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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:1-naphthylamine
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Accession:CHEBI:50450 term browser browse the term
Definition:A naphthylamine that is naphthalene substituted by an amino group at position 1.
Synonyms:exact_synonym: naphthalen-1-amine
 related_synonym: 1-Naphthylamin;   1-aminonaphthalene;   1-naftilamina;   1-naphthalamine;   1-naphthalenamine;   Formula=C10H9N;   InChI=1S/C10H9N/c11-10-7-3-5-8-4-1-2-6-9(8)10/h1-7H,11H2;   InChIKey=RUFPHBVGCFYCNW-UHFFFAOYSA-N;   SMILES=Nc1cccc2ccccc12;   alpha-aminonaphthalene;   alpha-naphthylamine;   naphthalen-1-ylamine
 alt_id: CHEBI:34098;   CHEBI:50449
 xref: Beilstein:386133;   CAS:134-32-7;   Gmelin:165496;   KEGG:C14790
 xref_mesh: MESH:D015057
 xref: PMID:23706116;   PMID:24735928;   Reaxys:386133;   Wikipedia:1-Naphthylamine


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1-naphthylamine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahr aryl hydrocarbon receptor multiple interactions ISO 1-Naphthylamine binds to and results in increased activity of AHR protein CTD PMID:11790108 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568 		JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 decreases expression ISO 1-Naphthylamine results in decreased expression of CYP17A1 mRNA CTD PMID:31100596 NCBI chr 1:245,535,462...245,543,148
Ensembl chr 1:245,535,462...245,541,573 		JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 increases expression ISO 1-Naphthylamine results in increased expression of CYP19A1 mRNA CTD PMID:31100596 NCBI chr 8:54,552,978...54,580,375
Ensembl chr 8:54,553,165...54,580,758 		JBrowse link
G Fam83b family with sequence similarity 83, member B affects response to substance ISO FAM83B gene SNP affects the susceptibility to 1-Naphthylamine CTD PMID:25622337 NCBI chr 8:77,287,351...77,363,795
Ensembl chr 8:77,287,351...77,363,795 		JBrowse link
G Npas3 neuronal PAS domain protein 3 affects response to substance ISO NPAS3 gene SNP affects the susceptibility to 1-Naphthylamine CTD PMID:25622337 NCBI chr 6:70,702,773...71,527,928
Ensembl chr 6:70,703,170...71,524,884 		JBrowse link
G Tmem132d transmembrane protein 132D affects response to substance ISO TMEM132D gene SNP affects the susceptibility to 1-Naphthylamine CTD PMID:25622337 NCBI chr12:28,270,039...28,917,324
Ensembl chr12:28,270,712...28,915,374 		JBrowse link
G Ugt1a9 UDP glucuronosyltransferase family 1 member A9 decreases activity ISO 1-Naphthylamine results in decreased activity of UGT1A9 protein CTD PMID:14744740 NCBI chr 9:88,696,981...88,808,465
Ensembl chr 9:88,713,184...88,808,465 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19874
    role 19844
      biological role 19842
        biochemical role 19549
          metabolite 19537
            xenobiotic metabolite 16158
              human xenobiotic metabolite 15778
                1-naphthylamine 7
                  N-(1-naphthyl)carboxamide + 0
                  N-hydroxynaphthalen-1-amine 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19874
    subatomic particle 19872
      composite particle 19872
        hadron 19872
          baryon 19872
            nucleon 19872
              atomic nucleus 19872
                atom 19872
                  main group element atom 19811
                    main group molecular entity 19811
                      s-block molecular entity 19647
                        hydrogen molecular entity 19628
                          hydrides 19139
                            inorganic hydride 18156
                              pnictogen hydride 18146
                                nitrogen hydride 18059
                                  azane 17866
                                    ammonia 17865
                                      organic amino compound 17865
                                        primary amino compound 9343
                                          primary amine 6361
                                            primary arylamine 3702
                                              naphthylamine 99
                                                1-naphthylamine 7
                                                  N-(1-naphthyl)carboxamide + 0
                                                  N-hydroxynaphthalen-1-amine 0
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