CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: fixative
Accession: CHEBI:50913
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Definition: Any compound used for the purpose of preserving biological tissues from decay in such a way as to allow for the preparation of thin, stained sections for subsequent histological study.
Synonyms: related_synonym: fixating agent; fixating agents; fixation agent
xref: Wikipedia:Fixation_(histology)
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Akr1c2
aldo-keto reductase family 1, member C2
increases expression
ISO
benzyl cinnamate results in increased expression of AKR1C2 mRNA
CTD
PMID:20491607
NCBI chr17:65,759,778...65,808,013
Ensembl chr17:65,759,788...65,775,764
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Cd86
CD86 molecule
increases expression
ISO
benzyl cinnamate results in increased expression of CD86 protein
CTD
PMID:29540657
NCBI chr11:64,142,193...64,200,816
Ensembl chr11:64,163,828...64,200,818
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Cyp1a1
cytochrome P450, family 1, subfamily a, polypeptide 1
increases expression
ISO
benzyl cinnamate results in increased expression of CYP1A1 mRNA
CTD
PMID:20491607
NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
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Maff
MAF bZIP transcription factor F
increases expression
ISO
benzyl cinnamate results in increased expression of MAFF mRNA
CTD
PMID:20491607
NCBI chr 7:110,912,367...110,923,711
Ensembl chr 7:110,912,499...110,923,851
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Maoa
monoamine oxidase A
decreases activity
ISO
benzyl cinnamate results in decreased activity of MAOA protein
CTD
PMID:27270453
NCBI chr X:6,032,172...6,098,308
Ensembl chr X:6,030,795...6,099,593
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Maob
monoamine oxidase B
decreases activity
ISO
benzyl cinnamate results in decreased activity of MAOB protein
CTD
PMID:27270453
NCBI chr X:5,907,327...6,010,996
Ensembl chr X:5,907,266...6,011,003
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Mt1
metallothionein 1
increases expression
ISO
benzyl cinnamate results in increased expression of MT1A mRNA
CTD
PMID:20491607
NCBI chr19:10,826,032...10,827,048
Ensembl chr19:10,826,032...10,827,049 Ensembl chr17:10,826,032...10,827,049
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Mt2A
metallothionein 2A
increases expression
ISO
benzyl cinnamate results in increased expression of MT2A mRNA
CTD
PMID:20491607
NCBI chr19:10,832,009...10,832,783
Ensembl chr19:10,832,002...10,832,784
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Nqo1
NAD(P)H quinone dehydrogenase 1
increases expression
ISO
benzyl cinnamate results in increased expression of NQO1 mRNA
CTD
PMID:20491607
NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
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Txn1
thioredoxin 1
increases expression
ISO
benzyl cinnamate results in increased expression of TXN mRNA
CTD
PMID:20491607
NCBI chr 5:72,712,334...72,724,564
Ensembl chr 5:72,711,933...72,724,629
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Atf4
activating transcription factor 4
increases expression
ISO
Glutaral results in increased expression of ATF4 mRNA
CTD
PMID:28236482
NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446
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Casp8
caspase 8
decreases expression
ISO
Glutaral results in decreased expression of CASP8 mRNA
CTD
PMID:28236482
NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
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Ccl4
C-C motif chemokine ligand 4
increases expression
ISO
Glutaral results in increased expression of CCL4 mRNA
CTD
PMID:20713136
NCBI chr10:68,466,394...68,468,229
Ensembl chr10:68,452,052...68,468,231
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Cd86
CD86 molecule
increases expression
ISO
Glutaral results in increased expression of CD86 protein
CTD
PMID:19665512
NCBI chr11:64,142,193...64,200,816
Ensembl chr11:64,163,828...64,200,818
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G6pd
glucose-6-phosphate dehydrogenase
decreases activity
ISO
Glutaral results in decreased activity of G6PD protein
CTD
PMID:19490936
NCBI chr X:152,201,081...152,220,863
Ensembl chr X:152,201,098...152,220,801
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Gja1
gap junction protein, alpha 1
decreases expression
EXP
Glutaral results in decreased expression of GJA1 protein
CTD
PMID:19932693
NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582
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Gsr
glutathione-disulfide reductase
decreases activity multiple interactions
ISO
Glutaral results in decreased activity of GSR protein Idarubicin promotes the reaction [Glutaral results in decreased activity of GSR protein]
CTD
PMID:19490936
NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
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Il1r2
interleukin 1 receptor type 2
