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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:2-hydroxyisobutyric acid
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Accession:CHEBI:50129 term browser browse the term
Definition:A 2-hydroxy monocarboxylic acid that is isobutyric acid bearing a hydroxy substituent at position 2. It is a metabolite of methyl tertiary-butyl ether.
Synonyms:exact_synonym: 2-hydroxy-2-methylpropanoic acid
 related_synonym: 2-Hydroxy-2-methylpropionic acid;   2-Hydroxy-2-methylpropionsaeure;   2-Methyl-2-hydroxypropionsaeure;   2-Methyllactic acid;   2-methyl-2-hydroxypropanoic acid;   Acetonic acid;   Formula=C4H8O3;   HIBA;   Hydroxydimethylacetic acid;   InChI=1S/C4H8O3/c1-4(2,7)3(5)6/h7H,1-2H3,(H,5,6);   InChIKey=BWLBGMIXKSTLSX-UHFFFAOYSA-N;   SMILES=CC(C)(O)C(O)=O;   acide 2-hydroxy-2-methylpropanoique;   acido 2-hidroxi-2-metilpropionico;   alpha-hydroxy-alpha-methylpropanoic acid;   alpha-hydroxy-alpha-methylpropionic acid;   alpha-hydroxyisobutanoic acid;   alpha-hydroxyisobutyric acid
 xref: CAS:594-61-6;   HMDB:HMDB0000729
 xref_mesh: MESH:C008039
 xref: PMID:12563344;   PMID:12775515;   PMID:17190852;   PMID:20184738;   Patent:WO2009135074;   Reaxys:1744739
 cyclic_relationship: is_conjugate_acid_of CHEBI:19641


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2-hydroxyisobutyric acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lepr leptin receptor affects abundance ISO LEPR affects the abundance of 2-hydroxyisobutyric acid CTD PMID:20567778 NCBI chr 5:116,294,409...116,477,904
Ensembl chr 5:116,289,823...116,475,908 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19874
    role 19844
      biological role 19842
        biochemical role 19549
          volatile oil component 7791
            isobutyric acid 3103
              2-hydroxyisobutyric acid 1
                1,30-diacetyltrichagmalin F 0
                30-acetyltrichagmalin F 0
                trichagmalin F + 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19874
    subatomic particle 19872
      composite particle 19872
        hadron 19872
          baryon 19872
            nucleon 19872
              atomic nucleus 19872
                atom 19872
                  main group element atom 19811
                    p-block element atom 19811
                      carbon group element atom 19751
                        carbon atom 19748
                          organic molecular entity 19748
                            heteroorganic entity 19505
                              organochalcogen compound 19268
                                organooxygen compound 19184
                                  carbon oxoacid 18654
                                    carboxylic acid 18651
                                      monocarboxylic acid 18000
                                        fatty acid 16833
                                          short-chain fatty acid 15925
                                            fatty acid 4:0 8229
                                              isobutyric acid 3103
                                                2-hydroxyisobutyric acid 1
                                                  1,30-diacetyltrichagmalin F 0
                                                  30-acetyltrichagmalin F 0
                                                  trichagmalin F + 0
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