|
|
| G
|
A1cf
|
APOBEC1 complementation factor
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to A1CF protein]
|
CTD |
PMID:26598702 |
|
NCBI chr 1:239,149,436...239,242,460
Ensembl chr 1:239,149,493...239,236,817
|
|
| G
|
A2m
|
alpha-2-macroglobulin
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of A2M protein
|
CTD |
PMID:30093655 |
|
NCBI chr 4:156,570,163...156,619,870
Ensembl chr 4:156,569,860...156,619,868
|
|
| G
|
A2ml1
|
alpha-2-macroglobulin-like 1
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of OVOS2P mRNA
|
CTD |
PMID:26705709 |
|
NCBI chr 4:163,501,210...163,543,419
Ensembl chr 4:163,501,585...163,543,506
|
|
| G
|
Aaas
|
aladin WD repeat nucleoporin
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of AAAS mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr 7:135,342,901...135,362,545
Ensembl chr 7:135,342,901...135,362,545
|
|
| G
|
Aamp
|
angio-associated, migratory cell protein
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to AAMP protein]
|
CTD |
PMID:26598702 |
|
NCBI chr 9:83,312,519...83,318,325
Ensembl chr 9:83,312,519...83,318,325
|
|
| G
|
Aars1
|
alanyl-tRNA synthetase 1
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of AARS1 protein
|
CTD |
PMID:19364129 |
|
NCBI chr19:55,906,694...55,930,499
Ensembl chr19:55,906,702...55,930,497
|
|
| G
|
Abat
|
4-aminobutyrate aminotransferase
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of ABAT mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr10:7,503,351...7,599,474
Ensembl chr10:7,492,022...7,599,474
|
|
| G
|
Abca1
|
ATP binding cassette subfamily A member 1
|
increases expression decreases expression multiple interactions
|
ISO
|
Arsenic Trioxide results in increased expression of ABCA1 mRNA Arsenic Trioxide results in decreased expression of ABCA1 mRNA; Arsenic Trioxide results in decreased expression of ABCA1 protein Arsenic Trioxide inhibits the reaction [[Alitretinoin co-treated with 22-hydroxycholesterol] results in increased expression of ABCA1 mRNA]; Arsenic Trioxide inhibits the reaction [[Alitretinoin co-treated with 22-hydroxycholesterol] results in increased expression of ABCA1 protein]
|
CTD |
PMID:16184197 PMID:20339114 PMID:20458559 PMID:25424538 |
|
NCBI chr 5:72,473,676...72,596,563
Ensembl chr 5:72,473,676...72,596,473
|
|
| G
|
Abca3
|
ATP binding cassette subfamily A member 3
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of ABCA3 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr10:13,886,948...13,944,286
Ensembl chr10:13,887,083...13,944,285
|
|
| G
|
Abca9
|
ATP binding cassette subfamily A member 9
|
increases expression affects expression
|
ISO
|
Arsenic Trioxide results in increased expression of ABCA9 mRNA Arsenic Trioxide affects the expression of ABCA10 mRNA
|
CTD |
PMID:20458559 PMID:39716349 |
|
NCBI chr10:95,577,079...95,638,706
Ensembl chr10:95,578,350...95,636,405
|
|
| G
|
Abcb1a
|
ATP binding cassette subfamily B member 1A
|
decreases expression increases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of ABCB1 mRNA; Arsenic Trioxide results in decreased expression of ABCB1 protein Arsenic Trioxide results in increased expression of ABCB1 mRNA; Arsenic Trioxide results in increased expression of ABCB1 protein
|
CTD |
PMID:14642128 PMID:15634520 PMID:15844663 PMID:15979894 PMID:21945491 PMID:22214486 PMID:22959511 PMID:27840903 PMID:29274627 PMID:38758479 More...
|
|
NCBI chr 4:26,312,403...26,488,456
Ensembl chr 4:26,312,409...26,397,135
|
|
| G
|
Abcb4
|
ATP binding cassette subfamily B member 4
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of ABCB4 mRNA
|
CTD |
PMID:27829220 |
|
NCBI chr 4:26,106,895...26,164,440
|
|
| G
|
Abcc1
|
ATP binding cassette subfamily C member 1
|
decreases response to substance increases expression increases secretion increases response to substance increases transport multiple interactions decreases expression
|
ISO
|
ABCC1 protein results in decreased susceptibility to Arsenic Trioxide Arsenic Trioxide results in increased expression of ABCC1 mRNA; Arsenic Trioxide results in increased expression of ABCC1 protein ABCC1 protein results in increased secretion of Arsenic Trioxide ABCC1 gene mutant form results in increased susceptibility to Arsenic Trioxide ABCC1 protein results in increased transport of Arsenic Trioxide [verlukast results in decreased activity of ABCC1 protein] which results in increased susceptibility to Arsenic Trioxide; ABCC1 protein results in decreased uptake of and results in decreased susceptibility to Arsenic Trioxide; Glutathione affects the reaction [ABCC1 protein results in increased secretion of Arsenic Trioxide]; Proanthocyanidins inhibits the reaction [Arsenic Trioxide results in decreased expression of ABCC1 protein]; verlukast inhibits the reaction [ABCC1 protein results in decreased susceptibility to Arsenic Trioxide]; verlukast inhibits the reaction [ABCC1 protein results in decreased uptake of and results in decreased susceptibility to Arsenic Trioxide] Arsenic Trioxide results in decreased expression of ABCC1 mRNA
|
CTD |
PMID:11331074 PMID:12018890 PMID:18633430 PMID:19100828 PMID:20707922 PMID:21783896 PMID:22699396 PMID:23052202 PMID:27736728 PMID:29274627 PMID:30815697 PMID:31355259 PMID:38758479 PMID:39716349 More...
|
|
NCBI chr10:1,022,041...1,162,431
Ensembl chr10:1,038,947...1,162,404
|
|
| G
|
Abcc2
|
ATP binding cassette subfamily C member 2
|
increases expression decreases expression decreases response to substance
|
ISO
|
Arsenic Trioxide results in increased expression of ABCC2 mRNA; Arsenic Trioxide results in increased expression of ABCC2 protein Arsenic Trioxide results in decreased expression of ABCC2 mRNA; Arsenic Trioxide results in decreased expression of ABCC2 protein ABCC2 protein results in decreased susceptibility to Arsenic Trioxide
|
CTD |
PMID:21783896 PMID:21945491 PMID:22214486 PMID:27736728 PMID:38758479 PMID:39716349 More...
|
|
NCBI chr 1:252,613,875...252,672,459
Ensembl chr 1:252,614,017...252,673,471
|
|
| G
|
Abcc3
|
ATP binding cassette subfamily C member 3
|
decreases expression decreases response to substance
|
ISO
|
Arsenic Trioxide results in decreased expression of ABCC3 mRNA ABCC3 protein results in decreased susceptibility to Arsenic Trioxide
|
CTD |
PMID:20707922 PMID:22214486 |
|
NCBI chr10:79,793,571...79,839,528
Ensembl chr10:79,793,583...79,839,494
|
|
| G
|
Abcc4
|
ATP binding cassette subfamily C member 4
|
decreases expression increases expression multiple interactions
|
ISO
|
Arsenic Trioxide results in decreased expression of ABCC4 mRNA Arsenic Trioxide results in increased expression of ABCC4 mRNA [Arsenic Trioxide co-treated with Torsemide] results in decreased expression of ABCC4 mRNA; ABCC4 promotes the reaction [[Arsenic Trioxide co-treated with Torsemide] results in increased abundance of arsenite]; ABCC4 promotes the reaction [[Arsenic Trioxide co-treated with Torsemide] results in increased abundance of Cacodylic Acid]; ABCC4 promotes the reaction [[Arsenic Trioxide co-treated with Torsemide] results in increased abundance of monomethylarsonic acid]
|
CTD |
PMID:19142964 PMID:35676786 PMID:37172335 PMID:38758479 |
|
NCBI chr15:101,948,387...102,182,912
Ensembl chr15:101,949,433...102,181,375
|
|
| G
|
Abcc5
|
ATP binding cassette subfamily C member 5
|
multiple interactions decreases expression increases expression
|
ISO
|
Metformin inhibits the reaction [Arsenic Trioxide results in decreased expression of ABCC5 mRNA] Arsenic Trioxide results in increased expression of ABCC5 mRNA
|
CTD |
PMID:20458559 PMID:29095437 PMID:38758479 |
|
NCBI chr11:93,975,579...94,071,659
Ensembl chr11:93,978,274...94,071,655
|
|
| G
|
Abcc6
|
ATP binding cassette subfamily C member 6
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of ABCC6 mRNA
|
CTD |
PMID:38758479 |
|
NCBI chr 1:105,583,681...105,637,895
Ensembl chr 1:105,583,682...105,637,895
|
|
| G
|
Abcg1
|
ATP binding cassette subfamily G member 1
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of ABCG1 mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr20:9,128,056...9,184,312
Ensembl chr20:9,127,803...9,186,563
|
|
| G
|
Abcg2
|
ATP binding cassette subfamily G member 2
|
increases expression multiple interactions affects expression decreases expression
|
ISO
|
Arsenic Trioxide results in increased expression of ABCG2 mRNA; Arsenic Trioxide results in increased expression of ABCG2 protein prolinedithiocarbamate inhibits the reaction [Arsenic Trioxide results in increased expression of ABCG2 mRNA]; prolinedithiocarbamate inhibits the reaction [Arsenic Trioxide results in increased expression of ABCG2 protein]; TNF protein promotes the reaction [Arsenic Trioxide results in increased expression of ABCG2 mRNA]; TNF protein promotes the reaction [Arsenic Trioxide results in increased expression of ABCG2 protein] Arsenic Trioxide affects the expression of ABCG2 mRNA Arsenic Trioxide results in decreased expression of ABCG2 mRNA; Arsenic Trioxide results in decreased expression of ABCG2 protein
|
CTD |
PMID:17547211 PMID:22214486 PMID:22521957 PMID:29274627 PMID:33634982 |
|
NCBI chr 4:89,006,056...89,132,915
Ensembl chr 4:89,005,969...89,132,493
|
|
| G
|
Abhd1
|
abhydrolase domain containing 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of ABHD1 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 6:31,142,476...31,147,464
Ensembl chr 6:31,142,476...31,147,464
|
|
| G
|
Abhd12b
|
abhydrolase domain containing 12B
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to ABHD12B protein]
|
CTD |
PMID:26598702 |
|
NCBI chr 6:94,404,594...94,432,395
Ensembl chr 6:94,404,594...94,432,395
|
|
| G
|
Abhd3
|
abhydrolase domain containing 3, phospholipase
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of ABHD3 mRNA
|
CTD |
PMID:27829220 |
|
NCBI chr18:1,996,010...2,051,311
Ensembl chr18:1,993,525...2,075,492
|
|
| G
|
Abhd5
|
abhydrolase domain containing 5, lysophosphatidic acid acyltransferase
|
multiple interactions increases expression
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to ABHD5 protein] Arsenic Trioxide results in increased expression of ABHD5 mRNA
|
CTD |
PMID:26598702 PMID:39716349 |
|
NCBI chr 8:130,877,834...130,903,947
Ensembl chr 8:130,877,703...130,903,947
|
|
| G
|
Abi2
|
abl-interactor 2
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of ABI2 mRNA
|
CTD |
PMID:22521957 |
|
NCBI chr 9:69,321,072...69,490,630
Ensembl chr 9:69,321,150...69,490,597
|
|
| G
|
Abl1
|
ABL proto-oncogene 1, non-receptor tyrosine kinase
|
decreases expression multiple interactions affects response to substance
|
ISO
|
Arsenic Trioxide results in decreased expression of ABL1 mRNA; Arsenic Trioxide results in decreased expression of ABL1 protein; Arsenic Trioxide results in decreased expression of ABL1 protein mutant form [Arsenic Trioxide co-treated with Bortezomib] results in decreased expression of ABL1 protein; [nilotinib co-treated with Arsenic Trioxide] results in decreased phosphorylation of ABL1 protein; [Tretinoin co-treated with Arsenic Trioxide] results in increased expression of ABL1 mRNA; Arsenic Trioxide promotes the reaction [ABL1 protein mutant form binds to BECN1 protein]; Arsenic Trioxide promotes the reaction [ABL1 protein mutant form binds to YWHAQ protein]; Arsenic Trioxide results in decreased expression of [BCR protein mutant form binds to ABL1 protein mutant form]; Arsenic Trioxide results in decreased expression of and affects the localization of ABL1 protein mutant form ABL1 protein affects the susceptibility to Arsenic Trioxide
|
CTD |
PMID:10648417 PMID:14633726 PMID:15894607 PMID:17495969 PMID:20458559 PMID:23883479 PMID:24129092 PMID:33070465 More...
