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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:mercaptopurine
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Accession:CHEBI:50667 term browser browse the term
Definition:A member of the class of purines that is 6,7-dihydro-1H-purine carrying a thione group at position 6. An adenine analogue, it is used in the treatment of acute lymphocytic leukemia (ALL), chronic myeloid leukemia (CML), Crohn's disease, and ulcerative colitis.
Synonyms:exact_synonym: 1,7-dihydro-6H-purine-6-thione
 related_synonym: 6 MP;   6-Mercaptopurine;   6-Thiohypoxanthine;   6-Thioxopurine;   Formula=C5H4N4S;   InChI=1S/C5H4N4S/c10-5-3-4(7-1-6-3)8-2-9-5/h1-2H,(H2,6,7,8,9,10);   InChIKey=GLVAUDGFNGKCSF-UHFFFAOYSA-N;   Mercaptopurina;   Mercapurin;   Puri-Nethol;   Purinethol;   SMILES=S=c1[nH]cnc2nc[nH]c12;   mercaptopurinum
 xref: CAS:50-44-2;   DrugBank:DB01033;   KEGG:C02380;   KEGG:D04931
 xref_mesh: MESH:D015122
 xref: PDBeChem:PM6;   PMID:16267626;   PMID:28011186;   PMID:28166217;   PMID:28212467;   PMID:28295989;   PMID:28301625;   PMID:28406092;   PMID:28418010;   PMID:28484608;   PMID:28574837;   Patent:US2697709;   Patent:US2721866;   Reaxys:132916
 cyclic_relationship: is_tautomer_of CHEBI:2208


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mercaptopurine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc8 ATP binding cassette subfamily C member 8 decreases expression EXP Mercaptopurine results in decreased expression of ABCC8 mRNA CTD PMID:23358152 NCBI chr 1:96,598,568...96,679,563
Ensembl chr 1:96,598,647...96,679,510 		JBrowse link
G Acer2 alkaline ceramidase 2 increases expression EXP Mercaptopurine results in increased expression of ACER2 mRNA CTD PMID:23358152 NCBI chr 5:101,391,830...101,442,615
Ensembl chr 5:101,391,885...101,442,614 		JBrowse link
G Acod1 aconitate decarboxylase 1 increases expression EXP Mercaptopurine results in increased expression of ACOD1 mRNA CTD PMID:23358152 NCBI chr15:79,871,819...79,881,101
Ensembl chr15:79,871,827...79,880,529 		JBrowse link
G Actg2 actin gamma 2, smooth muscle decreases expression EXP Mercaptopurine results in decreased expression of ACTG2 mRNA CTD PMID:23358152 NCBI chr 4:116,021,832...116,046,475
Ensembl chr 4:116,021,832...116,046,465 		JBrowse link
G Actrt3 actin-related protein T3 increases expression EXP Mercaptopurine results in increased expression of ACTRT3 mRNA CTD PMID:23358152 NCBI chr 2:112,799,038...112,801,065
Ensembl chr 2:112,799,011...112,801,075 		JBrowse link
G Adm adrenomedullin increases expression EXP Mercaptopurine results in increased expression of ADM mRNA CTD PMID:23358152 NCBI chr 1:164,745,484...164,747,655
Ensembl chr 1:164,745,466...164,747,654 		JBrowse link
G Agt angiotensinogen decreases expression EXP Mercaptopurine results in decreased expression of AGT mRNA CTD PMID:23358152 NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977 		JBrowse link
G Agxt alanine--glyoxylate aminotransferase increases expression EXP Mercaptopurine results in increased expression of AGXT mRNA CTD PMID:23358152 NCBI chr 9:93,675,384...93,685,337
Ensembl chr 9:93,675,384...93,685,336 		JBrowse link
G Akap12 A-kinase anchoring protein 12 decreases expression EXP Mercaptopurine results in decreased expression of AKAP12 mRNA CTD PMID:23358152 NCBI chr 1:40,730,123...40,819,863
Ensembl chr 1:40,730,123...40,819,886 		JBrowse link
G Akap3 A-kinase anchoring protein 3 increases expression EXP Mercaptopurine results in increased expression of AKAP3 mRNA CTD PMID:23358152 NCBI chr 4:159,688,049...159,714,067
Ensembl chr 4:159,699,289...159,713,903 		JBrowse link
G Aldh1b1 aldehyde dehydrogenase 1 family, member B1 decreases expression EXP Mercaptopurine results in decreased expression of ALDH1B1 mRNA CTD PMID:23358152 NCBI chr 5:60,063,370...60,068,378
Ensembl chr 5:60,063,225...60,068,378 		JBrowse link
G Alox15 arachidonate 15-lipoxygenase decreases expression EXP Mercaptopurine results in decreased expression of ALOX15 mRNA CTD PMID:23358152 NCBI chr10:55,060,169...55,068,885
Ensembl chr10:55,060,412...55,068,874 		JBrowse link
G Alpi alkaline phosphatase, intestinal decreases expression EXP Mercaptopurine results in decreased expression of ALPI mRNA CTD PMID:23358152 NCBI chr 9:87,773,411...87,776,877
Ensembl chr 9:87,773,411...87,776,877 		JBrowse link
G Ampd3 adenosine monophosphate deaminase 3 increases expression EXP Mercaptopurine results in increased expression of AMPD3 mRNA CTD PMID:23358152 NCBI chr 1:164,884,823...164,929,899
Ensembl chr 1:164,885,320...164,929,887 		JBrowse link
G Angpt2 angiopoietin 2 increases expression EXP Mercaptopurine results in increased expression of ANGPT2 mRNA CTD PMID:23358152 NCBI chr16:71,088,364...71,138,805
Ensembl chr16:71,088,364...71,138,804 		JBrowse link
G Anxa9 annexin A9 decreases expression EXP Mercaptopurine results in decreased expression of ANXA9 mRNA CTD PMID:23358152 NCBI chr 2:182,873,185...182,884,501
Ensembl chr 2:182,872,929...182,883,374 		JBrowse link
G Apoc3 apolipoprotein C3 decreases expression EXP Mercaptopurine results in decreased expression of APOC3 mRNA CTD PMID:23358152 NCBI chr 8:46,531,478...46,533,658
Ensembl chr 8:46,531,478...46,533,583 		JBrowse link
G Art3 ADP-ribosyltransferase 3 increases expression EXP Mercaptopurine results in increased expression of ART3 mRNA CTD PMID:23358152 NCBI chr14:15,637,230...15,719,442
Ensembl chr14:15,637,237...15,665,407 		JBrowse link
G Asb14 ankyrin repeat and SOCS box-containing 14 increases expression EXP Mercaptopurine results in increased expression of ASB14 mRNA CTD PMID:23358152 NCBI chr16:2,095,567...2,123,259
Ensembl chr16:2,095,644...2,115,135 		JBrowse link
G Asprv1 aspartic peptidase, retroviral-like 1 increases expression EXP Mercaptopurine results in increased expression of ASPRV1 mRNA CTD PMID:23358152 NCBI chr 4:119,077,415...119,078,887
Ensembl chr 4:119,077,356...119,078,379 		JBrowse link
G Atp2a3 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3 decreases expression EXP Mercaptopurine results in decreased expression of ATP2A3 mRNA CTD PMID:23358152 NCBI chr10:57,581,742...57,612,758
Ensembl chr10:57,582,128...57,612,748 		JBrowse link
G Bard1 BRCA1 associated RING domain 1 decreases expression EXP Mercaptopurine results in decreased expression of BARD1 mRNA CTD PMID:23358152 NCBI chr 9:72,616,070...72,694,553
Ensembl chr 9:72,623,155...72,694,265 		JBrowse link
G Batf3 basic leucine zipper ATF-like transcription factor 3 decreases expression EXP Mercaptopurine results in decreased expression of BATF3 mRNA CTD PMID:23358152 NCBI chr13:102,689,657...102,701,241
Ensembl chr13:102,689,657...102,701,139 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression ISO Mercaptopurine results in increased expression of BAX protein CTD PMID:9058596 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression
multiple interactions		 ISO Mercaptopurine results in decreased expression of BCL2 protein
[Doxorubicin co-treated with Dexamethasone co-treated with Vincristine co-treated with Cytarabine co-treated with Mercaptopurine co-treated with Methotrexate co-treated with Cyclophosphamide co-treated with Enzymes and Coenzymes] results in increased expression of BCL2 protein		 CTD PMID:9058596 PMID:21182165 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Bcl2l1 Bcl2-like 1 decreases expression ISO Mercaptopurine results in decreased expression of BCL2L1 protein CTD PMID:12697733 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
Ensembl chr 1:141,253,523...141,303,479 		JBrowse link
G Bcorl1 BCL6 co-repressor-like 1 decreases expression EXP Mercaptopurine results in decreased expression of BCORL1 mRNA CTD PMID:23358152 NCBI chr  X:127,516,504...127,584,529
Ensembl chr  X:127,537,538...127,584,087 		JBrowse link
G Bspry B-box and SPRY domain containing decreases expression EXP Mercaptopurine results in decreased expression of BSPRY mRNA CTD PMID:23358152 NCBI chr 5:75,927,397...75,949,585
Ensembl chr 5:75,927,405...75,949,583 		JBrowse link
G Btbd16 BTB domain containing 16 increases expression EXP Mercaptopurine results in increased expression of BTBD16 mRNA CTD PMID:23358152 NCBI chr 1:185,334,971...185,389,518
Ensembl chr 1:185,335,725...185,389,517 		JBrowse link
G C1qa complement C1q A chain increases expression EXP Mercaptopurine results in increased expression of C1QA mRNA CTD PMID:23358152 NCBI chr 5:149,133,635...149,136,482
Ensembl chr 5:149,133,636...149,136,534 		JBrowse link
