI chr 2:152,578,171...152,579,330
Ensembl chr 2:152,578,171...152,579,330
JBrowse link
G Idi1 isopentenyl-diphosphate delta isomerase increases expression EXP Benzalkonium Compounds results in increased expression of IDI1 mRNA CTD PMID:31199489 NCBI chr13:8,935,642...8,942,432
Ensembl chr13:8,935,537...8,942,487
JBrowse link
G Ifna interferon alpha increases expression EXP Benzalkonium Compounds results in increased expression of IFNA protein CTD PMID:30517752
G Ifng interferon gamma increases expression EXP Benzalkonium Compounds results in increased expression of IFNG protein CTD PMID:30517752 NCBI chr10:118,276,951...118,281,799
Ensembl chr10:118,276,951...118,281,797
JBrowse link
G Igha immunoglobulin heavy constant alpha multiple interactions EXP [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of IGHA mRNA CTD PMID:30171875 NCBI chr12:113,219,824...113,223,856
Ensembl chr12:113,218,450...113,223,856
JBrowse link
G Ighg3 Immunoglobulin heavy constant gamma 3 increases expression EXP Benzalkonium Compounds results in increased expression of IGHG3 mRNA CTD PMID:30171875 NCBI chr12:113,321,062...113,324,852
Ensembl chr12:113,319,844...113,324,852
JBrowse link
G Igll1 immunoglobulin lambda-like polypeptide 1 decreases expression EXP Benzalkonium Compounds results in decreased expression of IGHD mRNA CTD PMID:30171875 NCBI chr16:16,678,535...16,681,849
Ensembl chr16:16,678,535...16,681,849
JBrowse link
G Il10 interleukin 10 multiple interactions
increases expression
ISO
EXP
Benzalkonium Compounds results in increased expression of and results in decreased secretion of IL10 protein
[IL6RA gene mutant form results in increased susceptibility to Benzalkonium Compounds] which results in decreased expression of IL10 protein
Benzalkonium Compounds results in increased expression of IL10 protein
CTD PMID:29953848 PMID:30517752 PMID:31158415 NCBI chr 1:130,947,459...130,952,707
Ensembl chr 1:130,947,582...130,952,711
JBrowse link
G Il13ra2 interleukin 13 receptor, alpha 2 increases expression EXP Benzalkonium Compounds results in increased expression of IL13RA2 mRNA CTD PMID:30171875 NCBI chr  X:146,166,474...146,214,982
Ensembl chr  X:146,166,472...146,212,188
JBrowse link
G Il15 interleukin 15 increases expression EXP Benzalkonium Compounds results in increased expression of IL15 protein CTD PMID:30517752 NCBI chr 8:83,058,253...83,129,883
Ensembl chr 8:83,058,261...83,129,851
JBrowse link
G Il17f interleukin 17F increases expression EXP Benzalkonium Compounds results in increased expression of IL17F mRNA CTD PMID:23445166 NCBI chr 1:20,847,370...20,855,498
Ensembl chr 1:20,847,370...20,860,841
JBrowse link
G Il18 interleukin 18 increases expression EXP
ISO
Benzalkonium Compounds results in increased expression of IL18 protein
Benzalkonium Compounds results in increased expression of IL18 mRNA
CTD PMID:30517752 PMID:30806763 NCBI chr 9:50,466,000...50,493,141
Ensembl chr 9:50,466,127...50,493,140
JBrowse link
G Il1a interleukin 1 alpha increases expression
multiple interactions
increases secretion
ISO
EXP
Benzalkonium Compounds results in increased expression of IL1A mRNA; Benzalkonium Compounds results in increased expression of IL1A protein
[IL6RA gene mutant form results in increased susceptibility to Benzalkonium Compounds] which results in increased expression of IL1A protein
Benzalkonium Compounds results in increased secretion of IL1A protein
CTD PMID:8006454 PMID:12781210 PMID:25290854 PMID:30240708 PMID:30517752 More... NCBI chr 2:129,141,530...129,151,892
Ensembl chr 2:129,141,530...129,151,892
JBrowse link
G Il1b interleukin 1 beta increases expression
multiple interactions
ISO
EXP
Benzalkonium Compounds results in increased expression of IL1B protein
[IL6RA gene mutant form results in increased susceptibility to Benzalkonium Compounds] which results in increased expression of IL1B protein
CTD PMID:29953848 PMID:30517752 PMID:31158415 NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059
JBrowse link
G Il1f10 interleukin 1 family, member 10 multiple interactions EXP [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of IL1F10 mRNA CTD PMID:30171875 NCBI chr 2:24,177,095...24,184,236
Ensembl chr 2:24,181,208...24,183,832
JBrowse link
G Il22b interleukin 22B multiple interactions
increases expression
EXP [IL6RA gene mutant form results in increased susceptibility to Benzalkonium Compounds] which results in increased expression of IL22 protein
Benzalkonium Compounds results in increased expression of IL22 protein
CTD PMID:30517752 PMID:31158415 NCBI chr10:118,125,534...118,130,943
Ensembl chr10:118,125,534...118,130,943
JBrowse link
G Il23a interleukin 23, alpha subunit p19 increases expression EXP Benzalkonium Compounds results in increased expression of IL23A mRNA CTD PMID:30171875 NCBI chr10:128,132,009...128,133,953
Ensembl chr10:128,132,008...128,134,621
JBrowse link
G Il24 interleukin 24 increases expression ISO Benzalkonium Compounds results in increased expression of IL24 mRNA CTD PMID:37149095 NCBI chr 1:130,809,801...130,815,153
Ensembl chr 1:130,809,811...130,815,191
JBrowse link
G Il27 interleukin 27 increases expression EXP Benzalkonium Compounds results in increased expression of IL27 protein CTD PMID:30517752 NCBI chr 7:126,188,181...126,194,197
Ensembl chr 7:126,188,182...126,194,113
JBrowse link
G Il3 interleukin 3 increases expression EXP Benzalkonium Compounds results in increased expression of IL3 protein CTD PMID:30517752 NCBI chr11:54,155,911...54,158,105
Ensembl chr11:54,156,129...54,158,103
JBrowse link
G Il31 interleukin 31 increases expression EXP Benzalkonium Compounds results in increased expression of IL31 protein CTD PMID:30517752 NCBI chr 5:123,618,215...123,620,686
Ensembl chr 5:123,618,220...123,627,552
JBrowse link
G Il31ra interleukin 31 receptor A decreases expression EXP Benzalkonium Compounds results in decreased expression of IL31RA mRNA CTD PMID:30171875 NCBI chr13:112,649,439...112,717,266
Ensembl chr13:112,656,432...112,730,894
JBrowse link
G Il34 interleukin 34 decreases expression EXP Benzalkonium Compounds results in decreased expression of IL34 mRNA CTD PMID:30171875 NCBI chr 8:111,467,809...111,532,579
Ensembl chr 8:111,468,461...111,532,556
JBrowse link
G Il36a interleukin 36A increases expression EXP Benzalkonium Compounds results in increased expression of IL36A mRNA CTD PMID:30171875 NCBI chr 2:24,105,429...24,115,713
Ensembl chr 2:24,105,430...24,115,714
JBrowse link
G Il36b interleukin 36B increases expression EXP Benzalkonium Compounds results in increased expression of IL36B mRNA CTD PMID:30171875 NCBI chr 2:24,043,184...24,050,115
Ensembl chr 2:24,043,173...24,050,531
JBrowse link
G Il36g interleukin 36G increases expression EXP Benzalkonium Compounds results in increased expression of IL36G mRNA CTD PMID:30171875 NCBI chr 2:24,076,488...24,083,579
Ensembl chr 2:24,076,488...24,083,580
JBrowse link
G Il4 interleukin 4 increases expression
multiple interactions
EXP Benzalkonium Compounds results in increased expression of IL4 protein
[IL6RA gene mutant form results in increased susceptibility to Benzalkonium Compounds] which results in decreased expression of IL4 protein
CTD PMID:30517752 PMID:31158415 NCBI chr11:53,503,287...53,509,492
Ensembl chr11:53,493,809...53,509,496
JBrowse link
G Il5 interleukin 5 increases expression EXP Benzalkonium Compounds results in increased expression of IL5 protein CTD PMID:30517752 NCBI chr11:53,611,621...53,615,930
Ensembl chr11:53,611,621...53,615,933
JBrowse link
G Il6 interleukin 6 increases secretion
multiple interactions
increases expression
affects response to substance
ISO
EXP
Benzalkonium Compounds results in increased secretion of IL6 protein
[IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of ADRA2A mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of AGTR2 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of C1S2 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of C3 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of CD177 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of CD274 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of CTPS1 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of CXCL3 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of CXCL5 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of FOXC1 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of FOXN1 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of FOXP3 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of GATA3 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of GSDMA3 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of HCK mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of HGF mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of IGHA mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of IL1F10 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of KRT2 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of KRTAP14 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of KRTAP16-3 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of KRTAP19-2 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of KRTAP19-5 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of KRTAP19-9B mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of KRTAP6-1 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of KRTAP6-2 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of LTB mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of MMP25 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of MMP9 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of MRGPRA2B mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of MSX2 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of MYLK3 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of NRG2 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of PDCD1 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of PROKR2 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of PTX3 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of REG1 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of REG3G mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of RYR1 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of SAA3 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of SERPINB13 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of SIGLECE mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of SOX21 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of SRMS mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of ST14 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of TFAP2B mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of TNFRSF13C mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of TNFRSF26 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of TNFSF8 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of TSLP mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of VTCN1 mRNA; [IL6RA gene mutant form results in increased susceptibility to Benzalkonium Compounds] which results in increased expression of IL6 protein
Benzalkonium Compounds results in increased expression of IL6 mRNA; Benzalkonium Compounds results in increased expression of IL6 protein
Benzalkonium Compounds results in increased expression of and results in increased secretion of IL6 protein
CTD PMID:17763283 PMID:28214551 PMID:29953848 PMID:30171875 PMID:30517752 More... NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979
JBrowse link
G Il6ra interleukin 6 receptor, alpha increases response to substance
multiple interactions
EXP IL6RA gene mutant form results in increased susceptibility to Benzalkonium Compounds
[IL6RA gene mutant form results in increased susceptibility to Benzalkonium Compounds] which results in decreased expression of IL10 protein; [IL6RA gene mutant form results in increased susceptibility to Benzalkonium Compounds] which results in decreased expression of IL4 protein; [IL6RA gene mutant form results in increased susceptibility to Benzalkonium Compounds] which results in increased expression of CCL3 protein; [IL6RA gene mutant form results in increased susceptibility to Benzalkonium Compounds] which results in increased expression of CCL4 protein; [IL6RA gene mutant form results in increased susceptibility to Benzalkonium Compounds] which results in increased expression of CXCL10 protein; [IL6RA gene mutant form results in increased susceptibility to Benzalkonium Compounds] which results in increased expression of CXCL2 protein; [IL6RA gene mutant form results in increased susceptibility to Benzalkonium Compounds] which results in increased expression of IL1A protein; [IL6RA gene mutant form results in increased susceptibility to Benzalkonium Compounds] which results in increased expression of IL1B protein; [IL6RA gene mutant form results in increased susceptibility to Benzalkonium Compounds] which results in increased expression of IL22 protein; [IL6RA gene mutant form results in increased susceptibility to Benzalkonium Compounds] which results in increased expression of IL6 protein
CTD PMID:31158415 NCBI chr 3:89,776,631...89,820,503
Ensembl chr 3:89,771,366...89,820,503
JBrowse link
G Il7r interleukin 7 receptor increases expression ISO Benzalkonium Compounds results in increased expression of IL7R mRNA CTD PMID:20713136 NCBI chr15:9,505,880...9,530,270
Ensembl chr15:9,505,874...9,530,262
JBrowse link
G Inhba inhibin beta-A increases expression EXP Benzalkonium Compounds results in increased expression of INHBA mRNA CTD PMID:30171875 NCBI chr13:16,178,841...16,206,194
Ensembl chr13:16,186,436...16,206,206
JBrowse link
G Insig1 insulin induced gene 1 increases expression EXP Benzalkonium Compounds results in increased expression of INSIG1 mRNA CTD PMID:31199489 NCBI chr 5:28,276,410...28,283,660
Ensembl chr 5:28,276,361...28,283,660
JBrowse link
G Isl1 ISL1 transcription factor, LIM/homeodomain decreases expression EXP Benzalkonium Compounds results in decreased expression of ISL1 mRNA CTD PMID:30171875 NCBI chr13:116,434,806...116,446,224
Ensembl chr13:116,434,817...116,446,225
JBrowse link
G Iyd iodotyrosine deiodinase multiple interactions ISO Benzalkonium Compounds inhibits the reaction [IYD protein results in increased metabolism of Monoiodotyrosine] CTD PMID:33352258 NCBI chr10:3,490,274...3,504,880
Ensembl chr10:3,490,240...3,504,877
JBrowse link
G Kcnh2 potassium voltage-gated channel, subfamily H (eag-related), member 2 decreases activity ISO Benzalkonium Compounds results in decreased activity of KCNH2 protein CTD PMID:24052561 NCBI chr 5:24,524,583...24,556,671
Ensembl chr 5:24,524,587...24,556,602
JBrowse link
G Kdm7a lysine (K)-specific demethylase 7A increases expression ISO Benzalkonium Compounds results in increased expression of KDM7A mRNA CTD PMID:37149095 NCBI chr 6:39,113,554...39,183,707
Ensembl chr 6:39,113,557...39,183,723
JBrowse link
G Kdm8 lysine (K)-specific demethylase 8 decreases expression EXP Benzalkonium Compounds results in decreased expression of KDM8 mRNA CTD PMID:31199489 NCBI chr 7:125,043,788...125,062,823
Ensembl chr 7:125,043,848...125,061,441
JBrowse link
G Klf2 Kruppel-like transcription factor 2 (lung) increases expression ISO Benzalkonium Compounds results in increased expression of KLF2 mRNA CTD PMID:37149095 NCBI chr 8:73,072,906...73,075,498
Ensembl chr 8:73,072,877...73,075,500
JBrowse link
G Klk8 kallikrein related-peptidase 8 increases expression EXP Benzalkonium Compounds results in increased expression of KLK8 mRNA CTD PMID:30171875 NCBI chr 7:43,447,001...43,453,250
Ensembl chr 7:43,447,001...43,453,250
JBrowse link
G Krt2 keratin 2 multiple interactions EXP [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of KRT2 mRNA CTD PMID:30171875 NCBI chr15:101,719,124...101,727,391
Ensembl chr15:101,719,124...101,726,604
JBrowse link
G Krt6b keratin 6B increases expression EXP Benzalkonium Compounds results in increased expression of KRT6B mRNA CTD PMID:30171875 NCBI chr15:101,584,458...101,588,728
Ensembl chr15:101,584,458...101,588,722
JBrowse link
G Krtap14 keratin associated protein 14 multiple interactions EXP [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of KRTAP14 mRNA CTD PMID:30171875 NCBI chr16:88,622,179...88,623,033
Ensembl chr16:88,622,178...88,623,033
JBrowse link
G Krtap16-3 keratin associated protein 16-3 multiple interactions EXP [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of KRTAP16-3 mRNA CTD PMID:30171875 NCBI chr16:88,759,192...88,759,761
Ensembl chr16:88,759,161...88,759,761
JBrowse link
G Krtap19-5 keratin associated protein 19-5 multiple interactions EXP [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of KRTAP19-5 mRNA CTD PMID:30171875 NCBI chr16:88,692,856...88,693,337
Ensembl chr16:88,692,856...88,693,345
JBrowse link
G Krtap19-9b keratin associated protein 19-9B multiple interactions EXP [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of KRTAP19-9B mRNA CTD PMID:30171875 NCBI chr16:88,728,692...88,729,152
Ensembl chr16:88,728,692...88,729,153
JBrowse link
G Krtap6-1 keratin associated protein 6-1 multiple interactions EXP [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of KRTAP6-1 mRNA CTD PMID:30171875 NCBI chr16:88,828,587...88,829,180
Ensembl chr16:88,828,587...88,829,180
JBrowse link
G Krtap6-6 keratin associated protein 6-6 multiple interactions EXP [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of KRTAP6-2 mRNA CTD PMID:30171875 NCBI chr16:88,860,297...88,860,890
Ensembl chr16:88,860,300...88,860,890
JBrowse link
G Lce1g late cornified envelope 1G increases expression EXP Benzalkonium Compounds results in increased expression of LCE1G mRNA CTD PMID:30171875 NCBI chr 3:92,657,458...92,659,645
Ensembl chr 3:92,657,455...92,659,645
JBrowse link
G Lce1m late cornified envelope 1M decreases expression EXP Benzalkonium Compounds results in decreased expression of LCE1M mRNA CTD PMID:30171875 NCBI chr 3:92,925,114...92,926,368
Ensembl chr 3:92,925,117...92,926,367
JBrowse link
G Lce3c late cornified envelope 3C increases expression EXP Benzalkonium Compounds results in increased expression of LCE3C mRNA CTD PMID:30171875 NCBI chr 3:92,851,793...92,853,038
Ensembl chr 3:92,851,793...92,853,040
JBrowse link
G Ldha lactate dehydrogenase A decreases expression EXP Benzalkonium Compounds results in decreased expression of LDHA mRNA CTD PMID:31199489 NCBI chr 7:46,491,698...46,505,051
Ensembl chr 7:46,490,899...46,505,051
JBrowse link
G Ldlr low density lipoprotein receptor increases expression EXP Benzalkonium Compounds results in increased expression of LDLR mRNA CTD PMID:31199489 NCBI chr 9:21,634,872...21,661,215
Ensembl chr 9:21,634,779...21,661,215
JBrowse link