|
|
NCBI chr 3:35,377,587...35,480,843
Ensembl chr 3:35,377,391...35,480,846
|
|
| G
|
Ablim1
|
actin-binding LIM protein 1
|
decreases response to substance increases expression
|
ISO
|
ABLIM1 protein results in decreased susceptibility to Arsenic Trioxide Arsenic Trioxide results in increased expression of ABLIM1 mRNA
|
CTD |
PMID:20458559 PMID:20707922 |
|
NCBI chr 1:266,088,868...266,377,169
Ensembl chr 1:266,088,870...266,377,098
|
|
| G
|
Acaa2
|
acetyl-CoA acyltransferase 2
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of ACAA2 mRNA
|
CTD |
PMID:15761015 |
|
NCBI chr18:70,620,310...70,648,417
Ensembl chr18:70,620,110...70,648,420
|
|
| G
|
Acaca
|
acetyl-CoA carboxylase alpha
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of ACACA mRNA
|
CTD |
PMID:30237538 |
|
NCBI chr10:69,511,627...69,773,888
Ensembl chr10:69,511,857...69,773,888
|
|
| G
|
Acacb
|
acetyl-CoA carboxylase beta
|
multiple interactions
|
ISO
|
[Arsenic Trioxide co-treated with Tretinoin] results in increased expression of ACACB mRNA
|
CTD |
PMID:38179723 |
|
NCBI chr12:48,026,394...48,138,214
Ensembl chr12:48,026,394...48,138,214
|
|
| G
|
Acadl
|
acyl-CoA dehydrogenase, long chain
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of ACADL mRNA
|
CTD |
PMID:35676786 |
|
NCBI chr 9:75,783,689...75,822,077
Ensembl chr 9:75,783,689...75,822,164
|
|
| G
|
Acat1
|
acetyl-CoA acetyltransferase 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of ACAT1 mRNA
|
CTD |
PMID:22521957 |
|
NCBI chr 8:62,876,003...62,905,080
Ensembl chr 8:62,876,003...62,905,042
|
|
| G
|
Acat2
|
acetyl-CoA acetyltransferase 2
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of ACAT2 mRNA
|
CTD |
PMID:19128835 |
|
NCBI chr 1:50,100,840...50,118,886
Ensembl chr 1:50,100,817...50,135,095
|
|
| G
|
Ache
|
acetylcholinesterase
|
decreases activity
|
EXP
|
Arsenic Trioxide results in decreased activity of ACHE protein
|
CTD |
PMID:16705804 |
|
NCBI chr12:25,042,882...25,050,608
Ensembl chr12:25,043,461...25,050,410
|
|
| G
|
Ackr1
|
atypical chemokine receptor 1
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of ACKR1 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr13:88,314,735...88,316,354
Ensembl chr13:88,293,188...88,317,807
|
|
| G
|
Acly
|
ATP citrate lyase
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of ACLY mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr10:85,912,402...85,964,605
Ensembl chr10:85,912,402...85,963,631
|
|
| G
|
Aco1
|
aconitase 1
|
increases expression decreases expression
|
ISO
|
Arsenic Trioxide results in increased expression of ACO1 mRNA Arsenic Trioxide results in decreased expression of ACO1 protein
|
CTD |
PMID:19364129 PMID:20458559 |
|
NCBI chr 5:60,055,895...60,111,920
Ensembl chr 5:60,055,866...60,112,600
|
|
| G
|
Aco2
|
aconitase 2
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of ACO2 protein
|
CTD |
PMID:19364129 |
|
NCBI chr 7:115,265,816...115,308,931
Ensembl chr 7:115,265,791...115,308,892
|
|
| G
|
Acot4
|
acyl-CoA thioesterase 4
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of ACOT4 mRNA
|
CTD |
PMID:34108876 |
|
NCBI chr 6:109,399,032...109,405,138
Ensembl chr 6:109,399,578...109,405,138
|
|
| G
|
Acot9
|
acyl-CoA thioesterase 9
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of ACOT9 mRNA
|
CTD |
PMID:22521957 |
|
NCBI chr X:43,922,943...43,973,311
Ensembl chr X:43,914,923...43,973,205
|
|
| G
|
Acox1
|
acyl-CoA oxidase 1
|
multiple interactions increases expression
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to ACOX1 protein] Arsenic Trioxide results in increased expression of ACOX1 mRNA
|
CTD |
PMID:26598702 PMID:35676786 |
|
NCBI chr10:101,905,083...101,930,136
Ensembl chr10:101,905,083...101,930,136
|
|
| G
|
Acox2
|
acyl-CoA oxidase 2
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of ACOX2 mRNA
|
CTD |
PMID:35676786 |
|
NCBI chr15:19,090,820...19,122,392
Ensembl chr15:19,090,926...19,122,392
|
|
| G
|
Acsbg1
|
acyl-CoA synthetase bubblegum family member 1
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to ACSBG1 protein]
|
CTD |
PMID:26598702 |
|
NCBI chr 8:63,887,433...63,943,486
Ensembl chr 8:63,887,435...63,984,178
|
|
| G
|
Acsf3
|
acyl-CoA synthetase family member 3
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of ACSF3 mRNA
|
CTD |
PMID:35676786 |
|
NCBI chr19:67,743,660...67,784,109
Ensembl chr19:67,743,490...67,784,084
|
|
| G
|
Acsl1
|
acyl-CoA synthetase long-chain family member 1
|
multiple interactions increases expression
|
ISO
|
Dasatinib inhibits the reaction [Arsenic Trioxide results in increased expression of ACSL1 mRNA]
|
CTD |
PMID:29266867 |
|
NCBI chr16:52,487,870...52,554,110
Ensembl chr16:52,487,870...52,554,023
|
|
| G
|
Acss2
|
acyl-CoA synthetase short-chain family member 2
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of ACSS2 mRNA
|
CTD |
PMID:27829220 |
|
NCBI chr 3:164,464,124...164,507,607
Ensembl chr 3:164,464,055...164,519,830
|
|
| G
|
Acta2
|
actin alpha 2, smooth muscle
|
multiple interactions increases expression decreases expression
|
ISO EXP
|
3-methyladenine inhibits the reaction [Arsenic Trioxide results in increased expression of ACTA2 protein]; Arsenic Trioxide inhibits the reaction [TGFB1 protein results in increased expression of ACTA2 mRNA]; Arsenic Trioxide inhibits the reaction [TGFB1 protein results in increased expression of ACTA2 protein]; Diosgenin inhibits the reaction [Arsenic Trioxide results in increased expression of ACTA2 protein]; MK-886 inhibits the reaction [Arsenic Trioxide results in increased expression of ACTA2 protein]; NFE2L2 protein affects the reaction [Arsenic Trioxide results in decreased expression of ACTA2 protein]; NR3C1 promotes the reaction [Diosgenin inhibits the reaction [Arsenic Trioxide results in increased expression of ACTA2 protein]]; PML protein affects the reaction [Arsenic Trioxide results in increased expression of ACTA2 protein]; RNF4 protein affects the reaction [Arsenic Trioxide results in increased expression of ACTA2 mRNA]; Taurine inhibits the reaction [Arsenic Trioxide results in increased expression of ACTA2 protein]; UBE2I protein affects the reaction [Arsenic Trioxide results in increased expression of ACTA2 mRNA] Arsenic Trioxide results in increased expression of ACTA2 mRNA; Arsenic Trioxide results in increased expression of ACTA2 protein [Arsenic Trioxide co-treated with Bleomycin] results in decreased expression of ACTA2 mRNA; Taurine inhibits the reaction [Arsenic Trioxide results in increased expression of ACTA2 protein] Arsenic Trioxide results in decreased expression of ACTA2 mRNA; Arsenic Trioxide results in decreased expression of ACTA2 protein [Arsenic Trioxide co-treated with Curcumin] inhibits the reaction [Cisplatin results in increased expression of ACTA2 mRNA]; Arsenic Trioxide inhibits the reaction [Cisplatin results in increased expression of ACTA2 mRNA]; Arsenic Trioxide inhibits the reaction [Cisplatin results in increased expression of ACTA2 protein]; Arsenic Trioxide promotes the reaction [Curcumin inhibits the reaction [Cisplatin results in increased expression of ACTA2 protein]]; Curcumin promotes the reaction [Arsenic Trioxide inhibits the reaction [Cisplatin results in increased expression of ACTA2 protein]]; Diosgenin inhibits the reaction [Arsenic Trioxide results in increased expression of ACTA2 protein]
|
CTD |
PMID:24762191 PMID:30317545 PMID:30677399 PMID:31612257 PMID:32240679 PMID:35276128 PMID:39059093 More...