G Cap2 cyclase associated actin cytoskeleton regulatory protein 2 increases expression EXP Mercaptopurine results in increased expression of CAP2 mRNA CTD PMID:23358152 NCBI chr17:18,054,234...18,203,453
Ensembl chr17:18,054,431...18,203,373 		JBrowse link
G Car4 carbonic anhydrase 4 decreases expression EXP Mercaptopurine results in decreased expression of CAR4 mRNA CTD PMID:23358152 NCBI chr10:69,827,945...69,836,501
Ensembl chr10:69,827,945...69,836,501 		JBrowse link
G Car7 carbonic anhydrase 7 decreases expression EXP Mercaptopurine results in decreased expression of CAR7 mRNA CTD PMID:23358152 NCBI chr19:429,063...438,478
Ensembl chr19:429,075...438,467 		JBrowse link
G Casp3 caspase 3 increases expression EXP Mercaptopurine results in increased expression of CASP3 protein CTD PMID:22688000 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Ccl5 C-C motif chemokine ligand 5 decreases expression EXP Mercaptopurine results in decreased expression of CCL5 mRNA CTD PMID:23358152 NCBI chr10:68,322,826...68,327,380
Ensembl chr10:68,322,829...68,327,377 		JBrowse link
G Ccne1 cyclin E1 decreases expression EXP Mercaptopurine results in decreased expression of CCNE1 mRNA CTD PMID:23358152 NCBI chr 1:90,781,947...90,791,188
Ensembl chr 1:90,781,949...90,791,101 		JBrowse link
G Ccr6 C-C motif chemokine receptor 6 decreases expression EXP Mercaptopurine results in decreased expression of CCR6 mRNA CTD PMID:23358152 NCBI chr 1:52,474,477...52,508,301
Ensembl chr 1:52,474,168...52,498,603 		JBrowse link
G Cd19 CD19 molecule decreases expression EXP Mercaptopurine results in decreased expression of CD19 mRNA CTD PMID:23358152 NCBI chr 1:180,987,286...180,993,920
Ensembl chr 1:180,987,286...180,993,975 		JBrowse link
G Cd28 Cd28 molecule multiple interactions ISO Mercaptopurine inhibits the reaction [CD28 protein results in increased activity of [NFKB1 protein binds to RELA protein]] CTD PMID:12697733 NCBI chr 9:62,166,324...62,194,674
Ensembl chr 9:62,166,192...62,194,685 		JBrowse link
G Cd68 Cd68 molecule increases expression EXP Mercaptopurine results in increased expression of CD68 mRNA CTD PMID:23358152 NCBI chr10:54,381,814...54,383,693
Ensembl chr10:54,381,815...54,383,697 		JBrowse link
G Cd79b CD79b molecule decreases expression EXP Mercaptopurine results in decreased expression of CD79B mRNA CTD PMID:23358152 NCBI chr10:91,239,354...91,242,500
Ensembl chr10:91,239,356...91,242,625 		JBrowse link
G Cdc25b cell division cycle 25B decreases expression EXP Mercaptopurine results in decreased expression of CDC25B mRNA CTD PMID:23358152 NCBI chr 3:118,407,127...118,417,272
Ensembl chr 3:118,407,128...118,417,272 		JBrowse link
G Cdca3 cell division cycle associated 3 decreases expression EXP Mercaptopurine results in decreased expression of CDCA3 mRNA CTD PMID:23358152 NCBI chr 4:157,634,775...157,638,799
Ensembl chr 4:157,634,928...157,638,799 		JBrowse link
G Cdca7l cell division cycle associated 7 like decreases expression EXP Mercaptopurine results in decreased expression of CDCA7L mRNA CTD PMID:23358152 NCBI chr 6:138,793,953...138,839,889
Ensembl chr 6:138,794,228...138,839,888 		JBrowse link
G Cela1 chymotrypsin like elastase 1 increases expression EXP Mercaptopurine results in increased expression of CELA1 mRNA CTD PMID:23358152 NCBI chr 7:131,773,161...131,786,300
Ensembl chr 7:131,742,002...131,786,285 		JBrowse link
G Cenpw centromere protein W decreases expression EXP Mercaptopurine results in decreased expression of CENPW mRNA CTD PMID:23358152 NCBI chr 1:27,525,324...27,530,464
Ensembl chr 1:27,525,324...27,530,464 		JBrowse link
G Ces3a carboxylesterase 3a increases expression EXP Mercaptopurine results in increased expression of CES3 mRNA CTD PMID:23358152 NCBI chr19:32,992,386...33,000,562 JBrowse link
G Ces4a carboxylesterase 4A increases expression EXP Mercaptopurine results in increased expression of CES4A mRNA CTD PMID:23358152 NCBI chr19:33,011,731...33,030,119
Ensembl chr19:33,011,731...33,029,545 		JBrowse link
G Chrd chordin increases expression EXP Mercaptopurine results in increased expression of CHRD mRNA CTD PMID:23358152 NCBI chr11:80,171,994...80,181,166
Ensembl chr11:80,171,994...80,180,673 		JBrowse link
G Chrdl1 chordin-like 1 decreases expression EXP Mercaptopurine results in decreased expression of CHRDL1 mRNA CTD PMID:23358152 NCBI chr  X:106,889,125...106,992,937
Ensembl chr  X:106,889,125...106,992,921 		JBrowse link
G Chrna2 cholinergic receptor nicotinic alpha 2 subunit decreases expression EXP Mercaptopurine results in decreased expression of CHRNA2 mRNA CTD PMID:23358152 NCBI chr15:40,342,317...40,358,601
Ensembl chr15:40,342,317...40,358,601 		JBrowse link
G Clec14a C-type lectin domain containing 14A decreases expression EXP Mercaptopurine results in decreased expression of CLEC14A mRNA CTD PMID:23358152 NCBI chr 6:75,881,470...75,884,612
Ensembl chr 6:75,881,473...75,884,612 		JBrowse link
G Clec4d C-type lectin domain family 4, member D increases expression EXP Mercaptopurine results in increased expression of CLEC4D mRNA CTD PMID:23358152 NCBI chr 4:156,589,591...156,599,279
Ensembl chr 4:156,589,792...156,598,848 		JBrowse link
G Clgn calmegin decreases expression EXP Mercaptopurine results in decreased expression of CLGN mRNA CTD PMID:23358152 NCBI chr19:24,695,140...24,728,542
Ensembl chr19:24,696,875...24,728,758 		JBrowse link
G Clic2 chloride intracellular channel 2 increases expression EXP Mercaptopurine results in increased expression of CLIC2 mRNA CTD PMID:23358152 NCBI chr20:149,337...164,375
Ensembl chr20:148,907...164,355 		JBrowse link
G Cnmd chondromodulin decreases expression EXP Mercaptopurine results in decreased expression of CNMD mRNA CTD PMID:23358152 NCBI chr15:55,041,548...55,066,297
Ensembl chr15:55,041,561...55,066,297 		JBrowse link
G Col11a1 collagen type XI alpha 1 chain decreases expression EXP Mercaptopurine results in decreased expression of COL11A1 mRNA CTD PMID:23358152 NCBI chr 2:201,820,715...202,013,853
Ensembl chr 2:201,820,715...202,013,853 		JBrowse link
G Col1a1 collagen type I alpha 1 chain decreases expression EXP Mercaptopurine results in decreased expression of COL1A1 mRNA CTD PMID:23358152 NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624 		JBrowse link
G Col2a1 collagen type II alpha 1 chain decreases expression EXP Mercaptopurine results in decreased expression of COL2A1 mRNA CTD PMID:23358152 NCBI chr 7:129,098,489...129,127,560
Ensembl chr 7:129,098,786...129,127,546 		JBrowse link
G Corin corin, serine peptidase increases expression EXP Mercaptopurine results in increased expression of CORIN mRNA CTD PMID:23358152 NCBI chr14:35,680,601...35,910,703
Ensembl chr14:35,681,304...35,909,503 		JBrowse link
G Coro6 coronin 6 increases expression EXP Mercaptopurine results in increased expression of CORO6 mRNA CTD PMID:23358152 NCBI chr10:62,311,552...62,319,659
Ensembl chr10:62,311,660...62,319,659 		JBrowse link
G Cpe carboxypeptidase E increases expression EXP Mercaptopurine results in increased expression of CPE mRNA CTD PMID:23358152 NCBI chr16:25,030,276...25,142,231
Ensembl chr16:25,030,276...25,142,233 		JBrowse link
G Ctsk cathepsin K increases expression EXP Mercaptopurine results in increased expression of CTSK mRNA CTD PMID:23358152 NCBI chr 2:183,058,586...183,069,551
Ensembl chr 2:183,058,569...183,069,550 		JBrowse link
G Ctsql2 cathepsin Q-like 2 increases expression EXP Mercaptopurine results in increased expression of CTSQL2 mRNA CTD PMID:23358152 NCBI chr17:3,698,973...3,704,787
Ensembl chr17:3,698,918...3,704,685 		JBrowse link
G Ctxn3 cortexin 3 increases expression EXP Mercaptopurine results in increased expression of CTXN3 mRNA CTD PMID:23358152 NCBI chr18:50,930,244...50,940,642
Ensembl chr18:50,930,235...50,940,641 		JBrowse link
G Cubn cubilin decreases expression EXP Mercaptopurine results in decreased expression of CUBN mRNA CTD PMID:23358152 NCBI chr17:76,385,046...76,593,133
Ensembl chr17:76,385,060...76,593,231 		JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 increases expression EXP Mercaptopurine results in increased expression of CXCL2 mRNA CTD PMID:23358152 NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075 		JBrowse link
G Cyp26a1 cytochrome P450, family 26, subfamily a, polypeptide 1 increases expression EXP Mercaptopurine results in increased expression of CYP26A1 mRNA CTD PMID:23358152 NCBI chr 1:235,471,368...235,475,204
Ensembl chr 1:235,471,298...235,475,204 		JBrowse link
G Cyp2j4 cytochrome P450, family 2, subfamily j, polypeptide 4 increases expression EXP Mercaptopurine results in increased expression of CYP2J4 mRNA CTD PMID:23358152 NCBI chr 5:111,179,981...111,207,490