G Lif leukemia inhibitory factor increases expression EXP Benzalkonium Compounds results in increased expression of LIF protein CTD PMID:30517752 NCBI chr11:4,207,587...4,222,514
Ensembl chr11:4,207,557...4,222,514
JBrowse link
G Loxl1 lysyl oxidase-like 1 decreases expression EXP Benzalkonium Compounds results in decreased expression of LOXL1 mRNA CTD PMID:31199489 NCBI chr 9:58,195,006...58,220,495
Ensembl chr 9:58,195,021...58,220,469
JBrowse link
G Lst1 leukocyte specific transcript 1 increases expression EXP Benzalkonium Compounds results in increased expression of LST1 mRNA CTD PMID:30171875 NCBI chr17:35,404,071...35,407,416
Ensembl chr17:35,404,071...35,407,415
JBrowse link
G Ltb lymphotoxin B multiple interactions EXP [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of LTB mRNA CTD PMID:30171875 NCBI chr17:35,413,483...35,415,281
Ensembl chr17:35,413,415...35,415,296
JBrowse link
G Mapk14 mitogen-activated protein kinase 14 increases phosphorylation ISO Benzalkonium Compounds results in increased phosphorylation of MAPK14 protein CTD PMID:15737199 NCBI chr17:28,910,316...28,967,379
Ensembl chr17:28,910,303...28,967,380
JBrowse link
G Mesp2 mesoderm posterior 2 decreases expression EXP Benzalkonium Compounds results in decreased expression of MESP2 mRNA CTD PMID:30171875 NCBI chr 7:79,460,475...79,463,179
Ensembl chr 7:79,460,475...79,463,187
JBrowse link
G Mif macrophage migration inhibitory factor (glycosylation-inhibiting factor) increases secretion ISO Benzalkonium Compounds results in increased secretion of MIF protein CTD PMID:31707104 NCBI chr10:75,695,187...75,696,111
Ensembl chr10:75,695,187...75,696,074
JBrowse link
G Mmp10 matrix metallopeptidase 10 increases expression ISO Benzalkonium Compounds results in increased expression of MMP10 mRNA CTD PMID:30806763 NCBI chr 9:7,502,343...7,510,243
Ensembl chr 9:7,502,353...7,510,241
JBrowse link
G Mmp12 matrix metallopeptidase 12 increases expression EXP Benzalkonium Compounds results in increased expression of MMP12 mRNA CTD PMID:30171875 NCBI chr 9:7,344,397...7,360,461
Ensembl chr 9:7,344,381...7,369,499
JBrowse link
G Mmp2 matrix metallopeptidase 2 increases activity ISO Benzalkonium Compounds results in increased activity of MMP2 protein CTD PMID:21058936 NCBI chr 8:93,553,920...93,580,049
Ensembl chr 8:93,553,919...93,580,048
JBrowse link
G Mmp25 matrix metallopeptidase 25 multiple interactions EXP [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of MMP25 mRNA CTD PMID:30171875 NCBI chr17:23,847,289...23,864,006
Ensembl chr17:23,847,285...23,864,251
JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions
increases activity
EXP
ISO
[IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of MMP9 mRNA
Benzalkonium Compounds results in increased activity of MMP9 protein
CTD PMID:21058936 PMID:30171875 NCBI chr 2:164,782,246...164,797,770
Ensembl chr 2:164,782,700...164,797,770
JBrowse link
G Mrgpra2b MAS-related GPR, member A2B multiple interactions EXP [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of MRGPRA2B mRNA CTD PMID:30171875 NCBI chr 7:47,113,555...47,139,330
Ensembl chr 7:47,113,554...47,178,610
JBrowse link
G Msmo1 methylsterol monoxygenase 1 increases expression EXP Benzalkonium Compounds results in increased expression of MSMO1 mRNA CTD PMID:31199489 NCBI chr 8:65,171,157...65,186,822
Ensembl chr 8:65,171,173...65,186,826
JBrowse link
G Msx2 msh homeobox 2 multiple interactions EXP [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of MSX2 mRNA CTD PMID:30171875 NCBI chr13:53,620,917...53,626,816
Ensembl chr13:53,620,920...53,627,110
JBrowse link
G Mt2 metallothionein 2 decreases expression EXP Benzalkonium Compounds results in decreased expression of MT2 mRNA CTD PMID:31199489 NCBI chr 8:94,899,246...94,900,195
Ensembl chr 8:94,899,292...94,900,196
JBrowse link
G Mthfd2 methylenetetrahydrofolate dehydrogenase (NAD+ dependent), methenyltetrahydrofolate cyclohydrolase decreases expression EXP Benzalkonium Compounds results in decreased expression of MTHFD2 mRNA CTD PMID:31199489 NCBI chr 6:83,282,686...83,302,926
Ensembl chr 6:83,282,673...83,302,890
JBrowse link
G Mylk3 myosin light chain kinase 3 multiple interactions EXP [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of MYLK3 mRNA CTD PMID:30171875 NCBI chr 8:86,050,933...86,112,969
Ensembl chr 8:86,050,932...86,112,974
JBrowse link
G Ndufa4 Ndufa4, mitochondrial complex associated decreases expression EXP Benzalkonium Compounds results in decreased expression of NDUFA4 mRNA CTD PMID:31199489 NCBI chr 6:11,900,371...11,907,449
Ensembl chr 6:11,900,291...11,907,496
JBrowse link
G Nr4a2 nuclear receptor subfamily 4, group A, member 2 increases expression ISO Benzalkonium Compounds results in increased expression of NR4A2 mRNA CTD PMID:25377654 NCBI chr 2:56,996,845...57,014,152
Ensembl chr 2:56,996,842...57,014,015
JBrowse link
G Nrg2 neuregulin 2 multiple interactions EXP [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of NRG2 mRNA CTD PMID:30171875 NCBI chr18:36,147,634...36,332,754
Ensembl chr18:36,150,705...36,330,433
JBrowse link
G Ntrk3 neurotrophic tyrosine kinase, receptor, type 3 affects response to substance ISO NTRK3 SNP affects the susceptibility to Benzalkonium Compounds CTD PMID:27206134 NCBI chr 7:77,825,711...78,228,865
Ensembl chr 7:77,825,707...78,387,760
JBrowse link
G Ocln occludin decreases expression EXP Benzalkonium Compounds results in decreased expression of OCLN protein CTD PMID:29514330 NCBI chr13:100,633,012...100,689,226
Ensembl chr13:100,633,015...100,689,226
JBrowse link
G Odc1 ornithine decarboxylase, structural 1 decreases expression EXP Benzalkonium Compounds results in decreased expression of ODC1 mRNA CTD PMID:31199489 NCBI chr12:17,594,906...17,601,503
Ensembl chr12:17,594,795...17,601,506
JBrowse link
G Olr1 oxidized low density lipoprotein (lectin-like) receptor 1 increases expression EXP Benzalkonium Compounds results in increased expression of OLR1 mRNA CTD PMID:30171875 NCBI chr 6:129,456,113...129,484,312
Ensembl chr 6:129,462,207...129,484,128
JBrowse link
G Orm1 orosomucoid 1 decreases expression EXP Benzalkonium Compounds results in decreased expression of ORM1 mRNA CTD PMID:30171875 NCBI chr 4:63,262,793...63,266,400
Ensembl chr 4:63,262,797...63,266,400
JBrowse link
G Parp1 poly (ADP-ribose) polymerase family, member 1 multiple interactions
increases cleavage
ISO benzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketone inhibits the reaction [Benzalkonium Compounds analog results in increased cleavage of PARP1 protein] CTD PMID:31982400 NCBI chr 1:180,396,456...180,428,564
Ensembl chr 1:180,396,489...180,428,819
JBrowse link
G Pbk PDZ binding kinase increases expression EXP Benzalkonium Compounds results in increased expression of PBK mRNA CTD PMID:30171875 NCBI chr14:66,043,337...66,055,271
Ensembl chr14:66,043,286...66,055,271
JBrowse link
G Pcsk9 proprotein convertase subtilisin/kexin type 9 decreases expression EXP Benzalkonium Compounds results in decreased expression of PCSK9 mRNA CTD PMID:31199489 NCBI chr 4:106,299,531...106,321,522
Ensembl chr 4:106,299,526...106,321,526
JBrowse link
G Pdcd1 programmed cell death 1 multiple interactions EXP [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of PDCD1 mRNA CTD PMID:30171875 NCBI chr 1:93,966,027...93,980,278
Ensembl chr 1:93,966,027...93,980,278
JBrowse link
G Pfdn6 prefoldin subunit 6 affects response to substance ISO PFDN6 SNP affects the susceptibility to Benzalkonium Compounds CTD PMID:27258892 NCBI chr17:34,157,883...34,159,317
Ensembl chr17:34,157,795...34,159,317
JBrowse link
G Pglyrp3 peptidoglycan recognition protein 3 increases expression EXP Benzalkonium Compounds results in increased expression of PGLYRP3 mRNA CTD PMID:30171875 NCBI chr 3:91,919,784...91,939,979
Ensembl chr 3:91,921,890...91,938,889
JBrowse link
G Pgp phosphoglycolate phosphatase increases expression EXP Benzalkonium Compounds results in increased expression of PGP mRNA CTD PMID:31199489 NCBI chr17:24,689,400...24,692,084
Ensembl chr17:24,689,366...24,692,084
JBrowse link
G Pla2g5 phospholipase A2, group V decreases expression EXP Benzalkonium Compounds results in decreased expression of PLA2G5 mRNA CTD PMID:30171875 NCBI chr 4:138,526,558...138,590,784
Ensembl chr 4:138,526,555...138,590,793
JBrowse link
G Plcxd3 phosphatidylinositol-specific phospholipase C, X domain containing 3 increases expression EXP Benzalkonium Compounds results in increased expression of PLCXD3 mRNA CTD PMID:31199489 NCBI chr15:4,404,973...4,605,067
Ensembl chr15:4,404,973...4,605,035
JBrowse link
G Plk2 polo like kinase 2 decreases expression ISO Benzalkonium Compounds results in decreased expression of PLK2 mRNA CTD PMID:37149095 NCBI chr13:110,531,578...110,537,378
Ensembl chr13:110,531,580...110,537,378
JBrowse link
G Pnpla2 patatin-like phospholipase domain containing 2 decreases expression EXP Benzalkonium Compounds results in decreased expression of PNPLA2 mRNA CTD PMID:31199489 NCBI chr 7:141,035,101...141,040,656
Ensembl chr 7:141,035,111...141,040,656
JBrowse link
G Polr1d polymerase (RNA) I polypeptide D decreases expression EXP Benzalkonium Compounds results in decreased expression of POLR1D mRNA CTD PMID:31199489 NCBI chr 5:147,013,525...147,048,171
Ensembl chr 5:147,013,860...147,048,407
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha decreases expression EXP Benzalkonium Compounds results in decreased expression of PPARA mRNA CTD PMID:31199489 NCBI chr15:85,619,112...85,691,052
Ensembl chr15:85,619,184...85,687,020
JBrowse link
G Prkaa2 protein kinase, AMP-activated, alpha 2 catalytic subunit increases expression EXP Benzalkonium Compounds results in increased expression of PRKAA2 mRNA CTD PMID:31199489 NCBI chr 4:104,886,846...104,967,095
Ensembl chr 4:104,887,071...104,967,087
JBrowse link
G Prkag2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit increases expression EXP Benzalkonium Compounds results in increased expression of PRKAG2 mRNA CTD PMID:31199489 NCBI chr 5:25,067,733...25,311,576
Ensembl chr 5:25,067,742...25,305,640
JBrowse link
G Prokr2 prokineticin receptor 2 multiple interactions EXP [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of PROKR2 mRNA CTD PMID:30171875 NCBI chr 2:132,211,625...132,227,413
Ensembl chr 2:132,179,653...132,227,367
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 increases expression ISO Benzalkonium Compounds results in increased expression of PTGS2 mRNA CTD PMID:30806763 NCBI chr 1:149,975,851...149,983,978
Ensembl chr 1:149,975,782...149,983,978
JBrowse link
G Ptx3 pentraxin related gene multiple interactions EXP [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of PTX3 mRNA CTD PMID:30171875 NCBI chr 3:66,127,308...66,133,227
Ensembl chr 3:66,127,331...66,133,226
JBrowse link
G Reg1 regenerating islet-derived 1 multiple interactions EXP [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of REG1 mRNA CTD PMID:30171875 NCBI chr 6:78,402,966...78,405,651
Ensembl chr 6:78,399,694...78,405,650
JBrowse link
G Reg3g regenerating islet-derived 3 gamma multiple interactions EXP [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of REG3G mRNA CTD PMID:30171875 NCBI chr 6:78,443,252...78,445,857
Ensembl chr 6:78,443,252...78,445,855
JBrowse link
G Rgl2 ral guanine nucleotide dissociation stimulator-like 2 affects response to substance ISO RGL2 SNP affects the susceptibility to Benzalkonium Compounds CTD PMID:27258892 NCBI chr17:34,148,813...34,156,661
Ensembl chr17:34,148,517...34,156,661
JBrowse link
G Rps18 ribosomal protein S18 affects response to substance ISO RPS18 SNP affects the susceptibility to Benzalkonium Compounds CTD PMID:27258892 NCBI chr17:34,170,972...34,174,639
Ensembl chr17:34,170,973...34,174,975
JBrowse link
G Ryr1 ryanodine receptor 1, skeletal muscle multiple interactions EXP [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of RYR1 mRNA CTD PMID:30171875 NCBI chr 7:28,702,765...28,824,599
Ensembl chr 7:28,702,769...28,824,604
JBrowse link
G Saa3 serum amyloid A 3 multiple interactions EXP [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of SAA3 mRNA CTD PMID:30171875 NCBI chr 7:46,361,422...46,365,100
Ensembl chr 7:46,361,422...46,365,124
JBrowse link
G Scd1 stearoyl-Coenzyme A desaturase 1 decreases expression EXP Benzalkonium Compounds results in decreased expression of SCD1 mRNA CTD PMID:31199489 NCBI chr19:44,382,889...44,396,148
Ensembl chr19:44,382,894...44,396,318
JBrowse link
G Scd2 stearoyl-Coenzyme A desaturase 2 increases expression ISO Benzalkonium Compounds results in increased expression of SCD mRNA CTD PMID:29155129 NCBI chr19:44,282,115...44,295,303
Ensembl chr19:44,282,113...44,295,303
JBrowse link
G Serpinb13 serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 13 multiple interactions EXP [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of SERPINB13 mRNA CTD PMID:30171875 NCBI chr 1:106,908,714...106,928,925
Ensembl chr 1:106,908,714...106,928,925
JBrowse link
G Serpine1 serine (or cysteine) peptidase inhibitor, clade E, member 1 increases expression EXP Benzalkonium Compounds results in increased expression of SERPINE1 mRNA CTD PMID:30171875 NCBI chr 5:137,090,358...137,101,126
Ensembl chr 5:137,090,358...137,101,122
JBrowse link
G Sesn2 sestrin 2 decreases expression EXP Benzalkonium Compounds results in decreased expression of SESN2 mRNA CTD PMID:31199489 NCBI chr 4:132,220,115...132,237,767
Ensembl chr 4:132,219,343...132,237,812
JBrowse link
G Sfn stratifin increases expression EXP Benzalkonium Compounds results in increased expression of SFN mRNA CTD PMID:30171875 NCBI chr 4:133,327,867...133,329,163
Ensembl chr 4:133,327,867...133,329,479
JBrowse link
G Sfrp4 secreted frizzled-related protein 4 decreases expression EXP Benzalkonium Compounds results in decreased expression of SFRP4 mRNA CTD PMID:30171875 NCBI chr13:19,807,345...19,816,995
Ensembl chr13:19,807,274...19,817,164
JBrowse link
G Siglece sialic acid binding Ig-like lectin E multiple interactions EXP [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of SIGLECE mRNA CTD PMID:30171875 NCBI chr 7:43,300,494...43,309,585
Ensembl chr 7:43,300,494...43,309,585
JBrowse link
G Skint7 selection and upkeep of intraepithelial T cells 7 decreases expression EXP Benzalkonium Compounds results in decreased expression of SKINT7 mRNA CTD PMID:30171875 NCBI chr 4:111,830,121...111,845,457
Ensembl chr 4:111,830,120...111,845,420
JBrowse link
G Slc16a1 solute carrier family 16 (monocarboxylic acid transporters), member 1 increases expression EXP Benzalkonium Compounds results in increased expression of SLC16A1 mRNA CTD PMID:31199489 NCBI chr 3:104,545,980...104,565,778
Ensembl chr 3:104,545,984...104,565,778
JBrowse link
G Slc7a11 solute carrier family 7 (cationic amino acid transporter, y+ system), member 11 increases expression ISO Benzalkonium Compounds results in increased expression of SLC7A11 mRNA CTD PMID:30806763 PMID:37149095 NCBI chr 3:50,319,385...50,403,947
Ensembl chr 3:49,846,975...50,398,063
JBrowse link
G Sox21 SRY (sex determining region Y)-box 21 multiple interactions EXP [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of SOX21 mRNA CTD PMID:30171875 NCBI chr14:118,470,645...118,474,442
Ensembl chr14:118,470,644...118,474,442
JBrowse link
G Sprr1a small proline-rich protein 1A increases expression EXP Benzalkonium Compounds results in increased expression of SPRR1A mRNA CTD PMID:30171875 NCBI chr 3:92,391,261...92,393,188
Ensembl chr 3:92,391,259...92,393,202
JBrowse link
G Sprr1b small proline-rich protein 1B increases expression EXP Benzalkonium Compounds results in increased expression of SPRR1B mRNA CTD PMID:30171875 NCBI chr 3:92,344,115...92,346,124
Ensembl chr 3:92,344,116...92,346,096
JBrowse link
G Sprr2a1 small proline-rich protein 2A1 increases expression EXP Benzalkonium Compounds results in increased expression of SPRR2A1 mRNA CTD PMID:30171875 NCBI chr 3:92,123,142...92,129,798
Ensembl chr 3:92,123,106...92,129,218
JBrowse link
G Sprr2a3 small proline-rich protein 2A3 increases expression EXP Benzalkonium Compounds results in increased expression of SPRR2A3 mRNA CTD PMID:30171875 NCBI chr 3:92,192,611...92,196,571
Ensembl chr 3:92,192,724...92,198,712
JBrowse link
G Sprr2b small proline-rich protein 2B increases expression EXP Benzalkonium Compounds results in increased expression of SPRR2B mRNA CTD PMID:30171875 NCBI chr 3:92,224,012...92,225,448
Ensembl chr 3:92,223,927...92,225,392
JBrowse link
G Sprr2f small proline-rich protein 2F increases expression EXP Benzalkonium Compounds results in increased expression of SPRR2F mRNA CTD PMID:30171875 NCBI chr 3:92,272,494...92,273,754
Ensembl chr 3:92,272,494...92,273,749
JBrowse link
G Sprr2h small proline-rich protein 2H increases expression EXP Benzalkonium Compounds results in increased expression of SPRR2H mRNA CTD PMID:30171875 NCBI chr 3:92,292,992...92,294,631
Ensembl chr 3:92,292,992...92,294,631
JBrowse link
G Sprr2i small proline-rich protein 2I increases expression EXP Benzalkonium Compounds results in increased expression of SPRR2I mRNA CTD PMID:30171875 NCBI chr 3:92,315,298...92,316,577
Ensembl chr 3:92,315,298...92,316,578
JBrowse link
G Sqle squalene epoxidase increases expression EXP Benzalkonium Compounds results in increased expression of SQLE mRNA CTD PMID:31199489 NCBI chr15:59,186,941...59,203,042
Ensembl chr15:59,186,926...59,203,041
JBrowse link
G Srebf2 sterol regulatory element binding factor 2 increases expression ISO Benzalkonium Compounds results in increased expression of SREBF2 mRNA CTD PMID:26919959 NCBI chr15:82,031,455...82,089,580
Ensembl chr15:82,031,382...82,089,580
JBrowse link
G Srms src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites multiple interactions EXP [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of SRMS mRNA CTD PMID:30171875 NCBI chr 2:180,847,356...180,854,964
Ensembl chr 2:180,847,355...180,854,978
JBrowse link
G St14 suppression of tumorigenicity 14 (colon carcinoma) multiple interactions EXP [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of ST14 mRNA CTD PMID:30171875 NCBI chr 9:30,999,886...31,043,138
Ensembl chr 9:31,000,698...31,043,149
JBrowse link
G Tapbp TAP binding protein affects response to substance ISO TAPBP SNP affects the susceptibility to Benzalkonium Compounds CTD PMID:27258892 NCBI chr17:34,138,452...34,148,264
Ensembl chr17:34,134,873...34,148,266
JBrowse link
G Tfap2b transcription factor AP-2 beta multiple interactions EXP [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of TFAP2B mRNA CTD PMID:30171875 NCBI chr 1:19,279,132...19,309,071
Ensembl chr 1:19,279,138...19,308,800
JBrowse link
