Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:anabolic androgenic steroid
go back to main search page
Accession:CHEBI:50786 term browser browse the term
Definition:A steroid hormone related to the hormone testosterone. It increases protein synthesis within cells, which results in the buildup of cellular tissue (anabolism), especially in muscles. It also has androgenic and virilizing properties.
Synonyms:related_synonym: Anabolic steriod;   anabolic steriods;   anabolic-androgenic steroids
 xref: Wikipedia:Anabolic_steroid



show annotations for term's descendants           Sort by:
17beta-hydroxy-17-methylestra-4,9,11-trien-3-one term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc4 ATP binding cassette subfamily C member 4 increases expression ISO Metribolone results in increased expression of ABCC4 mRNA CTD PMID:17010675 NCBI chr15:95,541,186...95,774,898
Ensembl chr15:95,542,315...95,774,283
JBrowse link
G Acadsb acyl-CoA dehydrogenase, short/branched chain decreases expression ISO Metribolone results in decreased expression of ACADSB protein CTD PMID:17152098 NCBI chr 1:186,188,939...186,227,796
Ensembl chr 1:186,188,987...186,230,379
JBrowse link
G Acp3 acid phosphatase 3 increases expression ISO Metribolone results in increased expression of ACP3 protein CTD PMID:17541959 NCBI chr 8:104,905,570...104,956,146
Ensembl chr 8:104,905,586...104,954,236
JBrowse link
G Acsl3 acyl-CoA synthetase long-chain family member 3 multiple interactions
increases expression
ISO Metribolone promotes the reaction [NDRG1 protein binds to ACSL3 protein]
Metribolone results in increased expression of ACSL3 mRNA
CTD PMID:16751804 PMID:17010675 PMID:17220478 NCBI chr 9:80,115,164...80,164,636
Ensembl chr 9:80,115,112...80,164,627
JBrowse link
G Actb actin, beta multiple interactions
increases expression
ISO Metribolone promotes the reaction [NDRG1 protein binds to ACTB protein]
Metribolone results in increased expression of ACTB protein
CTD PMID:17152098 PMID:17220478 NCBI chr12:11,663,112...11,666,697
Ensembl chr12:11,663,109...11,672,877
JBrowse link
G Actg1 actin, gamma 1 increases expression ISO Metribolone results in increased expression of ACTG1 protein CTD PMID:17152098 NCBI chr10:105,619,738...105,622,587
Ensembl chr10:105,619,737...105,624,232
Ensembl chr 3:105,619,737...105,624,232
JBrowse link
G Adam7 ADAM metallopeptidase domain 7 increases expression ISO Metribolone results in increased expression of ADAM7 mRNA CTD PMID:17010675 NCBI chr15:42,833,796...42,882,201
Ensembl chr15:42,833,796...42,882,201
JBrowse link
G Aida axin interactor, dorsalization associated increases expression ISO Metribolone results in increased expression of AIDA mRNA CTD PMID:17010196 NCBI chr13:94,940,311...94,967,920
Ensembl chr13:94,939,741...94,967,920
JBrowse link
G Aip aryl-hydrocarbon receptor-interacting protein decreases expression ISO Metribolone results in decreased expression of AIP protein CTD PMID:17152098 NCBI chr 1:201,408,002...201,419,220
Ensembl chr 1:201,407,288...201,419,122
JBrowse link
G Akip1 A-kinase interacting protein 1 increases expression ISO Metribolone results in increased expression of AKIP1 mRNA CTD PMID:17010196 NCBI chr 1:163,734,730...163,743,648
Ensembl chr 1:163,734,798...163,743,648
JBrowse link
G Akr1a1 aldo-keto reductase family 1 member A1 increases expression ISO Metribolone results in increased expression of AKR1A1 protein CTD PMID:17152098 NCBI chr 5:130,092,945...130,130,277
Ensembl chr 5:130,092,732...130,113,674
JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions
increases phosphorylation
ISO bicalutamide inhibits the reaction [Metribolone results in increased phosphorylation of AKT1 protein]; Hydrogen Peroxide promotes the reaction [Metribolone results in increased phosphorylation of AKT1 protein] CTD PMID:17325745 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Aldh1a3 aldehyde dehydrogenase 1 family, member A3 increases expression ISO Metribolone results in increased expression of ALDH1A3 mRNA CTD PMID:17526768 NCBI chr 1:119,982,272...120,017,416
Ensembl chr 1:119,982,277...120,017,436
JBrowse link
G Aldh9a1 aldehyde dehydrogenase 9 family, member A1 increases expression ISO Metribolone results in increased expression of ALDH9A1 protein CTD PMID:17152098 NCBI chr13:79,505,738...79,522,539
Ensembl chr13:79,505,695...79,540,568
JBrowse link
G Aldoa aldolase, fructose-bisphosphate A increases expression ISO Metribolone results in increased expression of ALDOA mRNA CTD PMID:17010196 NCBI chr 1:181,402,275...181,407,476
Ensembl chr 1:181,402,275...181,406,182
JBrowse link
G Amh anti-Mullerian hormone multiple interactions ISO AMH protein inhibits the reaction [Metribolone results in increased expression of KLK3 mRNA] CTD PMID:16740653 NCBI chr 7:8,906,776...8,909,192
Ensembl chr 7:8,906,836...8,909,282
JBrowse link
G Anxa4 annexin A4 increases expression ISO Metribolone results in increased expression of ANXA4 protein CTD PMID:17152098 NCBI chr 4:119,184,378...119,241,183
Ensembl chr 4:119,184,374...119,241,161
JBrowse link
G Ap1m2 adaptor related protein complex 1 subunit mu 2 multiple interactions ISO Metribolone promotes the reaction [NDRG1 protein binds to AP1M2 protein] CTD PMID:17220478 NCBI chr 8:19,838,579...19,856,560
Ensembl chr 8:19,838,580...19,856,482
JBrowse link
G Ap2m1 adaptor related protein complex 2 subunit mu 1 multiple interactions ISO Metribolone promotes the reaction [NDRG1 protein binds to AP2M1 protein] CTD PMID:17220478 NCBI chr11:80,355,307...80,364,218
Ensembl chr11:80,328,041...80,364,140
JBrowse link
G Apmap adipocyte plasma membrane associated protein increases expression ISO Metribolone results in increased expression of APMAP protein CTD PMID:17152098 NCBI chr 3:139,409,021...139,437,296
Ensembl chr 3:139,409,022...139,437,341
JBrowse link
G Appbp2 amyloid beta precursor protein binding protein 2 increases expression ISO Metribolone results in increased expression of APPBP2 mRNA CTD PMID:16751804 NCBI chr10:70,057,774...70,099,877
Ensembl chr10:70,057,774...70,099,835
JBrowse link
G Ar androgen receptor decreases expression
affects binding
multiple interactions
affects localization
increases activity
increases expression
ISO
EXP
Metribolone results in decreased expression of AR mRNA; Metribolone results in decreased expression of AR mRNA mutant form
Metribolone binds to AR protein; Metribolone binds to AR protein mutant form
1,2,3,6,7,8-hexachlorodibenzodioxin inhibits the reaction [Metribolone results in increased activity of AR protein]; 1-acetonaphthone inhibits the reaction [Metribolone results in increased activity of AR protein]; 1-aminopyrene inhibits the reaction [Metribolone results in increased activity of AR protein]; 1-hydroxypyrene inhibits the reaction [Metribolone results in increased activity of AR protein]; 1-nitropyrene inhibits the reaction [Metribolone results in increased activity of AR protein]; 16 alpha,17-epoxyprogesterone inhibits the reaction [Metribolone results in increased activity of AR protein]; 17 alpha,20 beta-dihydroxypregn-4-en-3-one inhibits the reaction [Metribolone results in increased activity of AR protein]; 17-(5'-isoxazolyl)androsta-4,16-dien-3-one inhibits the reaction [Metribolone binds to AR protein]; 2,2',3',4,4',5-hexachlorobiphenyl inhibits the reaction [Metribolone results in increased activity of AR protein]; 2,2',4,5'-tetrabromodiphenyl ether inhibits the reaction [Metribolone results in increased activity of AR protein]; 2,2',4,5'-tetrachlorobiphenyl inhibits the reaction [Metribolone results in increased activity of AR protein]; 2,2'-biphenol inhibits the reaction [Metribolone results in increased activity of AR protein]; 2,2'-dichlorobiphenyl inhibits the reaction [Metribolone results in increased activity of AR protein]; 2,2-(2-chlorophenyl-4'-chlorophenyl)-1,1-dichloroethene inhibits the reaction [Metribolone results in increased activity of AR protein]; 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane inhibits the reaction [Metribolone binds to and results in increased activity of AR protein]; 2,2-di(4-methacryloxyphenyl)propane inhibits the reaction [Metribolone results in increased activity of AR protein]; 2,3',4,4',5-pentachlorobiphenyl inhibits the reaction [Metribolone results in increased activity of AR protein]; 2,3',4,4'-tetrachlorobiphenyl inhibits the reaction [Metribolone results in increased activity of AR protein]; 2,3,3',4,4',5-hexachlorobiphenyl inhibits the reaction [Metribolone results in increased activity of AR protein]; 2,3,3',4,4'-pentachlorobiphenyl inhibits the reaction [Metribolone results in increased activity of AR protein]; 2,3,4',6-tetrachlorobiphenyl inhibits the reaction [Metribolone results in increased activity of AR protein]; 2,3,4,4'5-pentachlorobiphenyl inhibits the reaction [Metribolone results in increased activity of AR protein]; 2,3,4,5,6-pentachloroaniline inhibits the reaction [Metribolone results in increased activity of AR protein]; 2,3,4,7,8-pentachlorodibenzofuran inhibits the reaction [Metribolone results in increased activity of AR protein]; 2,3,5,6-tetrachlorobiphenyl inhibits the reaction [Metribolone results in increased activity of AR protein]; 2,3,5,6-tetrachlorohydroquinone inhibits the reaction [Metribolone results in increased activity of AR protein]; 2,3-dichlorobiphenyl inhibits the reaction [Metribolone results in increased activity of AR protein]; 2,4'-dichlorobiphenyl inhibits the reaction [Metribolone results in increased activity of AR protein]; 2,4,4',5-tetrachlorobiphenyl inhibits the reaction [Metribolone results in increased activity of AR protein]; 2,4,4'-trichlorobiphenyl inhibits the reaction [Metribolone results in increased activity of AR protein]; 2,4,6-trichlorobiphenyl inhibits the reaction [Metribolone results in increased activity of AR protein]; 2,5,3'-trichlorobiphenyl inhibits the reaction [Metribolone results in increased activity of AR protein]; 2,6-di-tert-butyl-4-hydroxymethylphenol inhibits the reaction [Metribolone results in increased activity of AR protein]; 2,6-dichlorobiphenyl inhibits the reaction [Metribolone results in increased activity of AR protein]; 2-aminodiphenyl inhibits the reaction [Metribolone results in increased activity of AR protein]; 2-anthramine inhibits the reaction [Metribolone results in increased activity of AR protein]; 2-chlorobiphenyl inhibits the reaction [Metribolone results in increased activity of AR protein]; 2-tert-butylhydroquinone inhibits the reaction [Metribolone results in increased activity of AR protein]; 20-hydroximino-4,16-pregnadien-3-one inhibits the reaction [Metribolone binds to AR protein]; 3,3'-Dichlorobenzidine inhibits the reaction [Metribolone results in increased activity of AR protein]; 3,3'-dichlorobiphenyl inhibits the reaction [Metribolone results in increased activity of AR protein]; 3,4,5,3',4'-pentachlorobiphenyl inhibits the reaction [Metribolone results in increased activity of AR protein]; 3,5-dichlorobiphenyl inhibits the reaction [Metribolone results in increased activity of AR protein]; 4,16-androstadien-3-one analog inhibits the reaction [Metribolone binds to AR protein]; 4-benzylpyridine inhibits the reaction [Metribolone results in increased activity of AR protein]; 4-methylbenzenethiol inhibits the reaction [Metribolone results in increased activity of AR protein]; 4-phenylphenol inhibits the reaction [Metribolone binds to AR protein]; 4-tert-octylphenol inhibits the reaction [Metribolone results in increased activity of AR protein]; 6-(3-(4-cyano-3-trifluoromethylphenyl)-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl)pyridine-2-sulfonic acid amide inhibits the reaction [Metribolone affects the localization of AR protein]; 9,10-Dimethyl-1,2-benzanthracene inhibits the reaction [Metribolone results in increased activity of AR protein]; 9,10-dimethylanthracene inhibits the reaction [Metribolone results in increased activity of AR protein]; 9-methylanthracene inhibits the reaction [Metribolone results in increased activity of AR protein]; [4,4'-hexafluorisopropylidene diphenol binds to and results in decreased activity of AR protein] inhibits the reaction [Metribolone binds to AR protein]; [4,4'-hexafluorisopropylidene diphenol binds to and results in decreased activity of AR protein] which results in decreased susceptibility to Metribolone; [bisphenol A binds to and results in decreased activity of AR protein] inhibits the reaction [Metribolone binds to AR protein]; [bisphenol A binds to and results in decreased activity of AR protein] which results in decreased susceptibility to Metribolone; [iprodione binds to and results in decreased activity of AR protein] inhibits the reaction [Metribolone binds to AR protein]; [Metribolone binds to and affects the folding of AR protein] affects the reaction [AR protein modified form binds to CNOT1 protein modified form]; [Metribolone binds to and affects the folding of AR protein] affects the reaction [AR protein modified form binds to EP300 protein modified form]; [Metribolone binds to and affects the folding of AR protein] affects the reaction [AR protein modified form binds to HELZ2 protein modified form]; [Metribolone binds to and affects the folding of AR protein] affects the reaction [AR protein modified form binds to NCOA3 protein modified form]; [Metribolone binds to and affects the folding of AR protein] affects the reaction [AR protein modified form binds to NCOR1 protein modified form]; [Metribolone binds to and affects the folding of AR protein] affects the reaction [AR protein modified form binds to NR0B2 protein modified form]; [Metribolone binds to and affects the folding of AR protein] affects the reaction [AR protein modified form binds to TRERF1 protein modified form]; [Metribolone binds to and affects the folding of AR protein] inhibits the reaction [AR protein modified form binds to CHD9 protein modified form]; [Metribolone binds to and affects the folding of AR protein] inhibits the reaction [AR protein modified form binds to DHX30 protein modified form]; [Metribolone binds to and affects the folding of AR protein] inhibits the reaction [AR protein modified form binds to GNAQ protein modified form]; [Metribolone binds to and affects the folding of AR protein] inhibits the reaction [AR protein modified form binds to HR protein modified form]; [Metribolone binds to and affects the folding of AR protein] inhibits the reaction [AR protein modified form binds to ITGB3BP protein modified form]; [Metribolone binds to and affects the folding of AR protein] inhibits the reaction [AR protein modified form binds to KAT2B protein modified form]; [Metribolone binds to and affects the folding of AR protein] inhibits the reaction [AR protein modified form binds to MEN1 protein modified form]; [Metribolone binds to and affects the folding of AR protein] inhibits the reaction [AR protein modified form binds to MGMT protein modified form]; [Metribolone binds to and affects the folding of AR protein] inhibits the reaction [AR protein modified form binds to NCOR2 protein modified form]; [Metribolone binds to and affects the folding of AR protein] inhibits the reaction [AR protein modified form binds to NELFB protein modified form]; [Metribolone binds to and affects the folding of AR protein] inhibits the reaction [AR protein modified form binds to NFKBIB protein modified form]; [Metribolone binds to and affects the folding of AR protein] inhibits the reaction [AR protein modified form binds to NRIP1 protein modified form]; [Metribolone binds to and affects the folding of AR protein] inhibits the reaction [AR protein modified form binds to PELP1 protein modified form]; [Metribolone binds to and affects the folding of AR protein] inhibits the reaction [AR protein modified form binds to PIAS2 protein modified form]; [Metribolone binds to and affects the folding of AR protein] inhibits the reaction [AR protein modified form binds to PPRC1 protein modified form]; [Metribolone binds to and affects the folding of AR protein] inhibits the reaction [AR protein modified form binds to PRAME protein modified form]; [Metribolone binds to and affects the folding of AR protein] inhibits the reaction [AR protein modified form binds to TGFB1I1 protein modified form]; [Metribolone binds to and affects the folding of AR protein] inhibits the reaction [AR protein modified form binds to TRIM24 protein modified form]; [Metribolone binds to and affects the folding of AR protein] inhibits the reaction [AR protein modified form binds to TRRAP protein modified form]; [Metribolone binds to and affects the folding of AR protein] inhibits the reaction [AR protein modified form binds to ZNHIT3 protein modified form]; [Metribolone binds to and affects the folding of AR protein] promotes the reaction [AR protein modified form binds to AR protein modified form]; [Metribolone binds to and affects the folding of AR protein] promotes the reaction [AR protein modified form binds to BRD8 protein modified form]; [Metribolone binds to and affects the folding of AR protein] promotes the reaction [AR protein modified form binds to CREBBP protein modified form]; [Metribolone binds to and affects the folding of AR protein] promotes the reaction [AR protein modified form binds to GSN protein modified form]; [Metribolone binds to and affects the folding of AR protein] promotes the reaction [AR protein modified form binds to JMJD1C protein modified form]; [Metribolone binds to and affects the folding of AR protein] promotes the reaction [AR protein modified form binds to LCOR protein modified form]; [Metribolone binds to and affects the folding of AR protein] promotes the reaction [AR protein modified form binds to MED1 protein modified form]; [Metribolone binds to and affects the folding of AR protein] promotes the reaction [AR protein modified form binds to NCOA1 protein modified form]; [Metribolone binds to and affects the folding of AR protein] promotes the reaction [AR protein modified form binds to NCOA2 protein modified form]; [Metribolone binds to and affects the folding of AR protein] promotes the reaction [AR protein modified form binds to NCOA6 protein modified form]; [Metribolone binds to and affects the folding of AR protein] promotes the reaction [AR protein modified form binds to NR0B1 protein modified form]; [Metribolone binds to and affects the folding of AR protein] promotes the reaction [AR protein modified form binds to PPARGC1A protein modified form]; [Metribolone binds to and affects the folding of AR protein] promotes the reaction [AR protein modified form binds to PRDM2 protein modified form]; [Metribolone binds to and affects the folding of AR protein] promotes the reaction [AR protein modified form binds to RBL2 protein modified form]; [Metribolone binds to and affects the folding of AR protein] promotes the reaction [AR protein modified form binds to RELA protein modified form]; [Metribolone binds to and affects the folding of AR protein] promotes the reaction [AR protein modified form binds to SLC30A9 protein modified form]; [Metribolone binds to and results in increased activity of AR protein] which results in increased expression of KLK3 protein; [vinclozolin binds to and results in decreased activity of AR protein] inhibits the reaction [Metribolone binds to AR protein]; Acriflavine inhibits the reaction [Metribolone results in increased activity of AR protein]; alachlor inhibits the reaction [Metribolone results in increased activity of AR protein]; alpha,alpha-dimethoxytoluene inhibits the reaction [Metribolone results in increased activity of AR protein]; alpha-hexachlorocyclohexane inhibits the reaction [Metribolone results in increased activity of AR protein]; androsta-5,16-dien-3 beta-ol analog inhibits the reaction [Metribolone binds to AR protein]; anthracene inhibits the reaction [Metribolone results in increased activity of AR protein]; AR mRNA affects the reaction [Metribolone results in increased expression of ARG1 protein]; AR mRNA affects the reaction [Metribolone results in increased expression of ARG2 protein]; AR mRNA affects the reaction [Metribolone results in increased secretion of CXCL8 protein]; AR protein affects the reaction [Metribolone results in decreased expression of MIR204 mRNA]; AR protein affects the reaction [Metribolone results in decreased expression of SESN1 protein]; AR protein affects the reaction [Metribolone results in increased abundance of Reactive Oxygen Species]; AR protein promotes the reaction [Metribolone results in increased expression of ATP7B mRNA]; AR protein promotes the reaction [Metribolone results in increased expression of SLC31A1 mRNA]; AR protein promotes the reaction [Metribolone results in increased expression of SLC31A1 protein]; AR protein promotes the reaction [Metribolone results in increased expression of STEAP4 mRNA]; Arsenic Trioxide inhibits the reaction [Metribolone promotes the reaction [AR protein binds to KLK3 promoter]]; Benzhydryl Compounds inhibits the reaction [Metribolone results in increased activity of AR protein]; Benzo(a)pyrene inhibits the reaction [Metribolone binds to and results in increased activity of AR protein]; Benzo(a)pyrene inhibits the reaction [Metribolone results in increased activity of AR protein]; Benzo(a)pyrene metabolite inhibits the reaction [Metribolone binds to and results in increased activity of AR protein]; benzo(j)fluoranthene inhibits the