Ensembl chr 5:111,178,703...111,244,794 		JBrowse link
G Cyp4a3 cytochrome P450, family 4, subfamily a, polypeptide 3 increases expression EXP Mercaptopurine results in increased expression of CYP4A3 mRNA CTD PMID:23358152 NCBI chr 5:129,097,571...129,115,488
Ensembl chr 5:129,097,926...129,115,463 		JBrowse link
G Dcaf12l1 DDB1 and CUL4 associated factor 12-like 1 decreases expression EXP Mercaptopurine results in decreased expression of DCAF12L1 mRNA CTD PMID:23358152 NCBI chr  X:123,695,286...123,698,905
Ensembl chr  X:123,695,286...123,698,905 		JBrowse link
G Def6 DEF6 guanine nucleotide exchange factor increases expression EXP Mercaptopurine results in increased expression of DEF6 mRNA CTD PMID:23358152 NCBI chr20:6,268,579...6,290,030
Ensembl chr20:6,268,601...6,289,961 		JBrowse link
G Dhrs9 dehydrogenase/reductase 9 increases expression EXP Mercaptopurine results in increased expression of DHRS9 mRNA CTD PMID:23358152 NCBI chr 3:54,147,834...54,170,052
Ensembl chr 3:54,147,803...54,220,241 		JBrowse link
G Dio2 iodothyronine deiodinase 2 increases expression EXP Mercaptopurine results in increased expression of DIO2 mRNA CTD PMID:23358152 NCBI chr 6:109,665,523...109,679,809
Ensembl chr 6:109,665,523...109,679,809 		JBrowse link
G Dkkl1 dickkopf like acrosomal protein 1 decreases expression EXP Mercaptopurine results in decreased expression of DKKL1 mRNA CTD PMID:23358152 NCBI chr 1:95,694,010...95,699,259
Ensembl chr 1:95,694,010...95,699,259 		JBrowse link
G Dlk2 delta like non-canonical Notch ligand 2 increases expression EXP Mercaptopurine results in increased expression of DLK2 mRNA CTD PMID:23358152 NCBI chr 9:14,677,102...14,681,584
Ensembl chr 9:14,676,562...14,681,594 		JBrowse link
G Dll3 delta like canonical Notch ligand 3 decreases expression EXP Mercaptopurine results in decreased expression of DLL3 mRNA CTD PMID:23358152 NCBI chr 1:83,562,011...83,570,008
Ensembl chr 1:83,562,014...83,569,750 		JBrowse link
G Drd4 dopamine receptor D4 increases expression EXP Mercaptopurine results in increased expression of DRD4 mRNA CTD PMID:23358152 NCBI chr 1:196,396,366...196,400,824
Ensembl chr 1:196,396,366...196,399,553 		JBrowse link
G Duox2 dual oxidase 2 increases expression EXP Mercaptopurine results in increased expression of DUOX2 mRNA CTD PMID:23358152 NCBI chr 3:109,223,809...109,247,023
Ensembl chr 3:109,226,924...109,245,902 		JBrowse link
G Efemp1 EGF containing fibulin extracellular matrix protein 1 increases expression EXP Mercaptopurine results in increased expression of EFEMP1 mRNA CTD PMID:23358152 NCBI chr14:102,610,813...102,690,027
Ensembl chr14:102,610,908...102,690,018 		JBrowse link
G Efna1 ephrin A1 multiple interactions EXP Mercaptopurine promotes the reaction [GW 1929 results in increased expression of EFNA1 mRNA] CTD PMID:27435855 NCBI chr 2:174,681,676...174,689,061
Ensembl chr 2:174,681,682...174,690,866 		JBrowse link
G Ehd3 EH-domain containing 3 increases expression EXP Mercaptopurine results in increased expression of EHD3 mRNA CTD PMID:23358152 NCBI chr 6:21,640,861...21,665,601
Ensembl chr 6:21,639,290...21,665,236 		JBrowse link
G Elf5 E74 like ETS transcription factor 5 decreases expression EXP Mercaptopurine results in decreased expression of ELF5 mRNA CTD PMID:23358152 NCBI chr 3:89,808,837...89,836,977
Ensembl chr 3:89,797,880...89,836,973 		JBrowse link
G Emcn endomucin decreases expression EXP Mercaptopurine results in decreased expression of EMCN mRNA CTD PMID:23358152 NCBI chr 2:225,891,100...225,970,932
Ensembl chr 2:225,891,100...225,970,929 		JBrowse link
G Enpp2 ectonucleotide pyrophosphatase/phosphodiesterase 2 decreases expression EXP Mercaptopurine results in decreased expression of ENPP2 mRNA CTD PMID:23358152 NCBI chr 7:86,202,345...86,325,050
Ensembl chr 7:86,202,350...86,324,827 		JBrowse link
G Epb41l3 erythrocyte membrane protein band 4.1-like 3 decreases expression EXP Mercaptopurine results in decreased expression of EPB41L3 mRNA CTD PMID:23358152 NCBI chr 9:109,056,178...109,260,607
Ensembl chr 9:109,016,113...109,260,607 		JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 decreases expression EXP Mercaptopurine results in decreased expression of ERBB2 mRNA CTD PMID:23358152 NCBI chr10:83,411,197...83,435,078
Ensembl chr10:83,411,313...83,435,078 		JBrowse link
G Erhl1 ERH, mRNA splicing and mitosis factor like 1 decreases expression EXP Mercaptopurine results in decreased expression of ERHL1 mRNA CTD PMID:23358152 NCBI chr 2:132,570,276...132,573,582
Ensembl chr 2:132,570,285...132,573,604 		JBrowse link
G Ervfrd-1 endogenous retrovirus group FRD member 1, envelope decreases expression EXP Mercaptopurine results in decreased expression of ERVFRD-1 mRNA CTD PMID:23358152 NCBI chr12:22,151,211...22,158,264
Ensembl chr12:22,151,211...22,158,264 		JBrowse link
G Esr1 estrogen receptor 1 increases expression EXP Mercaptopurine results in increased expression of ESR1 mRNA CTD PMID:23358152 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002 		JBrowse link
G F13a1 coagulation factor XIII A1 chain increases expression EXP Mercaptopurine results in increased expression of F13A1 mRNA CTD PMID:23358152 NCBI chr17:27,815,723...27,992,494
Ensembl chr17:27,815,702...27,992,700 		JBrowse link
G Fam25a family with sequence similarity 25, member A increases expression EXP Mercaptopurine results in increased expression of FAM25A mRNA CTD PMID:23358152 NCBI chr16:9,680,668...9,684,474
Ensembl chr16:9,680,668...9,684,474 		JBrowse link
G Fcgr3a Fc gamma receptor 3A increases expression EXP Mercaptopurine results in increased expression of FCGR3A mRNA CTD PMID:23358152 NCBI chr13:83,249,905...83,259,921
Ensembl chr13:83,249,872...83,259,921 		JBrowse link
G Fcnb ficolin B increases expression EXP Mercaptopurine results in increased expression of FCN1 mRNA CTD PMID:23358152 NCBI chr 3:11,393,713...11,402,198
Ensembl chr 3:11,393,739...11,402,151 		JBrowse link
G Ftl1 ferritin light chain 1 increases expression EXP Mercaptopurine results in increased expression of FTL mRNA CTD PMID:27435855 NCBI chr 1:95,936,387...95,938,234
Ensembl chr 1:95,936,387...95,939,725
Ensembl chr10:95,936,387...95,939,725
Ensembl chr 2:95,936,387...95,939,725 		JBrowse link
G G0s2 G0/G1switch 2 increases expression EXP Mercaptopurine results in increased expression of G0S2 mRNA CTD PMID:23358152 NCBI chr13:104,806,351...104,807,263
Ensembl chr13:104,806,156...104,807,451 		JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase affects localization ISO Mercaptopurine affects the localization of GAPDH protein CTD PMID:19628630 NCBI chr 4:157,962,312...157,967,158
Ensembl chr 4:157,962,343...157,966,235 		JBrowse link
G Gatm glycine amidinotransferase increases expression EXP Mercaptopurine results in increased expression of GATM mRNA CTD PMID:23358152 NCBI chr 3:109,658,919...109,675,508
Ensembl chr 3:109,658,951...109,684,129 		JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit increases expression ISO Mercaptopurine results in increased expression of GCLM mRNA CTD PMID:18222062 NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535 		JBrowse link
G Gcm1 glial cells missing transcription factor 1 decreases expression EXP Mercaptopurine results in decreased expression of GCM1 mRNA CTD PMID:23358152 NCBI chr 8:78,925,687...78,938,924
Ensembl chr 8:78,925,687...78,938,924 		JBrowse link
G Gdf9 growth differentiation factor 9 increases expression EXP Mercaptopurine results in increased expression of GDF9 mRNA CTD PMID:23358152 NCBI chr10:37,589,200...37,599,970
Ensembl chr10:37,595,679...37,599,672 		JBrowse link
G Ghrl ghrelin and obestatin prepropeptide decreases expression EXP Mercaptopurine results in decreased expression of GHRL mRNA CTD PMID:23358152 NCBI chr 4:146,865,712...146,869,621
Ensembl chr 4:146,865,712...146,869,621 		JBrowse link
G Gjb4 gap junction protein, beta 4 increases expression EXP Mercaptopurine results in increased expression of GJB4 mRNA CTD PMID:23358152 NCBI chr 5:139,675,776...139,679,551
Ensembl chr 5:139,675,780...139,679,667 		JBrowse link
G Gng8 G protein subunit gamma 8 increases expression EXP Mercaptopurine results in increased expression of GNG8 mRNA CTD PMID:23358152 NCBI chr 1:77,564,512...77,568,371
Ensembl chr 1:77,564,515...77,568,371 		JBrowse link
G Gpx2 glutathione peroxidase 2 increases expression ISO Mercaptopurine results in increased expression of GPX2 mRNA CTD PMID:18222062 NCBI chr 6:95,493,589...95,496,877
Ensembl chr 6:95,493,589...95,496,877 		JBrowse link