G Tgfb1 transforming growth factor, beta 1 increases expression EXP Benzalkonium Compounds results in increased expression of TGFB1 protein CTD PMID:30517752 NCBI chr 7:25,386,406...25,404,503
Ensembl chr 7:25,386,427...25,404,502
JBrowse link
G Tgm3 transglutaminase 3, E polypeptide increases expression EXP Benzalkonium Compounds results in increased expression of TGM3 mRNA CTD PMID:30171875 NCBI chr 2:129,829,700...129,890,814
Ensembl chr 2:129,854,269...129,892,319
JBrowse link
G Tgm7 transglutaminase 7 decreases expression EXP Benzalkonium Compounds results in decreased expression of TGM7 mRNA CTD PMID:30171875 NCBI chr 2:120,923,979...120,946,877
Ensembl chr 2:120,924,046...120,946,877
JBrowse link
G Thbs1 thrombospondin 1 increases expression EXP Benzalkonium Compounds results in increased expression of THBS1 mRNA CTD PMID:30171875 NCBI chr 2:117,942,357...117,957,614
Ensembl chr 2:117,942,357...117,957,614
JBrowse link
G Tlr1 toll-like receptor 1 increases expression EXP Benzalkonium Compounds results in increased expression of TLR1 mRNA CTD PMID:30171875 NCBI chr 5:65,082,023...65,090,945
Ensembl chr 5:65,082,022...65,090,906
JBrowse link
G Tlr4 toll-like receptor 4 increases activity EXP Benzalkonium Compounds results in increased activity of TLR4 protein CTD PMID:29514330 NCBI chr 4:66,745,788...66,765,338
Ensembl chr 4:66,745,821...66,848,521
JBrowse link
G Tmprss11b transmembrane protease, serine 11B increases expression EXP Benzalkonium Compounds results in increased expression of TMPRSS11B mRNA CTD PMID:30171875 NCBI chr 5:86,806,326...86,824,221
Ensembl chr 5:86,805,490...86,824,221
JBrowse link
G Tnf tumor necrosis factor decreases secretion
increases expression
ISO
EXP
Benzalkonium Compounds results in decreased secretion of TNF protein
Benzalkonium Compounds results in increased expression of TNF mRNA; Benzalkonium Compounds results in increased expression of TNF protein
CTD PMID:29953848 PMID:30171875 PMID:30517752 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983
JBrowse link
G Tnfaip6 tumor necrosis factor alpha induced protein 6 increases expression EXP Benzalkonium Compounds results in increased expression of TNFAIP6 mRNA CTD PMID:30171875 NCBI chr 2:51,928,125...51,946,693
Ensembl chr 2:51,928,021...51,946,698
JBrowse link
G Tnfrsf13c tumor necrosis factor receptor superfamily, member 13c multiple interactions EXP [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of TNFRSF13C mRNA CTD PMID:30171875 NCBI chr15:82,105,943...82,108,581
Ensembl chr15:82,105,944...82,108,570
JBrowse link
G Tnfrsf26 tumor necrosis factor receptor superfamily, member 26 multiple interactions EXP [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of TNFRSF26 mRNA CTD PMID:30171875 NCBI chr 7:143,161,422...143,181,690
Ensembl chr 7:143,161,396...143,182,459
JBrowse link
G Tnfrsf9 tumor necrosis factor receptor superfamily, member 9 increases expression EXP Benzalkonium Compounds results in increased expression of TNFRSF9 mRNA CTD PMID:30171875 NCBI chr 4:151,004,612...151,030,561
Ensembl chr 4:150,999,019...151,030,559
JBrowse link
G Tnfsf8 tumor necrosis factor (ligand) superfamily, member 8 multiple interactions EXP [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of TNFSF8 mRNA CTD PMID:30171875 NCBI chr 4:63,749,439...63,779,745
Ensembl chr 4:63,749,545...63,779,584
JBrowse link
G Tpi1 triosephosphate isomerase 1 decreases expression EXP Benzalkonium Compounds results in decreased expression of TPI1 mRNA CTD PMID:31199489 NCBI chr 6:124,787,549...124,791,121
Ensembl chr 6:124,787,549...124,791,259
JBrowse link
G Trdc T cell receptor delta, constant region decreases expression EXP Benzalkonium Compounds results in decreased expression of TRDC mRNA CTD PMID:30171875 NCBI chr14:54,380,308...54,383,565
Ensembl chr14:54,380,308...54,386,325
JBrowse link
G Trdv4 T cell receptor delta variable 4 decreases expression EXP Benzalkonium Compounds results in decreased expression of TRDV4 mRNA CTD PMID:30171875 NCBI chr14:54,312,461...54,312,972
Ensembl chr14:54,312,362...54,312,972
JBrowse link
G Trem2 triggering receptor expressed on myeloid cells 2 increases expression EXP Benzalkonium Compounds results in increased expression of TREM2 mRNA CTD PMID:30171875 NCBI chr17:48,653,429...48,659,304
Ensembl chr17:48,653,429...48,661,175
JBrowse link
G Trib3 tribbles pseudokinase 3 increases expression ISO Benzalkonium Compounds results in increased expression of TRIB3 mRNA CTD PMID:37149095 NCBI chr 2:152,179,345...152,185,980
Ensembl chr 2:152,179,342...152,185,952
JBrowse link
G Trp53 transformation related protein 53 decreases expression ISO Benzalkonium Compounds results in decreased expression of TP53 mRNA CTD PMID:28236482 NCBI chr11:69,471,174...69,482,699
Ensembl chr11:69,471,185...69,482,699
JBrowse link
G Tslp thymic stromal lymphopoietin multiple interactions EXP [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of TSLP mRNA CTD PMID:30171875 NCBI chr18:32,948,436...32,952,852
Ensembl chr18:32,948,436...32,952,850
JBrowse link
G Ulbp1 UL16 binding protein 1 increases expression ISO Benzalkonium Compounds results in increased expression of ULBP1 mRNA CTD PMID:37149095 NCBI chr10:7,394,873...7,423,643
Ensembl chr10:7,390,362...7,423,638
JBrowse link
G Upk3b uroplakin 3B decreases expression EXP Benzalkonium Compounds results in decreased expression of UPK3B mRNA CTD PMID:30171875 NCBI chr 5:136,067,350...136,073,847
Ensembl chr 5:136,067,350...136,075,341
JBrowse link
G Uqcrq ubiquinol-cytochrome c reductase, complex III subunit VII decreases expression EXP Benzalkonium Compounds results in decreased expression of UQCRQ mRNA CTD PMID:31199489 NCBI chr11:53,318,749...53,321,658
Ensembl chr11:53,318,749...53,321,658
JBrowse link
G Vegfd vascular endothelial growth factor D increases expression ISO Benzalkonium Compounds results in increased expression of VEGFD mRNA CTD PMID:20146380 NCBI chr  X:163,156,282...163,185,643
Ensembl chr  X:163,156,374...163,185,646
JBrowse link
G Vtcn1 V-set domain containing T cell activation inhibitor 1 multiple interactions EXP [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of VTCN1 mRNA CTD PMID:30171875 NCBI chr 3:100,732,775...100,805,555
Ensembl chr 3:100,732,775...100,804,238
JBrowse link
G Wdr46 WD repeat domain 46 affects response to substance ISO WDR46 SNP affects the susceptibility to Benzalkonium Compounds CTD PMID:27258892 NCBI chr17:34,159,608...34,168,669
Ensembl chr17:34,159,634...34,168,671
JBrowse link
G Xbp1 X-box binding protein 1 decreases expression ISO Benzalkonium Compounds results in decreased expression of XBP1 mRNA alternative form CTD PMID:28236482 NCBI chr11:5,470,641...5,475,993
Ensembl chr11:5,470,659...5,475,893
JBrowse link
G Xcl1 chemokine (C motif) ligand 1 decreases expression EXP Benzalkonium Compounds results in decreased expression of XCL1 mRNA CTD PMID:30171875 NCBI chr 1:164,759,216...164,763,094
Ensembl chr 1:164,759,213...164,763,096
JBrowse link
butylscopolamine bromide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc22a2 solute carrier family 22 (organic cation transporter), member 2 multiple interactions ISO Butylscopolammonium Bromide inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr17:12,803,076...12,847,376
Ensembl chr17:12,803,019...12,847,375
JBrowse link
chlormequat chloride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcd1 ATP-binding cassette, sub-family D member 1 increases expression ISO Chlormequat results in increased expression of ABCD1 protein CTD PMID:34958886 NCBI chr  X:72,760,203...72,782,140
Ensembl chr  X:72,760,203...72,782,140
JBrowse link
G Adarb1 adenosine deaminase, RNA-specific, B1 decreases expression ISO Chlormequat results in decreased expression of ADARB1 protein CTD PMID:34958886 NCBI chr10:77,126,561...77,254,125
Ensembl chr10:77,126,560...77,254,104
JBrowse link
G Agtrap angiotensin II, type I receptor-associated protein increases expression ISO Chlormequat results in increased expression of AGTRAP protein CTD PMID:34958886 NCBI chr 4:148,161,518...148,172,521
Ensembl chr 4:148,161,518...148,172,488
JBrowse link
G Ahr aryl-hydrocarbon receptor multiple interactions ISO Chlormequat promotes the reaction [Tetrachlorodibenzodioxin results in increased activity of AHR protein] CTD PMID:25684042 NCBI chr12:35,547,978...35,584,988
Ensembl chr12:35,547,973...35,585,037
JBrowse link
G Alg12 ALG12 alpha-1,6-mannosyltransferase decreases expression ISO Chlormequat results in decreased expression of ALG12 protein CTD PMID:34958886 NCBI chr15:88,689,448...88,703,498
Ensembl chr15:88,689,447...88,703,521
JBrowse link
G Alg14 asparagine-linked glycosylation 14 decreases expression ISO Chlormequat results in decreased expression of ALG14 protein CTD PMID:34958886 NCBI chr 3:121,085,361...121,156,745
Ensembl chr 3:121,085,422...121,156,743
JBrowse link
G Apol9a apolipoprotein L 9a increases expression ISO Chlormequat results in increased expression of APOL9A protein CTD PMID:34958886 NCBI chr15:77,287,989...77,295,280
Ensembl chr15:77,287,989...77,295,335
JBrowse link
G Arhgap20 Rho GTPase activating protein 20 increases expression ISO Chlormequat results in increased expression of ARHGAP20 protein CTD PMID:34958886 NCBI chr 9:51,676,651...51,765,158
Ensembl chr 9:51,676,637...51,765,156
JBrowse link
G Atl1 atlastin GTPase 1 increases expression ISO Chlormequat results in increased expression of ATL1 protein CTD PMID:34958886 NCBI chr12:69,939,879...70,010,859
Ensembl chr12:69,939,388...70,013,191
JBrowse link
G Atp10b ATPase, class V, type 10B increases expression ISO Chlormequat results in increased expression of ATP10B protein CTD PMID:34958886 NCBI chr11:42,902,991...43,153,112
Ensembl chr11:43,040,704...43,153,112
JBrowse link
G B9d2 B9 protein domain 2 increases expression ISO Chlormequat results in increased expression of B9D2 protein CTD PMID:34958886 NCBI chr 7:25,380,205...25,385,987
Ensembl chr 7:25,380,205...25,385,983
JBrowse link
G Bet1l Bet1 golgi vesicular membrane trafficking protein like increases expression ISO Chlormequat results in increased expression of BET1L protein CTD PMID:34958886 NCBI chr 7:140,433,297...140,437,306
Ensembl chr 7:140,433,307...140,437,490
JBrowse link
G Bglap bone gamma carboxyglutamate protein decreases expression ISO Chlormequat results in decreased expression of BGLAP protein CTD PMID:28214531 NCBI chr 3:88,290,802...88,291,773
Ensembl chr 3:88,290,808...88,291,771
JBrowse link
G C1qc complement component 1, q subcomponent, C chain increases expression ISO Chlormequat results in increased expression of C1QC protein CTD PMID:34958886 NCBI chr 4:136,617,115...136,620,225
Ensembl chr 4:136,617,115...136,620,376
JBrowse link
G Caap1 caspase activity and apoptosis inhibitor 1 decreases expression ISO Chlormequat results in decreased expression of CAAP1 protein CTD PMID:34958886 NCBI chr 4:94,388,318...94,445,033
Ensembl chr 4:94,388,318...94,445,033
JBrowse link
G Cbx1 chromobox 1 increases expression ISO Chlormequat results in increased expression of CBX1 protein CTD PMID:34958886 NCBI chr11:96,679,506...96,699,808
Ensembl chr11:96,679,953...96,699,466
JBrowse link
G Ccdc32 coiled-coil domain containing 32 increases expression ISO Chlormequat results in increased expression of CCDC32 protein CTD PMID:34958886 NCBI chr 2:118,848,260...118,859,887
Ensembl chr 2:118,848,260...118,859,874
JBrowse link
G Ccnyl1 cyclin Y-like 1 increases expression ISO Chlormequat results in increased expression of CCNYL1 protein CTD PMID:34958886 NCBI chr 1:64,729,963...64,764,805
Ensembl chr 1:64,729,614...64,764,803
JBrowse link
G Ccs copper chaperone for superoxide dismutase increases expression ISO Chlormequat results in increased expression of CCS protein CTD PMID:34958886 NCBI chr19:4,875,394...4,889,326
Ensembl chr19:4,875,394...4,889,360
JBrowse link
G Cd151 CD151 antigen decreases expression ISO Chlormequat results in decreased expression of CD151 protein CTD PMID:34958886 NCBI chr 7:141,047,275...141,051,394
Ensembl chr 7:141,047,305...141,051,386
JBrowse link
G Cd55 CD55 molecule, decay accelerating factor for complement increases expression ISO Chlormequat results in increased expression of CD55 protein CTD PMID:34958886 NCBI chr 1:130,357,526...130,390,513
Ensembl chr 1:130,366,764...130,390,481
JBrowse link
G Cfap298 cilia and flagella associate protien 298 increases expression ISO Chlormequat results in increased expression of CFAP298 protein CTD PMID:34958886 NCBI chr16:90,721,178...90,731,737
Ensembl chr16:90,722,697...90,732,002
JBrowse link
G Chmp7 charged multivesicular body protein 7 increases expression ISO Chlormequat results in increased expression of CHMP7 protein CTD PMID:34958886 NCBI chr14:69,954,428...69,970,019
Ensembl chr14:69,954,449...69,969,990
JBrowse link
G Coprs coordinator of PRMT5, differentiation stimulator increases expression ISO Chlormequat results in increased expression of COPRS protein CTD PMID:34958886 NCBI chr 8:13,934,787...13,940,501
Ensembl chr 8:13,934,794...13,940,281
JBrowse link
G Coq4 coenzyme Q4 increases expression ISO Chlormequat results in increased expression of COQ4 protein CTD PMID:34958886 NCBI chr 2:29,677,505...29,687,947
Ensembl chr 2:29,677,505...29,687,947
JBrowse link
G Creb1 cAMP responsive element binding protein 1 increases phosphorylation ISO Chlormequat results in increased phosphorylation of CREB1 protein CTD PMID:38552810 NCBI chr 1:64,571,963...64,643,707
Ensembl chr 1:64,571,804...64,643,707
JBrowse link
G Csnk1a1 casein kinase 1, alpha 1 increases expression ISO Chlormequat results in increased expression of CSNK1A1 protein CTD PMID:34958886 NCBI chr18:61,687,307...61,723,391
Ensembl chr18:61,688,345...61,723,132
JBrowse link
G Ctss cathepsin S decreases expression ISO Chlormequat results in decreased expression of CTSS protein CTD PMID:34958886 NCBI chr 3:95,434,097...95,463,716
Ensembl chr 3:95,434,097...95,463,714
JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 decreases expression ISO Chlormequat results in decreased expression of CYP11A1 protein CTD PMID:29447956 NCBI chr 9:57,905,307...57,934,314
Ensembl chr 9:57,913,694...57,934,306
JBrowse link
G Cyp7a1 cytochrome P450, family 7, subfamily a, polypeptide 1 increases expression ISO Chlormequat results in increased expression of CYP7A1 protein CTD PMID:32194361 NCBI chr 4:6,265,612...6,275,632
Ensembl chr 4:6,265,612...6,275,633
JBrowse link
G Dap death-associated protein decreases expression ISO Chlormequat results in decreased expression of DAP protein CTD PMID:34958886 NCBI chr15:31,224,531...31,274,484
Ensembl chr15:31,224,460...31,274,487
JBrowse link
G Dcaf13 DDB1 and CUL4 associated factor 13 increases expression ISO Chlormequat results in increased expression of DCAF13 protein CTD PMID:34958886 NCBI chr15:38,976,300...39,010,251
Ensembl chr15:38,976,260...39,010,251
JBrowse link
G Dctn6 dynactin 6 increases expression ISO Chlormequat results in increased expression of DCTN6 protein CTD PMID:34958886 NCBI chr 8:34,557,574...34,575,866
Ensembl chr 8:34,557,574...34,575,950
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 multiple interactions
increases expression
ISO 4-phenylbutyric acid inhibits the reaction [Chlormequat results in increased expression of DDIT3 protein] CTD PMID:34958886 NCBI chr10:127,126,662...127,132,160
Ensembl chr10:127,126,643...127,132,157
Ensembl chr10:127,126,643...127,132,157
JBrowse link
G Degs1 delta 4-desaturase, sphingolipid 1 increases expression ISO Chlormequat results in increased expression of DEGS1 protein CTD PMID:34958886 NCBI chr 1:182,103,529...182,110,366
Ensembl chr 1:182,103,337...182,110,369
JBrowse link
G Dnajc14 DnaJ heat shock protein family (Hsp40) member C14 increases expression ISO Chlormequat results in increased expression of DNAJC14 protein CTD PMID:34958886 NCBI chr10:128,641,423...128,655,317
Ensembl chr10:128,639,931...128,655,315
JBrowse link
G Dnmbp dynamin binding protein increases expression ISO Chlormequat results in increased expression of DNMBP protein CTD PMID:34958886 NCBI chr19:43,835,259...43,930,930
Ensembl chr19:43,835,260...43,928,630
JBrowse link
G Dynlt3 dynein light chain Tctex-type 3 increases expression ISO Chlormequat results in increased expression of DYNLT3 protein CTD PMID:34958886 NCBI chr  X:9,520,509...9,529,222
Ensembl chr  X:9,520,506...9,529,242
JBrowse link
G Ears2 glutamyl-tRNA synthetase 2, mitochondrial increases expression ISO Chlormequat results in increased expression of EARS2 protein CTD PMID:34958886 NCBI chr 7:121,633,385...121,666,436
Ensembl chr 7:121,636,436...121,666,486
JBrowse link
G Eef1a2 eukaryotic translation elongation factor 1 alpha 2 decreases expression ISO Chlormequat results in decreased expression of EEF1A2 protein CTD PMID:34958886 NCBI chr 2:180,783,551...180,798,808
Ensembl chr 2:180,789,446...180,798,807
JBrowse link
G Elovl1 ELOVL fatty acid elongase 1 increases expression ISO Chlormequat results in increased expression of ELOVL1 protein CTD PMID:34958886 NCBI chr 4:118,285,321...118,290,150
Ensembl chr 4:118,285,290...118,290,150
JBrowse link
G Elovl5 ELOVL fatty acid elongase 5 increases expression ISO Chlormequat results in increased expression of ELOVL5 protein CTD PMID:34958886 NCBI chr 9:77,824,647...77,891,801
Ensembl chr 9:77,824,646...77,891,801
JBrowse link
G Eno3 enolase 3, beta muscle decreases expression ISO Chlormequat results in decreased expression of ENO3 protein CTD PMID:34958886 NCBI chr11:70,543,973...70,553,339
Ensembl chr11:70,548,028...70,553,339
JBrowse link
G Evc EvC ciliary complex subunit 1 increases expression ISO Chlormequat results in increased expression of EVC protein CTD PMID:34958886 NCBI chr 5:37,446,314...37,495,489
Ensembl chr 5:37,446,442...37,494,238
JBrowse link
G Fabp4 fatty acid binding protein 4, adipocyte decreases expression ISO Chlormequat results in decreased expression of FABP4 protein CTD PMID:34958886 NCBI chr 3:10,269,406...10,273,653
Ensembl chr 3:10,269,148...10,273,636
JBrowse link
G Fancd2 Fanconi anemia, complementation group D2 decreases expression ISO Chlormequat results in decreased expression of FANCD2 protein CTD PMID:34958886 NCBI chr 6:113,508,622...113,573,981
Ensembl chr 6:113,508,643...113,573,978
JBrowse link
G Fbln1 fibulin 1 increases expression ISO Chlormequat results in increased expression of FBLN1 protein CTD PMID:34958886 NCBI chr15:85,090,150...85,170,495
Ensembl chr15:85,090,150...85,170,736
JBrowse link
G Fos FBJ osteosarcoma oncogene decreases expression ISO Chlormequat results in decreased expression of FOS protein CTD PMID:34958886 NCBI chr12:85,520,664...85,524,048
Ensembl chr12:85,520,664...85,524,047
JBrowse link
