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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:organic halide salt
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Accession:CHEBI:51069 term browser browse the term
Synonyms:related_synonym: organic halide salts



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(1R,3S)-3-(adamantan-1-yl)-1-(aminomethyl)-3,4-dihydroisochromene-5,6-diol hydrochloride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DRD1 dopamine receptor D1 multiple interactions
affects localization
EXP A 77636 binds to and results in increased activity of DRD1 protein; SCH 23390 inhibits the reaction [A 77636 affects the localization of DRD1 protein]; SCH 23390 inhibits the reaction [A 77636 results in increased activity of DRD1 protein] CTD PMID:15985612 NCBI chr 5:175,440,036...175,444,182
Ensembl chr 5:175,440,036...175,444,182
JBrowse link
(S)-duloxetine hydrochloride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKT1 AKT serine/threonine kinase 1 multiple interactions ISO Duloxetine Hydrochloride inhibits the reaction [Indomethacin results in decreased phosphorylation of AKT1 protein] CTD PMID:38701902 NCBI chr14:104,769,349...104,795,748
Ensembl chr14:104,769,349...104,795,759
JBrowse link
G AR androgen receptor multiple interactions EXP Duloxetine Hydrochloride binds to and results in decreased activity of AR protein CTD PMID:25752796 NCBI chr  X:67,544,021...67,730,619
Ensembl chr  X:67,544,021...67,730,619
JBrowse link
G CD48 CD48 molecule multiple interactions ISO Duloxetine Hydrochloride inhibits the reaction [Indomethacin results in increased expression of CD48 protein] CTD PMID:38701902 NCBI chr 1:160,678,746...160,711,822
Ensembl chr 1:160,678,746...160,711,831
JBrowse link
G CYP17A1 cytochrome P450 family 17 subfamily A member 1 decreases activity
multiple interactions
EXP Duloxetine Hydrochloride results in decreased activity of CYP17A1 protein
Duloxetine Hydrochloride inhibits the reaction [[CYP17A1 protein results in increased hydroxylation of Pregnenolone] which results in increased chemical synthesis of 17-alpha-Hydroxypregnenolone]; Duloxetine Hydrochloride inhibits the reaction [[CYP17A1 protein results in increased hydroxylation of Progesterone] which results in increased chemical synthesis of 17-alpha-Hydroxyprogesterone]; Duloxetine Hydrochloride inhibits the reaction [[CYP17A1 protein results in increased metabolism of 17-alpha-Hydroxypregnenolone] which results in increased chemical synthesis of Dehydroepiandrosterone]; Duloxetine Hydrochloride inhibits the reaction [[CYP17A1 protein results in increased metabolism of 17-alpha-Hydroxyprogesterone] which results in increased chemical synthesis of Androstenedione]; Duloxetine Hydrochloride inhibits the reaction [CYP17A1 protein results in increased hydroxylation of Pregnenolone]; Duloxetine Hydrochloride inhibits the reaction [CYP17A1 protein results in increased hydroxylation of Progesterone]; Duloxetine Hydrochloride inhibits the reaction [CYP17A1 protein results in increased metabolism of 17-alpha-Hydroxypregnenolone]; Duloxetine Hydrochloride inhibits the reaction [CYP17A1 protein results in increased metabolism of 17-alpha-Hydroxyprogesterone]
CTD PMID:29100959 NCBI chr10:102,830,531...102,837,413
Ensembl chr10:102,830,531...102,837,472
JBrowse link
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 decreases activity EXP Duloxetine Hydrochloride results in decreased activity of CYP1A1 protein CTD PMID:33814510 NCBI chr15:74,719,542...74,725,528
Ensembl chr15:74,719,542...74,725,536
JBrowse link
G CYP1A2 cytochrome P450 family 1 subfamily A member 2 multiple interactions ISO [furafylline results in decreased activity of CYP1A2 protein] which results in decreased glutathionylation of Duloxetine Hydrochloride; CYP1A2 protein results in increased activity of and results in increased glutathionylation of Duloxetine Hydrochloride CTD PMID:20669986 NCBI chr15:74,748,845...74,756,607
Ensembl chr15:74,748,845...74,756,607
JBrowse link
G CYP1B1 cytochrome P450 family 1 subfamily B member 1 decreases activity EXP Duloxetine Hydrochloride results in decreased activity of CYP1B1 protein CTD PMID:33814510 NCBI chr 2:38,067,509...38,076,151
Ensembl chr 2:38,066,973...38,109,902
JBrowse link
G CYP2D6 cytochrome P450 family 2 subfamily D member 6 (gene/pseudogene) multiple interactions ISO [Quinidine results in decreased activity of CYP2D6 protein] which results in decreased glutathionylation of Duloxetine Hydrochloride; CYP2D6 protein results in increased activity of and results in increased glutathionylation of Duloxetine Hydrochloride CTD PMID:20669986 NCBI chr22:42,126,499...42,130,810
Ensembl chr22:42,126,499...42,130,865
JBrowse link
G HMOX1 heme oxygenase 1 increases expression EXP Duloxetine Hydrochloride results in increased expression of HMOX1 mRNA CTD PMID:29134401 NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214
JBrowse link
G IL1A interleukin 1 alpha multiple interactions ISO Duloxetine Hydrochloride inhibits the reaction [Indomethacin results in increased expression of IL1A protein] CTD PMID:38701902 NCBI chr 2:112,773,925...112,784,493
Ensembl chr 2:112,773,925...112,784,493
JBrowse link
G KCNH2 potassium voltage-gated channel subfamily H member 2 decreases activity EXP Duloxetine Hydrochloride results in decreased activity of KCNH2 protein CTD PMID:28551711 NCBI chr 7:150,944,961...150,978,321
Ensembl chr 7:150,944,961...150,978,321
JBrowse link
G KCNJ3 potassium inwardly rectifying channel subfamily J member 3 multiple interactions ISO Duloxetine Hydrochloride results in decreased activity of [KCNJ3 mRNA co-treated with KCNJ5 mRNA]; Duloxetine Hydrochloride results in decreased activity of [KCNJ3 mRNA co-treated with KCNJ6 mRNA] CTD PMID:22164246 NCBI chr 2:154,698,695...154,858,354
Ensembl chr 2:154,697,855...154,858,354
JBrowse link
G KCNJ5 potassium inwardly rectifying channel subfamily J member 5 multiple interactions ISO Duloxetine Hydrochloride results in decreased activity of [KCNJ3 mRNA co-treated with KCNJ5 mRNA] CTD PMID:22164246 NCBI chr11:128,891,356...128,921,163
Ensembl chr11:128,891,356...128,921,163
JBrowse link
G KCNJ6 potassium inwardly rectifying channel subfamily J member 6 multiple interactions ISO Duloxetine Hydrochloride results in decreased activity of [KCNJ3 mRNA co-treated with KCNJ6 mRNA] CTD PMID:22164246 NCBI chr21:37,607,373...37,916,457
Ensembl chr21:37,607,373...38,121,345
JBrowse link
G NFE2L2 NFE2 like bZIP transcription factor 2 affects localization EXP Duloxetine Hydrochloride affects the localization of NFE2L2 protein CTD PMID:29134401 NCBI chr 2:177,230,303...177,264,727
Ensembl chr 2:177,218,667...177,392,756
JBrowse link
G PRL prolactin increases expression EXP Duloxetine Hydrochloride results in increased expression of PRL protein CTD PMID:17606668 NCBI chr 6:22,287,246...22,302,835
Ensembl chr 6:22,287,244...22,302,826
JBrowse link
G VEGFA vascular endothelial growth factor A multiple interactions ISO Duloxetine Hydrochloride inhibits the reaction [Indomethacin results in decreased expression of VEGFA protein] CTD PMID:38701902 NCBI chr 6:43,770,211...43,786,487
Ensembl chr 6:43,770,184...43,786,487
JBrowse link
1,1-dimethyl-4-phenylpiperazinium iodide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CHRNA2 cholinergic receptor nicotinic alpha 2 subunit multiple interactions EXP
ISO
Dimethylphenylpiperazinium Iodide results in increased activity of [CHRNB4 protein binds to CHRNA2 protein]
1,1-dimethyl-4-phenylpiperazinium iodide affects binding competes with [Epibatidine binds to Chrna2 protein]
CTD
RGD
PMID:9454827 PMID:15016836 RGD:2303194 NCBI chr 8:27,459,756...27,479,261
Ensembl chr 8:27,459,756...27,479,883
JBrowse link
G CHRNA3 cholinergic receptor nicotinic alpha 3 subunit multiple interactions EXP
ISO
Dimethylphenylpiperazinium Iodide results in increased activity of [CHRNB4 protein binds to CHRNA3 protein]
1,1-dimethyl-4-phenylpiperazinium iodide affects binding [Epibatidine binds to Chrna3 protein]
CTD
RGD
PMID:9454827 PMID:15016836 RGD:2303194 NCBI chr15:78,593,052...78,620,996
Ensembl chr15:78,593,052...78,621,295
JBrowse link
G CHRNA4 cholinergic receptor nicotinic alpha 4 subunit multiple interactions EXP
ISO
Dimethylphenylpiperazinium Iodide inhibits the reaction [epibatidine binds to [CHRNA4 protein binds to CHRNB2 protein]]; Dimethylphenylpiperazinium Iodide results in increased activity of [CHRNA4 protein binds to CHRNB2 protein]; Dimethylphenylpiperazinium Iodide results in increased activity of [CHRNB4 protein binds to CHRNA4 protein]
1,1-dimethyl-4-phenylpiperazinium iodide affects binding to Chrna4 protein; 1,1-dimethyl-4-phenylpiperazinium iodide competes with [Epibatidine binds to Chrna4 protein]
CTD
RGD
PMID:9454827 PMID:14645658 PMID:15016836 RGD:2303194 NCBI chr20:63,343,223...63,361,349
Ensembl chr20:63,343,223...63,378,401
JBrowse link
G CHRNA7 cholinergic receptor nicotinic alpha 7 subunit multiple interactions
increases response to substance
increases activity
EXP Dimethylphenylpiperazinium Iodide inhibits the reaction [Bungarotoxins binds to CHRNA7 protein]
CHRNA7 protein mutant form results in increased susceptibility to Dimethylphenylpiperazinium Iodide
Dimethylphenylpiperazinium Iodide results in increased activity of CHRNA7 protein
CTD PMID:10082212 PMID:10216184 NCBI chr15:32,030,483...32,173,018
Ensembl chr15:31,923,438...32,173,018
JBrowse link
G CHRNB2 cholinergic receptor nicotinic beta 2 subunit multiple interactions EXP
ISO
Dimethylphenylpiperazinium Iodide inhibits the reaction [epibatidine binds to [CHRNA4 protein binds to CHRNB2 protein]]; Dimethylphenylpiperazinium Iodide results in increased activity of [CHRNA4 protein binds to CHRNB2 protein]
1,1-dimethyl-4-phenylpiperazinium iodide affects binding to Chrnb2 protein; 1,1-dimethyl-4-phenylpiperazinium iodide competes with [Epibatidine binds to Chrnb2 protein]
CTD
RGD
PMID:14645658 PMID:15016836 RGD:2303194 NCBI chr 1:154,567,778...154,580,013
Ensembl chr 1:154,567,778...154,580,013
JBrowse link
G CHRNB4 cholinergic receptor nicotinic beta 4 subunit multiple interactions EXP Dimethylphenylpiperazinium Iodide results in increased activity of [CHRNB4 protein binds to CHRNA2 protein]; Dimethylphenylpiperazinium Iodide results in increased activity of [CHRNB4 protein binds to CHRNA3 protein]; Dimethylphenylpiperazinium Iodide results in increased activity of [CHRNB4 protein binds to CHRNA4 protein] CTD PMID:9454827 NCBI chr15:78,624,111...78,661,641
Ensembl chr15:78,624,111...78,727,754
JBrowse link
G TNF tumor necrosis factor increases activity ISO TNF results in increased activity of Dimethylphenylpiperazinium Iodide CTD PMID:15086448 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336
JBrowse link
3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB1 ATP binding cassette subfamily B member 1 decreases activity EXP thiazolyl blue results in decreased activity of ABCB1 protein CTD PMID:15451006 NCBI chr 7:87,503,017...87,713,295
Ensembl chr 7:87,503,017...87,713,323
JBrowse link
G ACO2 aconitase 2 multiple interactions ISO [Calcium results in increased activity of ACO2 protein] which results in increased reduction of thiazolyl blue; [Potassium deficiency results in decreased activity of ACO2 protein] which results in decreased reduction of thiazolyl blue CTD PMID:12548706 NCBI chr22:41,469,117...41,528,974
Ensembl chr22:41,447,830...41,529,273
JBrowse link
G CASP3 caspase 3 increases activity EXP thiazolyl blue results in increased activity of CASP3 protein CTD PMID:22401948 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062
JBrowse link
G CASP8 caspase 8 increases activity EXP thiazolyl blue results in increased activity of CASP8 protein CTD PMID:22401948 NCBI chr 2:201,233,463...201,287,711
Ensembl chr 2:201,233,443...201,361,836
JBrowse link
G NQO2 N-ribosyldihydronicotinamide:quinone dehydrogenase 2 increases reduction
multiple interactions
EXP NQO2 protein results in increased reduction of thiazolyl blue
resveratrol inhibits the reaction [NQO2 protein results in increased reduction of thiazolyl blue]; Tacrine inhibits the reaction [NQO2 protein results in increased reduction of thiazolyl blue]
CTD PMID:29281794 NCBI chr 6:2,999,894...3,019,755
Ensembl chr 6:2,987,987...3,019,755
JBrowse link
3beta-(2-diethylaminoethoxy)androst-5-en-17-one hydrochloride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GPC1 glypican 1 decreases degradation ISO 3-beta-(2-(diethylamino)ethoxy)androst-5-en-17-one results in decreased degradation of GPC1 protein CTD PMID:21642435 NCBI chr 2:240,435,663...240,468,076
Ensembl chr 2:240,435,663...240,468,076
JBrowse link
G IL1B interleukin 1 beta multiple interactions ISO 3-beta-(2-(diethylamino)ethoxy)androst-5-en-17-one inhibits the reaction [[Lipopolysaccharides results in increased susceptibility to Silicon Dioxide] which results in increased secretion of IL1B protein] CTD PMID:36860548 NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816
JBrowse link
4-fluoro-N-\{2-[4-(7-methoxynaphthalen-1-yl)piperazin-1-yl]ethyl\}benzamide hydrochloride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HTR1A 5-hydroxytryptamine receptor 1A multiple interactions ISO [1-((4-fluorobenzoylamino)ethyl)-4-(7-methoxy-1-naphthyl)piperazine hydrochloride binds to and results in increased activity of HTR1A protein] which results in decreased susceptibility to 1-(3-chlorophenyl)piperazine; [1-((4-fluorobenzoylamino)ethyl)-4-(7-methoxy-1-naphthyl)piperazine hydrochloride binds to and results in increased activity of HTR1A protein] which results in decreased susceptibility to Apomorphine; [1-((4-fluorobenzoylamino)ethyl)-4-(7-methoxy-1-naphthyl)piperazine hydrochloride binds to and results in increased activity of HTR1A protein] which results in decreased susceptibility to Physostigmine; tertatolol inhibits the reaction [[1-((4-fluorobenzoylamino)ethyl)-4-(7-methoxy-1-naphthyl)piperazine hydrochloride binds to and results in increased activity of HTR1A protein] which results in decreased susceptibility to Apomorphine]; tertatolol inhibits the reaction [[1-((4-fluorobenzoylamino)ethyl)-4-(7-methoxy-1-naphthyl)piperazine hydrochloride binds to and results in increased activity of HTR1A protein] which results in decreased susceptibility to Physostigmine] CTD PMID:8539317 NCBI chr 5:63,957,874...63,962,445
Ensembl chr 5:63,957,874...63,962,507
JBrowse link
acridine orange term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BAX BCL2 associated X, apoptosis regulator increases response to substance EXP BAX protein results in increased susceptibility to Acridine Orange CTD PMID:16177561 NCBI chr19:48,954,875...48,961,798
Ensembl chr19:48,954,815...48,961,798
JBrowse link
G GSTP1 glutathione S-transferase pi 1 multiple interactions EXP [Acridine Orange binds to Platinum Compounds] which results in increased expression of GSTP1 mRNA; [Acridine Orange binds to Platinum] which results in increased expression of GSTP1 mRNA CTD PMID:16814760 NCBI chr11:67,583,812...67,586,653
Ensembl chr11:67,583,742...67,586,656
JBrowse link
G TP53 tumor protein p53 multiple interactions EXP Acridine Orange results in increased stability of and results in increased activity of TP53 protein CTD PMID:16177561 NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,546
JBrowse link
ambenonium chloride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACHE acetylcholinesterase (Yt blood group) decreases activity EXP Ambenonium Chloride results in decreased activity of ACHE protein CTD PMID:33844597 NCBI chr 7:100,889,994...100,896,994
Ensembl chr 7:100,889,994...100,896,974
JBrowse link
G APP amyloid beta precursor protein affects cleavage ISO Ambenonium Chloride affects the cleavage of APP protein CTD PMID:11099780 NCBI chr21:25,880,550...26,171,128
Ensembl chr21:25,880,535...26,171,128
JBrowse link
amprolium term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SLC19A3 solute carrier family 19 member 3 multiple interactions EXP Amprolium inhibits the reaction [SLC19A3 protein results in increased uptake of Metformin]; Amprolium inhibits the reaction [SLC19A3 protein results in increased uptake of Thiamine] CTD PMID:26528626 NCBI chr 2:227,683,763...227,718,028
Ensembl chr 2:227,683,763...227,718,028
JBrowse link
atomoxetine hydrochloride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CYP2D6 cytochrome P450 family 2 subfamily D member 6 (gene/pseudogene) increases hydroxylation
increases metabolic processing
multiple interactions
EXP CYP2D6 protein results in increased hydroxylation of Atomoxetine Hydrochloride
CYP2D6 protein results in increased metabolism of Atomoxetine Hydrochloride
Quinidine inhibits the reaction [CYP2D6 protein results in increased metabolism of Atomoxetine Hydrochloride]
CTD PMID:17470523 PMID:34431675 NCBI chr22:42,126,499...42,130,810
Ensembl chr22:42,126,499...42,130,865
JBrowse link
auramine O term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALDH1A1 aldehyde dehydrogenase 1 family member A1 increases expression
multiple interactions
EXP Benzophenoneidum results in increased expression of ALDH1A1 protein
ALDH1A1 protein promotes the reaction [Benzophenoneidum results in increased lipidation of and results in increased cleavage of MAP1LC3B protein]
CTD PMID:28722353 NCBI chr 9:72,900,671...72,953,053
Ensembl chr 9:72,900,671...73,080,442
JBrowse link
G ANO6 anoctamin 6 increases expression EXP Benzophenoneidum results in increased expression of ANO6 protein CTD PMID:28722353 NCBI chr12:45,216,095...45,440,404
Ensembl chr12:45,215,987...45,482,280
JBrowse link
G ARAF A-Raf proto-oncogene, serine/threonine kinase increases expression EXP Benzophenoneidum results in increased expression of ARAF protein CTD PMID:28722353 NCBI chr  X:47,561,205...47,571,908
Ensembl chr  X:47,561,205...47,571,908
JBrowse link
G ATP6AP2 ATPase H+ transporting accessory protein 2 increases expression EXP Benzophenoneidum results in increased expression of ATP6AP2 protein CTD PMID:28722353 NCBI chr  X:40,580,970...40,606,848
Ensembl chr  X:40,579,372...40,606,848
JBrowse link
G CCDC22 coiled-coil domain containing 22 increases expression EXP Benzophenoneidum results in increased expression of CCDC22 protein CTD PMID:28722353 NCBI chr  X:49,235,470...49,250,520
Ensembl chr  X:49,235,470...49,250,520
JBrowse link
G CCDC39 coiled-coil domain 39 molecular ruler complex subunit increases expression EXP Benzophenoneidum results in increased expression of CCDC39 protein CTD PMID:28722353 NCBI chr 3:180,614,008...180,679,489
Ensembl chr 3:180,602,858...180,684,942
JBrowse link
G CD44 CD44 molecule (IN blood group) increases expression EXP Benzophenoneidum results in increased expression of CD44 protein CTD PMID:28722353 NCBI chr11:35,139,171...35,232,402
Ensembl chr11:35,138,882...35,232,402
JBrowse link
G CHTF18 chromosome transmission fidelity factor 18 increases expression EXP Benzophenoneidum results in increased expression of CHTF18 protein CTD PMID:28722353 NCBI chr16:788,620...798,074
Ensembl chr16:788,046...800,737
JBrowse link
G COMMD1 copper metabolism domain containing 1 increases expression EXP Benzophenoneidum results in increased expression of COMMD1 protein CTD PMID:28722353 NCBI chr 2:61,888,391...62,136,058
Ensembl chr 2:61,888,724...62,147,247
JBrowse link
G COPS7B COP9 signalosome subunit 7B increases expression EXP Benzophenoneidum results in increased expression of COPS7B protein CTD PMID:28722353 NCBI chr 2:231,781,671...231,809,253
Ensembl chr 2:231,781,671...231,809,254
JBrowse link
G CUL3 cullin 3 increases expression EXP Benzophenoneidum results in increased expression of CUL3 protein CTD PMID:28722353 NCBI chr 2:224,470,150...224,585,363
Ensembl chr 2:224,470,150...224,585,397
JBrowse link
G DYNLT1 dynein light chain Tctex-type 1 increases expression EXP Benzophenoneidum results in increased expression of DYNLT1 protein CTD PMID:28722353 NCBI chr 6:158,636,474...158,644,743
Ensembl chr 6:158,636,474...158,644,743
JBrowse link
G EIF4G3 eukaryotic translation initiation factor 4 gamma 3 increases expression EXP Benzophenoneidum results in increased expression of EIF4G3 protein CTD PMID:28722353 NCBI chr 1:20,806,292...21,176,897
Ensembl chr 1:20,806,292...21,177,285
JBrowse link
G FASTKD2 FAST kinase domains 2 increases expression EXP Benzophenoneidum results in increased expression of FASTKD2 protein CTD PMID:28722353 NCBI chr 2:206,765,606...206,796,189
Ensembl chr 2:206,765,357...206,796,189
JBrowse link
G H2AX H2A.X variant histone increases phosphorylation ISO Benzophenoneidum results in increased phosphorylation of H2AX protein CTD PMID:37527026 NCBI chr11:119,093,874...119,095,465
Ensembl chr11:119,093,874...119,095,465
JBrowse link
G HOOK3 hook microtubule tethering protein 3 increases expression EXP Benzophenoneidum results in increased expression of HOOK3 protein CTD PMID:28722353 NCBI chr 8:42,896,978...43,030,535
Ensembl chr 8:42,896,946...43,030,535
JBrowse link
G HSD17B7 hydroxysteroid 17-beta dehydrogenase 7 increases expression EXP Benzophenoneidum results in increased expression of HSD17B7 protein CTD PMID:28722353 NCBI chr 1:162,790,702...162,812,823
Ensembl chr 1:162,790,702...162,812,823
JBrowse link
G HTT huntingtin increases expression EXP Benzophenoneidum results in increased expression of HTT protein CTD PMID:28722353 NCBI chr 4:3,074,681...3,243,960
Ensembl chr 4:3,041,363...3,243,957
JBrowse link
G IQGAP3 IQ motif containing GTPase activating protein 3 increases expression EXP Benzophenoneidum results in increased expression of IQGAP3 protein CTD PMID:28722353 NCBI chr 1:156,525,405...156,572,565
Ensembl chr 1:156,525,405...156,572,604
JBrowse link
G KIFAP3 kinesin associated protein 3 increases expression EXP Benzophenoneidum results in increased expression of KIFAP3 protein CTD PMID:28722353 NCBI chr 1:169,921,329...170,085,184
Ensembl chr 1:169,921,326...170,085,208
JBrowse link
G MAP1LC3B microtubule associated protein 1 light chain 3 beta multiple interactions EXP ALDH1A1 protein promotes the reaction [Benzophenoneidum results in increased lipidation of and results in increased cleavage of MAP1LC3B protein]; Benzophenoneidum results in increased lipidation of and results in increased cleavage of MAP1LC3B protein CTD PMID:28722353 NCBI chr16:87,392,336...87,404,774
Ensembl chr16:87,383,953...87,404,779
JBrowse link
G MAP2K4 mitogen-activated protein kinase kinase 4 increases expression EXP Benzophenoneidum results in increased expression of MAP2K4 protein CTD PMID:28722353 NCBI chr17:12,020,877...12,143,828
Ensembl chr17:12,020,829...12,143,830
JBrowse link
G MBD3 methyl-CpG binding domain protein 3 increases expression EXP Benzophenoneidum results in increased expression of MBD3 protein CTD PMID:28722353 NCBI chr19:1,573,596...1,592,865
Ensembl chr19:1,573,596...1,592,865
JBrowse link
G MKI67 marker of proliferation Ki-67 increases expression ISO Benzophenoneidum results in increased expression of MKI67 protein CTD PMID:37527026 NCBI chr10:128,096,659...128,126,423
Ensembl chr10:128,096,659...128,126,423
JBrowse link
G NOA1 nitric oxide associated 1 increases expression EXP Benzophenoneidum results in increased expression of NOA1 protein CTD PMID:28722353 NCBI chr 4:56,963,350...56,977,606
Ensembl chr 4:56,963,350...56,977,606
JBrowse link
G NUP62 nucleoporin 62 increases expression EXP Benzophenoneidum results in increased expression of NUP62 protein CTD PMID:28722353 NCBI chr19:49,906,825...49,929,504
Ensembl chr19:49,906,825...49,929,764
JBrowse link
G PLCG1 phospholipase C gamma 1 increases expression EXP Benzophenoneidum results in increased expression of PLCG1 protein CTD PMID:28722353 NCBI chr20:41,137,543...41,177,626
Ensembl chr20:41,136,960...41,196,801
JBrowse link
G PPP4R1 protein phosphatase 4 regulatory subunit 1 increases expression EXP Benzophenoneidum results in increased expression of PPP4R1 protein CTD PMID:28722353 NCBI chr18:9,546,794...9,617,199
Ensembl chr18:9,546,791...9,615,240
JBrowse link
G PRIM2 DNA primase subunit 2 increases expression EXP Benzophenoneidum results in increased expression of PRIM2 protein CTD PMID:28722353 NCBI chr 6:57,221,540...57,646,850
Ensembl chr 6:57,314,805...57,646,850
JBrowse link
G PROM1 prominin 1 increases expression EXP Benzophenoneidum results in increased expression of PROM1 protein CTD PMID:28722353 NCBI chr 4:15,968,228...16,084,023
Ensembl chr 4:15,963,076...16,084,378
JBrowse link
G PRORP protein only RNase P catalytic subunit increases expression EXP Benzophenoneidum results in increased expression of PRORP protein CTD PMID:28722353 NCBI chr14:35,121,839...35,277,622
Ensembl chr14:35,121,846...35,277,622
JBrowse link
G SHMT1 serine hydroxymethyltransferase 1 increases expression EXP Benzophenoneidum results in increased expression of SHMT1 protein CTD PMID:28722353 NCBI chr17:18,327,873...18,363,550
Ensembl chr17:18,327,873...18,363,550
JBrowse link
G SRSF11 serine and arginine rich splicing factor 11 increases expression EXP Benzophenoneidum results in increased expression of SRSF11 protein CTD PMID:28722353 NCBI chr 1:70,205,696...70,253,052
Ensembl chr 1:70,205,682...70,253,052
JBrowse link
G TBC1D15 TBC1 domain family member 15 increases expression EXP Benzophenoneidum results in increased expression of TBC1D15 protein CTD PMID:28722353 NCBI chr12:71,839,759...71,924,313
Ensembl chr12:71,839,707...71,927,248
JBrowse link
G TFAM transcription factor A, mitochondrial increases expression EXP Benzophenoneidum results in increased expression of TFAM protein CTD PMID:28722353 NCBI chr10:58,385,410...58,399,220
Ensembl chr10:58,385,345...58,399,220
JBrowse link
G USP24 ubiquitin specific peptidase 24 increases expression EXP Benzophenoneidum results in increased expression of USP24 protein CTD PMID:28722353 NCBI chr 1:55,066,359...55,215,364
Ensembl chr 1:55,066,359...55,215,378
JBrowse link
G WASHC5 WASH complex subunit 5 increases expression EXP Benzophenoneidum results in increased expression of WASHC5 protein CTD PMID:28722353 NCBI chr 8:125,024,260...125,091,792
Ensembl chr 8:125,024,260...125,091,819
JBrowse link
