Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:citronellol
go back to main search page
Accession:CHEBI:50462 term browser browse the term
Definition:A monoterpenoid that is oct-6-ene substituted by a hydroxy group at position 1 and methyl groups at positions 3 and 7.
Synonyms:exact_synonym: 3,7-dimethyloct-6-en-1-ol
 related_synonym: 2,3-Dihydrogeraniol;   2,6-Dimethyl-2-octen-8-ol;   3,7-Dimethyl-6-octen-1-ol;   Cephrol;   Elenol;   Formula=C10H20O;   InChI=1S/C10H20O/c1-9(2)5-4-6-10(3)7-8-11/h5,10-11H,4,6-8H2,1-3H3;   InChIKey=QMVPMAAFGQKVCJ-UHFFFAOYSA-N;   SMILES=CC(CCO)CCC=C(C)C;   beta-Citronellol
 xref: Beilstein:1362474;   CAS:106-22-9
 xref_mesh: MESH:C007078
 xref: PMID:20964319;   Reaxys:1362474;   Wikipedia:Citronellol


show annotations for term's descendants           Sort by:
citronellol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB1 ATP binding cassette subfamily B member 1 decreases activity
multiple interactions		 EXP citronellol results in decreased activity of ABCB1 protein
[citronellol results in decreased activity of ABCB1 protein] which results in decreased export of Digoxin; citronellol inhibits the reaction [ABCB1 protein results in increased uptake of Digoxin]		 CTD PMID:15890377 PMID:16904803 NCBI chr 7:87,503,017...87,713,295
Ensembl chr 7:87,503,017...87,713,323 		JBrowse link
G CCL3 C-C motif chemokine ligand 3 multiple interactions ISO citronellol inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CCL3 mRNA] CTD PMID:31926054 NCBI chr17:36,088,256...36,090,143
Ensembl chr17:36,088,256...36,090,169 		JBrowse link
G FBP1 fructose-bisphosphatase 1 multiple interactions ISO citronellol inhibits the reaction [Streptozocin results in increased activity of FBP1 protein] CTD PMID:26944432 NCBI chr 9:94,603,133...94,640,263
Ensembl chr 9:94,603,133...94,640,249 		JBrowse link
G G6PC1 glucose-6-phosphatase catalytic subunit 1 multiple interactions ISO citronellol inhibits the reaction [Streptozocin results in increased activity of G6PC1 protein] CTD PMID:26944432 NCBI chr17:42,900,799...42,914,438
Ensembl chr17:42,900,797...42,914,438 		JBrowse link
G G6PD glucose-6-phosphate dehydrogenase multiple interactions ISO citronellol inhibits the reaction [Streptozocin results in decreased activity of G6PD protein] CTD PMID:26944432 NCBI chr  X:154,531,390...154,547,569
Ensembl chr  X:154,517,825...154,547,572 		JBrowse link
G HTR3A 5-hydroxytryptamine receptor 3A decreases activity EXP citronellol results in decreased activity of HTR3A protein CTD PMID:26456648 NCBI chr11:113,975,108...113,990,313
Ensembl chr11:113,975,075...113,990,313 		JBrowse link
G IL10 interleukin 10 multiple interactions ISO citronellol inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of IL10 protein] CTD PMID:31926054 NCBI chr 1:206,767,602...206,772,494
Ensembl chr 1:206,767,602...206,774,541 		JBrowse link
G IL6 interleukin 6 multiple interactions ISO citronellol inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of IL6 protein] CTD PMID:31926054 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002 		JBrowse link
G INS-IGF2 INS-IGF2 readthrough multiple interactions ISO citronellol inhibits the reaction [Streptozocin results in decreased expression of INS1 protein] CTD PMID:26944432 NCBI chr11:2,129,117...2,161,209
Ensembl chr11:2,132,538...2,161,209 		JBrowse link
G NFKBIA NFKB inhibitor alpha multiple interactions ISO citronellol inhibits the reaction [Lipopolysaccharides results in increased degradation of NFKBIA protein]
citronellol inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of NFKBIA mRNA]		 CTD PMID:20506077 PMID:31926054 NCBI chr14:35,401,513...35,404,749
Ensembl chr14:35,401,079...35,404,749 		JBrowse link
G NOS2 nitric oxide synthase 2 decreases expression
multiple interactions		 ISO citronellol results in decreased expression of NOS2 protein
citronellol inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of NOS2 protein]		 CTD PMID:20506077 PMID:31926054 NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529 		JBrowse link
G OR1A1 olfactory receptor family 1 subfamily A member 1 affects binding ISO
EXP		 citronellol binds to OR1A1B protein
citronellol binds to OR1A1 protein		 CTD PMID:17601748 NCBI chr17:3,207,667...3,218,896