G Gpx3 glutathione peroxidase 3 increases expression ISO Mercaptopurine results in increased expression of GPX3 mRNA CTD PMID:18222062 NCBI chr10:39,028,624...39,036,695
Ensembl chr10:39,028,570...39,037,035 		JBrowse link
G Grem1 gremlin 1, DAN family BMP antagonist increases expression EXP Mercaptopurine results in increased expression of GREM1 mRNA CTD PMID:23358152 NCBI chr 3:100,512,317...100,524,001
Ensembl chr 3:100,512,313...100,524,082 		JBrowse link
G Grp gastrin releasing peptide increases expression EXP Mercaptopurine results in increased expression of GRP mRNA CTD PMID:23358152 NCBI chr18:59,388,679...59,402,061
Ensembl chr18:59,388,274...59,402,061 		JBrowse link
G Grxcr2 glutaredoxin and cysteine rich domain containing 2 increases expression EXP Mercaptopurine results in increased expression of GRXCR2 mRNA CTD PMID:23358152 NCBI chr18:33,984,689...33,998,094
Ensembl chr18:33,984,689...33,998,094 		JBrowse link
G Gss glutathione synthetase increases expression ISO Mercaptopurine results in increased expression of GSS mRNA CTD PMID:18222062 NCBI chr 3:144,047,849...144,078,197
Ensembl chr 3:144,047,850...144,078,198 		JBrowse link
G Gstm1 glutathione S-transferase mu 1 affects response to substance ISO GSTM1 gene polymorphism affects the susceptibility to Mercaptopurine CTD PMID:15713801 NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411 		JBrowse link
G Guca2a guanylate cyclase activator 2A increases expression EXP Mercaptopurine results in increased expression of GUCA2A mRNA CTD PMID:23358152 NCBI chr 5:133,237,177...133,239,019
Ensembl chr 5:133,237,177...133,239,018 		JBrowse link
G Gzmb granzyme B increases expression EXP Mercaptopurine results in increased expression of GZMB mRNA CTD PMID:23358152 NCBI chr15:30,343,352...30,346,814
Ensembl chr15:30,173,603...30,346,814 		JBrowse link
G Gzmbl1 Granszyme B-like 1 increases expression EXP Mercaptopurine results in increased expression of GZMBL1 mRNA CTD PMID:23358152 NCBI chr15:30,086,674...30,090,455
Ensembl chr15:30,087,130...30,090,037 		JBrowse link
G Hamp hepcidin antimicrobial peptide increases expression EXP Mercaptopurine results in increased expression of HAMP mRNA CTD PMID:23358152 NCBI chr 1:86,170,926...86,172,865
Ensembl chr 1:86,170,901...86,172,891 		JBrowse link
G Hand2 heart and neural crest derivatives expressed 2 increases expression EXP Mercaptopurine results in increased expression of HAND2 mRNA CTD PMID:23358152 NCBI chr16:32,917,448...32,920,791
Ensembl chr16:32,917,823...32,919,891 		JBrowse link
G Hbb hemoglobin subunit beta decreases expression EXP Mercaptopurine results in decreased expression of HBB mRNA; Mercaptopurine results in decreased expression of HBB-B1 mRNA CTD PMID:23358152 NCBI chr 1:158,250,421...158,251,832
Ensembl chr 1:158,120,200...158,252,012 		JBrowse link
G Hbe2 hemoglobin, epsilon 2 decreases expression EXP Mercaptopurine results in decreased expression of HBE2 mRNA CTD PMID:23358152 NCBI chr 1:158,279,285...158,280,913
Ensembl chr 1:158,279,285...158,280,913 		JBrowse link
G Hbegf heparin-binding EGF-like growth factor decreases expression EXP Mercaptopurine results in decreased expression of HBEGF mRNA CTD PMID:23358152 NCBI chr18:28,106,284...28,116,167
Ensembl chr18:28,105,760...28,116,441 		JBrowse link
G Heph hephaestin decreases expression EXP Mercaptopurine results in decreased expression of HEPH mRNA CTD PMID:23358152 NCBI chr  X:61,151,131...61,402,980
Ensembl chr  X:61,296,345...61,402,980 		JBrowse link
G Hoxa13 homeo box A13 decreases expression EXP Mercaptopurine results in decreased expression of HOXA13 mRNA CTD PMID:23358152 NCBI chr 4:81,358,956...81,361,091
Ensembl chr 4:81,358,956...81,361,091 		JBrowse link
G Hpgds hematopoietic prostaglandin D synthase increases expression EXP Mercaptopurine results in increased expression of HPGDS mRNA CTD PMID:23358152 NCBI chr 4:94,368,426...94,397,931
Ensembl chr 4:94,373,342...94,397,883 		JBrowse link
G Hpx hemopexin increases expression EXP Mercaptopurine results in increased expression of HPX mRNA CTD PMID:23358152 NCBI chr 1:159,932,819...159,940,327
Ensembl chr 1:159,932,755...159,940,328 		JBrowse link
G Hsd11b1 hydroxysteroid 11-beta dehydrogenase 1 increases expression EXP Mercaptopurine results in increased expression of HSD11B1 mRNA CTD PMID:23358152 NCBI chr13:104,728,539...104,798,884
Ensembl chr13:104,728,539...104,788,687 		JBrowse link
G Htr2b 5-hydroxytryptamine receptor 2B increases expression EXP Mercaptopurine results in increased expression of HTR2B mRNA CTD PMID:23358152 NCBI chr 9:86,735,793...86,756,638
Ensembl chr 9:86,742,102...86,755,108 		JBrowse link
G Htra3 HtrA serine peptidase 3 increases expression EXP Mercaptopurine results in increased expression of HTRA3 mRNA CTD PMID:23358152 NCBI chr14:75,068,917...75,097,315
Ensembl chr14:75,068,917...75,097,315 		JBrowse link
G Htra4 HtrA serine peptidase 4 increases expression EXP Mercaptopurine results in increased expression of HTRA4 mRNA CTD PMID:23358152 NCBI chr16:67,001,605...67,015,074
Ensembl chr16:67,001,605...67,015,074 		JBrowse link
G Ifit1 interferon-induced protein with tetratricopeptide repeats 1 increases expression EXP Mercaptopurine results in increased expression of IFIT1 mRNA CTD PMID:23358152 NCBI chr 1:232,152,038...232,154,103
Ensembl chr 1:232,127,170...232,154,435 		JBrowse link
G Igsf11 immunoglobulin superfamily, member 11 increases expression EXP Mercaptopurine results in increased expression of IGSF11 mRNA CTD PMID:23358152 NCBI chr11:61,733,139...61,884,059
Ensembl chr11:61,733,144...61,868,348 		JBrowse link
G Il1rn interleukin 1 receptor antagonist increases expression EXP Mercaptopurine results in increased expression of IL1RN mRNA CTD PMID:23358152 NCBI chr 3:7,111,567...7,127,451
Ensembl chr 3:7,111,550...7,127,445 		JBrowse link
G Il23r interleukin 23 receptor increases expression EXP Mercaptopurine results in increased expression of IL23R mRNA CTD PMID:23358152 NCBI chr 4:96,580,568...96,672,540
Ensembl chr 4:96,580,714...96,674,021 		JBrowse link
G Impdh2 inosine monophosphate dehydrogenase 2 increases expression ISO Mercaptopurine results in increased expression of IMPDH2 mRNA CTD PMID:18222062 NCBI chr 8:109,256,705...109,261,365
Ensembl chr 8:109,256,728...109,261,359 		JBrowse link
G Ins2 insulin 2 decreases expression EXP Mercaptopurine results in decreased expression of INS2 mRNA CTD PMID:23358152 NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775 		JBrowse link
G Irx4 iroquois homeobox 4 decreases expression EXP Mercaptopurine results in decreased expression of IRX4 mRNA CTD PMID:23358152 NCBI chr 1:30,030,561...30,039,549
Ensembl chr 1:30,030,561...30,039,549 		JBrowse link
G Jam2 junctional adhesion molecule 2 increases expression EXP Mercaptopurine results in increased expression of JAM2 mRNA CTD PMID:23358152 NCBI chr11:23,830,820...23,880,071
Ensembl chr11:23,831,106...23,880,063 		JBrowse link
G Kcnmb4 potassium calcium-activated channel subfamily M regulatory beta subunit 4 increases expression EXP Mercaptopurine results in increased expression of KCNMB4 mRNA CTD PMID:23358152 NCBI chr 7:52,066,145...52,119,098
Ensembl chr 7:52,066,136...52,119,278 		JBrowse link
G Kcnq2 potassium voltage-gated channel subfamily Q member 2 decreases expression EXP Mercaptopurine results in decreased expression of KCNQ2 mRNA CTD PMID:23358152 NCBI chr 3:168,194,776...168,253,831
Ensembl chr 3:168,195,357...168,275,071 		JBrowse link
G Kcnt1 potassium sodium-activated channel subfamily T member 1 increases expression EXP Mercaptopurine results in increased expression of KCNT1 mRNA CTD PMID:23358152 NCBI chr 3:8,682,964...8,736,615
Ensembl chr 3:8,682,113...8,736,667 		JBrowse link
G Kif20a kinesin family member 20A decreases expression EXP Mercaptopurine results in decreased expression of KIF20A mRNA CTD PMID:23358152 NCBI chr18:26,230,294...26,238,780
Ensembl chr18:26,230,230...26,238,780 		JBrowse link
G Kif23 kinesin family member 23 decreases expression EXP Mercaptopurine results in decreased expression of KIF23 mRNA CTD PMID:23358152 NCBI chr 8:62,397,908...62,425,162
Ensembl chr 8:62,397,948...62,425,072 		JBrowse link
G Klhl40 kelch-like family member 40 increases expression EXP Mercaptopurine results in increased expression of KLHL40 mRNA CTD PMID:23358152 NCBI chr 8:121,441,285...121,446,801
Ensembl chr 8:121,441,287...121,446,800 		JBrowse link
G Knl1 kinetochore scaffold 1 decreases expression EXP Mercaptopurine results in decreased expression of KNL1 mRNA CTD PMID:23358152 NCBI chr 3:106,029,627...106,091,915
Ensembl chr 3:106,029,661...106,091,915 		JBrowse link