azure A term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GPT glutamic--pyruvic transaminase increases activity ISO Azure A results in increased activity of GPT protein CTD PMID:33775737 NCBI chr 8:144,503,068...144,507,172
Ensembl chr 8:144,502,973...144,507,174
JBrowse link
azure B term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APP amyloid beta precursor protein multiple interactions EXP [Azure B affects the cleavage of APP protein] which results in decreased secretion of APP protein modified form; Azure B results in decreased expression of and affects the cleavage of APP protein CTD PMID:30500345 NCBI chr21:25,880,550...26,171,128
Ensembl chr21:25,880,535...26,171,128
JBrowse link
G BACE1 beta-secretase 1 decreases activity EXP Azure B results in decreased activity of BACE1 protein CTD PMID:30500345 NCBI chr11:117,285,698...117,316,256
Ensembl chr11:117,285,232...117,316,259
JBrowse link
benzalkonium chloride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AACS acetoacetyl-CoA synthetase increases expression ISO Benzalkonium Compounds results in increased expression of AACS mRNA CTD PMID:31199489 NCBI chr12:125,065,435...125,143,316
Ensembl chr12:125,065,434...125,143,333
JBrowse link
G ABCA1 ATP binding cassette subfamily A member 1 decreases expression EXP Benzalkonium Compounds results in decreased expression of ABCA1 mRNA CTD PMID:26919959 NCBI chr 9:104,781,006...104,928,155
Ensembl chr 9:104,781,006...104,928,155
JBrowse link
G ABCA12 ATP binding cassette subfamily A member 12 increases expression EXP Benzalkonium Compounds results in increased expression of ABCA12 mRNA CTD PMID:25377654 NCBI chr 2:214,931,542...215,138,626
Ensembl chr 2:214,931,542...215,138,626
JBrowse link
G ABCA6 ATP binding cassette subfamily A member 6 decreases expression EXP Benzalkonium Compounds results in decreased expression of ABCA6 mRNA CTD PMID:20713136 NCBI chr17:69,078,702...69,141,895
Ensembl chr17:69,078,702...69,141,895
JBrowse link
G ACOD1 aconitate decarboxylase 1 increases expression ISO Benzalkonium Compounds results in increased expression of ACOD1 mRNA CTD PMID:30171875 NCBI chr13:76,948,511...76,958,638
Ensembl chr13:76,948,511...76,958,638
JBrowse link
G ACP6 acid phosphatase 6, lysophosphatidic increases expression ISO Benzalkonium Compounds results in increased expression of ACP6 mRNA CTD PMID:31199489 NCBI chr 1:147,629,658...147,670,524
Ensembl chr 1:147,629,652...147,670,524
JBrowse link
G ACSL4 acyl-CoA synthetase long chain family member 4 increases expression ISO Benzalkonium Compounds results in increased expression of ACSL4 mRNA CTD PMID:31199489 NCBI chr  X:109,641,335...109,733,257
Ensembl chr  X:109,624,244...109,733,403
JBrowse link
G ADA adenosine deaminase increases expression ISO Benzalkonium Compounds results in increased expression of ADA mRNA CTD PMID:30171875 NCBI chr20:44,619,522...44,651,699
Ensembl chr20:44,584,896...44,652,252
JBrowse link
G ADH1C alcohol dehydrogenase 1C (class I), gamma polypeptide decreases expression ISO Benzalkonium Compounds results in decreased expression of ADH1 mRNA CTD PMID:31199489 NCBI chr 4:99,336,497...99,352,746
Ensembl chr 4:99,336,497...99,352,746
JBrowse link
G ADORA1 adenosine A1 receptor decreases expression ISO Benzalkonium Compounds results in decreased expression of ADORA1 mRNA CTD PMID:30171875 NCBI chr 1:203,127,726...203,167,405
Ensembl chr 1:203,090,654...203,167,405
JBrowse link
G ADRA2A adrenoceptor alpha 2A multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of ADRA2A mRNA CTD PMID:30171875 NCBI chr10:111,077,029...111,080,907
Ensembl chr10:111,077,029...111,080,907
JBrowse link
G AGTR2 angiotensin II receptor type 2 multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of AGTR2 mRNA CTD PMID:30171875 NCBI chr  X:116,170,744...116,174,974
Ensembl chr  X:116,170,744...116,174,974
JBrowse link
G AKR1B10 aldo-keto reductase family 1 member B10 increases expression EXP Benzalkonium Compounds results in increased expression of AKR1B10 mRNA CTD PMID:30806763 NCBI chr 7:134,527,567...134,541,412
Ensembl chr 7:134,527,567...134,541,412
JBrowse link
G ALB albumin decreases expression ISO Benzalkonium Compounds results in decreased expression of ALB mRNA CTD PMID:31199489 NCBI chr 4:73,404,287...73,421,482
Ensembl chr 4:73,397,114...73,421,482
JBrowse link
G AMIGO2 adhesion molecule with Ig like domain 2 increases expression EXP Benzalkonium Compounds results in increased expression of AMIGO2 mRNA CTD PMID:37149095 NCBI chr12:47,075,707...47,079,959
Ensembl chr12:47,075,707...47,079,959
JBrowse link
G APOA1 apolipoprotein A1 decreases expression ISO Benzalkonium Compounds results in decreased expression of APOA1 mRNA CTD PMID:31199489 NCBI chr11:116,835,751...116,837,622
Ensembl chr11:116,835,751...116,837,622
JBrowse link
G APOA2 apolipoprotein A2 decreases expression ISO Benzalkonium Compounds results in decreased expression of APOA2 mRNA CTD PMID:31199489 NCBI chr 1:161,222,292...161,223,628
Ensembl chr 1:161,222,290...161,223,631
JBrowse link
G APOC1 apolipoprotein C1 decreases expression ISO Benzalkonium Compounds results in decreased expression of APOC1 mRNA CTD PMID:31199489 NCBI chr19:44,914,325...44,919,346
Ensembl chr19:44,914,247...44,919,349
JBrowse link
G AQP3 aquaporin 3 (Gill blood group) increases expression ISO Benzalkonium Compounds results in increased expression of AQP3 mRNA CTD PMID:30171875 NCBI chr 9:33,441,160...33,447,593
Ensembl chr 9:33,441,156...33,447,596
JBrowse link
G AREG amphiregulin increases expression ISO Benzalkonium Compounds results in increased expression of AREG mRNA CTD PMID:30171875 NCBI chr 4:74,445,136...74,455,005
Ensembl chr 4:74,445,136...74,455,005
JBrowse link
G ARG2 arginase 2 increases expression ISO Benzalkonium Compounds results in increased expression of ARG2 mRNA CTD PMID:30171875 NCBI chr14:67,619,920...67,651,708
Ensembl chr14:67,619,920...67,651,708
JBrowse link
G ART3 ADP-ribosyltransferase 3 (inactive) decreases expression ISO Benzalkonium Compounds results in decreased expression of ART3 mRNA CTD PMID:31199489 NCBI chr 4:76,011,190...76,112,786
Ensembl chr 4:76,011,184...76,114,048
JBrowse link
G ATF4 activating transcription factor 4 decreases expression EXP Benzalkonium Compounds results in decreased expression of ATF4 mRNA CTD PMID:28236482 NCBI chr22:39,520,559...39,522,686
Ensembl chr22:39,519,695...39,522,686
JBrowse link
G ATP5F1E ATP synthase F1 subunit epsilon decreases expression ISO Benzalkonium Compounds results in decreased expression of ATP5F1E mRNA CTD PMID:31199489 NCBI chr20:59,025,475...59,032,335
Ensembl chr20:59,025,475...59,032,345
JBrowse link
G ATP5MG ATP synthase membrane subunit g decreases expression ISO Benzalkonium Compounds results in decreased expression of ATP5MG mRNA CTD PMID:31199489 NCBI chr11:118,401,606...118,409,847
Ensembl chr11:118,401,346...118,433,278
JBrowse link
G B3GALT4 beta-1,3-galactosyltransferase 4 affects response to substance EXP B3GALT4 SNP affects the susceptibility to Benzalkonium Compounds CTD PMID:27258892 NCBI chr 6:33,277,123...33,278,825
Ensembl chr 6:33,277,123...33,284,832
JBrowse link
G BAMBI BMP and activin membrane bound inhibitor increases expression EXP Benzalkonium Compounds results in increased expression of BAMBI mRNA CTD PMID:20146380 NCBI chr10:28,677,521...28,682,932
Ensembl chr10:28,677,510...28,682,932
JBrowse link
G BCL3 BCL3 transcription coactivator increases expression ISO Benzalkonium Compounds results in increased expression of BCL3 mRNA CTD PMID:30171875 NCBI chr19:44,747,705...44,760,044
Ensembl chr19:44,747,705...44,760,044
JBrowse link
G BTC betacellulin decreases expression ISO Benzalkonium Compounds results in decreased expression of BTC mRNA CTD PMID:30171875 NCBI chr 4:74,744,759...74,794,523
Ensembl chr 4:74,744,759...74,794,523
JBrowse link
G C3 complement C3 multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of C3 mRNA CTD PMID:30171875 NCBI chr19:6,677,704...6,720,650
Ensembl chr19:6,677,704...6,730,562
JBrowse link
G CASP3 caspase 3 multiple interactions
increases cleavage
EXP benzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketone inhibits the reaction [Benzalkonium Compounds analog results in increased cleavage of CASP3 protein] CTD PMID:31982400 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062
JBrowse link
G CASP8 caspase 8 decreases expression EXP Benzalkonium Compounds results in decreased expression of CASP8 mRNA CTD PMID:28236482 NCBI chr 2:201,233,463...201,287,711
Ensembl chr 2:201,233,443...201,361,836
JBrowse link
G CCL11 C-C motif chemokine ligand 11 increases expression ISO Benzalkonium Compounds results in increased expression of CCL11 protein CTD PMID:30517752 NCBI chr17:34,285,742...34,288,334
Ensembl chr17:34,285,742...34,288,334
JBrowse link
G CCL2 C-C motif chemokine ligand 2 increases expression
increases secretion
ISO
EXP
Benzalkonium Compounds results in increased expression of CCL2 mRNA; Benzalkonium Compounds results in increased expression of CCL2 protein
Benzalkonium Compounds results in increased secretion of CCL2 protein
CTD PMID:30171875 PMID:30517752 PMID:31707104 NCBI chr17:34,255,285...34,257,203
Ensembl chr17:34,255,274...34,257,208
JBrowse link
G CCL20 C-C motif chemokine ligand 20 increases expression EXP Benzalkonium Compounds results in increased expression of CCL20 mRNA CTD PMID:30806763 NCBI chr 2:227,813,842...227,817,556
Ensembl chr 2:227,805,739...227,817,564
JBrowse link
G CCL24 C-C motif chemokine ligand 24 decreases expression ISO Benzalkonium Compounds results in decreased expression of CCL24 mRNA CTD PMID:30171875 NCBI chr 7:75,810,825...75,823,372
Ensembl chr 7:75,810,825...75,823,356
JBrowse link
G CCL3 C-C motif chemokine ligand 3 increases expression
multiple interactions
ISO Benzalkonium Compounds results in increased expression of CCL3 protein
[IL6RA gene mutant form results in increased susceptibility to Benzalkonium Compounds] which results in increased expression of CCL3 protein
CTD PMID:30517752 PMID:31158415 NCBI chr17:36,088,256...36,090,143
Ensembl chr17:36,088,256...36,090,169
JBrowse link
G CCL4 C-C motif chemokine ligand 4 decreases expression
multiple interactions
increases expression
EXP
ISO
Benzalkonium Compounds results in decreased expression of CCL4 mRNA; Benzalkonium Compounds results in decreased expression of CCL4 protein
[IL6RA gene mutant form results in increased susceptibility to Benzalkonium Compounds] which results in increased expression of CCL4 protein
Benzalkonium Compounds results in increased expression of CCL4 protein
CTD PMID:18353026 PMID:20713136 PMID:30517752 PMID:31158415 NCBI chr17:36,103,827...36,105,614
Ensembl chr17:36,103,827...36,105,621
JBrowse link
G CCL5 C-C motif chemokine ligand 5 increases expression ISO Benzalkonium Compounds results in increased expression of CCL5 protein CTD PMID:30517752 NCBI chr17:35,871,491...35,880,360
Ensembl chr17:35,871,491...35,880,793
JBrowse link
G CCL7 C-C motif chemokine ligand 7 increases expression ISO Benzalkonium Compounds results in increased expression of CCL7 mRNA; Benzalkonium Compounds results in increased expression of CCL7 protein CTD PMID:30171875 PMID:30517752 NCBI chr17:34,270,221...34,272,242
Ensembl chr17:34,270,221...34,272,242
JBrowse link
G CCN2 cellular communication network factor 2 decreases expression EXP Benzalkonium Compounds results in decreased expression of CCN2 mRNA CTD PMID:25377654 NCBI chr 6:131,948,176...131,951,372
Ensembl chr 6:131,948,176...131,951,372
JBrowse link
G CCN3 cellular communication network factor 3 increases expression ISO Benzalkonium Compounds results in increased expression of CCN3 mRNA CTD PMID:30171875 NCBI chr 8:119,416,446...119,424,434
Ensembl chr 8:119,416,446...119,424,434
JBrowse link
G CCR4 C-C motif chemokine receptor 4 decreases expression ISO Benzalkonium Compounds results in decreased expression of CCR4 mRNA CTD PMID:30171875 NCBI chr 3:32,951,644...32,956,349
Ensembl chr 3:32,951,644...32,957,120
JBrowse link
G CCR5 C-C motif chemokine receptor 5 increases expression ISO Benzalkonium Compounds results in increased expression of CCR5 mRNA CTD PMID:30171875 NCBI chr 3:46,370,142...46,376,206
Ensembl chr 3:46,370,946...46,376,206
JBrowse link
G CD177 CD177 molecule multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of CD177 mRNA CTD PMID:30171875 NCBI chr19:43,353,686...43,366,081
Ensembl chr19:43,353,686...43,363,172
JBrowse link
G CD274 CD274 molecule multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of CD274 mRNA CTD PMID:30171875 NCBI chr 9:5,450,542...5,470,554
Ensembl chr 9:5,450,503...5,470,566
JBrowse link
G CDC6 cell division cycle 6 multiple interactions
decreases expression
EXP 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one promotes the reaction [Benzalkonium Compounds results in decreased expression of CDC6 protein]
Benzalkonium Compounds results in decreased expression of CDC6 mRNA; Benzalkonium Compounds results in decreased expression of CDC6 protein
CTD PMID:36725023 NCBI chr17:40,287,879...40,304,657
Ensembl chr17:40,287,879...40,304,657
JBrowse link
G CFAP61 cilia and flagella associated protein 61 increases expression ISO Benzalkonium Compounds results in increased expression of CFAP61 mRNA CTD PMID:31199489 NCBI chr20:20,052,532...20,360,698
Ensembl chr20:20,052,514...20,360,703
JBrowse link
G CFD complement factor D decreases expression ISO Benzalkonium Compounds results in decreased expression of CFD mRNA CTD PMID:30171875 NCBI chr19:859,664...863,641
Ensembl chr19:859,453...867,884
JBrowse link
G CHI3L1 chitinase 3 like 1 increases expression ISO Benzalkonium Compounds results in increased expression of CHI3L1 mRNA CTD PMID:30171875 NCBI chr 1:203,178,931...203,186,704
Ensembl chr 1:203,178,931...203,186,704
JBrowse link
G CHRNB4 cholinergic receptor nicotinic beta 4 subunit decreases expression ISO Benzalkonium Compounds results in decreased expression of CHRNB4 mRNA CTD PMID:30171875 NCBI chr15:78,624,111...78,661,641
Ensembl chr15:78,624,111...78,727,754
JBrowse link
G CIMAP1D CIMAP1 family member D decreases expression ISO Benzalkonium Compounds results in decreased expression of CIMAP1D mRNA CTD PMID:30171875 NCBI chr19:463,361...491,624
Ensembl chr19:463,346...474,983
JBrowse link
G CLCF1 cardiotrophin like cytokine factor 1 increases expression ISO Benzalkonium Compounds results in increased expression of CLCF1 mRNA CTD PMID:30171875 NCBI chr11:67,364,168...67,374,177
Ensembl chr11:67,364,168...67,374,177
JBrowse link
G CNFN cornifelin increases expression EXP Benzalkonium Compounds results in increased expression of CNFN mRNA; Benzalkonium Compounds results in increased expression of CNFN protein CTD PMID:25377654 NCBI chr19:42,387,019...42,390,297
Ensembl chr19:42,387,019...42,390,297
JBrowse link
G CSF1 colony stimulating factor 1 increases expression ISO Benzalkonium Compounds results in increased expression of CSF1 protein CTD PMID:30517752 NCBI chr 1:109,910,506...109,930,992
Ensembl chr 1:109,910,242...109,930,992
JBrowse link
G CSF2 colony stimulating factor 2 increases expression ISO Benzalkonium Compounds results in increased expression of CSF2 protein CTD PMID:30517752 NCBI chr 5:132,073,789...132,076,170
Ensembl chr 5:132,073,789...132,076,170
JBrowse link
G CSF3 colony stimulating factor 3 increases expression ISO Benzalkonium Compounds results in increased expression of CSF3 protein CTD PMID:30517752 NCBI chr17:40,015,440...40,017,813
Ensembl chr17:40,015,361...40,017,813
JBrowse link
G CTPS1 CTP synthase 1 multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of CTPS1 mRNA CTD PMID:30171875 NCBI chr 1:40,979,696...41,012,565
Ensembl chr 1:40,979,300...41,012,565
JBrowse link
G CXCL1 C-X-C motif chemokine ligand 1 increases expression
multiple interactions
ISO Benzalkonium Compounds results in increased expression of CXCL1 protein; Benzalkonium Compounds results in increased expression of CXCL3 mRNA
[IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of CXCL3 mRNA
CTD PMID:30171875 PMID:30517752 NCBI chr 4:73,869,393...73,871,308
Ensembl chr 4:73,869,393...73,871,308
JBrowse link
G CXCL10 C-X-C motif chemokine ligand 10 increases expression
multiple interactions
ISO Benzalkonium Compounds results in increased expression of CXCL10 mRNA; Benzalkonium Compounds results in increased expression of CXCL10 protein
[IL6RA gene mutant form results in increased susceptibility to Benzalkonium Compounds] which results in increased expression of CXCL10 protein
CTD PMID:23445166 PMID:30517752 PMID:31158415 NCBI chr 4:76,021,118...76,023,497
Ensembl chr 4:76,021,118...76,023,497
JBrowse link
G CXCL2 C-X-C motif chemokine ligand 2 increases expression
multiple interactions
ISO Benzalkonium Compounds results in increased expression of CXCL2 mRNA; Benzalkonium Compounds results in increased expression of CXCL2 protein
[IL6RA gene mutant form results in increased susceptibility to Benzalkonium Compounds] which results in increased expression of CXCL2 protein
CTD PMID:30171875 PMID:30517752 PMID:31158415 NCBI chr 4:74,097,040...74,099,195
Ensembl chr 4:74,097,040...74,099,196
JBrowse link
G CXCL6 C-X-C motif chemokine ligand 6 increases expression
multiple interactions
ISO Benzalkonium Compounds results in increased expression of CXCL5 mRNA; Benzalkonium Compounds results in increased expression of CXCL5 protein
[IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of CXCL5 mRNA
CTD PMID:30171875 PMID:30517752 NCBI chr 4:73,836,678...73,838,760
Ensembl chr 4:73,836,640...73,849,064
JBrowse link
G CXCL8 C-X-C motif chemokine ligand 8 decreases expression
increases expression
increases secretion
decreases secretion
EXP Benzalkonium Compounds results in decreased expression of CXCL8 mRNA; Benzalkonium Compounds results in decreased expression of CXCL8 protein
Benzalkonium Compounds results in increased expression of CXCL8 mRNA
Benzalkonium Compounds results in increased secretion of CXCL8 protein
Benzalkonium Compounds results in decreased secretion of CXCL8 protein
CTD PMID:8006454 PMID:12781210 PMID:16099135 PMID:17763283 PMID:19729060 More... NCBI chr 4:73,740,569...73,743,716
Ensembl chr 4:73,740,519...73,743,716
JBrowse link
G CXCR1 C-X-C motif chemokine receptor 1 increases expression EXP Benzalkonium Compounds results in increased expression of CXCR1 mRNA CTD PMID:30806763 NCBI chr 2:218,162,841...218,166,962
Ensembl chr 2:218,162,841...218,166,962
JBrowse link
G CXCR4 C-X-C motif chemokine receptor 4 increases expression EXP Benzalkonium Compounds results in increased expression of CXCR4 mRNA CTD PMID:20713136 NCBI chr 2:136,114,349...136,118,149
Ensembl chr 2:136,114,349...136,119,177
JBrowse link
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 decreases expression
increases expression
EXP Benzalkonium Compounds results in decreased expression of CYP1A1 mRNA
Benzalkonium Compounds results in increased expression of CYP1A1 mRNA
CTD PMID:20713136 PMID:30806763 NCBI chr15:74,719,542...74,725,528
Ensembl chr15:74,719,542...74,725,536
JBrowse link
G CYP27A1 cytochrome P450 family 27 subfamily A member 1 decreases expression EXP Benzalkonium Compounds results in decreased expression of CYP27A1 mRNA CTD PMID:20713136 NCBI chr 2:218,782,147...218,815,293
Ensembl chr 2:218,781,749...218,815,293
JBrowse link
G CYP51A1 cytochrome P450 family 51 subfamily A member 1 increases expression ISO Benzalkonium Compounds results in increased expression of CYP51 mRNA CTD PMID:31199489 NCBI chr 7:92,112,153...92,134,803
Ensembl chr 7:92,084,987...92,134,803
JBrowse link
G DDIT3 DNA damage inducible transcript 3 increases expression EXP Benzalkonium Compounds results in increased expression of DDIT3 mRNA CTD PMID:37149095 NCBI chr12:57,516,588...57,520,517
Ensembl chr12:57,516,588...57,521,737
JBrowse link
G DHCR24 24-dehydrocholesterol reductase increases expression ISO Benzalkonium Compounds results in increased expression of DHCR24 mRNA CTD PMID:31199489 NCBI chr 1:54,849,627...54,887,195
Ensembl chr 1:54,849,627...54,887,195
JBrowse link
G DHCR7 7-dehydrocholesterol reductase decreases activity
increases expression
EXP
ISO
Benzalkonium Compounds results in decreased activity of DHCR7 protein
Benzalkonium Compounds results in increased expression of DHCR7 mRNA
CTD PMID:26919959 NCBI chr11:71,427,287...71,449,043
Ensembl chr11:71,428,193...71,452,868
JBrowse link
G DIO1 iodothyronine deiodinase 1 decreases activity EXP Benzalkonium Compounds results in decreased activity of DIO1 protein CTD PMID:30561685 NCBI chr 1:53,894,187...53,911,086
Ensembl chr 1:53,891,239...53,911,086
JBrowse link
G DIO2 iodothyronine deiodinase 2 decreases activity EXP Benzalkonium Compounds results in decreased activity of DIO2 protein CTD PMID:30561685 NCBI chr14:80,197,526...80,231,057
Ensembl chr14:80,197,526...80,387,757
JBrowse link
G DIO3 iodothyronine deiodinase 3 decreases activity EXP Benzalkonium Compounds results in decreased activity of DIO3 protein CTD PMID:30561685 NCBI chr14:101,561,495...101,563,452
Ensembl chr14:101,560,139...101,563,452
JBrowse link
G DLK1 delta like non-canonical Notch ligand 1 decreases expression ISO Benzalkonium Compounds results in decreased expression of DLK1 mRNA CTD PMID:31199489 NCBI chr14:100,726,892...100,738,224
Ensembl chr14:100,725,705...100,738,224
JBrowse link
G DUSP1 dual specificity phosphatase 1 increases expression EXP Benzalkonium Compounds results in increased expression of DUSP1 mRNA CTD PMID:30806763 NCBI chr 5:172,768,096...172,771,195
Ensembl chr 5:172,768,096...172,771,195
JBrowse link
G DUSP10 dual specificity phosphatase 10 increases expression EXP Benzalkonium Compounds results in increased expression of DUSP10 mRNA CTD PMID:37149095 NCBI chr 1:221,701,424...221,742,089
Ensembl chr 1:221,701,424...221,742,089
JBrowse link
G EBP EBP cholestenol delta-isomerase increases expression EXP Benzalkonium Compounds results in increased expression of EBP mRNA CTD PMID:26919959 NCBI chr  X:48,521,808...48,528,716
Ensembl chr  X:48,521,799...48,528,716
JBrowse link
G EGF epidermal growth factor decreases expression ISO Benzalkonium Compounds results in decreased expression of EGF mRNA CTD PMID:30171875 NCBI chr 4:109,912,883...110,013,766
Ensembl chr 4:109,912,883...110,013,766
JBrowse link
G EGR1 early growth response 1 increases expression EXP Benzalkonium Compounds results in increased expression of EGR1 mRNA CTD PMID:25377654 NCBI chr 5:138,465,479...138,469,303
Ensembl chr 5:138,465,479...138,469,303
JBrowse link
G ELF3 E74 like ETS transcription factor 3 increases expression ISO Benzalkonium Compounds results in increased expression of ELF3 mRNA CTD PMID:30171875 NCBI chr 1:202,010,587...202,017,183
Ensembl chr 1:202,007,945...202,017,183
JBrowse link
G ELOVL1 ELOVL fatty acid elongase 1 increases expression EXP Benzalkonium Compounds results in increased expression of ELOVL1 mRNA CTD PMID:29155129 NCBI chr 1:43,363,401...43,368,011
Ensembl chr 1:43,363,398...43,368,074
JBrowse link
G ELOVL6 ELOVL fatty acid elongase 6 increases expression ISO Benzalkonium Compounds results in increased expression of ELOVL6 mRNA CTD PMID:31199489 NCBI chr 4:110,045,846...110,199,202
Ensembl chr 4:110,045,846...110,199,199
JBrowse link
G ENDOU endonuclease, poly(U) specific increases expression ISO Benzalkonium Compounds results in increased expression of ENDOU mRNA CTD PMID:30171875 NCBI chr12:47,709,734...47,725,490
Ensembl chr12:47,709,734...47,725,567
JBrowse link
G ENO1 enolase 1 decreases expression ISO Benzalkonium Compounds results in decreased expression of ENO1 mRNA CTD PMID:31199489 NCBI chr 1:8,861,000...8,878,686
Ensembl chr 1:8,861,000...8,879,190
JBrowse link
G ETNK1 ethanolamine kinase 1 increases expression ISO Benzalkonium Compounds results in increased expression of ETNK1 mRNA CTD PMID:31199489 NCBI chr12:22,625,171...22,690,665
Ensembl chr12:22,625,075...22,690,665
JBrowse link
G EXO1 exonuclease 1 increases expression ISO Benzalkonium Compounds results in increased expression of EXO1 mRNA CTD PMID:30171875 NCBI chr 1:241,847,986...241,889,939
Ensembl chr 1:241,847,967...241,895,148
JBrowse link
G EZR ezrin increases expression EXP Benzalkonium Compounds results in increased expression of EZR mRNA; Benzalkonium Compounds results in increased expression of EZR protein CTD PMID:29893927 NCBI chr 6:158,765,748...158,819,368
Ensembl chr 6:158,765,741...158,819,368
JBrowse link
G FAM83A family with sequence similarity 83 member A increases expression ISO Benzalkonium Compounds results in increased expression of FAM83A mRNA CTD PMID:30171875 NCBI chr 8:123,179,047...123,210,079
Ensembl chr 8:123,178,960...123,210,079
JBrowse link
G FGF2 fibroblast growth factor 2 affects response to substance EXP FGF2 SNP affects the susceptibility to Benzalkonium Compounds CTD PMID:27206134 NCBI chr 4:122,826,682...122,898,236
Ensembl chr 4:122,826,682...122,898,236
JBrowse link
G FGR FGR proto-oncogene, Src family tyrosine kinase increases expression ISO Benzalkonium Compounds results in increased expression of FGR mRNA CTD PMID:30171875 NCBI chr 1:27,612,064...27,635,185
Ensembl chr 1:27,612,064...27,635,185
JBrowse link
G FLG filaggrin increases expression ISO Benzalkonium Compounds results in increased expression of FLG mRNA CTD PMID:30171875 NCBI chr 1:152,302,165...152,325,239
Ensembl chr 1:152,302,165...152,325,239
JBrowse link
G FOXC1 forkhead box C1 multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of FOXC1 mRNA CTD PMID:30171875 NCBI chr 6:1,609,915...1,613,897
Ensembl chr 6:1,609,915...1,613,897
JBrowse link
G FOXN1 forkhead box N1 multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of FOXN1 mRNA CTD PMID:30171875 NCBI chr17:28,506,348...28,538,900
Ensembl chr17:28,506,243...28,538,900
JBrowse link
G FOXP3 forkhead box P3 multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of FOXP3 mRNA CTD PMID:30171875 NCBI chr  X:49,250,438...49,264,710
Ensembl chr  X:49,250,438...49,264,800
JBrowse link
G GATA3 GATA binding protein 3 multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of GATA3 mRNA CTD PMID:30171875 NCBI chr10:8,045,333...8,075,198
Ensembl chr10:8,045,378...8,075,198
JBrowse link
G GCLC glutamate-cysteine ligase catalytic subunit increases expression EXP Benzalkonium Compounds results in increased expression of GCLC mRNA CTD PMID:30806763 NCBI chr 6:53,497,341...53,545,101