reaction [Metribolone results in increased activity of AR protein]; benzo(k)fluoranthene inhibits the reaction [Metribolone results in increased activity of AR protein]; Benzophenones inhibits the reaction [Metribolone results in increased activity of AR protein]; bicalutamide inhibits the reaction [[Metribolone binds to and results in increased activity of AR protein] which results in increased expression of KLK3 protein]; bicalutamide inhibits the reaction [Metribolone results in increased activity of AR protein mutant form]; bicalutamide inhibits the reaction [Metribolone results in increased activity of AR protein]; bicalutamide inhibits the reaction [Metribolone results in increased folding of and results in increased stability of AR protein]; bifenox inhibits the reaction [Metribolone results in increased activity of AR protein]; bisphenol A inhibits the reaction [Metribolone results in increased activity of AR protein]; bitertanol inhibits the reaction [Metribolone binds to and results in increased activity of AR protein]; Bortezomib inhibits the reaction [Metribolone results in increased activity of AR protein]; Budesonide inhibits the reaction [Metribolone results in increased activity of AR protein]; Busulfan inhibits the reaction [Metribolone results in increased activity of AR protein]; Cadmium Chloride inhibits the reaction [Metribolone binds to AR protein]; carfilzomib inhibits the reaction [Metribolone results in increased activity of AR protein]; CH 5166623 inhibits the reaction [Metribolone affects the localization of AR protein]; CH4933468 inhibits the reaction [Metribolone affects the localization of AR protein]; chlorobenzilate inhibits the reaction [Metribolone results in increased activity of AR protein]; chlorocresol inhibits the reaction [Metribolone results in increased activity of AR protein]; chrysene inhibits the reaction [Metribolone results in increased activity of AR protein]; Colforsin promotes the reaction [Metribolone results in increased activity of AR protein]; corticosterone acetate inhibits the reaction [Metribolone results in increased activity of AR protein]; Corticosterone inhibits the reaction [Metribolone results in increased activity of AR protein]; Cosmetics inhibits the reaction [Metribolone results in increased activity of AR protein]; Cyclohexylamines inhibits the reaction [Metribolone results in increased activity of AR protein]; Cyclopentanes inhibits the reaction [Metribolone results in increased activity of AR protein]; cypermethrin inhibits the reaction [Metribolone results in increased activity of AR protein]; Cyproterone Acetate inhibits the reaction [[Metribolone binds to and results in increased activity of AR protein] which results in increased expression of KLK3 protein]; Cyproterone Acetate inhibits the reaction [Metribolone results in increased activity of AR protein]; Cyproterone Acetate promotes the reaction [Metribolone results in increased expression of AR mRNA]; DDT inhibits the reaction [Metribolone affects the localization of AR protein]; DDT inhibits the reaction [Metribolone promotes the reaction [AR protein binds to KLK3 promoter]]; DDT inhibits the reaction [Metribolone results in increased expression of AR protein]; Deanol inhibits the reaction [Metribolone results in increased activity of AR protein]; Dexamethasone inhibits the reaction [Metribolone results in increased activity of AR protein]; diallyl trisulfide inhibits the reaction [Metribolone affects the localization of AR protein]; Dianisidine inhibits the reaction [Metribolone results in increased activity of AR protein]; dichlone inhibits the reaction [Metribolone results in increased activity of AR protein]; Dichlorodiphenyl Dichloroethylene analog inhibits the reaction [Metribolone results in increased activity of AR protein]; Dichlorodiphenyl Dichloroethylene inhibits the reaction [Metribolone affects the localization of AR protein]; Dichlorodiphenyl Dichloroethylene inhibits the reaction [Metribolone binds to and results in increased activity of AR protein]; Dichlorodiphenyl Dichloroethylene inhibits the reaction [Metribolone promotes the reaction [AR protein binds to KLK3 promoter]]; Dichlorodiphenyl Dichloroethylene inhibits the reaction [Metribolone results in increased activity of AR protein]; Dichlorodiphenyl Dichloroethylene inhibits the reaction [Metribolone results in increased expression of AR protein]; Dichlorvos promotes the reaction [Metribolone results in increased activity of AR protein]; dichlozolinate inhibits the reaction [Metribolone results in increased activity of AR protein]; Dicofol inhibits the reaction [Metribolone results in increased activity of AR protein]; Dieldrin inhibits the reaction [Metribolone results in increased activity of AR protein]; Diethylstilbestrol inhibits the reaction [Metribolone results in increased activity of AR protein]; Diuron inhibits the reaction [Metribolone results in increased activity of AR protein]; Endosulfan inhibits the reaction [Metribolone results in increased activity of AR protein]; enilconazole inhibits the reaction [Metribolone results in increased activity of AR protein]; enzacamene inhibits the reaction [Metribolone binds to and results in increased activity of AR protein]; epoxiconazole inhibits the reaction [Metribolone results in increased activity of AR protein]; Estradiol inhibits the reaction [Metribolone results in increased activity of AR protein]; Estriol inhibits the reaction [Metribolone results in increased activity of AR protein]; Ethinyl Estradiol inhibits the reaction [Metribolone results in increased activity of AR protein]; Etoposide inhibits the reaction [Metribolone results in increased activity of AR protein]; fenarimol inhibits the reaction [Metribolone results in increased activity of AR protein]; Fenitrothion inhibits the reaction [Metribolone results in increased activity of AR protein]; Fenthion inhibits the reaction [Metribolone results in increased activity of AR protein]; Finasteride inhibits the reaction [Metribolone results in increased activity of AR protein]; fisetin inhibits the reaction [Metribolone results in increased folding of and results in increased stability of AR protein]; Flame Retardants inhibits the reaction [Metribolone results in increased activity of AR protein]; fluoranthene inhibits the reaction [Metribolone results in increased activity of AR protein]; fluoxastrobin inhibits the reaction [Metribolone results in increased activity of AR protein]; Flutamide inhibits the reaction [Metribolone binds to and results in increased activity of AR protein]; Flutamide inhibits the reaction [Metribolone binds to AR protein]; Food Additives inhibits the reaction [Metribolone results in increased activity of AR protein]; galaxolide inhibits the reaction [Metribolone results in increased activity of AR protein]; gamma-Linolenic Acid inhibits the reaction [Metribolone results in increased activity of AR protein]; Hexylresorcinol inhibits the reaction [Metribolone results in increased activity of AR protein]; homosalate inhibits the reaction [Metribolone binds to and results in increased activity of AR protein]; homosalate inhibits the reaction [Metribolone results in increased activity of AR protein]; Hydrocarbons, Chlorinated inhibits the reaction [Metribolone results in increased activity of AR protein]; hydroxyflutamide inhibits the reaction [Metribolone results in increased activity of AR protein]; IL6 protein inhibits the reaction [Metribolone results in increased activity of AR protein]; Ketoconazole inhibits the reaction [Metribolone results in increased activity of AR protein]; Linuron inhibits the reaction [Metribolone binds to AR protein]; Linuron inhibits the reaction [Metribolone results in increased activity of AR protein]; mancozeb inhibits the reaction [Metribolone binds to and results in increased activity of AR protein]; meprednisone inhibits the reaction [Metribolone results in increased activity of AR protein]; Methiocarb inhibits the reaction [Metribolone results in increased activity of AR protein]; methoxyacetic acid promotes the reaction [Metribolone results in increased activity of AR protein]; Methoxychlor inhibits the reaction [Metribolone binds to and results in increased activity of AR protein]; Methoxychlor inhibits the reaction [Metribolone results in increased activity of AR protein]; Methoxychlor metabolite inhibits the reaction [Metribolone binds to and results in increased activity of AR protein]; Methyl Parathion inhibits the reaction [Metribolone results in increased activity of AR protein]; metoprine inhibits the reaction [Metribolone results in increased activity of AR protein]; Metribolone binds to and affects the folding of AR protein; Metribolone binds to and results in increased activity of AR protein; Metribolone inhibits the reaction [CREBBP protein results in increased activity of AR protein]; Metribolone inhibits the reaction [NCOA1 protein results in increased activity of AR protein]; Metribolone inhibits the reaction [NCOA3 protein results in increased activity of AR protein]; Metribolone promotes the reaction [AR protein binds to ATR promoter]; Metribolone promotes the reaction [AR protein binds to CLU enhancer]; Metribolone promotes the reaction [AR protein binds to GSTE1 promoter]; Metribolone promotes the reaction [AR protein binds to IGFBP3 promoter]; Metribolone promotes the reaction [AR protein binds to KLK3 enhancer]; Metribolone promotes the reaction [AR protein binds to KLK3 promoter]; Metribolone promotes the reaction [AR protein binds to NKX3-1 enhancer]; Metribolone promotes the reaction [AR protein binds to NKX3-1 promoter]; Metribolone results in increased folding of and results in increased stability of AR protein; Metribolone results in increased localization of and results in increased activity of AR protein; Mifepristone inhibits the reaction [Metribolone binds to and results in increased activity of AR protein]; Mifepristone inhibits the reaction [Metribolone results in increased activity of AR protein mutant form]; Mifepristone inhibits the reaction [Metribolone results in increased activity of AR protein]; nilutamide inhibits the reaction [Metribolone results in increased activity of AR protein]; Nitrobenzenes inhibits the reaction [Metribolone results in increased activity of AR protein]; nitrofen inhibits the reaction [Metribolone results in increased activity of AR protein]; nonylphenol inhibits the reaction [Metribolone results in increased activity of AR protein]; nootkatone inhibits the reaction [Metribolone results in increased activity of AR protein]; o,p'-DDT inhibits the reaction [Metribolone results in increased activity of AR protein]; PA2G4 protein inhibits the reaction [Cyproterone Acetate promotes the reaction [Metribolone results in increased expression of AR mRNA]]; PA2G4 protein inhibits the reaction [Metribolone results in increased expression of AR mRNA]; pentabrominated diphenyl ether 100 inhibits the reaction [Metribolone results in increased activity of AR protein]; Pesticides inhibits the reaction [Metribolone results in increased activity of AR protein]; Plasticizers inhibits the reaction [Metribolone results in increased activity of AR protein]; Pregnadienes analog inhibits the reaction [Metribolone binds to AR protein]; prochloraz inhibits the reaction [Metribolone results in increased activity of AR protein]; procymidone inhibits the reaction [Metribolone binds to and results in increased activity of AR protein]; procymidone inhibits the reaction [Metribolone binds to AR protein]; procymidone inhibits the reaction [Metribolone results in increased activity of AR protein]; Proflavine inhibits the reaction [Metribolone results in increased activity of AR protein]; Progesterone inhibits the reaction [Metribolone results in increased activity of AR protein]; propiconazole inhibits the reaction [Metribolone binds to and results in increased activity of AR protein]; propiconazole inhibits the reaction [Metribolone results in increased activity of AR protein]; pyrene inhibits the reaction [Metribolone results in increased activity of AR protein]; pyridaben inhibits the reaction [Metribolone results in increased activity of AR protein]; retene inhibits the reaction [Metribolone results in increased activity of AR protein]; ronnel inhibits the reaction [Metribolone results in increased activity of AR protein]; Spironolactone inhibits the reaction [Metribolone binds to and results in increased activity of AR protein]; Spironolactone inhibits the reaction [Metribolone results in increased activity of AR protein]; ST 1481 inhibits the reaction [Metribolone results in increased activity of AR protein]; tebuconazole inhibits the reaction [Metribolone results in increased activity of AR protein]; tetrabromobisphenol A inhibits the reaction [Metribolone results in increased activity of AR protein]; Topotecan inhibits the reaction [Metribolone results in increased activity of AR protein]; Toxaphene inhibits the reaction [Metribolone results in increased activity of AR protein]; Trenbolone Acetate inhibits the reaction [Metribolone results in increased activity of AR protein]; triadimefon inhibits the reaction [Metribolone results in increased activity of AR protein]; Triclosan inhibits the reaction [Metribolone results in increased activity of AR protein]; trifloxystrobin inhibits the reaction [Metribolone results in increased activity of AR protein]; tris(1,3-dichloro-2-propyl)phosphate affects the reaction [Metribolone affects the localization of AR protein]; tris(1,3-dichloro-2-propyl)phosphate inhibits the reaction [Metribolone results in increased expression of AR protein]; trityl chloride inhibits the reaction [Metribolone results in increased activity of AR protein]; Vehicle Emissions analog inhibits the reaction [Metribolone binds to AR protein]; vinclozolin inhibits the reaction [Metribolone results in increased activity of AR protein]; vinclozolin metabolite inhibits the reaction [Metribolone results in increased activity of AR protein]; Zearalenone inhibits the reaction [Metribolone results in increased activity of AR protein]
Metribolone results in increased activity of AR protein; Metribolone results in increased activity of AR protein mutant form
Metribolone results in increased expression of AR mRNA; Metribolone results in increased expression of AR protein
1-methylphenanthrene inhibits the reaction [Metribolone binds to AR protein]; 1-naphthaldehyde inhibits the reaction [Metribolone binds to AR protein]; 1-naphthol inhibits the reaction [Metribolone binds to AR protein]; 10,11-dihydro-5H-dibenzo(a,d)cycloheptene analog inhibits the reaction [Metribolone binds to AR protein]; 10,11-dihydro-5H-dibenzo(a,d)cycloheptene inhibits the reaction [Metribolone binds to AR protein]; 2,2',4,4',5-brominated diphenyl ether inhibits the reaction [Metribolone binds to AR protein]; 2,2',4,4'-tetrabromodiphenyl ether inhibits the reaction [Metribolone binds to AR protein]; 2-methylphenanthrene inhibits the reaction [Metribolone binds to AR protein]; 2-naphthol inhibits the reaction [Metribolone binds to AR protein]; 9-phenanthrol inhibits the reaction [Metribolone binds to AR protein]; Anthracenes analog inhibits the reaction [Metribolone binds to AR protein]; benzaldehyde inhibits the reaction [Metribolone binds to AR protein]; Biphenyl Compounds analog inhibits the reaction [Metribolone binds to AR protein]; decamethrin inhibits the reaction [Metribolone results in increased expression of AR mRNA]; Dihydrotestosterone inhibits the reaction [Metribolone binds to AR protein]; Flame Retardants inhibits the reaction [Metribolone binds to AR protein]; hexabromodiphenyl ether 154 inhibits the reaction [Metribolone binds to AR protein]; hydroxyflutamide inhibits the reaction [Metribolone binds to AR protein]; Linuron inhibits the reaction [Metribolone binds to AR protein]; Methiocarb inhibits the reaction [Metribolone results in increased expression of AR mRNA]; naphthalene inhibits the reaction [Metribolone binds to AR protein]; Naphthols analog inhibits the reaction [Metribolone binds to AR protein]; pentabrominated diphenyl ether 100 inhibits the reaction [Metribolone binds to AR protein]; pentabromodiphenyl ether inhibits the reaction [Metribolone binds to AR protein]; phenanthrene analog inhibits the reaction [Metribolone binds to AR protein]; phenanthrene inhibits the reaction [Metribolone binds to AR protein]; Phenols analog inhibits the reaction [Metribolone binds to AR protein]; prochloraz inhibits the reaction [Metribolone binds to AR protein]; prochloraz inhibits the reaction [Metribolone results in increased expression of AR mRNA]; Tetrahydronaphthalenes inhibits the reaction [Metribolone binds to AR protein]
AR protein promotes the reaction [Metribolone results in increased expression of FSHB mRNA]
CTD PMID:3695475 PMID:10053169 PMID:10188193 PMID:10771140 PMID:10910998 More... NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925
JBrowse link
G Arcn1 archain 1 increases expression ISO Metribolone results in increased expression of ARCN1 protein CTD PMID:17152098 NCBI chr 8:45,057,617...45,082,224
Ensembl chr 8:45,057,619...45,082,247
JBrowse link
G Arg1 arginase 1 multiple interactions
increases expression
ISO AR mRNA affects the reaction [Metribolone results in increased expression of ARG1 protein]; CXCL8 mRNA affects the reaction [Metribolone results in increased expression of ARG1 protein] CTD PMID:20711410 NCBI chr 1:20,475,878...20,488,422
Ensembl chr 1:20,475,968...20,488,422
JBrowse link
G Arg2 arginase 2 multiple interactions
increases expression
ISO AR mRNA affects the reaction [Metribolone results in increased expression of ARG2 protein]; CXCL8 mRNA affects the reaction [Metribolone results in increased expression of ARG2 protein]
Metribolone results in increased expression of ARG2 mRNA; Metribolone results in increased expression of ARG2 protein
CTD PMID:20711410 NCBI chr 6:97,936,002...97,961,379
Ensembl chr 6:97,936,002...97,961,378
JBrowse link
G Arhgap1 Rho GTPase activating protein 1 increases expression ISO Metribolone results in increased expression of ARHGAP1 protein CTD PMID:17152098 NCBI chr 3:77,621,377...77,643,400
Ensembl chr 3:77,620,655...77,643,396
JBrowse link
G Asns asparagine synthetase (glutamine-hydrolyzing) decreases expression ISO Metribolone results in decreased expression of ASNS protein CTD PMID:17152098 NCBI chr 4:35,784,995...35,803,474
Ensembl chr 4:35,785,237...35,803,423
JBrowse link
G Atf3 activating transcription factor 3 increases expression ISO Metribolone results in increased expression of ATF3 protein CTD PMID:16516039 NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631
JBrowse link
G Atm ATM serine/threonine kinase multiple interactions
increases phosphorylation
ISO [ATM mutant form inhibits the reaction [Metribolone results in increased expression of H2AX protein]] which results in increased expression of ERG mRNA; ATM mutant form inhibits the reaction [Metribolone results in increased expression of H2AX protein]
Metribolone results in increased phosphorylation of ATM protein
CTD PMID:23272087 NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437
JBrowse link
G Atp1a1 ATPase Na+/K+ transporting subunit alpha 1 multiple interactions ISO Metribolone promotes the reaction [NDRG1 protein binds to ATP1A1 protein] CTD PMID:17220478 NCBI chr 2:189,020,722...189,048,826
Ensembl chr 2:189,020,722...189,048,837
JBrowse link
G Atp7b ATPase copper transporting beta multiple interactions
increases expression
ISO AR protein promotes the reaction [Metribolone results in increased expression of ATP7B mRNA] CTD PMID:25320179 NCBI chr16:69,952,286...70,024,404
Ensembl chr16:69,951,778...70,023,636
JBrowse link
G Atr ATR serine/threonine kinase multiple interactions
increases phosphorylation
increases expression
ISO ATR mutant form inhibits the reaction [Metribolone results in increased expression of H2AX protein]; Metribolone promotes the reaction [AR protein binds to ATR promoter]; Metribolone promotes the reaction [UXT protein binds to ATR promoter]
Metribolone results in increased phosphorylation of ATR protein
Metribolone results in increased expression of ATR mRNA
CTD PMID:19318562 PMID:23272087 NCBI chr 8:96,426,704...96,524,152
Ensembl chr 8:96,426,724...96,524,136
JBrowse link
G Atxn3 ataxin 3 increases expression ISO Metribolone results in increased expression of ATXN3 mRNA CTD PMID:16751804 NCBI chr 6:121,072,228...121,107,902
Ensembl chr 6:121,074,448...121,107,902
JBrowse link
G B2m beta-2 microglobulin increases expression
multiple interactions
ISO Metribolone results in increased expression of B2M mRNA
Metribolone results in increased expression of and results in increased secretion of B2M protein; resveratrol inhibits the reaction [Metribolone results in increased expression of B2M mRNA]
CTD PMID:17131305 PMID:17404077 PMID:18586690 NCBI chr 3:109,095,740...109,101,764
Ensembl chr 3:109,095,729...109,101,766
JBrowse link
G Bcas1 brain enriched myelin associated protein 1 increases expression ISO Metribolone results in increased expression of BCAS1 mRNA CTD PMID:17010196 NCBI chr 3:159,136,077...159,219,072
Ensembl chr 3:159,136,083...159,219,106
JBrowse link
G Bglap bone gamma-carboxyglutamate protein increases expression ISO Metribolone results in increased expression of BGLAP mRNA CTD PMID:19759027 NCBI chr 2:173,838,518...173,839,495