G Foxk2 forkhead box K2 decreases expression ISO Chlormequat results in decreased expression of FOXK2 protein CTD PMID:34958886 NCBI chr11:121,150,805...121,200,726
Ensembl chr11:121,150,816...121,200,722
JBrowse link
G Gabarap gamma-aminobutyric acid receptor associated protein increases expression ISO Chlormequat results in increased expression of GABARAP protein CTD PMID:34958886 NCBI chr11:69,882,196...69,885,775
Ensembl chr11:69,881,969...69,885,777
JBrowse link
G Gh growth hormone increases expression ISO Chlormequat results in increased expression of GH1 protein CTD PMID:31704167 PMID:32622971 PMID:38552810 NCBI chr11:106,191,087...106,194,529
Ensembl chr11:106,191,097...106,192,691
JBrowse link
G Ghr growth hormone receptor decreases expression ISO Chlormequat results in decreased expression of GHR mRNA CTD PMID:28214531 NCBI chr15:3,347,237...3,612,834
Ensembl chr15:3,347,242...3,612,974
JBrowse link
G Ghrh growth hormone releasing hormone increases expression ISO Chlormequat results in increased expression of GHRH protein CTD PMID:32622971 PMID:38552810 NCBI chr 2:157,171,416...157,190,645
Ensembl chr 2:157,171,417...157,189,426
JBrowse link
G Gnai1 G protein subunit alpha i1 increases expression ISO Chlormequat results in increased expression of GNAI1 protein CTD PMID:34958886 NCBI chr 5:18,470,133...18,565,411
Ensembl chr 5:18,470,133...18,565,353
JBrowse link
G Gng5 G protein subunit gamma 5 decreases expression ISO Chlormequat results in decreased expression of GNG5 protein CTD PMID:34958886 NCBI chr 3:146,205,591...146,211,298
Ensembl chr 3:146,205,562...146,211,327
JBrowse link
G Gnrh1 gonadotropin releasing hormone 1 increases expression ISO Chlormequat results in increased expression of GNRH1 protein CTD PMID:29447956 NCBI chr14:67,982,717...67,986,889
Ensembl chr14:67,982,630...67,986,888
JBrowse link
G Gsta2 glutathione S-transferase, alpha 2 (Yc2) increases expression ISO Chlormequat results in increased expression of GSTA2 protein CTD PMID:34958886 NCBI chr 9:78,238,300...78,254,474
Ensembl chr 9:78,238,300...78,263,070
JBrowse link
G Gtf2h5 general transcription factor IIH, polypeptide 5 increases expression ISO Chlormequat results in increased expression of GTF2H5 protein CTD PMID:34958886 NCBI chr17:6,130,103...6,135,763
Ensembl chr17:6,130,061...6,136,792
JBrowse link
G H1f0 H1.0 linker histone increases expression ISO Chlormequat results in increased expression of H1-0 protein CTD PMID:34958886 NCBI chr15:78,912,412...78,914,704
Ensembl chr15:78,912,650...78,914,704
JBrowse link
G H1f5 H1.5 linker histone, cluster member increases expression ISO Chlormequat results in increased expression of H1-5 protein CTD PMID:34958886 NCBI chr13:21,964,002...21,964,795
Ensembl chr13:21,964,053...21,964,795
JBrowse link
G Hebp2 heme binding protein 2 increases expression ISO Chlormequat results in increased expression of HEBP2 protein CTD PMID:34958886 NCBI chr10:18,415,871...18,421,824
Ensembl chr10:18,415,246...18,421,824
JBrowse link
G Herpud2 HERPUD family member 2 increases expression ISO Chlormequat results in increased expression of HERPUD2 protein CTD PMID:34958886 NCBI chr 9:25,012,412...25,063,109
Ensembl chr 9:25,019,428...25,063,116
JBrowse link
G Hnrnpc heterogeneous nuclear ribonucleoprotein C increases expression ISO Chlormequat results in increased expression of HNRNPC protein CTD PMID:34958886 NCBI chr14:52,310,834...52,341,462
Ensembl chr14:52,310,834...52,341,485
JBrowse link
G Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 decreases expression ISO Chlormequat results in decreased expression of HSD3B1 protein CTD PMID:29447956 NCBI chr 3:98,749,672...98,767,110
Ensembl chr 3:98,759,510...98,767,110
JBrowse link
G Hspa5 heat shock protein 5 increases expression
multiple interactions
ISO Chlormequat results in increased expression of HSPA5 protein
4-phenylbutyric acid inhibits the reaction [Chlormequat results in increased expression of HSPA5 protein]
CTD PMID:34958886 NCBI chr 2:34,662,102...34,666,541
Ensembl chr 2:34,661,982...34,667,559
JBrowse link
G Igf1 insulin-like growth factor 1 affects expression
increases expression
ISO Chlormequat affects the expression of IGF1 protein
Chlormequat results in increased expression of IGF1 protein
CTD PMID:28214531 PMID:31704167 NCBI chr10:87,694,127...87,772,909
Ensembl chr10:87,694,127...87,772,904
JBrowse link
G Ina internexin neuronal intermediate filament protein, alpha decreases expression ISO Chlormequat results in decreased expression of INA protein CTD PMID:34958886 NCBI chr19:47,003,120...47,013,766
Ensembl chr19:47,003,137...47,013,766
JBrowse link
G Itgb1bp1 integrin beta 1 binding protein 1 increases expression ISO Chlormequat results in increased expression of ITGB1BP1 protein CTD PMID:34958886 NCBI chr12:21,317,247...21,336,285
Ensembl chr12:21,290,826...21,336,285
JBrowse link
G Kazn kazrin, periplakin interacting protein increases expression ISO Chlormequat results in increased expression of KAZN protein CTD PMID:34958886 NCBI chr 4:141,829,701...142,801,231
Ensembl chr 4:141,829,701...142,205,056
JBrowse link
G Klhl26 kelch-like 26 decreases expression ISO Chlormequat results in decreased expression of KLHL26 protein CTD PMID:34958886 NCBI chr 8:70,902,868...70,929,660
Ensembl chr 8:70,902,869...70,929,618
JBrowse link
G Klhl7 kelch-like 7 decreases expression ISO Chlormequat results in decreased expression of KLHL7 protein CTD PMID:34958886 NCBI chr 5:24,305,563...24,368,363
Ensembl chr 5:24,305,603...24,365,790
JBrowse link
G Ldb1 LIM domain binding 1 increases expression ISO Chlormequat results in increased expression of LDB1 protein CTD PMID:34958886 NCBI chr19:46,019,963...46,036,584
Ensembl chr19:46,020,009...46,033,653
JBrowse link
G Lhb luteinizing hormone beta increases expression ISO Chlormequat results in increased expression of LHB protein CTD PMID:29447956 NCBI chr 7:45,070,370...45,071,278
Ensembl chr 7:45,070,244...45,071,321
JBrowse link
G Lrrc7 leucine rich repeat containing 7 increases expression ISO Chlormequat results in increased expression of LRRC7 protein CTD PMID:34958886 NCBI chr 3:157,772,823...158,268,254
Ensembl chr 3:157,788,528...158,267,858
Ensembl chr 3:157,788,528...158,267,858
JBrowse link
G Macroh2a1 macroH2A.1 histone increases expression ISO Chlormequat results in increased expression of MACROH2A1 protein CTD PMID:34958886 NCBI chr13:56,221,435...56,283,439
Ensembl chr13:56,221,432...56,284,174
JBrowse link
G Macroh2a2 macroH2A.2 histone increases expression ISO Chlormequat results in increased expression of MACROH2A2 protein CTD PMID:34958886 NCBI chr10:61,574,419...61,620,383
Ensembl chr10:61,574,444...61,619,926
JBrowse link
G Map4 microtubule-associated protein 4 decreases expression ISO Chlormequat results in decreased expression of MAP4 protein CTD PMID:34958886 NCBI chr 9:109,758,909...109,913,018
Ensembl chr 9:109,760,528...109,913,023
JBrowse link
G Mgat4b mannoside acetylglucosaminyltransferase 4, isoenzyme B increases expression ISO Chlormequat results in increased expression of MGAT4B protein CTD PMID:34958886 NCBI chr11:50,116,162...50,125,930
Ensembl chr11:50,101,717...50,125,930
JBrowse link
G Mospd3 motile sperm domain containing 3 decreases expression ISO Chlormequat results in decreased expression of MOSPD3 protein CTD PMID:34958886 NCBI chr 5:137,594,907...137,599,342
Ensembl chr 5:137,594,907...137,599,320
JBrowse link
G Mov10 Mov10 RISC complex RNA helicase increases expression ISO Chlormequat results in increased expression of MOV10 protein CTD PMID:34958886 NCBI chr 3:104,702,144...104,725,935
Ensembl chr 3:104,702,152...104,725,879
JBrowse link
G Mpp2 membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2) decreases expression ISO Chlormequat results in decreased expression of MPP2 protein CTD PMID:34958886 NCBI chr11:101,947,841...101,979,464
Ensembl chr11:101,947,841...101,979,341
JBrowse link
G Mpv17l2 MPV17 mitochondrial membrane protein-like 2 increases expression ISO Chlormequat results in increased expression of MPV17L2 protein CTD PMID:34958886 NCBI chr 8:71,211,295...71,213,589
Ensembl chr 8:71,211,295...71,213,592
JBrowse link
G Mrpl51 mitochondrial ribosomal protein L51 increases expression ISO Chlormequat results in increased expression of MRPL51 protein CTD PMID:34958886 NCBI chr 6:125,169,163...125,171,355
Ensembl chr 6:125,168,764...125,173,232
JBrowse link
G Mrpl54 mitochondrial ribosomal protein L54 increases expression ISO Chlormequat results in increased expression of MRPL54 protein CTD PMID:34958886 NCBI chr10:81,100,556...81,102,760
Ensembl chr10:81,100,547...81,102,768
JBrowse link
G Mrps14 mitochondrial ribosomal protein S14 increases expression ISO Chlormequat results in increased expression of MRPS14 protein CTD PMID:34958886 NCBI chr 1:160,022,785...160,028,756
Ensembl chr 1:160,022,785...160,029,740
JBrowse link
G Mtrfr mitochondrial translation release factor in rescue increases expression ISO Chlormequat results in increased expression of MTRFR protein CTD PMID:34958886 NCBI chr 5:124,466,152...124,479,915
Ensembl chr 5:124,466,152...124,479,907
JBrowse link
G Ncl nucleolin increases expression ISO Chlormequat results in increased expression of NCL protein CTD PMID:34958886 NCBI chr 1:86,272,441...86,287,177
Ensembl chr 1:86,272,441...86,287,122
JBrowse link
G Nipa1 non imprinted in Prader-Willi/Angelman syndrome 1 homolog (human) decreases expression ISO Chlormequat results in decreased expression of NIPA1 protein CTD PMID:34958886 NCBI chr 7:55,628,232...55,669,348
Ensembl chr 7:55,627,315...55,669,702
JBrowse link
G Npr3 natriuretic peptide receptor 3 decreases expression ISO Chlormequat results in decreased expression of NPR3 protein CTD PMID:34958886 NCBI chr15:11,839,982...11,907,287
Ensembl chr15:11,839,982...11,907,373
JBrowse link
G Nr3c2 nuclear receptor subfamily 3, group C, member 2 increases expression ISO Chlormequat results in increased expression of NR3C2 protein CTD PMID:34958886 NCBI chr 8:77,626,422...77,971,641
Ensembl chr 8:77,626,070...77,971,641
JBrowse link
G Orai1 ORAI calcium release-activated calcium modulator 1 increases expression ISO Chlormequat results in increased expression of ORAI1 protein CTD PMID:34958886 NCBI chr 5:123,153,078...123,168,515
Ensembl chr 5:123,153,137...123,168,519
JBrowse link
G Pabpc1 poly(A) binding protein, cytoplasmic 1 increases expression ISO Chlormequat results in increased expression of PABPC1 protein CTD PMID:34958886 NCBI chr15:36,595,902...36,609,825
Ensembl chr15:36,595,905...36,609,912
JBrowse link
G Pabpc4 poly(A) binding protein, cytoplasmic 4 increases expression ISO Chlormequat results in increased expression of PABPC4 protein CTD PMID:34958886 NCBI chr 4:123,172,722...123,192,718
Ensembl chr 4:123,156,144...123,192,718
JBrowse link
G Pccb propionyl Coenzyme A carboxylase, beta polypeptide increases expression ISO Chlormequat results in increased expression of PCCB protein CTD PMID:34958886 NCBI chr 9:100,864,085...100,916,993
Ensembl chr 9:100,864,085...100,916,951
JBrowse link
G Pex26 peroxisomal biogenesis factor 26 increases expression ISO Chlormequat results in increased expression of PEX26 protein CTD PMID:34958886 NCBI chr 6:121,160,176...121,175,796
Ensembl chr 6:121,160,626...121,175,796
JBrowse link
G Pgpep1 pyroglutamyl-peptidase I increases expression ISO Chlormequat results in increased expression of PGPEP1 protein CTD PMID:34958886 NCBI chr 8:71,099,086...71,113,096
Ensembl chr 8:71,099,085...71,113,038
JBrowse link
G Phldb1 pleckstrin homology like domain, family B, member 1 increases expression ISO Chlormequat results in increased expression of PHLDB1 protein CTD PMID:34958886 NCBI chr 9:44,597,605...44,649,800
Ensembl chr 9:44,597,601...44,646,495
JBrowse link
G Pias3 protein inhibitor of activated STAT 3 decreases expression ISO Chlormequat results in decreased expression of PIAS3 protein CTD PMID:34958886 NCBI chr 3:96,603,679...96,613,386
Ensembl chr 3:96,603,700...96,613,386
JBrowse link
G Pik3cd phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta increases expression ISO Chlormequat results in increased expression of PIK3CD protein CTD PMID:34958886 NCBI chr 4:149,733,625...149,787,023
Ensembl chr 4:149,733,625...149,787,028
JBrowse link
G Pitpnm2 phosphatidylinositol transfer protein, membrane-associated 2 increases expression ISO Chlormequat results in increased expression of PITPNM2 protein CTD PMID:34958886 NCBI chr 5:124,256,753...124,387,973
Ensembl chr 5:124,256,753...124,387,823
JBrowse link
G Pole4 polymerase (DNA-directed), epsilon 4 (p12 subunit) increases expression ISO Chlormequat results in increased expression of POLE4 protein CTD PMID:34958886 NCBI chr 6:82,593,513...82,629,985
Ensembl chr 6:82,595,973...82,682,346
JBrowse link
G Pou1f1 POU domain, class 1, transcription factor 1 increases expression ISO Chlormequat results in increased expression of POU1F1 protein CTD PMID:38552810 NCBI chr16:65,317,398...65,331,904
Ensembl chr16:65,317,397...65,331,183
JBrowse link
G Pphln1 periphilin 1 increases expression ISO Chlormequat results in increased expression of PPHLN1 protein CTD PMID:34958886 NCBI chr15:93,296,243...93,389,794
Ensembl chr15:93,296,231...93,389,391
JBrowse link
G Prkaca protein kinase, cAMP dependent, catalytic, alpha affects expression ISO Chlormequat affects the expression of PRKACA protein CTD PMID:38552810 NCBI chr 8:84,699,607...84,723,073
Ensembl chr 8:84,699,622...84,723,072
JBrowse link
G Prkar1b protein kinase, cAMP dependent regulatory, type I beta increases expression ISO Chlormequat results in increased expression of PRKAR1B protein CTD PMID:34958886 NCBI chr 5:139,003,059...139,136,458
Ensembl chr 5:139,003,061...139,135,756
JBrowse link
G Psmb7 proteasome (prosome, macropain) subunit, beta type 7 increases expression ISO Chlormequat results in increased expression of PSMB7 protein CTD PMID:34958886 NCBI chr 2:38,478,058...38,533,964
Ensembl chr 2:38,478,048...38,534,099
JBrowse link
G Rab6a RAB6A, member RAS oncogene family increases expression ISO Chlormequat results in increased expression of RAB6A protein CTD PMID:34958886 NCBI chr 7:100,256,778...100,290,475
Ensembl chr 7:100,256,617...100,290,475
JBrowse link
G Rad17 RAD17 checkpoint clamp loader component increases expression ISO Chlormequat results in increased expression of RAD17 protein CTD PMID:34958886 NCBI chr13:100,753,672...100,787,569
Ensembl chr13:100,753,672...100,787,559
JBrowse link
G Rhoq ras homolog family member Q increases expression ISO Chlormequat results in increased expression of RHOQ protein CTD PMID:34958886 NCBI chr17:87,270,539...87,307,497
Ensembl chr17:87,270,510...87,307,497
JBrowse link
G Rnf113a1 ring finger protein 113A1 decreases expression ISO Chlormequat results in decreased expression of RNF113A1 protein CTD PMID:34958886 NCBI chr  X:36,454,875...36,456,120
Ensembl chr  X:36,454,898...36,456,120
JBrowse link
G Rnf185 ring finger protein 185 increases expression
multiple interactions
ISO Chlormequat results in increased expression of RNF185 protein
4-phenylbutyric acid inhibits the reaction [Chlormequat results in increased expression of RNF185 protein]
CTD PMID:34958886 NCBI chr11:3,365,973...3,402,956
Ensembl chr11:3,365,982...3,402,363
JBrowse link
G Rspry1 ring finger and SPRY domain containing 1 increases expression ISO Chlormequat results in increased expression of RSPRY1 protein CTD PMID:34958886 NCBI chr 8:95,328,569...95,386,905
Ensembl chr 8:95,328,565...95,386,903
JBrowse link
G Rtn1 reticulon 1 decreases expression ISO Chlormequat results in decreased expression of RTN1 protein CTD PMID:34958886 NCBI chr12:72,258,523...72,455,828
Ensembl chr12:72,258,526...72,455,828
JBrowse link
G S100a1 S100 calcium binding protein A1 increases expression ISO Chlormequat results in increased expression of S100A1 protein CTD PMID:34958886 NCBI chr 3:90,418,341...90,421,637
Ensembl chr 3:90,418,341...90,421,699
JBrowse link
G Samd8 sterile alpha motif domain containing 8 increases expression ISO Chlormequat results in increased expression of SAMD8 protein CTD PMID:34958886 NCBI chr14:21,800,599...21,848,794
Ensembl chr14:21,800,599...21,848,794
JBrowse link
G Sar1a secretion associated Ras related GTPase 1A increases expression ISO Chlormequat results in increased expression of SAR1A protein CTD PMID:34958886 NCBI chr10:61,516,096...61,529,076
Ensembl chr10:61,516,078...61,529,076
JBrowse link
G Shroom1 shroom family member 1 decreases expression ISO Chlormequat results in decreased expression of SHROOM1 protein CTD PMID:34958886 NCBI chr11:53,347,904...53,358,593
Ensembl chr11:53,348,032...53,358,593
JBrowse link
G Ski ski sarcoma viral oncogene homolog (avian) increases expression ISO Chlormequat results in increased expression of SKI protein CTD PMID:34958886 NCBI chr 4:155,238,532...155,307,536
Ensembl chr 4:155,238,532...155,307,049
JBrowse link
G Slc48a1 solute carrier family 48 (heme transporter), member 1 decreases expression ISO Chlormequat results in decreased expression of SLC48A1 protein CTD PMID:34958886 NCBI chr15:97,682,246...97,690,573
Ensembl chr15:97,676,401...97,690,573
JBrowse link
G Slit3 slit guidance ligand 3 increases expression ISO Chlormequat results in increased expression of SLIT3 protein CTD PMID:34958886 NCBI chr11:35,012,283...35,599,334
Ensembl chr11:35,012,051...35,599,334
JBrowse link
G Slu7 SLU7 splicing factor homolog (S. cerevisiae) increases expression ISO Chlormequat results in increased expression of SLU7 protein CTD PMID:34958886 NCBI chr11:43,324,550...43,338,809
Ensembl chr11:43,324,571...43,338,808
JBrowse link
G Smim26 small integral membrane protein 26 decreases expression ISO Chlormequat results in decreased expression of SMIM26 protein CTD PMID:34958886 NCBI chr 2:144,435,985...144,437,286
Ensembl chr 2:144,435,974...144,437,286
JBrowse link
G Spns1 SPNS lysolipid transporter 1, lysophospholipid increases expression ISO Chlormequat results in increased expression of SPNS1 protein CTD PMID:34958886 NCBI chr 7:125,969,232...125,977,179
Ensembl chr 7:125,969,232...125,976,622
JBrowse link
G Sppl2b signal peptide peptidase like 2B increases expression ISO Chlormequat results in increased expression of SPPL2B protein CTD PMID:34958886 NCBI chr10:80,691,067...80,704,542
Ensembl chr10:80,691,109...80,704,542
JBrowse link
G Sst somatostatin affects expression ISO Chlormequat affects the expression of SST protein CTD PMID:38552810 NCBI chr16:23,708,327...23,710,041
Ensembl chr16:23,708,323...23,709,708
JBrowse link
G St3gal1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 increases expression ISO Chlormequat results in increased expression of ST3GAL1 protein CTD PMID:34958886 NCBI chr15:66,974,724...67,048,575