Ensembl chr 6:53,497,341...53,616,970
JBrowse link
G GCLM glutamate-cysteine ligase modifier subunit increases expression EXP Benzalkonium Compounds results in increased expression of GCLM mRNA CTD PMID:30806763 NCBI chr 1:93,885,199...93,909,430
Ensembl chr 1:93,885,199...93,909,456
JBrowse link
G GPX2 glutathione peroxidase 2 increases expression ISO Benzalkonium Compounds results in increased expression of GPX2 mRNA CTD PMID:30171875 NCBI chr14:64,939,158...64,942,745
Ensembl chr14:64,939,152...64,942,746
JBrowse link
G HBEGF heparin binding EGF like growth factor increases expression ISO Benzalkonium Compounds results in increased expression of HBEGF mRNA CTD PMID:30171875 NCBI chr 5:140,332,843...140,346,603
Ensembl chr 5:140,332,843...140,346,603
JBrowse link
G HCK HCK proto-oncogene, Src family tyrosine kinase multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of HCK mRNA CTD PMID:30171875 NCBI chr20:32,052,242...32,101,856
Ensembl chr20:32,052,197...32,101,856
JBrowse link
G HERPUD1 homocysteine inducible ER protein with ubiquitin like domain 1 increases expression EXP Benzalkonium Compounds results in increased expression of HERPUD1 mRNA CTD PMID:37149095 NCBI chr16:56,932,142...56,944,864
Ensembl chr16:56,932,142...56,944,864
JBrowse link
G HGF hepatocyte growth factor multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of HGF mRNA CTD PMID:30171875 NCBI chr 7:81,699,010...81,770,047
Ensembl chr 7:81,699,010...81,770,438
JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha increases expression ISO Benzalkonium Compounds results in increased expression of HIF1A mRNA CTD PMID:30171875 NCBI chr14:61,695,513...61,748,258
Ensembl chr14:61,695,513...61,748,259
JBrowse link
G HIF1A-AS3 HIF1A antisense RNA 3 decreases expression EXP Benzalkonium Compounds results in decreased expression of HIF1A-AS3 CTD PMID:37149095 NCBI chr14:61,715,558...61,751,097
Ensembl chr14:61,678,402...61,751,163
JBrowse link
G HLA-DOA major histocompatibility complex, class II, DO alpha affects response to substance EXP HLA-DOA SNP affects the susceptibility to Benzalkonium Compounds CTD PMID:27258892 NCBI chr 6:33,004,182...33,009,591
Ensembl chr 6:33,004,182...33,009,591
JBrowse link
G HLA-DOB major histocompatibility complex, class II, DO beta affects response to substance EXP HLA-DOB SNP affects the susceptibility to Benzalkonium Compounds CTD PMID:27258892 NCBI chr 6:32,812,763...32,817,002
Ensembl chr 6:32,812,763...32,820,466
JBrowse link
G HLA-DPA1 major histocompatibility complex, class II, DP alpha 1 affects response to substance EXP HLA-DPA1 SNP affects the susceptibility to Benzalkonium Compounds CTD PMID:27258892 NCBI chr 6:33,064,569...33,080,748
Ensembl chr 6:33,064,569...33,080,775
JBrowse link
G HLA-DPB1 major histocompatibility complex, class II, DP beta 1 affects response to substance EXP HLA-DPB1 SNP affects the susceptibility to Benzalkonium Compounds CTD PMID:27258892 NCBI chr 6:33,075,990...33,089,696
Ensembl chr 6:33,075,936...33,089,696
JBrowse link
G HLA-DQB2 major histocompatibility complex, class II, DQ beta 2 affects response to substance EXP HLA-DQB2 SNP affects the susceptibility to Benzalkonium Compounds CTD PMID:27258892 NCBI chr 6:32,756,098...32,763,532
Ensembl chr 6:32,756,098...32,763,532
JBrowse link
G HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase increases expression EXP
ISO
Benzalkonium Compounds results in increased expression of HMGCR mRNA CTD PMID:26919959 PMID:31199489 NCBI chr 5:75,336,529...75,362,116
Ensembl chr 5:75,336,329...75,364,001
JBrowse link
G HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 increases expression ISO Benzalkonium Compounds results in increased expression of HMGCS2 mRNA CTD PMID:31199489 NCBI chr 1:119,747,996...119,768,932
Ensembl chr 1:119,748,002...119,768,905
JBrowse link
G HMOX1 heme oxygenase 1 increases expression EXP Benzalkonium Compounds results in increased expression of HMOX1 mRNA CTD PMID:37149095 NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214
JBrowse link
G HOXA7 homeobox A7 decreases expression ISO Benzalkonium Compounds results in decreased expression of HOXA7 mRNA CTD PMID:30171875 NCBI chr 7:27,153,716...27,156,675
Ensembl chr 7:27,153,716...27,157,936
JBrowse link
G HSD17B7 hydroxysteroid 17-beta dehydrogenase 7 increases expression ISO Benzalkonium Compounds results in increased expression of HSD17B7 mRNA CTD PMID:31199489 NCBI chr 1:162,790,702...162,812,823
Ensembl chr 1:162,790,702...162,812,823
JBrowse link
G HSPA5 heat shock protein family A (Hsp70) member 5 decreases expression EXP Benzalkonium Compounds results in decreased expression of HSPA5 mRNA CTD PMID:28236482 NCBI chr 9:125,234,853...125,241,343
Ensembl chr 9:125,234,853...125,241,382
JBrowse link
G ICAM1 intercellular adhesion molecule 1 increases expression EXP Benzalkonium Compounds results in increased expression of ICAM1 mRNA; Benzalkonium Compounds results in increased expression of ICAM1 protein CTD PMID:21742781 PMID:30806763 NCBI chr19:10,271,120...10,286,615
Ensembl chr19:10,271,093...10,286,615
JBrowse link
G ID1 inhibitor of DNA binding 1 increases expression EXP Benzalkonium Compounds results in increased expression of ID1 mRNA CTD PMID:37149095 NCBI chr20:31,605,289...31,606,510
Ensembl chr20:31,573,014...31,606,515
JBrowse link
G IDI1 isopentenyl-diphosphate delta isomerase 1 increases expression ISO Benzalkonium Compounds results in increased expression of IDI1 mRNA CTD PMID:31199489 NCBI chr10:1,039,152...1,056,704
Ensembl chr10:1,039,152...1,049,119
JBrowse link
G IFNG interferon gamma increases expression ISO Benzalkonium Compounds results in increased expression of IFNG protein CTD PMID:30517752 NCBI chr12:68,154,768...68,159,740
Ensembl chr12:68,154,768...68,159,740
JBrowse link
G IGHA2 immunoglobulin heavy constant alpha 2 (A2m marker) multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of IGHA mRNA CTD PMID:30171875 NCBI chr14:105,586,937...105,588,394
Ensembl chr14:105,583,731...105,588,395
JBrowse link
G IGHG3 immunoglobulin heavy constant gamma 3 (G3m marker) increases expression ISO Benzalkonium Compounds results in increased expression of IGHG3 mRNA CTD PMID:30171875 NCBI chr14:105,765,914...105,771,405
Ensembl chr14:105,764,503...105,771,405
JBrowse link
G IGKV1D-27 immunoglobulin kappa variable 1D-27 (pseudogene) decreases expression EXP Benzalkonium Compounds results in decreased expression of IGKV1D-27 mRNA CTD PMID:25377654 NCBI chr 2:89,968,869...89,969,344
Ensembl chr 2:89,968,867...89,969,335
JBrowse link
G IGLL1 immunoglobulin lambda like polypeptide 1 decreases expression ISO Benzalkonium Compounds results in decreased expression of IGHD mRNA CTD PMID:30171875 NCBI chr22:23,573,125...23,580,290
Ensembl chr22:23,573,125...23,580,302
JBrowse link
G IL10 interleukin 10 multiple interactions
increases expression
EXP
ISO
Benzalkonium Compounds results in increased expression of and results in decreased secretion of IL10 protein
[IL6RA gene mutant form results in increased susceptibility to Benzalkonium Compounds] which results in decreased expression of IL10 protein
Benzalkonium Compounds results in increased expression of IL10 protein
CTD PMID:29953848 PMID:30517752 PMID:31158415 NCBI chr 1:206,767,602...206,772,494
Ensembl chr 1:206,767,602...206,774,541
JBrowse link
G IL13RA2 interleukin 13 receptor subunit alpha 2 increases expression ISO Benzalkonium Compounds results in increased expression of IL13RA2 mRNA CTD PMID:30171875 NCBI chr  X:115,003,982...115,017,616
Ensembl chr  X:115,003,975...115,019,977
JBrowse link
G IL15 interleukin 15 increases expression ISO Benzalkonium Compounds results in increased expression of IL15 protein CTD PMID:30517752 NCBI chr 4:141,636,583...141,733,987
Ensembl chr 4:141,636,583...141,733,987
JBrowse link
G IL17F interleukin 17F increases expression ISO Benzalkonium Compounds results in increased expression of IL17F mRNA CTD PMID:23445166 NCBI chr 6:52,236,681...52,245,689
Ensembl chr 6:52,236,681...52,245,689
JBrowse link
G IL18 interleukin 18 increases expression ISO
EXP
Benzalkonium Compounds results in increased expression of IL18 protein
Benzalkonium Compounds results in increased expression of IL18 mRNA
CTD PMID:30517752 PMID:30806763 NCBI chr11:112,143,260...112,164,094
Ensembl chr11:112,143,251...112,164,096
JBrowse link
G IL1A interleukin 1 alpha increases secretion
multiple interactions
increases expression
EXP
ISO
Benzalkonium Compounds results in increased secretion of IL1A protein
[IL6RA gene mutant form results in increased susceptibility to Benzalkonium Compounds] which results in increased expression of IL1A protein
Benzalkonium Compounds results in increased expression of IL1A protein
Benzalkonium Compounds results in increased expression of IL1A mRNA; Benzalkonium Compounds results in increased expression of IL1A protein
CTD PMID:8006454 PMID:12781210 PMID:25290854 PMID:30240708 PMID:30517752 More... NCBI chr 2:112,773,925...112,784,493
Ensembl chr 2:112,773,925...112,784,493
JBrowse link
G IL1B interleukin 1 beta increases expression
multiple interactions
EXP
ISO
Benzalkonium Compounds results in increased expression of IL1B protein
[IL6RA gene mutant form results in increased susceptibility to Benzalkonium Compounds] which results in increased expression of IL1B protein
CTD PMID:29953848 PMID:30517752 PMID:31158415 NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816
JBrowse link
G IL1F10 interleukin 1 family member 10 multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of IL1F10 mRNA CTD PMID:30171875 NCBI chr 2:113,067,970...113,075,843
Ensembl chr 2:113,067,970...113,075,843
JBrowse link
G IL22 interleukin 22 multiple interactions
increases expression
ISO [IL6RA gene mutant form results in increased susceptibility to Benzalkonium Compounds] which results in increased expression of IL22 protein
Benzalkonium Compounds results in increased expression of IL22 protein
CTD PMID:30517752 PMID:31158415 NCBI chr12:68,248,242...68,253,604
Ensembl chr12:68,248,242...68,253,604
JBrowse link
G IL23A interleukin 23 subunit alpha increases expression ISO Benzalkonium Compounds results in increased expression of IL23A mRNA CTD PMID:30171875 NCBI chr12:56,338,884...56,340,410
Ensembl chr12:56,334,174...56,340,410
JBrowse link
G IL24 interleukin 24 increases expression EXP Benzalkonium Compounds results in increased expression of IL24 mRNA CTD PMID:37149095 NCBI chr 1:206,897,443...206,904,139
Ensembl chr 1:206,897,443...206,904,139
JBrowse link
G IL27 interleukin 27 increases expression ISO Benzalkonium Compounds results in increased expression of IL27 protein CTD PMID:30517752 NCBI chr16:28,499,362...28,506,834
Ensembl chr16:28,499,362...28,512,051
JBrowse link
G IL3 interleukin 3 increases expression ISO Benzalkonium Compounds results in increased expression of IL3 protein CTD PMID:30517752 NCBI chr 5:132,060,655...132,063,204
Ensembl chr 5:132,060,655...132,063,204
JBrowse link
G IL31 interleukin 31 increases expression ISO Benzalkonium Compounds results in increased expression of IL31 protein CTD PMID:30517752 NCBI chr12:122,172,029...122,174,221
Ensembl chr12:122,172,029...122,174,221
JBrowse link
G IL31RA interleukin 31 receptor A decreases expression ISO Benzalkonium Compounds results in decreased expression of IL31RA mRNA CTD PMID:30171875 NCBI chr 5:55,839,789...55,922,850
Ensembl chr 5:55,851,357...55,922,854
JBrowse link
G IL34 interleukin 34 decreases expression ISO Benzalkonium Compounds results in decreased expression of IL34 mRNA CTD PMID:30171875 NCBI chr16:70,579,899...70,660,682
Ensembl chr16:70,579,895...70,660,682
JBrowse link
G IL36A interleukin 36 alpha increases expression ISO Benzalkonium Compounds results in increased expression of IL36A mRNA CTD PMID:30171875 NCBI chr 2:113,005,459...113,011,072
Ensembl chr 2:113,005,459...113,008,044
JBrowse link
G IL36B interleukin 36 beta increases expression ISO Benzalkonium Compounds results in increased expression of IL36B mRNA CTD PMID:30171875 NCBI chr 2:113,022,089...113,052,867
Ensembl chr 2:113,022,089...113,052,867
JBrowse link
G IL36G interleukin 36 gamma increases expression ISO Benzalkonium Compounds results in increased expression of IL36G mRNA CTD PMID:30171875 NCBI chr 2:112,978,006...112,985,658
Ensembl chr 2:112,973,203...112,985,658
JBrowse link
G IL4 interleukin 4 increases expression
multiple interactions
ISO Benzalkonium Compounds results in increased expression of IL4 protein
[IL6RA gene mutant form results in increased susceptibility to Benzalkonium Compounds] which results in decreased expression of IL4 protein
CTD PMID:30517752 PMID:31158415 NCBI chr 5:132,673,989...132,682,678
Ensembl chr 5:132,673,986...132,682,678
JBrowse link
G IL5 interleukin 5 increases expression ISO Benzalkonium Compounds results in increased expression of IL5 protein CTD PMID:30517752 NCBI chr 5:132,541,445...132,556,815
Ensembl chr 5:132,541,445...132,556,838
JBrowse link
G IL6 interleukin 6 increases secretion
affects response to substance
multiple interactions
increases expression
EXP
ISO
Benzalkonium Compounds results in increased secretion of IL6 protein
IL6 protein affects the susceptibility to Benzalkonium Compounds
[IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of ADRA2A mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of AGTR2 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of C1S2 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of C3 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of CD177 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of CD274 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of CTPS1 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of CXCL3 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of CXCL5 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of FOXC1 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of FOXN1 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of FOXP3 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of GATA3 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of GSDMA3 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of HCK mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of HGF mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of IGHA mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of IL1F10 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of KRT2 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of KRTAP14 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of KRTAP16-3 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of KRTAP19-2 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of KRTAP19-5 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of KRTAP19-9B mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of KRTAP6-1 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of KRTAP6-2 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of LTB mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of MMP25 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of MMP9 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of MRGPRA2B mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of MSX2 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of MYLK3 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of NRG2 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of PDCD1 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of PROKR2 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of PTX3 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of REG1 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of REG3G mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of RYR1 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of SAA3 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of SERPINB13 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of SIGLECE mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of SOX21 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of SRMS mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of ST14 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of TFAP2B mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of TNFRSF13C mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of TNFRSF26 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of TNFSF8 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of TSLP mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of VTCN1 mRNA; [IL6RA gene mutant form results in increased susceptibility to Benzalkonium Compounds] which results in increased expression of IL6 protein
Benzalkonium Compounds results in increased expression of IL6 mRNA; Benzalkonium Compounds results in increased expression of IL6 protein
Benzalkonium Compounds results in increased expression of and results in increased secretion of IL6 protein
CTD PMID:17763283 PMID:28214551 PMID:29953848 PMID:30171875 PMID:30517752 More... NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002
JBrowse link
G IL6R interleukin 6 receptor multiple interactions
increases response to substance
ISO [IL6RA gene mutant form results in increased susceptibility to Benzalkonium Compounds] which results in decreased expression of IL10 protein; [IL6RA gene mutant form results in increased susceptibility to Benzalkonium Compounds] which results in decreased expression of IL4 protein; [IL6RA gene mutant form results in increased susceptibility to Benzalkonium Compounds] which results in increased expression of CCL3 protein; [IL6RA gene mutant form results in increased susceptibility to Benzalkonium Compounds] which results in increased expression of CCL4 protein; [IL6RA gene mutant form results in increased susceptibility to Benzalkonium Compounds] which results in increased expression of CXCL10 protein; [IL6RA gene mutant form results in increased susceptibility to Benzalkonium Compounds] which results in increased expression of CXCL2 protein; [IL6RA gene mutant form results in increased susceptibility to Benzalkonium Compounds] which results in increased expression of IL1A protein; [IL6RA gene mutant form results in increased susceptibility to Benzalkonium Compounds] which results in increased expression of IL1B protein; [IL6RA gene mutant form results in increased susceptibility to Benzalkonium Compounds] which results in increased expression of IL22 protein; [IL6RA gene mutant form results in increased susceptibility to Benzalkonium Compounds] which results in increased expression of IL6 protein CTD PMID:31158415 NCBI chr 1:154,405,343...154,469,450
Ensembl chr 1:154,405,193...154,469,450
JBrowse link
G IL7R interleukin 7 receptor increases expression EXP Benzalkonium Compounds results in increased expression of IL7R mRNA CTD PMID:20713136 NCBI chr 5:35,856,891...35,879,603
Ensembl chr 5:35,852,695...35,879,603
JBrowse link
G INHBA inhibin subunit beta A increases expression ISO Benzalkonium Compounds results in increased expression of INHBA mRNA CTD PMID:30171875 NCBI chr 7:41,685,114...41,705,406
Ensembl chr 7:41,667,168...41,705,834
JBrowse link
G INSIG1 insulin induced gene 1 increases expression ISO Benzalkonium Compounds results in increased expression of INSIG1 mRNA CTD PMID:31199489 NCBI chr 7:155,297,878...155,310,235
Ensembl chr 7:155,297,776...155,310,235
JBrowse link
G ISL1 ISL LIM homeobox 1 decreases expression ISO Benzalkonium Compounds results in decreased expression of ISL1 mRNA CTD PMID:30171875 NCBI chr 5:51,383,448...51,394,730
Ensembl chr 5:51,383,448...51,394,730
JBrowse link
G IYD iodotyrosine deiodinase multiple interactions EXP Benzalkonium Compounds inhibits the reaction [IYD protein results in increased metabolism of Monoiodotyrosine] CTD PMID:33352258 NCBI chr 6:150,369,012...150,405,969
Ensembl chr 6:150,368,892...150,405,969
JBrowse link
G KCNH2 potassium voltage-gated channel subfamily H member 2 decreases activity EXP Benzalkonium Compounds results in decreased activity of KCNH2 protein CTD PMID:24052561 NCBI chr 7:150,944,961...150,978,321
Ensembl chr 7:150,944,961...150,978,321
JBrowse link
G KDM7A lysine demethylase 7A increases expression EXP Benzalkonium Compounds results in increased expression of KDM7A mRNA CTD PMID:37149095 NCBI chr 7:140,084,746...140,176,983
Ensembl chr 7:140,084,746...140,176,983
JBrowse link
G KDM8 lysine demethylase 8 decreases expression ISO Benzalkonium Compounds results in decreased expression of KDM8 mRNA CTD PMID:31199489 NCBI chr16:27,203,526...27,221,768
Ensembl chr16:27,203,508...27,221,768
JBrowse link
G KIR3DL2 killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 2 decreases expression EXP Benzalkonium Compounds results in decreased expression of KIR3DL2 mRNA CTD PMID:25377654 NCBI chr19:54,850,443...54,867,207
Ensembl chr19:54,850,443...54,867,209
JBrowse link
G KLF2 KLF transcription factor 2 increases expression EXP Benzalkonium Compounds results in increased expression of KLF2 mRNA CTD PMID:37149095 NCBI chr19:16,324,826...16,328,685
Ensembl chr19:16,324,826...16,328,685
JBrowse link
G KLK8 kallikrein related peptidase 8 increases expression ISO Benzalkonium Compounds results in increased expression of KLK8 mRNA CTD PMID:30171875 NCBI chr19:50,996,008...51,001,604
Ensembl chr19:50,996,007...51,002,711
JBrowse link
G KRT2 keratin 2 multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of KRT2 mRNA CTD PMID:30171875 NCBI chr12:52,644,558...52,652,211
Ensembl chr12:52,644,558...52,652,211
JBrowse link
G KRT6B keratin 6B increases expression ISO Benzalkonium Compounds results in increased expression of KRT6B mRNA CTD PMID:30171875 NCBI chr12:52,446,651...52,452,146
Ensembl chr12:52,446,651...52,452,146
JBrowse link
G KRTAP19-5 keratin associated protein 19-5 multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of KRTAP19-5 mRNA CTD PMID:30171875 NCBI chr21:30,501,657...30,502,141
Ensembl chr21:30,501,657...30,502,141
JBrowse link
G KRTAP19-6 keratin associated protein 19-6 multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of KRTAP16-3 mRNA CTD PMID:30171875 NCBI chr21:30,541,535...30,541,864
Ensembl chr21:30,541,535...30,541,864
JBrowse link
G KRTAP23-1 keratin associated protein 23-1 multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of KRTAP14 mRNA CTD PMID:30171875 NCBI chr21:30,348,399...30,348,606
Ensembl chr21:30,348,399...30,348,606
JBrowse link
G KRTAP6-1 keratin associated protein 6-1 multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of KRTAP6-1 mRNA CTD PMID:30171875 NCBI chr21:30,613,431...30,613,930
Ensembl chr21:30,613,431...30,613,930
JBrowse link
G KRTAP6-3 keratin associated protein 6-3 multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of KRTAP6-2 mRNA CTD PMID:30171875 NCBI chr21:30,592,440...30,593,055
Ensembl chr21:30,592,440...30,593,075
JBrowse link
G LCE3B late cornified envelope 3B increases expression ISO Benzalkonium Compounds results in increased expression of LCE3C mRNA CTD PMID:30171875 NCBI chr 1:152,613,811...152,614,098
Ensembl chr 1:152,613,811...152,614,098
JBrowse link
G LCE5A late cornified envelope 5A decreases expression ISO Benzalkonium Compounds results in decreased expression of LCE1M mRNA CTD PMID:30171875 NCBI chr 1:152,510,803...152,512,177
Ensembl chr 1:152,510,803...152,512,177
JBrowse link
G LDHA lactate dehydrogenase A decreases expression ISO Benzalkonium Compounds results in decreased expression of LDHA mRNA CTD PMID:31199489 NCBI chr11:18,394,563...18,408,425
Ensembl chr11:18,394,560...18,408,425
JBrowse link
G LDLR low density lipoprotein receptor increases expression ISO Benzalkonium Compounds results in increased expression of LDLR mRNA CTD PMID:31199489 NCBI chr19:11,089,463...11,133,820
Ensembl chr19:11,089,418...11,133,820
JBrowse link
G LIF LIF interleukin 6 family cytokine increases expression ISO Benzalkonium Compounds results in increased expression of LIF protein CTD PMID:30517752 NCBI chr22:30,240,453...30,246,759
Ensembl chr22:30,240,453...30,246,759
JBrowse link
G LOXL1 lysyl oxidase like 1 decreases expression ISO Benzalkonium Compounds results in decreased expression of LOXL1 mRNA CTD PMID:31199489 NCBI chr15:73,926,462...73,952,136
Ensembl chr15:73,925,989...73,952,137
JBrowse link
G LST1 leukocyte specific transcript 1 increases expression ISO Benzalkonium Compounds results in increased expression of LST1 mRNA CTD PMID:30171875 NCBI chr 6:31,586,277...31,588,909
Ensembl chr 6:31,586,124...31,588,909
JBrowse link
G LTB lymphotoxin beta multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of LTB mRNA CTD PMID:30171875 NCBI chr 6:31,580,558...31,582,425
Ensembl chr 6:31,580,525...31,582,522
JBrowse link
G MAPK14 mitogen-activated protein kinase 14 increases phosphorylation EXP Benzalkonium Compounds results in increased phosphorylation of MAPK14 protein CTD PMID:15737199 NCBI chr 6:36,027,808...36,124,214
Ensembl chr 6:36,027,752...36,122,511
JBrowse link
G MESP2 mesoderm posterior bHLH transcription factor 2 decreases expression ISO Benzalkonium Compounds results in decreased expression of MESP2 mRNA CTD PMID:30171875 NCBI chr15:89,776,332...89,778,754
Ensembl chr15:89,760,591...89,778,754
JBrowse link
G MIF macrophage migration inhibitory factor increases secretion EXP Benzalkonium Compounds results in increased secretion of MIF protein CTD PMID:31707104 NCBI chr22:23,894,383...23,895,223
Ensembl chr22:23,894,383...23,895,227
JBrowse link
G MIR1296 microRNA 1296 increases expression EXP Benzalkonium Compounds results in increased expression of MIR1296 mRNA CTD PMID:25377654 NCBI chr10:63,372,957...63,373,048
Ensembl chr10:63,372,957...63,373,048
JBrowse link
G MIR4279 microRNA 4279 increases expression EXP Benzalkonium Compounds results in increased expression of MIR4279 CTD PMID:37149095 NCBI chr 5:31,936,102...31,936,159
Ensembl chr 5:31,936,102...31,936,159
JBrowse link
G MIR548AC microRNA 548ac increases expression EXP Benzalkonium Compounds results in increased expression of MIR548AC mRNA CTD PMID:25377654 NCBI chr 1:116,560,024...116,560,111
Ensembl chr 1:116,560,024...116,560,111
JBrowse link
G MIR548C microRNA 548c increases expression EXP Benzalkonium Compounds results in increased expression of MIR548C CTD PMID:37149095 NCBI chr12:64,622,509...64,622,605