Ensembl chr 2:173,838,518...173,839,495
JBrowse link
G Blcap BLCAP, apoptosis inducing factor increases expression ISO Metribolone results in increased expression of BLCAP mRNA CTD PMID:17010196 NCBI chr 3:146,222,699...146,232,859
Ensembl chr 3:146,222,240...146,232,909
JBrowse link
G Blvra biliverdin reductase A increases expression ISO Metribolone results in increased expression of BLVRA protein CTD PMID:17152098 NCBI chr 3:114,340,778...114,366,048
Ensembl chr 3:114,340,838...114,366,033
JBrowse link
G Brca1 BRCA1, DNA repair associated increases expression ISO Metribolone results in increased expression of BRCA1 mRNA CTD PMID:17010196 NCBI chr10:86,417,441...86,477,762
Ensembl chr10:86,418,000...86,477,304
JBrowse link
G Brca2 BRCA2, DNA repair associated increases expression ISO Metribolone results in increased expression of BRCA2 mRNA CTD PMID:17010196 NCBI chr12:59,492...103,789
Ensembl chr12:59,819...100,567
JBrowse link
G Brd8 bromodomain containing 8 multiple interactions ISO [Metribolone binds to and affects the folding of AR protein] promotes the reaction [AR protein modified form binds to BRD8 protein modified form] CTD PMID:28751236 NCBI chr18:26,204,892...26,229,999
Ensembl chr18:26,181,732...26,229,884
JBrowse link
G Bri3 brain protein I3 affects splicing ISO Metribolone affects the splicing of BRI3 mRNA CTD PMID:17010196 NCBI chr12:10,341,007...10,364,655
Ensembl chr12:10,341,011...10,364,735
JBrowse link
G Brip1 BRCA1 interacting DNA helicase 1 increases expression
multiple interactions
ISO Metribolone results in increased expression of BRIP1 mRNA
UXT protein affects the reaction [Metribolone results in increased expression of BRIP1 mRNA]
CTD PMID:19318562 NCBI chr10:70,907,266...71,031,502
Ensembl chr10:70,907,371...71,030,324
JBrowse link
G Brms1 BRMS1, transcriptional repressor and anoikis regulator increases expression ISO Metribolone results in increased expression of BRMS1 mRNA CTD PMID:17010196 NCBI chr 1:202,345,766...202,355,028
Ensembl chr 1:202,345,704...202,355,028
JBrowse link
G Bub1 BUB1 mitotic checkpoint serine/threonine kinase increases expression ISO Metribolone results in increased expression of BUB1 mRNA CTD PMID:19318562 NCBI chr 3:115,020,254...115,051,650
Ensembl chr 3:115,020,254...115,051,650
JBrowse link
G C13h1orf116 similar to human chromosome 1 open reading frame 116 increases expression ISO Metribolone results in increased expression of C1ORF116 mRNA CTD PMID:17010675 NCBI chr13:42,187,442...42,201,432
Ensembl chr13:42,188,609...42,201,426
JBrowse link
G Camkk2 calcium/calmodulin-dependent protein kinase kinase 2 increases expression ISO Metribolone results in increased expression of CAMKK2 mRNA CTD PMID:16751804 NCBI chr12:33,791,023...33,845,000
Ensembl chr12:33,791,052...33,843,279
JBrowse link
G Canx calnexin multiple interactions ISO Metribolone promotes the reaction [NDRG1 protein binds to CANX protein] CTD PMID:17220478 NCBI chr10:34,623,865...34,656,866
Ensembl chr10:34,625,191...34,656,821
JBrowse link
G Capza1 capping actin protein of muscle Z-line subunit alpha 1 increases expression ISO Metribolone results in increased expression of CAPZA1 protein CTD PMID:17152098 NCBI chr 2:192,319,696...192,364,755
Ensembl chr 2:192,319,702...192,364,480
JBrowse link
G Capzb capping actin protein of muscle Z-line subunit beta increases expression ISO Metribolone results in increased expression of CAPZB protein CTD PMID:17152098 NCBI chr 5:151,435,600...151,535,409
Ensembl chr 5:151,434,871...151,535,409
JBrowse link
G Casc3 CASC3 exon junction complex subunit increases expression ISO Metribolone results in increased expression of CASC3 mRNA CTD PMID:17010196 NCBI chr10:83,769,014...83,788,966
Ensembl chr10:83,769,001...83,788,966
JBrowse link
G Cbl Cbl proto-oncogene increases expression ISO Metribolone results in increased expression of CBL mRNA CTD PMID:16301331 NCBI chr 8:44,487,824...44,571,620
Ensembl chr 8:44,489,410...44,571,176
JBrowse link
G Ccna2 cyclin A2 increases expression ISO Metribolone results in increased expression of CCNA2 mRNA CTD PMID:19318562 NCBI chr 2:119,427,239...119,433,645
Ensembl chr 2:119,426,089...119,433,577
JBrowse link
G Cd200 Cd200 molecule decreases expression ISO Metribolone results in decreased expression of CD200 mRNA CTD PMID:17010675 NCBI chr11:55,410,166...55,437,527
Ensembl chr11:55,410,196...55,501,648
JBrowse link
G Cdc6 cell division cycle 6 increases expression ISO Metribolone results in increased expression of CDC6 mRNA CTD PMID:19318562 NCBI chr10:83,864,189...83,878,011
Ensembl chr10:83,864,638...83,878,011
JBrowse link
G Cdh1 cadherin 1 affects localization ISO Metribolone affects the localization of CDH1 protein CTD PMID:17440980 NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775
JBrowse link
G Cdk2ap1 cyclin-dependent kinase 2 associated protein 1 increases expression ISO Metribolone results in increased expression of CDK2AP1 mRNA CTD PMID:17010196 NCBI chr12:32,249,752...32,258,483
Ensembl chr12:32,249,747...32,258,479
JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A increases expression ISO Metribolone results in increased expression of CDKN2A protein CTD PMID:23272087 NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149
JBrowse link
G Cenpn centromere protein N increases expression ISO Metribolone results in increased expression of CENPN mRNA CTD PMID:17010675 NCBI chr19:44,971,265...44,994,019
Ensembl chr19:44,968,308...44,994,012
JBrowse link
G Chd9 chromodomain helicase DNA binding protein 9 multiple interactions ISO [Metribolone binds to and affects the folding of AR protein] inhibits the reaction [AR protein modified form binds to CHD9 protein modified form] CTD PMID:28751236 NCBI chr19:15,941,535...16,146,220
Ensembl chr19:15,942,687...16,164,556
JBrowse link
G Chek1 checkpoint kinase 1 increases expression
increases phosphorylation
ISO Metribolone results in increased expression of CHEK1 mRNA
Metribolone results in increased phosphorylation of CHEK1 protein
CTD PMID:19318562 PMID:23272087 NCBI chr 8:36,420,565...36,443,477
Ensembl chr 8:36,420,569...36,441,009
JBrowse link
G Chek2 checkpoint kinase 2 multiple interactions
increases phosphorylation
ISO [Curcumin co-treated with Metribolone] results in increased phosphorylation of CHEK2 protein
Metribolone results in increased phosphorylation of CHEK2 protein
CTD PMID:21134073 PMID:23272087 NCBI chr12:45,788,823...45,821,382
Ensembl chr12:45,788,827...45,821,286
JBrowse link
G Cilk1 ciliogenesis associated kinase 1 increases expression ISO Metribolone results in increased expression of CILK1 mRNA CTD PMID:17010196 NCBI chr 8:78,984,075...79,042,695
Ensembl chr 8:78,984,258...79,042,691
JBrowse link
G Ckb creatine kinase B increases expression ISO Metribolone results in increased expression of CKB protein CTD PMID:17152098 NCBI chr 6:130,729,420...130,732,301
Ensembl chr 6:130,729,423...130,732,315
JBrowse link
G Cldn3 claudin 3 increases expression ISO Metribolone results in increased expression of CLDN3 mRNA CTD PMID:17010196 NCBI chr12:21,708,538...21,710,010
Ensembl chr12:21,708,398...21,711,001
JBrowse link
G Cltc clathrin heavy chain multiple interactions ISO Metribolone promotes the reaction [NDRG1 protein binds to CLTC protein] CTD PMID:17220478 NCBI chr10:71,517,661...71,574,591
Ensembl chr10:71,517,663...71,573,737
JBrowse link
G Clu clusterin decreases expression
multiple interactions
increases expression
ISO Metribolone results in decreased expression of CLU mRNA alternative form
bicalutamide inhibits the reaction [Metribolone results in increased expression of CLU mRNA]; bicalutamide inhibits the reaction [Metribolone results in increased expression of CLU protein]; Metribolone promotes the reaction [AR protein binds to CLU enhancer]
Metribolone results in increased expression of CLU mRNA; Metribolone results in increased expression of CLU mRNA alternative form; Metribolone results in increased expression of CLU protein
CTD PMID:17010196 PMID:17148459 PMID:17325745 NCBI chr15:40,161,068...40,200,315
Ensembl chr15:40,174,617...40,200,315
JBrowse link
G Cndp2 carnosine dipeptidase 2 multiple interactions
increases expression
ISO Metribolone promotes the reaction [NDRG1 protein binds to CNDP2 protein]
Metribolone results in increased expression of CNDP2 protein
CTD PMID:17152098 PMID:17220478 NCBI chr18:78,039,924...78,057,030
Ensembl chr18:78,039,932...78,056,922
JBrowse link
G Cnot1 CCR4-NOT transcription complex, subunit 1 multiple interactions ISO [Metribolone binds to and affects the folding of AR protein] affects the reaction [AR protein modified form binds to CNOT1 protein modified form] CTD PMID:28751236 NCBI chr19:9,255,190...9,346,574
Ensembl chr19:9,255,194...9,346,574
JBrowse link
G Copb2 COPI coat complex subunit beta 2 multiple interactions ISO Metribolone promotes the reaction [NDRG1 protein binds to COPB2 protein] CTD PMID:17220478 NCBI chr 8:99,161,324...99,183,452
Ensembl chr 8:99,161,350...99,185,197
JBrowse link
G Creb1 cAMP responsive element binding protein 1 increases phosphorylation
multiple interactions
EXP Metribolone results in increased phosphorylation of CREB1 protein
RTKI cpd inhibits the reaction [Metribolone results in increased phosphorylation of CREB1 protein]
CTD PMID:17272394 NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816
JBrowse link
G Crebbp CREB binding protein multiple interactions
decreases expression
ISO [Metribolone binds to and affects the folding of AR protein] promotes the reaction [AR protein modified form binds to CREBBP protein modified form]; bicalutamide inhibits the reaction [Metribolone results in decreased expression of CREBBP protein]; Metribolone inhibits the reaction [CREBBP protein results in increased activity of AR protein]
Metribolone results in decreased expression of CREBBP mRNA; Metribolone results in decreased expression of CREBBP protein
CTD PMID:11981028 PMID:15378487 PMID:28751236 NCBI chr10:11,335,551...11,461,888
Ensembl chr10:11,335,953...11,461,888
JBrowse link
G Crls1 cardiolipin synthase 1 increases expression ISO Metribolone results in increased expression of CRLS1 mRNA CTD PMID:16751804 NCBI chr 3:120,119,822...120,138,674
Ensembl chr 3:120,119,852...120,138,655
JBrowse link
G Csnk1a1 casein kinase 1, alpha 1 affects splicing ISO Metribolone affects the splicing of CSNK1A1 mRNA CTD PMID:17010196 NCBI chr18:55,017,049...55,050,184
Ensembl chr18:55,017,055...55,049,271
JBrowse link
G Ctnnb1 catenin beta 1 multiple interactions ISO Metribolone promotes the reaction [NDRG1 protein binds to CTNNB1 protein] CTD PMID:17220478 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111
JBrowse link
G Ctsb cathepsin B decreases expression ISO Metribolone results in decreased expression of CTSB protein CTD PMID:17152098 NCBI chr15:37,389,636...37,410,508
Ensembl chr15:37,389,629...37,410,500
JBrowse link
G Ctsd cathepsin D decreases expression ISO Metribolone results in decreased expression of CTSD protein CTD PMID:17152098 NCBI chr 1:197,527,467...197,539,343
Ensembl chr 1:197,527,467...197,539,488
JBrowse link
G Cwc27 CWC27 spliceosome associated cyclophilin increases expression ISO Metribolone results in increased expression of CWC27 mRNA CTD PMID:17010196 NCBI chr 2:35,764,674...35,975,908
Ensembl chr 2:35,764,686...35,975,872
JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 increases expression
multiple interactions
ISO Metribolone results in increased expression of CXCR4 mRNA
Dapsone analog inhibits the reaction [Metribolone results in increased expression of CXCR4 mRNA]
CTD PMID:21440447 NCBI chr13:40,077,976...40,081,883
Ensembl chr13:40,077,976...40,081,883
JBrowse link
G Dars1 aspartyl-tRNA synthetase 1 multiple interactions ISO Metribolone promotes the reaction [NDRG1 protein binds to DARS1 protein] CTD PMID:17220478 NCBI chr13:39,857,936...39,913,055
Ensembl chr13:39,857,936...39,913,116
JBrowse link
G Dcun1d1 defective in cullin neddylation 1 domain containing 1 decreases expression ISO Metribolone results in decreased expression of DCUN1D1 protein CTD PMID:17152098 NCBI chr 2:118,721,275...118,772,606
Ensembl chr 2:118,721,822...118,772,602
JBrowse link
G Ddx1 DEAD-box helicase 1 multiple interactions ISO Metribolone promotes the reaction [NDRG1 protein binds to DDX1 protein] CTD PMID:17220478 NCBI chr 6:35,996,469...36,027,340
Ensembl chr 6:35,996,469...36,027,365
JBrowse link
G Ddx5 DEAD-box helicase 5 multiple interactions ISO Metribolone promotes the reaction [NDRG1 protein binds to DDX5 protein] CTD PMID:17220478 NCBI chr10:91,723,508...91,732,210
Ensembl chr10:91,723,508...91,732,283
JBrowse link
G Dek DEK proto-oncogene increases expression ISO Metribolone results in increased expression of DEK mRNA; Metribolone results in increased expression of DEK protein CTD PMID:23071688 NCBI chr17:17,580,804...17,602,825
Ensembl chr17:17,580,843...17,602,808
JBrowse link
G Dhx30 DExH-box helicase 30 multiple interactions ISO [Metribolone binds to and affects the folding of AR protein] inhibits the reaction [AR protein modified form binds to DHX30 protein modified form] CTD PMID:28751236 NCBI chr 8:110,064,751...110,096,954
Ensembl chr 8:110,064,752...110,097,381
JBrowse link
G Dlg5 discs large MAGUK scaffold protein 5 increases expression ISO Metribolone results in increased expression of DLG5 mRNA CTD PMID:17010196 NCBI chr15:75,786...209,735
Ensembl chr15:75,786...187,837
JBrowse link
G Dlst dihydrolipoamide S-succinyltransferase multiple interactions ISO Metribolone promotes the reaction [NDRG1 protein binds to DLST protein] CTD PMID:17220478 NCBI chr 6:104,758,511...104,783,296
Ensembl chr 6:104,758,631...104,783,296
JBrowse link
G Drd4 dopamine receptor D4 multiple interactions ISO Metribolone inhibits the reaction [Ketoconazole results in decreased expression of DRD4 mRNA] CTD PMID:19587329 NCBI chr 1:196,396,366...196,400,824
Ensembl chr 1:196,396,366...196,399,553
JBrowse link
G Dynll2 dynein light chain LC8-type 2 increases expression ISO Metribolone results in increased expression of DYNLL2 mRNA CTD PMID:16751804 NCBI chr10:72,767,035...72,785,824
Ensembl chr10:72,767,035...72,785,805
JBrowse link
G Eaf2 ELL associated factor 2 increases expression ISO Metribolone results in increased expression of EAF2 mRNA CTD PMID:17010675 NCBI chr11:63,960,200...64,004,610
Ensembl chr11:63,960,200...64,004,610
JBrowse link
G Ebag9 estrogen receptor binding site associated antigen 9 increases expression ISO Metribolone results in increased expression of EBAG9 mRNA CTD PMID:17010196 NCBI chr 7:75,810,950...75,828,902
Ensembl chr 7:75,810,594...75,861,248
JBrowse link
G Eef1g eukaryotic translation elongation factor 1 gamma multiple interactions ISO Metribolone promotes the reaction [NDRG1 protein binds to EEF1G protein] CTD PMID:17220478 NCBI chr 1:205,860,713...205,871,319
Ensembl chr 1:205,860,698...205,872,382
JBrowse link
G Eef2 eukaryotic translation elongation factor 2 multiple interactions
increases expression
ISO Metribolone promotes the reaction [NDRG1 protein binds to EEF2 protein]
Metribolone results in increased expression of EEF2 protein
CTD PMID:17152098 PMID:17220478 NCBI chr 7:8,533,248...8,538,518
Ensembl chr 7:8,533,116...8,559,183
JBrowse link
G Egfr epidermal growth factor receptor multiple interactions EXP Metribolone results in increased phosphorylation of and results in increased activity of EGFR protein CTD PMID:17272394 NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382
JBrowse link
G Eif2s3 eukaryotic translation initiation factor 2 subunit gamma multiple interactions ISO Metribolone promotes the reaction [NDRG1 protein binds to EIF2S3 protein] CTD PMID:17220478 NCBI chr  X:58,916,513...58,939,923
Ensembl chr  X:58,917,490...58,940,686
JBrowse link
G Eif3e eukaryotic translation initiation factor 3 subunit E multiple interactions ISO Metribolone promotes the reaction [NDRG1 protein binds to EIF3E protein] CTD PMID:17220478 NCBI chr 7:74,339,848...74,372,483
Ensembl chr 7:74,339,828...74,373,096
JBrowse link
G Eif3k eukaryotic translation initiation factor 3, subunit K affects splicing ISO Metribolone affects the splicing of EIF3K mRNA CTD PMID:17010196 NCBI chr 1:84,260,127...84,270,051
Ensembl chr 1:84,259,673...84,270,302
JBrowse link
G Elac2 elaC ribonuclease Z 2 increases expression ISO Metribolone results in increased expression of ELAC2 mRNA CTD PMID:17010196 NCBI chr10:49,632,308...49,655,614
Ensembl chr10:49,632,378...49,655,614
JBrowse link
G Elk4 ETS transcription factor ELK4 multiple interactions
increases expression
ISO Dapsone analog inhibits the reaction [Metribolone results in increased expression of ELK4 mRNA] CTD PMID:21440447 NCBI chr13:43,451,130...43,475,035
Ensembl chr13:43,435,843...43,475,035
JBrowse link
G Ell2 elongation factor for RNA polymerase II 2 increases expression ISO Metribolone results in increased expression of ELL2 mRNA CTD PMID:16751804 PMID:17010675 NCBI chr 2:5,189,375...5,258,781
Ensembl chr 2:5,189,971...5,258,781
JBrowse link
G Eno2 enolase 2 decreases expression ISO Metribolone results in decreased expression of ENO2 protein CTD PMID:17152098 NCBI chr 4:157,572,085...157,580,971
Ensembl chr 4:157,572,088...157,580,980
JBrowse link
G Entr1 endosome associated trafficking regulator 1 increases expression ISO Metribolone results in increased expression of ENTR1 mRNA CTD PMID:17010196 NCBI chr 3:9,200,967...9,207,688
Ensembl chr 3:9,200,967...9,207,688
JBrowse link
G Ep300 E1A binding protein p300 multiple interactions ISO [Metribolone binds to and affects the folding of AR protein] affects the reaction [AR protein modified form binds to EP300 protein modified form] CTD PMID:28751236 NCBI chr 7:113,108,476...113,178,529
Ensembl chr 7:113,106,247...113,136,088
Ensembl chr 7:113,106,247...113,136,088
JBrowse link
G Ephx2 epoxide hydrolase 2 increases expression ISO Metribolone results in increased expression of EPHX2 protein CTD PMID:17152098 NCBI chr15:40,289,901...40,327,632
Ensembl chr15:40,289,902...40,327,615
JBrowse link
G Eppin epididymal peptidase inhibitor multiple interactions ISO Metribolone inhibits the reaction [Ketoconazole results in decreased expression of EPPIN mRNA] CTD PMID:19587329 NCBI chr 3:153,312,396...153,319,310
Ensembl chr 3:153,312,396...153,319,310
JBrowse link
G Erg ETS transcription factor ERG multiple interactions ISO [ATM mutant form inhibits the reaction [Metribolone results in increased expression of H2AX protein]] which results in increased expression of ERG mRNA CTD PMID:23272087 NCBI chr11:34,678,614...34,900,951
Ensembl chr11:34,678,618...34,845,871
JBrowse link
G Ergic3 ERGIC and golgi 3 increases expression ISO Metribolone results in increased expression of ERGIC3 mRNA CTD PMID:17010196 NCBI chr 3:144,525,059...144,534,813
Ensembl chr 3:144,525,092...144,534,813
JBrowse link
G Erp44 endoplasmic reticulum protein 44 increases expression ISO Metribolone results in increased expression of ERP44 protein CTD PMID:17152098 NCBI chr 5:62,516,550...62,610,762
Ensembl chr 5:62,516,551...62,610,761
JBrowse link
G Evi5 ecotropic viral integration site 5 increases expression ISO Metribolone results in increased expression of EVI5 mRNA CTD PMID:16751804 NCBI chr14:1,875,601...2,021,678
Ensembl chr14:1,875,647...2,021,678
JBrowse link
G Ewsr1 EWS RNA-binding protein 1 multiple interactions ISO Metribolone promotes the reaction [NDRG1 protein binds to EWSR1 protein] CTD PMID:17220478 NCBI chr14:79,965,365...79,994,108
Ensembl chr14:79,965,368...79,994,544
JBrowse link
G Ezr ezrin multiple interactions
increases phosphorylation
increases expression
ISO bicalutamide inhibits the reaction [Metribolone results in increased expression of EZR mRNA]; bicalutamide inhibits the reaction [Metribolone results in increased phosphorylation of EZR protein]; Metribolone promotes the reaction [EZR protein binds to PRKCA protein]; PRKCA protein affects the reaction [Metribolone results in increased phosphorylation of EZR protein] CTD PMID:16873375 NCBI chr 1:46,967,961...47,011,505
Ensembl chr 1:46,967,658...47,011,505
JBrowse link
G Fads1 fatty acid desaturase 1 increases expression ISO Metribolone results in increased expression of FADS1 mRNA CTD PMID:16751804 NCBI chr 1:206,827,724...206,842,734
Ensembl chr 1:206,827,765...206,842,734
JBrowse link
G Fasn fatty acid synthase increases expression
multiple interactions
ISO Metribolone results in increased expression of FASN protein
Metribolone promotes the reaction [NDRG1 protein binds to FASN protein]
CTD PMID:17152098 PMID:17220478 NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261
JBrowse link
G Fdft1 farnesyl diphosphate farnesyl transferase 1 increases expression ISO Metribolone results in increased expression of FDFT1 mRNA; Metribolone results in increased expression of FDFT1 protein CTD PMID:17483544 NCBI chr15:37,412,143...37,440,198
Ensembl chr15:37,412,146...37,440,287
JBrowse link
G Fkbp5 FKBP prolyl isomerase 5 multiple interactions
increases expression
ISO Dapsone analog inhibits the reaction [Metribolone results in increased expression of FKBP5 mRNA]
Metribolone results in increased expression of FKBP5 mRNA; Metribolone results in increased expression of FKBP5 protein
CTD PMID:16751804 PMID:17010675 PMID:17152098 PMID:21440447 NCBI chr20:6,457,207...6,575,404
Ensembl chr20:6,457,216...6,541,674
JBrowse link
G Fkbp8 FKBP prolyl isomerase 8 decreases expression ISO Metribolone results in decreased expression of FKBP8 protein CTD PMID:17152098 NCBI chr16:18,895,608...18,902,648