Ensembl chr15:66,974,724...67,048,679
JBrowse link
G St7l suppression of tumorigenicity 7-like decreases expression ISO Chlormequat results in decreased expression of ST7L protein CTD PMID:34958886 NCBI chr 3:104,771,822...104,837,384
Ensembl chr 3:104,771,321...104,837,380
JBrowse link
G Star steroidogenic acute regulatory protein decreases expression ISO Chlormequat results in decreased expression of STAR protein CTD PMID:29447956 NCBI chr 8:26,298,502...26,306,010
Ensembl chr 8:26,296,583...26,306,010
JBrowse link
G Stk26 serine/threonine kinase 26 increases expression ISO Chlormequat results in increased expression of STK26 protein CTD PMID:34958886 NCBI chr  X:49,930,052...49,981,980
Ensembl chr  X:49,929,924...49,981,974
JBrowse link
G Susd2 sushi domain containing 2 increases expression ISO Chlormequat results in increased expression of SUSD2 protein CTD PMID:34958886 NCBI chr10:75,472,453...75,479,842
Ensembl chr10:75,472,540...75,479,842
JBrowse link
G Taf7 TATA-box binding protein associated factor 7 increases expression ISO Chlormequat results in increased expression of TAF7 protein CTD PMID:34958886 NCBI chr18:37,773,544...37,777,257
Ensembl chr18:37,773,544...37,777,257
JBrowse link
G Tcaf1 TRPM8 channel-associated factor 1 increases expression ISO Chlormequat results in increased expression of TCAF1 protein CTD PMID:34958886 NCBI chr 6:42,644,933...42,687,065
Ensembl chr 6:42,644,936...42,687,022
JBrowse link
G Tceanc transcription elongation factor A (SII) N-terminal and central domain containing decreases expression ISO Chlormequat results in decreased expression of TCEANC protein CTD PMID:34958886 NCBI chr  X:165,282,806...165,301,594
Ensembl chr  X:165,282,808...165,301,563
JBrowse link
G Tent2 terminal nucleotidyltransferase 2 increases expression ISO Chlormequat results in increased expression of TENT2 protein CTD PMID:34958886 NCBI chr13:93,282,363...93,330,662
Ensembl chr13:93,282,790...93,328,893
JBrowse link
G Them4 thioesterase superfamily member 4 decreases expression ISO Chlormequat results in decreased expression of THEM4 protein CTD PMID:34958886 NCBI chr 3:94,217,415...94,239,847
Ensembl chr 3:94,217,396...94,239,847
JBrowse link
G Thoc6 THO complex 6 increases expression ISO Chlormequat results in increased expression of THOC6 protein CTD PMID:34958886 NCBI chr17:23,887,592...23,892,891
Ensembl chr17:23,887,588...23,892,856
JBrowse link
G Tirap toll-interleukin 1 receptor (TIR) domain-containing adaptor protein increases expression ISO Chlormequat results in increased expression of TIRAP protein CTD PMID:34958886 NCBI chr 9:35,095,687...35,111,587
Ensembl chr 9:35,095,847...35,111,587
JBrowse link
G Tkt transketolase increases expression ISO Chlormequat results in increased expression of TKT protein CTD PMID:34958886 NCBI chr14:30,271,088...30,296,681
Ensembl chr14:30,270,316...30,296,677
JBrowse link
G Tmem106c transmembrane protein 106C increases expression ISO Chlormequat results in increased expression of TMEM106C protein CTD PMID:34958886 NCBI chr15:97,862,077...97,868,158
Ensembl chr15:97,862,081...97,868,156
JBrowse link
G Tmem184c transmembrane protein 184C decreases expression ISO Chlormequat results in decreased expression of TMEM184C protein CTD PMID:34958886 NCBI chr 8:78,322,607...78,337,343
Ensembl chr 8:78,322,611...78,337,327
JBrowse link
G Tmem208 transmembrane protein 208 increases expression ISO Chlormequat results in increased expression of TMEM208 protein CTD PMID:34958886 NCBI chr 8:106,052,980...106,062,117
Ensembl chr 8:106,052,986...106,061,851
JBrowse link
G Tmem222 transmembrane protein 222 increases expression ISO Chlormequat results in increased expression of TMEM222 protein CTD PMID:34958886 NCBI chr 4:132,993,356...133,005,101
Ensembl chr 4:132,993,356...133,005,103
JBrowse link
G Tnfsf11 tumor necrosis factor (ligand) superfamily, member 11 affects expression ISO Chlormequat affects the expression of TNFSF11 mRNA CTD PMID:28214531 NCBI chr14:78,514,886...78,545,483
Ensembl chr14:78,514,885...78,545,483
JBrowse link
G Tra2a transformer 2 alpha increases expression ISO Chlormequat results in increased expression of TRA2A protein CTD PMID:34958886 NCBI chr 6:49,220,855...49,241,182
Ensembl chr 6:49,220,858...49,240,967
JBrowse link
G Tram2 translocating chain-associating membrane protein 2 decreases expression ISO Chlormequat results in decreased expression of TRAM2 protein CTD PMID:34958886 NCBI chr 1:21,071,621...21,149,449
Ensembl chr 1:21,066,523...21,149,453
JBrowse link
G Trp53i11 transformation related protein 53 inducible protein 11 increases expression ISO Chlormequat results in increased expression of TP53I11 protein CTD PMID:34958886 NCBI chr 2:93,017,694...93,032,102
Ensembl chr 2:93,017,893...93,032,104
JBrowse link
G Ttc12 tetratricopeptide repeat domain 12 increases expression ISO Chlormequat results in increased expression of TTC12 protein CTD PMID:34958886 NCBI chr 9:49,348,261...49,397,572
Ensembl chr 9:49,348,263...49,397,525
JBrowse link
G Ube2d1 ubiquitin-conjugating enzyme E2D 1 multiple interactions
increases expression
ISO 4-phenylbutyric acid inhibits the reaction [Chlormequat results in increased expression of UBE2D1 protein] CTD PMID:34958886 NCBI chr10:71,090,810...71,121,048
Ensembl chr10:71,090,810...71,121,092
JBrowse link
G Ucp2 uncoupling protein 2 (mitochondrial, proton carrier) decreases expression ISO Chlormequat results in decreased expression of UCP2 protein CTD PMID:34958886 NCBI chr 7:100,142,565...100,148,832
Ensembl chr 7:100,142,544...100,151,227
JBrowse link
G Wdr74 WD repeat domain 74 increases expression ISO Chlormequat results in increased expression of WDR74 protein CTD PMID:34958886 NCBI chr19:8,713,159...8,717,988
Ensembl chr19:8,713,191...8,717,988
JBrowse link
G Wsb2 WD repeat and SOCS box-containing 2 decreases expression ISO Chlormequat results in decreased expression of WSB2 protein CTD PMID:34958886 NCBI chr 5:117,495,370...117,516,666
Ensembl chr 5:117,495,369...117,516,666
JBrowse link
G Zeb1 zinc finger E-box binding homeobox 1 increases expression ISO Chlormequat results in increased expression of ZEB1 protein CTD PMID:34958886 NCBI chr18:5,591,330...5,775,468
Ensembl chr18:5,591,860...5,775,467
JBrowse link
cocaine hydrochloride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmal1 basic helix-loop-helix ARNT like 1 decreases expression EXP cocaine hydrochloride decreases expression of Bmal1 mRNA in caudate-putamen RGD PMID:15994025 RGD:405866348 NCBI chr 7:112,777,820...112,913,333
Ensembl chr 7:112,806,672...112,913,333
JBrowse link
G Clock clock circadian regulator increases expression EXP cocaine hydrochloride increases expression of Clock mRNA in caudate-putamen RGD PMID:15994025 RGD:405866348 NCBI chr 5:76,357,715...76,452,675
Ensembl chr 5:76,357,715...76,452,639
JBrowse link
G Cry1 cryptochrome circadian regulator 1 decreases expression
increases expression
EXP cocaine hydrochloride decreases expression of Cry1 mRNA in caudate-putamen
cocaine hydrochloride increases expression of Cry1 mRNA in hippocampal formation
RGD PMID:15994025 PMID:15994025 RGD:405866347, RGD:405866347 NCBI chr10:84,967,564...85,020,918
Ensembl chr10:84,967,564...85,020,928
JBrowse link
G Cry2 cryptochrome circadian regulator 2 decreases expression EXP cocaine hydrochloride decreases expression of Cry2 mRNA in caudate-putamen RGD PMID:15994025 RGD:405866347 NCBI chr 2:92,233,991...92,264,426
Ensembl chr 2:92,233,991...92,264,388
JBrowse link
G Npas2 neuronal PAS domain protein 2 decreases expression EXP cocaine hydrochloride decreases expression of hippocampal formation and caudate-putamen RGD PMID:15994025 RGD:405866347 NCBI chr 1:39,233,013...39,402,321
Ensembl chr 1:39,232,812...39,402,317
JBrowse link
G Per1 period circadian clock 1 increases expression EXP cocaine hydrochloride increases expression of Per1 mRNA in hippocampal formation and caudate-putamen RGD PMID:15994025 RGD:405866348 NCBI chr11:68,985,934...69,000,791
Ensembl chr11:68,986,043...69,000,786
JBrowse link
G Per2 period circadian clock 2 increases expression
decreases expression
EXP ocaine hydrochloride increases expression of Per2 mRNA in hippocampal formation
cocaine hydrochloride decreases expression of Per2 mRNA in caudate-putamen
RGD PMID:15994025 PMID:15994025 RGD:405866348, RGD:405866348 NCBI chr 1:91,343,699...91,387,028
Ensembl chr 1:91,343,704...91,387,046
JBrowse link
G Per3 period circadian clock 3 increases expression EXP cocaine hydrochloride increases expression of Per3 mRNA in hippocampal formation and caudate-putamen RGD PMID:15994025 RGD:405866348 NCBI chr 4:151,081,475...151,129,167
Ensembl chr 4:151,088,109...151,129,122
JBrowse link
colesevelam hydrochloride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Crp C-reactive protein, pentraxin-related decreases expression ISO Colesevelam Hydrochloride results in decreased expression of CRP protein CTD PMID:16616026 NCBI chr 1:172,525,623...172,527,533
Ensembl chr 1:172,525,622...172,660,598
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-Coenzyme A reductase multiple interactions
increases expression
EXP Colesevelam Hydrochloride promotes the reaction [Simvastatin results in increased expression of HMGCR mRNA]
Colesevelam Hydrochloride results in increased expression of HMGCR mRNA
CTD PMID:22120639 NCBI chr13:96,785,470...96,807,444
Ensembl chr13:96,785,475...96,807,444
JBrowse link
G Ldlr low density lipoprotein receptor increases expression EXP Colesevelam Hydrochloride results in increased expression of LDLR mRNA CTD PMID:22120639 NCBI chr 9:21,634,872...21,661,215
Ensembl chr 9:21,634,779...21,661,215
JBrowse link
colforsin daropate hydrochloride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca1 ATP-binding cassette, sub-family A member 1 multiple interactions ISO Colforsin promotes the reaction [Diethylhexyl Phthalate results in decreased expression of ABCA1 mRNA] CTD PMID:37536456 NCBI chr 4:53,030,789...53,159,988
Ensembl chr 4:53,030,787...53,159,895
JBrowse link
G Abcb1a ATP-binding cassette, sub-family B member 1A increases expression
multiple interactions
ISO Colforsin results in increased expression of ABCB1 mRNA
N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Colforsin results in increased expression of ABCB1 mRNA]
CTD PMID:12926078 NCBI chr 5:8,617,091...8,798,575
Ensembl chr 5:8,710,077...8,798,575
JBrowse link
G Abcb4 ATP-binding cassette, sub-family B member 4 multiple interactions
decreases expression
ISO Colforsin inhibits the reaction [Doxorubicin results in increased expression of ABCB4 mRNA]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Colforsin results in decreased expression of ABCB4 mRNA] CTD PMID:12926078 NCBI chr 5:8,943,614...9,009,226
Ensembl chr 5:8,943,717...9,009,231
JBrowse link
G Abcc2 ATP-binding cassette, sub-family member 2 increases expression ISO Colforsin results in increased expression of ABCC2 mRNA; Colforsin results in increased expression of ABCC2 protein CTD PMID:19580841 PMID:26049102 NCBI chr19:43,770,747...43,826,771
Ensembl chr19:43,770,631...43,829,179
JBrowse link
G Abcc4 ATP-binding cassette, sub-family C member 4 decreases expression
multiple interactions
ISO Colforsin results in decreased expression of ABCC4 mRNA
Valproic Acid inhibits the reaction [Colforsin results in decreased expression of ABCC4 mRNA]
CTD PMID:37385477 NCBI chr14:118,720,104...118,945,475
Ensembl chr14:118,720,104...118,943,631
JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 (Junior blood group) increases expression
multiple interactions
ISO Colforsin results in increased expression of ABCG2 mRNA
Colforsin inhibits the reaction [anandamide inhibits the reaction [CREB1 protein modified form binds to ABCG2 promoter]]
CTD PMID:19580841 PMID:30610963 NCBI chr 6:58,561,476...58,669,436
Ensembl chr 6:58,561,508...58,672,661
JBrowse link
G Acaca acetyl-Coenzyme A carboxylase alpha increases phosphorylation EXP Colforsin results in increased phosphorylation of ACACA protein CTD PMID:18390901 NCBI chr11:84,020,461...84,292,477
Ensembl chr11:84,020,498...84,292,477
JBrowse link
G Ache acetylcholinesterase increases activity
increases expression
ISO Colforsin results in increased activity of ACHE protein; Colforsin results in increased activity of ACHE protein alternative form
Colforsin results in increased expression of ACHE mRNA
CTD PMID:18514641 NCBI chr 5:137,286,516...137,292,728
Ensembl chr 5:137,285,781...137,292,728
JBrowse link
G Acsl3 acyl-CoA synthetase long-chain family member 3 increases expression ISO Colforsin results in increased expression of ACSL3 mRNA CTD PMID:16751804 NCBI chr 1:78,635,600...78,685,462
Ensembl chr 1:78,635,542...78,685,460
JBrowse link
G Acta2 actin alpha 2, smooth muscle, aorta decreases expression
multiple interactions
ISO Colforsin results in decreased expression of ACTA2 protein
Colforsin inhibits the reaction [Carbon Tetrachloride results in increased expression of ACTA2 protein]
CTD PMID:21603974 PMID:27590029 NCBI chr19:34,217,736...34,232,985
Ensembl chr19:34,218,490...34,232,990
JBrowse link
G Adam12 ADAM metallopeptidase domain 12 decreases expression ISO Colforsin results in decreased expression of ADAM12 mRNA CTD PMID:15313392 PMID:15967414 NCBI chr 7:133,484,928...133,826,859
Ensembl chr 7:133,484,928...133,833,875
JBrowse link
G Adamts1 ADAM metallopeptidase with thrombospondin type 1 motif 1 decreases expression ISO Colforsin results in decreased expression of ADAMTS1 mRNA CTD PMID:15313392 PMID:15967414 NCBI chr16:85,590,715...85,600,001
Ensembl chr16:85,590,715...85,600,001
JBrowse link
G Adcy5 adenylate cyclase 5 multiple interactions EXP ADCY5 protein results in increased susceptibility to [Colforsin co-treated with Quinpirole] CTD PMID:12223546 NCBI chr16:34,974,933...35,126,108
Ensembl chr16:34,975,247...35,126,108
JBrowse link
G Adcy6 adenylate cyclase 6 affects response to substance EXP ADCY6 protein affects the susceptibility to Colforsin CTD PMID:12393090 NCBI chr15:98,484,982...98,508,119
Ensembl chr15:98,487,854...98,507,957
JBrowse link
G Adcy9 adenylate cyclase 9 increases activity
multiple interactions
EXP Colforsin results in increased activity of ADCY9 protein
[Colforsin co-treated with Miconazole] results in increased activity of ADCY9 protein
CTD PMID:30607468 NCBI chr16:4,102,750...4,255,094
Ensembl chr16:4,105,393...4,238,362
JBrowse link
G Adm adrenomedullin multiple interactions
increases expression
ISO cobaltous chloride inhibits the reaction [Valproic Acid inhibits the reaction [Colforsin results in increased expression of ADM mRNA]]; Valproic Acid inhibits the reaction [Colforsin results in increased expression of ADM mRNA] CTD PMID:38296531 NCBI chr 7:110,226,864...110,229,027
Ensembl chr 7:110,226,868...110,229,027
JBrowse link
G Adra1a adrenergic receptor, alpha 1a multiple interactions ISO [Colforsin co-treated with 1-Methyl-3-isobutylxanthine] affects the reaction [[Phenylephrine binds to and results in increased activity of ADRA1A protein] which affects the transport of Potassium] CTD PMID:19419905 NCBI chr14:66,872,705...67,009,549
Ensembl chr14:66,872,700...67,008,617
JBrowse link
G Adra2c adrenergic receptor, alpha 2c multiple interactions
affects localization
increases expression
ISO AKAP13 protein modified form affects the reaction [Colforsin affects the localization of ADRA2C protein]; AKAP13 protein modified form affects the reaction [Colforsin results in increased expression of ADRA2C mRNA] CTD PMID:24701590 NCBI chr 5:35,435,910...35,439,107
Ensembl chr 5:35,435,663...35,439,107
JBrowse link
G Adrb1 adrenergic receptor, beta 1 affects response to substance
multiple interactions
ISO ADRB1 protein polymorphism affects the susceptibility to Colforsin
[[Colforsin co-treated with 1-Methyl-3-isobutylxanthine] results in increased activity of [ADRB1 protein binds to ADRB2 protein]] affects the reaction [KCNH2 protein results in increased transport of Potassium]; [Colforsin co-treated with 1-Methyl-3-isobutylxanthine] promotes the reaction [[ADRB1 protein binds to ADRB2 protein] which results in increased abundance of Cyclic AMP]; [Colforsin co-treated with 1-Methyl-3-isobutylxanthine] results in increased activity of [ADRB1 protein binds to ADRB2 protein]
CTD PMID:14502278 PMID:19419905 NCBI chr19:56,710,549...56,713,582
Ensembl chr19:56,710,631...56,721,545
JBrowse link
G Adrb2 adrenergic receptor, beta 2 multiple interactions
increases expression
increases phosphorylation
ISO [[Colforsin co-treated with 1-Methyl-3-isobutylxanthine] results in increased activity of [ADRB1 protein binds to ADRB2 protein]] affects the reaction [KCNH2 protein results in increased transport of Potassium]; [Colforsin co-treated with 1-Methyl-3-isobutylxanthine] promotes the reaction [[ADRB1 protein binds to ADRB2 protein] which results in increased abundance of Cyclic AMP]; [Colforsin co-treated with 1-Methyl-3-isobutylxanthine] results in increased activity of [ADRB1 protein binds to ADRB2 protein]
Colforsin results in increased expression of ADRB2 mRNA
Colforsin results in increased phosphorylation of ADRB2 protein
CTD PMID:14722251 PMID:19419905 PMID:24705868 NCBI chr18:62,310,784...62,313,052
Ensembl chr18:62,310,887...62,313,030
JBrowse link
G Adrb3 adrenergic receptor, beta 3 decreases expression EXP Colforsin results in decreased expression of ADRB3 mRNA CTD PMID:10725275 NCBI chr 8:27,715,804...27,720,833
Ensembl chr 8:27,715,804...27,740,644
JBrowse link
G Ahr aryl-hydrocarbon receptor multiple interactions
affects localization
ISO
EXP
[Colforsin results in increased activity of AHR protein] which results in increased expression of CXCL8 mRNA; [Colforsin results in increased activity of AHR protein] which results in increased expression of CXCL8 protein; [Colforsin results in increased activity of AHR protein] which results in increased secretion of CXCL8 protein; Colforsin promotes the reaction [[AHR protein binds to RELB protein] which binds to CXCL8 promoter]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Colforsin promotes the reaction [[AHR protein binds to RELB protein] which binds to CXCL8 promoter]]; PDE2A protein inhibits the reaction [Colforsin affects the localization of AHR protein]
AHR protein inhibits the reaction [[Colforsin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of PER1 mRNA]
CTD PMID:15972329 PMID:17329248 PMID:17823304 PMID:23291558 NCBI chr12:35,547,978...35,584,988
Ensembl chr12:35,547,973...35,585,037
JBrowse link