Ensembl chr12:64,622,509...64,622,605
JBrowse link
G MIR635 microRNA 635 increases expression EXP Benzalkonium Compounds results in increased expression of MIR635 CTD PMID:37149095 NCBI chr17:68,424,451...68,424,548
Ensembl chr17:68,424,451...68,424,548
JBrowse link
G MIR891A microRNA 891a decreases expression EXP Benzalkonium Compounds results in decreased expression of MIR891A CTD PMID:37149095 NCBI chr  X:146,027,794...146,027,872
Ensembl chr  X:146,027,794...146,027,872
JBrowse link
G MMP10 matrix metallopeptidase 10 increases expression EXP Benzalkonium Compounds results in increased expression of MMP10 mRNA CTD PMID:30806763 NCBI chr11:102,770,502...102,780,628
Ensembl chr11:102,770,502...102,780,628
JBrowse link
G MMP12 matrix metallopeptidase 12 increases expression ISO Benzalkonium Compounds results in increased expression of MMP12 mRNA CTD PMID:30171875 NCBI chr11:102,862,736...102,874,982
Ensembl chr11:102,862,736...102,874,982
JBrowse link
G MMP2 matrix metallopeptidase 2 increases activity ISO Benzalkonium Compounds results in increased activity of MMP2 protein CTD PMID:21058936 NCBI chr16:55,478,830...55,506,691
Ensembl chr16:55,389,700...55,506,691
JBrowse link
G MMP25 matrix metallopeptidase 25 multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of MMP25 mRNA CTD PMID:30171875 NCBI chr16:3,046,561...3,060,726
Ensembl chr16:3,046,062...3,060,729
JBrowse link
G MMP9 matrix metallopeptidase 9 multiple interactions
increases activity
ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of MMP9 mRNA
Benzalkonium Compounds results in increased activity of MMP9 protein
CTD PMID:21058936 PMID:30171875 NCBI chr20:46,008,908...46,016,561
Ensembl chr20:46,008,908...46,016,561
JBrowse link
G MSMO1 methylsterol monooxygenase 1 increases expression ISO Benzalkonium Compounds results in increased expression of MSMO1 mRNA CTD PMID:31199489 NCBI chr 4:165,327,669...165,343,164
Ensembl chr 4:165,327,667...165,343,164
JBrowse link
G MSX2 msh homeobox 2 multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of MSX2 mRNA CTD PMID:30171875 NCBI chr 5:174,724,582...174,730,896
Ensembl chr 5:174,724,582...174,730,896
JBrowse link
G MT2A metallothionein 2A decreases expression ISO Benzalkonium Compounds results in decreased expression of MT2 mRNA CTD PMID:31199489 NCBI chr16:56,608,584...56,609,497
Ensembl chr16:56,608,584...56,609,497
JBrowse link
G MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase decreases expression ISO Benzalkonium Compounds results in decreased expression of MTHFD2 mRNA CTD PMID:31199489 NCBI chr 2:74,198,615...74,217,565
Ensembl chr 2:74,186,172...74,217,565
JBrowse link
G MYLK3 myosin light chain kinase 3 multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of MYLK3 mRNA CTD PMID:30171875 NCBI chr16:46,702,282...46,763,246
Ensembl chr16:46,702,282...46,790,407
JBrowse link
G NDUFA4 NDUFA4 mitochondrial complex associated decreases expression ISO Benzalkonium Compounds results in decreased expression of NDUFA4 mRNA CTD PMID:31199489 NCBI chr 7:10,931,943...10,940,153
Ensembl chr 7:10,931,943...10,940,153
JBrowse link
G NR4A2 nuclear receptor subfamily 4 group A member 2 increases expression EXP Benzalkonium Compounds results in increased expression of NR4A2 mRNA CTD PMID:25377654 NCBI chr 2:156,324,437...156,332,721
Ensembl chr 2:156,324,437...156,342,348
JBrowse link
G NRG2 neuregulin 2 multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of NRG2 mRNA CTD PMID:30171875 NCBI chr 5:139,846,781...140,043,299
Ensembl chr 5:139,846,779...140,043,299
JBrowse link
G NTRK3 neurotrophic receptor tyrosine kinase 3 affects response to substance EXP NTRK3 SNP affects the susceptibility to Benzalkonium Compounds CTD PMID:27206134 NCBI chr15:87,859,751...88,256,739
Ensembl chr15:87,859,751...88,256,791
JBrowse link
G OCLN occludin decreases expression ISO Benzalkonium Compounds results in decreased expression of OCLN protein CTD PMID:29514330 NCBI chr 5:69,492,547...69,558,104
Ensembl chr 5:69,492,292...69,558,104
JBrowse link
G ODC1 ornithine decarboxylase 1 decreases expression ISO Benzalkonium Compounds results in decreased expression of ODC1 mRNA CTD PMID:31199489 NCBI chr 2:10,439,968...10,448,327
Ensembl chr 2:10,439,968...10,448,327
JBrowse link
G OLR1 oxidized low density lipoprotein receptor 1 increases expression ISO Benzalkonium Compounds results in increased expression of OLR1 mRNA CTD PMID:30171875 NCBI chr12:10,158,301...10,176,266
Ensembl chr12:10,158,301...10,172,138
JBrowse link
G ORM1 orosomucoid 1 decreases expression ISO Benzalkonium Compounds results in decreased expression of ORM1 mRNA CTD PMID:30171875 NCBI chr 9:114,323,098...114,326,479
Ensembl chr 9:114,323,098...114,326,479
JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 increases cleavage
multiple interactions
EXP Benzalkonium Compounds analog results in increased cleavage of PARP1 protein
benzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketone inhibits the reaction [Benzalkonium Compounds analog results in increased cleavage of PARP1 protein]
CTD PMID:31982400 NCBI chr 1:226,360,691...226,408,093
Ensembl chr 1:226,360,210...226,408,154
JBrowse link
G PBK PDZ binding kinase increases expression ISO Benzalkonium Compounds results in increased expression of PBK mRNA CTD PMID:30171875 NCBI chr 8:27,809,624...27,837,817
Ensembl chr 8:27,809,624...27,838,082
JBrowse link
G PCSK9 proprotein convertase subtilisin/kexin type 9 decreases expression ISO Benzalkonium Compounds results in decreased expression of PCSK9 mRNA CTD PMID:31199489 NCBI chr 1:55,039,548...55,064,852
Ensembl chr 1:55,039,445...55,064,852
JBrowse link
G PDCD1 programmed cell death 1 multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of PDCD1 mRNA CTD PMID:30171875 NCBI chr 2:241,849,884...241,858,894
Ensembl chr 2:241,849,884...241,858,894
JBrowse link
G PFDN6 prefoldin subunit 6 affects response to substance EXP PFDN6 SNP affects the susceptibility to Benzalkonium Compounds CTD PMID:27258892 NCBI chr 6:33,289,197...33,290,934
Ensembl chr 6:33,289,302...33,298,401
JBrowse link
G PGLYRP3 peptidoglycan recognition protein 3 increases expression ISO Benzalkonium Compounds results in increased expression of PGLYRP3 mRNA CTD PMID:30171875 NCBI chr 1:153,297,116...153,312,952
Ensembl chr 1:153,297,116...153,312,952
JBrowse link
G PGP phosphoglycolate phosphatase increases expression ISO Benzalkonium Compounds results in increased expression of PGP mRNA CTD PMID:31199489 NCBI chr16:2,211,593...2,214,840
Ensembl chr16:2,211,593...2,214,840
JBrowse link
G PLA2G5 phospholipase A2 group V decreases expression ISO Benzalkonium Compounds results in decreased expression of PLA2G5 mRNA CTD PMID:30171875 NCBI chr 1:20,028,408...20,091,911
Ensembl chr 1:20,028,179...20,091,911
JBrowse link
G PLCXD3 phosphatidylinositol specific phospholipase C X domain containing 3 increases expression ISO Benzalkonium Compounds results in increased expression of PLCXD3 mRNA CTD PMID:31199489 NCBI chr 5:41,306,952...41,510,601
Ensembl chr 5:41,306,952...41,510,601
JBrowse link
G PLK2 polo like kinase 2 decreases expression EXP Benzalkonium Compounds results in decreased expression of PLK2 mRNA CTD PMID:37149095 NCBI chr 5:58,453,982...58,460,086
Ensembl chr 5:58,453,982...58,460,139
JBrowse link
G PNPLA2 patatin like phospholipase domain containing 2 decreases expression ISO Benzalkonium Compounds results in decreased expression of PNPLA2 mRNA CTD PMID:31199489 NCBI chr11:818,914...825,573
Ensembl chr11:818,914...825,573
JBrowse link
G POLR1D RNA polymerase I and III subunit D decreases expression ISO Benzalkonium Compounds results in decreased expression of POLR1D mRNA CTD PMID:31199489 NCBI chr13:27,620,743...27,667,411
Ensembl chr13:27,620,742...27,744,237
JBrowse link
G PPARA peroxisome proliferator activated receptor alpha decreases expression ISO Benzalkonium Compounds results in decreased expression of PPARA mRNA CTD PMID:31199489 NCBI chr22:46,150,526...46,243,756
Ensembl chr22:46,150,521...46,243,755
JBrowse link
G PRKAA2 protein kinase AMP-activated catalytic subunit alpha 2 increases expression ISO Benzalkonium Compounds results in increased expression of PRKAA2 mRNA CTD PMID:31199489 NCBI chr 1:56,645,314...56,715,335
Ensembl chr 1:56,645,314...56,715,335
JBrowse link
G PRKAG2 protein kinase AMP-activated non-catalytic subunit gamma 2 increases expression ISO Benzalkonium Compounds results in increased expression of PRKAG2 mRNA CTD PMID:31199489 NCBI chr 7:151,556,127...151,877,115
Ensembl chr 7:151,556,124...151,877,214
JBrowse link
G PROKR2 prokineticin receptor 2 multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of PROKR2 mRNA CTD PMID:30171875 NCBI chr20:5,299,218...5,316,954
Ensembl chr20:5,299,218...5,316,954
JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 increases expression EXP Benzalkonium Compounds results in increased expression of PTGS2 mRNA CTD PMID:30806763 NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922
JBrowse link
G PTX3 pentraxin 3 multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of PTX3 mRNA CTD PMID:30171875 NCBI chr 3:157,436,850...157,443,633
Ensembl chr 3:157,436,850...157,443,633
JBrowse link
G REG1A regenerating family member 1 alpha multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of REG1 mRNA CTD PMID:30171875 NCBI chr 2:79,120,488...79,123,409
Ensembl chr 2:79,120,362...79,123,409
JBrowse link
G REG3G regenerating family member 3 gamma multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of REG3G mRNA CTD PMID:30171875 NCBI chr 2:79,025,702...79,028,501
Ensembl chr 2:79,025,686...79,028,505
JBrowse link
G RGL2 ral guanine nucleotide dissociation stimulator like 2 affects response to substance EXP RGL2 SNP affects the susceptibility to Benzalkonium Compounds CTD PMID:27258892 NCBI chr 6:33,291,654...33,301,612
Ensembl chr 6:33,291,654...33,298,942
JBrowse link
G RNU2-63P RNA, U2 small nuclear 63, pseudogene decreases expression EXP Benzalkonium Compounds results in decreased expression of RNU2-63P CTD PMID:37149095 NCBI chr 2:88,016,354...88,016,547
Ensembl chr 2:88,016,354...88,016,547
JBrowse link
G RNU6-454P RNA, U6 small nuclear 454, pseudogene decreases expression EXP Benzalkonium Compounds results in decreased expression of RNU6-454P CTD PMID:37149095 NCBI chr 3:15,339,749...15,339,850
Ensembl chr 3:15,339,749...15,339,855
JBrowse link
G RNU6-643P RNA, U6 small nuclear 643, pseudogene decreases expression EXP Benzalkonium Compounds results in decreased expression of RNU6-643P CTD PMID:37149095 NCBI chr 6:41,302,466...41,302,572
Ensembl chr 6:41,302,466...41,302,572
JBrowse link
G RPS18 ribosomal protein S18 affects response to substance EXP RPS18 SNP affects the susceptibility to Benzalkonium Compounds CTD PMID:27258892 NCBI chr 6:33,272,075...33,276,511
Ensembl chr 6:33,272,075...33,276,511
JBrowse link
G RYR1 ryanodine receptor 1 multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of RYR1 mRNA CTD PMID:30171875 NCBI chr19:38,433,691...38,587,564
Ensembl chr19:38,433,691...38,595,273
JBrowse link
G SAA3P serum amyloid A3, pseudogene multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of SAA3 mRNA CTD PMID:30171875 NCBI chr11:18,112,472...18,116,132
Ensembl chr11:18,112,472...18,116,132
Ensembl chr11:18,112,472...18,116,132
JBrowse link
G SCD stearoyl-CoA desaturase increases expression EXP Benzalkonium Compounds results in increased expression of SCD mRNA CTD PMID:29155129 NCBI chr10:100,347,233...100,364,826
Ensembl chr10:100,347,233...100,364,826
JBrowse link
G SDIM1 stress responsive DNAJB4 interacting membrane protein 1 increases expression EXP Benzalkonium Compounds results in increased expression of SDIM1 mRNA CTD PMID:37149095
G SERPINB13 serpin family B member 13 multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of SERPINB13 mRNA CTD PMID:30171875 NCBI chr18:63,587,343...63,599,192
Ensembl chr18:63,586,989...63,604,639
JBrowse link
G SERPINE1 serpin family E member 1 increases expression ISO Benzalkonium Compounds results in increased expression of SERPINE1 mRNA CTD PMID:30171875 NCBI chr 7:101,127,104...101,139,247
Ensembl chr 7:101,127,104...101,139,247
JBrowse link
G SESN2 sestrin 2 decreases expression ISO Benzalkonium Compounds results in decreased expression of SESN2 mRNA CTD PMID:31199489 NCBI chr 1:28,259,518...28,282,491
Ensembl chr 1:28,259,518...28,282,491
JBrowse link
G SFN stratifin increases expression ISO Benzalkonium Compounds results in increased expression of SFN mRNA CTD PMID:30171875 NCBI chr 1:26,863,149...26,864,456
Ensembl chr 1:26,863,149...26,864,456
JBrowse link
G SFRP4 secreted frizzled related protein 4 decreases expression ISO Benzalkonium Compounds results in decreased expression of SFRP4 mRNA CTD PMID:30171875 NCBI chr 7:37,905,932...37,916,817
Ensembl chr 7:37,905,932...38,025,695
JBrowse link
G SIGLEC9 sialic acid binding Ig like lectin 9 multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of SIGLECE mRNA CTD PMID:30171875 NCBI chr19:51,119,778...51,136,263
Ensembl chr19:51,124,906...51,136,651
JBrowse link
G SLC16A1 solute carrier family 16 member 1 increases expression ISO Benzalkonium Compounds results in increased expression of SLC16A1 mRNA CTD PMID:31199489 NCBI chr 1:112,911,847...112,956,196
Ensembl chr 1:112,911,847...112,957,593
JBrowse link
G SLC7A11 solute carrier family 7 member 11 increases expression EXP Benzalkonium Compounds results in increased expression of SLC7A11 mRNA CTD PMID:30806763 PMID:37149095 NCBI chr 4:138,164,097...138,312,671
Ensembl chr 4:138,164,097...138,242,349
JBrowse link
G SNORA38 small nucleolar RNA, H/ACA box 38 decreases expression EXP Benzalkonium Compounds results in decreased expression of SNORA38 CTD PMID:37149095 NCBI chr 6:31,623,079...31,623,210
Ensembl chr 6:31,623,079...31,623,210
JBrowse link
G SNORA71D small nucleolar RNA, H/ACA box 71D decreases expression EXP Benzalkonium Compounds results in decreased expression of SNORA71D mRNA CTD PMID:25377654 NCBI chr20:38,433,862...38,433,999
Ensembl chr20:38,433,865...38,433,998
JBrowse link
G SNORD115-45 small nucleolar RNA, C/D box 115-45 increases expression EXP Benzalkonium Compounds results in increased expression of SNORD115-45 CTD PMID:37149095 NCBI chr15:25,264,527...25,264,579
Ensembl chr15:25,264,510...25,264,590
JBrowse link
G SOX21 SRY-box transcription factor 21 multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of SOX21 mRNA CTD PMID:30171875 NCBI chr13:94,709,622...94,712,545
Ensembl chr13:94,709,622...94,712,545
JBrowse link
G SPRR1A small proline rich protein 1A increases expression ISO Benzalkonium Compounds results in increased expression of SPRR1A mRNA CTD PMID:30171875 NCBI chr 1:152,984,081...152,985,814
Ensembl chr 1:152,984,081...152,985,814
JBrowse link
G SPRR1B small proline rich protein 1B increases expression ISO Benzalkonium Compounds results in increased expression of SPRR1B mRNA CTD PMID:30171875 NCBI chr 1:153,031,203...153,032,900
Ensembl chr 1:153,031,203...153,032,900
JBrowse link
G SPRR2A small proline rich protein 2A increases expression ISO Benzalkonium Compounds results in increased expression of SPRR2H mRNA CTD PMID:30171875 NCBI chr 1:153,056,120...153,057,512
Ensembl chr 1:153,056,120...153,057,512
JBrowse link
G SPRR2B small proline rich protein 2B increases expression ISO Benzalkonium Compounds results in increased expression of SPRR2B mRNA CTD PMID:30171875 NCBI chr 1:153,070,226...153,087,799
Ensembl chr 1:153,070,226...153,071,611
JBrowse link
G SPRR2F small proline rich protein 2F increases expression ISO Benzalkonium Compounds results in increased expression of SPRR2F mRNA CTD PMID:30171875 NCBI chr 1:153,112,121...153,119,468
Ensembl chr 1:153,112,121...153,113,516
JBrowse link
G SQLE squalene epoxidase increases expression ISO Benzalkonium Compounds results in increased expression of SQLE mRNA CTD PMID:31199489 NCBI chr 8:124,998,505...125,022,283
Ensembl chr 8:124,998,497...125,022,283
JBrowse link
G SREBF2 sterol regulatory element binding transcription factor 2 increases expression EXP Benzalkonium Compounds results in increased expression of SREBF2 mRNA CTD PMID:26919959 NCBI chr22:41,833,105...41,907,305
Ensembl chr22:41,833,105...41,907,306
JBrowse link
G SRMS src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of SRMS mRNA CTD PMID:30171875 NCBI chr20:63,538,489...63,547,749
Ensembl chr20:63,538,489...63,547,749
JBrowse link
G ST14 ST14 transmembrane serine protease matriptase multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of ST14 mRNA CTD PMID:30171875 NCBI chr11:130,159,782...130,210,362
Ensembl chr11:130,159,782...130,210,362
JBrowse link
G TAPBP TAP binding protein affects response to substance EXP TAPBP SNP affects the susceptibility to Benzalkonium Compounds CTD PMID:27258892 NCBI chr 6:33,299,694...33,314,078
Ensembl chr 6:33,299,694...33,314,284
JBrowse link
G TFAP2B transcription factor AP-2 beta multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of TFAP2B mRNA CTD PMID:30171875 NCBI chr 6:50,818,355...50,847,619
Ensembl chr 6:50,818,723...50,847,619
JBrowse link
G TGFB1 transforming growth factor beta 1 increases expression ISO Benzalkonium Compounds results in increased expression of TGFB1 protein CTD PMID:30517752 NCBI chr19:41,330,323...41,353,922
Ensembl chr19:41,301,587...41,353,922
JBrowse link
G TGM3 transglutaminase 3 increases expression ISO Benzalkonium Compounds results in increased expression of TGM3 mRNA CTD PMID:30171875 NCBI chr20:2,296,001...2,341,079
Ensembl chr20:2,296,001...2,341,079
JBrowse link
G TGM7 transglutaminase 7 decreases expression ISO Benzalkonium Compounds results in decreased expression of TGM7 mRNA CTD PMID:30171875 NCBI chr15:43,276,271...43,302,255
Ensembl chr15:43,276,271...43,302,255
JBrowse link
G THBS1 thrombospondin 1 increases expression ISO Benzalkonium Compounds results in increased expression of THBS1 mRNA CTD PMID:30171875 NCBI chr15:39,581,079...39,599,466
Ensembl chr15:39,581,079...39,599,466
JBrowse link
G TLR1 toll like receptor 1 increases expression ISO Benzalkonium Compounds results in increased expression of TLR1 mRNA CTD PMID:30171875 NCBI chr 4:38,787,569...38,805,644
Ensembl chr 4:38,787,555...38,856,817
JBrowse link
G TLR4 toll like receptor 4 increases activity ISO Benzalkonium Compounds results in increased activity of TLR4 protein CTD PMID:29514330 NCBI chr 9:117,704,403...117,724,735
Ensembl chr 9:117,704,175...117,724,735
JBrowse link
G TMPRSS11B transmembrane serine protease 11B increases expression ISO Benzalkonium Compounds results in increased expression of TMPRSS11B mRNA CTD PMID:30171875 NCBI chr 4:68,226,653...68,245,694
Ensembl chr 4:68,226,653...68,245,694
JBrowse link
G TNF tumor necrosis factor decreases secretion
increases expression
EXP
ISO
Benzalkonium Compounds results in decreased secretion of TNF protein
Benzalkonium Compounds results in increased expression of TNF mRNA; Benzalkonium Compounds results in increased expression of TNF protein
CTD PMID:29953848 PMID:30171875 PMID:30517752 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336
JBrowse link
G TNFAIP6 TNF alpha induced protein 6 increases expression ISO Benzalkonium Compounds results in increased expression of TNFAIP6 mRNA CTD PMID:30171875 NCBI chr 2:151,357,592...151,381,340
Ensembl chr 2:151,357,592...151,380,046
JBrowse link
G TNFRSF13C TNF receptor superfamily member 13C multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of TNFRSF13C mRNA CTD PMID:30171875 NCBI chr22:41,922,032...41,926,806
Ensembl chr22:41,922,032...41,926,806
JBrowse link
G TNFRSF9 TNF receptor superfamily member 9 increases expression ISO Benzalkonium Compounds results in increased expression of TNFRSF9 mRNA CTD PMID:30171875 NCBI chr 1:7,915,871...7,940,839
Ensembl chr 1:7,915,871...7,943,165
JBrowse link
G TNFSF8 TNF superfamily member 8 multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of TNFSF8 mRNA CTD PMID:30171875 NCBI chr 9:114,893,343...114,930,595
Ensembl chr 9:114,893,343...114,930,595
JBrowse link
G TP53 tumor protein p53 decreases expression EXP Benzalkonium Compounds results in decreased expression of TP53 mRNA CTD PMID:28236482 NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,546
JBrowse link
G TPI1 triosephosphate isomerase 1 decreases expression ISO Benzalkonium Compounds results in decreased expression of TPI1 mRNA CTD PMID:31199489 NCBI chr12:6,867,420...6,870,948
Ensembl chr12:6,867,119...6,870,948
JBrowse link
G TRDC T cell receptor delta constant decreases expression ISO Benzalkonium Compounds results in decreased expression of TRDC mRNA CTD PMID:30171875 NCBI chr14:22,462,932...22,466,577
Ensembl chr14:22,462,932...22,465,787
JBrowse link
G TRDV2 T cell receptor delta variable 2 decreases expression ISO Benzalkonium Compounds results in decreased expression of TRDV4 mRNA CTD PMID:30171875 NCBI chr14:22,422,546...22,423,042
Ensembl chr14:22,422,371...22,423,042
JBrowse link
G TREM2 triggering receptor expressed on myeloid cells 2 increases expression ISO Benzalkonium Compounds results in increased expression of TREM2 mRNA CTD PMID:30171875 NCBI chr 6:41,158,508...41,163,116
Ensembl chr 6:41,158,506...41,163,186
JBrowse link
G TRIB3 tribbles pseudokinase 3 increases expression EXP Benzalkonium Compounds results in increased expression of TRIB3 mRNA CTD PMID:37149095 NCBI chr20:380,760...397,559
Ensembl chr20:362,835...397,559
JBrowse link
G TSLP thymic stromal lymphopoietin multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of TSLP mRNA CTD PMID:30171875 NCBI chr 5:111,070,062...111,078,026
Ensembl chr 5:111,070,062...111,078,026
JBrowse link
G ULBP1 UL16 binding protein 1 increases expression EXP Benzalkonium Compounds results in increased expression of ULBP1 mRNA CTD PMID:37149095 NCBI chr 6:149,963,943...149,973,715
Ensembl chr 6:149,963,943...149,973,715
JBrowse link
G UPK3B uroplakin 3B decreases expression ISO Benzalkonium Compounds results in decreased expression of UPK3B mRNA CTD PMID:30171875 NCBI chr 7:76,510,552...76,516,522
Ensembl chr 7:76,510,525...76,516,522
JBrowse link
G UQCRQ ubiquinol-cytochrome c reductase complex III subunit VII decreases expression ISO Benzalkonium Compounds results in decreased expression of UQCRQ mRNA CTD PMID:31199489 NCBI chr 5:132,866,642...132,868,847
Ensembl chr 5:132,866,630...132,868,847
JBrowse link
G VEGFD vascular endothelial growth factor D increases expression EXP Benzalkonium Compounds results in increased expression of VEGFD mRNA CTD PMID:20146380 NCBI chr  X:15,345,596...15,384,413
Ensembl chr  X:15,345,596...15,384,413
JBrowse link
G VTCN1 V-set domain containing T cell activation inhibitor 1 multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of VTCN1 mRNA CTD PMID:30171875 NCBI chr 1:117,143,587...117,210,927
Ensembl chr 1:117,143,587...117,210,960
JBrowse link
G WDR46 WD repeat domain 46 affects response to substance EXP WDR46 SNP affects the susceptibility to Benzalkonium Compounds CTD PMID:27258892 NCBI chr 6:33,279,108...33,289,239
Ensembl chr 6:33,279,108...33,289,247
JBrowse link
G XBP1 X-box binding protein 1 decreases expression EXP Benzalkonium Compounds results in decreased expression of XBP1 mRNA alternative form CTD PMID:28236482 NCBI chr22:28,794,560...28,800,569
Ensembl chr22:28,794,555...28,800,597
JBrowse link
G XCL1 X-C motif chemokine ligand 1 decreases expression ISO Benzalkonium Compounds results in decreased expression of XCL1 mRNA CTD PMID:30171875 NCBI chr 1:168,576,605...168,582,069
Ensembl chr 1:168,576,605...168,582,069
JBrowse link
butylscopolamine bromide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SLC22A2 solute carrier family 22 member 2 multiple interactions EXP Butylscopolammonium Bromide inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr 6:160,216,755...160,258,821
Ensembl chr 6:160,171,061...160,277,638
JBrowse link
chlormequat chloride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCD1 ATP binding cassette subfamily D member 1 increases expression ISO Chlormequat results in increased expression of ABCD1 protein CTD PMID:34958886 NCBI chr  X:153,724,856...153,744,755
Ensembl chr  X:153,724,856...153,744,755
JBrowse link
G ADARB1 adenosine deaminase RNA specific B1 decreases expression ISO Chlormequat results in decreased expression of ADARB1 protein CTD PMID:34958886 NCBI chr21:45,074,578...45,226,563
Ensembl chr21:45,073,853...45,226,560
JBrowse link
G AGTRAP angiotensin II receptor associated protein increases expression ISO Chlormequat results in increased expression of AGTRAP protein CTD PMID:34958886 NCBI chr 1:11,736,136...11,750,769
Ensembl chr 1:11,736,084...11,754,802
JBrowse link
G AHR aryl hydrocarbon receptor multiple interactions EXP Chlormequat promotes the reaction [Tetrachlorodibenzodioxin results in increased activity of AHR protein] CTD PMID:25684042 NCBI chr 7:17,298,652...17,346,147
Ensembl chr 7:16,916,359...17,346,152
JBrowse link
G ALG12 ALG12 alpha-1,6-mannosyltransferase decreases expression ISO Chlormequat results in decreased expression of ALG12 protein CTD PMID:34958886 NCBI chr22:49,859,311...49,918,438
Ensembl chr22:49,900,229...49,918,438
JBrowse link
G ALG14 ALG14 UDP-N-acetylglucosaminyltransferase subunit decreases expression ISO Chlormequat results in decreased expression of ALG14 protein CTD PMID:34958886 NCBI chr 1:94,974,405...95,072,951
Ensembl chr 1:94,974,405...95,072,951
JBrowse link
G APOL4 apolipoprotein L4 increases expression ISO Chlormequat results in increased expression of APOL9A protein CTD PMID:34958886 NCBI chr22:36,189,128...36,204,833
Ensembl chr22:36,189,124...36,204,840
JBrowse link
G ARHGAP20 Rho GTPase activating protein 20 increases expression ISO Chlormequat results in increased expression of ARHGAP20 protein CTD PMID:34958886 NCBI chr11:110,577,043...110,713,189
Ensembl chr11:110,577,042...110,713,189
JBrowse link
G ATL1 atlastin GTPase 1 increases expression ISO Chlormequat results in increased expression of ATL1 protein CTD PMID:34958886 NCBI chr14:50,533,082...50,633,068
Ensembl chr14:50,532,509...50,634,017
JBrowse link
G ATP10B ATPase phospholipid transporting 10B (putative) increases expression ISO Chlormequat results in increased expression of ATP10B protein CTD PMID:34958886 NCBI chr 5:160,563,120...160,929,360