Ensembl chr16:18,893,576...18,902,612
JBrowse link
G Folh1 folate hydrolase 1 multiple interactions
decreases expression
ISO 1,2-dibromo-4-(1,2-dibromoethyl)cyclohexane analog inhibits the reaction [Metribolone results in decreased expression of FOLH1 mRNA]; [Metribolone co-treated with tris(1,3-dichloro-2-propyl)phosphate] affects the expression of FOLH1 mRNA; [Metribolone co-treated with tris(1,3-dichloro-2-propyl)phosphate] affects the expression of FOLH1 protein; DDT inhibits the reaction [Metribolone results in decreased expression of FOLH1 mRNA]; DDT inhibits the reaction [Metribolone results in decreased expression of FOLH1 protein]; Dichlorodiphenyl Dichloroethylene inhibits the reaction [Metribolone results in decreased expression of FOLH1 mRNA]
Metribolone results in decreased expression of FOLH1 mRNA; Metribolone results in decreased expression of FOLH1 protein
CTD PMID:12711008 PMID:17152098 PMID:25682698 PMID:26709203 PMID:26729308 NCBI chr 1:140,428,101...140,501,563
Ensembl chr 1:140,428,101...140,501,379
JBrowse link
G Fshb follicle stimulating hormone subunit beta increases expression
multiple interactions
ISO Metribolone results in increased expression of FSHB mRNA
AR protein promotes the reaction [Metribolone results in increased expression of FSHB mRNA]
CTD PMID:16675544 NCBI chr 3:93,548,560...93,552,370
Ensembl chr 3:93,548,560...93,552,370
JBrowse link
G Fth1 ferritin heavy chain 1 decreases expression ISO Metribolone results in decreased expression of FTH1 protein CTD PMID:17152098 NCBI chr 1:206,627,142...206,629,430
Ensembl chr 1:206,627,103...206,725,424
JBrowse link
G G6pd glucose-6-phosphate dehydrogenase decreases expression ISO Metribolone results in decreased expression of G6PD protein CTD PMID:17152098 NCBI chr  X:152,201,081...152,220,863
Ensembl chr  X:152,201,098...152,220,801
JBrowse link
G Ganab glucosidase II alpha subunit increases expression ISO Metribolone results in increased expression of GANAB protein CTD PMID:17152098 NCBI chr 1:205,793,910...205,813,704
Ensembl chr 1:205,793,895...205,813,695
JBrowse link
G Gdf15 growth differentiation factor 15 increases expression ISO Metribolone results in increased expression of GDF15 mRNA CTD PMID:17010196 NCBI chr16:18,804,457...18,808,043
Ensembl chr16:18,805,239...18,808,055
JBrowse link
G Gfm1 G elongation factor, mitochondrial 1 increases expression ISO Metribolone results in increased expression of GFM1 protein CTD PMID:17152098 NCBI chr 2:151,700,573...151,745,477
Ensembl chr 2:151,700,564...151,745,471
JBrowse link
G Ggct gamma-glutamyl cyclotransferase decreases expression ISO Metribolone results in decreased expression of GGCT protein CTD PMID:17152098 NCBI chr 4:84,122,921...84,129,327
Ensembl chr 4:84,123,118...84,129,277
JBrowse link
G Glod4 glyoxalase domain containing 4 decreases expression ISO Metribolone results in decreased expression of GLOD4 protein CTD PMID:17152098 NCBI chr10:61,077,535...61,095,876
Ensembl chr10:61,066,421...61,095,898
JBrowse link
G Glra2 glycine receptor, alpha 2 decreases expression ISO Metribolone results in decreased expression of GLRA2 mRNA CTD PMID:17010675 NCBI chr  X:29,020,377...29,241,666
Ensembl chr  X:29,020,557...29,241,666
JBrowse link
G Glul glutamate-ammonia ligase increases expression ISO Metribolone results in increased expression of GLUL protein CTD PMID:17152098 NCBI chr13:65,969,053...66,035,121
Ensembl chr13:66,025,630...66,035,108
JBrowse link
G Gnai3 G protein subunit alpha i3 increases expression ISO Metribolone results in increased expression of GNAI3 mRNA CTD PMID:16751804 NCBI chr 2:195,742,765...195,780,720
Ensembl chr 2:195,742,642...195,780,742
JBrowse link
G Gnaq G protein subunit alpha q multiple interactions ISO [Metribolone binds to and affects the folding of AR protein] inhibits the reaction [AR protein modified form binds to GNAQ protein modified form] CTD PMID:28751236 NCBI chr 1:213,425,631...213,671,947
Ensembl chr 1:213,424,465...213,667,672
JBrowse link
G Gnmt glycine N-methyltransferase increases expression ISO Metribolone results in increased expression of GNMT mRNA CTD PMID:17010675 NCBI chr 9:14,254,675...14,258,028
Ensembl chr 9:14,254,675...14,258,434
JBrowse link
G Golm2 golgi membrane protein 2 increases expression ISO Metribolone results in increased expression of GOLM2 mRNA CTD PMID:17010196 NCBI chr 3:108,827,017...108,896,207
Ensembl chr 3:108,827,047...108,896,207
JBrowse link
G Got2 glutamic-oxaloacetic transaminase 2 increases expression ISO Metribolone results in increased expression of GOT2 protein CTD PMID:17626249 NCBI chr19:9,174,304...9,199,995
Ensembl chr19:9,174,311...9,199,994
JBrowse link
G Gpd1 glycerol-3-phosphate dehydrogenase 1 multiple interactions ISO Metribolone inhibits the reaction [Ketoconazole results in decreased expression of GPD1 mRNA] CTD PMID:19587329 NCBI chr 7:130,842,526...130,851,530
Ensembl chr 7:130,844,138...130,851,529
JBrowse link
G Greb1 growth regulating estrogen receptor binding 1 multiple interactions
increases expression
ISO Dapsone analog inhibits the reaction [Metribolone results in increased expression of GREB1 mRNA] CTD PMID:16496412 PMID:21440447 NCBI chr 6:39,440,522...39,562,364
Ensembl chr 6:39,440,504...39,581,633
JBrowse link
G Gsn gelsolin multiple interactions ISO [Metribolone binds to and affects the folding of AR protein] promotes the reaction [AR protein modified form binds to GSN protein modified form] CTD PMID:28751236 NCBI chr 3:18,585,166...18,638,404
Ensembl chr 3:18,585,172...18,638,402
JBrowse link
G Gspt1 G1 to S phase transition 1 increases expression ISO Metribolone results in increased expression of GSPT1 protein CTD PMID:17152098 NCBI chr10:4,362,528...4,397,215
Ensembl chr10:4,362,510...4,397,198
JBrowse link
G Gss glutathione synthetase increases expression ISO Metribolone results in increased expression of GSS protein CTD PMID:17152098 NCBI chr 3:144,047,849...144,078,197
Ensembl chr 3:144,047,850...144,078,198
JBrowse link
G H2ax H2A.X variant histone multiple interactions
increases expression
ISO [ATM mutant form inhibits the reaction [Metribolone results in increased expression of H2AX protein]] which results in increased expression of ERG mRNA; [Curcumin co-treated with Metribolone] results in increased phosphorylation of H2AX protein; ATM mutant form inhibits the reaction [Metribolone results in increased expression of H2AX protein]; ATR mutant form inhibits the reaction [Metribolone results in increased expression of H2AX protein] CTD PMID:21134073 PMID:23272087 NCBI chr 8:44,671,907...44,673,262
Ensembl chr 8:44,671,786...44,673,239
JBrowse link
G Helz2 helicase with zinc finger 2 multiple interactions ISO [Metribolone binds to and affects the folding of AR protein] affects the reaction [AR protein modified form binds to HELZ2 protein modified form] CTD PMID:28751236 NCBI chr 3:168,338,813...168,353,219
Ensembl chr 3:168,338,813...168,353,159
JBrowse link
G Herc3 HECT and RLD domain containing E3 ubiquitin protein ligase 3 increases expression ISO Metribolone results in increased expression of HERC3 mRNA CTD PMID:17010675 NCBI chr 4:87,952,202...88,042,492
Ensembl chr 4:87,952,274...88,042,488
JBrowse link
G Hexb hexosaminidase subunit beta increases expression ISO Metribolone results in increased expression of HEXB mRNA CTD PMID:17010196 NCBI chr 2:28,483,997...28,504,165
Ensembl chr 2:28,484,012...28,504,223
JBrowse link
G Hibadh 3-hydroxyisobutyrate dehydrogenase decreases expression ISO Metribolone results in decreased expression of HIBADH protein CTD PMID:17152098 NCBI chr 4:81,649,180...81,747,244
Ensembl chr 4:81,649,175...81,780,617
JBrowse link
G Hid1 HID1 domain containing increases expression ISO Metribolone results in increased expression of HID1 mRNA CTD PMID:17010196 NCBI chr10:100,589,555...100,610,050
Ensembl chr10:100,589,555...100,610,041
JBrowse link
G Hmgb1 high mobility group box 1 decreases expression ISO Metribolone results in decreased expression of HMGB1 protein CTD PMID:17152098 NCBI chr12:5,972,950...5,979,658
Ensembl chr12:5,901,586...5,978,565
Ensembl chr16:5,901,586...5,978,565
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase increases expression ISO Metribolone results in increased expression of HMGCR mRNA; Metribolone results in increased expression of HMGCR protein CTD PMID:16751804 NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703
JBrowse link
G Hmgcs1 3-hydroxy-3-methylglutaryl-CoA synthase 1 increases expression ISO Metribolone results in increased expression of HMGCS1 protein CTD PMID:17152098 NCBI chr 2:51,649,368...51,667,100
Ensembl chr 2:51,649,497...51,667,100
JBrowse link
G Hnrnpc heterogeneous nuclear ribonucleoprotein C decreases expression ISO Metribolone results in decreased expression of HNRNPC protein CTD PMID:17152098 NCBI chr15:24,779,593...24,809,213
Ensembl chr15:24,779,450...24,809,183
JBrowse link
G Hnrnpf heterogeneous nuclear ribonucleoprotein F multiple interactions
increases expression
ISO Metribolone promotes the reaction [NDRG1 protein binds to HNRNPF protein]
Metribolone results in increased expression of HNRNPF protein
CTD PMID:17152098 PMID:17220478 NCBI chr 4:151,083,262...151,104,464
Ensembl chr 4:151,083,062...151,109,038
JBrowse link
G Hnrnph1 heterogeneous nuclear ribonucleoprotein H1 multiple interactions ISO Metribolone promotes the reaction [NDRG1 protein binds to HNRNPH1 protein] CTD PMID:17220478 NCBI chr10:34,692,868...34,702,849
Ensembl chr10:34,693,555...34,702,846
JBrowse link
G Hnrnph2 heterogeneous nuclear ribonucleoprotein H2 decreases expression ISO Metribolone results in decreased expression of HNRNPH2 protein CTD PMID:17152098 NCBI chr  X:97,780,890...97,786,846
Ensembl chr  X:97,780,785...97,787,041
JBrowse link
G Hnrnph3 heterogeneous nuclear ribonucleoprotein H3 decreases expression ISO Metribolone results in decreased expression of HNRNPH3 protein CTD PMID:17152098 NCBI chr20:25,616,400...25,625,814
Ensembl chr20:25,614,733...25,625,750
JBrowse link
G Hnrnpk heterogeneous nuclear ribonucleoprotein K decreases expression ISO Metribolone results in decreased expression of HNRNPK protein CTD PMID:17152098 NCBI chr17:6,262,936...6,275,001
Ensembl chr17:6,262,998...6,274,997
JBrowse link
G Hnrnpu heterogeneous nuclear ribonucleoprotein U multiple interactions ISO Metribolone promotes the reaction [NDRG1 protein binds to HNRNPU protein] CTD PMID:17220478 NCBI chr13:90,069,058...90,086,905
Ensembl chr13:90,074,181...90,086,588
JBrowse link
G Hr HR, lysine demethylase and nuclear receptor corepressor multiple interactions ISO [Metribolone binds to and affects the folding of AR protein] inhibits the reaction [AR protein modified form binds to HR protein modified form] CTD PMID:28751236 NCBI chr15:45,626,835...45,646,313
Ensembl chr15:45,626,835...45,646,313
JBrowse link
G Hsd17b4 hydroxysteroid (17-beta) dehydrogenase 4 multiple interactions ISO Metribolone promotes the reaction [NDRG1 protein binds to HSD17B4 protein] CTD PMID:17220478 NCBI chr18:43,328,903...43,417,950
Ensembl chr18:43,328,824...43,417,952
JBrowse link
G Hsf1 heat shock transcription factor 1 decreases activity ISO Metribolone results in decreased activity of HSF1 protein CTD PMID:34170685 NCBI chr 7:108,196,040...108,223,011
Ensembl chr 7:108,196,056...108,223,011
JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 multiple interactions ISO Metribolone promotes the reaction [NDRG1 protein binds to HSP90AA1 protein] CTD PMID:17220478 NCBI chr 6:129,702,376...129,707,907
Ensembl chr 6:129,702,383...129,707,268
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 affects localization
increases expression
multiple interactions
ISO Metribolone affects the localization of HSPA5 protein
Metribolone results in increased expression of HSPA5 protein
Metribolone promotes the reaction [NDRG1 protein binds to HSPA5 protein]
CTD PMID:17152098 PMID:17220478 PMID:17440980 NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891
JBrowse link
G Hspb1 heat shock protein family B (small) member 1 increases expression ISO Metribolone results in increased expression of HSPB1 protein CTD PMID:17152098 NCBI chr12:20,794,014...20,795,675
Ensembl chr12:20,794,028...20,795,743
JBrowse link
G Htra2 HtrA serine peptidase 2 decreases expression ISO Metribolone results in decreased expression of HTRA2 protein CTD PMID:17152098 NCBI chr 4:115,556,914...115,560,202
Ensembl chr 4:115,556,916...115,560,095
JBrowse link
G Hus1 HUS1 checkpoint clamp component increases expression ISO Metribolone results in increased expression of HUS1 mRNA CTD PMID:19318562 NCBI chr14:83,688,702...83,703,466
Ensembl chr14:83,688,708...83,703,442
JBrowse link
G Hyou1 hypoxia up-regulated 1 increases expression ISO Metribolone results in increased expression of HYOU1 protein CTD PMID:17152098 NCBI chr 8:44,706,073...44,718,189
Ensembl chr 8:44,706,263...44,718,186
JBrowse link
G Ide insulin degrading enzyme increases expression ISO Metribolone results in increased expression of IDE protein CTD PMID:17152098 NCBI chr 1:235,002,984...235,102,448
Ensembl chr 1:234,995,351...235,102,440
JBrowse link
G Idh1 isocitrate dehydrogenase (NADP(+)) 1 increases expression ISO Metribolone results in increased expression of IDH1 protein CTD PMID:17152098 NCBI chr 9:66,534,146...66,563,703
Ensembl chr 9:66,534,146...66,563,708
JBrowse link
G Idi1 isopentenyl-diphosphate delta isomerase 1 increases expression ISO Metribolone results in increased expression of IDI1 protein CTD PMID:17152098 NCBI chr17:61,629,592...61,637,357
Ensembl chr17:61,629,594...61,637,357
JBrowse link
G Igf1 insulin-like growth factor 1 multiple interactions
increases expression
ISO [Metribolone co-treated with tris(1,3-dichloro-2-propyl)phosphate] results in decreased expression of IGF1 mRNA; DDT affects the reaction [Metribolone results in increased expression of IGF1 mRNA]; Dichlorodiphenyl Dichloroethylene inhibits the reaction [Metribolone results in increased expression of IGF1 mRNA] CTD PMID:25682698 PMID:26709203 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296
JBrowse link
G Igf1r insulin-like growth factor 1 receptor increases expression
multiple interactions
ISO Metribolone results in increased expression of IGF1R mRNA
Dapsone analog inhibits the reaction [Metribolone results in increased expression of IGF1R mRNA]; resveratrol inhibits the reaction [Metribolone results in increased expression of IGF1R mRNA]
CTD PMID:18586690 PMID:21440447 NCBI chr 1:121,549,831...121,838,548
Ensembl chr 1:121,550,743...121,831,777
JBrowse link
G Igfbp3 insulin-like growth factor binding protein 3 multiple interactions
increases expression
ISO [Calcitriol co-treated with Metribolone] results in increased expression of IGFBP3 mRNA; Metribolone promotes the reaction [AR protein binds to IGFBP3 promoter]
Metribolone results in increased expression of IGFBP3 mRNA
CTD PMID:16825320 NCBI chr14:82,056,347...82,064,083
Ensembl chr14:82,056,347...82,064,083
JBrowse link
G Il6 interleukin 6 multiple interactions ISO IL6 protein inhibits the reaction [Metribolone results in increased activity of AR protein] CTD PMID:17219378 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Ilf3 interleukin enhancer binding factor 3 multiple interactions ISO Metribolone promotes the reaction [NDRG1 protein binds to ILF3 protein] CTD PMID:17220478 NCBI chr 8:19,922,409...19,960,495
Ensembl chr 8:19,922,460...19,960,350
JBrowse link
G Immt inner membrane mitochondrial protein increases expression ISO Metribolone results in increased expression of IMMT protein CTD PMID:17152098 NCBI chr 4:103,880,482...103,919,116
Ensembl chr 4:103,880,459...103,919,109
JBrowse link
G Insig1 insulin induced gene 1 increases expression ISO Metribolone results in increased expression of INSIG1 mRNA; Metribolone results in increased expression of INSIG1 protein CTD PMID:16751804 NCBI chr 4:7,315,494...7,323,972
Ensembl chr 4:7,315,495...7,323,952
JBrowse link
G Itga2 integrin subunit alpha 2 multiple interactions ISO Metribolone results in decreased expression of [ITGA2 protein binds to ITGB1 protein] CTD PMID:17541959 NCBI chr 2:46,520,345...46,621,487
Ensembl chr 2:46,523,948...46,621,481
JBrowse link
G Itgb1 integrin subunit beta 1 multiple interactions ISO Metribolone results in decreased expression of [ITGA2 protein binds to ITGB1 protein] CTD PMID:17541959 NCBI chr19:56,705,123...56,753,199
Ensembl chr19:56,705,171...56,753,195
JBrowse link
G Itgb3bp integrin subunit beta 3 binding protein multiple interactions ISO [Metribolone binds to and affects the folding of AR protein] inhibits the reaction [AR protein modified form binds to ITGB3BP protein modified form] CTD PMID:28751236 NCBI chr 5:114,460,217...114,525,538
Ensembl chr 5:114,460,221...114,525,704
JBrowse link
G Jmjd1c jumonji domain containing 1C multiple interactions ISO [Metribolone binds to and affects the folding of AR protein] promotes the reaction [AR protein modified form binds to JMJD1C protein modified form] CTD PMID:28751236 NCBI chr20:21,332,147...21,494,220
Ensembl chr20:21,332,147...21,463,122
JBrowse link
G Jtb jumping translocation breakpoint increases expression ISO Metribolone results in increased expression of JTB mRNA CTD PMID:17010196 NCBI chr 2:175,685,392...175,689,609
Ensembl chr 2:175,684,993...175,690,108
JBrowse link
G Kat2b lysine acetyltransferase 2B multiple interactions ISO [Metribolone binds to and affects the folding of AR protein] inhibits the reaction [AR protein modified form binds to KAT2B protein modified form] CTD PMID:28751236 NCBI chr 9:6,562,525...6,667,064
Ensembl chr 9:6,562,288...6,667,064
JBrowse link
G Kdm3a lysine demethylase 3A multiple interactions
increases expression
ISO Metribolone promotes the reaction [KDM3A protein binds to KLK3 enhancer]; Metribolone promotes the reaction [KDM3A protein binds to NKX3-1 enhancer]
Metribolone results in increased expression of KDM3A protein
CTD PMID:16603237 NCBI chr 4:103,630,907...103,675,073
Ensembl chr 4:103,630,908...103,675,073
JBrowse link
G Kif5b kinesin family member 5B multiple interactions ISO Metribolone promotes the reaction [NDRG1 protein binds to KIF5B protein] CTD PMID:17220478 NCBI chr17:51,489,904...51,527,508
Ensembl chr17:51,489,944...51,527,508
JBrowse link
G Klk1c10 kallikrein 1-related peptidase C10 increases secretion
decreases expression
increases expression
multiple interactions
ISO Metribolone results in increased secretion of KLK3 protein
Metribolone results in decreased expression of KLK3 mRNA
Metribolone results in increased expression of KLK3 mRNA; Metribolone results in increased expression of KLK3 protein
1,2-dibromo-4-(1,2-dibromoethyl)cyclohexane analog affects the reaction [Metribolone results in increased secretion of KLK3 protein]; [1,2-dibromo-4-(1,2-dibromoethyl)cyclohexane analog co-treated with Metribolone] affects the expression of KLK3 mRNA; [Metribolone binds to and results in increased activity of AR protein] which results in increased expression of KLK3 protein; [Metribolone co-treated with tris(1,3-dichloro-2-propyl)phosphate] results in decreased expression of KLK3 mRNA; AMH protein inhibits the reaction [Metribolone results in increased expression of KLK3 mRNA]; Arsenic Trioxide inhibits the reaction [Metribolone promotes the reaction [AR protein binds to KLK3 promoter]]; Arsenic Trioxide inhibits the reaction [Metribolone promotes the reaction [NCOA2 protein binds to KLK3 promoter]]; bicalutamide inhibits the reaction [[Metribolone binds to and results in increased activity of AR protein] which results in increased expression of KLK3 protein]; Curcumin inhibits the reaction [Metribolone results in increased expression of KLK3 mRNA]; Curcumin inhibits the reaction [Metribolone results in increased expression of KLK3 protein]; Cyproterone Acetate inhibits the reaction [[Metribolone binds to and results in increased activity of AR protein] which results in increased expression of KLK3 protein]; DDT inhibits the reaction [Metribolone promotes the reaction [AR protein binds to KLK3 promoter]]; DDT inhibits the reaction [Metribolone results in increased expression of KLK3 mRNA]; DDT inhibits the reaction [Metribolone results in increased expression of KLK3 protein]; Dichlorodiphenyl Dichloroethylene inhibits the reaction [Metribolone promotes the reaction [AR protein binds to KLK3 promoter]]; Dichlorodiphenyl Dichloroethylene inhibits the reaction [Metribolone results in increased expression of KLK3 mRNA]; Dichlorodiphenyl Dichloroethylene inhibits the reaction [Metribolone results in increased expression of KLK3 protein]; Metribolone affects the reaction [1,2-dibromo-4-(1,2-dibromoethyl)cyclohexane analog results in increased expression of KLK3 mRNA]; Metribolone promotes the reaction [AR protein binds to KLK3 enhancer]; Metribolone promotes the reaction [AR protein binds to KLK3 promoter]; Metribolone promotes the reaction [KDM3A protein binds to KLK3 enhancer]; Metribolone promotes the reaction [NCOA2 protein binds to KLK3 promoter]; Metribolone promotes the reaction [UXT protein binds to KLK3 promoter]; Metribolone results in increased expression of and results in increased secretion of KLK3 protein; Resveratrol inhibits the reaction [Metribolone results in increased expression of KLK3 mRNA]; Resveratrol inhibits the reaction [Metribolone results in increased expression of KLK3 protein]; Sodium Selenite inhibits the reaction [Metribolone results in increased expression of KLK3 protein]; tris(1,3-dichloro-2-propyl)phosphate inhibits the reaction [Metribolone results in increased expression of KLK3 mRNA]; tris(1,3-dichloro-2-propyl)phosphate inhibits the reaction [Metribolone results in increased expression of KLK3 protein]; UXT protein affects the reaction [Metribolone results in increased expression of KLK3 mRNA]