G Akap13 A kinase anchor protein 13 multiple interactions ISO AKAP13 protein modified form affects the reaction [Colforsin affects the localization of ADRA2C protein]; AKAP13 protein modified form affects the reaction [Colforsin results in increased expression of ADRA2C mRNA]; AKAP13 protein modified form inhibits the reaction [Colforsin results in increased phosphorylation of CREB1 protein] CTD PMID:24701590 NCBI chr 7:75,105,271...75,404,357
Ensembl chr 7:75,105,282...75,404,357
JBrowse link
G Akr1c18 aldo-keto reductase family 1, member C18 decreases expression ISO Colforsin results in decreased expression of AKR1C3 mRNA CTD PMID:28235592 NCBI chr13:4,182,614...4,200,645
Ensembl chr13:4,182,614...4,200,653
JBrowse link
G Akt1 thymoma viral proto-oncogene 1 multiple interactions ISO Colforsin inhibits the reaction [Oxidopamine results in decreased phosphorylation of AKT1 protein] CTD PMID:16339297 NCBI chr12:112,620,260...112,641,266
Ensembl chr12:112,620,255...112,641,318
JBrowse link
G Akt2 thymoma viral proto-oncogene 2 multiple interactions ISO Colforsin inhibits the reaction [Oxidopamine results in decreased phosphorylation of AKT2 protein] CTD PMID:16339297 NCBI chr 7:27,290,977...27,340,251
Ensembl chr 7:27,290,977...27,340,251
JBrowse link
G Akt3 thymoma viral proto-oncogene 3 multiple interactions ISO Colforsin inhibits the reaction [Oxidopamine results in decreased phosphorylation of AKT3 protein] CTD PMID:16339297 NCBI chr 1:176,847,642...177,091,688
Ensembl chr 1:176,847,639...177,085,769
JBrowse link
G Alb albumin multiple interactions ISO Colforsin inhibits the reaction [Carbon Tetrachloride results in decreased expression of ALB protein] CTD PMID:27590029 NCBI chr 5:90,608,729...90,624,461
Ensembl chr 5:90,608,756...90,624,461
JBrowse link
G Alpi alkaline phosphatase, intestinal multiple interactions ISO Colforsin inhibits the reaction [Methotrexate results in increased activity of ALPI protein] CTD PMID:16598758 NCBI chr 1:87,025,724...87,029,328
Ensembl chr 1:87,025,724...87,029,328
JBrowse link
G Aoc1 amine oxidase, copper-containing 1 increases activity ISO Colforsin results in increased activity of AOC1 protein CTD PMID:2860926 NCBI chr 6:48,872,189...48,886,122
Ensembl chr 6:48,849,830...48,886,122
JBrowse link
G Appbp2 amyloid beta precursor protein binding protein 2 decreases expression ISO Colforsin results in decreased expression of APPBP2 mRNA CTD PMID:16751804 NCBI chr11:85,082,134...85,125,946
Ensembl chr11:85,078,088...85,125,956
JBrowse link
G Ar androgen receptor multiple interactions
increases expression
ISO AR protein affects the reaction [Colforsin results in decreased expression of SESN1 protein]; AR protein promotes the reaction [Colforsin results in increased expression of HMGCR protein]; AR protein promotes the reaction [Colforsin results in increased expression of INSIG1 protein]; AR protein promotes the reaction [Colforsin results in increased expression of KLK2 protein]; AR protein promotes the reaction [Colforsin results in increased expression of KLK3 protein]; Colforsin promotes the reaction [Metribolone results in increased activity of AR protein]
Colforsin results in increased expression of AR protein
CTD PMID:16751804 PMID:17219378 NCBI chr  X:97,192,363...97,366,824
Ensembl chr  X:97,192,375...97,366,821
JBrowse link
G Areg amphiregulin increases expression
multiple interactions
ISO
EXP
Colforsin results in increased expression of AREG mRNA
N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Colforsin results in increased expression of AREG mRNA]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Colforsin results in increased expression of AREG protein]
CTD PMID:15284208 PMID:15313392 PMID:15474502 PMID:15967414 PMID:20378682 NCBI chr 5:91,287,458...91,296,291
Ensembl chr 5:91,287,458...91,296,291
JBrowse link
G Arrb1 arrestin, beta 1 multiple interactions ISO Colforsin inhibits the reaction [[carvedilol co-treated with ARRB1 protein] results in increased expression of MIR190A mRNA] CTD PMID:24334028 NCBI chr 7:99,184,356...99,255,979
Ensembl chr 7:99,184,673...99,255,978
JBrowse link
G Atxn3 ataxin 3 decreases expression ISO Colforsin results in decreased expression of ATXN3 mRNA CTD PMID:16751804 NCBI chr12:101,885,160...101,928,139
Ensembl chr12:101,885,160...101,924,505
JBrowse link
G Bcl2 B cell leukemia/lymphoma 2 multiple interactions ISO [S-(1,2-dichlorovinyl)cysteine co-treated with Colforsin] results in decreased expression of BCL2 mRNA; S-(1,2-dichlorovinyl)cysteine inhibits the reaction [Colforsin results in increased expression of BCL2 mRNA] CTD PMID:36336211 PMID:37544576 NCBI chr 1:106,465,906...106,642,020
Ensembl chr 1:106,465,908...106,642,004
JBrowse link
G Bdnf brain derived neurotrophic factor multiple interactions
increases expression
ISO
EXP
1-bromopropane inhibits the reaction [Colforsin results in increased expression of BDNF mRNA]; 1-bromopropane inhibits the reaction [Colforsin results in increased expression of BDNF protein]
Colforsin inhibits the reaction [Caffeine results in decreased expression of BDNF mRNA]; Colforsin inhibits the reaction [Caffeine results in decreased expression of BDNF protein]
Colforsin results in increased expression of BDNF mRNA; Colforsin results in increased expression of BDNF protein
CTD PMID:19189864 PMID:35917217 NCBI chr 2:109,505,045...109,557,388
Ensembl chr 2:109,505,045...109,557,352
JBrowse link
G Bmal1 basic helix-loop-helix ARNT like 1 increases expression EXP Colforsin results in increased expression of BMAL1 mRNA CTD PMID:30524225 NCBI chr 7:112,777,820...112,913,333
Ensembl chr 7:112,806,672...112,913,333
JBrowse link
G Bmp6 bone morphogenetic protein 6 multiple interactions ISO BMP6 protein inhibits the reaction [Colforsin results in increased expression of CYP11A1 mRNA]; BMP6 protein inhibits the reaction [Colforsin results in increased expression of CYP19A1 mRNA]; BMP6 protein inhibits the reaction [Colforsin results in increased expression of HSD3B1 mRNA]; BMP6 protein inhibits the reaction [Colforsin results in increased expression of OXT mRNA]; BMP6 protein inhibits the reaction [Colforsin results in increased expression of STAR mRNA]; BMP6 protein inhibits the reaction [Colforsin results in increased secretion of Progesterone]; FST protein inhibits the reaction [BMP6 protein inhibits the reaction [Colforsin results in increased secretion of Progesterone]] CTD PMID:18936084 NCBI chr13:38,529,098...38,684,283
Ensembl chr13:38,529,083...38,684,278
JBrowse link
G C4a complement C4A (Rodgers blood group) multiple interactions ISO [Colforsin co-treated with Diethylhexyl Phthalate] affects the expression of C4A mRNA CTD PMID:35892601 NCBI chr17:35,028,069...35,042,436
Ensembl chr17:35,028,069...35,042,440
JBrowse link
G Cacna1g calcium channel, voltage-dependent, T type, alpha 1G subunit multiple interactions ISO Mibefradil inhibits the reaction [[Colforsin co-treated with 1-Methyl-3-isobutylxanthine] results in increased activity of CACNA1G protein]; Nickel inhibits the reaction [[Colforsin co-treated with 1-Methyl-3-isobutylxanthine] results in increased activity of CACNA1G protein] CTD PMID:17110049 NCBI chr11:94,299,217...94,365,226
Ensembl chr11:94,299,217...94,365,024
JBrowse link
G Cacna1h calcium channel, voltage-dependent, T type, alpha 1H subunit multiple interactions ISO Mibefradil inhibits the reaction [[Colforsin co-treated with 1-Methyl-3-isobutylxanthine] results in increased activity of CACNA1H protein]; Nickel inhibits the reaction [[Colforsin co-treated with 1-Methyl-3-isobutylxanthine] results in increased activity of CACNA1H protein] CTD PMID:17110049 NCBI chr17:25,593,259...25,655,308
Ensembl chr17:25,593,259...25,652,759
JBrowse link
G Cacna1i calcium channel, voltage-dependent, alpha 1I subunit multiple interactions ISO Mibefradil inhibits the reaction [[Colforsin co-treated with 1-Methyl-3-isobutylxanthine] results in increased activity of CACNA1I protein]; Nickel inhibits the reaction [[Colforsin co-treated with 1-Methyl-3-isobutylxanthine] results in increased activity of CACNA1I protein] CTD PMID:17110049 NCBI chr15:80,171,439...80,282,493
Ensembl chr15:80,171,439...80,282,480
JBrowse link
G Calcrl calcitonin receptor-like multiple interactions ISO Colforsin inhibits the reaction [EDN1 protein results in increased expression of CALCRL mRNA] CTD PMID:25194819 NCBI chr 2:84,160,970...84,255,786
Ensembl chr 2:84,160,970...84,255,755
JBrowse link
G Camkk2 calcium/calmodulin-dependent protein kinase kinase 2, beta increases expression ISO Colforsin results in increased expression of CAMKK2 mRNA CTD PMID:16751804 NCBI chr 5:122,856,064...122,918,295
Ensembl chr 5:122,869,233...122,917,472
JBrowse link
G Cask calcium/calmodulin dependent serine protein kinase increases phosphorylation
multiple interactions
ISO Colforsin results in increased phosphorylation of CASK protein
Colforsin promotes the reaction [CASK protein modified form binds to TBR1 protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Colforsin results in increased phosphorylation of CASK protein]
CTD PMID:20067577 NCBI chr  X:13,383,319...13,713,020
Ensembl chr  X:13,383,319...13,717,606
JBrowse link
G Casp1 caspase 1 increases activity ISO Colforsin results in increased activity of CASP1 mRNA; Colforsin results in increased activity of CASP1 protein CTD PMID:21832250 NCBI chr 9:5,298,517...5,307,281
Ensembl chr 9:5,298,508...5,307,290
JBrowse link
G Casp3 caspase 3 increases activity
multiple interactions
ISO
EXP
Colforsin results in increased activity of CASP3 protein
Colforsin inhibits the reaction [Puromycin Aminonucleoside results in increased activity of CASP3 protein]
KT 5720 inhibits the reaction [Colforsin results in increased activity of CASP3 protein]
Colforsin inhibits the reaction [Cisplatin results in increased cleavage of and results in increased activity of CASP3 protein]
CTD PMID:16396944 PMID:20131233 PMID:21745194 PMID:31278978 NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724
JBrowse link
G Cat catalase multiple interactions ISO Colforsin inhibits the reaction [mancozeb results in decreased activity of CAT protein] CTD PMID:29283200 NCBI chr 2:103,284,249...103,315,498
Ensembl chr 2:103,284,194...103,315,505
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 multiple interactions EXP Colforsin inhibits the reaction [Reactive Oxygen Species results in increased expression of CCL5 mRNA]; Colforsin inhibits the reaction [TNF protein results in increased expression of CCL5 mRNA] CTD PMID:10495789 NCBI chr11:83,416,604...83,421,344
Ensembl chr11:83,416,604...83,421,344
JBrowse link
G Cd55 CD55 molecule, decay accelerating factor for complement multiple interactions
increases expression
ISO 3',4'-dimethoxy-alpha-naphthoflavone inhibits the reaction [Colforsin results in increased expression of CD55 mRNA] CTD PMID:22553215 NCBI chr 1:130,357,526...130,390,513
Ensembl chr 1:130,366,764...130,390,481
JBrowse link
G Cdc6 cell division cycle 6 increases expression ISO Colforsin results in increased expression of CDC6 mRNA CTD PMID:16751804 NCBI chr11:98,798,627...98,814,768
Ensembl chr11:98,798,627...98,814,766
JBrowse link
G Cdh1 cadherin 1 affects activity
decreases expression
increases expression
ISO Colforsin affects the activity of CDH1 protein
Colforsin results in decreased expression of CDH1 protein
Colforsin results in increased expression of CDH1 protein
CTD PMID:10413674 PMID:30983542 PMID:38301883 NCBI chr 8:107,329,982...107,396,879
Ensembl chr 8:107,329,983...107,396,878
JBrowse link
G Cdrt4 CMT1A duplicated region transcript 4 multiple interactions ISO [Colforsin co-treated with Diethylhexyl Phthalate] affects the expression of CDRT4 mRNA CTD PMID:35892601 NCBI chr11:62,842,019...62,883,921
Ensembl chr11:62,842,019...62,883,921
JBrowse link
G Cebpa CCAAT/enhancer binding protein alpha multiple interactions
increases expression
EXP
ISO
Colforsin inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CEBPA mRNA]
Colforsin inhibits the reaction [mono-(2-ethylhexyl)phthalate results in decreased expression of CEBPA protein]
Colforsin results in increased expression of CEBPA protein
CTD PMID:17407152 PMID:21832167 NCBI chr 7:34,818,718...34,821,353
Ensembl chr 7:34,818,718...34,821,353
JBrowse link
G Cebpb CCAAT/enhancer binding protein beta increases expression
multiple interactions
EXP
ISO
Colforsin results in increased expression of CEBPB mRNA
[Atrazine co-treated with Colforsin] results in increased expression of CEBPB protein
CTD PMID:14684744 PMID:25253736 NCBI chr 2:167,530,835...167,532,352
Ensembl chr 2:167,530,835...167,532,338
JBrowse link
G Cftr cystic fibrosis transmembrane conductance regulator affects localization
multiple interactions
increases activity
ISO
EXP
Colforsin affects the localization of CFTR protein
[Colforsin co-treated with Genistein] results in increased activity of CFTR protein; AICA ribonucleotide inhibits the reaction [Colforsin results in increased activity of CFTR protein]
[1-Methyl-3-isobutylxanthine co-treated with Colforsin] results in increased activity of CFTR protein; Colforsin promotes the reaction [Nimodipine results in increased activity of CFTR protein]
3-((3-trifluoromethyl)phenyl)-5-((3-carboxyphenyl)methylene)-2-thioxo-4-thiazolidinone inhibits the reaction [[[Colforsin co-treated with Genistein] results in increased activity of CFTR protein] which results in increased transport of Iodides]; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid inhibits the reaction [Colforsin results in increased activity of CFTR protein]; 5-butyl-6-hydroxy-10-chlorobenzo(c)quinolizinium chloride inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]; 5-butyl-7-chloro-6-hydroxybenzo(c)quinolizinium inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]; 6-hydroxy-10-chlorobenzo(c)quinolizinium inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]; [1-Methyl-3-isobutylxanthine co-treated with Colforsin] results in increased activity of CFTR protein; [1-Methyl-3-isobutylxanthine co-treated with Colforsin] results in increased activity of CFTR protein mutant form; [5-butyl-6-hydroxy-10-chlorobenzo(c)quinolizinium chloride co-treated with Colforsin] results in increased activity of CFTR protein mutant form; [[Colforsin co-treated with Genistein] results in increased activity of CFTR protein] which results in increased transport of Iodides; [Colforsin co-treated with 1-Methyl-3-isobutylxanthine] results in increased activity of CFTR protein; [Colforsin co-treated with Genistein] results in increased activity of CFTR protein; [Colforsin co-treated with lumacaftor] results in increased activity of CFTR protein mutant form; [Colforsin co-treated with NS 004] results in increased activity of CFTR protein mutant form; [ivacaftor co-treated with Colforsin co-treated with lumacaftor] results in increased activity of CFTR protein mutant form; [ivacaftor co-treated with Colforsin] results in increased activity of CFTR protein; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [5-butyl-7-chloro-6-hydroxybenzo(c)quinolizinium inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [miglustat inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]]; Brefeldin A inhibits the reaction [5-butyl-7-chloro-6-hydroxybenzo(c)quinolizinium inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]]; Brefeldin A inhibits the reaction [miglustat inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]]; CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]; Colforsin binds to and results in decreased activity of CFTR protein; Colforsin promotes the reaction [CFTR protein affects the export of Chlorides]; Colforsin promotes the reaction [Nimodipine results in increased activity of CFTR protein]; Colforsin results in increased phosphorylation of and results in increased activity of CFTR protein; fenamic acid inhibits the reaction [[[Colforsin co-treated with Genistein] results in increased activity of CFTR protein] which results in increased transport of Iodides]; fenamic acid inhibits the reaction [Colforsin results in increased activity of CFTR protein]; geldanamycin promotes the reaction [5-butyl-7-chloro-6-hydroxybenzo(c)quinolizinium inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]]; geldanamycin promotes the reaction [miglustat inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]]; Glyburide inhibits the reaction [[[Colforsin co-treated with Genistein] results in increased activity of CFTR protein] which results in increased transport of Iodides]; Glyburide inhibits the reaction [Colforsin results in increased activity of CFTR protein]; miglustat inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Colforsin results in increased activity of CFTR protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Colforsin results in increased phosphorylation of CFTR protein]; Ozone inhibits the reaction [Colforsin results in increased activity of CFTR protein]; Thapsigargin promotes the reaction [5-butyl-7-chloro-6-hydroxybenzo(c)quinolizinium inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]]; Thapsigargin promotes the reaction [miglustat inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]]; VRT 532 analog promotes the reaction [Colforsin results in increased activity of CFTR protein mutant form]; VRT 532 promotes the reaction [Colforsin results in increased activity of CFTR protein mutant form]
Colforsin analog results in increased activity of CFTR protein mutant form; Colforsin results in increased activity of CFTR protein; Colforsin results in increased activity of CFTR protein mutant form
CTD PMID:12519745 PMID:12914781 PMID:14502435 PMID:14967738 PMID:15163550 More... NCBI chr 6:18,170,686...18,322,769
Ensembl chr 6:18,170,686...18,322,767
JBrowse link
G Cga glycoprotein hormones, alpha subunit increases secretion
increases expression
multiple interactions
ISO
EXP
Colforsin results in increased secretion of CGA protein
Colforsin results in increased expression of CGA protein
Colforsin results in increased expression of CGA mRNA
Colforsin promotes the reaction [CGA protein results in increased abundance of Cyclic AMP]; perfluorobutanesulfonic acid inhibits the reaction [Colforsin results in increased expression of CGA protein]; perfluorooctane sulfonic acid inhibits the reaction [Colforsin results in increased expression of CGA protein]
Colforsin inhibits the reaction [ESR2 gene mutant form inhibits the reaction [CGA protein results in increased abundance of Cyclic AMP]]
CTD PMID:8404651 PMID:16503475 PMID:20378682 PMID:33144174 NCBI chr 4:34,893,779...34,907,374
Ensembl chr 4:34,893,779...34,907,370
JBrowse link
G Cidec cell death-inducing DFFA-like effector c increases expression EXP Colforsin results in increased expression of CIDEC protein CTD PMID:21097823 NCBI chr 6:113,401,595...113,412,721
Ensembl chr 6:113,401,595...113,412,721