Ensembl chr17:3,207,539...3,218,896 		JBrowse link
G OR1A2 olfactory receptor family 1 subfamily A member 2 affects binding EXP citronellol binds to OR1A2 protein CTD PMID:17601748 NCBI chr17:3,197,519...3,198,448
Ensembl chr17:3,197,519...3,198,448 		JBrowse link
G PPARA peroxisome proliferator activated receptor alpha increases activity EXP citronellol results in increased activity of PPARA protein CTD PMID:21597168 NCBI chr22:46,150,526...46,243,756
Ensembl chr22:46,150,521...46,243,755 		JBrowse link
G PPARG peroxisome proliferator activated receptor gamma increases activity
multiple interactions		 EXP citronellol results in increased activity of PPARG protein
citronellol inhibits the reaction [PPARG protein results in increased expression of PTGS2 mRNA]		 CTD PMID:21597168 NCBI chr 3:12,287,368...12,434,344
Ensembl chr 3:12,287,368...12,434,356 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO
EXP		 citronellol inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA]; citronellol inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein]
citronellol inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of PTGS2 protein]
citronellol inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA]; citronellol inhibits the reaction [PPARG protein results in increased expression of PTGS2 mRNA]		 CTD PMID:20506077 PMID:21597168 PMID:31926054 NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922 		JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit multiple interactions ISO citronellol inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of RELA protein] CTD PMID:31926054 NCBI chr11:65,653,601...65,663,857
Ensembl chr11:65,653,599...65,663,090 		JBrowse link
G TNF tumor necrosis factor multiple interactions ISO citronellol inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of TNF protein] CTD PMID:31926054 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336 		JBrowse link
G TRPV1 transient receptor potential cation channel subfamily V member 1 multiple interactions EXP citronellol binds to and results in increased activity of TRPV1 protein CTD PMID:20686244 NCBI chr17:3,565,446...3,609,411
Ensembl chr17:3,565,444...3,609,411 		JBrowse link
citronellol acetate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TRPM8 transient receptor potential cation channel subfamily M member 8 affects activity ISO citronellyl acetate affects the activity of TRPM8 protein CTD PMID:23562495 NCBI chr 2:233,917,373...234,019,522
Ensembl chr 2:233,917,373...234,019,522 		JBrowse link
G TRPV1 transient receptor potential cation channel subfamily V member 1 affects activity ISO citronellyl acetate affects the activity of TRPV1 protein CTD PMID:23562495 NCBI chr17:3,565,446...3,609,411
Ensembl chr17:3,565,444...3,609,411 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 26490
    role 26267
      biological role 26246
        biochemical role 25499
          metabolite 25385
            eukaryotic metabolite 24902
              plant metabolite 21084
                citronellol 20
                  (R)-(+)-citronellol 0
                  (S)-(-)-citronellol 0
                  citronellol acetate 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 26490
    subatomic particle 26466
      composite particle 26466
        hadron 26411
          baryon 26411
            nucleon 26466
              atomic nucleus 26411
                atom 26466
                  main group element atom 26201
                    main group molecular entity 26201
                      s-block molecular entity 25437
                        hydrogen molecular entity 24842
                          hydrides 23059
                            organic hydride 22021
                              organic fundamental parent 22021
                                hydrocarbon 21455
                                  terpene 14695
                                    monoterpene 3957
                                      monoterpenoid 2087
                                        citronellol 20
                                          (R)-(+)-citronellol 0
                                          (S)-(-)-citronellol 0
                                          citronellol acetate 2
paths to the root