CTD PMID:12711008 PMID:15336702 PMID:15950459 PMID:16603237 PMID:16740653 More... NCBI chr 1:94,402,993...94,407,052
Ensembl chr 1:94,402,993...94,407,052
JBrowse link
G Knl1 kinetochore scaffold 1 increases expression ISO Metribolone results in increased expression of KNL1 mRNA CTD PMID:17010196 NCBI chr 3:106,029,627...106,091,915
Ensembl chr 3:106,029,661...106,091,915
JBrowse link
G Krt1 keratin 1 decreases expression ISO Metribolone results in decreased expression of KRT1 protein CTD PMID:17152098 NCBI chr 7:132,976,618...132,981,844
Ensembl chr 7:132,976,620...132,981,844
JBrowse link
G Krt10 keratin 10 decreases expression ISO Metribolone results in decreased expression of KRT10 protein CTD PMID:17152098 NCBI chr10:84,338,695...84,343,279
Ensembl chr10:84,338,706...84,343,701
JBrowse link
G Krt18 keratin 18 increases expression ISO Metribolone results in increased expression of KRT18 protein CTD PMID:17152098 PMID:17541959 NCBI chr 7:133,157,486...133,161,162
Ensembl chr 7:133,157,475...133,161,166
JBrowse link
G Krt8 keratin 8 increases expression ISO Metribolone results in increased expression of KRT8 mRNA; Metribolone results in increased expression of KRT8 protein CTD PMID:17010196 PMID:17152098 NCBI chr 7:133,124,203...133,131,656
Ensembl chr 7:133,124,203...133,131,728
JBrowse link
G Lcor ligand dependent nuclear receptor corepressor multiple interactions ISO [Metribolone binds to and affects the folding of AR protein] promotes the reaction [AR protein modified form binds to LCOR protein modified form] CTD PMID:28751236 NCBI chr 1:240,298,565...240,405,627
Ensembl chr 1:240,298,563...240,402,448
JBrowse link
G Ldha lactate dehydrogenase A multiple interactions ISO Metribolone promotes the reaction [NDRG1 protein binds to LDHA protein] CTD PMID:17220478 NCBI chr 1:97,371,823...97,381,247
Ensembl chr 1:97,366,021...97,433,472
JBrowse link
G Ldhd lactate dehydrogenase D increases expression ISO Metribolone results in increased expression of LDHD protein CTD PMID:17152098 NCBI chr19:39,583,529...39,588,397
Ensembl chr19:39,573,621...39,595,575
JBrowse link
G Ldlr low density lipoprotein receptor affects localization ISO Metribolone affects the localization of LDLR protein CTD PMID:17440980 NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580
JBrowse link
G Lgals8 galectin 8 increases expression ISO Metribolone results in increased expression of LGALS8 mRNA CTD PMID:17010196 NCBI chr17:58,024,652...58,052,764
Ensembl chr17:58,028,105...58,052,764
JBrowse link
G Lhb luteinizing hormone subunit beta decreases expression ISO Metribolone results in decreased expression of LHB mRNA CTD PMID:16675544 NCBI chr 1:95,898,269...95,901,973
Ensembl chr 1:95,900,984...95,901,972
Ensembl chr 1:95,900,984...95,901,972
JBrowse link
G Lhpp phospholysine phosphohistidine inorganic pyrophosphate phosphatase affects splicing ISO Metribolone affects the splicing of LHPP mRNA CTD PMID:17010196 NCBI chr 1:187,403,390...187,494,577
Ensembl chr 1:187,403,433...187,494,578
JBrowse link
G Lmna lamin A/C decreases expression ISO Metribolone results in decreased expression of LMNA protein CTD PMID:17152098 NCBI chr 2:173,939,751...173,960,423
Ensembl chr 2:173,939,751...173,960,423
JBrowse link
G Lratd2 LRAT domain containing 2 increases expression ISO Metribolone results in increased expression of LRATD2 mRNA CTD PMID:17010196 NCBI chr 7:92,376,713...92,387,045
Ensembl chr 7:92,362,194...92,388,189
JBrowse link
G Lsm1 LSM1 homolog, mRNA degradation associated increases expression ISO Metribolone results in increased expression of LSM1 mRNA CTD PMID:17010196 NCBI chr16:66,277,345...66,288,852
Ensembl chr16:66,277,345...66,288,852
JBrowse link
G Lta4h leukotriene A4 hydrolase increases expression ISO Metribolone results in increased expression of LTA4H protein CTD PMID:17152098 NCBI chr 7:27,969,796...28,001,600
Ensembl chr 7:27,969,789...28,001,600
JBrowse link
G Mad1l1 mitotic arrest deficient 1 like 1 decreases expression ISO Metribolone results in decreased expression of MAD1L1 protein CTD PMID:17152098 NCBI chr12:14,320,892...14,630,750
Ensembl chr12:14,320,892...14,630,703
JBrowse link
G Maf MAF bZIP transcription factor multiple interactions
increases expression
ISO Dapsone analog inhibits the reaction [Metribolone results in increased expression of MAF mRNA] CTD PMID:16751804 PMID:17010675 PMID:21440447 NCBI chr19:43,353,867...43,713,162
Ensembl chr19:43,360,342...43,712,365
JBrowse link
G Maged2 MAGE family member D2 increases expression ISO Metribolone results in increased expression of MAGED2 mRNA CTD PMID:17010196 NCBI chr  X:19,733,593...19,741,769
Ensembl chr  X:19,733,597...19,740,477
JBrowse link
G Mak male germ cell-associated kinase multiple interactions
increases expression
ISO Dapsone analog inhibits the reaction [Metribolone results in increased expression of MAK mRNA] CTD PMID:21440447 NCBI chr17:23,683,753...23,731,125
Ensembl chr17:23,693,878...23,730,001
JBrowse link
G Man1a1 mannosidase, alpha, class 1A, member 1 decreases expression ISO Metribolone results in decreased expression of MAN1A1 mRNA CTD PMID:17010675 NCBI chr20:33,202,509...33,385,747
Ensembl chr20:33,202,517...33,385,824
JBrowse link
G Maoa monoamine oxidase A multiple interactions ISO Metribolone promotes the reaction [NDRG1 protein binds to MAOA protein] CTD PMID:17220478 NCBI chr  X:6,032,172...6,098,308
Ensembl chr  X:6,030,795...6,099,593
JBrowse link
G Map7 microtubule-associated protein 7 increases expression ISO Metribolone results in increased expression of MAP7 mRNA CTD PMID:16751804 NCBI chr 1:14,910,433...15,037,574
Ensembl chr 1:14,910,551...15,037,574
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
increases phosphorylation
EXP RTKI cpd inhibits the reaction [Metribolone results in increased phosphorylation of MAPK1 protein] CTD PMID:17272394 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 increases phosphorylation
multiple interactions
EXP Metribolone results in increased phosphorylation of MAPK3 protein
RTKI cpd inhibits the reaction [Metribolone results in increased phosphorylation of MAPK3 protein]
CTD PMID:17272394 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Mapre2 microtubule-associated protein, RP/EB family, member 2 decreases expression ISO Metribolone results in decreased expression of MAPRE2 mRNA CTD PMID:17010675 NCBI chr18:15,028,675...15,169,553
Ensembl chr18:15,029,041...15,168,044
JBrowse link
G Mcc MCC regulator of WNT signaling pathway increases expression ISO Metribolone results in increased expression of MCC mRNA CTD PMID:17010196 NCBI chr18:36,794,206...37,266,237
Ensembl chr18:36,798,372...37,266,819
JBrowse link
G Med1 mediator complex subunit 1 multiple interactions ISO [Metribolone binds to and affects the folding of AR protein] promotes the reaction [AR protein modified form binds to MED1 protein modified form] CTD PMID:28751236 NCBI chr10:83,145,538...83,189,260
Ensembl chr10:83,145,568...83,189,299
JBrowse link
G Med18 mediator complex subunit 18 affects splicing ISO Metribolone affects the splicing of MED18 mRNA CTD PMID:17010196 NCBI chr 5:144,663,316...144,668,652
Ensembl chr 5:144,663,252...144,668,635
JBrowse link
G Med28 mediator complex subunit 28 increases expression ISO Metribolone results in increased expression of MED28 mRNA CTD PMID:16751804 PMID:17010675 NCBI chr14:65,594,785...65,603,583
Ensembl chr14:65,594,647...65,603,583
JBrowse link
G Men1 menin 1 multiple interactions ISO [Metribolone binds to and affects the folding of AR protein] inhibits the reaction [AR protein modified form binds to MEN1 protein modified form] CTD PMID:28751236 NCBI chr 1:203,638,905...203,644,871
Ensembl chr 1:203,639,000...203,644,871
JBrowse link
G Mgmt O-6-methylguanine-DNA methyltransferase multiple interactions ISO [Metribolone binds to and affects the folding of AR protein] inhibits the reaction [AR protein modified form binds to MGMT protein modified form] CTD PMID:28751236 NCBI chr 1:191,710,980...191,937,760
Ensembl chr 1:191,710,930...191,937,756
JBrowse link
G Mir204 microRNA 204 decreases expression
multiple interactions
ISO Metribolone results in decreased expression of MIR204 mRNA
AR protein affects the reaction [Metribolone results in decreased expression of MIR204 mRNA]; MIR204 mRNA inhibits the reaction [Metribolone results in increased expression of XRN1 protein]
CTD PMID:25797256 NCBI chr 1:220,316,931...220,317,040
Ensembl chr 1:220,316,931...220,317,040
JBrowse link
G Mme membrane metallo-endopeptidase multiple interactions ISO Metribolone promotes the reaction [NDRG1 protein binds to MME protein] CTD PMID:17220478 NCBI chr 2:147,686,913...147,803,808
Ensembl chr 2:147,722,086...147,803,792
JBrowse link
G Mmp1 matrix metallopeptidase 1 multiple interactions ISO Metribolone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP1 mRNA] CTD PMID:8798622 NCBI chr 8:4,658,588...4,679,099
Ensembl chr 8:4,658,588...4,679,097
JBrowse link
G Mmp16 matrix metallopeptidase 16 decreases expression ISO Metribolone results in decreased expression of MMP16 mRNA CTD PMID:16751804 NCBI chr 5:31,312,280...31,556,276
Ensembl chr 5:31,312,280...31,548,388
JBrowse link
G Mmp2 matrix metallopeptidase 2 increases expression
multiple interactions
ISO Metribolone results in increased expression of MMP2 mRNA
bicalutamide inhibits the reaction [Metribolone results in increased expression of MMP2 mRNA]
CTD PMID:16888681 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870
JBrowse link
G Mmp3 matrix metallopeptidase 3 multiple interactions ISO Metribolone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP3 mRNA] CTD PMID:8798622 NCBI chr 8:4,640,397...4,653,963
Ensembl chr 8:4,640,416...4,653,961
JBrowse link
G Mphosph9 M-phase phosphoprotein 9 increases expression ISO Metribolone results in increased expression of MPHOSPH9 mRNA CTD PMID:17010675 NCBI chr12:32,275,449...32,346,097
Ensembl chr12:32,275,558...32,342,392
JBrowse link
G Mrps11 mitochondrial ribosomal protein S11 increases expression ISO Metribolone results in increased expression of MRPS11 mRNA CTD PMID:17010196 NCBI chr 1:132,707,601...132,717,253
Ensembl chr 1:132,680,420...132,717,253
JBrowse link
G Mt-atp6 mitochondrially encoded ATP synthase membrane subunit 6 increases expression ISO Metribolone results in increased expression of ATP6 mRNA CTD PMID:17010196 NCBI chr MT:7,919...8,599
NCBI chr MT:7,919...8,599
NCBI chr MT:7,919...8,599
NCBI chr MT:7,919...8,599
NCBI chr MT:7,919...8,599
NCBI chr MT:7,919...8,599
NCBI chr MT:7,919...8,599
NCBI chr MT:7,919...8,599
NCBI chr MT:7,919...8,599
Ensembl chr MT:7,919...8,599
JBrowse link
G Mt-co1 mitochondrially encoded cytochrome c oxidase I increases expression ISO Metribolone results in increased expression of COX1 mRNA CTD PMID:17010196 NCBI chr MT:5,323...6,867
NCBI chr MT:5,323...6,867
NCBI chr MT:5,323...6,867
NCBI chr MT:5,323...6,867
NCBI chr MT:5,323...6,867
NCBI chr MT:5,323...6,867
NCBI chr MT:5,323...6,867
NCBI chr MT:5,323...6,867
NCBI chr MT:5,323...6,867
Ensembl chr MT:5,323...6,867
JBrowse link
G Mt-co3 mitochondrially encoded cytochrome c oxidase III increases expression ISO Metribolone results in increased expression of COX3 mRNA CTD PMID:17010196 NCBI chr MT:8,599...9,382
NCBI chr MT:8,599...9,382
NCBI chr MT:8,599...9,382
NCBI chr MT:8,599...9,382
NCBI chr MT:8,599...9,382
NCBI chr MT:8,599...9,382
NCBI chr MT:8,599...9,382
NCBI chr MT:8,599...9,382
NCBI chr MT:8,599...9,382
Ensembl chr MT:8,599...9,382
JBrowse link
G Mt-nd2 mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 2 increases expression ISO Metribolone results in increased expression of ND2 mRNA CTD PMID:17010196 NCBI chr MT:3,904...4,942
NCBI chr MT:3,904...4,942
NCBI chr MT:3,904...4,942
NCBI chr MT:3,904...4,942
NCBI chr MT:3,904...4,942
NCBI chr MT:3,904...4,942
NCBI chr MT:3,904...4,942
NCBI chr MT:3,904...4,942
NCBI chr MT:3,904...4,942
NCBI chr MT:3,904...4,942
NCBI chr MT:3,904...4,942
Ensembl chr MT:3,904...4,942
JBrowse link
G Mt-nd4 mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 4 affects splicing
increases expression
ISO Metribolone affects the splicing of ND4 mRNA
Metribolone results in increased expression of ND4 mRNA
CTD PMID:17010196 NCBI chr MT:10,160...11,537
NCBI chr MT:10,160...11,537
NCBI chr MT:10,160...11,537
NCBI chr MT:10,160...11,537
NCBI chr MT:10,160...11,537
NCBI chr MT:10,160...11,537
NCBI chr MT:10,160...11,537
NCBI chr MT:10,160...11,537
NCBI chr MT:10,160...11,537
NCBI chr MT:10,160...11,537
NCBI chr MT:10,160...11,537
Ensembl chr MT:10,160...11,537
JBrowse link
G Mt3 metallothionein 3 increases expression ISO Metribolone results in increased expression of MT3 mRNA; Metribolone results in increased expression of MT3 protein CTD PMID:23794209 NCBI chr19:10,848,754...10,850,158
Ensembl chr19:10,848,755...10,850,158
JBrowse link
G Mterf4 mitochondrial transcription termination factor 4 increases expression ISO Metribolone results in increased expression of MTERF4 mRNA CTD PMID:16751804 NCBI chr 9:93,834,162...93,838,838
Ensembl chr 9:93,834,144...93,838,864
JBrowse link
G Mtnap1 mitochondrial nucleoid associated protein 1 increases expression ISO Metribolone results in increased expression of MTNAP1 mRNA CTD PMID:17010196 NCBI chr10:98,728,661...98,738,693
Ensembl chr10:98,727,763...98,738,691
JBrowse link
G Myl6b myosin light chain 6B affects splicing ISO Metribolone affects the splicing of MYL6B mRNA CTD PMID:17010196 NCBI chr  X:40,572,012...40,572,991 JBrowse link
G Naa15 N(alpha)-acetyltransferase 15, NatA auxiliary subunit increases expression ISO Metribolone results in increased expression of NAA15 mRNA CTD PMID:17010196 NCBI chr 2:135,458,018...135,520,756
Ensembl chr 2:135,457,948...135,520,756
JBrowse link
G Nans N-acetylneuraminate synthase increases expression ISO Metribolone results in increased expression of NANS protein CTD PMID:17152098 NCBI chr 5:60,780,441...60,797,583
Ensembl chr 5:60,780,392...60,814,950
JBrowse link
G Napa NSF attachment protein alpha increases expression ISO Metribolone results in increased expression of NAPA protein CTD PMID:17152098 NCBI chr 1:76,787,036...76,805,869
Ensembl chr 1:76,786,932...76,805,869
JBrowse link
G Nav1 neuron navigator 1 decreases expression ISO Metribolone results in decreased expression of NAV1 mRNA CTD PMID:16751804 NCBI chr13:46,866,972...47,119,368
Ensembl chr13:46,873,689...47,126,449
JBrowse link
G Ncl nucleolin multiple interactions ISO Metribolone promotes the reaction [NDRG1 protein binds to NCL protein] CTD PMID:17220478 NCBI chr 9:86,999,588...87,008,112
Ensembl chr 9:86,998,019...87,008,136
JBrowse link
G Ncoa1 nuclear receptor coactivator 1 multiple interactions ISO [Metribolone binds to and affects the folding of AR protein] promotes the reaction [AR protein modified form binds to NCOA1 protein modified form]; Metribolone inhibits the reaction [NCOA1 protein results in increased activity of AR protein] CTD PMID:11981028 PMID:28751236 NCBI chr 6:27,232,609...27,507,992
Ensembl chr 6:27,232,611...27,475,664
JBrowse link
G Ncoa2 nuclear receptor coactivator 2 multiple interactions ISO [Metribolone binds to and affects the folding of AR protein] promotes the reaction [AR protein modified form binds to NCOA2 protein modified form]; arsenic trioxide inhibits the reaction [Metribolone promotes the reaction [NCOA2 protein binds to KLK3 promoter]]; Metribolone promotes the reaction [NCOA2 protein binds to KLK3 promoter] CTD PMID:19131511 PMID:28751236 NCBI chr 5:5,835,642...6,069,693
Ensembl chr 5:5,835,706...6,067,451
JBrowse link
G Ncoa3 nuclear receptor coactivator 3 multiple interactions ISO [Metribolone binds to and affects the folding of AR protein] affects the reaction [AR protein modified form binds to NCOA3 protein modified form]; Metribolone inhibits the reaction [NCOA3 protein results in increased activity of AR protein] CTD PMID:11981028 PMID:28751236 NCBI chr 3:154,738,566...154,821,395
Ensembl chr 3:154,738,581...154,818,594
JBrowse link
G Ncoa6 nuclear receptor coactivator 6 increases expression
multiple interactions
ISO Metribolone results in increased expression of NCOA6 mRNA
[Metribolone binds to and affects the folding of AR protein] promotes the reaction [AR protein modified form binds to NCOA6 protein modified form]
CTD PMID:17010196 PMID:28751236 NCBI chr 3:143,890,896...143,961,916
Ensembl chr 3:143,890,896...143,952,268
JBrowse link
G Ncor1 nuclear receptor co-repressor 1 multiple interactions ISO [Metribolone binds to and affects the folding of AR protein] affects the reaction [AR protein modified form binds to NCOR1 protein modified form] CTD PMID:28751236 NCBI chr10:46,999,536...47,142,294
Ensembl chr10:46,999,536...47,141,032
JBrowse link
G Ncor2 nuclear receptor co-repressor 2 multiple interactions ISO [Metribolone binds to and affects the folding of AR protein] inhibits the reaction [AR protein modified form binds to NCOR2 protein modified form] CTD PMID:28751236 NCBI chr12:31,466,418...31,628,319
Ensembl chr12:31,466,412...31,628,319
JBrowse link
G Ndrg1 N-myc downstream regulated 1 multiple interactions
increases expression
ISO Metribolone promotes the reaction [NDRG1 protein binds to ACSL3 protein]; Metribolone promotes the reaction [NDRG1 protein binds to ACTB protein]; Metribolone promotes the reaction [NDRG1 protein binds to AP1M2 protein]; Metribolone promotes the reaction [NDRG1 protein binds to AP2M1 protein]; Metribolone promotes the reaction [NDRG1 protein binds to ATP1A1 protein]; Metribolone promotes the reaction [NDRG1 protein binds to CANX protein]; Metribolone promotes the reaction [NDRG1 protein binds to CLTC protein]; Metribolone promotes the reaction [NDRG1 protein binds to CNDP2 protein]; Metribolone promotes the reaction [NDRG1 protein binds to COPB2 protein]; Metribolone promotes the reaction [NDRG1 protein binds to CTNNB1 protein]; Metribolone promotes the reaction [NDRG1 protein binds to DARS1 protein]; Metribolone promotes the reaction [NDRG1 protein binds to DDX1 protein]; Metribolone promotes the reaction [NDRG1 protein binds to DDX5 protein]; Metribolone promotes the reaction [NDRG1 protein binds to DLST protein]; Metribolone promotes the reaction [NDRG1 protein binds to EEF1G protein]; Metribolone promotes the reaction [NDRG1 protein binds to EEF2 protein]; Metribolone promotes the reaction [NDRG1 protein binds to EIF2S3 protein]; Metribolone promotes the reaction [NDRG1 protein binds to EIF3E protein]; Metribolone promotes the reaction [NDRG1 protein binds to EWSR1 protein]; Metribolone promotes the reaction [NDRG1 protein binds to FASN protein]; Metribolone promotes the reaction [NDRG1 protein binds to HNRNPF protein]; Metribolone promotes the reaction [NDRG1 protein binds to HNRNPH1 protein]; Metribolone promotes the reaction [NDRG1 protein binds to HNRNPU protein]; Metribolone promotes the reaction [NDRG1 protein binds to HSD17B4 protein]; Metribolone promotes the reaction [NDRG1 protein binds to HSP90AA1 protein]; Metribolone promotes the reaction [NDRG1 protein binds to HSPA5 protein]; Metribolone promotes the reaction [NDRG1 protein binds to ILF3 protein]; Metribolone promotes the reaction [NDRG1 protein binds to KIF5B protein]; Metribolone promotes the reaction [NDRG1 protein binds to LDHA protein]; Metribolone promotes the reaction [NDRG1 protein binds to MAOA protein]; Metribolone promotes the reaction [NDRG1 protein binds to MME protein]; Metribolone promotes the reaction [NDRG1 protein binds to NCL protein]; Metribolone promotes the reaction [NDRG1 protein binds to NDRG1 protein]; Metribolone promotes the reaction [NDRG1 protein binds to PABPC1 protein]; Metribolone promotes the reaction [NDRG1 protein binds to PKM protein]; Metribolone promotes the reaction [NDRG1 protein binds to PPP2R2A protein]; Metribolone promotes the reaction [NDRG1 protein binds to PSMC2 protein]; Metribolone promotes the reaction [NDRG1 protein binds to PSMD2 protein]; Metribolone promotes the reaction [NDRG1 protein binds to RPL24 protein]; Metribolone promotes the reaction [NDRG1 protein binds to RPL3 protein]; Metribolone promotes the reaction [NDRG1 protein binds to RPL4 protein]; Metribolone promotes the reaction [NDRG1 protein binds to RPN2 protein]; Metribolone promotes the reaction [NDRG1 protein binds to RPS16 protein]; Metribolone promotes the reaction [NDRG1 protein binds to RPS20 protein]; Metribolone promotes the reaction [NDRG1 protein binds to RPS26 protein]; Metribolone promotes the reaction [NDRG1 protein binds to RPS3 protein]; Metribolone promotes the reaction [NDRG1 protein binds to RPS6 protein]; Metribolone promotes the reaction [NDRG1 protein binds to RPS8 protein]; Metribolone promotes the reaction [NDRG1 protein binds to RPS9 protein]; Metribolone promotes the reaction [NDRG1 protein binds to RUVBL2 protein]; Metribolone promotes the reaction [NDRG1 protein binds to SEC23A protein]; Metribolone promotes the reaction [NDRG1 protein binds to SHMT2 protein]; Metribolone promotes the reaction [NDRG1 protein binds to SLC25A6 protein]; Metribolone promotes the reaction [NDRG1 protein binds to TARS1 protein]; Metribolone promotes the reaction [NDRG1 protein binds to TLE3 protein]; Metribolone promotes the reaction [NDRG1 protein binds to UPF1 protein]; Metribolone promotes the reaction [NDRG1 protein binds to VCP protein]; Metribolone promotes the reaction [NDRG1 protein binds to XRCC6 protein]