increases expression
ISO
Glutaral results in increased expression of IL1R2 mRNA
CTD
PMID:20713136
NCBI chr 9:42,384,280...42,424,726
Ensembl chr 9:42,384,433...42,424,725
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Il6
interleukin 6
affects expression
ISO
Glutaral affects the expression of IL6 mRNA
CTD
PMID:20200221
NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
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Muc1
mucin 1, cell surface associated
decreases expression increases expression
ISO
Glutaral results in decreased expression of MUC1 protein Glutaral results in increased expression of MUC1 protein
CTD
PMID:38360295
NCBI chr 2:174,635,989...174,640,738
Ensembl chr 2:174,635,995...174,640,733
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Pmaip1
phorbol-12-myristate-13-acetate-induced protein 1
increases expression
ISO
Glutaral results in increased expression of PMAIP1 mRNA
CTD
PMID:20713136
NCBI chr18:59,986,020...59,992,434
Ensembl chr18:59,986,017...59,992,429
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Tnf
tumor necrosis factor
affects expression increases expression
ISO
Glutaral affects the expression of TNF mRNA Glutaral results in increased expression of TNF mRNA
CTD
PMID:20200221 PMID:28236482
NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
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Tp53
tumor protein p53
decreases expression
ISO
Glutaral results in decreased expression of TP53 mRNA
CTD
PMID:28236482
NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
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Fth1
ferritin heavy chain 1
multiple interactions decreases expression
ISO
GDF11 protein promotes the reaction [sodium bisulfide inhibits the reaction [paraform results in decreased expression of FTH1 protein]]; sodium bisulfide inhibits the reaction [paraform results in decreased expression of FTH1 protein]
CTD
PMID:37105376
NCBI chr 1:206,627,142...206,629,430
Ensembl chr 1:206,627,103...206,725,424
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Gdf11
growth differentiation factor 11
multiple interactions increases expression
ISO
GDF11 protein inhibits the reaction [Hydrogen Sulfide inhibits the reaction [paraform results in decreased expression of SQSTM1 protein]]; GDF11 protein promotes the reaction [sodium bisulfide inhibits the reaction [paraform results in decreased expression of FTH1 protein]]; GDF11 protein promotes the reaction [sodium bisulfide inhibits the reaction [paraform results in increased expression of MAP1LC3B protein]]; GDF11 protein promotes the reaction [sodium bisulfide inhibits the reaction [paraform results in increased expression of NCOA1 protein]]; sodium bisulfide inhibits the reaction [paraform results in increased expression of GDF11 protein]
CTD
PMID:37105376
NCBI chr 7:1,311,732...1,325,211
Ensembl chr 7:1,311,732...1,320,725
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Map1lc3b
microtubule-associated protein 1 light chain 3 beta
multiple interactions increases expression
ISO
GDF11 protein promotes the reaction [sodium bisulfide inhibits the reaction [paraform results in increased expression of MAP1LC3B protein]]; sodium bisulfide inhibits the reaction [paraform results in increased expression of MAP1LC3B protein]
CTD
PMID:37105376
NCBI chr19:49,665,795...49,673,655
Ensembl chr19:49,665,791...49,677,690
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Ncoa1
nuclear receptor coactivator 1
increases expression multiple interactions
ISO
paraform results in increased expression of NCOA1 protein GDF11 protein promotes the reaction [sodium bisulfide inhibits the reaction [paraform results in increased expression of NCOA1 protein]]; sodium bisulfide inhibits the reaction [paraform results in increased expression of NCOA1 protein]
CTD
PMID:37105376
NCBI chr 6:27,232,609...27,507,992
Ensembl chr 6:27,232,611...27,475,664
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Sqstm1
sequestosome 1
multiple interactions decreases expression
ISO
GDF11 protein inhibits the reaction [Hydrogen Sulfide inhibits the reaction [paraform results in decreased expression of SQSTM1 protein]]; Hydrogen Sulfide inhibits the reaction [paraform results in decreased expression of SQSTM1 protein]
CTD
PMID:37105376
NCBI chr10:34,525,517...34,536,670
Ensembl chr10:34,525,519...34,536,673
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Abcb11
ATP binding cassette subfamily B member 11
affects expression
EXP
Soybean Oil affects the expression of ABCB11 mRNA
CTD
PMID:15770074
NCBI chr 3:54,016,854...54,112,797
Ensembl chr 3:54,017,127...54,112,730
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Abcb1b
ATP-binding cassette, sub-family B member 1B
affects expression
EXP
Soybean Oil affects the expression of ABCB1B mRNA
CTD
PMID:15770074
NCBI chr 4:25,242,761...25,325,194
Ensembl chr 4:25,242,798...25,325,199
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Abcb4
ATP binding cassette subfamily B member 4
affects expression
EXP