Ensembl chr 5:160,563,120...160,852,214
JBrowse link
G B9D2 B9 domain containing 2 increases expression ISO Chlormequat results in increased expression of B9D2 protein CTD PMID:34958886 NCBI chr19:41,354,417...41,364,149
Ensembl chr19:41,354,417...41,364,165
JBrowse link
G BET1L Bet1 golgi vesicular membrane trafficking protein like increases expression ISO Chlormequat results in increased expression of BET1L protein CTD PMID:34958886 NCBI chr11:202,924...207,399
Ensembl chr11:167,784...207,399
JBrowse link
G BGLAP bone gamma-carboxyglutamate protein decreases expression ISO Chlormequat results in decreased expression of BGLAP protein CTD PMID:28214531 NCBI chr 1:156,242,184...156,243,317
Ensembl chr 1:156,242,184...156,243,317
JBrowse link
G C1QC complement C1q C chain increases expression ISO Chlormequat results in increased expression of C1QC protein CTD PMID:34958886 NCBI chr 1:22,643,633...22,648,108
Ensembl chr 1:22,643,014...22,648,110
JBrowse link
G CAAP1 caspase activity and apoptosis inhibitor 1 decreases expression ISO Chlormequat results in decreased expression of CAAP1 protein CTD PMID:34958886 NCBI chr 9:26,840,685...26,892,802
Ensembl chr 9:26,840,685...26,892,803
JBrowse link
G CBX1 chromobox 1 increases expression ISO Chlormequat results in increased expression of CBX1 protein CTD PMID:34958886 NCBI chr17:48,070,059...48,101,478
Ensembl chr17:48,070,052...48,101,478
JBrowse link
G CCDC32 coiled-coil domain containing 32 increases expression ISO Chlormequat results in increased expression of CCDC32 protein CTD PMID:34958886 NCBI chr15:40,520,993...40,565,042
Ensembl chr15:40,528,683...40,565,054
JBrowse link
G CCNYL1 cyclin Y like 1 increases expression ISO Chlormequat results in increased expression of CCNYL1 protein CTD PMID:34958886 NCBI chr 2:207,711,640...207,756,174
Ensembl chr 2:207,711,540...207,761,839
JBrowse link
G CCS copper chaperone for superoxide dismutase increases expression ISO Chlormequat results in increased expression of CCS protein CTD PMID:34958886 NCBI chr11:66,593,185...66,606,019
Ensembl chr11:66,593,153...66,606,019
JBrowse link
G CD151 CD151 molecule (Raph blood group) decreases expression ISO Chlormequat results in decreased expression of CD151 protein CTD PMID:34958886 NCBI chr11:832,952...838,831
Ensembl chr11:832,887...839,831
JBrowse link
G CD55 CD55 molecule (Cromer blood group) increases expression ISO Chlormequat results in increased expression of CD55 protein CTD PMID:34958886 NCBI chr 1:207,321,678...207,360,966
Ensembl chr 1:207,321,519...207,386,804
JBrowse link
G CFAP298 cilia and flagella associated protein 298 increases expression ISO Chlormequat results in increased expression of CFAP298 protein CTD PMID:34958886 NCBI chr21:32,599,354...32,612,377
Ensembl chr21:32,592,079...32,612,603
JBrowse link
G CHMP7 charged multivesicular body protein 7 increases expression ISO Chlormequat results in increased expression of CHMP7 protein CTD PMID:34958886 NCBI chr 8:23,243,637...23,261,999
Ensembl chr 8:23,243,637...23,262,000
JBrowse link
G COPRS coordinator of PRMT5 and differentiation stimulator increases expression ISO Chlormequat results in increased expression of COPRS protein CTD PMID:34958886 NCBI chr17:31,851,871...31,859,244
Ensembl chr17:31,851,871...31,859,291
JBrowse link
G COQ4 coenzyme Q4 increases expression ISO Chlormequat results in increased expression of COQ4 protein CTD PMID:34958886 NCBI chr 9:128,322,839...128,334,072
Ensembl chr 9:128,322,544...128,334,072
JBrowse link
G CREB1 cAMP responsive element binding protein 1 increases phosphorylation ISO Chlormequat results in increased phosphorylation of CREB1 protein CTD PMID:38552810 NCBI chr 2:207,529,962...207,605,988
Ensembl chr 2:207,529,737...207,605,988
JBrowse link
G CSNK1A1 casein kinase 1 alpha 1 increases expression ISO Chlormequat results in increased expression of CSNK1A1 protein CTD PMID:34958886 NCBI chr 5:149,492,982...149,551,439
Ensembl chr 5:149,492,982...149,551,471
JBrowse link
G CTSS cathepsin S decreases expression ISO Chlormequat results in decreased expression of CTSS protein CTD PMID:34958886 NCBI chr 1:150,730,188...150,765,778
Ensembl chr 1:150,730,079...150,765,957
JBrowse link
G CYP11A1 cytochrome P450 family 11 subfamily A member 1 decreases expression ISO Chlormequat results in decreased expression of CYP11A1 protein CTD PMID:29447956 NCBI chr15:74,337,762...74,367,646
Ensembl chr15:74,337,759...74,367,646
JBrowse link
G CYP7A1 cytochrome P450 family 7 subfamily A member 1 increases expression EXP Chlormequat results in increased expression of CYP7A1 protein CTD PMID:32194361 NCBI chr 8:58,490,178...58,500,163
Ensembl chr 8:58,490,178...58,500,163
JBrowse link
G DAP death associated protein decreases expression ISO Chlormequat results in decreased expression of DAP protein CTD PMID:34958886 NCBI chr 5:10,679,230...10,761,234
Ensembl chr 5:10,679,230...10,761,234
JBrowse link
G DCAF13 DDB1 and CUL4 associated factor 13 increases expression ISO Chlormequat results in increased expression of DCAF13 protein CTD PMID:34958886 NCBI chr 8:103,415,386...103,443,453
Ensembl chr 8:103,414,714...103,443,453
JBrowse link
G DCTN6 dynactin subunit 6 increases expression ISO Chlormequat results in increased expression of DCTN6 protein CTD PMID:34958886 NCBI chr 8:30,156,369...30,183,639
Ensembl chr 8:30,156,319...30,183,639
JBrowse link
G DDIT3 DNA damage inducible transcript 3 multiple interactions
increases expression
ISO 4-phenylbutyric acid inhibits the reaction [Chlormequat results in increased expression of DDIT3 protein] CTD PMID:34958886 NCBI chr12:57,516,588...57,520,517
Ensembl chr12:57,516,588...57,521,737
JBrowse link
G DEGS1 delta 4-desaturase, sphingolipid 1 increases expression ISO Chlormequat results in increased expression of DEGS1 protein CTD PMID:34958886 NCBI chr 1:224,183,240...224,193,441
Ensembl chr 1:224,175,756...224,193,441
JBrowse link
G DNAJC14 DnaJ heat shock protein family (Hsp40) member C14 increases expression ISO Chlormequat results in increased expression of DNAJC14 protein CTD PMID:34958886 NCBI chr12:55,820,985...55,830,775
Ensembl chr12:55,820,960...55,830,824
JBrowse link
G DNMBP dynamin binding protein increases expression ISO Chlormequat results in increased expression of DNMBP protein CTD PMID:34958886 NCBI chr10:99,875,571...100,009,947
Ensembl chr10:99,875,577...100,009,947
JBrowse link
G DYNLT3 dynein light chain Tctex-type 3 increases expression ISO Chlormequat results in increased expression of DYNLT3 protein CTD PMID:34958886 NCBI chr  X:37,838,836...37,847,571
Ensembl chr  X:37,836,757...37,847,571
JBrowse link
G EARS2 glutamyl-tRNA synthetase 2, mitochondrial increases expression ISO Chlormequat results in increased expression of EARS2 protein CTD PMID:34958886 NCBI chr16:23,520,754...23,557,375
Ensembl chr16:23,520,754...23,557,731
JBrowse link
G EEF1A2 eukaryotic translation elongation factor 1 alpha 2 decreases expression ISO Chlormequat results in decreased expression of EEF1A2 protein CTD PMID:34958886 NCBI chr20:63,488,014...63,499,083
Ensembl chr20:63,488,013...63,499,239
JBrowse link
G ELOVL1 ELOVL fatty acid elongase 1 increases expression ISO Chlormequat results in increased expression of ELOVL1 protein CTD PMID:34958886 NCBI chr 1:43,363,401...43,368,011
Ensembl chr 1:43,363,398...43,368,074
JBrowse link
G ELOVL5 ELOVL fatty acid elongase 5 increases expression ISO Chlormequat results in increased expression of ELOVL5 protein CTD PMID:34958886 NCBI chr 6:53,267,404...53,348,950
Ensembl chr 6:53,267,398...53,349,179
JBrowse link
G ENO3 enolase 3 decreases expression ISO Chlormequat results in decreased expression of ENO3 protein CTD PMID:34958886 NCBI chr17:4,948,710...4,957,129
Ensembl chr17:4,948,092...4,957,131
JBrowse link
G EVC EvC ciliary complex subunit 1 increases expression ISO Chlormequat results in increased expression of EVC protein CTD PMID:34958886 NCBI chr 4:5,711,201...5,829,057
Ensembl chr 4:5,711,201...5,814,305
JBrowse link
G FABP4 fatty acid binding protein 4 decreases expression ISO Chlormequat results in decreased expression of FABP4 protein CTD PMID:34958886 NCBI chr 8:81,478,419...81,483,233
Ensembl chr 8:81,478,419...81,483,236
JBrowse link
G FANCD2 FA complementation group D2 decreases expression ISO Chlormequat results in decreased expression of FANCD2 protein CTD PMID:34958886 NCBI chr 3:10,026,437...10,101,932
Ensembl chr 3:10,026,370...10,101,932
JBrowse link
G FBLN1 fibulin 1 increases expression ISO Chlormequat results in increased expression of FBLN1 protein CTD PMID:34958886 NCBI chr22:45,502,883...45,601,135
Ensembl chr22:45,502,238...45,601,135
JBrowse link
G FOS Fos proto-oncogene, AP-1 transcription factor subunit decreases expression ISO Chlormequat results in decreased expression of FOS protein CTD PMID:34958886 NCBI chr14:75,278,828...75,282,230
Ensembl chr14:75,278,826...75,283,190
JBrowse link
G FOXK2 forkhead box K2 decreases expression ISO Chlormequat results in decreased expression of FOXK2 protein CTD PMID:34958886 NCBI chr17:82,519,732...82,604,602
Ensembl chr17:82,519,713...82,644,662
JBrowse link
G GABARAP GABA type A receptor-associated protein increases expression ISO Chlormequat results in increased expression of GABARAP protein CTD PMID:34958886 NCBI chr17:7,240,008...7,242,449
Ensembl chr17:7,240,008...7,242,449
JBrowse link
G GH1 growth hormone 1 increases expression ISO Chlormequat results in increased expression of GH1 protein CTD PMID:31704167 PMID:32622971 PMID:38552810 NCBI chr17:63,917,203...63,918,839
Ensembl chr17:63,917,200...63,918,839
JBrowse link
G GHR growth hormone receptor decreases expression ISO Chlormequat results in decreased expression of GHR mRNA CTD PMID:28214531 NCBI chr 5:42,423,439...42,721,878
Ensembl chr 5:42,423,439...42,721,878
JBrowse link
G GHRH growth hormone releasing hormone increases expression ISO Chlormequat results in increased expression of GHRH protein CTD PMID:32622971 PMID:38552810 NCBI chr20:37,251,086...37,261,814
Ensembl chr20:37,251,086...37,261,819
JBrowse link
G GNAI1 G protein subunit alpha i1 increases expression ISO Chlormequat results in increased expression of GNAI1 protein CTD PMID:34958886 NCBI chr 7:80,134,831...80,226,181
Ensembl chr 7:79,768,028...80,226,181
JBrowse link
G GNG5 G protein subunit gamma 5 decreases expression ISO Chlormequat results in decreased expression of GNG5 protein CTD PMID:34958886 NCBI chr 1:84,498,325...84,506,581
Ensembl chr 1:84,498,323...84,506,581
JBrowse link
G GNRH1 gonadotropin releasing hormone 1 increases expression ISO Chlormequat results in increased expression of GNRH1 protein CTD PMID:29447956 NCBI chr 8:25,419,258...25,425,040
Ensembl chr 8:25,419,258...25,424,654
JBrowse link
G GSTA2 glutathione S-transferase alpha 2 increases expression ISO Chlormequat results in increased expression of GSTA2 protein CTD PMID:34958886 NCBI chr 6:52,750,087...52,763,475
Ensembl chr 6:52,750,087...52,763,475
JBrowse link
G GTF2H5 general transcription factor IIH subunit 5 increases expression ISO Chlormequat results in increased expression of GTF2H5 protein CTD PMID:34958886 NCBI chr 6:158,168,350...158,199,344
Ensembl chr 6:158,168,350...158,199,344
JBrowse link
G H1-0 H1.0 linker histone increases expression ISO Chlormequat results in increased expression of H1-0 protein CTD PMID:34958886 NCBI chr22:37,805,229...37,807,432
Ensembl chr22:37,805,229...37,807,432
JBrowse link
G H1-5 H1.5 linker histone, cluster member increases expression ISO Chlormequat results in increased expression of H1-5 protein CTD PMID:34958886 NCBI chr 6:27,866,792...27,867,588
Ensembl chr 6:27,866,792...27,867,588
JBrowse link
G HEBP2 heme binding protein 2 increases expression ISO Chlormequat results in increased expression of HEBP2 protein CTD PMID:34958886 NCBI chr 6:138,403,531...138,422,197
Ensembl chr 6:138,403,531...138,422,197
JBrowse link
G HERPUD2 HERPUD family member 2 increases expression ISO Chlormequat results in increased expression of HERPUD2 protein CTD PMID:34958886 NCBI chr 7:35,632,659...35,695,135
Ensembl chr 7:35,632,659...35,697,459
JBrowse link
G HNRNPC heterogeneous nuclear ribonucleoprotein C increases expression ISO Chlormequat results in increased expression of HNRNPC protein CTD PMID:34958886 NCBI chr14:21,209,147...21,269,442
Ensembl chr14:21,209,136...21,269,494
JBrowse link
G HSD3B1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 decreases expression ISO Chlormequat results in decreased expression of HSD3B1 protein CTD PMID:29447956 NCBI chr 1:119,507,203...119,515,058
Ensembl chr 1:119,507,198...119,515,054
JBrowse link
G HSPA5 heat shock protein family A (Hsp70) member 5 multiple interactions
increases expression
ISO 4-phenylbutyric acid inhibits the reaction [Chlormequat results in increased expression of HSPA5 protein] CTD PMID:34958886 NCBI chr 9:125,234,853...125,241,343
Ensembl chr 9:125,234,853...125,241,382
JBrowse link
G IGF1 insulin like growth factor 1 affects expression
increases expression
ISO Chlormequat affects the expression of IGF1 protein
Chlormequat results in increased expression of IGF1 protein
CTD PMID:28214531 PMID:31704167 NCBI chr12:102,395,874...102,481,839
Ensembl chr12:102,395,874...102,481,744
JBrowse link
G INA internexin neuronal intermediate filament protein alpha decreases expression ISO Chlormequat results in decreased expression of INA protein CTD PMID:34958886 NCBI chr10:103,277,138...103,290,346
Ensembl chr10:103,277,138...103,290,346
JBrowse link
G ISOC2 isochorismatase domain containing 2 increases expression ISO Chlormequat results in increased expression of ISOC2 protein CTD PMID:34958886 NCBI chr19:55,452,985...55,461,642
Ensembl chr19:55,452,985...55,462,343
JBrowse link
G ITGB1BP1 integrin subunit beta 1 binding protein 1 increases expression ISO Chlormequat results in increased expression of ITGB1BP1 protein CTD PMID:34958886 NCBI chr 2:9,403,475...9,423,569
Ensembl chr 2:9,403,475...9,423,528
JBrowse link
G KAZN kazrin, periplakin interacting protein increases expression ISO Chlormequat results in increased expression of KAZN protein CTD PMID:34958886 NCBI chr 1:13,892,824...15,118,043
Ensembl chr 1:13,892,792...15,118,043
JBrowse link
G KLHL26 kelch like family member 26 decreases expression ISO Chlormequat results in decreased expression of KLHL26 protein CTD PMID:34958886 NCBI chr19:18,637,028...18,671,721
Ensembl chr19:18,637,025...18,671,721
JBrowse link
G KLHL7 kelch like family member 7 decreases expression ISO Chlormequat results in decreased expression of KLHL7 protein CTD PMID:34958886 NCBI chr 7:23,105,785...23,177,914
Ensembl chr 7:23,105,758...23,177,914
JBrowse link
G LDB1 LIM domain binding 1 increases expression ISO Chlormequat results in increased expression of LDB1 protein CTD PMID:34958886 NCBI chr10:102,102,088...102,121,442
Ensembl chr10:102,106,489...102,120,368
JBrowse link
G LHB luteinizing hormone subunit beta increases expression ISO Chlormequat results in increased expression of LHB protein CTD PMID:29447956 NCBI chr19:49,015,980...49,019,498
Ensembl chr19:49,015,980...49,017,091
JBrowse link
G LRRC7 leucine rich repeat containing 7 increases expression ISO Chlormequat results in increased expression of LRRC7 protein CTD PMID:34958886 NCBI chr 1:69,567,922...70,144,364
Ensembl chr 1:69,567,922...70,151,945
JBrowse link
G MACROH2A1 macroH2A.1 histone increases expression ISO Chlormequat results in increased expression of MACROH2A1 protein CTD PMID:34958886 NCBI chr 5:135,334,381...135,399,887
Ensembl chr 5:135,334,381...135,399,914
JBrowse link
G MACROH2A2 macroH2A.2 histone increases expression ISO Chlormequat results in increased expression of MACROH2A2 protein CTD PMID:34958886 NCBI chr10:70,052,846...70,112,282
Ensembl chr10:70,052,544...70,112,282
JBrowse link
G MAP4 microtubule associated protein 4 decreases expression ISO Chlormequat results in decreased expression of MAP4 protein CTD PMID:34958886 NCBI chr 3:47,850,695...48,088,848
Ensembl chr 3:47,850,690...48,089,272
JBrowse link
G MGAT4B alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B increases expression ISO Chlormequat results in increased expression of MGAT4B protein CTD PMID:34958886 NCBI chr 5:179,797,597...179,806,866
Ensembl chr 5:179,797,597...179,806,952
JBrowse link
G MOSPD3 motile sperm domain containing 3 decreases expression ISO Chlormequat results in decreased expression of MOSPD3 protein CTD PMID:34958886 NCBI chr 7:100,612,162...100,615,377
Ensembl chr 7:100,612,102...100,615,384
JBrowse link
G MOV10 Mov10 RNA helicase increases expression ISO Chlormequat results in increased expression of MOV10 protein CTD PMID:34958886 NCBI chr 1:112,674,439...112,700,739
Ensembl chr 1:112,673,141...112,700,756
JBrowse link
G MPP2 MAGUK p55 scaffold protein 2 decreases expression ISO Chlormequat results in decreased expression of MPP2 protein CTD PMID:34958886 NCBI chr17:43,875,360...43,909,711
Ensembl chr17:43,875,357...43,909,711
JBrowse link
G MPV17L2 MPV17 mitochondrial inner membrane protein like 2 increases expression ISO Chlormequat results in increased expression of MPV17L2 protein CTD PMID:34958886 NCBI chr19:18,193,218...18,196,948
Ensembl chr19:18,193,218...18,196,948
JBrowse link
G MRPL51 mitochondrial ribosomal protein L51 increases expression ISO Chlormequat results in increased expression of MRPL51 protein CTD PMID:34958886 NCBI chr12:6,491,886...6,493,262
Ensembl chr12:6,491,886...6,493,841
JBrowse link
G MRPL54 mitochondrial ribosomal protein L54 increases expression ISO Chlormequat results in increased expression of MRPL54 protein CTD PMID:34958886 NCBI chr19:3,762,682...3,767,565
Ensembl chr19:3,762,682...3,768,575
JBrowse link
G MRPS14 mitochondrial ribosomal protein S14 increases expression ISO Chlormequat results in increased expression of MRPS14 protein CTD PMID:34958886 NCBI chr 1:175,012,958...175,023,425
Ensembl chr 1:175,010,789...175,023,425
JBrowse link
G MTRFR mitochondrial translation release factor in rescue increases expression ISO Chlormequat results in increased expression of MTRFR protein CTD PMID:34958886 NCBI chr12:123,232,914...123,257,960
Ensembl chr12:123,233,385...123,258,079
JBrowse link
G NCL nucleolin increases expression ISO Chlormequat results in increased expression of NCL protein CTD PMID:34958886 NCBI chr 2:231,453,531...231,464,484
Ensembl chr 2:231,453,531...231,483,641
JBrowse link
G NHP2 NHP2 ribonucleoprotein increases expression ISO Chlormequat results in increased expression of NHP2 protein CTD PMID:34958886 NCBI chr 5:178,149,463...178,153,885
Ensembl chr 5:178,149,463...178,153,894
JBrowse link
G NIPA1 NIPA magnesium transporter 1 decreases expression ISO Chlormequat results in decreased expression of NIPA1 protein CTD PMID:34958886 NCBI chr15:22,786,225...22,829,789
Ensembl chr15:22,773,063...22,829,789
JBrowse link
G NPR3 natriuretic peptide receptor 3 decreases expression ISO Chlormequat results in decreased expression of NPR3 protein CTD PMID:34958886 NCBI chr 5:32,690,872...32,791,720
Ensembl chr 5:32,689,070...32,791,724
JBrowse link
G NR3C2 nuclear receptor subfamily 3 group C member 2 increases expression ISO Chlormequat results in increased expression of NR3C2 protein CTD PMID:34958886 NCBI chr 4:148,078,764...148,445,508
Ensembl chr 4:148,078,762...148,444,698
JBrowse link
G ORAI1 ORAI calcium release-activated calcium modulator 1 increases expression ISO Chlormequat results in increased expression of ORAI1 protein CTD PMID:34958886 NCBI chr12:121,626,530...121,643,109
Ensembl chr12:121,626,509...121,643,218
JBrowse link
G PABPC1 poly(A) binding protein cytoplasmic 1 increases expression ISO Chlormequat results in increased expression of PABPC1 protein CTD PMID:34958886 NCBI chr 8:100,702,916...100,722,088
Ensembl chr 8:100,685,816...100,722,809
JBrowse link
G PABPC4 poly(A) binding protein cytoplasmic 4 increases expression ISO Chlormequat results in increased expression of PABPC4 protein CTD PMID:34958886 NCBI chr 1:39,560,816...39,576,790
Ensembl chr 1:39,560,709...39,576,790
JBrowse link
G PCCB propionyl-CoA carboxylase subunit beta increases expression ISO Chlormequat results in increased expression of PCCB protein CTD PMID:34958886 NCBI chr 3:136,250,340...136,330,169
Ensembl chr 3:136,250,340...136,337,896
JBrowse link
G PEX26 peroxisomal biogenesis factor 26 increases expression ISO Chlormequat results in increased expression of PEX26 protein CTD PMID:34958886 NCBI chr22:18,077,990...18,105,396
Ensembl chr22:18,077,923...18,105,396
JBrowse link
G PGPEP1 pyroglutamyl-peptidase I increases expression ISO Chlormequat results in increased expression of PGPEP1 protein CTD PMID:34958886 NCBI chr19:18,340,598...18,369,950
Ensembl chr19:18,340,598...18,369,950
JBrowse link
G PHLDB1 pleckstrin homology like domain family B member 1 increases expression ISO Chlormequat results in increased expression of PHLDB1 protein CTD PMID:34958886 NCBI chr11:118,606,436...118,658,028
Ensembl chr11:118,606,440...118,658,031
JBrowse link
G PIAS3 protein inhibitor of activated STAT 3 decreases expression ISO Chlormequat results in decreased expression of PIAS3 protein CTD PMID:34958886 NCBI chr 1:145,848,522...145,859,081
Ensembl chr 1:145,848,522...145,859,836
JBrowse link
G PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta increases expression ISO Chlormequat results in increased expression of PIK3CD protein CTD PMID:34958886 NCBI chr 1:9,627,258...9,729,114
Ensembl chr 1:9,629,889...9,729,114
JBrowse link
G PITPNM2 phosphatidylinositol transfer protein membrane associated 2 increases expression ISO Chlormequat results in increased expression of PITPNM2 protein CTD PMID:34958886 NCBI chr12:122,983,480...123,151,848
Ensembl chr12:122,983,480...123,151,090
JBrowse link
G POLE4 DNA polymerase epsilon 4, accessory subunit increases expression ISO Chlormequat results in increased expression of POLE4 protein CTD PMID:34958886 NCBI chr 2:74,958,643...74,970,128
Ensembl chr 2:74,958,643...74,970,128
JBrowse link
G POU1F1 POU class 1 homeobox 1 increases expression ISO Chlormequat results in increased expression of POU1F1 protein CTD PMID:38552810 NCBI chr 3:87,259,404...87,276,584
Ensembl chr 3:87,259,404...87,276,584
JBrowse link
G PPHLN1 periphilin 1 increases expression ISO Chlormequat results in increased expression of PPHLN1 protein CTD PMID:34958886 NCBI chr12:42,326,167...42,448,621
Ensembl chr12:42,238,447...42,459,715
JBrowse link
G PRKACA protein kinase cAMP-activated catalytic subunit alpha affects expression ISO Chlormequat affects the expression of PRKACA protein CTD PMID:38552810 NCBI chr19:14,091,688...14,117,762
Ensembl chr19:14,091,688...14,118,084
JBrowse link
G PRKAR1B protein kinase cAMP-dependent type I regulatory subunit beta increases expression ISO Chlormequat results in increased expression of PRKAR1B protein CTD PMID:34958886 NCBI chr 7:549,197...728,934
Ensembl chr 7:549,197...727,650
JBrowse link
G PSMB7 proteasome 20S subunit beta 7 increases expression ISO Chlormequat results in increased expression of PSMB7 protein CTD PMID:34958886 NCBI chr 9:124,353,465...124,415,442
Ensembl chr 9:124,353,465...124,415,444
JBrowse link
G RAB6A RAB6A, member RAS oncogene family increases expression ISO Chlormequat results in increased expression of RAB6A protein CTD PMID:34958886 NCBI chr11:73,675,638...73,761,074
Ensembl chr11:73,675,638...73,761,137
JBrowse link
G RAD17 RAD17 checkpoint clamp loader component increases expression ISO Chlormequat results in increased expression of RAD17 protein CTD PMID:34958886 NCBI chr 5:69,369,293...69,414,801
Ensembl chr 5:69,369,293...69,414,801
JBrowse link
G RHOQ ras homolog family member Q increases expression ISO Chlormequat results in increased expression of RHOQ protein CTD PMID:34958886 NCBI chr 2:46,542,490...46,584,688
Ensembl chr 2:46,541,806...46,584,688
JBrowse link
G RNF113A ring finger protein 113A decreases expression ISO Chlormequat results in decreased expression of RNF113A1 protein CTD PMID:34958886 NCBI chr  X:119,870,475...119,871,733
Ensembl chr  X:119,870,475...119,871,733
JBrowse link
G RNF185 ring finger protein 185 increases expression
multiple interactions
ISO Chlormequat results in increased expression of RNF185 protein
4-phenylbutyric acid inhibits the reaction [Chlormequat results in increased expression of RNF185 protein]
CTD PMID:34958886 NCBI chr22:31,160,182...31,207,019
Ensembl chr22:31,160,182...31,207,019
JBrowse link
G RSPRY1 ring finger and SPRY domain containing 1 increases expression ISO Chlormequat results in increased expression of RSPRY1 protein CTD PMID:34958886 NCBI chr16:57,186,152...57,240,469
Ensembl chr16:57,186,137...57,240,469
JBrowse link
G RTN1 reticulon 1 decreases expression ISO Chlormequat results in decreased expression of RTN1 protein CTD PMID:34958886 NCBI chr14:59,595,976...59,870,776
Ensembl chr14:59,595,976...59,870,776
JBrowse link
G S100A1 S100 calcium binding protein A1 increases expression ISO Chlormequat results in increased expression of S100A1 protein CTD PMID:34958886 NCBI chr 1:153,628,434...153,632,039
Ensembl chr 1:153,627,926...153,632,039
JBrowse link
G SAMD8 sterile alpha motif domain containing 8 increases expression ISO Chlormequat results in increased expression of SAMD8 protein CTD PMID:34958886 NCBI chr10:75,099,593...75,182,123
Ensembl chr10:75,099,586...75,182,123
JBrowse link
G SAR1A secretion associated Ras related GTPase 1A increases expression ISO Chlormequat results in increased expression of SAR1A protein CTD PMID:34958886 NCBI chr10:70,147,289...70,170,514
Ensembl chr10:70,147,289...70,170,523
JBrowse link
G SHROOM1 shroom family member 1 decreases expression ISO Chlormequat results in decreased expression of SHROOM1 protein CTD PMID:34958886 NCBI chr 5:132,822,141...132,830,647
Ensembl chr 5:132,822,141...132,830,659
JBrowse link
G SKI SKI proto-oncogene increases expression ISO Chlormequat results in increased expression of SKI protein CTD PMID:34958886 NCBI chr 1:2,228,319...2,310,213
Ensembl chr 1:2,227,388...2,310,213
JBrowse link
G SLC48A1 solute carrier family 48 member 1 decreases expression ISO Chlormequat results in decreased expression of SLC48A1 protein CTD PMID:34958886 NCBI chr12:47,753,934...47,782,751