G Krt23 keratin 23 increases expression EXP Mercaptopurine results in increased expression of KRT23 mRNA CTD PMID:23358152 NCBI chr10:84,434,445...84,450,773
Ensembl chr10:84,434,380...84,450,983 		JBrowse link
G L1td1 LINE-1 type transposase domain containing 1 decreases expression EXP Mercaptopurine results in decreased expression of L1TD1 mRNA CTD PMID:23358152 NCBI chr 5:113,373,193...113,386,088
Ensembl chr 5:113,379,870...113,385,730 		JBrowse link
G Larp6 La ribonucleoprotein 6, translational regulator increases expression EXP Mercaptopurine results in increased expression of LARP6 mRNA CTD PMID:23358152 NCBI chr 8:61,183,744...61,205,548
Ensembl chr 8:61,184,116...61,205,535 		JBrowse link
G Lipm lipase, family member M increases expression EXP Mercaptopurine results in increased expression of LIPM mRNA CTD PMID:23358152 NCBI chr 1:231,618,145...231,637,599
Ensembl chr 1:231,618,284...231,637,410 		JBrowse link
G Lum lumican decreases expression EXP Mercaptopurine results in decreased expression of LUM mRNA CTD PMID:23358152 NCBI chr 7:32,358,990...32,365,794
Ensembl chr 7:32,358,614...32,365,793 		JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 decreases phosphorylation ISO Mercaptopurine results in decreased phosphorylation of MAP2K1 protein CTD PMID:12697733 NCBI chr 8:64,683,449...64,754,900
Ensembl chr 8:64,683,449...64,755,147 		JBrowse link
G Mcpt10 mast cell protease 10 increases expression EXP Mercaptopurine results in increased expression of MCPT10 mRNA CTD PMID:23358152 NCBI chr15:29,915,483...29,918,540
Ensembl chr15:29,915,483...29,918,511 		JBrowse link
G Mcpt8l2 mast cell protease 8-like 2 increases expression EXP Mercaptopurine results in increased expression of MCPT1L2 mRNA; Mercaptopurine results in increased expression of MCPT8L2 mRNA CTD PMID:23358152
G Mcpt8l3 mast cell protease 8-like 3 increases expression EXP Mercaptopurine results in increased expression of MCPT8L3 mRNA CTD PMID:23358152
G Meox2 mesenchyme homeobox 2 decreases expression EXP Mercaptopurine results in decreased expression of MEOX2 mRNA CTD PMID:23358152 NCBI chr 6:53,856,760...53,917,467
Ensembl chr 6:53,856,758...53,917,467 		JBrowse link
G Mest mesoderm specific transcript decreases expression EXP Mercaptopurine results in decreased expression of MEST mRNA CTD PMID:23358152 NCBI chr 4:59,354,445...59,364,919
Ensembl chr 4:59,354,447...59,366,145 		JBrowse link
G Mfap3l microfibril associated protein 3 like increases expression EXP Mercaptopurine results in increased expression of MFAP3L mRNA CTD PMID:23358152 NCBI chr16:29,411,643...29,454,665
Ensembl chr16:29,415,849...29,430,863 		JBrowse link
G Mir10b microRNA 10b increases expression EXP Mercaptopurine results in increased expression of MIR10B mRNA CTD PMID:23358152 NCBI chr 3:59,628,438...59,628,546
Ensembl chr 3:59,628,438...59,628,546 		JBrowse link
G Mir142 microRNA 142 decreases expression EXP Mercaptopurine results in decreased expression of MIR142 mRNA CTD PMID:23358152 NCBI chr10:72,557,864...72,557,950
Ensembl chr10:72,557,857...72,557,967 		JBrowse link
G Mir144 microRNA 144 decreases expression EXP Mercaptopurine results in decreased expression of MIR144 mRNA CTD PMID:23358152 NCBI chr10:62,961,348...62,961,430
Ensembl chr10:62,961,348...62,961,430 		JBrowse link
G Mir146b microRNA 146b increases expression EXP Mercaptopurine results in increased expression of MIR146B mRNA CTD PMID:23358152 NCBI chr 1:245,203,438...245,203,525
Ensembl chr 1:245,203,438...245,203,525 		JBrowse link
G Mir195 microRNA 195 increases expression EXP Mercaptopurine results in increased expression of MIR195 mRNA CTD PMID:23358152 NCBI chr10:54,951,838...54,951,924
Ensembl chr10:54,951,838...54,951,924 		JBrowse link
G Mir196b microRNA 196b increases expression EXP Mercaptopurine results in increased expression of MIR196B mRNA CTD PMID:23358152 NCBI chr 4:81,330,487...81,330,571
Ensembl chr 4:81,330,487...81,330,571 		JBrowse link
G Mir21 microRNA 21 increases expression EXP Mercaptopurine results in increased expression of MIR21 mRNA CTD PMID:23358152 NCBI chr10:71,405,257...71,405,348
Ensembl chr10:71,405,257...71,405,348 		JBrowse link
G Mir23a microRNA 23a increases expression EXP Mercaptopurine results in increased expression of MIR23A mRNA CTD PMID:23358152 NCBI chr19:23,954,997...23,955,071
Ensembl chr19:23,954,997...23,955,071 		JBrowse link
G Mir29a microRNA 29a increases expression EXP Mercaptopurine results in increased expression of MIR29A mRNA CTD PMID:23358152 NCBI chr 4:59,650,608...59,650,695 JBrowse link
G Mir31 microRNA 31 increases expression EXP Mercaptopurine results in increased expression of MIR31 mRNA CTD PMID:23358152 NCBI chr 5:103,599,038...103,599,143 JBrowse link
G Mir345 microRNA 345 increases expression EXP Mercaptopurine results in increased expression of MIR345 mRNA CTD PMID:23358152 NCBI chr 6:127,754,027...127,754,122
Ensembl chr 6:127,754,027...127,754,122 		JBrowse link
G Mir34a microRNA 34a increases expression EXP Mercaptopurine results in increased expression of MIR34A mRNA CTD PMID:23358152 NCBI chr 5:160,533,002...160,533,103
Ensembl chr 5:160,533,002...160,533,103 		JBrowse link
G Mir451a microRNA 451a decreases expression EXP Mercaptopurine results in decreased expression of MIR451A mRNA CTD PMID:23358152 NCBI chr10:62,961,520...62,961,591
Ensembl chr10:62,961,520...62,961,591 		JBrowse link
G Mir497 microRNA 497 increases expression EXP Mercaptopurine results in increased expression of MIR497 mRNA CTD PMID:23358152 NCBI chr10:54,951,514...54,951,582
Ensembl chr10:54,951,505...54,951,584 		JBrowse link
G Mirlet7b microRNA let-7b increases expression EXP Mercaptopurine results in increased expression of MIRLET7B mRNA CTD PMID:23358152 NCBI chr 7:116,804,186...116,804,270
Ensembl chr 7:116,804,186...116,804,270 		JBrowse link
G Mmp10 matrix metallopeptidase 10 increases expression EXP Mercaptopurine results in increased expression of MMP10 mRNA CTD PMID:23358152 NCBI chr 8:4,689,840...4,697,748
Ensembl chr 8:4,689,840...4,697,748 		JBrowse link
G Mmp7 matrix metallopeptidase 7 increases expression EXP Mercaptopurine results in increased expression of MMP7 mRNA CTD PMID:23358152 NCBI chr 8:4,848,186...4,855,908
Ensembl chr 8:4,848,186...4,855,902 		JBrowse link
G Mocos molybdenum cofactor sulfurase decreases oxidation
multiple interactions		 ISO MOCOS gene SNP results in decreased oxidation of Mercaptopurine
[MOCOS gene SNP results in decreased oxidation of Mercaptopurine] which results in decreased chemical synthesis of 6-thiouric acid; [MOCOS gene SNP results in decreased oxidation of Mercaptopurine] which results in decreased chemical synthesis of 6-thioxanthine; [MOCOS gene SNP results in decreased oxidation of Mercaptopurine] which results in increased chemical synthesis of Thioguanine		 CTD PMID:29935280 NCBI chr18:15,931,659...15,977,415
Ensembl chr18:15,931,654...15,977,187 		JBrowse link
G Msx2 msh homeobox 2 decreases expression EXP Mercaptopurine results in decreased expression of MSX2 mRNA CTD PMID:23358152 NCBI chr17:11,097,214...11,102,879
Ensembl chr17:11,097,103...11,102,879 		JBrowse link
G Mt2A metallothionein 2A increases expression EXP Mercaptopurine results in increased expression of MT2A mRNA CTD PMID:23358152 NCBI chr19:10,832,009...10,832,783
Ensembl chr19:10,832,002...10,832,784 		JBrowse link
G Mt3 metallothionein 3 increases expression EXP Mercaptopurine results in increased expression of MT3 mRNA CTD PMID:23358152 NCBI chr19:10,848,754...10,850,158
Ensembl chr19:10,848,755...10,850,158 		JBrowse link
G Mvp major vault protein decreases response to substance ISO MVP results in decreased susceptibility to Mercaptopurine CTD PMID:19232821 NCBI chr 1:181,594,734...181,622,336
Ensembl chr 1:181,594,734...181,622,380 		JBrowse link
G Myh6 myosin heavy chain 6 decreases expression EXP Mercaptopurine results in decreased expression of MYH6 mRNA CTD PMID:23358152 NCBI chr15:28,418,120...28,442,316
Ensembl chr15:28,417,616...28,441,720 		JBrowse link
G Myl7 myosin light chain 7 increases expression EXP Mercaptopurine results in increased expression of MYL7 mRNA CTD PMID:23358152 NCBI chr14:80,780,684...80,783,259
Ensembl chr14:80,779,776...80,783,244 		JBrowse link
G Myo16 myosin XVI increases expression EXP Mercaptopurine results in increased expression of MYO16 mRNA CTD PMID:23358152 NCBI chr16:78,884,405...79,364,445
Ensembl chr16:78,884,406...79,248,388 		JBrowse link
G Nasp nuclear autoantigenic sperm protein decreases expression EXP Mercaptopurine results in decreased expression of NASP mRNA CTD PMID:23358152 NCBI chr 5:130,057,363...130,083,003