|
|
NCBI chr 1:241,159,723...241,172,503
Ensembl chr 1:241,159,724...241,172,503
|
|
| G
|
Actb
|
actin, beta
|
decreases expression increases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of ACTB mRNA; Arsenic Trioxide results in decreased expression of ACTB protein Arsenic Trioxide results in increased expression of ACTB mRNA
|
CTD |
PMID:11940349 PMID:20452446 PMID:20458559 |
|
NCBI chr12:16,776,664...16,779,634
Ensembl chr12:16,776,661...16,780,242
|
|
| G
|
Actg1
|
actin, gamma 1
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of ACTG1 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr10:106,118,106...106,120,951
Ensembl chr10:106,118,108...106,120,951
|
|
| G
|
Actg2
|
actin gamma 2, smooth muscle
|
multiple interactions increases expression
|
ISO
|
[Tretinoin co-treated with Arsenic Trioxide] results in increased expression of ACTG2 mRNA Arsenic Trioxide results in increased expression of ACTG2 mRNA
|
CTD |
PMID:15894607 |
|
NCBI chr 4:117,579,513...117,604,379
Ensembl chr 4:117,579,514...117,604,295
|
|
| G
|
Actl6b
|
actin-like 6B
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of ACTL6B mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr12:24,761,660...24,778,193
Ensembl chr12:24,761,693...24,778,151
|
|
| G
|
Actn3
|
actinin alpha 3
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of ACTN3 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 1:211,588,473...211,604,401
Ensembl chr 1:211,588,474...211,604,401
|
|
| G
|
Actr1b
|
actin related protein 1B
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of ACTR1B mRNA
|
CTD |
PMID:27829220 |
|
NCBI chr 9:46,424,677...46,434,341
Ensembl chr 9:46,424,678...46,434,341
|
|
| G
|
Actr3
|
actin related protein 3
|
multiple interactions increases expression
|
ISO
|
[Tretinoin co-treated with Arsenic Trioxide] results in increased expression of ACTR3 protein Arsenic Trioxide results in increased expression of ACTR3 mRNA; Arsenic Trioxide results in increased expression of ACTR3 protein
|
CTD |
PMID:15894607 PMID:22521957 PMID:25419056 |
|
NCBI chr13:39,353,413...39,396,509
Ensembl chr13:39,353,079...39,396,711
|
|
| G
|
Acvrl1
|
activin A receptor like type 1
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of ACVRL1 mRNA
|
CTD |
PMID:18231732 |
|
NCBI chr 7:134,117,917...134,135,306
Ensembl chr 7:134,118,024...134,135,305
|
|
| G
|
Acy1
|
aminoacylase 1
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of ACY1 protein
|
CTD |
PMID:19364129 |
|
NCBI chr 8:115,951,068...115,956,471
Ensembl chr 8:115,951,068...115,956,405
|
|
| G
|
Acyp1
|
acylphosphatase 1
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of ACYP1 mRNA
|
CTD |
PMID:26705709 |
|
NCBI chr 6:110,650,213...110,663,404
Ensembl chr 6:110,650,213...110,663,612
|
|
| G
|
Acyp2
|
acylphosphatase 2
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of ACYP2 mRNA
|
CTD |
PMID:27829220 |
|
NCBI chr14:108,402,837...108,572,367
Ensembl chr14:108,402,544...108,633,318
|
|
| G
|
Adam10
|
ADAM metallopeptidase domain 10
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of ADAM10 mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr 8:80,226,862...80,358,728
Ensembl chr 8:80,226,674...80,361,600
|
|
| G
|
Adam17
|
ADAM metallopeptidase domain 17
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of ADAM17 mRNA
|
CTD |
PMID:35676786 |
|
NCBI chr 6:46,601,583...46,663,690
Ensembl chr 6:46,601,583...46,649,344
|
|
| G
|
Adam19
|
ADAM metallopeptidase domain 19
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of ADAM19 mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr10:30,992,713...31,084,455
Ensembl chr10:30,992,754...31,084,455
|
|
| G
|
Adam24
|
ADAM metallopeptidase domain 24
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of ADAM29 mRNA Arsenic Trioxide results in increased expression of NPIPB11 mRNA
|
CTD |
PMID:20458559 PMID:39716349 |
|
NCBI chr16:58,281,748...58,287,735
Ensembl chr16:58,281,748...58,287,735
|
|
| G
|
Adam8
|
ADAM metallopeptidase domain 8
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of ADAM8 mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr 1:204,206,206...204,218,988
Ensembl chr 1:204,206,199...204,218,485
|
|
| G
|
Adamdec1
|
ADAM-like, decysin 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of ADAMDEC1 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr15:47,076,011...47,097,065
Ensembl chr15:47,076,019...47,097,065
|
|
| G
|
Adamts1
|
ADAM metallopeptidase with thrombospondin type 1 motif, 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of ADAMTS1 mRNA
|
CTD |
PMID:22521957 |
|
NCBI chr11:38,418,565...38,427,384
Ensembl chr11:38,418,101...38,427,390
|
|
| G
|
Adamts15
|
ADAM metallopeptidase with thrombospondin type 1 motif, 15
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of ADAMTS15 mRNA
|
CTD |
PMID:26705709 |
|
NCBI chr 8:37,566,064...37,589,446
Ensembl chr 8:37,566,065...37,589,446
|
|
| G
|
Adamts2
|
ADAM metallopeptidase with thrombospondin type 1 motif, 2
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of ADAMTS2 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr10:35,422,030...35,627,483
Ensembl chr10:35,422,030...35,627,483
|
|
| G
|
Adamts4
|
ADAM metallopeptidase with thrombospondin type 1 motif, 4
|
multiple interactions
|
ISO
|
[Tretinoin co-treated with Arsenic Trioxide] results in decreased expression of ADAMTS4 mRNA
|
CTD |
PMID:15894607 |
|
NCBI chr13:86,203,011...86,212,500
Ensembl chr13:86,202,642...86,212,514
|
|
| G
|
Adamts5
|
ADAM metallopeptidase with thrombospondin type 1 motif, 5
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of ADAMTS5 mRNA
|
CTD |
PMID:25258189 |
|
NCBI chr11:38,486,945...38,533,516
Ensembl chr11:38,486,955...38,533,516
|
|
| G
|
Adamtsl3
|
ADAMTS-like 3
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of ADAMTSL3 mRNA
|
CTD |
PMID:26705709 |
|
NCBI chr 1:145,698,004...146,006,195
Ensembl chr 1:145,698,004...146,006,195
|
|
| G
|
Adap1
|
ArfGAP with dual PH domains 1
|
decreases response to substance
|
ISO
|
ADAP1 protein results in decreased susceptibility to Arsenic Trioxide
|
CTD |
PMID:20707922 |
|
NCBI chr12:20,438,091...20,489,961
Ensembl chr12:20,438,063...20,495,020
|
|
| G
|
Adar
|
adenosine deaminase, RNA-specific
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of ADAR mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 2:177,436,076...177,475,969
Ensembl chr 2:177,436,094...177,475,971
|
|
| G
|
Adat3
|
adenosine deaminase, tRNA-specific 3
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to ADAT3 protein]
|
CTD |
PMID:26598702 |
|
NCBI chr 7:9,759,758...9,761,127
Ensembl chr 7:9,758,671...9,764,582
|
|
| G
|
Adcy1
|
adenylate cyclase 1
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of ADCY1 mRNA
|
CTD |
PMID:24831965 |
|
NCBI chr14:86,125,119...86,234,459
Ensembl chr14:86,124,850...86,261,075
|
|
| G
|
Adcy9
|
adenylate cyclase 9
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of ADCY9 mRNA
|
CTD |
PMID:15761015 |
|
NCBI chr10:11,645,373...11,768,462
Ensembl chr10:11,645,282...11,765,792
|
|
| G
|
Adgre1
|
adhesion G protein-coupled receptor E1
|
increases expression multiple interactions
|
ISO
|
Arsenic Trioxide results in increased expression of ADGRE1 protein Taurine inhibits the reaction [Arsenic Trioxide results in increased expression of ADGRE1 protein]
|
CTD |
PMID:30237538 |
|
NCBI chr 9:2,329,398...2,484,959
Ensembl chr 9:2,329,438...2,484,959
|
|
| G
|
Adgre5
|
adhesion G protein-coupled receptor E5
|
decreases expression increases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of ADGRE5 mRNA Arsenic Trioxide results in increased expression of ADGRE5 mRNA
|
CTD |
PMID:19128835 PMID:39716349 |
|
NCBI chr19:41,302,687...41,332,183
Ensembl chr19:41,303,213...41,324,641
|
|
| G
|
Adgrf5
|
adhesion G protein-coupled receptor F5
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of ADGRF5 mRNA
|
CTD |
PMID:26705709 |
|
NCBI chr 9:25,014,861...25,128,045
Ensembl chr 9:25,018,277...25,121,237
|
|
| G
|
Adgrg2
|
adhesion G protein-coupled receptor G2
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of ADGRG2 mRNA
|
CTD |
PMID:26705709 |
|
NCBI chr X:38,106,067...38,231,286
Ensembl chr X:38,106,067...38,231,331
|
|
| G
|
Adh5
|
alcohol dehydrogenase 5 (class III), chi polypeptide
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to ADH5 protein]
|
CTD |
PMID:26598702 |
|
NCBI chr 2:229,648,557...229,660,964
Ensembl chr 2:229,648,501...229,665,232
|
|
| G
|
Adh6
|
alcohol dehydrogenase 6 (class V)
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of ADH6 mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr 2:229,576,612...229,608,359
Ensembl chr 2:229,576,636...229,607,914
|
|
| G
|
Adipoq
|
adiponectin, C1Q and collagen domain containing
|
decreases expression increases expression multiple interactions
|
ISO
|
Arsenic Trioxide results in decreased expression of ADIPOQ mRNA; Arsenic Trioxide results in decreased expression of ADIPOQ protein Arsenic Trioxide results in increased expression of ADIPOQ mRNA RNF4 protein affects the reaction [Arsenic Trioxide results in increased expression of ADIPOQ mRNA]; UBE2I protein affects the reaction [Arsenic Trioxide results in increased expression of ADIPOQ mRNA]
|
CTD |
PMID:25859628 PMID:32240679 PMID:35676786 |
|
NCBI chr11:91,226,524...91,240,244
Ensembl chr11:91,226,180...91,240,169
|
|
| G
|
Adk
|
adenosine kinase
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of ADK protein
|
CTD |
PMID:25419056 |
|
NCBI chr15:2,912,543...3,295,745
Ensembl chr15:2,912,544...3,295,745
|
|
| G
|
Adm
|
adrenomedullin
|
multiple interactions increases expression decreases expression
|
ISO
|
Bortezomib inhibits the reaction [Arsenic Trioxide results in decreased expression of ADM mRNA] Arsenic Trioxide results in increased expression of ADM mRNA
|
CTD |
PMID:19128835 PMID:20471514 |
|
NCBI chr 1:174,164,178...174,182,372
Ensembl chr 1:174,178,773...174,182,371
|
|
| G
|
Adprs
|
ADP-ribosylserine hydrolase
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of ADPRS mRNA
|
CTD |
PMID:35676786 |
|
NCBI chr 5:143,898,542...143,903,816
Ensembl chr 5:143,898,542...143,903,816
|
|
| G
|
Adra2a
|
adrenoceptor alpha 2A
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of ADRA2A mRNA
|
CTD |
PMID:26705709 |
|
NCBI chr 1:263,066,780...263,069,580
Ensembl chr 1:263,065,278...263,069,871
|
|
| G
|
Adra2b
|
adrenoceptor alpha 2B
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of ADRA2B mRNA
|
CTD |
PMID:19128835 |
|
NCBI chr 3:135,038,481...135,042,527
Ensembl chr 3:135,038,474...135,042,525
|
|
| G
|
Adsl
|
adenylosuccinate lyase
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to ADSL protein]
|
CTD |
PMID:26598702 |
|
NCBI chr 7:114,359,440...114,383,618
Ensembl chr 7:114,359,440...114,384,872
|
|
| G
|
Adss2
|
adenylosuccinate synthase 2
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of ADSS2 protein
|
CTD |
PMID:19364129 |
|
NCBI chr13:92,301,302...92,331,638
Ensembl chr13:92,301,302...92,331,638
|
|
| G
|
Aen
|
apoptosis enhancing nuclease
|
multiple interactions increases expression
|
ISO
|
Metformin inhibits the reaction [Arsenic Trioxide results in increased expression of AEN mRNA]
|
CTD |
PMID:29095437 |
|
NCBI chr 1:142,224,499...142,233,902
Ensembl chr 1:142,224,493...142,233,898
|
|
| G
|
Afap1
|
actin filament associated protein 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of AFAP1 mRNA
|
CTD |
PMID:15761015 |
|
NCBI chr14:78,967,961...79,081,032
Ensembl chr14:78,967,961...79,080,939
|
|
| G
|
Afdn
|
afadin, adherens junction formation factor
|