Ensembl chr12:47,753,916...47,782,751
JBrowse link
G SLIT3 slit guidance ligand 3 increases expression ISO Chlormequat results in increased expression of SLIT3 protein CTD PMID:34958886 NCBI chr 5:168,661,740...169,301,139
Ensembl chr 5:168,661,740...169,301,139
JBrowse link
G SLU7 SLU7 homolog, splicing factor increases expression ISO Chlormequat results in increased expression of SLU7 protein CTD PMID:34958886 NCBI chr 5:160,401,641...160,419,081
Ensembl chr 5:160,401,641...160,421,711
JBrowse link
G SMIM26 small integral membrane protein 26 decreases expression ISO Chlormequat results in decreased expression of SMIM26 protein CTD PMID:34958886 NCBI chr20:18,567,432...18,569,611
Ensembl chr20:18,567,347...18,569,563
JBrowse link
G SPNS1 SPNS lysolipid transporter 1, lysophospholipid increases expression ISO Chlormequat results in increased expression of SPNS1 protein CTD PMID:34958886 NCBI chr16:28,974,778...28,984,765
Ensembl chr16:28,974,221...28,984,548
JBrowse link
G SPPL2B signal peptide peptidase like 2B increases expression ISO Chlormequat results in increased expression of SPPL2B protein CTD PMID:34958886 NCBI chr19:2,328,684...2,355,095
Ensembl chr19:2,328,615...2,355,095
JBrowse link
G SST somatostatin affects expression ISO Chlormequat affects the expression of SST protein CTD PMID:38552810 NCBI chr 3:187,668,912...187,670,394
Ensembl chr 3:187,668,912...187,670,394
JBrowse link
G ST3GAL1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 increases expression ISO Chlormequat results in increased expression of ST3GAL1 protein CTD PMID:34958886 NCBI chr 8:133,454,848...133,571,887
Ensembl chr 8:133,454,848...133,571,926
JBrowse link
G ST7L suppression of tumorigenicity 7 like decreases expression ISO Chlormequat results in decreased expression of ST7L protein CTD PMID:34958886 NCBI chr 1:112,517,803...112,619,684
Ensembl chr 1:112,523,514...112,620,825
JBrowse link
G STAR steroidogenic acute regulatory protein decreases expression ISO Chlormequat results in decreased expression of STAR protein CTD PMID:29447956 NCBI chr 8:38,142,700...38,150,952
Ensembl chr 8:38,142,700...38,150,992
JBrowse link
G STK26 serine/threonine kinase 26 increases expression ISO Chlormequat results in increased expression of STK26 protein CTD PMID:34958886 NCBI chr  X:132,023,302...132,075,943
Ensembl chr  X:132,023,302...132,075,943
JBrowse link
G SUSD2 sushi domain containing 2 increases expression ISO Chlormequat results in increased expression of SUSD2 protein CTD PMID:34958886 NCBI chr22:24,181,487...24,189,106
Ensembl chr22:24,181,487...24,189,106
JBrowse link
G TAF7 TATA-box binding protein associated factor 7 increases expression ISO Chlormequat results in increased expression of TAF7 protein CTD PMID:34958886 NCBI chr 5:141,318,490...141,320,784
Ensembl chr 5:141,259,884...141,320,784
JBrowse link
G TCAF1 TRPM8 channel associated factor 1 increases expression ISO Chlormequat results in increased expression of TCAF1 protein CTD PMID:34958886 NCBI chr 7:143,851,375...143,902,176
Ensembl chr 7:143,851,375...143,902,198
JBrowse link
G TCEANC transcription elongation factor A N-terminal and central domain containing decreases expression ISO Chlormequat results in decreased expression of TCEANC protein CTD PMID:34958886 NCBI chr  X:13,653,141...13,665,409
Ensembl chr  X:13,653,112...13,681,964
JBrowse link
G TENT2 terminal nucleotidyltransferase 2 increases expression ISO Chlormequat results in increased expression of TENT2 protein CTD PMID:34958886 NCBI chr 5:79,612,441...79,688,246
Ensembl chr 5:79,612,120...79,688,246
JBrowse link
G THEM4 thioesterase superfamily member 4 decreases expression ISO Chlormequat results in decreased expression of THEM4 protein CTD PMID:34958886 NCBI chr 1:151,870,866...151,909,511
Ensembl chr 1:151,870,866...151,909,637
JBrowse link
G THOC6 THO complex subunit 6 increases expression ISO Chlormequat results in increased expression of THOC6 protein CTD PMID:34958886 NCBI chr16:3,024,035...3,027,750
Ensembl chr16:3,024,027...3,027,755
JBrowse link
G TIRAP TIR domain containing adaptor protein increases expression ISO Chlormequat results in increased expression of TIRAP protein CTD PMID:34958886 NCBI chr11:126,283,093...126,294,933
Ensembl chr11:126,282,497...126,298,845
JBrowse link
G TKT transketolase increases expression ISO Chlormequat results in increased expression of TKT protein CTD PMID:34958886 NCBI chr 3:53,224,712...53,256,022
Ensembl chr 3:53,224,712...53,256,052
JBrowse link
G TMEM106C transmembrane protein 106C increases expression ISO Chlormequat results in increased expression of TMEM106C protein CTD PMID:34958886 NCBI chr12:47,963,596...47,968,878
Ensembl chr12:47,963,569...47,968,878
JBrowse link
G TMEM184C transmembrane protein 184C decreases expression ISO Chlormequat results in decreased expression of TMEM184C protein CTD PMID:34958886 NCBI chr 4:147,617,397...147,636,721
Ensembl chr 4:147,617,386...147,672,044
JBrowse link
G TMEM208 transmembrane protein 208 increases expression ISO Chlormequat results in increased expression of TMEM208 protein CTD PMID:34958886 NCBI chr16:67,227,130...67,229,278
Ensembl chr16:67,227,103...67,229,278
JBrowse link
G TMEM222 transmembrane protein 222 increases expression ISO Chlormequat results in increased expression of TMEM222 protein CTD PMID:34958886 NCBI chr 1:27,322,163...27,336,400
Ensembl chr 1:27,322,145...27,336,400
JBrowse link
G TNFSF11 TNF superfamily member 11 affects expression ISO Chlormequat affects the expression of TNFSF11 mRNA CTD PMID:28214531 NCBI chr13:42,562,736...42,608,013
Ensembl chr13:42,562,736...42,608,013
JBrowse link
G TP53I11 tumor protein p53 inducible protein 11 increases expression ISO Chlormequat results in increased expression of TP53I11 protein CTD PMID:34958886 NCBI chr11:44,932,348...44,951,306
Ensembl chr11:44,885,903...44,951,306
JBrowse link
G TRA2A transformer 2 alpha homolog increases expression ISO Chlormequat results in increased expression of TRA2A protein CTD PMID:34958886 NCBI chr 7:23,504,780...23,531,981
Ensembl chr 7:23,504,780...23,532,041
JBrowse link
G TRAM2 translocation associated membrane protein 2 decreases expression ISO Chlormequat results in decreased expression of TRAM2 protein CTD PMID:34958886 NCBI chr 6:52,497,408...52,577,060
Ensembl chr 6:52,497,408...52,577,060
JBrowse link
G TTC12 tetratricopeptide repeat domain 12 increases expression ISO Chlormequat results in increased expression of TTC12 protein CTD PMID:34958886 NCBI chr11:113,314,583...113,373,297
Ensembl chr11:113,314,579...113,383,544
JBrowse link
G UBE2D1 ubiquitin conjugating enzyme E2 D1 multiple interactions
increases expression
ISO 4-phenylbutyric acid inhibits the reaction [Chlormequat results in increased expression of UBE2D1 protein] CTD PMID:34958886 NCBI chr10:58,335,006...58,370,748
Ensembl chr10:58,334,979...58,370,751
JBrowse link
G UCP2 uncoupling protein 2 decreases expression ISO Chlormequat results in decreased expression of UCP2 protein CTD PMID:34958886 NCBI chr11:73,974,672...73,983,202
Ensembl chr11:73,974,061...73,982,843
JBrowse link
G WDR74 WD repeat domain 74 increases expression ISO Chlormequat results in increased expression of WDR74 protein CTD PMID:34958886 NCBI chr11:62,832,905...62,841,809
Ensembl chr11:62,832,342...62,841,809
JBrowse link
G WSB2 WD repeat and SOCS box containing 2 decreases expression ISO Chlormequat results in decreased expression of WSB2 protein CTD PMID:34958886 NCBI chr12:118,032,687...118,062,174
Ensembl chr12:118,032,687...118,062,430
JBrowse link
G ZEB1 zinc finger E-box binding homeobox 1 increases expression ISO Chlormequat results in increased expression of ZEB1 protein CTD PMID:34958886 NCBI chr10:31,318,417...31,529,804
Ensembl chr10:31,318,495...31,529,814
JBrowse link
cocaine hydrochloride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BMAL1 basic helix-loop-helix ARNT like 1 decreases expression ISO cocaine hydrochloride decreases expression of Bmal1 mRNA in caudate-putamen RGD PMID:15994025 RGD:405866348 NCBI chr11:13,276,652...13,387,266
Ensembl chr11:13,276,652...13,387,266
JBrowse link
G CLOCK clock circadian regulator increases expression ISO cocaine hydrochloride increases expression of Clock mRNA in caudate-putamen RGD PMID:15994025 RGD:405866348 NCBI chr 4:55,427,903...55,546,909
Ensembl chr 4:55,427,903...55,546,909
JBrowse link
G CRY1 cryptochrome circadian regulator 1 decreases expression
increases expression
ISO cocaine hydrochloride decreases expression of Cry1 mRNA in caudate-putamen
cocaine hydrochloride increases expression of Cry1 mRNA in hippocampal formation
RGD PMID:15994025 PMID:15994025 RGD:405866347, RGD:405866347 NCBI chr12:106,991,364...107,093,549
Ensembl chr12:106,991,364...107,093,549
JBrowse link
G CRY2 cryptochrome circadian regulator 2 decreases expression ISO cocaine hydrochloride decreases expression of Cry2 mRNA in caudate-putamen RGD PMID:15994025 RGD:405866347 NCBI chr11:45,847,118...45,883,244
Ensembl chr11:45,847,118...45,883,248
JBrowse link
G NPAS2 neuronal PAS domain protein 2 decreases expression ISO cocaine hydrochloride decreases expression of hippocampal formation and caudate-putamen RGD PMID:15994025 RGD:405866347 NCBI chr 2:100,818,723...100,996,829
Ensembl chr 2:100,820,139...100,996,829
JBrowse link
G PER1 period circadian regulator 1 increases expression ISO cocaine hydrochloride increases expression of Per1 mRNA in hippocampal formation and caudate-putamen RGD PMID:15994025 RGD:405866348 NCBI chr17:8,140,472...8,152,404
Ensembl chr17:8,140,467...8,156,506
JBrowse link
G PER2 period circadian regulator 2 increases expression
decreases expression
ISO ocaine hydrochloride increases expression of Per2 mRNA in hippocampal formation
cocaine hydrochloride decreases expression of Per2 mRNA in caudate-putamen
RGD PMID:15994025 PMID:15994025 RGD:405866348, RGD:405866348 NCBI chr 2:238,244,044...238,300,065
Ensembl chr 2:238,244,044...238,290,102
JBrowse link
G PER3 period circadian regulator 3 increases expression ISO cocaine hydrochloride increases expression of Per3 mRNA in hippocampal formation and caudate-putamen RGD PMID:15994025 RGD:405866348 NCBI chr 1:7,784,291...7,845,177
Ensembl chr 1:7,784,291...7,845,177
JBrowse link
colesevelam hydrochloride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CRP C-reactive protein decreases expression EXP Colesevelam Hydrochloride results in decreased expression of CRP protein CTD PMID:16616026 NCBI chr 1:159,712,289...159,714,589
Ensembl chr 1:159,712,289...159,714,589
JBrowse link
G HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase multiple interactions
increases expression
ISO Colesevelam Hydrochloride promotes the reaction [Simvastatin results in increased expression of HMGCR mRNA]
Colesevelam Hydrochloride results in increased expression of HMGCR mRNA
CTD PMID:22120639 NCBI chr 5:75,336,529...75,362,116
Ensembl chr 5:75,336,329...75,364,001
JBrowse link
G LDLR low density lipoprotein receptor increases expression ISO Colesevelam Hydrochloride results in increased expression of LDLR mRNA CTD PMID:22120639 NCBI chr19:11,089,463...11,133,820
Ensembl chr19:11,089,418...11,133,820
JBrowse link
colforsin daropate hydrochloride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA1 ATP binding cassette subfamily A member 1 multiple interactions EXP Colforsin promotes the reaction [Diethylhexyl Phthalate results in decreased expression of ABCA1 mRNA] CTD PMID:37536456 NCBI chr 9:104,781,006...104,928,155
Ensembl chr 9:104,781,006...104,928,155
JBrowse link
G ABCB1 ATP binding cassette subfamily B member 1 increases expression
multiple interactions
EXP Colforsin results in increased expression of ABCB1 mRNA
N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Colforsin results in increased expression of ABCB1 mRNA]
CTD PMID:12926078 NCBI chr 7:87,503,017...87,713,295
Ensembl chr 7:87,503,017...87,713,323
JBrowse link
G ABCB4 ATP binding cassette subfamily B member 4 multiple interactions
decreases expression
EXP Colforsin inhibits the reaction [Doxorubicin results in increased expression of ABCB4 mRNA]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Colforsin results in decreased expression of ABCB4 mRNA] CTD PMID:12926078 NCBI chr 7:87,365,896...87,476,027
Ensembl chr 7:87,401,696...87,480,435
JBrowse link
G ABCC2 ATP binding cassette subfamily C member 2 increases expression EXP Colforsin results in increased expression of ABCC2 mRNA; Colforsin results in increased expression of ABCC2 protein CTD PMID:19580841 PMID:26049102 NCBI chr10:99,782,640...99,852,594
Ensembl chr10:99,782,640...99,852,594
JBrowse link
G ABCC4 ATP binding cassette subfamily C member 4 (PEL blood group) decreases expression
multiple interactions
EXP Colforsin results in decreased expression of ABCC4 mRNA
Valproic Acid inhibits the reaction [Colforsin results in decreased expression of ABCC4 mRNA]
CTD PMID:37385477 NCBI chr13:95,019,835...95,301,451
Ensembl chr13:95,019,835...95,301,475
JBrowse link
G ABCG2 ATP binding cassette subfamily G member 2 (JR blood group) increases expression
multiple interactions
EXP Colforsin results in increased expression of ABCG2 mRNA
Colforsin inhibits the reaction [anandamide inhibits the reaction [CREB1 protein modified form binds to ABCG2 promoter]]
CTD PMID:19580841 PMID:30610963 NCBI chr 4:88,090,264...88,231,626
Ensembl chr 4:88,090,150...88,231,628
JBrowse link
G ACACA acetyl-CoA carboxylase alpha increases phosphorylation ISO Colforsin results in increased phosphorylation of ACACA protein CTD PMID:18390901 NCBI chr17:37,084,992...37,406,836
Ensembl chr17:37,084,992...37,406,836
JBrowse link
G ACHE acetylcholinesterase (Yt blood group) increases activity
increases expression
ISO Colforsin results in increased activity of ACHE protein; Colforsin results in increased activity of ACHE protein alternative form
Colforsin results in increased expression of ACHE mRNA
CTD PMID:18514641 NCBI chr 7:100,889,994...100,896,994
Ensembl chr 7:100,889,994...100,896,974
JBrowse link
G ACSL3 acyl-CoA synthetase long chain family member 3 increases expression EXP Colforsin results in increased expression of ACSL3 mRNA CTD PMID:16751804 NCBI chr 2:222,861,036...222,944,639
Ensembl chr 2:222,860,942...222,944,639
JBrowse link
G ACTA2 actin alpha 2, smooth muscle decreases expression
multiple interactions
EXP
ISO
Colforsin results in decreased expression of ACTA2 protein
Colforsin inhibits the reaction [Carbon Tetrachloride results in increased expression of ACTA2 protein]
CTD PMID:21603974 PMID:27590029 NCBI chr10:88,935,074...88,991,337
Ensembl chr10:88,934,822...88,991,339
JBrowse link
G ADAM12 ADAM metallopeptidase domain 12 decreases expression EXP Colforsin results in decreased expression of ADAM12 mRNA CTD PMID:15313392 PMID:15967414 NCBI chr10:126,012,391...126,388,477
Ensembl chr10:126,012,381...126,388,477
JBrowse link
G ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif 1 decreases expression EXP Colforsin results in decreased expression of ADAMTS1 mRNA CTD PMID:15313392 PMID:15967414 NCBI chr21:26,835,755...26,845,409
Ensembl chr21:26,835,755...26,845,409
JBrowse link
G ADCY5 adenylate cyclase 5 multiple interactions ISO ADCY5 protein results in increased susceptibility to [Colforsin co-treated with Quinpirole] CTD PMID:12223546 NCBI chr 3:123,282,296...123,449,090
Ensembl chr 3:123,282,296...123,449,090
JBrowse link
G ADCY6 adenylate cyclase 6 affects response to substance ISO ADCY6 protein affects the susceptibility to Colforsin CTD PMID:12393090 NCBI chr12:48,766,194...48,789,974
Ensembl chr12:48,766,194...48,789,089
JBrowse link
G ADCY9 adenylate cyclase 9 multiple interactions
increases activity
ISO [Colforsin co-treated with Miconazole] results in increased activity of ADCY9 protein
Colforsin results in increased activity of ADCY9 protein
CTD PMID:30607468 NCBI chr16:3,953,387...4,116,442
Ensembl chr16:3,953,387...4,116,442
JBrowse link
G ADM adrenomedullin multiple interactions
increases expression
EXP cobaltous chloride inhibits the reaction [Valproic Acid inhibits the reaction [Colforsin results in increased expression of ADM mRNA]]; Valproic Acid inhibits the reaction [Colforsin results in increased expression of ADM mRNA] CTD PMID:38296531 NCBI chr11:10,305,073...10,307,397
Ensembl chr11:10,305,073...10,307,397
JBrowse link
G ADRA1A adrenoceptor alpha 1A multiple interactions EXP [Colforsin co-treated with 1-Methyl-3-isobutylxanthine] affects the reaction [[Phenylephrine binds to and results in increased activity of ADRA1A protein] which affects the transport of Potassium] CTD PMID:19419905 NCBI chr 8:26,748,150...26,867,379
Ensembl chr 8:26,748,150...26,867,278
JBrowse link
G ADRA2C adrenoceptor alpha 2C multiple interactions
affects localization
increases expression
EXP AKAP13 protein modified form affects the reaction [Colforsin affects the localization of ADRA2C protein]; AKAP13 protein modified form affects the reaction [Colforsin results in increased expression of ADRA2C mRNA] CTD PMID:24701590 NCBI chr 4:3,766,385...3,768,526
Ensembl chr 4:3,766,348...3,768,526
JBrowse link
G ADRB1 adrenoceptor beta 1 affects response to substance
multiple interactions
EXP ADRB1 protein polymorphism affects the susceptibility to Colforsin
[[Colforsin co-treated with 1-Methyl-3-isobutylxanthine] results in increased activity of [ADRB1 protein binds to ADRB2 protein]] affects the reaction [KCNH2 protein results in increased transport of Potassium]; [Colforsin co-treated with 1-Methyl-3-isobutylxanthine] promotes the reaction [[ADRB1 protein binds to ADRB2 protein] which results in increased abundance of Cyclic AMP]; [Colforsin co-treated with 1-Methyl-3-isobutylxanthine] results in increased activity of [ADRB1 protein binds to ADRB2 protein]
CTD PMID:14502278 PMID:19419905 NCBI chr10:114,043,866...114,046,904
Ensembl chr10:114,043,866...114,046,904
JBrowse link
G ADRB2 adrenoceptor beta 2 multiple interactions
increases expression
increases phosphorylation
EXP [[Colforsin co-treated with 1-Methyl-3-isobutylxanthine] results in increased activity of [ADRB1 protein binds to ADRB2 protein]] affects the reaction [KCNH2 protein results in increased transport of Potassium]; [Colforsin co-treated with 1-Methyl-3-isobutylxanthine] promotes the reaction [[ADRB1 protein binds to ADRB2 protein] which results in increased abundance of Cyclic AMP]; [Colforsin co-treated with 1-Methyl-3-isobutylxanthine] results in increased activity of [ADRB1 protein binds to ADRB2 protein]
Colforsin results in increased expression of ADRB2 mRNA
Colforsin results in increased phosphorylation of ADRB2 protein
CTD PMID:14722251 PMID:19419905 PMID:24705868 NCBI chr 5:148,826,611...148,828,623
Ensembl chr 5:148,826,611...148,828,623
JBrowse link
G ADRB3 adrenoceptor beta 3 decreases expression ISO Colforsin results in decreased expression of ADRB3 mRNA CTD PMID:10725275 NCBI chr 8:37,962,990...37,966,599
Ensembl chr 8:37,962,990...37,966,599
JBrowse link
G AHR aryl hydrocarbon receptor multiple interactions
affects localization
EXP
ISO
[Colforsin results in increased activity of AHR protein] which results in increased expression of CXCL8 mRNA; [Colforsin results in increased activity of AHR protein] which results in increased expression of CXCL8 protein; [Colforsin results in increased activity of AHR protein] which results in increased secretion of CXCL8 protein; Colforsin promotes the reaction [[AHR protein binds to RELB protein] which binds to CXCL8 promoter]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Colforsin promotes the reaction [[AHR protein binds to RELB protein] which binds to CXCL8 promoter]]; PDE2A protein inhibits the reaction [Colforsin affects the localization of AHR protein]
AHR protein inhibits the reaction [[Colforsin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of PER1 mRNA]
CTD PMID:15972329 PMID:17329248 PMID:17823304 PMID:23291558 NCBI chr 7:17,298,652...17,346,147
Ensembl chr 7:16,916,359...17,346,152
JBrowse link
G AKAP13 A-kinase anchoring protein 13 multiple interactions EXP AKAP13 protein modified form affects the reaction [Colforsin affects the localization of ADRA2C protein]; AKAP13 protein modified form affects the reaction [Colforsin results in increased expression of ADRA2C mRNA]; AKAP13 protein modified form inhibits the reaction [Colforsin results in increased phosphorylation of CREB1 protein] CTD PMID:24701590 NCBI chr15:85,380,603...85,749,358
Ensembl chr15:85,380,571...85,749,358
JBrowse link
G AKR1C3 aldo-keto reductase family 1 member C3 decreases expression EXP Colforsin results in decreased expression of AKR1C3 mRNA CTD PMID:28235592 NCBI chr10:5,048,781...5,107,686
Ensembl chr10:5,035,354...5,107,686
JBrowse link
G AKT1 AKT serine/threonine kinase 1 multiple interactions ISO Colforsin inhibits the reaction [Oxidopamine results in decreased phosphorylation of AKT1 protein] CTD PMID:16339297 NCBI chr14:104,769,349...104,795,748
Ensembl chr14:104,769,349...104,795,759
JBrowse link
G AKT2 AKT serine/threonine kinase 2 multiple interactions ISO Colforsin inhibits the reaction [Oxidopamine results in decreased phosphorylation of AKT2 protein] CTD PMID:16339297 NCBI chr19:40,230,317...40,285,345
Ensembl chr19:40,230,317...40,285,536
JBrowse link
G AKT3 AKT serine/threonine kinase 3 multiple interactions ISO Colforsin inhibits the reaction [Oxidopamine results in decreased phosphorylation of AKT3 protein] CTD PMID:16339297 NCBI chr 1:243,488,233...243,851,079
Ensembl chr 1:243,488,233...243,851,079
JBrowse link
G ALB albumin multiple interactions ISO Colforsin inhibits the reaction [Carbon Tetrachloride results in decreased expression of ALB protein] CTD PMID:27590029 NCBI chr 4:73,404,287...73,421,482
Ensembl chr 4:73,397,114...73,421,482
JBrowse link
G ALPI alkaline phosphatase, intestinal multiple interactions EXP Colforsin inhibits the reaction [Methotrexate results in increased activity of ALPI protein] CTD PMID:16598758 NCBI chr 2:232,456,153...232,460,753
Ensembl chr 2:232,456,125...232,460,753
JBrowse link
G ALPP alkaline phosphatase, placental multiple interactions
increases expression
EXP [Colforsin results in increased abundance of Cyclic AMP] which results in increased expression of ALPP mRNA; Chlorpromazine inhibits the reaction [Colforsin results in increased expression of ALPP mRNA]; Clozapine inhibits the reaction [Colforsin results in increased expression of ALPP mRNA]; Desipramine inhibits the reaction [Colforsin results in increased expression of ALPP mRNA] CTD PMID:16036225 NCBI chr 2:232,378,751...232,382,889
Ensembl chr 2:232,378,724...232,382,889
JBrowse link
G AOC1 amine oxidase copper containing 1 increases activity ISO Colforsin results in increased activity of AOC1 protein CTD PMID:2860926 NCBI chr 7:150,852,120...150,861,504
Ensembl chr 7:150,824,627...150,861,504
JBrowse link
G APPBP2 amyloid beta precursor protein binding protein 2 decreases expression EXP Colforsin results in decreased expression of APPBP2 mRNA CTD PMID:16751804 NCBI chr17:60,443,158...60,526,242
Ensembl chr17:60,443,158...60,526,242
JBrowse link
G AR androgen receptor multiple interactions
increases expression
EXP AR protein affects the reaction [Colforsin results in decreased expression of SESN1 protein]; AR protein promotes the reaction [Colforsin results in increased expression of HMGCR protein]; AR protein promotes the reaction [Colforsin results in increased expression of INSIG1 protein]; AR protein promotes the reaction [Colforsin results in increased expression of KLK2 protein]; AR protein promotes the reaction [Colforsin results in increased expression of KLK3 protein]; Colforsin promotes the reaction [Metribolone results in increased activity of AR protein]
Colforsin results in increased expression of AR protein
CTD PMID:16751804 PMID:17219378 NCBI chr  X:67,544,021...67,730,619
Ensembl chr  X:67,544,021...67,730,619
JBrowse link
G AREG amphiregulin increases expression
multiple interactions
EXP
ISO
Colforsin results in increased expression of AREG mRNA
N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Colforsin results in increased expression of AREG mRNA]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Colforsin results in increased expression of AREG protein]
CTD PMID:15284208 PMID:15313392 PMID:15474502 PMID:15967414 PMID:20378682 NCBI chr 4:74,445,136...74,455,005
Ensembl chr 4:74,445,136...74,455,005
JBrowse link
G ARRB1 arrestin beta 1 multiple interactions EXP Colforsin inhibits the reaction [[carvedilol co-treated with ARRB1 protein] results in increased expression of MIR190A mRNA] CTD PMID:24334028 NCBI chr11:75,260,122...75,351,661
Ensembl chr11:75,260,122...75,351,705
JBrowse link
G ATP5MF-PTCD1 ATP5MF-PTCD1 readthrough multiple interactions EXP [Colforsin co-treated with Diethylhexyl Phthalate] affects the expression of ATP5MF-PTCD1 mRNA CTD PMID:35892601 NCBI chr 7:99,416,739...99,466,167
Ensembl chr 7:99,419,749...99,466,197
JBrowse link
G ATXN3 ataxin 3 decreases expression EXP Colforsin results in decreased expression of ATXN3 mRNA CTD PMID:16751804 NCBI chr14:92,044,775...92,106,582
Ensembl chr14:92,044,496...92,106,621
JBrowse link
G BCL2 BCL2 apoptosis regulator multiple interactions EXP [S-(1,2-dichlorovinyl)cysteine co-treated with Colforsin] results in decreased expression of BCL2 mRNA; S-(1,2-dichlorovinyl)cysteine inhibits the reaction [Colforsin results in increased expression of BCL2 mRNA] CTD PMID:36336211 PMID:37544576 NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128
JBrowse link
G BDNF brain derived neurotrophic factor multiple interactions
increases expression
EXP
ISO
1-bromopropane inhibits the reaction [Colforsin results in increased expression of BDNF mRNA]; 1-bromopropane inhibits the reaction [Colforsin results in increased expression of BDNF protein]
Colforsin inhibits the reaction [Caffeine results in decreased expression of BDNF mRNA]; Colforsin inhibits the reaction [Caffeine results in decreased expression of BDNF protein]
Colforsin results in increased expression of BDNF mRNA; Colforsin results in increased expression of BDNF protein
CTD PMID:19189864 PMID:35917217 NCBI chr11:27,654,893...27,722,030