Soybean Oil affects the expression of ABCB4 mRNA
CTD
PMID:15770074
NCBI chr 4:25,150,998...25,209,489
Ensembl chr 4:25,151,953...25,209,202
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Abcc1
ATP binding cassette subfamily C member 1
affects expression
EXP
Soybean Oil affects the expression of ABCC1 mRNA
CTD
PMID:15770074
NCBI chr10:528,961...655,179
Ensembl chr10:531,812...655,114
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Abcc2
ATP binding cassette subfamily C member 2
affects expression
EXP
Soybean Oil affects the expression of ABCC2 mRNA
CTD
PMID:15770074
NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238
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Abcc5
ATP binding cassette subfamily C member 5
affects expression
EXP
Soybean Oil affects the expression of ABCC5 mRNA
CTD
PMID:15770074
NCBI chr11:80,473,809...80,567,257
Ensembl chr11:80,473,872...80,567,253
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Abcc6
ATP binding cassette subfamily C member 6
affects expression
EXP
Soybean Oil affects the expression of ABCC6 mRNA
CTD
PMID:15770074
NCBI chr 1:96,447,224...96,501,464
Ensembl chr 1:96,447,251...96,501,464
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Acat1
acetyl-CoA acetyltransferase 1
decreases activity
EXP
Soybean Oil results in decreased activity of ACAT1 protein
CTD
PMID:12559476
NCBI chr 8:53,979,813...54,008,861
Ensembl chr 8:53,979,813...54,008,855
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Bcl2
BCL2, apoptosis regulator
increases expression
EXP
Soybean Oil results in increased expression of BCL2 protein
CTD
PMID:15309441
NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743 Ensembl chr13:22,684,989...22,853,743
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Cat
catalase
increases activity
EXP
Soybean Oil results in increased activity of CAT protein
CTD
PMID:12781854
NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
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Ccnd1
cyclin D1
increases expression
EXP
Soybean Oil results in increased expression of CCND1 mRNA
CTD
PMID:21088903
NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
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Cyp4a1
cytochrome P450, family 4, subfamily a, polypeptide 1
affects expression
EXP
Soybean Oil affects the expression of CYP4A1 mRNA
CTD
PMID:16079505
NCBI chr 5:129,123,323...129,137,464
Ensembl chr 5:129,123,336...129,137,464
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Cyp7a1
cytochrome P450 family 7 subfamily A member 1
increases activity
EXP
Soybean Oil results in increased activity of CYP7A1 protein
CTD
PMID:12559476
NCBI chr 5:19,376,979...19,386,676
Ensembl chr 5:19,376,974...19,386,688
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Gstp1
glutathione S-transferase pi 1
multiple interactions
EXP
Soybean Oil promotes the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of GSTP1 mRNA]; Soybean Oil promotes the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of GSTP1 protein]
CTD
PMID:11600134
NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226
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Hmgcr
3-hydroxy-3-methylglutaryl-CoA reductase
increases activity
EXP
Soybean Oil results in increased activity of HMGCR protein
CTD
PMID:12559476
NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703
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Il12b
interleukin 12B
decreases expression
ISO
Soybean Oil results in decreased expression of IL12B mRNA
CTD
PMID:10065739
NCBI chr10:28,888,832...28,903,802
Ensembl chr10:28,893,008...28,902,903
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Slc22a1
solute carrier family 22 member 1
affects expression
EXP
Soybean Oil affects the expression of SLC22A1 mRNA
CTD
PMID:15770074
NCBI chr 1:48,076,657...48,103,679
Ensembl chr 1:48,076,666...48,103,678
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Slc22a7
solute carrier family 22 member 7
affects expression
EXP
Soybean Oil affects the expression of SLC22A7 mRNA
CTD
PMID:15770074
NCBI chr 9:14,547,073...14,554,354
Ensembl chr 9:14,547,849...14,553,921
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P2rx1
purinergic receptor P2X 1
affects binding
EXP
TNP-ATP binds to P2rx1 protein
RGD
PMID:12237343
RGD:727431
NCBI chr10:57,618,586...57,633,648
Ensembl chr10:57,618,586...57,633,623
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P2rx2
purinergic receptor P2X 2
multiple interactions
EXP
TNP-ATP binds to P2rx2 protein; TNP-ATP inhibits the reaction [ATP binds to P2rx2 protein] in transfected glial cells
RGD
PMID:16388598
RGD:1642662
NCBI chr12:46,338,979...46,342,891
Ensembl chr12:46,339,549...46,342,891
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P2rx5
purinergic receptor P2X 5
affects transport
EXP
TNP-ATP affects transport ion flux of P2rx5 receptor
RGD
PMID:12237343
RGD:727431
NCBI chr10:57,777,737...57,789,426
Ensembl chr10:57,777,819...57,789,423
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