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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:stilbene oxide
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Accession:CHEBI:50006 term browser browse the term
Definition:An epoxide that has formula C14H12O.
Synonyms:exact_synonym: 2,3-diphenyloxirane
 related_synonym: Formula=C14H12O;   InChI=1S/C14H12O/c1-3-7-11(8-4-1)13-14(15-13)12-9-5-2-6-10-12/h1-10,13-14H;   InChIKey=ARCJQKUWGAZPFX-UHFFFAOYSA-N;   SMILES=O1C(C1c1ccccc1)c1ccccc1
 xref: Beilstein:136650;   CAS:17619-97-5
 xref_mesh: MESH:C025906


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stilbene oxide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc2 ATP binding cassette subfamily C member 2 increases expression EXP stilbene oxide results in increased expression of ABCC2 mRNA; stilbene oxide results in increased expression of ABCC2 protein CTD PMID:12920174 NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238 		JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 increases expression
multiple interactions		 EXP stilbene oxide results in increased expression of ABCC3 mRNA; stilbene oxide results in increased expression of ABCC3 protein
[stilbene oxide results in increased expression of ABCC3 protein] which affects the export of Acetaminophen metabolite		 CTD PMID:12920174 NCBI chr10:79,296,681...79,342,749
Ensembl chr10:79,296,693...79,342,595 		JBrowse link
G Abcc4 ATP binding cassette subfamily C member 4 increases expression EXP stilbene oxide results in increased expression of ABCC4 mRNA CTD PMID:12920174 NCBI chr15:95,541,186...95,774,898
Ensembl chr15:95,542,315...95,774,283 		JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 increases expression EXP stilbene oxide results in increased expression of CYP2B1 mRNA CTD PMID:10945841 NCBI chr 1:81,518,387...81,544,999
Ensembl chr 1:81,518,408...81,542,052 		JBrowse link
G Cyp2b2 cytochrome P450, family 2, subfamily b, polypeptide 2 increases expression EXP stilbene oxide results in increased expression of CYP2B2 mRNA CTD PMID:10945841 NCBI chr 1:81,594,534...81,608,567
Ensembl chr 1:81,594,555...81,608,566 		JBrowse link
G Cyp3a23-3a1 cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 increases expression EXP stilbene oxide results in increased expression of CYP3A23-3A1 mRNA CTD PMID:10945841 NCBI chr12:9,256,159...9,285,020
Ensembl chr12:9,254,475...9,285,030
Ensembl chr12:9,254,475...9,285,030 		JBrowse link
G Ephx1 epoxide hydrolase 1 multiple interactions
increases metabolic processing		 ISO araldite promotes the reaction [EPHX1 protein results in increased metabolism of stilbene oxide analog]; Dieldrin promotes the reaction [EPHX1 protein results in increased metabolism of stilbene oxide]; ethylphenylepoxygeranyl ether promotes the reaction [EPHX1 protein results in increased metabolism of stilbene oxide]; Heptachlor Epoxide promotes the reaction [EPHX1 protein results in increased metabolism of stilbene oxide]; tridiphane promotes the reaction [EPHX1 protein results in increased metabolism of stilbene oxide]
EPHX1 protein results in increased metabolism of stilbene oxide; EPHX1 protein results in increased metabolism of stilbene oxide analog		 CTD PMID:2043152 NCBI chr13:92,714,315...92,744,105
Ensembl chr13:92,714,315...92,790,235 		JBrowse link
G Ephx2 epoxide hydrolase 2 increases metabolic processing
multiple interactions		 ISO EPHX2 protein results in increased metabolism of stilbene oxide; EPHX2 protein results in increased metabolism of stilbene oxide analog
16 alpha,17-epoxyprogesterone inhibits the reaction [EPHX2 protein results in increased metabolism of stilbene oxide analog]; cholesterol alpha-oxide inhibits the reaction [EPHX2 protein results in increased metabolism of stilbene oxide analog]; Dieldrin promotes the reaction [EPHX2 protein results in increased metabolism of stilbene oxide]; ethylphenylepoxygeranyl ether promotes the reaction [EPHX2 protein results in increased metabolism of stilbene oxide]; Heptachlor Epoxide inhibits the reaction [EPHX2 protein results in increased metabolism of stilbene oxide analog]; Heptachlor Epoxide promotes the reaction [EPHX2 protein results in increased metabolism of stilbene oxide]; Lanosterol analog inhibits the reaction [EPHX2 protein results in increased metabolism of stilbene oxide analog]; limonin inhibits the reaction [EPHX2 protein results in increased metabolism of stilbene oxide analog]; nomilin inhibits the reaction [EPHX2 protein results in increased metabolism of stilbene oxide analog]; tridiphane promotes the reaction [EPHX2 protein results in increased metabolism of stilbene oxide analog]; tridiphane promotes the reaction [EPHX2 protein results in increased metabolism of stilbene oxide]		 CTD PMID:2043152 NCBI chr15:40,289,901...40,327,632