multiple interactions
|
ISO
|
[Tretinoin co-treated with Arsenic Trioxide] results in decreased expression of AFDN mRNA
|
CTD |
PMID:15894607 |
|
NCBI chr 1:58,041,065...58,170,505
Ensembl chr 1:58,041,641...58,170,505
|
|
| G
|
Aff4
|
ALF transcription elongation factor 4
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of AFF4 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr10:37,998,319...38,080,580
Ensembl chr10:37,999,579...38,080,580
|
|
| G
|
Afp
|
alpha-fetoprotein
|
increases expression decreases expression
|
ISO
|
Arsenic Trioxide results in increased expression of AFP mRNA Arsenic Trioxide results in decreased expression of AFP mRNA; Arsenic Trioxide results in decreased expression of AFP protein
|
CTD |
PMID:23382965 PMID:29767511 PMID:33634982 |
|
NCBI chr14:17,857,584...17,875,645
Ensembl chr14:17,857,584...17,875,649
|
|
| G
|
Aftph
|
aftiphilin
|
decreases response to substance increases expression
|
ISO
|
AFTPH protein results in decreased susceptibility to Arsenic Trioxide Arsenic Trioxide results in increased expression of AFTPH mRNA
|
CTD |
PMID:20458559 PMID:20707922 |
|
NCBI chr14:99,072,761...99,127,006
Ensembl chr14:99,072,761...99,126,727
|
|
| G
|
Agl
|
amylo-alpha-1,6-glucosidase and 4-alpha-glucanotransferase
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of AGL protein Arsenic Trioxide results in increased expression of AGL mRNA
|
CTD |
PMID:25419056 PMID:39716349 |
|
NCBI chr 2:207,389,949...207,445,959
Ensembl chr 2:207,389,949...207,445,724
|
|
| G
|
Ago2
|
argonaute RISC catalytic component 2
|
multiple interactions decreases expression
|
ISO
|
Arsenic Trioxide inhibits the reaction [AGO2 protein binds to SESN2 mRNA] Arsenic Trioxide results in decreased expression of AGO2 protein
|
CTD |
PMID:25419056 PMID:29662624 |
|
NCBI chr 7:106,907,209...106,994,124
Ensembl chr 7:106,918,125...106,993,980
|
|
| G
|
Agpat2
|
1-acylglycerol-3-phosphate O-acyltransferase 2
|
decreases response to substance
|
ISO
|
AGPAT2 protein results in decreased susceptibility to Arsenic Trioxide
|
CTD |
PMID:20707922 |
|
NCBI chr 3:29,814,924...29,826,569
Ensembl chr 3:29,814,924...29,826,581
|
|
| G
|
Agpat4
|
1-acylglycerol-3-phosphate O-acyltransferase 4
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of AGPAT4 mRNA
|
CTD |
PMID:21461292 |
|
NCBI chr 1:51,075,081...51,181,548
Ensembl chr 1:51,075,081...51,180,976
|
|
| G
|
Agpat5
|
1-acylglycerol-3-phosphate O-acyltransferase 5
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of AGPAT5 mRNA
|
CTD |
PMID:26705709 |
|
NCBI chr16:77,641,887...77,688,148
Ensembl chr16:77,641,887...77,688,148
|
|
| G
|
Agps
|
alkylglycerone phosphate synthase
|
multiple interactions decreases expression
|
ISO
|
Arsenic Trioxide inhibits the reaction [Dasatinib results in increased expression of AGPS mRNA] Arsenic Trioxide results in decreased expression of AGPS mRNA
|
CTD |
PMID:29266867 PMID:39716349 |
|
NCBI chr 3:81,154,599...81,253,099
Ensembl chr 3:81,154,604...81,258,277
|
|
| G
|
Agr2
|
anterior gradient 2, protein disulphide isomerase family member
|
decreases response to substance increases expression
|
ISO
|
AGR2 protein results in decreased susceptibility to Arsenic Trioxide Arsenic Trioxide results in increased expression of AGR2 mRNA
|
CTD |
PMID:20707922 PMID:22521957 |
|
NCBI chr 6:58,435,908...58,456,678
Ensembl chr 6:58,435,908...58,456,677
|
|
| G
|
Agrn
|
agrin
|
multiple interactions
|
ISO
|
[Arsenic Trioxide co-treated with apatinib] results in decreased expression of AGRN mRNA
|
CTD |
PMID:39223679 |
|
NCBI chr 5:172,031,528...172,064,429
Ensembl chr 5:172,031,528...172,064,539
|
|
| G
|
Agtpbp1
|
ATP/GTP binding carboxypeptidase 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of AGTPBP1 mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr17:5,092,108...5,244,414
Ensembl chr17:5,126,146...5,244,420
|
|
| G
|
Agtr1a
|
angiotensin II receptor, type 1a
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of AGTR1 mRNA
|
CTD |
PMID:26705709 |
|
NCBI chr17:34,383,397...34,435,523
Ensembl chr17:34,381,467...34,435,660
|
|
| G
|
Ahcy
|
adenosylhomocysteinase
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of AHCY mRNA
|
CTD |
PMID:22521957 |
|
NCBI chr 3:164,029,338...164,044,562
Ensembl chr 3:164,029,338...164,044,587
|
|
| G
|
Ahcyl1
|
adenosylhomocysteinase-like 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of AHCYL1 mRNA
|
CTD |
PMID:22521957 |
|
NCBI chr 2:197,982,335...198,016,770
Ensembl chr 2:197,982,344...198,033,930
|
|
| G
|
Ahcyl2
|
adenosylhomocysteinase-like 2
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to AHCYL2 protein]
|
CTD |
PMID:26598702 |
|
NCBI chr 4:59,348,747...59,498,503
Ensembl chr 4:59,348,217...59,498,502
|
|
| G
|
Ahr
|
aryl hydrocarbon receptor
|
affects localization multiple interactions
|
ISO
|
Arsenic Trioxide affects the localization of AHR protein AHR protein promotes the reaction [Arsenic Trioxide results in increased expression of NQO1 protein]; Arsenic Trioxide results in increased expression of and results in increased localization of AHR protein
|
CTD |
PMID:37423394 PMID:39630573 |
|
NCBI chr 6:57,961,423...57,998,901
Ensembl chr 6:57,961,423...57,998,901
|
|
| G
|
Ahsa2
|
activator of HSP90 ATPase homolog 2
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of AHSA2P mRNA
|
CTD |
PMID:20458559 PMID:39716349 |
|
NCBI chr14:101,677,447...101,688,706
Ensembl chr14:101,677,447...101,686,923
|
|
| G
|
Aicda
|
activation-induced cytidine deaminase
|
multiple interactions decreases expression
|
ISO
|
Imatinib Mesylate promotes the reaction [Arsenic Trioxide results in decreased expression of AICDA protein]
|
CTD |
PMID:21570118 |
|
NCBI chr 4:157,446,120...157,455,958
Ensembl chr 4:157,444,697...157,456,356
|
|
| G
|
Aif1
|
allograft inflammatory factor 1
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of AIF1 mRNA
|
CTD |
PMID:19128835 |
|
NCBI chr20:3,651,435...3,657,341
Ensembl chr20:3,652,243...3,657,339
|
|
| G
|
Aifm1
|
apoptosis inducing factor, mitochondria associated 1
|
multiple interactions affects localization affects expression
|
ISO EXP
|
2-(4-nitrophenyl)-4-(4-fluorophenyl)-5-(4-pyridinyl)-1H-imidazole inhibits the reaction [Arsenic Trioxide affects the localization of AIFM1 protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide affects the localization of AIFM1 protein]; BAX mutant form inhibits the reaction [Arsenic Trioxide affects the localization of AIFM1 protein]; pyrazolanthrone inhibits the reaction [Arsenic Trioxide affects the localization of AIFM1 protein] Arsenic Trioxide affects the expression of AIFM1 protein
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CTD |
PMID:15131059 PMID:18412143 PMID:18618274 |
|
NCBI chr X:132,528,107...132,567,237
Ensembl chr X:132,528,107...132,567,237
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| G
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Akap12
|
A-kinase anchoring protein 12
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of AKAP12 mRNA
|
CTD |
PMID:17547211 PMID:26705709 |
|
NCBI chr 1:43,135,515...43,225,245
Ensembl chr 1:43,199,008...43,225,557
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| G
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Akap13
|
A-kinase anchoring protein 13
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of AKAP13 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 1:138,722,445...139,029,401
Ensembl chr 1:138,724,150...139,029,401
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| G
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Akap3
|
A-kinase anchoring protein 3
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of AKAP3 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 4:161,374,198...161,400,062
Ensembl chr 4:161,374,407...161,400,230
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| G
|
Akap8
|
A-kinase anchoring protein 8
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of AKAP8 mRNA
|
CTD |
PMID:35676786 |
|
NCBI chr 7:11,966,769...11,983,056
Ensembl chr 7:11,966,772...11,982,900
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| G
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Akap8l
|
A-kinase anchoring protein 8 like
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of AKAP8L mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 7:11,983,215...12,012,843
Ensembl chr 7:11,982,721...12,012,811
|
|
| G
|
Akap9
|
A-kinase anchoring protein 9
|
multiple interactions increases expression affects expression
|
ISO
|
[Tretinoin co-treated with Arsenic Trioxide] results in decreased expression of AKAP9 protein Arsenic Trioxide results in increased expression of AKAP9 mRNA Arsenic Trioxide affects the expression of AKAP9 protein
|
CTD |
PMID:15894607 PMID:20458559 |
|
NCBI chr 4:31,011,475...31,147,338
Ensembl chr 4:31,011,475...31,147,338
|
|
| G
|
Akirin2
|
akirin 2
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of AKIRIN2 mRNA
|
CTD |
PMID:22521957 |
|
NCBI chr 5:53,897,792...53,918,873
Ensembl chr 5:53,904,285...53,918,934
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|
| G
|
Akna
|
AT-hook transcription factor
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of AKNA mRNA
|
CTD |
PMID:25258189 |
|
NCBI chr 5:81,792,928...81,839,936
Ensembl chr 5:81,792,929...81,831,528
|
|
| G
|
Akr1a1
|
aldo-keto reductase family 1 member A1
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to AKR1A1 protein]
|
CTD |
PMID:26598702 |
|
NCBI chr 5:135,329,605...135,367,037
Ensembl chr 5:135,329,606...135,367,035
|
|
| G
|
Akr1b1
|
aldo-keto reductase family 1 member B1
|
decreases expression increases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of AKR1B1 mRNA Arsenic Trioxide results in increased expression of AKR1B1 mRNA
|
CTD |
PMID:17547211 PMID:36801614 |
|
NCBI chr 4:63,899,222...63,913,315
Ensembl chr 4:63,899,222...63,913,315
|
|
| G
|
Akr1b10
|
aldo-keto reductase family 1 member B10
|
decreases response to substance
|
ISO
|
AKR1B10 protein results in decreased susceptibility to Arsenic Trioxide
|
CTD |
PMID:20707922 |
|
NCBI chr 4:64,005,632...64,027,860
Ensembl chr 4:64,007,420...64,020,847
|
|
| G
|
Akr1c1
|
aldo-keto reductase family 1, member C1
|
decreases response to substance multiple interactions
|
ISO
|
AKR1C1 protein results in decreased susceptibility to Arsenic Trioxide [Arsenic Trioxide co-treated with Bortezomib] results in increased expression of AKR1C1 mRNA; Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to AKR1C1 protein]
|
CTD |
PMID:20707922 PMID:25913414 PMID:26598702 |
|
NCBI chr17:70,720,397...70,747,285
Ensembl chr17:70,720,398...70,747,247
|
|
| G
|
Akr1c2
|
aldo-keto reductase family 1, member C2
|
increases expression decreases response to substance multiple interactions
|
ISO
|
Arsenic Trioxide results in increased expression of AKR1C2 mRNA AKR1C2 protein results in decreased susceptibility to Arsenic Trioxide Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to AKR1C2 protein]
|
CTD |
PMID:20707922 PMID:21461292 PMID:26598702 PMID:26705709 PMID:39716349 |
|
NCBI chr17:70,669,684...70,717,935
Ensembl chr17:70,669,710...70,685,686
|
|
| G
|
Akr1c3
|
aldo-keto reductase family 1, member C3
|
multiple interactions decreases response to substance increases expression
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to AKR1C3 protein] AKR1C3 protein results in decreased susceptibility to Arsenic Trioxide Arsenic Trioxide results in increased expression of AKR1C3 mRNA
|
CTD |
PMID:19128835 PMID:20707922 PMID:21461292 PMID:26598702 PMID:26705709 PMID:39716349 More...