Ensembl chr11:27,654,893...27,722,058
JBrowse link
G BMAL1 basic helix-loop-helix ARNT like 1 increases expression ISO Colforsin results in increased expression of BMAL1 mRNA CTD PMID:30524225 NCBI chr11:13,276,652...13,387,266
Ensembl chr11:13,276,652...13,387,266
JBrowse link
G BMP6 bone morphogenetic protein 6 multiple interactions EXP BMP6 protein inhibits the reaction [Colforsin results in increased expression of CYP11A1 mRNA]; BMP6 protein inhibits the reaction [Colforsin results in increased expression of CYP19A1 mRNA]; BMP6 protein inhibits the reaction [Colforsin results in increased expression of HSD3B1 mRNA]; BMP6 protein inhibits the reaction [Colforsin results in increased expression of OXT mRNA]; BMP6 protein inhibits the reaction [Colforsin results in increased expression of STAR mRNA]; BMP6 protein inhibits the reaction [Colforsin results in increased secretion of Progesterone]; FST protein inhibits the reaction [BMP6 protein inhibits the reaction [Colforsin results in increased secretion of Progesterone]] CTD PMID:18936084 NCBI chr 6:7,726,099...7,881,728
Ensembl chr 6:7,726,099...7,881,728
JBrowse link
G C4A complement C4A (Chido/Rodgers blood group) multiple interactions EXP [Colforsin co-treated with Diethylhexyl Phthalate] affects the expression of C4A mRNA CTD PMID:35892601 NCBI chr 6:31,982,057...32,002,681
Ensembl chr 6:31,982,057...32,002,681
JBrowse link
G C4B_2 complement component 4B (Chido/Rodgers blood group), copy 2 multiple interactions EXP [Colforsin co-treated with Diethylhexyl Phthalate] affects the expression of C4B_2 mRNA CTD PMID:35892601
G CACNA1G calcium voltage-gated channel subunit alpha1 G multiple interactions ISO Mibefradil inhibits the reaction [[Colforsin co-treated with 1-Methyl-3-isobutylxanthine] results in increased activity of CACNA1G protein]; Nickel inhibits the reaction [[Colforsin co-treated with 1-Methyl-3-isobutylxanthine] results in increased activity of CACNA1G protein] CTD PMID:17110049 NCBI chr17:50,560,715...50,627,474
Ensembl chr17:50,560,715...50,627,474
JBrowse link
G CACNA1H calcium voltage-gated channel subunit alpha1 H multiple interactions ISO Mibefradil inhibits the reaction [[Colforsin co-treated with 1-Methyl-3-isobutylxanthine] results in increased activity of CACNA1H protein]; Nickel inhibits the reaction [[Colforsin co-treated with 1-Methyl-3-isobutylxanthine] results in increased activity of CACNA1H protein] CTD PMID:17110049 NCBI chr16:1,153,106...1,221,768
Ensembl chr16:1,153,103...1,224,169
JBrowse link
G CACNA1I calcium voltage-gated channel subunit alpha1 I multiple interactions ISO Mibefradil inhibits the reaction [[Colforsin co-treated with 1-Methyl-3-isobutylxanthine] results in increased activity of CACNA1I protein]; Nickel inhibits the reaction [[Colforsin co-treated with 1-Methyl-3-isobutylxanthine] results in increased activity of CACNA1I protein] CTD PMID:17110049 NCBI chr22:39,570,753...39,689,735
Ensembl chr22:39,570,753...39,689,735
JBrowse link
G CALCRL calcitonin receptor like receptor multiple interactions EXP Colforsin inhibits the reaction [EDN1 protein results in increased expression of CALCRL mRNA] CTD PMID:25194819 NCBI chr 2:187,341,964...187,448,252
Ensembl chr 2:187,341,964...187,448,460
JBrowse link
G CAMKK2 calcium/calmodulin dependent protein kinase kinase 2 increases expression EXP Colforsin results in increased expression of CAMKK2 mRNA CTD PMID:16751804 NCBI chr12:121,237,692...121,297,819
Ensembl chr12:121,237,675...121,298,308
JBrowse link
G CASK calcium/calmodulin dependent serine protein kinase increases phosphorylation
multiple interactions
ISO Colforsin results in increased phosphorylation of CASK protein
Colforsin promotes the reaction [CASK protein modified form binds to TBR1 protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Colforsin results in increased phosphorylation of CASK protein]
CTD PMID:20067577 NCBI chr  X:41,514,934...41,923,554
Ensembl chr  X:41,514,934...41,923,554
JBrowse link
G CASP1 caspase 1 increases activity ISO Colforsin results in increased activity of CASP1 mRNA; Colforsin results in increased activity of CASP1 protein CTD PMID:21832250 NCBI chr11:105,025,443...105,036,686
Ensembl chr11:105,025,397...105,035,250
JBrowse link
G CASP3 caspase 3 increases activity
multiple interactions
EXP
ISO
Colforsin results in increased activity of CASP3 protein
Colforsin inhibits the reaction [Puromycin Aminonucleoside results in increased activity of CASP3 protein]
KT 5720 inhibits the reaction [Colforsin results in increased activity of CASP3 protein]
Colforsin inhibits the reaction [Cisplatin results in increased cleavage of and results in increased activity of CASP3 protein]
CTD PMID:16396944 PMID:20131233 PMID:21745194 PMID:31278978 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062
JBrowse link
G CAT catalase multiple interactions ISO Colforsin inhibits the reaction [mancozeb results in decreased activity of CAT protein] CTD PMID:29283200 NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060
JBrowse link
G CCL5 C-C motif chemokine ligand 5 multiple interactions ISO Colforsin inhibits the reaction [Reactive Oxygen Species results in increased expression of CCL5 mRNA]; Colforsin inhibits the reaction [TNF protein results in increased expression of CCL5 mRNA] CTD PMID:10495789 NCBI chr17:35,871,491...35,880,360
Ensembl chr17:35,871,491...35,880,793
JBrowse link
G CD55 CD55 molecule (Cromer blood group) multiple interactions
increases expression
EXP 3',4'-dimethoxy-alpha-naphthoflavone inhibits the reaction [Colforsin results in increased expression of CD55 mRNA] CTD PMID:22553215 NCBI chr 1:207,321,678...207,360,966
Ensembl chr 1:207,321,519...207,386,804
JBrowse link
G CDC6 cell division cycle 6 increases expression EXP Colforsin results in increased expression of CDC6 mRNA CTD PMID:16751804 NCBI chr17:40,287,879...40,304,657
Ensembl chr17:40,287,879...40,304,657
JBrowse link
G CDH1 cadherin 1 affects activity
decreases expression
increases expression
EXP Colforsin affects the activity of CDH1 protein
Colforsin results in decreased expression of CDH1 protein
Colforsin results in increased expression of CDH1 protein
CTD PMID:10413674 PMID:30983542 PMID:38301883 NCBI chr16:68,737,292...68,835,537
Ensembl chr16:68,737,292...68,835,537
JBrowse link
G CDRT4 CMT1A duplicated region transcript 4 multiple interactions EXP [Colforsin co-treated with Diethylhexyl Phthalate] affects the expression of CDRT4 mRNA CTD PMID:35892601 NCBI chr17:15,436,015...15,467,621
Ensembl chr17:15,436,015...15,475,728
JBrowse link
G CEBPA CCAAT enhancer binding protein alpha multiple interactions
increases expression
ISO Colforsin inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CEBPA mRNA]
Colforsin inhibits the reaction [mono-(2-ethylhexyl)phthalate results in decreased expression of CEBPA protein]
Colforsin results in increased expression of CEBPA protein
CTD PMID:17407152 PMID:21832167 NCBI chr19:33,299,934...33,302,534
Ensembl chr19:33,299,934...33,302,534
JBrowse link
G CEBPB CCAAT enhancer binding protein beta increases expression
multiple interactions
ISO Colforsin results in increased expression of CEBPB mRNA
[Atrazine co-treated with Colforsin] results in increased expression of CEBPB protein
CTD PMID:14684744 PMID:25253736 NCBI chr20:50,190,583...50,192,690
Ensembl chr20:50,190,734...50,192,690
JBrowse link
G CFTR CF transmembrane conductance regulator affects localization
multiple interactions
increases activity
EXP
ISO
Colforsin affects the localization of CFTR protein
[Colforsin co-treated with Genistein] results in increased activity of CFTR protein; AICA ribonucleotide inhibits the reaction [Colforsin results in increased activity of CFTR protein]
[1-Methyl-3-isobutylxanthine co-treated with Colforsin] results in increased activity of CFTR protein; Colforsin promotes the reaction [Nimodipine results in increased activity of CFTR protein]
3-((3-trifluoromethyl)phenyl)-5-((3-carboxyphenyl)methylene)-2-thioxo-4-thiazolidinone inhibits the reaction [[[Colforsin co-treated with Genistein] results in increased activity of CFTR protein] which results in increased transport of Iodides]; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid inhibits the reaction [Colforsin results in increased activity of CFTR protein]; 5-butyl-6-hydroxy-10-chlorobenzo(c)quinolizinium chloride inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]; 5-butyl-7-chloro-6-hydroxybenzo(c)quinolizinium inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]; 6-hydroxy-10-chlorobenzo(c)quinolizinium inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]; [1-Methyl-3-isobutylxanthine co-treated with Colforsin] results in increased activity of CFTR protein; [1-Methyl-3-isobutylxanthine co-treated with Colforsin] results in increased activity of CFTR protein mutant form; [5-butyl-6-hydroxy-10-chlorobenzo(c)quinolizinium chloride co-treated with Colforsin] results in increased activity of CFTR protein mutant form; [[Colforsin co-treated with Genistein] results in increased activity of CFTR protein] which results in increased transport of Iodides; [Colforsin co-treated with 1-Methyl-3-isobutylxanthine] results in increased activity of CFTR protein; [Colforsin co-treated with Genistein] results in increased activity of CFTR protein; [Colforsin co-treated with lumacaftor] results in increased activity of CFTR protein mutant form; [Colforsin co-treated with NS 004] results in increased activity of CFTR protein mutant form; [ivacaftor co-treated with Colforsin co-treated with lumacaftor] results in increased activity of CFTR protein mutant form; [ivacaftor co-treated with Colforsin] results in increased activity of CFTR protein; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [5-butyl-7-chloro-6-hydroxybenzo(c)quinolizinium inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [miglustat inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]]; Brefeldin A inhibits the reaction [5-butyl-7-chloro-6-hydroxybenzo(c)quinolizinium inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]]; Brefeldin A inhibits the reaction [miglustat inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]]; CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]; Colforsin binds to and results in decreased activity of CFTR protein; Colforsin promotes the reaction [CFTR protein affects the export of Chlorides]; Colforsin promotes the reaction [Nimodipine results in increased activity of CFTR protein]; Colforsin results in increased phosphorylation of and results in increased activity of CFTR protein; fenamic acid inhibits the reaction [[[Colforsin co-treated with Genistein] results in increased activity of CFTR protein] which results in increased transport of Iodides]; fenamic acid inhibits the reaction [Colforsin results in increased activity of CFTR protein]; geldanamycin promotes the reaction [5-butyl-7-chloro-6-hydroxybenzo(c)quinolizinium inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]]; geldanamycin promotes the reaction [miglustat inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]]; Glyburide inhibits the reaction [[[Colforsin co-treated with Genistein] results in increased activity of CFTR protein] which results in increased transport of Iodides]; Glyburide inhibits the reaction [Colforsin results in increased activity of CFTR protein]; miglustat inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Colforsin results in increased activity of CFTR protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Colforsin results in increased phosphorylation of CFTR protein]; Ozone inhibits the reaction [Colforsin results in increased activity of CFTR protein]; Thapsigargin promotes the reaction [5-butyl-7-chloro-6-hydroxybenzo(c)quinolizinium inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]]; Thapsigargin promotes the reaction [miglustat inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]]; VRT 532 analog promotes the reaction [Colforsin results in increased activity of CFTR protein mutant form]; VRT 532 promotes the reaction [Colforsin results in increased activity of CFTR protein mutant form]
Colforsin analog results in increased activity of CFTR protein mutant form; Colforsin results in increased activity of CFTR protein; Colforsin results in increased activity of CFTR protein mutant form
CTD PMID:12519745 PMID:12914781 PMID:14502435 PMID:14967738 PMID:15163550 More... NCBI chr 7:117,480,025...117,668,665
Ensembl chr 7:117,287,120...117,715,971
JBrowse link
G CGA glycoprotein hormones, alpha polypeptide increases secretion
increases expression
multiple interactions
EXP
ISO
Colforsin results in increased secretion of CGA protein
Colforsin results in increased expression of CGA protein
Colforsin results in increased expression of CGA mRNA
Colforsin promotes the reaction [CGA protein results in increased abundance of Cyclic AMP]; perfluorobutanesulfonic acid inhibits the reaction [Colforsin results in increased expression of CGA protein]; perfluorooctane sulfonic acid inhibits the reaction [Colforsin results in increased expression of CGA protein]
Colforsin inhibits the reaction [ESR2 gene mutant form inhibits the reaction [CGA protein results in increased abundance of Cyclic AMP]]
CTD PMID:8404651 PMID:16503475 PMID:20378682 PMID:33144174 NCBI chr 6:87,085,498...87,095,106
Ensembl chr 6:87,085,498...87,095,106
JBrowse link
G CGB1 chorionic gonadotropin subunit beta 1 increases expression
multiple interactions
increases secretion
EXP Colforsin results in increased expression of CGB1 mRNA
Valproic Acid inhibits the reaction [Colforsin results in increased expression of CGB1 mRNA]; Valproic Acid inhibits the reaction [Colforsin results in increased secretion of CGB1 protein]
CTD PMID:37385477 NCBI chr19:49,035,569...49,036,895
Ensembl chr19:49,035,569...49,036,895
JBrowse link
G CGB2 chorionic gonadotropin subunit beta 2 increases expression EXP Colforsin results in increased expression of CGB2 mRNA CTD PMID:29679653 NCBI chr19:49,031,890...49,033,238
Ensembl chr19:49,031,890...49,033,238
JBrowse link
G CGB3 chorionic gonadotropin subunit beta 3 multiple interactions
increases expression
increases secretion
EXP [Cadmium Chloride results in increased abundance of Cadmium] inhibits the reaction [Colforsin results in increased expression of CGB3 mRNA]; cobaltous chloride inhibits the reaction [Valproic Acid promotes the reaction [Colforsin results in increased expression of CGB3 mRNA]]; Colforsin promotes the reaction [Benzo(a)pyrene results in increased expression of CGB3 mRNA]; Colforsin promotes the reaction [CGB3 protein results in increased abundance of Cyclic AMP]; Flame Retardants inhibits the reaction [[CGB3 protein co-treated with Colforsin] results in increased abundance of Cyclic AMP]; Flame Retardants inhibits the reaction [Colforsin promotes the reaction [CGB3 protein results in increased abundance of Cyclic AMP]]; hexabromocyclododecane inhibits the reaction [Colforsin promotes the reaction [CGB3 protein results in increased abundance of Cyclic AMP]]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide affects the reaction [Colforsin results in increased expression of CGB3 mRNA]; Valproic Acid promotes the reaction [Colforsin results in increased expression of CGB3 mRNA]; Valproic Acid promotes the reaction [Colforsin results in increased expression of CGB3 protein]
Colforsin results in increased expression of CGB3 mRNA; Colforsin results in increased expression of CGB3 protein
Colforsin results in increased secretion of CGB3 protein
CTD PMID:23347875 PMID:24361490 PMID:35908931 PMID:38296531 NCBI chr19:49,022,869...49,024,333
Ensembl chr19:49,022,869...49,024,333
JBrowse link
G CGB7 chorionic gonadotropin subunit beta 7 multiple interactions
increases expression
EXP perfluorobutanesulfonic acid inhibits the reaction [Colforsin results in increased expression of CGB7 mRNA]; perfluorooctane sulfonic acid inhibits the reaction [Colforsin results in increased expression of CGB7 mRNA] CTD PMID:33144174 NCBI chr19:49,054,274...49,057,749
Ensembl chr19:49,054,274...49,058,860
JBrowse link
G CIDEC cell death inducing DFFA like effector c increases expression ISO Colforsin results in increased expression of CIDEC protein CTD PMID:21097823 NCBI chr 3:9,866,710...9,880,253
Ensembl chr 3:9,866,711...9,880,255
JBrowse link
G CKMT1A creatine kinase, mitochondrial 1A multiple interactions EXP [Colforsin co-treated with Diethylhexyl Phthalate] affects the expression of CKMT1A mRNA CTD PMID:35892601 NCBI chr15:43,692,786...43,699,222
Ensembl chr15:43,692,886...43,699,222
Ensembl chr15:43,692,886...43,699,222
JBrowse link
G CNR1 cannabinoid receptor 1 multiple interactions
affects response to substance
increases activity
EXP (1-(2-morpholin-4-yl-ethyl)-1H-indol-3-yl)-(2,2,3,3-tetramethylcyclopropyl)methanone inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; (1-pentyl-1H-indol-3-yl)(2,2,3,3-tetramethylcyclopropyl)methanone inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; (4-ethyl-1-naphthalenyl)(1-(5-fluoropentyl)-1H-indol-3-yl)methanone inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; 1-(2-cyclohexylethyl)-3-(2-methoxyphenylacetyl)indole inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; 1-(5-fluoropentyl)-3-(4-methyl-1-naphthoyl)indole analog inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; 1-(5-fluoropentyl)-3-(4-methyl-1-naphthoyl)indole inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; 1-(cyclohexylmethyl)-1H-indole-3-carboxylic acid 8-quinolinyl ester inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; 1-pentyfluoro-1H-indole-3-carboxylic acid 8-quinolinyl ester inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; 1-pentyl-1H-indole-3-carboxylic acid 8-quinolinyl ester inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; 1-pentyl-3-(1-naphthoyl)indole analog inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; 2-(4-methoxyphenyl)-1-(1-pentyl-indol-3-yl)methanone inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; 3-((adamantan-1-yl)carbonyl)-1-pentylindole analog inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; 3-((adamantan-1-yl)carbonyl)-1-pentylindole inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; 3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol inhibits the reaction [Colforsin results in increased activity of CNR1 protein]; [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]; [Dronabinol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]; [Medroxyprogesterone Acetate co-treated with Estradiol co-treated with Colforsin] results in increased expression of CNR1 mRNA; AM 6527 analog inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; AM 6527 inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; CNR1 protein inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]; delta(9)-tetrahydrocannabinolic acid inhibits the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol inhibits the reaction [Colforsin results in increased activity of CNR1 protein]]; delta(9)-tetrahydrocannabinolic acid inhibits the reaction [Colforsin results in increased activity of CNR1 protein]; Dronabinol inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; Dronabinol inhibits the reaction [Colforsin results in increased activity of CNR1 protein]; FDU-PB-22 inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; FUB-PB-22 compound inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; Indazoles analog inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; Indoles analog inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; N-(1-adamantyl)-1-(5-fluoropentyl)-1H-indazole-3-carboxamide inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; N-(1-adamantyl)-1-pentylindazole-3-carboxamide analog inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; N-(adamantan-1-yl)-1-(5-fluoropentyl)-1H-indole-3-carboxamide inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; N-(adamtan-1-yl)-1-pentyl-1H-indole-3-carboxamide analog inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; N-(adamtan-1-yl)-1-pentyl-1H-indole-3-carboxamide inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; N-1-naphthalenyl-1-pentyl-1H-indazole-3-carboxamide analog inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; N-1-naphthalenyl-1-pentyl-1H-indazole-3-carboxamide inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; napht-1-yl 1-(5-fluoropentyl)-1H-indole-3-carboxylate inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; THJ-2201 inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; XLR-11 analog inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; XLR-11 inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]
CNR1 protein affects the susceptibility to Colforsin
CTD PMID:27429655 PMID:27527584 PMID:28861508 PMID:31154070 NCBI chr 6:88,139,864...88,167,349
Ensembl chr 6:88,139,864...88,166,347
JBrowse link
G CNR2 cannabinoid receptor 2 multiple interactions
increases activity
affects response to substance
EXP
ISO
(1-(2-morpholin-4-yl-ethyl)-1H-indol-3-yl)-(2,2,3,3-tetramethylcyclopropyl)methanone inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; (1-pentyl-1H-indol-3-yl)(2,2,3,3-tetramethylcyclopropyl)methanone inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; (4-ethyl-1-naphthalenyl)(1-(5-fluoropentyl)-1H-indol-3-yl)methanone inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; 1-(2-cyclohexylethyl)-3-(2-methoxyphenylacetyl)indole inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; 1-(5-fluoropentyl)-3-(4-methyl-1-naphthoyl)indole analog inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; 1-(5-fluoropentyl)-3-(4-methyl-1-naphthoyl)indole inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; 1-(cyclohexylmethyl)-1H-indole-3-carboxylic acid 8-quinolinyl ester inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; 1-pentyfluoro-1H-indole-3-carboxylic acid 8-quinolinyl ester inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; 1-pentyl-1H-indole-3-carboxylic acid 8-quinolinyl ester inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; 1-pentyl-3-(1-naphthoyl)indole analog inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; 2-(4-methoxyphenyl)-1-(1-pentyl-indol-3-yl)methanone inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; 3-((adamantan-1-yl)carbonyl)-1-pentylindole analog inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; 3-((adamantan-1-yl)carbonyl)-1-pentylindole inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; 3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol inhibits the reaction [Colforsin results in increased activity of CNR2 protein]; [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased abundance of Cyclic AMP]; [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]; [Dronabinol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]; [Medroxyprogesterone Acetate co-treated with Estradiol co-treated with Colforsin] results in increased expression of CNR2 mRNA; [virodhamine binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased abundance of Cyclic AMP]; AM 6527 analog inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; AM 6527 inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; CNR2 protein inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]; Dronabinol inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; Dronabinol inhibits the reaction [Colforsin results in increased activity of CNR2 protein]; FDU-PB-22 inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; FUB-PB-22 compound inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; Indazoles analog inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; Indoles analog inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; N-(1-adamantyl)-1-(5-fluoropentyl)-1H-indazole-3-carboxamide inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; N-(1-adamantyl)-1-pentylindazole-3-carboxamide analog inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; N-(adamantan-1-yl)-1-(5-fluoropentyl)-1H-indole-3-carboxamide inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; N-(adamtan-1-yl)-1-pentyl-1H-indole-3-carboxamide analog inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; N-(adamtan-1-yl)-1-pentyl-1H-indole-3-carboxamide inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; N-1-naphthalenyl-1-pentyl-1H-indazole-3-carboxamide analog inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; N-1-naphthalenyl-1-pentyl-1H-indazole-3-carboxamide inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; napht-1-yl 1-(5-fluoropentyl)-1H-indole-3-carboxylate inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; Pertussis Toxin inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased abundance of Cyclic AMP]]; Pertussis Toxin inhibits the reaction [[virodhamine binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased abundance of Cyclic AMP]]; SR 144528 inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased abundance of Cyclic AMP]]; SR 144528 inhibits the reaction [[virodhamine binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased abundance of Cyclic AMP]]; THJ-2201 inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; XLR-11 analog inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; XLR-11 inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]
CNR2 protein affects the susceptibility to Colforsin
CTD PMID:17558435 PMID:27429655 PMID:27527584 PMID:28861508 PMID:30504240 More... NCBI chr 1:23,870,515...23,913,362
Ensembl chr 1:23,870,515...23,913,362
JBrowse link
G CREB1 cAMP responsive element binding protein 1 increases activity
increases expression
increases phosphorylation
multiple interactions
ISO
EXP
Colforsin results in increased activity of CREB1 protein
Colforsin results in increased expression of CREB1 mRNA; Colforsin results in increased expression of CREB1 protein modified form
Colforsin results in increased phosphorylation of CREB1 protein