Ensembl chr 5:130,057,363...130,082,928 		JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions ISO Mercaptopurine inhibits the reaction [CD28 protein results in increased activity of [NFKB1 protein binds to RELA protein]] CTD PMID:12697733 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404 		JBrowse link
G Nr4a2 nuclear receptor subfamily 4, group A, member 2 increases expression
multiple interactions		 EXP Mercaptopurine results in increased expression of NR4A2 mRNA
[GW 1929 co-treated with Mercaptopurine] results in increased expression of NR4A2 mRNA; [GW 1929 co-treated with Mercaptopurine] results in increased expression of NR4A2 protein; Mercaptopurine results in increased expression of and affects the localization of NR4A2 protein		 CTD PMID:27435855 NCBI chr 3:41,689,847...41,707,036
Ensembl chr 3:41,689,851...41,697,877 		JBrowse link
G Ntf3 neurotrophin 3 increases expression EXP Mercaptopurine results in increased expression of NTF3 mRNA CTD PMID:23358152 NCBI chr 4:158,914,984...158,984,453
Ensembl chr 4:158,914,957...158,984,596 		JBrowse link
G Nudt15 nudix hydrolase 15 increases response to substance ISO NUDT15 gene SNP results in increased susceptibility to Mercaptopurine CTD PMID:25108385 NCBI chr15:48,707,776...48,713,847
Ensembl chr15:48,709,700...48,747,363 		JBrowse link
G Ogn osteoglycin decreases expression EXP Mercaptopurine results in decreased expression of OGN mRNA CTD PMID:23358152 NCBI chr17:15,032,069...15,052,626
Ensembl chr17:15,032,069...15,052,739 		JBrowse link
G Olah oleoyl-ACP hydrolase increases expression EXP Mercaptopurine results in increased expression of OLAH mRNA CTD PMID:23358152 NCBI chr17:74,877,651...74,902,517
Ensembl chr17:74,877,655...74,902,518 		JBrowse link
G Orm1 orosomucoid 1 increases expression EXP Mercaptopurine results in increased expression of ORM1 mRNA CTD PMID:23358152 NCBI chr 5:76,766,637...76,776,149
Ensembl chr 5:76,772,941...76,776,154 		JBrowse link
G Pacsin1 protein kinase C and casein kinase substrate in neurons 1 decreases expression EXP Mercaptopurine results in decreased expression of PACSIN1 mRNA CTD PMID:23358152 NCBI chr20:5,718,134...5,768,064
Ensembl chr20:5,719,857...5,765,313 		JBrowse link
G Pcdh19 protocadherin 19 decreases expression EXP Mercaptopurine results in decreased expression of PCDH19 mRNA CTD PMID:23358152 NCBI chr  X:96,767,686...96,873,477
Ensembl chr  X:96,771,947...96,873,524 		JBrowse link
G Peli2 pellino E3 ubiquitin protein ligase family member 2 increases expression EXP Mercaptopurine results in increased expression of PELI2 mRNA CTD PMID:23358152 NCBI chr15:21,393,262...21,537,737
Ensembl chr15:21,393,262...21,535,106 		JBrowse link
G Penk proenkephalin decreases expression EXP Mercaptopurine results in decreased expression of PENK mRNA CTD PMID:23358152 NCBI chr 5:17,183,799...17,189,160
Ensembl chr 5:17,183,806...17,189,129 		JBrowse link
G Pgr progesterone receptor increases expression EXP Mercaptopurine results in increased expression of PGR mRNA CTD PMID:23358152 NCBI chr 8:6,072,673...6,131,552
Ensembl chr 8:6,072,673...6,131,344 		JBrowse link
G Phactr3 phosphatase and actin regulator 3 increases expression EXP Mercaptopurine results in increased expression of PHACTR3 mRNA CTD PMID:23358152 NCBI chr 3:165,205,247...165,423,692
Ensembl chr 3:165,205,255...165,423,153 		JBrowse link
G Phlda2 pleckstrin homology-like domain, family A, member 2 decreases expression EXP Mercaptopurine results in decreased expression of PHLDA2 mRNA CTD PMID:23358152 NCBI chr 1:198,696,897...198,699,292
Ensembl chr 1:198,696,897...198,697,836 		JBrowse link
G Pi16 peptidase inhibitor 16 increases expression EXP Mercaptopurine results in increased expression of PI16 mRNA CTD PMID:23358152 NCBI chr20:7,376,073...7,385,386
Ensembl chr20:7,376,126...7,385,383 		JBrowse link
G Pimreg PICALM interacting mitotic regulator decreases expression EXP Mercaptopurine results in decreased expression of PIMREG mRNA CTD PMID:23358152 NCBI chr10:56,669,603...56,674,540
Ensembl chr10:56,669,675...56,674,791 		JBrowse link
G Pinlyp phospholipase A2 inhibitor and Ly6/Plaur domain containing increases expression EXP Mercaptopurine results in increased expression of PINLYP mRNA CTD PMID:23358152 NCBI chr 1:80,134,642...80,140,488
Ensembl chr 1:80,134,643...80,139,996 		JBrowse link
G Pla2g10 phospholipase A2, group X decreases expression EXP Mercaptopurine results in decreased expression of PLA2G10 mRNA CTD PMID:23358152 NCBI chr10:1,597,761...1,610,822
Ensembl chr10:1,597,761...1,609,000 		JBrowse link
G Plekhd1 pleckstrin homology and coiled-coil domain containing D1 decreases expression EXP Mercaptopurine results in decreased expression of PLEKHD1 mRNA CTD PMID:23358152 NCBI chr 6:100,340,655...100,371,942
Ensembl chr 6:100,340,655...100,371,941 		JBrowse link
G Prf1 perforin 1 increases expression EXP Mercaptopurine results in increased expression of PRF1 mRNA CTD PMID:23358152 NCBI chr20:29,246,202...29,251,712
Ensembl chr20:29,246,202...29,251,701 		JBrowse link
G Prl5a2 prolactin family 5, subfamily A, member 2 increases expression EXP Mercaptopurine results in increased expression of PRL5A2 mRNA CTD PMID:23358152 NCBI chr17:36,452,712...36,459,054
Ensembl chr17:36,452,718...36,459,054 		JBrowse link
G Prlr prolactin receptor decreases expression EXP Mercaptopurine results in decreased expression of PRLR mRNA CTD PMID:23358152 NCBI chr 2:59,134,147...59,324,719
Ensembl chr 2:59,134,588...59,324,718 		JBrowse link
G Pttg1 PTTG1 regulator of sister chromatid separation, securin decreases expression EXP Mercaptopurine results in decreased expression of PTTG1 mRNA CTD PMID:23358152 NCBI chr10:27,893,466...27,904,965
Ensembl chr10:27,893,689...27,904,837 		JBrowse link
G Rec8 REC8 meiotic recombination protein decreases expression EXP Mercaptopurine results in decreased expression of REC8 mRNA CTD PMID:23358152 NCBI chr15:29,109,862...29,117,327
Ensembl chr15:29,109,863...29,117,326 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions
affects localization		 ISO Mercaptopurine inhibits the reaction [CD28 protein results in increased activity of [NFKB1 protein binds to RELA protein]]
Mercaptopurine affects the localization of RELA protein		 CTD PMID:12697733 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484 		JBrowse link
G Retn resistin increases expression EXP Mercaptopurine results in increased expression of RETN mRNA CTD PMID:23358152 NCBI chr12:1,710,881...1,712,621
Ensembl chr12:1,710,881...1,712,620 		JBrowse link
G Rflnb refilin B decreases expression EXP Mercaptopurine results in decreased expression of RFLNB mRNA CTD PMID:23358152 NCBI chr10:60,893,693...60,899,970
Ensembl chr10:60,893,713...60,899,976 		JBrowse link
G Rgs1 regulator of G-protein signaling 1 increases expression EXP Mercaptopurine results in increased expression of RGS1 mRNA CTD PMID:23358152 NCBI chr13:56,018,546...56,022,889
Ensembl chr13:56,018,554...56,022,984 		JBrowse link
G Rho rhodopsin increases expression EXP Mercaptopurine results in increased expression of RHO mRNA CTD PMID:23358152 NCBI chr 4:148,975,597...148,988,693
Ensembl chr 4:148,980,611...148,985,773 		JBrowse link
G Rrad RRAD, Ras related glycolysis inhibitor and calcium channel regulator decreases expression EXP Mercaptopurine results in decreased expression of RRAD mRNA CTD PMID:23358152 NCBI chr19:354,184...357,424
Ensembl chr19:354,198...357,417 		JBrowse link
G RT1-Ba RT1 class II, locus Ba affects response to substance ISO HLA-DQA1 gene polymorphism affects the susceptibility to Mercaptopurine CTD PMID:25217962 NCBI chr20:4,575,134...4,579,727
Ensembl chr20:4,575,134...4,579,744 		JBrowse link
G RT1-Db1 RT1 class II, locus Db1 decreases expression
affects response to substance		 EXP
ISO		 Mercaptopurine results in decreased expression of RT1-DB1 mRNA
HLA-DRB1 gene polymorphism affects the susceptibility to Mercaptopurine		 CTD PMID:23358152 PMID:25217962 NCBI chr20:4,548,664...4,558,237
Ensembl chr20:4,548,666...4,558,258 		JBrowse link
G Rtl1 retrotransposon-like 1 decreases expression EXP Mercaptopurine results in decreased expression of RTL1 mRNA CTD PMID:23358152 NCBI chr 6:128,543,904...128,549,384
Ensembl chr 6:128,543,939...128,549,182 		JBrowse link
G Rtn4rl1 reticulon 4 receptor-like 1 increases expression EXP Mercaptopurine results in increased expression of RTN4RL1 mRNA CTD PMID:23358152 NCBI chr10:60,043,246...60,116,977
Ensembl chr10:60,043,002...60,116,978 		JBrowse link