Ensembl chr15:40,289,902...40,327,615 		JBrowse link
G Gsta3 glutathione S-transferase alpha 3 increases expression EXP stilbene oxide results in increased expression of GSTA3 protein CTD PMID:9794803 NCBI chr 9:23,658,574...23,684,240
Ensembl chr 9:23,658,574...23,684,240 		JBrowse link
G Gsta4 glutathione S-transferase alpha 4 increases expression EXP stilbene oxide results in increased expression of GSTA4 protein CTD PMID:9794803 NCBI chr 8:79,066,967...79,084,193
Ensembl chr 8:79,066,934...79,084,182 		JBrowse link
G Gsta5 glutathione S-transferase alpha 5 increases expression EXP stilbene oxide results in increased expression of GSTA5 protein CTD PMID:9794803 NCBI chr 8:79,105,561...79,117,472
Ensembl chr 8:79,105,661...79,117,472 		JBrowse link
G Gstm5 glutathione S-transferase, mu 5 increases expression EXP stilbene oxide results in increased expression of GSTM3 protein CTD PMID:9794803 NCBI chr 2:195,531,599...195,534,562
Ensembl chr 2:195,531,495...195,534,553 		JBrowse link
G Gstp1 glutathione S-transferase pi 1 increases expression EXP stilbene oxide results in increased expression of GSTP1 protein CTD PMID:9794803 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226 		JBrowse link
G Gstt1 glutathione S-transferase theta 1 increases expression EXP stilbene oxide results in increased expression of GSTT1 protein CTD PMID:9794803 NCBI chr20:12,856,613...12,873,586
Ensembl chr20:12,856,669...12,873,585 		JBrowse link
G Gstz1 glutathione S-transferase zeta 1 affects metabolic processing ISO GSTZ1 protein affects the metabolism of stilbene oxide CTD PMID:1846734 NCBI chr 6:106,794,594...106,805,284
Ensembl chr 6:106,794,074...106,805,284 		JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions ISO stilbene oxide binds to and results in increased activity of NR1I2 protein CTD PMID:20869355 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658 		JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 increases expression ISO stilbene oxide results in increased expression of NR1I3 mRNA CTD PMID:31170421 NCBI chr13:83,632,940...83,638,193
Ensembl chr13:83,632,899...83,637,906 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19874
    chemical entity 19872
      molecular entity 19872
        main group molecular entity 19811
          gas molecular entity 18464
            oxirane 11283
              epoxide 11282
                stilbene oxide 17
                  cis-stilbene oxide 0
                  trans-stilbene oxide + 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19874
    subatomic particle 19872
      composite particle 19872
        hadron 19872
          baryon 19872
            nucleon 19872
              atomic nucleus 19872
                atom 19872
                  main group element atom 19811
                    p-block element atom 19811
                      carbon group element atom 19751
                        carbon atom 19748
                          organic molecular entity 19748
                            organic molecule 19700
                              organic cyclic compound 19490
                                organic heterocyclic compound 18868
                                  organic heteromonocyclic compound 17791
                                    saturated organic heteromonocyclic parent 11302
                                      oxirane 11283
                                        epoxide 11282
                                          stilbene oxide 17
                                            cis-stilbene oxide 0
                                            trans-stilbene oxide + 0
paths to the root