3-(3-chloro-4-hydroxyphenylamino)-4-(4-nitrophenyl)-1H-pyrrole-2,5-dione inhibits the reaction [Resveratrol inhibits the reaction [Colforsin results in increased phosphorylation of CREB1 protein]]; Colforsin inhibits the reaction [Caffeine results in decreased expression of CREB1 mRNA]; Colforsin inhibits the reaction [Carbon Tetrachloride results in decreased expression of CREB1 protein modified form]; Colforsin promotes the reaction [CREB1 protein binds to POU1F1 promoter]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Colforsin results in increased phosphorylation of CREB1 protein]; Okadaic Acid inhibits the reaction [Resveratrol inhibits the reaction [Colforsin results in increased phosphorylation of CREB1 protein]]; Resveratrol inhibits the reaction [Colforsin promotes the reaction [CREB1 protein binds to POU1F1 promoter]]; Resveratrol inhibits the reaction [Colforsin results in increased phosphorylation of CREB1 protein]; SIRT1 mutant form inhibits the reaction [Resveratrol inhibits the reaction [Colforsin results in increased phosphorylation of CREB1 protein]]; SIRT1 protein inhibits the reaction [Colforsin results in increased phosphorylation of CREB1 protein]; SIRT1 protein mutant form inhibits the reaction [Colforsin results in increased phosphorylation of CREB1 protein]
AKAP13 protein modified form inhibits the reaction [Colforsin results in increased phosphorylation of CREB1 protein]; anandamide inhibits the reaction [Colforsin results in increased phosphorylation of CREB1 protein]; Colforsin inhibits the reaction [anandamide inhibits the reaction [CREB1 protein modified form binds to ABCG2 promoter]]; Colforsin results in increased phosphorylation of and results in increased activity of CREB1 protein
[Colforsin co-treated with 1-Methyl-3-isobutylxanthine] results in increased phosphorylation of CREB1 protein; alisol B inhibits the reaction [[Colforsin co-treated with 1-Methyl-3-isobutylxanthine] results in increased phosphorylation of CREB1 protein]; oxophenylarsine inhibits the reaction [Colforsin results in increased activity of CREB1 protein]; oxophenylarsine inhibits the reaction [Colforsin results in increased phosphorylation of CREB1 protein]; RTKI cpd inhibits the reaction [Colforsin results in increased phosphorylation of CREB1 protein]
CTD PMID:10908723 PMID:11113530 PMID:15522277 PMID:17141199 PMID:17322281 More... NCBI chr 2:207,529,962...207,605,988
Ensembl chr 2:207,529,737...207,605,988
JBrowse link
G CREBBP CREB binding protein multiple interactions EXP Colforsin promotes the reaction [GCM1 protein binds to CREBBP protein]; CREBBP protein affects the reaction [Colforsin results in increased activity of GCM1 protein] CTD PMID:16166624 NCBI chr16:3,725,054...3,880,713
Ensembl chr16:3,725,054...3,880,713
JBrowse link
G CREM cAMP responsive element modulator increases expression ISO Colforsin results in increased expression of CREM mRNA; Colforsin results in increased expression of CREM mRNA alternative form; Colforsin results in increased expression of CREM protein CTD PMID:8810303 PMID:12791704 NCBI chr10:35,126,846...35,212,958
Ensembl chr10:35,126,791...35,212,958
JBrowse link
G CRH corticotropin releasing hormone multiple interactions
increases secretion
ISO
EXP
CRH protein inhibits the reaction [[Colforsin co-treated with CGB3 protein] results in increased chemical synthesis of Cyclic AMP]; CRH protein inhibits the reaction [[Colforsin co-treated with CGB3 protein] results in increased chemical synthesis of Testosterone]; CRH protein inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]; CRH protein inhibits the reaction [Colforsin results in increased chemical synthesis of Testosterone]
[perfluorooctane sulfonic acid co-treated with Colforsin] results in increased expression of CRH mRNA
Colforsin results in increased secretion of CRH protein
CTD PMID:2153673 PMID:33144174 NCBI chr 8:66,176,376...66,178,464
Ensembl chr 8:66,176,376...66,178,464
JBrowse link
G CRLS1 cardiolipin synthase 1 increases expression EXP Colforsin results in increased expression of CRLS1 mRNA CTD PMID:16751804 NCBI chr20:6,005,938...6,040,053
Ensembl chr20:6,006,093...6,040,053
JBrowse link
G CRYAB crystallin alpha B multiple interactions ISO Colforsin inhibits the reaction [arsenite results in increased expression of CRYAB protein] CTD PMID:8769853 NCBI chr11:111,908,564...111,923,740
Ensembl chr11:111,908,564...111,923,722
JBrowse link
G CSH1 chorionic somatomammotropin hormone 1 decreases expression
multiple interactions
EXP Colforsin results in decreased expression of CSH1 mRNA
[Valproic Acid co-treated with Colforsin] results in decreased expression of CSH1 mRNA; [Valproic Acid co-treated with Colforsin] results in decreased expression of CSH1 protein; cobaltous chloride promotes the reaction [Valproic Acid promotes the reaction [Colforsin results in decreased expression of CSH1 mRNA]]; Valproic Acid promotes the reaction [Colforsin results in decreased expression of CSH1 mRNA]
CTD PMID:29679653 PMID:38296531 NCBI chr17:63,894,918...63,896,574
Ensembl chr17:63,894,909...63,896,661
JBrowse link
G CSH2 chorionic somatomammotropin hormone 2 decreases expression EXP Colforsin results in decreased expression of CSH2 mRNA CTD PMID:37385477 NCBI chr17:63,872,012...63,873,729
Ensembl chr17:63,872,012...63,873,766
JBrowse link
G CXCL8 C-X-C motif chemokine ligand 8 multiple interactions ISO
EXP
Colforsin promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CXCL15 mRNA]
[Colforsin results in increased activity of AHR protein] which results in increased expression of CXCL8 mRNA; [Colforsin results in increased activity of AHR protein] which results in increased expression of CXCL8 protein; [Colforsin results in increased activity of AHR protein] which results in increased secretion of CXCL8 protein; [nickel sulfate co-treated with Colforsin] results in increased secretion of CXCL8 protein; Colforsin promotes the reaction [[AHR protein binds to RELB protein] which binds to CXCL8 promoter]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Colforsin promotes the reaction [[AHR protein binds to RELB protein] which binds to CXCL8 promoter]]
CTD PMID:17823304 PMID:19063610 PMID:23526216 NCBI chr 4:73,740,569...73,743,716
Ensembl chr 4:73,740,519...73,743,716
JBrowse link
G CYP11A1 cytochrome P450 family 11 subfamily A member 1 affects expression
multiple interactions
increases expression
EXP
ISO
Colforsin affects the expression of CYP11A1 mRNA
[Colforsin co-treated with Zearalenone] results in increased expression of CYP11A1 mRNA
Colforsin results in increased expression of CYP11A1 mRNA
[Colforsin co-treated with triptolide] results in decreased expression of CYP11A1 mRNA; Aminoglutethimide inhibits the reaction [Colforsin results in increased expression of CYP11A1 mRNA]; BMP6 protein inhibits the reaction [Colforsin results in increased expression of CYP11A1 mRNA]; Hexachlorocyclohexane inhibits the reaction [Colforsin results in increased expression of CYP11A1 mRNA]; Metyrapone inhibits the reaction [Colforsin results in increased expression of CYP11A1 mRNA]; Valproic Acid affects the reaction [Colforsin affects the expression of CYP11A1 mRNA]
[Atrazine co-treated with Colforsin] results in increased expression of CYP11A1 mRNA; RARRES2 protein inhibits the reaction [Colforsin results in increased expression of CYP11A1 protein]
CTD PMID:14691014 PMID:16935330 PMID:17080404 PMID:18936084 PMID:20726872 More... NCBI chr15:74,337,762...74,367,646
Ensembl chr15:74,337,759...74,367,646
JBrowse link
G CYP11B1 cytochrome P450 family 11 subfamily B member 1 increases activity
increases expression
multiple interactions
EXP Colforsin results in increased activity of CYP11B1 protein
Colforsin results in increased expression of CYP11B1 mRNA
[1-chloro-4-(2,2-dichloro-1-(4-chlorophenyl)ethenyl)-3-(methylsulfonyl)benzene co-treated with Colforsin] affects the expression of CYP11B1 mRNA; [Colforsin co-treated with triptolide] results in decreased expression of CYP11B1 mRNA; Hexachlorocyclohexane inhibits the reaction [Colforsin results in increased expression of CYP11B1 mRNA]
CTD PMID:12525251 PMID:17080404 PMID:19164467 PMID:19900470 PMID:21256172 More... NCBI chr 8:142,872,357...142,879,825
Ensembl chr 8:142,872,356...142,879,846
JBrowse link
G CYP11B2 cytochrome P450 family 11 subfamily B member 2 increases expression
multiple interactions
EXP Colforsin results in increased expression of CYP11B2 mRNA
[1-chloro-4-(2,2-dichloro-1-(4-chlorophenyl)ethenyl)-3-(methylsulfonyl)benzene co-treated with Colforsin] affects the expression of CYP11B2 mRNA; [Colforsin co-treated with triptolide] results in decreased expression of CYP11B2 mRNA; Hexachlorocyclohexane inhibits the reaction [Colforsin results in increased expression of CYP11B2 mRNA]; Ketoconazole promotes the reaction [Colforsin results in increased expression of CYP11B2 mRNA]
CTD PMID:16935330 PMID:17080404 PMID:19164467 PMID:19900470 PMID:21256172 More... NCBI chr 8:142,910,559...142,917,843
Ensembl chr 8:142,910,559...142,917,843
JBrowse link
G CYP17A1 cytochrome P450 family 17 subfamily A member 1 increases expression
multiple interactions
ISO
EXP
Colforsin results in increased expression of CYP17A1 mRNA
[Colforsin co-treated with triptolide] results in decreased expression of CYP17A1 mRNA; Apigenin inhibits the reaction [Colforsin results in increased expression of CYP17A1 mRNA]; Hexachlorocyclohexane inhibits the reaction [Colforsin results in increased expression of CYP17A1 mRNA]; Ketoconazole inhibits the reaction [Colforsin results in increased expression of CYP17A1 mRNA]; Metyrapone inhibits the reaction [Colforsin results in increased expression of CYP17A1 mRNA]; TGFB1 protein inhibits the reaction [Colforsin results in increased expression of CYP17A1 mRNA]; Valproic Acid inhibits the reaction [Colforsin results in increased expression of CYP17A1 mRNA]
CTD PMID:15625562 PMID:15886251 PMID:16935330 PMID:17080404 PMID:20726872 More... NCBI chr10:102,830,531...102,837,413
Ensembl chr10:102,830,531...102,837,472
JBrowse link
G CYP19A1 cytochrome P450 family 19 subfamily A member 1 increases activity
increases expression
multiple interactions
EXP
ISO
Colforsin results in increased activity of CYP19A1 protein
Colforsin results in increased expression of CYP19A1 mRNA
1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [Colforsin results in increased expression of CYP19A1 mRNA]; [Colforsin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CYP19A1 mRNA; [Colforsin results in increased activity of CYP19A1 protein] which results in increased abundance of Estradiol; [Colforsin results in increased activity of CYP19A1 protein] which results in increased abundance of Testosterone; Alitretinoin inhibits the reaction [NR5A2 protein promotes the reaction [[Colforsin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CYP19A1 mRNA]]; Aminoglutethimide inhibits the reaction [Colforsin results in increased expression of CYP19A1 mRNA]; Atrazine inhibits the reaction [Colforsin results in increased expression of CYP19A1 mRNA]; BMP6 protein inhibits the reaction [Colforsin results in increased expression of CYP19A1 mRNA]; Hexachlorocyclohexane inhibits the reaction [Colforsin results in increased expression of CYP19A1 mRNA]; mono-(2-ethylhexyl)phthalate inhibits the reaction [Colforsin results in increased expression of CYP19A1 mRNA]; NR4A1 protein inhibits the reaction [Colforsin results in increased expression of CYP19A1 mRNA]; NR4A2 protein inhibits the reaction [Colforsin results in increased expression of CYP19A1 mRNA]; NR4A3 protein inhibits the reaction [Colforsin results in increased expression of CYP19A1 mRNA]; NR5A2 protein promotes the reaction [[Colforsin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CYP19A1 mRNA]; Valproic Acid inhibits the reaction [Colforsin results in increased activity of CYP19A1 protein]; Valproic Acid inhibits the reaction [Colforsin results in increased expression of CYP19A1 mRNA]; ZNF461 protein inhibits the reaction [Colforsin results in increased expression of CYP19A1 mRNA]
RARRES2 protein inhibits the reaction [Colforsin results in increased expression of CYP19A1 protein]
Colforsin results in increased expression of CYP19A1 mRNA; Colforsin results in increased expression of CYP19A1 protein
CTD PMID:14691014 PMID:16357189 PMID:16935330 PMID:16996190 PMID:17080404 More... NCBI chr15:51,208,057...51,338,596
Ensembl chr15:51,208,057...51,338,601
JBrowse link
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 multiple interactions
affects expression
ISO
EXP
Colforsin inhibits the reaction [Lipopolysaccharides results in decreased activity of CYP1A1 protein]
Valproic Acid affects the reaction [Colforsin affects the expression of CYP1A1 mRNA]
Colforsin affects the reaction [Benzo(a)pyrene results in increased expression of CYP1A1 mRNA]
CTD PMID:1849469 PMID:15710352 PMID:20726872 NCBI chr15:74,719,542...74,725,528
Ensembl chr15:74,719,542...74,725,536
JBrowse link
G CYP1A2 cytochrome P450 family 1 subfamily A member 2 multiple interactions ISO Colforsin affects the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 mRNA]
Colforsin inhibits the reaction [Lipopolysaccharides results in decreased activity of CYP1A2 protein]
CTD PMID:1849469 PMID:15710352 NCBI chr15:74,748,845...74,756,607
Ensembl chr15:74,748,845...74,756,607
JBrowse link
G CYP1B1 cytochrome P450 family 1 subfamily B member 1 increases expression ISO Colforsin results in increased expression of CYP1B1 mRNA; Colforsin results in increased expression of CYP1B1 protein CTD PMID:7588239 NCBI chr 2:38,067,509...38,076,151
Ensembl chr 2:38,066,973...38,109,902
JBrowse link
G CYP21A2 cytochrome P450 family 21 subfamily A member 2 multiple interactions
increases expression
EXP [Colforsin co-treated with Ketoconazole] results in decreased expression of CYP21A2 mRNA; [Colforsin co-treated with triptolide] results in decreased expression of CYP21A2 mRNA; Apigenin inhibits the reaction [Colforsin results in increased expression of CYP21A2 mRNA]; daidzein inhibits the reaction [Colforsin results in increased expression of CYP21A2 mRNA]; Valproic Acid inhibits the reaction [Colforsin results in increased expression of CYP21A2 mRNA] CTD PMID:16935330 PMID:20726872 PMID:21256172 PMID:22446829 PMID:23370353 More... NCBI chr 6:32,038,415...32,041,644
Ensembl chr 6:32,038,327...32,041,644
JBrowse link
G CYP2A6 cytochrome P450 family 2 subfamily A member 6 increases expression ISO Colforsin results in increased expression of CYP2A5 mRNA CTD PMID:11162586 NCBI chr19:40,843,541...40,850,447
Ensembl chr19:40,843,541...40,850,447
JBrowse link
G CYP2E1 cytochrome P450 family 2 subfamily E member 1 multiple interactions EXP [S-(1,2-dichlorovinyl)cysteine co-treated with Colforsin] results in decreased expression of CYP2E1 mRNA CTD PMID:37544576 NCBI chr10:133,527,363...133,539,123
Ensembl chr10:133,520,406...133,561,220
JBrowse link
G CYP3A4 cytochrome P450 family 3 subfamily A member 4 multiple interactions
increases expression
EXP [S-(1,2-dichlorovinyl)cysteine co-treated with Colforsin] results in increased expression of CYP3A4 mRNA
Colforsin results in increased expression of CYP3A4 mRNA
CTD PMID:37544576 NCBI chr 7:99,756,967...99,784,184
Ensembl chr 7:99,756,960...99,784,248
JBrowse link
G DBH dopamine beta-hydroxylase multiple interactions
increases expression
ISO Colforsin inhibits the reaction [Atrazine results in decreased expression of DBH protein]; Colforsin inhibits the reaction [Simazine results in decreased expression of DBH protein]
Colforsin results in increased expression of DBH protein
CTD PMID:14550852 NCBI chr 9:133,636,363...133,659,329
Ensembl chr 9:133,636,363...133,659,329
JBrowse link
G DCT dopachrome tautomerase increases expression EXP Colforsin results in increased expression of DCT mRNA; Colforsin results in increased expression of DCT protein CTD PMID:17460731 PMID:28601556 NCBI chr13:94,436,811...94,549,406
Ensembl chr13:94,436,811...94,479,682
JBrowse link
G DIO2 iodothyronine deiodinase 2 increases activity
multiple interactions
increases expression
ISO Colforsin results in increased activity of DIO2 protein
Buthionine Sulfoximine inhibits the reaction [Colforsin results in increased activity of DIO2 protein]; Hydrogen Peroxide inhibits the reaction [Colforsin results in increased activity of DIO2 protein]; Hydrogen Peroxide inhibits the reaction [Colforsin results in increased expression of DIO2 mRNA]; Sodium Selenite inhibits the reaction [Hydrogen Peroxide inhibits the reaction [Colforsin results in increased activity of DIO2 protein]]; U 0126 inhibits the reaction [Hydrogen Peroxide inhibits the reaction [Colforsin results in increased activity of DIO2 protein]]; U 0126 inhibits the reaction [Hydrogen Peroxide inhibits the reaction [Colforsin results in increased expression of DIO2 mRNA]]
CTD PMID:18420745 PMID:19036883 NCBI chr14:80,197,526...80,231,057
Ensembl chr14:80,197,526...80,387,757
JBrowse link
G DIO3 iodothyronine deiodinase 3 multiple interactions ISO Colforsin promotes the reaction [Hydrogen Peroxide results in increased expression of DIO3 mRNA] CTD PMID:18420745 NCBI chr14:101,561,495...101,563,452
Ensembl chr14:101,560,139...101,563,452
JBrowse link
G DNM1L dynamin 1 like decreases expression
multiple interactions
EXP Colforsin results in decreased expression of DNM1L protein
PINK1 protein affects the reaction [Colforsin results in decreased expression of DNM1L protein]
CTD PMID:24792327 NCBI chr12:32,679,301...32,745,650
Ensembl chr12:32,679,200...32,745,650
JBrowse link
G DRD2 dopamine receptor D2 multiple interactions EXP [Quinpirole binds to and results in increased activity of DRD2 protein] inhibits the reaction [Colforsin results in increased abundance of Cyclic AMP]; epigallocatechin gallate inhibits the reaction [[Quinpirole binds to and results in increased activity of DRD2 protein] inhibits the reaction [Colforsin results in increased abundance of Cyclic AMP]] CTD PMID:17958328 NCBI chr11:113,409,605...113,475,398
Ensembl chr11:113,409,605...113,475,691
JBrowse link
G DYNLL2 dynein light chain LC8-type 2 increases expression EXP Colforsin results in increased expression of DYNLL2 mRNA CTD PMID:16751804 NCBI chr17:58,083,419...58,095,542
Ensembl chr17:58,083,419...58,095,542
JBrowse link
G EDN1 endothelin 1 multiple interactions EXP Colforsin inhibits the reaction [EDN1 protein results in increased expression of CALCRL mRNA]; Colforsin inhibits the reaction [EDN1 protein results in increased expression of ICAM2 mRNA] CTD PMID:25194819 NCBI chr 6:12,230,516...12,297,194
Ensembl chr 6:12,290,361...12,297,194
JBrowse link
G EGF epidermal growth factor multiple interactions EXP [EGF co-treated with Colforsin co-treated with Rotenone] results in increased expression of HSPD1 mRNA; [EGF co-treated with Colforsin co-treated with Rotenone] results in increased expression of SOD1 mRNA; [EGF co-treated with Colforsin co-treated with Rotenone] results in increased expression of SOD1 protein; [EGF co-treated with Colforsin co-treated with Rotenone] results in increased expression of SOD2 mRNA; [EGF co-treated with Colforsin co-treated with Rotenone] results in increased expression of SOD2 protein; Acetylcysteine inhibits the reaction [[EGF co-treated with Colforsin co-treated with Rotenone] results in increased expression of HSPD1 mRNA]; Acetylcysteine inhibits the reaction [[EGF co-treated with Colforsin co-treated with Rotenone] results in increased expression of SOD1 mRNA]; Acetylcysteine inhibits the reaction [[EGF co-treated with Colforsin co-treated with Rotenone] results in increased expression of SOD1 protein]; Acetylcysteine inhibits the reaction [[EGF co-treated with Colforsin co-treated with Rotenone] results in increased expression of SOD2 mRNA]; Acetylcysteine inhibits the reaction [[EGF co-treated with Colforsin co-treated with Rotenone] results in increased expression of SOD2 protein] CTD PMID:32092105 NCBI chr 4:109,912,883...110,013,766
Ensembl chr 4:109,912,883...110,013,766
JBrowse link
G EGR1 early growth response 1 decreases expression
multiple interactions
EXP Colforsin results in decreased expression of EGR1 mRNA; Colforsin results in decreased expression of EGR1 protein
Colforsin inhibits the reaction [Ethanol results in increased expression of EGR1 mRNA]; Colforsin inhibits the reaction [Ethanol results in increased expression of EGR1 protein]; Ethanol inhibits the reaction [Colforsin results in decreased expression of EGR1 mRNA]; Ethanol inhibits the reaction [Colforsin results in decreased expression of EGR1 protein]
CTD PMID:29802914 NCBI chr 5:138,465,479...138,469,303
Ensembl chr 5:138,465,479...138,469,303
JBrowse link
G EIF2B5 eukaryotic translation initiation factor 2B subunit epsilon increases expression EXP Colforsin results in increased expression of EIF2B5 mRNA CTD PMID:16751804 NCBI chr 3:184,135,358...184,145,311
Ensembl chr 3:184,135,038...184,146,127
JBrowse link
G EIF3CL eukaryotic translation initiation factor 3 subunit C like multiple interactions EXP [Colforsin co-treated with Diethylhexyl Phthalate] affects the expression of EIF3CL mRNA CTD PMID:35892601 NCBI chr16:28,379,581...28,426,418
Ensembl chr16:28,379,579...28,403,841
JBrowse link
G EIF5A2 eukaryotic translation initiation factor 5A2 decreases expression EXP Colforsin results in decreased expression of EIF5A2 mRNA CTD PMID:30983542 NCBI chr 3:170,888,418...170,908,637
Ensembl chr 3:170,888,418...170,908,644
JBrowse link
G EPHX1 epoxide hydrolase 1 affects expression
multiple interactions
EXP Colforsin affects the expression of EPHX1 mRNA
Valproic Acid affects the reaction [Colforsin affects the expression of EPHX1 mRNA]
CTD PMID:20726872 NCBI chr 1:225,810,124...225,845,563
Ensembl chr 1:225,810,124...225,845,563
JBrowse link
G EPS8 EGFR pathway substrate 8, signaling adaptor decreases expression EXP Colforsin results in decreased expression of EPS8 mRNA CTD PMID:15313392 PMID:15967414 NCBI chr12:15,620,134...15,789,388
Ensembl chr12:15,620,134...15,882,329
JBrowse link
G EREG epiregulin increases expression EXP
ISO
Colforsin results in increased expression of EREG mRNA CTD PMID:15313392 PMID:15474502 PMID:15967414 PMID:20378682 NCBI chr 4:74,365,145...74,388,749
Ensembl chr 4:74,365,145...74,388,749
JBrowse link
G ERVFRD-1 endogenous retrovirus group FRD member 1, envelope multiple interactions
increases expression
increases secretion
EXP [Cadmium Chloride results in increased abundance of Cadmium] inhibits the reaction [Colforsin results in increased expression of ERVFRD-1 mRNA]; Colforsin promotes the reaction [Benzo(a)pyrene results in increased expression of ERVFRD-1 mRNA]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide affects the reaction [Colforsin results in increased expression of ERVFRD-1 mRNA]; Valproic Acid inhibits the reaction [Colforsin results in increased expression of ERVFRD-1 mRNA]
Colforsin results in increased expression of ERVFRD-1 mRNA; Colforsin results in increased expression of ERVFRD-1 protein
Colforsin results in increased secretion of ERVFRD-1 protein
CTD PMID:24361490 PMID:29679653 PMID:31278978 PMID:33144174 PMID:35908931 More... NCBI chr 6:11,102,489...11,111,725
Ensembl chr 6:11,102,324...11,111,845
JBrowse link
G ERVW-1 endogenous retrovirus group W member 1, envelope multiple interactions
increases expression
EXP [Colforsin co-treated with Sertraline] results in increased expression of ERVW-1 mRNA; Valproic Acid inhibits the reaction [Colforsin results in increased expression of ERVW-1 mRNA]
Colforsin results in increased expression of ERVW-1 mRNA; Colforsin results in increased expression of ERVW-1 protein
CTD PMID:29679653 PMID:31278978 PMID:33144174 PMID:36336211 PMID:37385477 NCBI chr 7:92,468,380...92,477,946
Ensembl chr 7:92,468,380...92,477,986
JBrowse link
G ESR1 estrogen receptor 1 decreases expression EXP Colforsin results in decreased expression of ESR1 mRNA CTD PMID:31278978 NCBI chr 6:151,656,672...152,129,619
Ensembl chr 6:151,656,691...152,129,619
JBrowse link
G ESR2 estrogen receptor 2 multiple interactions
decreases expression
ISO
EXP
Colforsin inhibits the reaction [ESR2 gene mutant form inhibits the reaction [CGA protein results in increased abundance of Cyclic AMP]]
Colforsin results in decreased expression of ESR2 mRNA
CTD PMID:20378682 PMID:31278978 NCBI chr14:64,226,707...64,338,613
Ensembl chr14:64,084,232...64,338,112
JBrowse link
G ESRRA estrogen related receptor alpha increases expression EXP Colforsin results in increased expression of ESRRA mRNA; Colforsin results in increased expression of ESRRA protein CTD PMID:20351196 NCBI chr11:64,305,524...64,316,743
Ensembl chr11:64,305,497...64,316,743
JBrowse link
G EVI5 ecotropic viral integration site 5 increases expression EXP Colforsin results in increased expression of EVI5 mRNA CTD PMID:16751804 NCBI chr 1:92,508,696...92,792,410
Ensembl chr 1:92,508,696...92,792,404
JBrowse link
G F2 coagulation factor II, thrombin multiple interactions EXP Colforsin inhibits the reaction [F2 protein results in increased uptake of Manganese] CTD PMID:2125206 NCBI chr11:46,719,213...46,739,506
Ensembl chr11:46,719,196...46,739,506
JBrowse link
G F2R coagulation factor II thrombin receptor multiple interactions ISO [C186 65 binds to and results in increased activity of F2R protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP] CTD PMID:22207716 NCBI chr 5:76,716,126...76,735,770
Ensembl chr 5:76,716,126...76,735,770
JBrowse link
G F2RL3 F2R like thrombin or trypsin receptor 3 multiple interactions ISO [GYPGKF-NH(2) binds to and results in increased activity of F2RL3 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP] CTD PMID:22207716 NCBI chr19:16,888,999...16,892,606
Ensembl chr19:16,888,999...16,892,606
JBrowse link
G FADS1 fatty acid desaturase 1 increases expression EXP Colforsin results in increased expression of FADS1 mRNA CTD PMID:16751804 NCBI chr11:61,799,627...61,817,003
Ensembl chr11:61,799,627...61,829,318
JBrowse link
G FASN fatty acid synthase multiple interactions EXP [Colforsin co-treated with 6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime] results in increased expression of FASN mRNA; [Colforsin co-treated with Leflunomide] results in increased expression of FASN mRNA; [Colforsin co-treated with teriflunomide] results in increased expression of FASN mRNA CTD PMID:30364229 NCBI chr17:82,078,338...82,098,236
Ensembl chr17:82,078,338...82,098,294