|
|
NCBI chr17:71,020,884...71,037,779
Ensembl chr17:70,970,900...71,048,438
|
|
| G
|
Akr7a3
|
aldo-keto reductase family 7 member A3
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to AKR7A3 protein]
|
CTD |
PMID:26598702 |
|
NCBI chr 5:156,876,721...156,884,599
Ensembl chr 5:156,874,086...156,885,153
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|
| G
|
Akt1
|
AKT serine/threonine kinase 1
|
increases phosphorylation decreases phosphorylation decreases expression increases activity affects stability multiple interactions decreases response to substance
|
ISO EXP
|
Arsenic Trioxide results in increased phosphorylation of AKT1 protein Arsenic Trioxide results in decreased phosphorylation of AKT1 protein Arsenic Trioxide results in decreased expression of AKT1 mRNA; Arsenic Trioxide results in decreased expression of AKT1 protein Arsenic Trioxide results in increased activity of AKT1 protein Arsenic Trioxide affects the stability of AKT1 protein 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one promotes the reaction [Arsenic Trioxide results in decreased phosphorylation of AKT1 protein]; 4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of AKT1 protein]; [AKT1 protein co-treated with 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole] inhibits the reaction [Arsenic Trioxide results in decreased expression of MCL1 protein]; [Arsenic Trioxide co-treated with IFNA2 protein co-treated with Docosahexaenoic Acids co-treated with Emodin] results in decreased expression of AKT1 protein; [Arsenic Trioxide results in increased expression of BCL2L11 protein] which results in decreased phosphorylation of AKT1 protein; [aspartyl-glutamyl-valyl-aspartal results in decreased activity of CASP3 protein] inhibits the reaction [Arsenic Trioxide results in decreased phosphorylation of AKT1 protein]; [Bortezomib results in decreased activity of CBL protein] promotes the reaction [Arsenic Trioxide results in increased activity of AKT1 protein]; [Sirolimus co-treated with Arsenic Trioxide] results in decreased phosphorylation of AKT1 protein; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in decreased activity of AKT1 protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in decreased phosphorylation of AKT1 protein]; AKT1 mutant form promotes the reaction [Arsenic Trioxide results in increased cleavage of CASP3 protein]; AKT1 mutant form promotes the reaction [Arsenic Trioxide results in increased cleavage of CASP9 protein]; AKT1 protein affects the reaction [Arsenic Trioxide affects the localization of SLC2A1 protein]; AKT1 protein affects the reaction [Arsenic Trioxide results in increased expression of CCND1 protein]; AKT1 protein affects the reaction [Arsenic Trioxide results in increased expression of CDC6 protein]; AKT1 protein inhibits the reaction [Arsenic Trioxide results in decreased phosphorylation of GSK3B protein]; AKT1 protein inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of MAPK1 protein]; AKT1 protein inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of MAPK3 protein]; AKT1 protein promotes the reaction [Arsenic Trioxide results in increased expression of TGIF1 mRNA]; Arsenic Trioxide affects the reaction [temsirolimus results in increased phosphorylation of AKT1 protein]; Arsenic Trioxide inhibits the reaction [AKT1 protein binds to MAPK8IP1 protein]; Arsenic Trioxide inhibits the reaction [lonidamine results in increased phosphorylation of AKT1 protein]; Arsenic Trioxide inhibits the reaction [Sirolimus results in increased phosphorylation of AKT1 protein]; Arsenic Trioxide inhibits the reaction [TGFB1 protein results in increased phosphorylation of AKT1 protein]; Arsenic Trioxide promotes the reaction [2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in decreased phosphorylation of AKT1 protein]; Arsenic Trioxide promotes the reaction [AKT1 protein binds to PPP2CA protein]; Arsenic Trioxide promotes the reaction [Curcumin results in decreased phosphorylation of AKT1 protein]; Arsenic Trioxide promotes the reaction [tanespimycin results in decreased expression of AKT1 protein]; Arsenic Trioxide promotes the reaction [Tretinoin results in decreased expression of AKT1 protein]; Arsenic Trioxide results in decreased activity of and results in decreased expression of AKT1 protein; Arsenic Trioxide results in decreased phosphorylation of and results in decreased activity of AKT1 protein; Arsenic Trioxide results in increased phosphorylation of and results in increased activity of AKT1 protein; aspartyl-glutamyl-valyl-aspartal inhibits the reaction [Arsenic Trioxide promotes the reaction [AKT1 protein binds to PPP2CA protein]]; benzyloxycarbonyl-valyl-alanyl-aspartic acid inhibits the reaction [Arsenic Trioxide results in decreased expression of AKT1 protein]; Gemcitabine promotes the reaction [Arsenic Trioxide results in decreased phosphorylation of AKT1 protein]; Genistein inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of and results in increased activity of AKT1 protein]; MAPK8 protein affects the reaction [Arsenic Trioxide results in decreased phosphorylation of and results in decreased activity of AKT1 protein]; NSC 680410 promotes the reaction [Arsenic Trioxide results in decreased phosphorylation of AKT1 protein]; Okadaic Acid inhibits the reaction [Arsenic Trioxide promotes the reaction [AKT1 protein binds to PPP2CA protein]]; Okadaic Acid inhibits the reaction [Arsenic Trioxide results in decreased phosphorylation of AKT1 protein]; Palmitic Acid inhibits the reaction [Arsenic Trioxide results in decreased phosphorylation of AKT1 protein]; pyrazolanthrone inhibits the reaction [Arsenic Trioxide results in decreased phosphorylation of and results in decreased activity of AKT1 protein]; Rosiglitazone inhibits the reaction [Arsenic Trioxide results in decreased phosphorylation of AKT1 protein]; setanaxib inhibits the reaction [Arsenic Trioxide results in decreased phosphorylation of AKT1 protein]; tanespimycin promotes the reaction [Arsenic Trioxide results in decreased expression of AKT1 protein]; Taurine inhibits the reaction [Arsenic Trioxide results in decreased phosphorylation of AKT1 protein]; Tretinoin promotes the reaction [Arsenic Trioxide results in decreased expression of AKT1 protein] 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one promotes the reaction [Arsenic Trioxide results in decreased phosphorylation of AKT1 protein]; Arsenic Trioxide inhibits the reaction [AKT1 protein binds to PPARG protein]; Arsenic Trioxide inhibits the reaction [Glycerol results in increased phosphorylation of AKT1 protein]; Arsenic Trioxide promotes the reaction [Reserpine results in decreased phosphorylation of AKT1 protein]; Arsenic Trioxide results in increased expression of and results in increased phosphorylation of AKT1 protein; Genistein inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of AKT1 protein]; Taurine inhibits the reaction [Arsenic Trioxide results in decreased phosphorylation of AKT1 protein] AKT1 protein results in decreased susceptibility to Arsenic Trioxide; AKT1 results in decreased susceptibility to Arsenic Trioxide Arsenic Trioxide results in decreased expression of and results in decreased phosphorylation of AKT1 protein; dapagliflozin inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of AKT1 protein]; Phloretin inhibits the reaction [Arsenic Trioxide results in decreased expression of AKT1 mRNA]; trans-sodium crocetinate inhibits the reaction [Arsenic Trioxide results in decreased expression of and results in decreased phosphorylation of AKT1 protein]
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CTD |
PMID:12168106 PMID:15688020 PMID:15916724 PMID:16115127 PMID:16434995 PMID:16882451 PMID:17077332 PMID:18048359 PMID:18566239 PMID:19457607 PMID:20200477 PMID:20299303 PMID:20458559 PMID:20534739 PMID:20605902 PMID:20657188 PMID:20862710 PMID:21078540 PMID:21594580 PMID:21649584 PMID:21655183 PMID:21889928 PMID:24392034 PMID:24762191 PMID:25449439 PMID:25758096 PMID:25791921 PMID:26114099 PMID:29266867 PMID:30032600 PMID:30093655 PMID:30225639 PMID:30362509 PMID:32305283 PMID:32919218 PMID:33462182 PMID:34037972 PMID:35714947 PMID:36400307 PMID:38070468 More...
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|
NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:137,535,390...137,552,610
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| G
|
Akt2
|
AKT serine/threonine kinase 2
|
decreases response to substance
|
ISO
|
AKT2 protein results in decreased susceptibility to Arsenic Trioxide
|
CTD |
PMID:18048359 |
|
NCBI chr 1:92,004,705...92,061,420
Ensembl chr 1:92,014,859...92,061,420
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|
| G
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Alad
|
aminolevulinate dehydratase
|
multiple interactions decreases expression
|
ISO
|
beta Carotene inhibits the reaction [Arsenic Trioxide results in decreased expression of ALAD protein]
|
CTD |
PMID:25542264 |
|
NCBI chr 5:80,977,562...80,987,901
Ensembl chr 5:80,977,562...80,988,041
|
|
| G
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Alas1
|
5'-aminolevulinate synthase 1
|
increases expression multiple interactions
|
ISO
|
Arsenic Trioxide results in increased expression of ALAS1 mRNA [Tretinoin co-treated with Arsenic Trioxide] results in increased expression of ALAS1 mRNA
|
CTD |
PMID:15725085 PMID:15894607 PMID:29633893 |
|
NCBI chr 8:115,755,238...115,768,642
Ensembl chr 8:115,755,238...115,768,642
|
|
| G
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Alas2
|
5'-aminolevulinate synthase 2
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of ALAS2 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr X:22,890,650...22,914,046
Ensembl chr X:22,890,689...22,914,043
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| G
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Alb
|
albumin
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multiple interactions decreases expression
|
ISO EXP
|
Arsenic Trioxide binds to and affects the folding of ALB protein Arsenic Trioxide results in decreased expression of ALB protein baicalin inhibits the reaction [Arsenic Trioxide results in decreased expression of ALB protein] dapagliflozin inhibits the reaction [Arsenic Trioxide results in decreased expression of ALB protein]
|
CTD |
PMID:25863441 PMID:35088608 PMID:38070468 |
|
NCBI chr14:17,891,564...17,907,043
Ensembl chr14:17,891,582...17,911,865
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|
| G
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Aldh18a1
|
aldehyde dehydrogenase 18 family, member A1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of ALDH18A1 mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr 1:249,325,082...249,357,383
Ensembl chr 1:249,325,082...249,357,383
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|
| G
|
Aldh1a1
|
aldehyde dehydrogenase 1 family, member A1
|
multiple interactions decreases expression
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to ALDH1A1 protein] Arsenic Trioxide results in decreased expression of ALDH1A1 mRNA
|
CTD |
PMID:24061648 PMID:26598702 PMID:29633893 |
|
NCBI chr 1:227,426,939...227,579,497
Ensembl chr 1:227,427,070...227,579,500
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|
| G
|
Aldh1a3
|
aldehyde dehydrogenase 1 family, member A3
|
increases expression multiple interactions decreases expression
|
ISO
|
Arsenic Trioxide results in increased expression of ALDH1A3 protein Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to ALDH1A3 protein] Arsenic Trioxide results in decreased expression of ALDH1A3 mRNA
|
CTD |
PMID:25419056 PMID:26598702 PMID:26705709 |
|
NCBI chr 1:129,392,516...129,436,552
Ensembl chr 1:129,392,516...129,427,777
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|
| G
|
Aldh1b1
|
aldehyde dehydrogenase 1 family, member B1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of ALDH1B1 mRNA
|
CTD |
PMID:22521957 |
|
NCBI chr 5:64,859,000...64,864,008
Ensembl chr 5:64,858,934...64,864,365
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|
| G
|
Aldh3a1
|
aldehyde dehydrogenase 3 family, member A1
|
multiple interactions decreases response to substance decreases expression increases expression
|
ISO
|
ALDH3A1 protein inhibits the reaction [PML mutant form results in increased susceptibility to Arsenic Trioxide] ALDH3A1 protein results in decreased susceptibility to Arsenic Trioxide Arsenic Trioxide results in decreased expression of ALDH3A1 mRNA Arsenic Trioxide results in increased expression of ALDH3A1 mRNA
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CTD |
PMID:20707922 PMID:26118777 PMID:35676786 PMID:39716349 |
|
NCBI chr10:46,392,464...46,402,151
Ensembl chr10:46,392,411...46,402,151
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|
| G
|
Aldh3a2
|
aldehyde dehydrogenase 3 family, member A2
|
increases expression decreases response to substance
|
ISO
|
Arsenic Trioxide results in increased expression of ALDH3A2 mRNA ALDH3A2 protein results in decreased susceptibility to Arsenic Trioxide
|
CTD |
PMID:20458559 PMID:20707922 |
|
NCBI chr10:46,427,789...46,448,449
Ensembl chr10:46,407,993...46,448,648
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|
| G
|
Aldh3b1
|
aldehyde dehydrogenase 3 family, member B1
|
decreases response to substance
|
ISO
|
ALDH3B1 protein results in decreased susceptibility to Arsenic Trioxide
|
CTD |
PMID:20707922 |
|
NCBI chr 1:210,574,545...210,605,188
Ensembl chr 1:210,573,661...210,610,538
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|
| G
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Aldh4a1
|
aldehyde dehydrogenase 4 family, member A1
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to ALDH4A1 protein]
|
CTD |
PMID:26598702 |
|
NCBI chr 5:157,163,189...157,188,673
Ensembl chr 5:157,162,945...157,188,673
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|
| G
|
Aldh6a1
|
aldehyde dehydrogenase 6 family, member A1
