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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:metixene
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Accession:CHEBI:51024 term browser browse the term
Definition:A thioxanthene that has formula C20H23NS.
Synonyms:exact_synonym: 1-methyl-3-(9H-thioxanthen-9-ylmethyl)piperidine
 related_synonym: Formula=C20H23NS;   InChI=1S/C20H23NS/c1-21-12-6-7-15(14-21)13-18-16-8-2-4-10-19(16)22-20-11-5-3-9-17(18)20/h2-5,8-11,15,18H,6-7,12-14H2,1H3;   InChIKey=MJFJKKXQDNNUJF-UHFFFAOYSA-N;   Methixen;   Metisene;   SMILES=CN1CCCC(CC2c3ccccc3Sc3ccccc23)C1;   metixeno;   metixenum
 xref: Beilstein:267181;   CAS:4969-02-2;   DrugBank:DB00340;   Drug_Central:1780;   LINCS:LSM-1467
 xref_mesh: MESH:C005111
 xref: Wikipedia:Metixene


show annotations for term's descendants           Sort by:
metixene term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity ISO methixene results in decreased activity of KCNH2 protein CTD PMID:28551711 NCBI chr 4:10,826,834...10,859,009
Ensembl chr 4:10,826,928...10,859,008 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19899
    role 19869
      biological role 19867
        pharmacological role 19101
          antagonist 17266
            histamine antagonist 4895
              metixene 1
                methixene hydrochloride 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19899
    subatomic particle 19897
      composite particle 19897
        hadron 19897
          baryon 19897
            nucleon 19897
              atomic nucleus 19897
                atom 19897
                  main group element atom 19835
                    p-block element atom 19835
                      carbon group element atom 19776
                        carbon atom 19772
                          organic molecular entity 19772
                            organic molecule 19724
                              organic cyclic compound 19514
                                organic heterocyclic compound 18893
                                  organic heteropolycyclic compound 18320
                                    organic heterotricyclic compound 15876
                                      thioxanthenes 197
                                        metixene 1
                                          methixene hydrochloride 0
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