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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:estrogen
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Accession:CHEBI:50114 term browser browse the term
Definition:A hormone that stimulates or controls the development and maintenance of female sex characteristics in mammals by binding to oestrogen receptors. The oestrogens are named for their importance in the oestrous cycle. The oestrogens that occur naturally in the body, notably estrone, estradiol, estriol, and estetrol are steroids. Other compounds with oestrogenic activity are produced by plants (phytoestrogens) and fungi (mycoestrogens); synthetic compounds with oestrogenic activity are known as xenoestrogens.
Synonyms:related_synonym: Estrogene;   estrogenes;   estrogenes Hormon;   estrogeno;   estrogenos;   estrogens;   oestrogen;   oestrogene;   oestrogenes;   oestrogens
 xref: Wikipedia:Estrogen



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  • Term paths to the root
    Path 1
    Term Annotations click to browse term
      CHEBI ontology 19878
        role 19848
          biological role 19846
            molecular messenger 18652
              hormone 18474
                sex hormone 18293
                  estrogen 18248
                    (10R,13S,17R)-17-ethynyl-17-hydroxy-13-methyl-1,2,6,7,8,9,10,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-3-one 0
                    (13S)-3-hydroxy-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-one 0
                    (13S,16R,17R)-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,16,17-triol 0
                    (13S,17R)-17-ethynyl-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthrene-3,17-diol 0
                    (13S,17R)-17-hydroxy-13-methyl-17-prop-2-enyl-1,2,6,7,8,14,15,16-octahydrocyclopenta[a]phenanthren-3-one 0
                    (13S,17S)-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,17-diol 0
                    (7R,8S,9S,13S,14R,17S)-13-methyl-7-[9-(4,4,5,5,5-pentafluoropentylsulfinyl)nonyl]-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,17-diol 0
                    (8R,9S,13S,14R)-3-hydroxy-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-one 0
                    (8R,9S,13S,14R,16R,17R)-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,16,17-triol 0
                    (8R,9S,13S,14R,17R)-17-ethynyl-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthrene-3,17-diol 0
                    (8S,13S,14R,17R)-13-ethyl-17-ethynyl-17-hydroxy-1,2,6,7,8,14,15,16-octahydrocyclopenta[a]phenanthren-3-one 0
                    13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,16,17-triol 0
                    13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,17-diol 0
                    13-methyl-7-[9-(4,4,5,5,5-pentafluoropentylsulfinyl)nonyl]-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,17-diol 0
                    16alpha-hydroxyestrone + 0
                    16beta-hydroxyestrone 0
                    17-epiestriol + 0
                    17-ethynyl-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthrene-3,17-diol 0
                    17alpha-estradiol + 1
                    17alpha-ethynylestradiol 3-sulfate 0
                    17beta-estradiol + 11292
                    2-methoxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,17-diol 0
                    3-hydroxy-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-one 0
                    4-hydroxyestrone + 5
                    4-methoxy-17beta-estradiol + 1
                    4-methoxyestrone + 0
                    7alpha-hydroxydehydroepiandrosterone 0
                    7beta-hydroxydehydroepiandrosterone 0
                    Normethandrolone 0
                    estetrol 0
                    estra-1,3,5(10)-trien-3-ol 3
                    estradiol + 11292
                    estriol + 125
                    estriol 3-O-(beta-D-glucuronide) 1
                    estrone + 128
                    gestodene 26
                    mycoestrogen + 736
                    norgestrienone 0
                    oxabolone 0
                    phytoestrogen + 7883
                    xenoestrogen + 18020
    Path 2
    Term Annotations click to browse term
      CHEBI ontology 19878
        role 19848
          biological role 19846
            pharmacological role 19070
              agonist 18590
                hormone 18474
                  sex hormone 18293
                    estrogen 18248
                      (10R,13S,17R)-17-ethynyl-17-hydroxy-13-methyl-1,2,6,7,8,9,10,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-3-one 0
                      (13S)-3-hydroxy-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-one 0
                      (13S,16R,17R)-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,16,17-triol 0
                      (13S,17R)-17-ethynyl-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthrene-3,17-diol 0
                      (13S,17R)-17-hydroxy-13-methyl-17-prop-2-enyl-1,2,6,7,8,14,15,16-octahydrocyclopenta[a]phenanthren-3-one 0
                      (13S,17S)-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,17-diol 0
                      (7R,8S,9S,13S,14R,17S)-13-methyl-7-[9-(4,4,5,5,5-pentafluoropentylsulfinyl)nonyl]-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,17-diol 0
                      (8R,9S,13S,14R)-3-hydroxy-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-one 0
                      (8R,9S,13S,14R,16R,17R)-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,16,17-triol 0
                      (8R,9S,13S,14R,17R)-17-ethynyl-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthrene-3,17-diol 0
                      (8S,13S,14R,17R)-13-ethyl-17-ethynyl-17-hydroxy-1,2,6,7,8,14,15,16-octahydrocyclopenta[a]phenanthren-3-one 0
                      13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,16,17-triol 0
                      13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,17-diol 0
                      13-methyl-7-[9-(4,4,5,5,5-pentafluoropentylsulfinyl)nonyl]-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,17-diol 0
                      16alpha-hydroxyestrone + 0
                      16beta-hydroxyestrone 0
                      17-epiestriol + 0
                      17-ethynyl-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthrene-3,17-diol 0
                      17alpha-estradiol + 1
                      17alpha-ethynylestradiol 3-sulfate 0
                      17beta-estradiol + 11292
                      2-methoxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,17-diol 0
                      3-hydroxy-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-one 0
                      4-hydroxyestrone + 5
                      4-methoxy-17beta-estradiol + 1
                      4-methoxyestrone + 0
                      7alpha-hydroxydehydroepiandrosterone 0
                      7beta-hydroxydehydroepiandrosterone 0
                      Normethandrolone 0
                      estetrol 0
                      estra-1,3,5(10)-trien-3-ol 3
                      estradiol + 11292
                      estriol + 125
                      estriol 3-O-(beta-D-glucuronide) 1
                      estrone + 128
                      gestodene 26
                      mycoestrogen + 736
                      norgestrienone 0
                      oxabolone 0
                      phytoestrogen + 7883
                      xenoestrogen + 18020
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