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of ALDH6A1 mRNA
|
CTD |
PMID:17547211 |
|
NCBI chr 6:109,809,092...109,829,725
Ensembl chr 6:109,809,122...109,829,743
|
|
| G
|
Aldh7a1
|
aldehyde dehydrogenase 7 family, member A1
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of ALDH7A1 mRNA
|
CTD |
PMID:26705709 PMID:39716349 |
|
NCBI chr18:52,208,035...52,240,293
Ensembl chr18:52,204,161...52,240,467
|
|
| G
|
Aldh8a1
|
aldehyde dehydrogenase 8 family, member A1
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of ALDH8A1 mRNA
|
CTD |
PMID:25424538 |
|
NCBI chr 1:18,003,507...18,022,952
Ensembl chr 1:18,003,514...18,023,883
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|
| G
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Aldoa
|
aldolase, fructose-bisphosphate A
|
multiple interactions decreases expression
|
ISO
|
[Tretinoin co-treated with Arsenic Trioxide] results in increased expression of ALDOA mRNA Arsenic Trioxide results in decreased expression of ALDOA protein
|
CTD |
PMID:15894607 |
|
NCBI chr 1:190,832,820...190,838,021
Ensembl chr 1:190,832,820...190,838,211
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|
| G
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Aldoc
|
aldolase, fructose-bisphosphate C
|
decreases expression multiple interactions
|
ISO
|
Arsenic Trioxide results in decreased expression of ALDOC mRNA Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to ALDOC protein]
|
CTD |
PMID:15725085 PMID:26598702 |
|
NCBI chr10:63,715,544...63,719,133
Ensembl chr10:63,715,489...63,719,133
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|
| G
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Alg13
|
ALG13, UDP-N-acetylglucosaminyltransferase subunit
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of ALG13 mRNA
|
CTD |
PMID:15761015 |
|
NCBI chr X:112,703,015...112,764,924
Ensembl chr X:112,702,796...112,739,356
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|
| G
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Alkbh4
|
alkB homolog 4, lysine demethylase
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to ALKBH4 protein]
|
CTD |
PMID:26598702 |
|
NCBI chr12:26,160,643...26,166,560
Ensembl chr12:26,160,643...26,166,560
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|
| G
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Alkbh5
|
alkB homolog 5, RNA demethylase
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of ALKBH5 protein
|
CTD |
PMID:35226250 |
|
NCBI chr10:45,844,411...45,865,853
Ensembl chr10:45,843,656...45,869,658
|
|
| G
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Alox15
|
arachidonate 15-lipoxygenase
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of ALOX15 mRNA
|
CTD |
PMID:35676786 PMID:38758479 |
|
NCBI chr10:55,559,060...55,567,535
Ensembl chr10:55,559,061...55,567,723
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|
| G
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Alox5
|
arachidonate 5-lipoxygenase
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of ALOX5 mRNA
|
CTD |
PMID:38758479 |
|
NCBI chr 4:151,203,948...151,251,126
Ensembl chr 4:151,203,949...151,251,126
|
|
| G
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Alox5ap
|
arachidonate 5-lipoxygenase activating protein
|
increases expression decreases expression multiple interactions
|
ISO
|
Arsenic Trioxide results in increased expression of ALOX5AP mRNA Arsenic Trioxide results in decreased expression of ALOX5AP mRNA [Tretinoin co-treated with Arsenic Trioxide] results in increased expression of ALOX5AP mRNA
|
CTD |
PMID:15070760 PMID:15761015 PMID:15894607 PMID:19128835 |
|
NCBI chr12:10,785,254...10,809,295
Ensembl chr12:10,785,257...10,817,038
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|
| G
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Alpk2
|
alpha-kinase 2
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of ALPK2 mRNA
|
CTD |
PMID:35676786 |
|
NCBI chr18:61,045,717...61,161,703
Ensembl chr18:61,045,380...61,175,985
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|
| G
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Alpl
|
alkaline phosphatase, biomineralization associated
|
decreases expression
|
EXP
|
Arsenic Trioxide results in decreased expression of ALPL mRNA
|
CTD |
PMID:22465848 |
|
NCBI chr 5:155,234,770...155,289,785
Ensembl chr 5:155,234,775...155,254,167
|
|
| G
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Alpp
|
alkaline phosphatase, placental
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of ALPP protein
|
CTD |
PMID:30093655 |
|
NCBI chr 9:95,213,763...95,216,509
Ensembl chr 9:95,213,374...95,219,451
|
|
| G
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Als2
|
alsin Rho guanine nucleotide exchange factor ALS2
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of ALS2 mRNA
|
CTD |
PMID:24831965 |
|
NCBI chr 9:68,107,310...68,180,192
Ensembl chr 9:68,107,528...68,179,660
|
|
| G
|
Als2cl
|
ALS2 C-terminal like
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of ALS2CL mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr 8:119,746,498...119,762,824
Ensembl chr 8:119,743,248...119,762,843
|
|
| G
|
Alx4
|
ALX homeobox 4
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of ALX4 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 3:100,067,052...100,103,624
Ensembl chr 3:100,067,052...100,103,624
|
|
| G
|
Amacr
|
alpha-methylacyl-CoA racemase
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of AMACR mRNA
|
CTD |
PMID:26705709 PMID:39716349 |
|
NCBI chr 2:61,673,291...61,685,381
Ensembl chr 2:61,670,475...61,685,379
|
|
| G
|
Ambp
|
alpha-1-microglobulin/bikunin precursor
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of AMBP mRNA
|
CTD |
PMID:27829220 |
|
NCBI chr 5:81,583,621...81,593,938
Ensembl chr 5:81,583,622...81,593,850
|
|
| G
|
Amd1
|
adenosylmethionine decarboxylase 1
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to AMD1 protein]
|
CTD |
PMID:26598702 |
|
NCBI chr20:45,250,289...45,324,939
Ensembl chr20:45,250,289...45,265,982
|
|
| G
|
Amfr
|
autocrine motility factor receptor
|
decreases response to substance
|
ISO
|
AMFR protein results in decreased susceptibility to Arsenic Trioxide
|
CTD |
PMID:20707922 |
|
NCBI chr19:11,002,451...11,038,182
Ensembl chr19:11,002,101...11,038,364
|
|
| G
|
Amot
|
angiomotin
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of AMOT mRNA
|
CTD |
PMID:26705709 |
|
NCBI chr X:113,778,990...113,837,846
Ensembl chr X:113,781,526...113,837,482
|
|
| G
|
Anapc5
|
anaphase-promoting complex subunit 5
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of ANAPC5 mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr12:39,409,519...39,442,518
Ensembl chr12:39,385,399...39,442,762
|
|
| G
|
Angpt1
|
angiopoietin 1
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of ANGPT1 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 7:75,415,959...75,668,696
Ensembl chr 7:75,418,218...75,668,696
|
|
| G
|
Angpt2
|
angiopoietin 2
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of ANGPT2 mRNA
|
CTD |
PMID:20458559 PMID:36801614 |
|
NCBI chr16:77,790,760...77,841,241
Ensembl chr16:77,790,563...77,841,239
|
|
| G
|
Angptl1
|
angiopoietin-like 1
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of ANGPTL1 mRNA
|
CTD |
PMID:26705709 |
|
NCBI chr13:71,463,913...71,531,810
Ensembl chr13:71,511,727...71,531,818
|
|
| G
|
Angptl7
|
angiopoietin like 7
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of ANGPTL7 mRNA
|
CTD |
PMID:35676786 |
|
NCBI chr 5:164,215,223...164,220,408
Ensembl chr 5:164,215,223...164,220,584
|
|
| G
|
Ank3
|
ankyrin 3
|
increases expression decreases expression
|
ISO
|
Arsenic Trioxide results in increased expression of ANK3 mRNA Arsenic Trioxide results in decreased expression of ANK3 mRNA
|
CTD |
PMID:15761015 |
|
NCBI chr20:18,601,307...19,224,790
Ensembl chr20:18,601,826...19,084,879
|
|
| G
|
Ankhd1
|
ankyrin repeat and KH domain containing 1
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to ANKHD1 protein]
|
CTD |
PMID:26598702 |
|
NCBI chr18:28,436,296...28,534,954
Ensembl chr18:28,436,394...28,534,954
|
|
| G
|
Ankib1
|
ankyrin repeat and IBR domain containing 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of ANKIB1 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 4:31,288,393...31,412,500
Ensembl chr 4:31,288,142...31,412,504
|
|
| G
|
Ankrd11
|
ankyrin repeat domain containing 11
|
increases expression decreases expression
|
ISO
|
Arsenic Trioxide results in increased expression of ANKRD11 mRNA Arsenic Trioxide results in decreased expression of ANKRD11 mRNA
|
CTD |
PMID:20458559 PMID:22521957 |
|
NCBI chr19:67,848,836...68,007,491
Ensembl chr19:67,848,844...68,007,491
|
|
| G
|
Ankrd12
|
ankyrin repeat domain 12
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of ANKRD12 mRNA
|
CTD |
PMID:15761015 |
|
NCBI chr 9:113,030,127...113,134,816
Ensembl chr 9:113,030,919...113,134,762
|
|
| G
|
Ankrd2
|
ankyrin repeat domain 2
|
decreases response to substance
|
ISO
|
ANKRD2 protein results in decreased susceptibility to Arsenic Trioxide
|
CTD |
PMID:20707922 |
|
NCBI chr 1:250,796,419...250,805,867
Ensembl chr 1:250,796,409...250,805,870
|
|
| G
|
Ankrd23
|
ankyrin repeat domain 23
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of ANKRD23 mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr 9:46,269,107...46,274,578
Ensembl chr 9:46,269,107...46,274,510
|
|
| G
|
Ankrd28
|
ankyrin repeat domain 28
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of ANKRD28 mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr16:6,924,868...7,056,593
Ensembl chr16:6,924,882...7,056,593
|
|
| G
|
Ankrd29
|
ankyrin repeat domain 29
|
decreases expression increases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of ANKRD29 mRNA Arsenic Trioxide results in increased expression of ANKRD29 mRNA
|
CTD |
PMID:20458559 PMID:35676786 |
|
NCBI chr18:3,711,052...3,768,997
Ensembl chr18:3,711,059...3,769,098
|
|
| G
|
Ankrd39
|
ankyrin repeat domain 39
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to ANKRD39 protein]
|
CTD |
PMID:26598702 |
|
NCBI chr 9:46,277,659...46,286,050
Ensembl chr 9:46,279,952...46,286,043
|
|
| G
|
Ankrd40
|
ankyrin repeat domain 40
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to ANKRD40 protein]
|
CTD |
PMID:26598702 |
|
NCBI chr10:79,778,966...79,792,212
Ensembl chr10:56,415,260...56,416,345 Ensembl chr10:56,415,260...56,416,345
|
|
| G
|
Ankrd54
|
ankyrin repeat domain 54
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of ANKRD54 mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr 7:112,495,396...112,508,186
Ensembl chr 7:112,495,462...112,508,128
|
|
| G
|
Ankrd6
|
ankyrin repeat domain 6
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of ANKRD6 mRNA
|
CTD |
PMID:27829220 |
|
NCBI chr 5:51,999,225...52,139,623
Ensembl chr 5:51,999,221...52,139,594
|
|
| G
|
Anks1a
|
ankyrin repeat and sterile alpha motif domain containing 1A
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to ANKS1A protein]
|
CTD |
PMID:26598702 |
|
NCBI chr20:5,965,421...6,118,875
Ensembl chr20:5,965,028...6,118,875
|
|
| G
|
Anks1b
|
ankyrin repeat and sterile alpha motif domain containing 1B
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of ANKS1B mRNA
|
CTD |
PMID:24831965 |
|
NCBI chr 7:26,200,649...27,366,552
Ensembl chr 7:26,201,240...27,364,943
|
|
| G
|
Ano3
|
anoctamin 3
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of ANO3 mRNA
|
CTD |
PMID:26705709 PMID:39716349 |
|
NCBI chr 3:117,690,242...118,004,695
Ensembl chr 3:117,692,103...118,004,675
|
|
| G
|
Ano4
|
anoctamin 4
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of ANO4 mRNA
|
CTD |
PMID:35676786 |
|
NCBI chr 7:25,216,389...25,625,811
Ensembl chr 7:25,216,389...25,625,746
|
|
| G
|
Anp32b
|
acidic nuclear phosphoprotein 32 family member B
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of ANP32B mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 5:65,538,872...65,561,305
Ensembl chr 5:65,538,535...65,561,437
|
|
| G
|
Anpep
|
alanyl aminopeptidase, membrane
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of ANPEP mRNA
|
CTD |
PMID:15949261 |
|
NCBI chr 1:143,176,645...143,219,447
Ensembl chr 1:143,176,645...143,195,101
|
|
| G
|
Antxr1
|
ANTXR cell adhesion molecule 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of ANTXR1 mRNA
|
CTD |
PMID:22521957 |
|
NCBI chr 4:121,148,102...121,335,549
Ensembl chr 4:121,148,103...121,336,892
|
|
| G
|
Anxa1
|
annexin A1
|
decreases expression increases response to substance increases expression multiple interactions
|
ISO
|
Arsenic Trioxide results in decreased expression of ANXA1 protein ANXA1 mutant form results in increased susceptibility to Arsenic Trioxide Arsenic Trioxide results in increased expression of ANXA1 mRNA; Arsenic Trioxide results in increased expression of ANXA1 protein Arsenic Trioxide results in increased expression of and results in increased secretion of ANXA1 protein
|
CTD |
PMID:18081892 PMID:22521957 PMID:25258189 PMID:25983101 |
|
NCBI chr 1:227,287,713...227,306,739
Ensembl chr 1:227,287,717...227,306,831
|
|
| G
|
Anxa11
|
annexin A11
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to ANXA11 protein]
|
CTD |
PMID:26598702 |
|
NCBI chr16:1,419,627...1,464,590
Ensembl chr16:1,418,351...1,464,839
|
|
| G
|
Anxa2
|
annexin A2
|
multiple interactions increases expression decreases response to substance decreases expression
|
ISO
|
Arsenic Trioxide affects the localization of and results in decreased expression of ANXA2 protein; Arsenic Trioxide results in decreased expression of and results in increased degradation of ANXA2 mRNA Arsenic Trioxide results in increased expression of ANXA2 mRNA ANXA2 protein results in decreased susceptibility to Arsenic Trioxide Arsenic Trioxide results in decreased expression of ANXA2 mRNA; Arsenic Trioxide results in decreased expression of ANXA2 protein
|
CTD |
PMID:12165291 PMID:17547211 PMID:19642359 PMID:19781379 PMID:20707922 PMID:21223737 More...