JBrowse link
G Cnr1 cannabinoid receptor 1 multiple interactions
affects response to substance
increases activity
ISO (1-(2-morpholin-4-yl-ethyl)-1H-indol-3-yl)-(2,2,3,3-tetramethylcyclopropyl)methanone inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; (1-pentyl-1H-indol-3-yl)(2,2,3,3-tetramethylcyclopropyl)methanone inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; (4-ethyl-1-naphthalenyl)(1-(5-fluoropentyl)-1H-indol-3-yl)methanone inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; 1-(2-cyclohexylethyl)-3-(2-methoxyphenylacetyl)indole inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; 1-(5-fluoropentyl)-3-(4-methyl-1-naphthoyl)indole analog inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; 1-(5-fluoropentyl)-3-(4-methyl-1-naphthoyl)indole inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; 1-(cyclohexylmethyl)-1H-indole-3-carboxylic acid 8-quinolinyl ester inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; 1-pentyfluoro-1H-indole-3-carboxylic acid 8-quinolinyl ester inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; 1-pentyl-1H-indole-3-carboxylic acid 8-quinolinyl ester inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; 1-pentyl-3-(1-naphthoyl)indole analog inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; 2-(4-methoxyphenyl)-1-(1-pentyl-indol-3-yl)methanone inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; 3-((adamantan-1-yl)carbonyl)-1-pentylindole analog inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; 3-((adamantan-1-yl)carbonyl)-1-pentylindole inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; 3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol inhibits the reaction [Colforsin results in increased activity of CNR1 protein]; [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]; [Dronabinol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]; [Medroxyprogesterone Acetate co-treated with Estradiol co-treated with Colforsin] results in increased expression of CNR1 mRNA; AM 6527 analog inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; AM 6527 inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; CNR1 protein inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]; delta(9)-tetrahydrocannabinolic acid inhibits the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol inhibits the reaction [Colforsin results in increased activity of CNR1 protein]]; delta(9)-tetrahydrocannabinolic acid inhibits the reaction [Colforsin results in increased activity of CNR1 protein]; Dronabinol inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; Dronabinol inhibits the reaction [Colforsin results in increased activity of CNR1 protein]; FDU-PB-22 inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; FUB-PB-22 compound inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; Indazoles analog inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; Indoles analog inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; N-(1-adamantyl)-1-(5-fluoropentyl)-1H-indazole-3-carboxamide inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; N-(1-adamantyl)-1-pentylindazole-3-carboxamide analog inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; N-(adamantan-1-yl)-1-(5-fluoropentyl)-1H-indole-3-carboxamide inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; N-(adamtan-1-yl)-1-pentyl-1H-indole-3-carboxamide analog inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; N-(adamtan-1-yl)-1-pentyl-1H-indole-3-carboxamide inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; N-1-naphthalenyl-1-pentyl-1H-indazole-3-carboxamide analog inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; N-1-naphthalenyl-1-pentyl-1H-indazole-3-carboxamide inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; napht-1-yl 1-(5-fluoropentyl)-1H-indole-3-carboxylate inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; THJ-2201 inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; XLR-11 analog inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; XLR-11 inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]
CNR1 protein affects the susceptibility to Colforsin
CTD PMID:27429655 PMID:27527584 PMID:28861508 PMID:31154070 NCBI chr 4:33,923,171...33,948,831
Ensembl chr 4:33,924,593...33,948,831
JBrowse link
G Cnr2 cannabinoid receptor 2 multiple interactions
increases activity
affects response to substance
ISO
EXP
(1-(2-morpholin-4-yl-ethyl)-1H-indol-3-yl)-(2,2,3,3-tetramethylcyclopropyl)methanone inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; (1-pentyl-1H-indol-3-yl)(2,2,3,3-tetramethylcyclopropyl)methanone inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; (4-ethyl-1-naphthalenyl)(1-(5-fluoropentyl)-1H-indol-3-yl)methanone inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; 1-(2-cyclohexylethyl)-3-(2-methoxyphenylacetyl)indole inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; 1-(5-fluoropentyl)-3-(4-methyl-1-naphthoyl)indole analog inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; 1-(5-fluoropentyl)-3-(4-methyl-1-naphthoyl)indole inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; 1-(cyclohexylmethyl)-1H-indole-3-carboxylic acid 8-quinolinyl ester inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; 1-pentyfluoro-1H-indole-3-carboxylic acid 8-quinolinyl ester inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; 1-pentyl-1H-indole-3-carboxylic acid 8-quinolinyl ester inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; 1-pentyl-3-(1-naphthoyl)indole analog inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; 2-(4-methoxyphenyl)-1-(1-pentyl-indol-3-yl)methanone inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; 3-((adamantan-1-yl)carbonyl)-1-pentylindole analog inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; 3-((adamantan-1-yl)carbonyl)-1-pentylindole inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; 3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol inhibits the reaction [Colforsin results in increased activity of CNR2 protein]; [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased abundance of Cyclic AMP]; [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]; [Dronabinol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]; [Medroxyprogesterone Acetate co-treated with Estradiol co-treated with Colforsin] results in increased expression of CNR2 mRNA; [virodhamine binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased abundance of Cyclic AMP]; AM 6527 analog inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; AM 6527 inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; CNR2 protein inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]; Dronabinol inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; Dronabinol inhibits the reaction [Colforsin results in increased activity of CNR2 protein]; FDU-PB-22 inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; FUB-PB-22 compound inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; Indazoles analog inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; Indoles analog inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; N-(1-adamantyl)-1-(5-fluoropentyl)-1H-indazole-3-carboxamide inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; N-(1-adamantyl)-1-pentylindazole-3-carboxamide analog inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; N-(adamantan-1-yl)-1-(5-fluoropentyl)-1H-indole-3-carboxamide inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; N-(adamtan-1-yl)-1-pentyl-1H-indole-3-carboxamide analog inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; N-(adamtan-1-yl)-1-pentyl-1H-indole-3-carboxamide inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; N-1-naphthalenyl-1-pentyl-1H-indazole-3-carboxamide analog inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; N-1-naphthalenyl-1-pentyl-1H-indazole-3-carboxamide inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; napht-1-yl 1-(5-fluoropentyl)-1H-indole-3-carboxylate inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; Pertussis Toxin inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased abundance of Cyclic AMP]]; Pertussis Toxin inhibits the reaction [[virodhamine binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased abundance of Cyclic AMP]]; SR 144528 inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased abundance of Cyclic AMP]]; SR 144528 inhibits the reaction [[virodhamine binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased abundance of Cyclic AMP]]; THJ-2201 inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; XLR-11 analog inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; XLR-11 inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]
CNR2 protein affects the susceptibility to Colforsin
CTD PMID:17558435 PMID:27429655 PMID:27527584 PMID:28861508 PMID:30504240 More... NCBI chr 4:135,622,500...135,647,530
Ensembl chr 4:135,622,705...135,647,518
JBrowse link
G Creb1 cAMP responsive element binding protein 1 increases activity
increases expression
increases phosphorylation
multiple interactions
EXP
ISO
Colforsin results in increased activity of CREB1 protein
Colforsin results in increased expression of CREB1 mRNA; Colforsin results in increased expression of CREB1 protein modified form
Colforsin results in increased phosphorylation of CREB1 protein
3-(3-chloro-4-hydroxyphenylamino)-4-(4-nitrophenyl)-1H-pyrrole-2,5-dione inhibits the reaction [Resveratrol inhibits the reaction [Colforsin results in increased phosphorylation of CREB1 protein]]; Colforsin inhibits the reaction [Caffeine results in decreased expression of CREB1 mRNA]; Colforsin inhibits the reaction [Carbon Tetrachloride results in decreased expression of CREB1 protein modified form]; Colforsin promotes the reaction [CREB1 protein binds to POU1F1 promoter]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Colforsin results in increased phosphorylation of CREB1 protein]; Okadaic Acid inhibits the reaction [Resveratrol inhibits the reaction [Colforsin results in increased phosphorylation of CREB1 protein]]; Resveratrol inhibits the reaction [Colforsin promotes the reaction [CREB1 protein binds to POU1F1 promoter]]; Resveratrol inhibits the reaction [Colforsin results in increased phosphorylation of CREB1 protein]; SIRT1 mutant form inhibits the reaction [Resveratrol inhibits the reaction [Colforsin results in increased phosphorylation of CREB1 protein]]; SIRT1 protein inhibits the reaction [Colforsin results in increased phosphorylation of CREB1 protein]; SIRT1 protein mutant form inhibits the reaction [Colforsin results in increased phosphorylation of CREB1 protein]
AKAP13 protein modified form inhibits the reaction [Colforsin results in increased phosphorylation of CREB1 protein]; anandamide inhibits the reaction [Colforsin results in increased phosphorylation of CREB1 protein]; Colforsin inhibits the reaction [anandamide inhibits the reaction [CREB1 protein modified form binds to ABCG2 promoter]]; Colforsin results in increased phosphorylation of and results in increased activity of CREB1 protein
[Colforsin co-treated with 1-Methyl-3-isobutylxanthine] results in increased phosphorylation of CREB1 protein; alisol B inhibits the reaction [[Colforsin co-treated with 1-Methyl-3-isobutylxanthine] results in increased phosphorylation of CREB1 protein]; oxophenylarsine inhibits the reaction [Colforsin results in increased activity of CREB1 protein]; oxophenylarsine inhibits the reaction [Colforsin results in increased phosphorylation of CREB1 protein]; RTKI cpd inhibits the reaction [Colforsin results in increased phosphorylation of CREB1 protein]
CTD PMID:10908723 PMID:11113530 PMID:15522277 PMID:17141199 PMID:17322281 More... NCBI chr 1:64,571,963...64,643,707
Ensembl chr 1:64,571,804...64,643,707
JBrowse link
G Crebbp CREB binding protein multiple interactions ISO Colforsin promotes the reaction [GCM1 protein binds to CREBBP protein]; CREBBP protein affects the reaction [Colforsin results in increased activity of GCM1 protein] CTD PMID:16166624 NCBI chr16:3,899,198...4,031,864
Ensembl chr16:3,899,192...4,031,861
JBrowse link
G Crem cAMP responsive element modulator increases expression ISO Colforsin results in increased expression of CREM mRNA; Colforsin results in increased expression of CREM mRNA alternative form; Colforsin results in increased expression of CREM protein CTD PMID:8810303 PMID:12791704 NCBI chr18:3,263,181...3,337,688
Ensembl chr18:3,266,048...3,337,748
JBrowse link
G Crh corticotropin releasing hormone multiple interactions
increases secretion
ISO CRH protein inhibits the reaction [[Colforsin co-treated with CGB3 protein] results in increased chemical synthesis of Cyclic AMP]; CRH protein inhibits the reaction [[Colforsin co-treated with CGB3 protein] results in increased chemical synthesis of Testosterone]; CRH protein inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]; CRH protein inhibits the reaction [Colforsin results in increased chemical synthesis of Testosterone]
[perfluorooctane sulfonic acid co-treated with Colforsin] results in increased expression of CRH mRNA
Colforsin results in increased secretion of CRH protein
CTD PMID:2153673 PMID:33144174 NCBI chr 3:19,747,565...19,749,560
Ensembl chr 3:19,747,565...19,749,560
JBrowse link
G Crls1 cardiolipin synthase 1 increases expression ISO Colforsin results in increased expression of CRLS1 mRNA CTD PMID:16751804 NCBI chr 2:132,688,557...132,708,706
Ensembl chr 2:132,688,586...132,708,705
JBrowse link
G Cryab crystallin, alpha B multiple interactions ISO Colforsin inhibits the reaction [arsenite results in increased expression of CRYAB protein] CTD PMID:8769853 NCBI chr 9:50,657,251...50,667,936
Ensembl chr 9:50,662,625...50,667,936
JBrowse link
G Cxcl15 C-X-C motif chemokine ligand 15 multiple interactions EXP
ISO
Colforsin promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CXCL15 mRNA]
[Colforsin results in increased activity of AHR protein] which results in increased expression of CXCL8 mRNA; [Colforsin results in increased activity of AHR protein] which results in increased expression of CXCL8 protein; [Colforsin results in increased activity of AHR protein] which results in increased secretion of CXCL8 protein; [nickel sulfate co-treated with Colforsin] results in increased secretion of CXCL8 protein; Colforsin promotes the reaction [[AHR protein binds to RELB protein] which binds to CXCL8 promoter]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Colforsin promotes the reaction [[AHR protein binds to RELB protein] which binds to CXCL8 promoter]]
CTD PMID:17823304 PMID:19063610 PMID:23526216 NCBI chr 5:90,942,393...90,950,926
Ensembl chr 5:90,942,393...90,950,926
JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 affects expression
multiple interactions
increases expression
ISO
EXP
Colforsin affects the expression of CYP11A1 mRNA
[Colforsin co-treated with Zearalenone] results in increased expression of CYP11A1 mRNA
Colforsin results in increased expression of CYP11A1 mRNA
[Colforsin co-treated with triptolide] results in decreased expression of CYP11A1 mRNA; Aminoglutethimide inhibits the reaction [Colforsin results in increased expression of CYP11A1 mRNA]; BMP6 protein inhibits the reaction [Colforsin results in increased expression of CYP11A1 mRNA]; Hexachlorocyclohexane inhibits the reaction [Colforsin results in increased expression of CYP11A1 mRNA]; Metyrapone inhibits the reaction [Colforsin results in increased expression of CYP11A1 mRNA]; Valproic Acid affects the reaction [Colforsin affects the expression of CYP11A1 mRNA]
[Atrazine co-treated with Colforsin] results in increased expression of CYP11A1 mRNA; RARRES2 protein inhibits the reaction [Colforsin results in increased expression of CYP11A1 protein]
CTD PMID:14691014 PMID:16935330 PMID:17080404 PMID:18936084 PMID:20726872 More... NCBI chr 9:57,905,307...57,934,314
Ensembl chr 9:57,913,694...57,934,306
JBrowse link
G Cyp11b1 cytochrome P450, family 11, subfamily b, polypeptide 1 increases activity
multiple interactions
EXP Colforsin results in increased activity of CYP11B1 protein
1-chloro-4-(2,2-dichloro-1-(4-chlorophenyl)ethenyl)-3-(methylsulfonyl)benzene inhibits the reaction [Colforsin results in increased activity of CYP11B1 protein]; 2,2-(2-chlorophenyl-4'-chlorophenyl)-1,1-dichloroethene inhibits the reaction [Colforsin results in increased activity of CYP11B1 protein]; Etomidate inhibits the reaction [Colforsin results in increased activity of CYP11B1 protein]
CTD PMID:18651133 NCBI chr15:74,706,741...74,713,492
Ensembl chr15:74,705,974...74,713,492
JBrowse link
G Cyp11b2 cytochrome P450, family 11, subfamily b, polypeptide 2 increases expression
multiple interactions
ISO Colforsin results in increased expression of CYP11B2 mRNA
[1-chloro-4-(2,2-dichloro-1-(4-chlorophenyl)ethenyl)-3-(methylsulfonyl)benzene co-treated with Colforsin] affects the expression of CYP11B2 mRNA; [Colforsin co-treated with triptolide] results in decreased expression of CYP11B2 mRNA; Hexachlorocyclohexane inhibits the reaction [Colforsin results in increased expression of CYP11B2 mRNA]; Ketoconazole promotes the reaction [Colforsin results in increased expression of CYP11B2 mRNA]
CTD PMID:16935330 PMID:17080404 PMID:19164467 PMID:19900470 PMID:21256172 More... NCBI chr15:74,722,467...74,728,080
Ensembl chr15:74,722,467...74,728,167
JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 increases expression
multiple interactions
EXP
ISO
Colforsin results in increased expression of CYP17A1 mRNA
[Colforsin co-treated with triptolide] results in decreased expression of CYP17A1 mRNA; Apigenin inhibits the reaction [Colforsin results in increased expression of CYP17A1 mRNA]; Hexachlorocyclohexane inhibits the reaction [Colforsin results in increased expression of CYP17A1 mRNA]; Ketoconazole inhibits the reaction [Colforsin results in increased expression of CYP17A1 mRNA]; Metyrapone inhibits the reaction [Colforsin results in increased expression of CYP17A1 mRNA]; TGFB1 protein inhibits the reaction [Colforsin results in increased expression of CYP17A1 mRNA]; Valproic Acid inhibits the reaction [Colforsin results in increased expression of CYP17A1 mRNA]
CTD PMID:15625562 PMID:15886251 PMID:16935330 PMID:17080404 PMID:20726872 More... NCBI chr19:46,655,604...46,661,439
Ensembl chr19:46,655,604...46,661,611
JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 increases activity
increases expression
multiple interactions
ISO
EXP
Colforsin results in increased activity of CYP19A1 protein
Colforsin results in increased expression of CYP19A1 mRNA