G S100a16 S100 calcium binding protein A16 decreases expression EXP Mercaptopurine results in decreased expression of S100A16 mRNA CTD PMID:23358152 NCBI chr 2:176,016,405...176,022,117
Ensembl chr 2:176,016,268...176,022,117 		JBrowse link
G S100b S100 calcium binding protein B increases expression EXP Mercaptopurine results in increased expression of S100B mRNA CTD PMID:23358152 NCBI chr20:12,372,866...12,381,619
Ensembl chr20:12,372,881...12,394,743 		JBrowse link
G S100z S100 calcium binding protein Z decreases expression EXP Mercaptopurine results in decreased expression of S100Z mRNA CTD PMID:23358152 NCBI chr 2:26,737,796...26,753,611
Ensembl chr 2:26,738,776...26,752,390 		JBrowse link
G Satb1 SATB homeobox 1 decreases expression EXP Mercaptopurine results in decreased expression of SATB1 mRNA CTD PMID:23358152 NCBI chr 9:4,677,817...4,773,061
Ensembl chr 9:4,680,920...4,753,251 		JBrowse link
G Sbspon somatomedin B and thrombospondin, type 1 domain containing decreases expression EXP Mercaptopurine results in decreased expression of SBSPON mRNA CTD PMID:23358152 NCBI chr 5:3,402,763...3,433,338
Ensembl chr 5:3,402,648...3,435,420 		JBrowse link
G Scamp5 secretory carrier membrane protein 5 decreases expression EXP Mercaptopurine results in decreased expression of SCAMP5 mRNA CTD PMID:23358152 NCBI chr 8:57,845,831...57,884,516
Ensembl chr 8:57,846,659...57,872,027 		JBrowse link
G Scd stearoyl-CoA desaturase decreases expression EXP Mercaptopurine results in decreased expression of SCD1 mRNA CTD PMID:23358152 NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562 		JBrowse link
G Scg5 secretogranin V increases expression EXP Mercaptopurine results in increased expression of SCG5 mRNA CTD PMID:23358152 NCBI chr 3:100,544,101...100,588,558
Ensembl chr 3:100,544,099...100,588,463 		JBrowse link
G Scube3 signal peptide, CUB domain and EGF like domain containing 3 increases expression EXP Mercaptopurine results in increased expression of SCUBE3 mRNA CTD PMID:23358152 NCBI chr20:6,199,182...6,231,100
Ensembl chr20:6,199,182...6,228,584 		JBrowse link
G Sftpc surfactant protein C increases expression EXP Mercaptopurine results in increased expression of SFTPC mRNA CTD PMID:23358152 NCBI chr15:45,596,565...45,599,615
Ensembl chr15:45,596,574...45,610,777 		JBrowse link
G Shcbp1l SHC binding and spindle associated 1 like increases expression EXP Mercaptopurine results in increased expression of SHCBP1L mRNA CTD PMID:23358152 NCBI chr13:65,568,863...65,599,155
Ensembl chr13:65,568,863...65,599,154 		JBrowse link
G Shisa3 shisa family member 3 increases expression EXP Mercaptopurine results in increased expression of SHISA3 mRNA CTD PMID:23358152 NCBI chr14:40,563,672...40,568,244
Ensembl chr14:40,563,673...40,568,244 		JBrowse link
G Shisa8 shisa family member 8 decreases expression EXP Mercaptopurine results in decreased expression of SHISA8 mRNA CTD PMID:23358152 NCBI chr 7:113,722,408...113,727,858
Ensembl chr 7:113,722,408...113,727,858 		JBrowse link
G Slc22a3 solute carrier family 22 member 3 decreases expression EXP Mercaptopurine results in decreased expression of SLC22A3 mRNA CTD PMID:23358152 NCBI chr 1:48,235,476...48,324,617
Ensembl chr 1:48,235,476...48,324,612 		JBrowse link
G Slc22a8 solute carrier family 22 member 8 increases transport ISO SLC22A8 protein results in increased transport of Mercaptopurine CTD PMID:15100168 NCBI chr 1:205,496,331...205,516,378
Ensembl chr 1:205,498,084...205,517,450 		JBrowse link
G Slc2a2 solute carrier family 2 member 2 decreases expression EXP Mercaptopurine results in decreased expression of SLC2A2 mRNA CTD PMID:23358152 NCBI chr 2:111,609,798...111,639,930
Ensembl chr 2:111,611,774...111,639,933 		JBrowse link
G Slc2a3 solute carrier family 2 member 3 decreases expression EXP Mercaptopurine results in decreased expression of SLC2A3 mRNA CTD PMID:23358152 NCBI chr 4:155,960,944...156,026,000
Ensembl chr 4:155,960,946...156,025,472 		JBrowse link
G Slc35g1 solute carrier family 35, member G1 decreases expression EXP Mercaptopurine results in decreased expression of SLC35G1 mRNA CTD PMID:23358152 NCBI chr 1:236,163,593...236,172,115
Ensembl chr 1:236,163,175...236,170,262 		JBrowse link
G Slc38a5 solute carrier family 38, member 5 decreases expression EXP Mercaptopurine results in decreased expression of SLC38A5 mRNA CTD PMID:23358152 NCBI chr  X:14,213,727...14,222,498
Ensembl chr  X:14,213,729...14,222,498 		JBrowse link
G Slc5a5 solute carrier family 5 member 5 decreases expression EXP Mercaptopurine results in decreased expression of SLC5A5 mRNA CTD PMID:23358152 NCBI chr16:18,546,709...18,556,698
Ensembl chr16:18,546,709...18,556,697 		JBrowse link
G Slc7a14 solute carrier family 7, member 14 decreases expression EXP Mercaptopurine results in decreased expression of SLC7A14 mRNA CTD PMID:23358152 NCBI chr 2:112,065,286...112,171,319
Ensembl chr 2:112,065,286...112,171,313 		JBrowse link
G Slc9a2 solute carrier family 9 member A2 decreases expression EXP Mercaptopurine results in decreased expression of SLC9A2 mRNA CTD PMID:23358152 NCBI chr 9:42,932,001...43,014,447
Ensembl chr 9:42,931,346...43,014,444 		JBrowse link
G Smoc2 SPARC related modular calcium binding 2 decreases expression EXP Mercaptopurine results in decreased expression of SMOC2 mRNA CTD PMID:23358152 NCBI chr 1:55,262,472...55,391,804
Ensembl chr 1:55,262,530...55,391,693 		JBrowse link
G Sncg synuclein, gamma decreases expression EXP Mercaptopurine results in decreased expression of SNCG mRNA CTD PMID:23358152 NCBI chr16:9,700,513...9,705,751
Ensembl chr16:9,700,514...9,705,368 		JBrowse link
G Sod2 superoxide dismutase 2 increases expression ISO Mercaptopurine results in increased expression of SOD2 mRNA CTD PMID:18222062 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189 		JBrowse link
G Sorcs2 sortilin-related VPS10 domain containing receptor 2 increases expression EXP Mercaptopurine results in increased expression of SORCS2 mRNA CTD PMID:23358152 NCBI chr14:74,371,089...74,735,943
Ensembl chr14:74,371,415...74,735,943 		JBrowse link
G Sostdc1 sclerostin domain containing 1 decreases expression EXP Mercaptopurine results in decreased expression of SOSTDC1 mRNA CTD PMID:23358152 NCBI chr 6:53,051,336...53,055,510
Ensembl chr 6:53,051,354...53,055,579 		JBrowse link
G Spink5 serine peptidase inhibitor, Kazal type 5 increases expression EXP Mercaptopurine results in increased expression of SPINK5 mRNA CTD PMID:23358152 NCBI chr18:36,264,452...36,333,143
Ensembl chr18:36,264,452...36,332,185 		JBrowse link
G Spmip11 sperm microtubule inner protein 11 increases expression EXP Mercaptopurine results in increased expression of NPHS1 mRNA CTD PMID:23358152 NCBI chr 7:129,720,950...129,742,485
Ensembl chr 7:129,720,950...129,742,485 		JBrowse link
G Stfa2l2 stefin A2-like 2 increases expression EXP Mercaptopurine results in increased expression of STFA2L2 mRNA CTD PMID:23358152 NCBI chr11:64,498,151...64,500,576
Ensembl chr11:64,498,206...64,500,574 		JBrowse link
G Synm synemin increases expression EXP Mercaptopurine results in increased expression of SYNM mRNA CTD PMID:23358152 NCBI chr 1:121,333,712...121,363,652
Ensembl chr 1:121,333,720...121,363,652 		JBrowse link
G Tac3 tachykinin precursor 3 decreases expression EXP Mercaptopurine results in decreased expression of TAC2 mRNA CTD PMID:23358152 NCBI chr 7:63,562,552...63,569,170
Ensembl chr 7:63,562,552...63,569,170 		JBrowse link
G Teddm3 transmembrane epididymal family member 3 increases expression EXP Mercaptopurine results in increased expression of TEDDM3 mRNA CTD PMID:23358152 NCBI chr11:79,988,984...79,990,143
Ensembl chr11:79,989,077...79,989,961 		JBrowse link
G Testin testin gene increases expression EXP Mercaptopurine results in increased expression of TESTIN mRNA CTD PMID:23358152 NCBI chr17:3,824,222...3,859,385
Ensembl chr17:3,846,899...3,859,385 		JBrowse link
G Tex10 testis expressed 10 decreases expression EXP Mercaptopurine results in decreased expression of TEX10 mRNA CTD PMID:23358152 NCBI chr 5:62,762,230...62,808,373
Ensembl chr 5:62,762,230...62,808,373 		JBrowse link
G Tfcp2l1 transcription factor CP2-like 1 decreases expression EXP Mercaptopurine results in decreased expression of TFCP2L1 mRNA CTD PMID:23358152 NCBI chr13:29,733,813...29,793,870
Ensembl chr13:29,733,840...29,793,870 		JBrowse link
G Tfrc transferrin receptor decreases expression EXP Mercaptopurine results in decreased expression of TFRC mRNA CTD PMID:23358152 NCBI chr11:68,163,413...68,185,257
Ensembl chr11:68,163,413...68,185,257 		JBrowse link