Metribolone results in increased expression of NDRG1 protein
CTD PMID:17220478 NCBI chr 7:98,684,487...98,725,869
Ensembl chr 7:98,684,487...98,725,880
JBrowse link
G Ndufa3 NADH:ubiquinone oxidoreductase subunit A3 affects splicing ISO Metribolone affects the splicing of NDUFA3 mRNA CTD PMID:17010196 NCBI chr 1:65,597,567...65,600,197
Ensembl chr 1:65,597,578...65,600,235
JBrowse link
G Nelfb negative elongation factor complex member B multiple interactions ISO [Metribolone binds to and affects the folding of AR protein] inhibits the reaction [AR protein modified form binds to NELFB protein modified form] CTD PMID:28751236 NCBI chr 3:8,010,883...8,027,403
Ensembl chr 3:8,010,888...8,027,403
JBrowse link
G Nemf nuclear export mediator factor increases expression ISO Metribolone results in increased expression of NEMF mRNA CTD PMID:17010196 NCBI chr 6:87,791,650...87,835,826
Ensembl chr 6:87,791,656...87,835,841
JBrowse link
G Nfkbib NFKB inhibitor beta multiple interactions ISO [Metribolone binds to and affects the folding of AR protein] inhibits the reaction [AR protein modified form binds to NFKBIB protein modified form] CTD PMID:28751236 NCBI chr 1:84,046,292...84,053,862
Ensembl chr 1:84,046,295...84,053,862
JBrowse link
G Ngly1 N-glycanase 1 increases expression ISO Metribolone results in increased expression of NGLY1 mRNA CTD PMID:16751804 NCBI chr15:9,153,738...9,210,228
Ensembl chr15:9,153,738...9,204,630
JBrowse link
G Nkx3-1 NK3 homeobox 1 multiple interactions
increases expression
decreases expression
ISO bicalutamide inhibits the reaction [Metribolone results in increased expression of NKX3-1 mRNA]; Dapsone analog inhibits the reaction [Metribolone results in increased expression of NKX3-1 mRNA]; Metribolone promotes the reaction [AR protein binds to NKX3-1 enhancer]; Metribolone promotes the reaction [AR protein binds to NKX3-1 promoter]; Metribolone promotes the reaction [KDM3A protein binds to NKX3-1 enhancer]; Metribolone promotes the reaction [UXT protein binds to NKX3-1 promoter]; TP53 protein inhibits the reaction [Metribolone results in increased expression of NKX3-1 mRNA]; UXT protein affects the reaction [Metribolone results in increased expression of NKX3-1 mRNA]
Metribolone results in increased expression of NKX3-1 mRNA; Metribolone results in increased expression of NKX3-1 protein
Metribolone results in decreased expression of NKX3-1 mRNA
CTD PMID:11751618 PMID:12711008 PMID:16603237 PMID:17010675 PMID:17131305 More... NCBI chr15:44,473,851...44,476,443
Ensembl chr15:44,473,851...44,476,441
JBrowse link
G Nln neurolysin increases expression ISO Metribolone results in increased expression of NLN protein CTD PMID:17152098 NCBI chr 2:35,133,634...35,232,927
Ensembl chr 2:35,134,145...35,232,914
JBrowse link
G Nnmt nicotinamide N-methyltransferase increases expression ISO Metribolone results in increased expression of NNMT mRNA CTD PMID:17010675 NCBI chr 8:48,928,663...48,947,734
Ensembl chr 8:48,933,598...48,946,655
JBrowse link
G Nploc4 NPL4 homolog, ubiquitin recognition factor increases expression ISO Metribolone results in increased expression of NPLOC4 protein CTD PMID:17152098 NCBI chr10:105,654,395...105,709,958
Ensembl chr10:105,654,812...105,709,913
JBrowse link
G Nr0b1 nuclear receptor subfamily 0, group B, member 1 multiple interactions ISO [Metribolone binds to and affects the folding of AR protein] promotes the reaction [AR protein modified form binds to NR0B1 protein modified form] CTD PMID:28751236 NCBI chr  X:50,756,886...50,761,014
Ensembl chr  X:50,756,886...50,761,011
JBrowse link
G Nr0b2 nuclear receptor subfamily 0, group B, member 2 multiple interactions ISO [Metribolone binds to and affects the folding of AR protein] affects the reaction [AR protein modified form binds to NR0B2 protein modified form] CTD PMID:28751236 NCBI chr 5:145,779,294...145,782,609
Ensembl chr 5:145,779,294...145,782,609
JBrowse link
G Nr3c2 nuclear receptor subfamily 3, group C, member 2 multiple interactions ISO Metribolone binds to and results in decreased activity of NR3C2 protein; Metribolone inhibits the reaction [Aldosterone results in increased activity of NR3C2 protein] CTD PMID:17105867 NCBI chr19:30,715,634...31,059,885
Ensembl chr19:30,715,648...31,059,885
JBrowse link
G Nr4a1 nuclear receptor subfamily 4, group A, member 1 multiple interactions
increases expression
ISO Dapsone analog inhibits the reaction [Metribolone results in increased expression of NR4A1 mRNA] CTD PMID:21440447 NCBI chr 7:132,368,399...132,389,300
Ensembl chr 7:132,374,840...132,389,297
JBrowse link
G Nrip1 nuclear receptor interacting protein 1 multiple interactions ISO [Metribolone binds to and affects the folding of AR protein] inhibits the reaction [AR protein modified form binds to NRIP1 protein modified form] CTD PMID:28751236 NCBI chr11:14,895,843...14,979,490
Ensembl chr11:14,895,553...14,981,761
JBrowse link
G Nucb2 nucleobindin 2 increases expression ISO Metribolone results in increased expression of NUCB2 mRNA CTD PMID:17010196 NCBI chr 1:170,750,830...170,787,356
Ensembl chr 1:170,750,877...170,787,353
JBrowse link
G Oaz1 ornithine decarboxylase antizyme 1 affects splicing ISO Metribolone affects the splicing of OAZ1 mRNA CTD PMID:17010196 NCBI chr 7:8,883,855...8,886,315
Ensembl chr 7:8,883,851...8,886,310
JBrowse link
G Odc1 ornithine decarboxylase 1 decreases expression EXP Metribolone results in decreased expression of ODC1 mRNA CTD PMID:15519604 NCBI chr 6:40,329,831...40,336,444
Ensembl chr 6:40,329,964...40,336,440
JBrowse link
G Ogdh oxoglutarate dehydrogenase affects splicing ISO Metribolone affects the splicing of OGDH mRNA CTD PMID:17010196 NCBI chr14:81,150,021...81,217,479
Ensembl chr14:81,150,091...81,217,479
JBrowse link
G Orm1 orosomucoid 1 increases expression ISO Metribolone results in increased expression of ORM1 mRNA CTD PMID:16751804 NCBI chr 5:76,766,637...76,776,149
Ensembl chr 5:76,772,941...76,776,154
JBrowse link
G Osr2 odd-skipped related transciption factor 2 decreases expression ISO Metribolone results in decreased expression of OSR2 mRNA CTD PMID:16751804 NCBI chr 7:66,487,841...66,495,003
Ensembl chr 7:66,487,839...66,495,224
JBrowse link
G Pa2g4 proliferation-associated 2G4 multiple interactions ISO PA2G4 protein inhibits the reaction [Cyproterone Acetate promotes the reaction [Metribolone results in increased expression of AR mRNA]]; PA2G4 protein inhibits the reaction [Metribolone results in increased expression of AR mRNA] CTD PMID:15994225 NCBI chr 7:984,795...992,264
Ensembl chr 7:983,971...992,331
JBrowse link
G Pabpc1 poly(A) binding protein, cytoplasmic 1 multiple interactions ISO Metribolone promotes the reaction [NDRG1 protein binds to PABPC1 protein] CTD PMID:17220478 NCBI chr 7:67,777,438...67,789,731
Ensembl chr 7:67,777,381...67,789,744
JBrowse link
G Pak2 p21 (RAC1) activated kinase 2 decreases expression ISO Metribolone results in decreased expression of PAK2 protein CTD PMID:17152098 NCBI chr11:68,707,940...68,768,816
Ensembl chr11:68,707,969...68,768,816
JBrowse link
G Pank4 pantothenate kinase 4 increases expression ISO Metribolone results in increased expression of PANK4 protein CTD PMID:17152098 NCBI chr 5:165,525,340...165,542,139
Ensembl chr 5:165,525,402...165,542,135
JBrowse link
G Park7 Parkinsonism associated deglycase increases expression ISO Metribolone results in increased expression of PARK7 protein CTD PMID:17152098 NCBI chr 5:161,353,718...161,376,993
Ensembl chr 5:161,353,719...161,376,970
JBrowse link
G Pcmt1 protein-L-isoaspartate (D-aspartate) O-methyltransferase 1 affects splicing ISO Metribolone affects the splicing of PCMT1 mRNA CTD PMID:17010196 NCBI chr 1:2,111,756...2,160,354
Ensembl chr 1:2,111,763...2,159,201
JBrowse link
G Pdcd6ip programmed cell death 6 interacting protein decreases expression ISO Metribolone results in decreased expression of PDCD6IP protein CTD PMID:17152098 NCBI chr 8:113,590,998...113,646,795
Ensembl chr 8:113,590,998...113,646,773
JBrowse link
G Pdia3 protein disulfide isomerase family A, member 3 increases expression ISO Metribolone results in increased expression of PDIA3 protein CTD PMID:17152098 NCBI chr 3:108,388,189...108,412,013
Ensembl chr 3:108,388,245...108,413,236
JBrowse link
G Pdia6 protein disulfide isomerase family A, member 6 increases expression ISO Metribolone results in increased expression of PDIA6 protein CTD PMID:17152098 NCBI chr 6:40,062,980...40,080,223
Ensembl chr 6:40,062,926...40,080,613
JBrowse link
G Pds5b PDS5 cohesin associated factor B increases expression ISO Metribolone results in increased expression of PDS5B mRNA CTD PMID:17010196 NCBI chr12:202,481...345,596
Ensembl chr12:255,313...345,596
JBrowse link
G Pdxdc1 pyridoxal-dependent decarboxylase domain containing 1 increases expression ISO Metribolone results in increased expression of PDXDC1 protein CTD PMID:17152098 NCBI chr10:2,025,056...2,113,712
Ensembl chr10:2,025,360...2,113,520
JBrowse link
G Pelp1 proline, glutamate and leucine rich protein 1 multiple interactions ISO [Metribolone binds to and affects the folding of AR protein] inhibits the reaction [AR protein modified form binds to PELP1 protein modified form] CTD PMID:28751236 NCBI chr10:55,094,798...55,111,833
Ensembl chr10:55,094,796...55,111,994
JBrowse link
G Per1 period circadian regulator 1 multiple interactions
increases expression
ISO Dapsone analog inhibits the reaction [Metribolone results in increased expression of PER1 mRNA] CTD PMID:21440447 NCBI chr10:53,800,126...53,814,963
Ensembl chr10:53,805,535...53,814,431
JBrowse link
G Pgm2 phosphoglucomutase 2 increases expression ISO Metribolone results in increased expression of PGM2 protein CTD PMID:17152098 NCBI chr14:44,166,314...44,199,828
Ensembl chr14:44,164,425...44,199,967
JBrowse link
G Pgr progesterone receptor affects binding ISO Metribolone binds to PGR protein CTD PMID:15189034 NCBI chr 8:6,072,673...6,131,552
Ensembl chr 8:6,072,673...6,131,344
JBrowse link
G Phb1 prohibitin 1 decreases expression ISO Metribolone results in decreased expression of PHB1 protein CTD PMID:17152098 NCBI chr10:80,605,268...80,618,043
Ensembl chr10:80,605,251...80,618,042
JBrowse link
G Phgdh phosphoglycerate dehydrogenase decreases expression
increases expression
ISO Metribolone results in decreased expression of PHGDH protein
Metribolone results in increased expression of PHGDH protein
CTD PMID:17152098 NCBI chr 2:185,906,962...185,936,054
Ensembl chr 2:185,906,966...185,935,944
JBrowse link
G Pias1 protein inhibitor of activated STAT, 1 increases expression ISO Metribolone results in increased expression of PIAS1 mRNA CTD PMID:16751804 NCBI chr 8:63,338,150...63,451,670
Ensembl chr 8:63,338,150...63,438,905
JBrowse link
G Pias2 protein inhibitor of activated STAT, 2 multiple interactions ISO [Metribolone binds to and affects the folding of AR protein] inhibits the reaction [AR protein modified form binds to PIAS2 protein modified form] CTD PMID:28751236 NCBI chr18:70,608,034...70,714,295
Ensembl chr18:70,607,665...70,710,033
JBrowse link
G Pip4k2b phosphatidylinositol-5-phosphate 4-kinase type 2 beta decreases expression ISO Metribolone results in decreased expression of PIP4K2B mRNA CTD PMID:17010675 NCBI chr10:82,706,016...82,734,938
Ensembl chr10:82,701,098...82,734,938
JBrowse link
G Pkib cAMP-dependent protein kinase inhibitor beta decreases expression ISO Metribolone results in decreased expression of PKIB mRNA CTD PMID:16751804 NCBI chr20:36,965,172...37,062,190
Ensembl chr20:36,905,340...37,062,187
JBrowse link
G Pkm pyruvate kinase M1/2 multiple interactions ISO Metribolone promotes the reaction [NDRG1 protein binds to PKM protein] CTD PMID:17220478 NCBI chr 8:60,057,629...60,079,600
Ensembl chr 8:60,057,402...60,079,599
JBrowse link
G Plin3 perilipin 3 increases expression ISO Metribolone results in increased expression of PLIN3 protein CTD PMID:17152098 NCBI chr 9:1,111,178...1,123,057
Ensembl chr 9:1,102,366...1,123,147
JBrowse link
G Pmepa1 prostate transmembrane protein, androgen induced 1 affects expression
increases expression
ISO Metribolone affects the expression of PMEPA1 mRNA
Metribolone results in increased expression of PMEPA1 mRNA
CTD PMID:12711008 PMID:17010196 PMID:17010675 NCBI chr 3:162,011,884...162,060,343
Ensembl chr 3:162,012,751...162,060,454
JBrowse link
G Potem POTE ankyrin domain family member M increases expression ISO Metribolone results in increased expression of POTEM mRNA CTD PMID:17010196 NCBI chr16:20,193,646...20,311,924
Ensembl chr16:19,949,230...19,976,541
JBrowse link
G Ppargc1a PPARG coactivator 1 alpha multiple interactions ISO [Metribolone binds to and affects the folding of AR protein] promotes the reaction [AR protein modified form binds to PPARGC1A protein modified form] CTD PMID:28751236 NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656
JBrowse link
G Pphln1 periphilin 1 increases expression ISO Metribolone results in increased expression of PPHLN1 mRNA CTD PMID:17010196 NCBI chr 7:124,538,594...124,629,985
Ensembl chr 7:124,538,627...124,629,985
JBrowse link
G Ppp2r2a protein phosphatase 2, regulatory subunit B, alpha multiple interactions
decreases expression
ISO Metribolone promotes the reaction [NDRG1 protein binds to PPP2R2A protein]
Metribolone results in decreased expression of PPP2R2A protein
CTD PMID:17152098 PMID:17220478 NCBI chr15:41,204,659...41,263,924
Ensembl chr15:41,204,200...41,263,924
JBrowse link
G Pprc1 PPARG related coactivator 1 multiple interactions ISO [Metribolone binds to and affects the folding of AR protein] inhibits the reaction [AR protein modified form binds to PPRC1 protein modified form] CTD PMID:28751236 NCBI chr 1:244,901,985...244,918,587
Ensembl chr 1:244,902,179...244,918,587
JBrowse link
G Pramex1 PRAME like, X-linked 1 multiple interactions ISO [Metribolone binds to and affects the folding of AR protein] inhibits the reaction [AR protein modified form binds to PRAME protein modified form] CTD PMID:28751236 NCBI chr  X:98,567,994...98,574,654
Ensembl chr  X:98,569,415...98,572,096
JBrowse link
G Prdm2 PR/SET domain 2 multiple interactions ISO [Metribolone binds to and affects the folding of AR protein] promotes the reaction [AR protein modified form binds to PRDM2 protein modified form] CTD PMID:28751236 NCBI chr 5:155,421,066...155,531,884
Ensembl chr 5:155,422,134...155,531,825
JBrowse link
G Prdx1 peroxiredoxin 1 affects splicing ISO Metribolone affects the splicing of PRDX1 mRNA CTD PMID:17010196 NCBI chr 5:130,147,258...130,162,856
Ensembl chr 5:130,147,204...130,162,856
JBrowse link
G Prdx3 peroxiredoxin 3 affects localization ISO Metribolone affects the localization of PRDX3 protein CTD PMID:17440980 NCBI chr 1:260,001,642...260,014,064
Ensembl chr 1:260,001,637...260,014,111
JBrowse link
G Prdx6 peroxiredoxin 6 increases expression ISO Metribolone results in increased expression of PRDX6 protein CTD PMID:17152098 NCBI chr13:73,528,746...73,539,295
Ensembl chr13:73,528,210...73,539,355
JBrowse link
G Prkacb protein kinase cAMP-activated catalytic subunit beta affects expression ISO Metribolone affects the expression of PRKACB mRNA alternative form; Metribolone affects the expression of PRKACB protein alternative form CTD PMID:16949795 NCBI chr 2:235,636,878...235,726,928
Ensembl chr 2:235,636,885...235,726,198
JBrowse link
G Prkca protein kinase C, alpha multiple interactions ISO Metribolone promotes the reaction [EZR protein binds to PRKCA protein]; PRKCA protein affects the reaction [Metribolone results in increased phosphorylation of EZR protein] CTD PMID:16873375 NCBI chr10:92,889,390...93,288,013
Ensembl chr10:92,894,012...93,288,012
JBrowse link
G Prps2 phosphoribosyl pyrophosphate synthetase 2 decreases expression ISO Metribolone results in decreased expression of PRPS2 protein CTD PMID:17152098 NCBI chr  X:26,975,915...27,013,184
Ensembl chr  X:26,976,061...27,013,181
JBrowse link
G Psmc1 proteasome 26S subunit, ATPase 1 increases expression ISO Metribolone results in increased expression of PSMC1 protein CTD PMID:17152098 NCBI chr 6:119,392,833...119,405,233
Ensembl chr 6:119,392,855...119,410,123
JBrowse link
G Psmc2 proteasome 26S subunit, ATPase 2 multiple interactions ISO Metribolone promotes the reaction [NDRG1 protein binds to PSMC2 protein] CTD PMID:17220478 NCBI chr 4:13,255,850...13,270,160
Ensembl chr 4:13,255,856...13,270,185
JBrowse link
G Psmc3 proteasome 26S subunit, ATPase 3 increases expression ISO Metribolone results in increased expression of PSMC3 protein CTD PMID:17152098 NCBI chr 3:77,031,825...77,037,207
Ensembl chr 3:77,031,825...77,043,358
JBrowse link
G Psmd2 proteasome 26S subunit ubiquitin receptor, non-ATPase 2 multiple interactions
increases expression
ISO Metribolone promotes the reaction [NDRG1 protein binds to PSMD2 protein]
Metribolone results in increased expression of PSMD2 protein
CTD PMID:17152098 PMID:17220478 NCBI chr11:80,248,364...80,258,991
Ensembl chr11:80,248,364...80,259,043
JBrowse link
G Psmd6 proteasome 26S subunit, non-ATPase 6 increases expression ISO Metribolone results in increased expression of PSMD6 mRNA CTD PMID:17010196 NCBI chr15:11,102,174...11,112,180
Ensembl chr15:11,102,180...11,205,620
JBrowse link
G Psme3 proteasome activator subunit 3 decreases expression ISO Metribolone results in decreased expression of PSME3 protein CTD PMID:17152098 NCBI chr10:86,257,672...86,265,458
Ensembl chr10:86,257,668...86,333,804
JBrowse link
G Pten phosphatase and tensin homolog decreases response to substance ISO PTEN protein results in decreased susceptibility to Metribolone CTD PMID:16637073 NCBI chr 1:230,630,443...230,697,070
Ensembl chr 1:230,630,338...230,696,838
JBrowse link
G Ptger4 prostaglandin E receptor 4 increases expression ISO Metribolone results in increased expression of PTGER4 mRNA CTD PMID:17010675 NCBI chr 2:54,330,563...54,347,451
Ensembl chr 2:54,335,424...54,346,670
JBrowse link
G Pthlh parathyroid hormone-like hormone decreases expression ISO Metribolone results in decreased expression of PTHLH protein CTD PMID:17676588 NCBI chr 4:180,188,792...180,199,847
Ensembl chr 4:180,188,792...180,199,847
JBrowse link
G Ptov1 PTOV1, extended AT-hook containing adaptor protein increases expression ISO Metribolone results in increased expression of PTOV1 mRNA CTD PMID:17010196 NCBI chr 1:95,347,065...95,354,514
Ensembl chr 1:95,347,068...95,353,613
JBrowse link
G Ptprm protein tyrosine phosphatase, receptor type, M increases expression ISO Metribolone results in increased expression of PTPRM mRNA CTD PMID:16751804 NCBI chr 9:106,639,573...107,343,698
Ensembl chr 9:106,639,573...107,343,698
JBrowse link
G Rbl2 RB transcriptional corepressor like 2 multiple interactions ISO [Metribolone binds to and affects the folding of AR protein] promotes the reaction [AR protein modified form binds to RBL2 protein modified form] CTD PMID:28751236 NCBI chr19:15,876,852...15,923,632
Ensembl chr19:15,876,853...15,923,572
JBrowse link
G Rbm6 RNA binding motif protein 6 increases expression ISO Metribolone results in increased expression of RBM6 mRNA CTD PMID:17010196 NCBI chr 8:108,452,687...108,552,783
Ensembl chr 8:108,452,687...108,552,771
JBrowse link
G Rdh11 retinol dehydrogenase 11 increases expression ISO Metribolone results in increased expression of RDH11 mRNA CTD PMID:17010196 NCBI chr 6:97,979,377...97,995,252
Ensembl chr 6:97,979,378...97,995,252
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO [Metribolone binds to and affects the folding of AR protein] promotes the reaction [AR protein modified form binds to RELA protein modified form] CTD PMID:28751236 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Rhou ras homolog family member U increases expression ISO Metribolone results in increased expression of RHOU mRNA CTD PMID:16751804 NCBI chr19:51,641,476...51,651,249
Ensembl chr19:51,641,227...51,650,552
JBrowse link
G Rmc1 regulator of MON1-CCZ1 increases expression ISO Metribolone results in increased expression of RMC1 mRNA CTD PMID:17010196 NCBI chr18:3,359,848...3,379,764
Ensembl chr18:3,359,832...3,380,795
JBrowse link
G Rmdn1 regulator of microtubule dynamics 1 affects localization ISO Metribolone affects the localization of RMDN1 protein CTD PMID:17440980 NCBI chr 5:33,070,267...33,093,922
Ensembl chr 5:33,070,265...33,127,328
JBrowse link
G Rpl11 ribosomal protein L11 affects splicing ISO Metribolone affects the splicing of RPL11 mRNA CTD PMID:17010196 NCBI chr 5:148,274,060...148,277,708
Ensembl chr 5:148,274,069...148,277,599
JBrowse link
G Rpl24 ribosomal protein L24 multiple interactions ISO Metribolone promotes the reaction [NDRG1 protein binds to RPL24 protein] CTD PMID:17220478 NCBI chr11:44,653,937...44,659,346
Ensembl chr11:44,653,937...44,659,370
JBrowse link
G Rpl3 ribosomal protein L3 multiple interactions ISO Metribolone promotes the reaction [NDRG1 protein binds to RPL3 protein] CTD PMID:17220478 NCBI chr 7:111,622,255...111,627,640
Ensembl chr 7:111,621,610...111,636,468
JBrowse link
G Rpl4 ribosomal protein L4 multiple interactions ISO Metribolone promotes the reaction [NDRG1 protein binds to RPL4 protein] CTD PMID:17220478 NCBI chr 8:64,671,177...64,676,301