|
|
NCBI chr 8:78,986,252...79,022,638
Ensembl chr 8:78,986,242...79,022,631
|
|
| G
|
Anxa3
|
annexin A3
|
decreases response to substance
|
ISO
|
ANXA3 protein results in decreased susceptibility to Arsenic Trioxide
|
CTD |
PMID:20707922 |
|
NCBI chr14:13,031,675...13,085,678
Ensembl chr14:13,023,762...13,085,849
|
|
| G
|
Anxa9
|
annexin A9
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to ANXA9 protein]
|
CTD |
PMID:26598702 |
|
NCBI chr 2:185,562,174...185,572,560
Ensembl chr 2:185,562,174...185,572,560
|
|
| G
|
Aoc3
|
amine oxidase, copper containing 3
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of AOC3 mRNA
|
CTD |
PMID:25258189 |
|
NCBI chr10:86,773,018...86,780,961
|
|
| G
|
Aopep
|
aminopeptidase O
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of AOPEP mRNA
|
CTD |
PMID:22521957 |
|
NCBI chr17:1,817,001...2,133,008
Ensembl chr17:1,817,001...2,133,104
|
|
| G
|
Ap1s1
|
adaptor related protein complex 1 subunit sigma 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of AP1S1 mRNA
|
CTD |
PMID:17258074 |
|
NCBI chr12:25,261,958...25,272,483
Ensembl chr12:25,262,036...25,272,483
|
|
| G
|
Ap2b1
|
adaptor related protein complex 2 subunit beta 1
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to AP2B1 protein]
|
CTD |
PMID:26598702 |
|
NCBI chr10:68,596,925...68,702,547
Ensembl chr10:68,597,093...68,702,539
|
|
| G
|
Ap2m1
|
adaptor related protein complex 2 subunit mu 1
|
multiple interactions
|
ISO
|
[Arsenic Trioxide co-treated with nilotinib] affects the expression of AP2M1 mRNA
|
CTD |
PMID:28786057 |
|
NCBI chr11:93,859,690...93,868,600
Ensembl chr11:93,859,690...93,868,480
|
|
| G
|
Ap3s1
|
adaptor related protein complex 3 subunit sigma 1
|
decreases expression increases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of AP3S1 mRNA Arsenic Trioxide results in increased expression of AP3S1 mRNA
|
CTD |
PMID:15761015 PMID:20458559 |
|
NCBI chr18:41,649,321...41,718,221
Ensembl chr18:41,648,796...41,767,641
|
|
| G
|
Apaf1
|
apoptotic peptidase activating factor 1
|
increases expression multiple interactions
|
ISO EXP
|
Arsenic Trioxide results in increased expression of APAF1 protein Arsenic Trioxide results in increased expression of APAF1 mRNA [Erlotinib Hydrochloride co-treated with Arsenic Trioxide] results in increased expression of APAF1 mRNA; [ruxolitinib co-treated with Arsenic Trioxide] results in increased expression of APAF1 mRNA
|
CTD |
PMID:19730151 PMID:25258189 PMID:29274334 PMID:30012499 |
|
NCBI chr 7:27,381,392...27,466,772
Ensembl chr 7:27,381,855...27,466,772
|
|
| G
|
Apbb1
|
amyloid beta precursor protein binding family B member 1
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of APBB1 mRNA
|
CTD |
PMID:19128835 PMID:22521957 |
|
NCBI chr 1:169,308,719...169,332,372
Ensembl chr 1:169,308,720...169,332,552
|
|
| G
|
Apbb1ip
|
amyloid beta precursor protein binding family B member 1 interacting protein
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of APBB1IP mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr17:89,849,474...89,941,099
Ensembl chr17:89,671,716...89,941,089
|
|
| G
|
Apbb2
|
amyloid beta precursor protein binding family B member 2
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of APBB2 mRNA
|
CTD |
PMID:26705709 PMID:35676786 |
|
NCBI chr14:41,849,638...42,232,930
Ensembl chr14:41,911,785...42,232,280
|
|
| G
|
Aplp1
|
amyloid beta precursor like protein 1
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of APLP1 mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr 1:94,824,330...94,834,705
Ensembl chr 1:94,824,072...94,834,610
|
|
| G
|
Aplp2
|
amyloid beta precursor like protein 2
|
multiple interactions increases expression
|
ISO
|
[Tretinoin co-treated with Arsenic Trioxide] results in increased expression of APLP2 mRNA Arsenic Trioxide results in increased expression of APLP2 mRNA
|
CTD |
PMID:15894607 PMID:27829220 |
|
NCBI chr 8:37,857,407...37,920,487
Ensembl chr 8:37,857,407...37,920,031
|
|
| G
|
Apoe
|
apolipoprotein E
|
multiple interactions decreases expression
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to APOE protein] Arsenic Trioxide results in decreased expression of APOE mRNA Arsenic Trioxide affects the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the cleavage of CASP3 protein]; Arsenic Trioxide affects the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the cleavage of IL1B protein]; Arsenic Trioxide affects the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of CD36 mRNA]; Arsenic Trioxide affects the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of CD36 protein]; Arsenic Trioxide affects the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of IL10 mRNA]; Arsenic Trioxide affects the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of IL10 protein]; Arsenic Trioxide affects the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of IL1B mRNA]; Arsenic Trioxide affects the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of IL6 mRNA]; Arsenic Trioxide affects the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of IL6 protein]; Arsenic Trioxide affects the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of NLRP3 mRNA]; Arsenic Trioxide affects the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of NLRP3 protein]; Arsenic Trioxide affects the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of TNF mRNA]
|
CTD |
PMID:22521957 PMID:26598702 PMID:38237221 |
|
NCBI chr 1:88,481,889...88,485,816
Ensembl chr 1:88,481,385...88,485,855
|
|
| G
|
App
|
amyloid beta precursor protein
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of APP mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr11:37,506,207...37,724,351
Ensembl chr11:37,506,408...37,722,971
|
|
| G
|
Aptx
|
aprataxin
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to APTX protein]
|
CTD |
PMID:26598702 |
|
NCBI chr 5:60,593,338...60,618,946
Ensembl chr 5:60,597,648...60,618,790
|
|
| G
|
Aqp1
|
aquaporin 1
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of AQP1 mRNA
|
CTD |
PMID:26705709 |
|
NCBI chr 4:85,812,784...85,824,964
Ensembl chr 4:85,812,784...85,830,504
|
|
| G
|
Aqp10
|
aquaporin 10
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of AQP10 mRNA
|
CTD |
PMID:22214486 |
|
NCBI chr 2:177,699,717...177,704,620
Ensembl chr 2:177,700,943...177,704,495
|
|
| G
|
Aqp3
|
aquaporin 3 (Gill blood group)
|
increases expression affects response to substance
|
ISO
|
Arsenic Trioxide results in increased expression of AQP3 mRNA AQP3 gene mutant form affects the susceptibility to Arsenic Trioxide
|
CTD |
PMID:22214486 PMID:30815697 PMID:38758479 |
|
NCBI chr 5:61,035,165...61,040,683
Ensembl chr 5:61,035,166...61,040,685
|
|
| G
|
Aqp4
|
aquaporin 4
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of AQP4 mRNA
|
CTD |
PMID:22214486 |
|
NCBI chr18:6,782,389...6,799,034
Ensembl chr18:6,782,389...6,799,098
|
|
| G
|
Aqp7
|
aquaporin 7
|
increases expression multiple interactions
|
ISO
|
Arsenic Trioxide results in increased expression of AQP7 mRNA [Arsenic Trioxide co-treated with Glucose] results in increased expression of AQP7 mRNA; [Arsenic Trioxide co-treated with Glucose] results in increased expression of AQP7 protein; INS protein inhibits the reaction [[Arsenic Trioxide co-treated with Glucose] results in increased expression of AQP7 mRNA]; INS protein inhibits the reaction [[Arsenic Trioxide co-treated with Glucose] results in increased expression of AQP7 protein]
|
CTD |
PMID:37146668 PMID:38758479 |
|
NCBI chr 5:60,968,495...60,982,618
Ensembl chr 5:60,967,558...60,982,618
|
|
| G
|
Aqp9
|
aquaporin 9
|
increases response to substance increases uptake affects expression increases expression increases import multiple interactions
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ISO
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AQP9 protein results in increased susceptibility to Arsenic Trioxide AQP9 protein results in increased uptake of Arsenic Trioxide Arsenic Trioxide affects the expression of AQP9 protein Arsenic Trioxide results in increased expression of AQP9 protein AQP9 protein results in increased import of Arsenic Trioxide [Azacitidine results in increased expression of AQP9 mRNA] which results in increased uptake of Arsenic Trioxide; [CSF3 protein results in increased expression of AQP9 mRNA] which results in increased uptake of Arsenic Trioxide; [CSF3 protein results in increased expression of AQP9 protein] which results in increased uptake of Arsenic Trioxide; [Tretinoin co-treated with Arsenic Trioxide] results in increased expression of AQP9 mRNA; [Tretinoin results in increased expression of AQP9 mRNA] which results in increased import of Arsenic Trioxide; [Tretinoin results in increased expression of AQP9 mRNA] which results in increased susceptibility to Arsenic Trioxide; AQP9 protein affects the reaction [Arsenic Trioxide promotes the reaction [Tretinoin results in decreased expression of and results in increased degradation of PIN1 protein]]; AQP9 protein affects the reaction [PIN1 protein affects the susceptibility to Arsenic Trioxide]; AQP9 protein affects the reaction [Tretinoin promotes the reaction [Arsenic Trioxide results in decreased expression of and results in increased degradation of PIN1 protein]]; AQP9 protein affects the uptake of and affects the susceptibility to Arsenic Trioxide; AQP9 protein promotes the reaction [CSF3 protein results in increased uptake of Arsenic Trioxide]; AQP9 protein results in increased uptake of and results in increased susceptibility to Arsenic Trioxide Arsenic Trioxide results in increased expression of AQP9 mRNA
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CTD |
PMID:15336539 PMID:16968895 PMID:19100828 PMID:19225113 PMID:21945491 PMID:23563754 PMID:25953102 PMID:30093655 PMID:35590355 PMID:38758479 More...