1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [Colforsin results in increased expression of CYP19A1 mRNA]; [Colforsin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CYP19A1 mRNA; [Colforsin results in increased activity of CYP19A1 protein] which results in increased abundance of Estradiol; [Colforsin results in increased activity of CYP19A1 protein] which results in increased abundance of Testosterone; Alitretinoin inhibits the reaction [NR5A2 protein promotes the reaction [[Colforsin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CYP19A1 mRNA]]; Aminoglutethimide inhibits the reaction [Colforsin results in increased expression of CYP19A1 mRNA]; Atrazine inhibits the reaction [Colforsin results in increased expression of CYP19A1 mRNA]; BMP6 protein inhibits the reaction [Colforsin results in increased expression of CYP19A1 mRNA]; Hexachlorocyclohexane inhibits the reaction [Colforsin results in increased expression of CYP19A1 mRNA]; mono-(2-ethylhexyl)phthalate inhibits the reaction [Colforsin results in increased expression of CYP19A1 mRNA]; NR4A1 protein inhibits the reaction [Colforsin results in increased expression of CYP19A1 mRNA]; NR4A2 protein inhibits the reaction [Colforsin results in increased expression of CYP19A1 mRNA]; NR4A3 protein inhibits the reaction [Colforsin results in increased expression of CYP19A1 mRNA]; NR5A2 protein promotes the reaction [[Colforsin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CYP19A1 mRNA]; Valproic Acid inhibits the reaction [Colforsin results in increased activity of CYP19A1 protein]; Valproic Acid inhibits the reaction [Colforsin results in increased expression of CYP19A1 mRNA]; ZNF461 protein inhibits the reaction [Colforsin results in increased expression of CYP19A1 mRNA]
RARRES2 protein inhibits the reaction [Colforsin results in increased expression of CYP19A1 protein]
Colforsin results in increased expression of CYP19A1 mRNA; Colforsin results in increased expression of CYP19A1 protein
CTD PMID:14691014 PMID:16357189 PMID:16935330 PMID:16996190 PMID:17080404 More... NCBI chr 9:54,073,221...54,175,448
Ensembl chr 9:54,073,221...54,175,394
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions
affects expression
ISO
EXP
Colforsin inhibits the reaction [Lipopolysaccharides results in decreased activity of CYP1A1 protein]
Valproic Acid affects the reaction [Colforsin affects the expression of CYP1A1 mRNA]
Colforsin affects the reaction [Benzo(a)pyrene results in increased expression of CYP1A1 mRNA]
CTD PMID:1849469 PMID:15710352 PMID:20726872 NCBI chr 9:57,595,211...57,611,107
Ensembl chr 9:57,595,211...57,611,107
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions EXP
ISO
Colforsin affects the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 mRNA]
Colforsin inhibits the reaction [Lipopolysaccharides results in decreased activity of CYP1A2 protein]
CTD PMID:1849469 PMID:15710352 NCBI chr 9:57,584,220...57,590,938
Ensembl chr 9:57,584,220...57,590,986
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 increases expression ISO Colforsin results in increased expression of CYP1B1 mRNA; Colforsin results in increased expression of CYP1B1 protein CTD PMID:7588239 NCBI chr17:80,014,369...80,022,490
Ensembl chr17:80,008,966...80,022,490
JBrowse link
G Cyp21a1 cytochrome P450, family 21, subfamily a, polypeptide 1 multiple interactions
increases expression
ISO [Colforsin co-treated with Ketoconazole] results in decreased expression of CYP21A2 mRNA; [Colforsin co-treated with triptolide] results in decreased expression of CYP21A2 mRNA; Apigenin inhibits the reaction [Colforsin results in increased expression of CYP21A2 mRNA]; daidzein inhibits the reaction [Colforsin results in increased expression of CYP21A2 mRNA]; Valproic Acid inhibits the reaction [Colforsin results in increased expression of CYP21A2 mRNA] CTD PMID:16935330 PMID:20726872 PMID:21256172 PMID:22446829 PMID:23370353 More... NCBI chr17:35,020,322...35,023,400
Ensembl chr17:35,020,322...35,023,535
JBrowse link
G Cyp2a5 cytochrome P450, family 2, subfamily a, polypeptide 5 increases expression EXP Colforsin results in increased expression of CYP2A5 mRNA CTD PMID:11162586 NCBI chr 7:26,534,764...26,542,689
Ensembl chr 7:26,534,730...26,542,973
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions ISO [S-(1,2-dichlorovinyl)cysteine co-treated with Colforsin] results in decreased expression of CYP2E1 mRNA CTD PMID:37544576 NCBI chr 7:140,343,732...140,354,903
Ensembl chr 7:140,343,652...140,354,900
JBrowse link
G Dbh dopamine beta hydroxylase multiple interactions
increases expression
ISO Colforsin inhibits the reaction [Atrazine results in decreased expression of DBH protein]; Colforsin inhibits the reaction [Simazine results in decreased expression of DBH protein]
Colforsin results in increased expression of DBH protein
CTD PMID:14550852 NCBI chr 2:27,055,519...27,073,216
Ensembl chr 2:27,055,245...27,073,212
JBrowse link
G Dct dopachrome tautomerase increases expression ISO Colforsin results in increased expression of DCT mRNA; Colforsin results in increased expression of DCT protein CTD PMID:17460731 PMID:28601556 NCBI chr14:118,250,202...118,289,658
Ensembl chr14:118,250,202...118,289,656
JBrowse link
G Dio2 deiodinase, iodothyronine, type II increases activity
multiple interactions
increases expression
EXP
ISO
Colforsin results in increased activity of DIO2 protein
Buthionine Sulfoximine inhibits the reaction [Colforsin results in increased activity of DIO2 protein]; Hydrogen Peroxide inhibits the reaction [Colforsin results in increased activity of DIO2 protein]; Hydrogen Peroxide inhibits the reaction [Colforsin results in increased expression of DIO2 mRNA]; Sodium Selenite inhibits the reaction [Hydrogen Peroxide inhibits the reaction [Colforsin results in increased activity of DIO2 protein]]; U 0126 inhibits the reaction [Hydrogen Peroxide inhibits the reaction [Colforsin results in increased activity of DIO2 protein]]; U 0126 inhibits the reaction [Hydrogen Peroxide inhibits the reaction [Colforsin results in increased expression of DIO2 mRNA]]
CTD PMID:18420745 PMID:19036883 NCBI chr12:90,691,326...90,705,812
Ensembl chr12:90,691,326...90,705,812
JBrowse link
G Dio3 deiodinase, iodothyronine type III multiple interactions ISO Colforsin promotes the reaction [Hydrogen Peroxide results in increased expression of DIO3 mRNA] CTD PMID:18420745 NCBI chr12:110,245,664...110,247,531
Ensembl chr12:110,245,502...110,247,531
JBrowse link
G Dnm1l dynamin 1-like decreases expression
multiple interactions
ISO Colforsin results in decreased expression of DNM1L protein
PINK1 protein affects the reaction [Colforsin results in decreased expression of DNM1L protein]
CTD PMID:24792327 NCBI chr16:16,130,092...16,176,863
Ensembl chr16:16,130,094...16,176,823
JBrowse link
G Drd2 dopamine receptor D2 multiple interactions ISO [Quinpirole binds to and results in increased activity of DRD2 protein] inhibits the reaction [Colforsin results in increased abundance of Cyclic AMP]; epigallocatechin gallate inhibits the reaction [[Quinpirole binds to and results in increased activity of DRD2 protein] inhibits the reaction [Colforsin results in increased abundance of Cyclic AMP]] CTD PMID:17958328 NCBI chr 9:49,251,703...49,319,468
Ensembl chr 9:49,251,927...49,319,477
JBrowse link
G Dynll2 dynein light chain LC8-type 2 increases expression ISO Colforsin results in increased expression of DYNLL2 mRNA CTD PMID:16751804 NCBI chr11:87,870,351...87,892,746
Ensembl chr11:87,870,351...87,878,359
JBrowse link
G Edn1 endothelin 1 multiple interactions ISO Colforsin inhibits the reaction [EDN1 protein results in increased expression of CALCRL mRNA]; Colforsin inhibits the reaction [EDN1 protein results in increased expression of ICAM2 mRNA] CTD PMID:25194819 NCBI chr13:42,454,952...42,461,466
Ensembl chr13:42,454,952...42,461,466
JBrowse link
G Egf epidermal growth factor multiple interactions ISO [EGF co-treated with Colforsin co-treated with Rotenone] results in increased expression of HSPD1 mRNA; [EGF co-treated with Colforsin co-treated with Rotenone] results in increased expression of SOD1 mRNA; [EGF co-treated with Colforsin co-treated with Rotenone] results in increased expression of SOD1 protein; [EGF co-treated with Colforsin co-treated with Rotenone] results in increased expression of SOD2 mRNA; [EGF co-treated with Colforsin co-treated with Rotenone] results in increased expression of SOD2 protein; Acetylcysteine inhibits the reaction [[EGF co-treated with Colforsin co-treated with Rotenone] results in increased expression of HSPD1 mRNA]; Acetylcysteine inhibits the reaction [[EGF co-treated with Colforsin co-treated with Rotenone] results in increased expression of SOD1 mRNA]; Acetylcysteine inhibits the reaction [[EGF co-treated with Colforsin co-treated with Rotenone] results in increased expression of SOD1 protein]; Acetylcysteine inhibits the reaction [[EGF co-treated with Colforsin co-treated with Rotenone] results in increased expression of SOD2 mRNA]; Acetylcysteine inhibits the reaction [[EGF co-treated with Colforsin co-treated with Rotenone] results in increased expression of SOD2 protein] CTD PMID:32092105 NCBI chr 3:129,471,223...129,548,971
Ensembl chr 3:129,471,214...129,548,965
JBrowse link
G Egr1 early growth response 1 multiple interactions
decreases expression
ISO Colforsin inhibits the reaction [Ethanol results in increased expression of EGR1 mRNA]; Colforsin inhibits the reaction [Ethanol results in increased expression of EGR1 protein]; Ethanol inhibits the reaction [Colforsin results in decreased expression of EGR1 mRNA]; Ethanol inhibits the reaction [Colforsin results in decreased expression of EGR1 protein]
Colforsin results in decreased expression of EGR1 mRNA; Colforsin results in decreased expression of EGR1 protein
CTD PMID:29802914 NCBI chr18:34,994,260...34,998,009
Ensembl chr18:34,992,876...34,998,037
JBrowse link
G Eif2b5 eukaryotic translation initiation factor 2B, subunit 5 epsilon increases expression ISO Colforsin results in increased expression of EIF2B5 mRNA CTD PMID:16751804 NCBI chr16:20,317,544...20,328,073
Ensembl chr16:20,317,567...20,328,073
JBrowse link
G Eif5a2 eukaryotic translation initiation factor 5A2 decreases expression ISO Colforsin results in decreased expression of EIF5A2 mRNA CTD PMID:30983542 NCBI chr 3:28,835,426...28,852,995
Ensembl chr 3:28,835,425...28,852,995
JBrowse link
G Ephx1 epoxide hydrolase 1, microsomal affects expression
multiple interactions
ISO Colforsin affects the expression of EPHX1 mRNA
Valproic Acid affects the reaction [Colforsin affects the expression of EPHX1 mRNA]
CTD PMID:20726872 NCBI chr 1:180,817,121...180,845,134
Ensembl chr 1:180,803,775...180,848,469
JBrowse link
G Eps8 epidermal growth factor receptor pathway substrate 8 decreases expression ISO Colforsin results in decreased expression of EPS8 mRNA CTD PMID:15313392 PMID:15967414 NCBI chr 6:137,454,242...137,626,262
Ensembl chr 6:137,454,243...137,631,874
JBrowse link
G Ereg epiregulin increases expression ISO
EXP
Colforsin results in increased expression of EREG mRNA CTD PMID:15313392 PMID:15474502 PMID:15967414 PMID:20378682 NCBI chr 5:91,222,476...91,241,508
Ensembl chr 5:91,222,481...91,241,505
JBrowse link
G Esr1 estrogen receptor 1 (alpha) decreases expression ISO Colforsin results in decreased expression of ESR1 mRNA CTD PMID:31278978 NCBI chr10:4,561,989...4,955,633
Ensembl chr10:4,561,593...4,955,614
JBrowse link
G Esr2 estrogen receptor 2 (beta) multiple interactions
decreases expression
EXP
ISO
Colforsin inhibits the reaction [ESR2 gene mutant form inhibits the reaction [CGA protein results in increased abundance of Cyclic AMP]]
Colforsin results in decreased expression of ESR2 mRNA
CTD PMID:20378682 PMID:31278978 NCBI chr12:76,167,193...76,224,033
Ensembl chr12:76,167,193...76,224,033
JBrowse link
G Esrra estrogen related receptor, alpha increases expression ISO Colforsin results in increased expression of ESRRA mRNA; Colforsin results in increased expression of ESRRA protein CTD PMID:20351196 NCBI chr19:6,888,345...6,899,182
Ensembl chr19:6,888,345...6,899,208
JBrowse link
G Evi5 ecotropic viral integration site 5 increases expression ISO Colforsin results in increased expression of EVI5 mRNA CTD PMID:16751804 NCBI chr 5:107,892,661...108,022,973
Ensembl chr 5:107,892,661...108,022,973
JBrowse link
G F2 coagulation factor II multiple interactions ISO Colforsin inhibits the reaction [F2 protein results in increased uptake of Manganese] CTD PMID:2125206 NCBI chr 2:91,442,742...91,466,799
Ensembl chr 2:91,455,665...91,466,759
JBrowse link
G F2r coagulation factor II thrombin receptor multiple interactions EXP [C186 65 binds to and results in increased activity of F2R protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP] CTD PMID:22207716 NCBI chr13:95,738,288...95,754,974
Ensembl chr13:95,738,311...95,754,995
JBrowse link
G F2rl3 F2R like thrombin or trypsin receptor 3 multiple interactions EXP [GYPGKF-NH(2) binds to and results in increased activity of F2RL3 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP] CTD PMID:22207716 NCBI chr 8:73,488,287...73,490,526
Ensembl chr 8:73,488,508...73,490,502
JBrowse link
G Fads1 fatty acid desaturase 1 increases expression ISO Colforsin results in increased expression of FADS1 mRNA CTD PMID:16751804 NCBI chr19:10,160,245...10,174,238
Ensembl chr19:10,160,252...10,174,241
JBrowse link
G Fasn fatty acid synthase multiple interactions ISO [Colforsin co-treated with 6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime] results in increased expression of FASN mRNA; [Colforsin co-treated with Leflunomide] results in increased expression of FASN mRNA; [Colforsin co-treated with teriflunomide] results in increased expression of FASN mRNA CTD PMID:30364229 NCBI chr11:120,696,784...120,715,992
Ensembl chr11:120,696,672...120,715,373
JBrowse link
G Fdx1 ferredoxin 1 increases expression
multiple interactions
EXP Colforsin results in increased expression of FDX1 mRNA
ferulic acid analog promotes the reaction [Colforsin results in increased expression of FDX1 mRNA]
CTD PMID:36279966 NCBI chr 9:51,854,323...51,874,902
Ensembl chr 9:51,854,606...51,874,856
JBrowse link
G Fgf10 fibroblast growth factor 10 multiple interactions ISO Colforsin inhibits the reaction [FGF10 protein results in increased phosphorylation of MAPK1 protein]; Colforsin inhibits the reaction [FGF10 protein results in increased phosphorylation of MAPK3 protein] CTD PMID:12533312 PMID:14975937 NCBI chr13:118,851,199...118,928,651
Ensembl chr13:118,806,327...118,928,651
JBrowse link
G Fgf2 fibroblast growth factor 2 increases expression ISO Colforsin results in increased expression of FGF2 mRNA; Colforsin results in increased expression of FGF2 protein CTD PMID:10320526 NCBI chr 3:37,402,616...37,464,255
Ensembl chr 3:37,402,495...37,464,257
JBrowse link
G Fgf5 fibroblast growth factor 5 decreases expression ISO Colforsin results in decreased expression of FGF5 mRNA CTD PMID:11598998 NCBI chr 5:98,402,108...98,424,892
Ensembl chr 5:98,402,043...98,424,889
JBrowse link
G Fgf8 fibroblast growth factor 8 increases activity ISO Colforsin results in increased activity of FGF8 protein CTD PMID:15193767 NCBI chr19:45,724,930...45,731,380
Ensembl chr19:45,725,237...45,731,354
JBrowse link
G Fgf9 fibroblast growth factor 9 multiple interactions ISO FGF9 protein inhibits the reaction [Colforsin promotes the reaction [IGF1 protein results in increased abundance of Estradiol]]; FGF9 protein inhibits the reaction [IGF1 protein promotes the reaction [Colforsin results in increased abundance of Progesterone]] CTD PMID:22798350 NCBI chr14:58,308,543...58,350,311
Ensembl chr14:58,308,004...58,350,177
JBrowse link
G Fgfr1 fibroblast growth factor receptor 1 increases expression ISO Colforsin results in increased expression of FGFR1 mRNA CTD PMID:10320526 NCBI chr 8:26,008,808...26,067,819
Ensembl chr 8:26,003,670...26,065,734
JBrowse link
G Fgfr2 fibroblast growth factor receptor 2 increases expression ISO Colforsin results in increased expression of FGFR2 mRNA CTD PMID:10320526 NCBI chr 7:129,764,181...129,868,538
Ensembl chr 7:129,764,181...132,725,079
JBrowse link
G Fkbp5 FK506 binding protein 5 multiple interactions ISO Colforsin promotes the reaction [Dexamethasone results in increased expression of FKBP5 mRNA] CTD PMID:19255438 NCBI chr17:28,617,727...28,705,123
Ensembl chr17:28,618,068...28,736,501
JBrowse link
G Flt1 FMS-like tyrosine kinase 1 increases expression ISO Colforsin results in increased expression of FLT1 mRNA CTD PMID:33144174 NCBI chr 5:147,498,414...147,663,419
Ensembl chr 5:147,498,414...147,662,821
JBrowse link
G Fos FBJ osteosarcoma oncogene increases expression
multiple interactions
ISO Colforsin results in increased expression of FOS protein
Dexamethasone inhibits the reaction [Colforsin results in increased expression of FOS protein]
CTD PMID:11113530 NCBI chr12:85,520,664...85,524,048
Ensembl chr12:85,520,664...85,524,047
JBrowse link
G Fosb FBJ osteosarcoma oncogene B increases expression ISO Colforsin results in increased expression of FOSB mRNA; Colforsin results in increased expression of FOSB protein CTD PMID:11113530 PMID:17324382 NCBI chr 7:19,036,621...19,043,970
Ensembl chr 7:19,036,621...19,043,976
JBrowse link
G Fshb follicle stimulating hormone beta increases expression ISO Colforsin results in increased expression of FSHB mRNA; Colforsin results in increased expression of FSHB protein CTD PMID:8404651 NCBI chr 2:106,886,331...106,889,996
Ensembl chr 2:106,886,485...106,890,001
JBrowse link
G Fst follistatin multiple interactions ISO FST protein inhibits the reaction [BMP6 protein inhibits the reaction [Colforsin results in increased secretion of Progesterone]]; FST protein inhibits the reaction [INHBA protein inhibits the reaction [Colforsin results in increased secretion of Progesterone]] CTD PMID:18936084 NCBI chr13:114,588,798...114,595,522
Ensembl chr13:114,588,826...114,595,487
JBrowse link
G G6pc1 glucose-6-phosphatase catalytic subunit 1 multiple interactions ISO [Dexamethasone co-treated with Colforsin] results in increased expression of G6PC1 mRNA
Colforsin inhibits the reaction [Leflunomide results in increased expression of G6PC1 mRNA]; Colforsin inhibits the reaction [teriflunomide results in increased expression of G6PC1 mRNA]
CTD PMID:18972406 PMID:30364229 NCBI chr11:101,258,542...101,268,729
Ensembl chr11:101,258,387...101,268,729
JBrowse link
G Gabra1 gamma-aminobutyric acid type A receptor subunit alpha 1 increases expression ISO Colforsin results in increased expression of GABRA1 CTD PMID:9147380 NCBI chr11:42,021,766...42,073,893
Ensembl chr11:42,021,766...42,073,757
JBrowse link
G