Ensembl chr 8:64,671,160...64,676,306
JBrowse link
G Rpn2 ribophorin II multiple interactions ISO Metribolone promotes the reaction [NDRG1 protein binds to RPN2 protein] CTD PMID:17220478 NCBI chr 3:145,941,787...145,989,271
Ensembl chr 3:145,941,839...145,989,543
JBrowse link
G Rps16 ribosomal protein S16 multiple interactions ISO Metribolone promotes the reaction [NDRG1 protein binds to RPS16 protein] CTD PMID:17220478 NCBI chr 1:83,643,066...83,646,056
Ensembl chr 1:83,643,130...83,646,206
JBrowse link
G Rps20 ribosomal protein S20 multiple interactions ISO Metribolone promotes the reaction [NDRG1 protein binds to RPS20 protein] CTD PMID:17220478 NCBI chr 5:16,819,095...16,820,476
Ensembl chr 5:16,819,304...16,820,475
Ensembl chr 9:16,819,304...16,820,475
Ensembl chr 3:16,819,304...16,820,475
JBrowse link
G Rps26 ribosomal protein S26 multiple interactions ISO Metribolone promotes the reaction [NDRG1 protein binds to RPS26 protein] CTD PMID:17220478 NCBI chr 7:1,057,332...1,058,882 JBrowse link
G Rps27l ribosomal protein S27-like affects splicing ISO Metribolone affects the splicing of RPS27L mRNA CTD PMID:17010196 NCBI chr 8:67,562,483...67,567,418
Ensembl chr 8:67,562,483...67,567,418
JBrowse link
G Rps3 ribosomal protein S3 multiple interactions ISO Metribolone promotes the reaction [NDRG1 protein binds to RPS3 protein] CTD PMID:17220478 NCBI chr 1:153,778,363...153,783,663
Ensembl chr 1:153,777,472...153,783,680
JBrowse link
G Rps6 ribosomal protein S6 multiple interactions ISO Metribolone promotes the reaction [NDRG1 protein binds to RPS6 protein] CTD PMID:17220478 NCBI chr 5:101,371,716...101,374,576
Ensembl chr 5:101,371,136...101,374,602
Ensembl chr 5:101,371,136...101,374,602
JBrowse link
G Rps8 ribosomal protein S8 multiple interactions ISO Metribolone promotes the reaction [NDRG1 protein binds to RPS8 protein] CTD PMID:17220478 NCBI chr 5:130,630,362...130,632,932
Ensembl chr 5:130,629,716...130,633,268
JBrowse link
G Rps9 ribosomal protein S9 multiple interactions ISO Metribolone promotes the reaction [NDRG1 protein binds to RPS9 protein] CTD PMID:17220478 NCBI chr 1:65,511,723...65,515,076
Ensembl chr 1:65,511,723...65,515,123
JBrowse link
G Rpsa ribosomal protein SA increases expression ISO Metribolone results in increased expression of RPSA protein CTD PMID:17152098 NCBI chr 8:119,851,225...119,855,103
Ensembl chr 8:119,851,225...119,855,247
JBrowse link
G Rrp12 ribosomal RNA processing 12 increases expression ISO Metribolone results in increased expression of RRP12 mRNA CTD PMID:16751804 NCBI chr 1:240,672,378...240,705,992
Ensembl chr 1:240,672,382...240,706,018
JBrowse link
G Rrp7a ribosomal RNA processing 7 homolog A increases expression ISO Metribolone results in increased expression of RRP7A mRNA CTD PMID:17010196 NCBI chr 7:114,262,929...114,272,817
Ensembl chr 7:114,256,472...114,272,817
JBrowse link
G Ruvbl2 RuvB-like AAA ATPase 2 multiple interactions ISO Metribolone promotes the reaction [NDRG1 protein binds to RUVBL2 protein] CTD PMID:17220478 NCBI chr 1:95,902,014...95,915,247
Ensembl chr 1:95,901,701...95,915,342
JBrowse link
G Scp2 sterol carrier protein 2 affects localization ISO Metribolone affects the localization of SCP2 protein CTD PMID:17440980 NCBI chr 5:122,806,949...122,881,259
Ensembl chr 5:122,776,549...122,881,287
JBrowse link
G Sdccag8 SHH signaling and ciliogenesis regulator SDCCAG8 increases expression ISO Metribolone results in increased expression of SDCCAG8 mRNA CTD PMID:17010196 NCBI chr13:88,754,521...88,979,363
Ensembl chr13:88,754,626...89,097,111
JBrowse link
G Sec23a Sec23 homolog A, COPII coat complex component multiple interactions ISO Metribolone promotes the reaction [NDRG1 protein binds to SEC23A protein] CTD PMID:17220478 NCBI chr 6:76,658,793...76,706,125
Ensembl chr 6:76,658,427...76,706,035
JBrowse link
G Selenbp1 selenium binding protein 1 decreases expression ISO Metribolone results in decreased expression of SELENBP1 protein CTD PMID:17152098 NCBI chr 2:182,494,004...182,504,594
Ensembl chr 2:182,493,978...182,504,594
JBrowse link
G Selenop selenoprotein P increases expression
multiple interactions
ISO Metribolone results in increased expression of SELENOP mRNA
resveratrol inhibits the reaction [Metribolone results in increased expression of SELENOP mRNA]
CTD PMID:17131305 PMID:18586690 NCBI chr 2:52,498,123...52,508,409
Ensembl chr 2:52,498,339...52,508,852
JBrowse link
G Septin1 septin 1 increases expression ISO Metribolone results in increased expression of SEPTIN1 mRNA CTD PMID:17010196 NCBI chr 1:181,832,700...181,836,566
Ensembl chr 1:181,832,701...181,836,566
JBrowse link
G Septin2 septin 2 increases expression ISO Metribolone results in increased expression of SEPTIN2 protein CTD PMID:17152098 NCBI chr 9:94,018,141...94,051,386
Ensembl chr 9:94,018,208...94,051,386
JBrowse link
G Serpinb5 serpin family B member 5 decreases expression ISO Metribolone results in decreased expression of SERPINB5 protein CTD PMID:17152098 NCBI chr13:22,985,557...23,005,756
Ensembl chr13:22,985,557...23,005,756
JBrowse link
G Serpine1 serpin family E member 1 increases secretion ISO Metribolone results in increased secretion of SERPINE1 protein CTD PMID:20711410 NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657
JBrowse link
G Sesn1 sestrin 1 multiple interactions
decreases expression
ISO AR protein affects the reaction [Metribolone results in decreased expression of SESN1 protein]
Metribolone results in decreased expression of SESN1 mRNA; Metribolone results in decreased expression of SESN1 protein
CTD PMID:16751804 NCBI chr20:45,294,876...45,387,698
Ensembl chr20:45,294,871...45,387,697
JBrowse link
G Sfxn4 sideroflexin 4 increases expression ISO Metribolone results in increased expression of SFXN4 mRNA CTD PMID:17010196 NCBI chr 1:259,976,480...259,998,778
Ensembl chr 1:259,976,481...259,998,754
JBrowse link
G Sh3glb2 SH3 domain-containing GRB2-like endophilin B2 increases expression ISO Metribolone results in increased expression of SH3GLB2 mRNA CTD PMID:17010196 NCBI chr 3:13,616,936...13,631,785
Ensembl chr 3:13,616,938...13,631,757
JBrowse link
G Shmt2 serine hydroxymethyltransferase 2 multiple interactions ISO Metribolone promotes the reaction [NDRG1 protein binds to SHMT2 protein] CTD PMID:17220478 NCBI chr 7:63,358,961...63,364,293
Ensembl chr 7:63,358,961...63,364,236
JBrowse link
G Sil1 SIL1 nucleotide exchange factor increases expression ISO Metribolone results in increased expression of SIL1 protein CTD PMID:17152098 NCBI chr18:26,872,423...27,104,365
Ensembl chr18:26,872,429...27,104,332
JBrowse link
G Slc25a5-ps11 solute carrier family 25 member 5, pseudogene 11 multiple interactions ISO Metribolone promotes the reaction [NDRG1 protein binds to SLC25A6 protein] CTD PMID:17220478 NCBI chr18:68,571,222...68,572,461
Ensembl chr18:68,571,300...68,572,199
JBrowse link
G Slc30a3 solute carrier family 30 member 3 increases expression ISO Metribolone results in increased expression of SLC30A3 mRNA CTD PMID:14662799 NCBI chr 6:25,264,310...25,284,720
Ensembl chr 6:25,275,528...25,284,720
JBrowse link
G Slc30a7 solute carrier family 30 member 7 increases expression ISO Metribolone results in increased expression of SLC30A7 mRNA CTD PMID:16751804 NCBI chr 2:203,855,484...203,922,155
Ensembl chr 2:203,859,175...203,922,132
JBrowse link
G Slc30a9 solute carrier family 30 member 9 multiple interactions ISO [Metribolone binds to and affects the folding of AR protein] promotes the reaction [AR protein modified form binds to SLC30A9 protein modified form] CTD PMID:28751236 NCBI chr14:40,816,284...40,870,992
Ensembl chr14:40,816,290...40,870,929
JBrowse link
G Slc31a1 solute carrier family 31 member 1 multiple interactions
increases expression
ISO [Metribolone results in increased expression of SLC31A1 protein] which results in increased import of Copper; AR protein promotes the reaction [Metribolone results in increased expression of SLC31A1 mRNA]; AR protein promotes the reaction [Metribolone results in increased expression of SLC31A1 protein]
Metribolone results in increased expression of SLC31A1 mRNA; Metribolone results in increased expression of SLC31A1 protein
CTD PMID:25320179 NCBI chr 5:75,814,744...75,844,241
Ensembl chr 5:75,814,743...75,844,228
JBrowse link
G Slc35c2 solute carrier family 35 member C2 increases expression ISO Metribolone results in increased expression of SLC35C2 mRNA CTD PMID:17010196 NCBI chr 3:154,012,262...154,023,549
Ensembl chr 3:154,012,416...154,023,488
JBrowse link
G Slc43a1 solute carrier family 43 member 1 increases expression ISO Metribolone results in increased expression of SLC43A1 mRNA CTD PMID:17010196 NCBI chr 3:69,920,586...69,946,768
Ensembl chr 3:69,920,649...69,946,768
JBrowse link
G Slc45a3 solute carrier family 45, member 3 increases expression ISO Metribolone results in increased expression of SLC45A3 mRNA CTD PMID:17010196 NCBI chr13:43,407,293...43,427,588
Ensembl chr13:43,407,293...43,427,588
JBrowse link
G Sms spermine synthase increases expression ISO Metribolone results in increased expression of SMS protein CTD PMID:17152098 NCBI chr  X:37,516,949...37,572,657
Ensembl chr  X:37,516,931...37,570,822
JBrowse link
G Sncg synuclein, gamma increases expression ISO Metribolone results in increased expression of SNCG mRNA CTD PMID:17010196 NCBI chr16:9,700,513...9,705,751
Ensembl chr16:9,700,514...9,705,368
JBrowse link
G Socs2 suppressor of cytokine signaling 2 increases expression ISO Metribolone results in increased expression of SOCS2 mRNA CTD PMID:16751804 NCBI chr 7:30,006,360...30,045,161
Ensembl chr 7:30,008,578...30,043,548
JBrowse link
G Spcs3 signal peptidase complex subunit 3 increases expression ISO Metribolone results in increased expression of SPCS3 mRNA CTD PMID:16751804 NCBI chr16:37,305,358...37,310,792
Ensembl chr16:37,305,305...37,331,746
JBrowse link
G Spin1 spindlin 1 increases expression ISO Metribolone results in increased expression of SPIN1 mRNA CTD PMID:17010196 NCBI chr17:14,055,685...14,105,366
Ensembl chr17:14,055,689...14,105,411
JBrowse link
G Spon2 spondin 2 increases expression ISO Metribolone results in increased expression of SPON2 mRNA CTD PMID:17010196 NCBI chr14:77,505,695...77,518,001
Ensembl chr14:77,511,901...77,517,996
JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase multiple interactions EXP Metribolone results in increased phosphorylation of and results in increased activity of SRC protein CTD PMID:17272394 NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476
JBrowse link
G Stard10 StAR-related lipid transfer domain containing 10 increases expression ISO Metribolone results in increased expression of STARD10 mRNA CTD PMID:17010196 NCBI chr 1:155,722,637...155,748,007
Ensembl chr 1:155,718,389...155,747,094
JBrowse link
G Steap1 STEAP family member 1 increases expression ISO Metribolone results in increased expression of STEAP1 mRNA CTD PMID:17010196 NCBI chr 4:28,276,972...28,287,484
Ensembl chr 4:28,276,909...28,287,479
JBrowse link
G Steap2 STEAP2 metalloreductase increases expression ISO Metribolone results in increased expression of STEAP2 mRNA CTD PMID:17010196 NCBI chr 4:28,347,769...28,368,177
Ensembl chr 4:28,348,362...28,375,791
JBrowse link
G Steap4 STEAP4 metalloreductase multiple interactions
increases expression
ISO AR protein promotes the reaction [Metribolone results in increased expression of STEAP4 mRNA] CTD PMID:25320179 NCBI chr 4:26,077,182...26,099,859
Ensembl chr 4:26,054,671...26,099,859
JBrowse link
G Stip1 stress-induced phosphoprotein 1 affects localization
increases expression
ISO Metribolone affects the localization of STIP1 protein
Metribolone results in increased expression of STIP1 protein
CTD PMID:17152098 PMID:17440980 NCBI chr 1:204,209,433...204,228,452
Ensembl chr 1:204,178,932...204,228,476
JBrowse link
G Stk39 serine threonine kinase 39 increases expression
multiple interactions
ISO Metribolone results in increased expression of STK39 mRNA
resveratrol inhibits the reaction [Metribolone results in increased expression of STK39 mRNA]
CTD PMID:17131305 PMID:18586690 NCBI chr 3:52,913,583...53,179,060
Ensembl chr 3:52,913,585...53,179,060
JBrowse link
G Sucla2 succinate-CoA ligase ADP-forming subunit beta increases expression ISO Metribolone results in increased expression of SUCLA2 protein CTD PMID:17152098 NCBI chr15:48,752,356...48,805,495
Ensembl chr15:48,752,312...48,805,138
JBrowse link
G Tacc1 transforming, acidic coiled-coil containing protein 1 increases expression ISO Metribolone results in increased expression of TACC1 mRNA CTD PMID:17010196 NCBI chr16:66,812,232...66,895,736
Ensembl chr16:66,812,295...66,895,733
JBrowse link
G Taldo1 transaldolase 1 decreases expression ISO Metribolone results in decreased expression of TALDO1 protein CTD PMID:17152098 NCBI chr 1:196,493,634...196,503,965
Ensembl chr 1:196,493,589...196,503,974
JBrowse link
G Tardbp TAR DNA binding protein decreases expression ISO Metribolone results in decreased expression of TARDBP protein CTD PMID:17152098 NCBI chr 5:159,050,518...159,062,218
Ensembl chr 5:159,051,799...159,062,055
JBrowse link
G Tars1 threonyl-tRNA synthetase 1 multiple interactions ISO Metribolone promotes the reaction [NDRG1 protein binds to TARS1 protein] CTD PMID:17220478 NCBI chr 2:60,368,893...60,387,715
Ensembl chr 2:60,367,796...60,387,717
JBrowse link
G Tbcc tubulin folding cofactor C increases expression ISO Metribolone results in increased expression of TBCC protein CTD PMID:17152098 NCBI chr 9:14,098,855...14,100,043
Ensembl chr 9:14,098,868...14,100,042
JBrowse link
G Tert telomerase reverse transcriptase increases activity
increases expression
multiple interactions
ISO Metribolone results in increased activity of TERT protein
Metribolone results in increased expression of TERT mRNA
letrozole inhibits the reaction [Metribolone results in increased activity of TERT protein]; Metribolone inhibits the reaction [Estradiol results in increased activity of TERT protein]; Tamoxifen inhibits the reaction [Metribolone results in increased activity of TERT protein]
CTD PMID:19561322 NCBI chr 1:29,637,213...29,659,561
Ensembl chr 1:29,637,506...29,659,561
JBrowse link
G Tgfb1i1 transforming growth factor beta 1 induced transcript 1 multiple interactions ISO [Metribolone binds to and affects the folding of AR protein] inhibits the reaction [AR protein modified form binds to TGFB1I1 protein modified form] CTD PMID:28751236 NCBI chr 1:182,828,553...182,835,465
Ensembl chr 1:182,828,544...182,837,080
JBrowse link
G Tle3 TLE family member 3, transcriptional corepressor multiple interactions ISO Metribolone promotes the reaction [NDRG1 protein binds to TLE3 protein] CTD PMID:17220478 NCBI chr 8:61,857,791...61,903,505
Ensembl chr 8:61,858,200...61,903,493
JBrowse link
G Tmem50a transmembrane protein 50A increases expression ISO Metribolone results in increased expression of TMEM50A mRNA CTD PMID:16751804 NCBI chr 5:147,123,670...147,138,859
Ensembl chr 5:147,123,688...147,138,849
JBrowse link
G Tnk1 tyrosine kinase, non-receptor, 1 decreases expression ISO Metribolone results in decreased expression of TNK1 mRNA CTD PMID:17010675 NCBI chr10:54,571,396...54,580,547
Ensembl chr10:54,571,117...54,579,940
JBrowse link
G Tp53 tumor protein p53 multiple interactions ISO [Curcumin co-treated with Metribolone] results in increased phosphorylation of TP53 protein; TP53 protein inhibits the reaction [Metribolone results in increased expression of NKX3-1 mRNA] CTD PMID:17202838 PMID:21134073 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Tpx2 TPX2, microtubule nucleation factor increases expression ISO Metribolone results in increased expression of TPX2 mRNA CTD PMID:17010196 NCBI chr 3:141,318,428...141,360,684
Ensembl chr 3:141,318,455...141,360,468
JBrowse link
G Trerf1 transcriptional regulating factor 1 multiple interactions ISO [Metribolone binds to and affects the folding of AR protein] affects the reaction [AR protein modified form binds to TRERF1 protein modified form] CTD PMID:28751236 NCBI chr 9:13,631,619...13,858,326
Ensembl chr 9:13,634,126...13,857,029
JBrowse link
G Trim24 tripartite motif-containing 24 multiple interactions ISO [Metribolone binds to and affects the folding of AR protein] inhibits the reaction [AR protein modified form binds to TRIM24 protein modified form] CTD PMID:28751236 NCBI chr 4:66,567,342...66,692,029
Ensembl chr 4:66,566,686...66,717,241
JBrowse link
G Trim28 tripartite motif-containing 28 decreases expression ISO Metribolone results in decreased expression of TRIM28 protein CTD PMID:17152098 NCBI chr 1:73,652,441...73,659,388
Ensembl chr 1:73,652,709...73,659,380
JBrowse link
G Trps1 transcriptional repressor GATA binding 1 decreases expression ISO Metribolone results in decreased expression of TRPS1 mRNA CTD PMID:19759027 NCBI chr 7:81,916,668...82,142,733
Ensembl chr 7:81,921,601...82,141,905
JBrowse link
G Trrap transformation/transcription domain-associated protein multiple interactions ISO [Metribolone binds to and affects the folding of AR protein] inhibits the reaction [AR protein modified form binds to TRRAP protein modified form] CTD PMID:28751236 NCBI chr12:9,738,006...9,827,708
Ensembl chr12:9,738,006...9,827,674
JBrowse link
G Tshz1 teashirt zinc finger homeobox 1 increases expression ISO Metribolone results in increased expression of TSHZ1 mRNA CTD PMID:17010196 NCBI chr18:77,376,399...77,452,815
Ensembl chr18:77,377,394...77,453,509
JBrowse link
G Tubb5 tubulin, beta 5 class I decreases expression ISO Metribolone results in decreased expression of TUBB protein CTD PMID:17152098 NCBI chr20:2,912,779...2,916,928
Ensembl chr20:2,912,778...2,916,940
JBrowse link
G Txnrd1 thioredoxin reductase 1 decreases expression ISO Metribolone results in decreased expression of TXNRD1 protein CTD PMID:17152098 NCBI chr 7:20,830,042...20,914,990
Ensembl chr 7:20,830,045...20,907,863
JBrowse link
G Uap1 UDP-N-acetylglucosamine pyrophosphorylase 1 increases expression ISO Metribolone results in increased expression of UAP1 protein CTD PMID:17152098 NCBI chr13:82,342,946...82,377,558
Ensembl chr13:82,342,946...82,377,469
JBrowse link
G Uba6 ubiquitin-like modifier activating enzyme 6 increases expression ISO Metribolone results in increased expression of UBA6 protein CTD PMID:17152098 NCBI chr14:21,884,039...21,947,857
Ensembl chr14:21,884,039...21,947,857
JBrowse link
G Ube2j1 ubiquitin-conjugating enzyme E2, J1 increases expression ISO Metribolone results in increased expression of UBE2J1 mRNA CTD PMID:16751804 NCBI chr 5:47,422,476...47,441,476
Ensembl chr 5:47,422,587...47,441,461
JBrowse link
G Ubl5 ubiquitin-like 5 affects splicing ISO Metribolone affects the splicing of UBL5 mRNA CTD PMID:17010196 NCBI chr 8:19,181,504...19,185,224
Ensembl chr 8:19,181,615...19,185,217
JBrowse link
G Ufd1 ubiquitin recognition factor in ER associated degradation 1 decreases expression ISO Metribolone results in decreased expression of UFD1 protein CTD PMID:17152098 NCBI chr11:82,161,618...82,185,107
Ensembl chr11:82,161,619...82,185,087
JBrowse link
G Upf1 UPF1, RNA helicase and ATPase multiple interactions ISO Metribolone promotes the reaction [NDRG1 protein binds to UPF1 protein] CTD PMID:17220478 NCBI chr16:19,076,594...19,097,365
Ensembl chr16:19,076,322...19,096,568
JBrowse link
G Uqcc2 ubiquinol-cytochrome c reductase complex assembly factor 2 increases expression ISO Metribolone results in increased expression of UQCC2 mRNA CTD PMID:17010196 NCBI chr20:5,202,837...5,214,541
Ensembl chr20:5,202,837...5,214,164
JBrowse link
G Usp5 ubiquitin specific peptidase 5 affects localization ISO Metribolone affects the localization of USP5 protein CTD PMID:17440980 NCBI chr 4:157,619,663...157,634,681
Ensembl chr 4:157,619,643...157,634,711
JBrowse link
G Uxt ubiquitously-expressed, prefoldin-like chaperone multiple interactions
affects response to substance
ISO Metribolone promotes the reaction [UXT protein binds to ATR promoter]; Metribolone promotes the reaction [UXT protein binds to GSTE1 promoter]; Metribolone promotes the reaction [UXT protein binds to KLK3 promoter]; Metribolone promotes the reaction [UXT protein binds to NKX3-1 promoter]; UXT protein affects the reaction [Metribolone results in increased expression of BRIP1 mRNA]; UXT protein affects the reaction [Metribolone results in increased expression of KLK3 mRNA]; UXT protein affects the reaction [Metribolone results in increased expression of NKX3-1 mRNA]
UXT protein affects the susceptibility to Metribolone
CTD PMID:19318562 NCBI chr  X:1,126,110...1,138,670
Ensembl chr  X:1,126,162...1,138,663
JBrowse link
G Vcl vinculin increases expression ISO Metribolone results in increased expression of VCL protein CTD PMID:17152098 NCBI chr15:3,265,776...3,355,586
Ensembl chr15:3,265,815...3,355,606
JBrowse link
G Vcp valosin-containing protein multiple interactions
increases expression
ISO Metribolone promotes the reaction [NDRG1 protein binds to VCP protein]
Metribolone results in increased expression of VCP protein
CTD PMID:17152098 PMID:17220478 NCBI chr 5:57,210,167...57,229,571
Ensembl chr 5:57,210,168...57,229,571
JBrowse link
G Vta1 vesicle trafficking 1 decreases expression ISO Metribolone results in decreased expression of VTA1 protein CTD PMID:17152098 NCBI chr 1:9,032,861...9,080,635
Ensembl chr 1:9,032,335...9,080,635
JBrowse link