G Th tyrosine hydroxylase multiple interactions EXP [GW 1929 co-treated with Mercaptopurine] inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of TH protein]; Mercaptopurine inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of TH protein] CTD PMID:27435855 NCBI chr 1:198,071,500...198,078,832
Ensembl chr 1:198,071,503...198,109,767 		JBrowse link
G Thbs4 thrombospondin 4 increases expression EXP Mercaptopurine results in increased expression of THBS4 mRNA CTD PMID:23358152 NCBI chr 2:23,983,158...24,025,289
Ensembl chr 2:23,983,158...24,026,313 		JBrowse link
G Them5 thioesterase superfamily member 5 increases expression EXP Mercaptopurine results in increased expression of THEM5 mRNA CTD PMID:23358152 NCBI chr 2:181,980,783...181,986,002
Ensembl chr 2:181,980,783...181,986,002 		JBrowse link
G Tm4sf20 transmembrane 4 L six family member 20 decreases expression EXP Mercaptopurine results in decreased expression of TM4SF20 mRNA CTD PMID:23358152 NCBI chr 9:84,038,715...84,052,615
Ensembl chr 9:84,038,715...84,052,615 		JBrowse link
G Tmcc2 transmembrane and coiled-coil domain family 2 decreases expression EXP Mercaptopurine results in decreased expression of TMCC2 mRNA CTD PMID:23358152 NCBI chr13:43,794,029...43,831,716
Ensembl chr13:43,794,029...43,831,716 		JBrowse link
G Tmem100 transmembrane protein 100 decreases expression EXP Mercaptopurine results in decreased expression of TMEM100 mRNA CTD PMID:23358152 NCBI chr10:74,854,779...74,861,147
Ensembl chr10:74,854,468...74,862,941 		JBrowse link
G Tmprss7 transmembrane serine protease 7 increases expression EXP Mercaptopurine results in increased expression of TMPRSS7 mRNA CTD PMID:23358152 NCBI chr11:55,127,992...55,166,597
Ensembl chr11:55,128,998...55,164,882 		JBrowse link
G Tp53 tumor protein p53 affects activity ISO Mercaptopurine affects the activity of TP53 protein CTD PMID:35435491 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
G Tpmt thiopurine S-methyltransferase affects response to substance
affects metabolic processing		 ISO TPMT gene polymorphism affects the susceptibility to Mercaptopurine
TPMT protein affects the metabolism of Mercaptopurine		 CTD PMID:12509611 PMID:14505127 NCBI chr17:17,644,088...17,662,709
Ensembl chr17:17,644,173...17,662,709 		JBrowse link
G Trh thyrotropin releasing hormone increases expression EXP Mercaptopurine results in increased expression of TRH mRNA CTD PMID:23358152 NCBI chr 4:124,742,111...124,777,094
Ensembl chr 4:124,742,111...124,744,637 		JBrowse link
G Trpv6 transient receptor potential cation channel, subfamily V, member 6 increases expression EXP Mercaptopurine results in increased expression of TRPV6 mRNA CTD PMID:23358152 NCBI chr 4:70,507,347...70,523,013
Ensembl chr 4:70,507,348...70,523,017 		JBrowse link
G Tspan11 tetraspanin 11 decreases expression EXP Mercaptopurine results in decreased expression of TSPAN11 mRNA CTD PMID:23358152 NCBI chr 4:160,738,149...160,805,522
Ensembl chr 4:160,738,404...160,805,520 		JBrowse link
G Tyms thymidylate synthetase affects response to substance ISO TYMS gene polymorphism affects the susceptibility to Mercaptopurine CTD PMID:15713801 NCBI chr 9:113,313,454...113,329,551
Ensembl chr 9:113,313,452...113,329,536 		JBrowse link
G Uba1y ubiquitin-activating enzyme, Chr Y increases expression EXP Mercaptopurine results in increased expression of UBA1Y mRNA CTD PMID:23358152 NCBI chr  Y:457,617...480,306
Ensembl chr  Y:459,843...480,216 		JBrowse link
G Ubd ubiquitin D increases expression EXP Mercaptopurine results in increased expression of UBD mRNA CTD PMID:23358152 NCBI chr20:1,385,487...1,387,438
Ensembl chr20:1,385,864...1,408,639
Ensembl chr20:1,385,864...1,408,639 		JBrowse link
G Vav1 vav guanine nucleotide exchange factor 1 increases expression ISO Mercaptopurine results in increased expression of VAV1 protein CTD PMID:12697733 NCBI chr 9:2,161,985...2,209,951
Ensembl chr 9:2,157,900...2,208,937 		JBrowse link
G Vdr vitamin D receptor affects response to substance ISO VDR gene polymorphism affects the susceptibility to Mercaptopurine CTD PMID:15713801 NCBI chr 7:128,987,981...129,037,677
Ensembl chr 7:128,987,981...129,037,677 		JBrowse link
G Vgf VGF nerve growth factor inducible increases expression EXP Mercaptopurine results in increased expression of VGF mRNA CTD PMID:23358152 NCBI chr12:19,637,313...19,645,123
Ensembl chr12:19,637,320...19,640,341 		JBrowse link
G Vipr2 vasoactive intestinal peptide receptor 2 decreases expression EXP Mercaptopurine results in decreased expression of VIPR2 mRNA CTD PMID:23358152 NCBI chr 6:136,996,664...137,070,599
Ensembl chr 6:137,001,511...137,070,597 		JBrowse link
G Vom2r12 vomeronasal 2 receptor, 12 decreases expression EXP Mercaptopurine results in decreased expression of VOM2R12 mRNA CTD PMID:23358152 NCBI chr 1:62,022,615...62,045,322
Ensembl chr 1:62,022,417...62,179,453 		JBrowse link
G Wfdc1 WAP four-disulfide core domain 1 increases expression EXP Mercaptopurine results in increased expression of WFDC1 mRNA CTD PMID:23358152 NCBI chr19:47,720,191...47,739,121
Ensembl chr19:47,720,423...47,739,108 		JBrowse link
G Wfdc2 WAP four-disulfide core domain 2 decreases expression EXP Mercaptopurine results in decreased expression of WFDC2 mRNA CTD PMID:23358152 NCBI chr 3:153,286,946...153,314,832
Ensembl chr 3:153,286,131...153,292,807 		JBrowse link
G Wnt10b Wnt family member 10B decreases expression EXP Mercaptopurine results in decreased expression of WNT10B mRNA CTD PMID:23358152 NCBI chr 7:129,922,088...129,927,892
Ensembl chr 7:129,922,088...129,927,892 		JBrowse link
G Wnt2b Wnt family member 2B decreases expression EXP Mercaptopurine results in decreased expression of WNT2B mRNA CTD PMID:23358152 NCBI chr 2:192,454,226...192,468,599
Ensembl chr 2:192,453,824...192,470,308 		JBrowse link
G Wt1 WT1 transcription factor increases expression EXP Mercaptopurine results in increased expression of WT1 mRNA CTD PMID:23358152 NCBI chr 3:91,566,540...91,613,653
Ensembl chr 3:91,567,001...91,613,643 		JBrowse link
G Xdh xanthine dehydrogenase increases expression
affects expression		 EXP Mercaptopurine results in increased expression of XDH mRNA
Mercaptopurine affects the expression of XDH mRNA		 CTD PMID:22688000 PMID:23358152 NCBI chr 6:21,530,463...21,592,172
Ensembl chr 6:21,530,113...21,592,268 		JBrowse link
G Xkrx XK related, X-linked decreases expression EXP Mercaptopurine results in decreased expression of XKRX mRNA CTD PMID:23358152 NCBI chr  X:97,341,158...97,353,175
Ensembl chr  X:97,341,152...97,354,759 		JBrowse link
G Zbtb16 zinc finger and BTB domain containing 16 increases expression EXP Mercaptopurine results in increased expression of ZBTB16 mRNA CTD PMID:23358152 NCBI chr 8:48,989,376...49,177,011
Ensembl chr 8:48,994,566...49,177,011 		JBrowse link
G Zeb2 zinc finger E-box binding homeobox 2 increases expression EXP Mercaptopurine results in increased expression of ZEB2 mRNA CTD PMID:23358152 NCBI chr 3:29,214,581...29,344,890
Ensembl chr 3:29,218,301...29,345,157 		JBrowse link
G Zic3 Zic family member 3 decreases expression EXP Mercaptopurine results in decreased expression of ZIC3 mRNA CTD PMID:23358152 NCBI chr  X:136,123,662...136,129,627
Ensembl chr  X:136,124,026...136,134,746 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19874
    role 19844
      biological role 19842
        biochemical role 19549
          antimetabolite 10283
            mercaptopurine 279
              mercaptopurine hydrate 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19874
    subatomic particle 19872
      composite particle 19872
        hadron 19872
          baryon 19872
            nucleon 19872
              atomic nucleus 19872
                atom 19872
                  main group element atom 19811
                    p-block element atom 19811
                      carbon group element atom 19751
                        carbon atom 19748
                          organic molecular entity 19748
                            organic molecule 19700
                              organic cyclic compound 19490
                                organic heterocyclic compound 18868
                                  organic heteropolycyclic compound 18294
                                    organic heterobicyclic compound 17237
                                      imidazopyrimidine 7756
                                        purines 7755
                                          mercaptopurine 279
                                            mercaptopurine hydrate 0
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