G Wars1 tryptophanyl-tRNA synthetase 1 increases expression ISO Metribolone results in increased expression of WARS1 protein CTD PMID:17152098 NCBI chr 6:127,776,088...127,807,273
Ensembl chr 6:127,776,090...127,807,269
JBrowse link
G Xpnpep1 X-prolyl aminopeptidase 1 increases expression ISO Metribolone results in increased expression of XPNPEP1 protein CTD PMID:17152098 NCBI chr 1:252,001,366...252,052,077
Ensembl chr 1:252,001,367...252,051,479
JBrowse link
G Xrcc5 X-ray repair cross complementing 5 decreases expression ISO Metribolone results in decreased expression of XRCC5 protein CTD PMID:17152098 NCBI chr 9:73,955,216...74,044,020
Ensembl chr 9:73,955,216...74,044,018
JBrowse link
G Xrcc6 X-ray repair cross complementing 6 multiple interactions ISO Metribolone promotes the reaction [NDRG1 protein binds to XRCC6 protein] CTD PMID:17220478 NCBI chr 7:113,542,992...113,563,762
Ensembl chr 7:113,543,057...113,563,762
JBrowse link
G Xrn1 5'-3' exoribonuclease 1 increases expression
multiple interactions
ISO Metribolone results in increased expression of XRN1 protein
MIR204 mRNA inhibits the reaction [Metribolone results in increased expression of XRN1 protein]
CTD PMID:25797256 NCBI chr 8:96,527,871...96,637,385
Ensembl chr 8:96,528,195...96,632,739
JBrowse link
G Ythdf1 YTH N6-methyladenosine RNA binding protein F1 increases expression ISO Metribolone results in increased expression of YTHDF1 mRNA CTD PMID:17010196 NCBI chr 3:168,024,660...168,040,172
Ensembl chr 3:168,024,663...168,040,172
JBrowse link
G Zbtb10 zinc finger and BTB domain containing 10 increases expression ISO Metribolone results in increased expression of ZBTB10 mRNA CTD PMID:16751804 PMID:17010675 NCBI chr 2:92,475,254...92,509,892
Ensembl chr 2:92,479,014...92,512,515
JBrowse link
G Zdhhc2 zinc finger DHHC-type palmitoyltransferase 2 increases expression ISO Metribolone results in increased expression of ZDHHC2 mRNA CTD PMID:17010196 NCBI chr16:51,808,465...51,878,060
Ensembl chr16:51,808,468...51,878,060
JBrowse link
G Znhit3 zinc finger, HIT-type containing 3 multiple interactions ISO [Metribolone binds to and affects the folding of AR protein] inhibits the reaction [AR protein modified form binds to ZNHIT3 protein modified form] CTD PMID:28751236 NCBI chr10:69,775,885...69,790,471
Ensembl chr10:69,748,789...69,790,475
Ensembl chr10:69,748,789...69,790,475
JBrowse link
boldenone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gpx5 glutathione peroxidase 5 increases expression ISO boldenone results in increased expression of GPX5 mRNA CTD PMID:1301385 NCBI chr17:43,436,126...43,443,074
Ensembl chr17:43,416,340...43,443,074
JBrowse link
G Il1b interleukin 1 beta multiple interactions EXP [boldenone undecylenate results in increased abundance of boldenone] which results in increased expression of IL1B mRNA; Curcumin inhibits the reaction [[boldenone undecylenate results in increased abundance of boldenone] which results in increased expression of IL1B mRNA] CTD PMID:34719837 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Myd88 MYD88, innate immune signal transduction adaptor multiple interactions EXP [boldenone undecylenate results in increased abundance of boldenone] which results in increased expression of MYD88 mRNA; Curcumin inhibits the reaction [[boldenone undecylenate results in increased abundance of boldenone] which results in increased expression of MYD88 mRNA] CTD PMID:34719837 NCBI chr 8:119,074,439...119,078,508
Ensembl chr 8:119,074,437...119,079,415
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions EXP [boldenone undecylenate results in increased abundance of boldenone] which results in increased expression of RELA protein; Curcumin inhibits the reaction [[boldenone undecylenate results in increased abundance of boldenone] which results in increased expression of RELA protein] CTD PMID:34719837 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Tlr4 toll-like receptor 4 multiple interactions EXP [boldenone undecylenate results in increased abundance of boldenone] which results in increased expression of TLR4 protein; Curcumin inhibits the reaction [[boldenone undecylenate results in increased abundance of boldenone] which results in increased expression of TLR4 protein] CTD PMID:34719837 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628
JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP [boldenone undecylenate results in increased abundance of boldenone] which results in increased expression of TNF mRNA; Curcumin inhibits the reaction [[boldenone undecylenate results in increased abundance of boldenone] which results in increased expression of TNF mRNA] CTD PMID:34719837 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Traf6 TNF receptor associated factor 6 multiple interactions EXP [boldenone undecylenate results in increased abundance of boldenone] which results in increased expression of TRAF6 mRNA; Curcumin inhibits the reaction [[boldenone undecylenate results in increased abundance of boldenone] which results in increased expression of TRAF6 mRNA] CTD PMID:34719837 NCBI chr 3:87,963,517...87,988,316
Ensembl chr 3:87,963,514...87,983,507
JBrowse link
fluoxymesterone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hsd11b2 hydroxysteroid 11-beta dehydrogenase 2 multiple interactions
decreases activity
ISO Fluoxymesterone inhibits the reaction [HSD11B2 protein results in decreased activity of Glucocorticoids]; HSD11B2 protein binds to and results in increased metabolism of Fluoxymesterone
Fluoxymesterone results in decreased activity of HSD11B2 protein
CTD PMID:22273746 NCBI chr19:33,397,656...33,402,899
Ensembl chr19:33,397,656...33,402,899
JBrowse link
nandrolone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd86 CD86 molecule multiple interactions ISO Nandrolone promotes the reaction [endotoxin, Escherichia coli results in increased expression of CD86 protein] CTD PMID:28412309 NCBI chr11:64,142,193...64,200,816
Ensembl chr11:64,163,828...64,200,818
JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 multiple interactions ISO Nandrolone inhibits the reaction [CYP19A1 protein affects the metabolism of Androstenedione] CTD PMID:12628686 NCBI chr 8:54,552,978...54,580,375
Ensembl chr 8:54,553,165...54,580,758
JBrowse link
G Esr1 estrogen receptor 1 multiple interactions ISO Nandrolone binds to and results in increased activity of ESR1 protein CTD PMID:29162470 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
JBrowse link
G Esr2 estrogen receptor 2 affects binding EXP 19-nortestosterone binds to Esr2 protein RGD PMID:9048584 RGD:8694130 NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919
JBrowse link
G Greb1 growth regulating estrogen receptor binding 1 increases expression ISO Nandrolone results in increased expression of GREB1 mRNA CTD PMID:35307500 NCBI chr 6:39,440,522...39,562,364
Ensembl chr 6:39,440,504...39,581,633
JBrowse link
G Pgr progesterone receptor increases expression ISO Nandrolone results in increased expression of PGR mRNA CTD PMID:35307500 NCBI chr 8:6,072,673...6,131,552
Ensembl chr 8:6,072,673...6,131,344
JBrowse link
G Rack1 receptor for activated C kinase 1 increases expression
multiple interactions
ISO Nandrolone results in increased expression of RACK1 mRNA; Nandrolone results in increased expression of RACK1 protein
Flutamide inhibits the reaction [Nandrolone results in increased expression of RACK1 mRNA]
CTD PMID:28412309 NCBI chr10:33,169,415...33,174,896
Ensembl chr10:33,169,169...33,174,975
JBrowse link
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO Nandrolone inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr 1:48,121,061...48,163,268
Ensembl chr 1:48,121,061...48,163,268
JBrowse link
G Tff1 trefoil factor 1 increases expression ISO Nandrolone results in increased expression of TFF1 mRNA CTD PMID:35307500 NCBI chr20:9,235,736...9,239,597
Ensembl chr20:9,235,736...9,239,597
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO Nandrolone promotes the reaction [endotoxin, Escherichia coli results in increased expression of TNF protein] CTD PMID:28412309 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
nandrolone phenpropionate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ar androgen receptor multiple interactions
affects localization
ISO nandrolone phenpropionate binds to and results in increased activity of AR protein
nandrolone phenpropionate affects the localization of AR protein
CTD PMID:28478275 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925
JBrowse link
oxandrolone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ar androgen receptor multiple interactions ISO Oxandrolone results in increased expression of and affects the localization of AR protein CTD PMID:17364004 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925
JBrowse link
G Shbg sex hormone binding globulin decreases expression ISO Oxandrolone results in decreased expression of SHBG protein CTD PMID:17961146 NCBI chr10:54,332,939...54,350,409
Ensembl chr10:54,332,941...54,351,057
JBrowse link
oxymetholone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ar androgen receptor multiple interactions ISO Oxymetholone binds to and results in decreased activity of AR protein; Oxymetholone binds to and results in increased activity of AR protein CTD PMID:25752796 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925
JBrowse link
G Esr1 estrogen receptor 1 multiple interactions ISO Oxymetholone binds to and results in increased activity of ESR1 protein CTD PMID:25752796 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
JBrowse link
G Hsd11b2 hydroxysteroid 11-beta dehydrogenase 2 multiple interactions
decreases activity
ISO Oxymetholone inhibits the reaction [HSD11B2 protein results in decreased activity of Glucocorticoids]
Oxymetholone results in decreased activity of HSD11B2 protein
CTD PMID:22273746 NCBI chr19:33,397,656...33,402,899
Ensembl chr19:33,397,656...33,402,899
JBrowse link
G Il6 interleukin 6 decreases expression ISO Oxymetholone results in decreased expression of IL6 mRNA CTD PMID:15953861 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Il7 interleukin 7 increases expression ISO Oxymetholone results in increased expression of IL7 mRNA CTD PMID:15953861 NCBI chr 2:94,235,219...94,280,075
Ensembl chr 2:94,234,766...94,280,075
JBrowse link
G Kitlg KIT ligand increases expression ISO Oxymetholone results in increased expression of KITLG mRNA; Oxymetholone results in increased expression of KITLG protein CTD PMID:15953861 NCBI chr 7:34,896,075...34,977,215
Ensembl chr 7:34,896,053...34,977,214
JBrowse link
G Pgr progesterone receptor multiple interactions ISO Oxymetholone binds to and results in decreased activity of PGR protein CTD PMID:25752796 NCBI chr 8:6,072,673...6,131,552
Ensembl chr 8:6,072,673...6,131,344
JBrowse link
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO Oxymetholone inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr 1:48,121,061...48,163,268
Ensembl chr 1:48,121,061...48,163,268
JBrowse link
G Tpo thyroid peroxidase increases expression ISO Oxymetholone results in increased expression of TPO mRNA CTD PMID:15953861 NCBI chr 6:46,698,402...46,768,199
Ensembl chr 6:46,698,414...46,768,199
JBrowse link
stanozolol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ar androgen receptor multiple interactions
increases activity
ISO 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane inhibits the reaction [Stanozolol binds to and results in increased activity of AR protein]; 4-cumylphenol inhibits the reaction [Stanozolol binds to and results in increased activity of AR protein]; 4-tert-octylphenol inhibits the reaction [Stanozolol binds to and results in increased activity of AR protein]; bisphenol A inhibits the reaction [Stanozolol binds to and results in increased activity of AR protein]; butylbenzyl phthalate inhibits the reaction [Stanozolol binds to and results in increased activity of AR protein]; Chlordecone inhibits the reaction [Stanozolol binds to and results in increased activity of AR protein]; Corticosterone inhibits the reaction [Stanozolol binds to and results in increased activity of AR protein]; Coumestrol inhibits the reaction [Stanozolol binds to and results in increased activity of AR protein]; Diethylstilbestrol inhibits the reaction [Stanozolol binds to and results in increased activity of AR protein]; Estradiol inhibits the reaction [Stanozolol binds to and results in increased activity of AR protein]; Ethinyl Estradiol inhibits the reaction [Stanozolol binds to and results in increased activity of AR protein]; ethyl-p-hydroxybenzoate inhibits the reaction [Stanozolol binds to and results in increased activity of AR protein]; Flutamide inhibits the reaction [Stanozolol binds to and results in increased activity of AR protein]; Flutamide metabolite inhibits the reaction [Stanozolol binds to and results in increased activity of AR protein]; Genistein inhibits the reaction [Stanozolol binds to and results in increased activity of AR protein]; Hexestrol inhibits the reaction [Stanozolol binds to and results in increased activity of AR protein]; hydroxyflutamide inhibits the reaction [Stanozolol binds to and results in increased activity of AR protein]; kaempferol inhibits the reaction [Stanozolol binds to and results in increased activity of AR protein]; Ketoconazole inhibits the reaction [Stanozolol binds to and results in increased activity of AR protein]; Linuron inhibits the reaction [Stanozolol binds to and results in increased activity of AR protein]; Methoxychlor inhibits the reaction [Stanozolol binds to and results in increased activity of AR protein]; Methoxychlor inhibits the reaction [Stanozolol results in increased activity of AR protein]; Methoxychlor metabolite inhibits the reaction [Stanozolol binds to and results in increased activity of AR protein]; Reserpine inhibits the reaction [Stanozolol binds to and results in increased activity of AR protein]; Spironolactone inhibits the reaction [Stanozolol binds to and results in increased activity of AR protein]; Stanozolol binds to and results in increased activity of AR protein; Testosterone inhibits the reaction [Stanozolol binds to and results in increased activity of AR protein]; vinclozolin inhibits the reaction [Stanozolol binds to and results in increased activity of AR protein]; vinclozolin inhibits the reaction [Stanozolol results in increased activity of AR protein] CTD PMID:28009930 PMID:28377212 PMID:29162470 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925
JBrowse link
G Gpx1 glutathione peroxidase 1 decreases activity EXP Stanozolol results in decreased activity of GPX1 protein CTD PMID:36029803 NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024
JBrowse link
G Mir125b2 microRNA 125b-2 increases expression EXP Stanozolol results in increased expression of MIR125B2 CTD PMID:36029803 NCBI chr11:16,245,620...16,245,707 JBrowse link
G Mir146a microRNA 146a increases expression EXP Stanozolol results in increased expression of MIR146A CTD PMID:36029803 NCBI chr10:27,848,516...27,848,610
Ensembl chr10:27,848,516...27,848,610
JBrowse link
G Tert telomerase reverse transcriptase increases activity EXP Stanozolol results in increased activity of TERT protein CTD PMID:29717770 NCBI chr 1:29,637,213...29,659,561
Ensembl chr 1:29,637,506...29,659,561
JBrowse link
trenbolone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G App amyloid beta precursor protein multiple interactions
increases expression
affects expression
EXP Dihydrotestosterone promotes the reaction [Trenbolone Acetate analog results in increased expression of APP protein modified form]; Flutamide inhibits the reaction [Trenbolone Acetate analog results in increased expression of APP protein modified form]; fulvestrant inhibits the reaction [Trenbolone Acetate analog results in increased expression of APP protein modified form]; trilostane inhibits the reaction [Dihydrotestosterone promotes the reaction [Trenbolone Acetate analog results in increased expression of APP protein modified form]]
Trenbolone Acetate analog affects the expression of APP protein modified form
CTD PMID:25461682 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561
JBrowse link
G Ar androgen receptor multiple interactions
increases activity
affects binding
ISO
EXP
Trenbolone Acetate binds to and results in increased activity of AR protein; Trenbolone Acetate inhibits the reaction [Metribolone results in increased activity of AR protein]; triclocarban promotes the reaction [Trenbolone Acetate results in increased activity of AR protein]
Trenbolone Acetate binds to AR protein
CTD PMID:14565775 PMID:16818248 PMID:18324785 PMID:20371976 PMID:20821581 More... NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925
JBrowse link
G Casp3 caspase 3 multiple interactions
increases activity
EXP Dihydrotestosterone promotes the reaction [Trenbolone Acetate analog results in increased activity of CASP3 protein]; Flutamide promotes the reaction [Trenbolone Acetate analog results in increased activity of CASP3 protein]; fulvestrant affects the reaction [Trenbolone Acetate analog results in increased activity of CASP3 protein]; Testosterone promotes the reaction [Trenbolone Acetate analog results in increased activity of CASP3 protein]; trilostane inhibits the reaction [Dihydrotestosterone promotes the reaction [Trenbolone Acetate analog results in increased activity of CASP3 protein]] CTD PMID:25461682 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Esr1 estrogen receptor 1 multiple interactions ISO Trenbolone Acetate binds to and results in increased activity of ESR1 protein CTD PMID:33049310 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions ISO Trenbolone Acetate binds to and results in increased activity of NR1I2 protein CTD PMID:33049310 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658
JBrowse link
G Odc1 ornithine decarboxylase 1 increases expression EXP Trenbolone Acetate results in increased expression of ODC1 mRNA CTD PMID:17688994 NCBI chr 6:40,329,831...40,336,444
Ensembl chr 6:40,329,964...40,336,440
JBrowse link
G Psen1 presenilin 1 multiple interactions
decreases expression
EXP Flutamide inhibits the reaction [Trenbolone Acetate analog results in decreased expression of PSEN1 protein]; fulvestrant inhibits the reaction [Trenbolone Acetate analog results in decreased expression of PSEN1 protein]; Testosterone affects the reaction [Trenbolone Acetate analog results in decreased expression of PSEN1 protein]; Trenbolone Acetate analog inhibits the reaction [Dihydrotestosterone results in increased expression of PSEN1 protein]; trilostane inhibits the reaction [Trenbolone Acetate analog inhibits the reaction [Dihydrotestosterone results in increased expression of PSEN1 protein]] CTD PMID:25461682 NCBI chr 6:103,323,052...103,375,088
Ensembl chr 6:103,323,120...103,371,650
JBrowse link
G Thrb thyroid hormone receptor beta multiple interactions ISO Trenbolone Acetate binds to and results in increased activity of THRB protein CTD PMID:33049310 NCBI chr15:7,685,180...8,031,920
Ensembl chr15:7,685,180...7,882,916
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19878
    role 19848
      biological role 19846
        molecular messenger 18652
          hormone 18474
            steroid hormone 7892
              anabolic androgenic steroid 437
                17beta-hydroxy-17-methylestra-4,9,11-trien-3-one 411
                17beta-hydroxyandrostan-1,3-dione 0
                Delta(1)-dihydrotestosterone 0
                bolandiol + 0
                bolandiol dipropionate 0
                boldenone 7
                fluoxymesterone 1
                metholone + 0
                nandrolone + 11
                oxandrolone 2
                oxymetholone + 13
                stanozolol 5
                trenbolone 8
Path 2
Term Annotations click to browse term
  CHEBI ontology 19878
    subatomic particle 19876
      composite particle 19876
        hadron 19876
          baryon 19876
            nucleon 19876
              atomic nucleus 19876
                atom 19876
                  main group element atom 19815
                    p-block element atom 19815
                      carbon group element atom 19755
                        carbon atom 19752
                          organic molecular entity 19752
                            organic molecule 19704
                              organic cyclic compound 19493
                                organic polycyclic compound 17283
                                  steroid 14705
                                    steroid hormone 7892
                                      anabolic androgenic steroid 437
                                        17beta-hydroxy-17-methylestra-4,9,11-trien-3-one 411
                                        17beta-hydroxyandrostan-1,3-dione 0
                                        Delta(1)-dihydrotestosterone 0
                                        bolandiol + 0
                                        bolandiol dipropionate 0
                                        boldenone 7
                                        fluoxymesterone 1
                                        metholone + 0
                                        nandrolone + 11
                                        oxandrolone 2
                                        oxymetholone + 13
                                        stanozolol 5
                                        trenbolone 8
paths to the root