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NCBI chr 8:80,678,027...80,718,273
Ensembl chr 8:80,678,030...80,717,240
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| G
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Ar
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androgen receptor
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decreases expression multiple interactions decreases activity
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ISO
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Arsenic Trioxide results in decreased expression of AR mRNA Arsenic Trioxide results in decreased expression of AR protein Arsenic Trioxide inhibits the reaction [Metribolone promotes the reaction [AR protein binds to KLK3 promoter]] Arsenic Trioxide results in decreased activity of AR protein
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CTD |
PMID:19131511 PMID:19769630 PMID:28956719 |
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NCBI chr X:67,135,317...67,304,476
Ensembl chr X:67,135,317...67,304,467
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| G
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Arc
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activity-regulated cytoskeleton-associated protein
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decreases expression
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EXP
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Arsenic Trioxide results in decreased expression of ARC mRNA
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CTD |
PMID:29223816 |
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NCBI chr 7:108,444,959...108,448,413
Ensembl chr 7:108,444,692...108,451,220
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| G
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Arf1
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ARF GTPase 1
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increases expression
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ISO
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Arsenic Trioxide results in increased expression of ARF1 mRNA
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CTD |
PMID:20458559 PMID:39716349 |
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NCBI chr10:44,497,543...44,513,994
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| G
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Arfgap3
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ARF GTPase activating protein 3
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multiple interactions
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ISO
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Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to ARFGAP3 protein]
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CTD |
PMID:26598702 |
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NCBI chr 7:116,312,996...116,359,300
Ensembl chr 7:116,313,001...116,359,592
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| G
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Arfip1
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ARF interacting protein 1
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increases expression
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ISO
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Arsenic Trioxide results in increased expression of ARFIP1 mRNA
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CTD |
PMID:20458559 |
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NCBI chr 2:172,141,862...172,224,464
Ensembl chr 2:172,141,859...172,221,280
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| G
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Arfip2
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ARF interacting protein 2
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increases expression
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ISO
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Arsenic Trioxide results in increased expression of ARFIP2 mRNA
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CTD |
PMID:25258189 |
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NCBI chr 1:169,387,484...169,392,290
Ensembl chr 1:169,387,485...169,392,166
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| G
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Arg1
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arginase 1
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decreases expression
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ISO
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Arsenic Trioxide results in decreased expression of ARG1 mRNA
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CTD |
PMID:28454374 |
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NCBI chr 1:22,295,093...22,307,720
Ensembl chr 1:22,295,322...22,307,713
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| G
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Arhgap1
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Rho GTPase activating protein 1
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increases expression
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ISO
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Arsenic Trioxide results in increased expression of ARHGAP1 protein
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CTD |
PMID:25419056 |
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NCBI chr 3:98,077,064...98,099,163
Ensembl chr 3:98,077,150...98,099,154
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| G
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Arhgap18
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Rho GTPase activating protein 18
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decreases expression
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ISO
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Arsenic Trioxide results in decreased expression of ARHGAP18 mRNA
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CTD |
PMID:27829220 |
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NCBI chr 1:20,222,948...20,456,827
Ensembl chr 1:20,222,954...20,456,670
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| G
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Arhgap19
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Rho GTPase activating protein 19
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increases response to substance
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ISO
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ARHGAP19 protein results in increased susceptibility to Arsenic Trioxide
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CTD |
PMID:20707922 |
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NCBI chr 1:250,519,703...250,566,705
Ensembl chr 1:250,530,214...250,580,190
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| G
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Arhgap21
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Rho GTPase activating protein 21
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increases expression
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ISO
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Arsenic Trioxide results in increased expression of ARHGAP21 mRNA
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CTD |
PMID:20458559 |
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NCBI chr17:88,256,961...88,380,478
Ensembl chr17:88,256,961...88,380,797
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| G
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Arhgap26
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Rho GTPase activating protein 26
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multiple interactions
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ISO
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[Tretinoin co-treated with Arsenic Trioxide] results in decreased expression of ARHGAP26 mRNA
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CTD |
PMID:15894607 |
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NCBI chr18:30,702,602...31,489,047
Ensembl chr18:31,089,787...31,489,047
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| G
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Arhgap39
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Rho GTPase activating protein 39
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increases expression
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ISO
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Arsenic Trioxide results in increased expression of ARHGAP39 mRNA
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CTD |
PMID:39716349 |
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NCBI chr 7:110,326,918...110,419,500
Ensembl chr 7:110,326,918...110,419,460
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| G
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Arhgap5
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Rho GTPase activating protein 5
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increases expression
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ISO
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Arsenic Trioxide results in increased expression of ARHGAP5 mRNA
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CTD |
PMID:20458559 |
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NCBI chr 6:75,711,199...75,774,636
Ensembl chr 6:75,711,515...75,774,636
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| G
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Arhgap9
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Rho GTPase activating protein 9
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multiple interactions
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ISO
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[Tretinoin co-treated with Arsenic Trioxide] results in increased expression of ARHGAP9 mRNA
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CTD |
PMID:15894607 |
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NCBI chr 7:65,034,023...65,042,336
Ensembl chr 7:65,034,144...65,042,336
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| G
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Arhgdib
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Rho GDP dissociation inhibitor beta
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increases expression
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ISO
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Arsenic Trioxide results in increased expression of ARHGDIB mRNA
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CTD |
PMID:20458559 |
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NCBI chr 4:171,554,139...171,573,057
Ensembl chr 4:171,554,140...171,573,068
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| G
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Arhgef11
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Rho guanine nucleotide exchange factor 11
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increases expression
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ISO
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Arsenic Trioxide results in increased expression of ARHGEF11 mRNA
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CTD |
PMID:39716349 |
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NCBI chr 2:175,372,269...175,493,852
Ensembl chr 2:175,372,290...175,493,852
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| G
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Arid1a
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AT-rich interaction domain 1A
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increases sumoylation increases response to substance
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ISO
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Arsenic Trioxide results in increased sumoylation of ARID1A protein ARID1A protein results in increased susceptibility to Arsenic Trioxide
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CTD |
PMID:20707922 PMID:28318385 |
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NCBI chr 5:151,192,014...151,269,291
Ensembl chr 5:151,192,014...151,265,386
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| G
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Arid1b
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AT-rich interaction domain 1B
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decreases expression
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ISO
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Arsenic Trioxide results in decreased expression of ARID1B mRNA
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CTD |
PMID:20458559 |
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NCBI chr 1:47,973,199...48,328,793
Ensembl chr 1:47,973,997...48,328,793
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| G
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Arid2
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AT-rich interaction domain 2
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increases expression
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ISO
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Arsenic Trioxide results in increased expression of ARID2 mRNA
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CTD |
PMID:39716349 |
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NCBI chr 7:129,326,371...129,443,813
Ensembl chr 7:129,324,137...129,443,187
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| G
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Arid4a
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AT-rich interaction domain 4A
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increases expression
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ISO
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Arsenic Trioxide results in increased expression of ARID4A mRNA
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CTD |
PMID:35676786 |
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NCBI chr 6:95,258,429...95,335,987
Ensembl chr 6:95,258,429...95,329,840
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| G
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Arid4b
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AT-rich interaction domain 4B
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increases response to substance
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ISO
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ARID4B protein results in increased susceptibility to Arsenic Trioxide
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CTD |
PMID:20707922 |
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NCBI chr17:55,833,908...55,958,382
Ensembl chr17:55,833,908...55,958,382
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| G
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Arid5b
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AT-rich interaction domain 5B
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decreases expression
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ISO
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Arsenic Trioxide results in decreased expression of ARID5B mRNA
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CTD |
PMID:27829220 |
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NCBI chr20:20,305,693...20,489,689
Ensembl chr20:20,306,712...20,489,686
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| G
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Arl13b
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ARF like GTPase 13B
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decreases expression
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ISO
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Arsenic Trioxide results in decreased expression of ARL13B mRNA
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CTD |
PMID:39716349 |
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NCBI chr11:13,597,538...13,663,681
Ensembl chr11:13,597,538...13,663,546
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| G
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Arl3
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ARF like GTPase 3
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decreases expression
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ISO
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Arsenic Trioxide results in decreased expression of ARL3 mRNA
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CTD |
PMID:35676786 |
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NCBI chr 1:255,342,078...255,388,087
Ensembl chr 1:255,342,076...255,388,279
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| G
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Arl4c
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ARF like GTPase 4C
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decreases expression
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ISO
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Arsenic Trioxide results in decreased expression of ARL4C mRNA
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CTD |
PMID:15725085 |
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NCBI chr 9:96,748,075...96,751,510
Ensembl chr 9:96,745,069...96,752,772
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| G
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Arl5b
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ARF like GTPase 5B
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increases expression
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ISO
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Arsenic Trioxide results in increased expression of ARL5B mRNA
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CTD |
PMID:22521957 |
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NCBI chr17:82,864,315...82,888,458
Ensembl chr17:82,864,287...82,890,646
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| G
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Arl6ip1
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ARL6 interacting reticulophagy regulator 1
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increases expression
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ISO
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Arsenic Trioxide results in increased expression of ARL6IP1 mRNA
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CTD |
PMID:14703492 |
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NCBI chr 1:181,864,717...181,874,232
Ensembl chr 1:181,864,746...181,874,232
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| G
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Arl6ip5
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ARF like GTPase 6 interacting protein 5
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increases response to substance increases expression multiple interactions
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ISO
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ARL6IP5 protein results in increased susceptibility to Arsenic Trioxide Arsenic Trioxide results in increased expression of ARL6IP5 protein [Arsenic Trioxide results in increased abundance of Hydrogen Peroxide] which results in increased expression of ARL6IP5 protein; [Tretinoin co-treated with Arsenic Trioxide] results in increased expression of ARL6IP5 mRNA; ARL6IP5 protein promotes the reaction [Arsenic Trioxide results in increased cleavage of CASP9 protein]; ARL6IP5 protein promotes the reaction [Arsenic Trioxide results in increased phosphorylation of and results in increased activity of MAPK1 protein]; ARL6IP5 protein promotes the reaction [Arsenic Trioxide results in increased phosphorylation of and results in increased activity of MAPK3 protein]; CAT protein inhibits the reaction [[Arsenic Trioxide results in increased abundance of Hydrogen Peroxide] which results in increased expression of ARL6IP5 protein]
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CTD |
PMID:16430862 PMID:16468075 PMID:18387645 |
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NCBI chr 4:131,365,320...131,395,311
Ensembl chr 4:131,367,289...131,400,130
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| G
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Arl8b
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ARF like GTPase 8B
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multiple interactions
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ISO
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Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to ARL8B protein]
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CTD |
PMID:26598702 |
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NCBI chr 4:143,304,597...143,348,580
Ensembl chr 4:143,304,621...143,349,068
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| G
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Armc8
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armadillo repeat containing 8
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increases expression
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ISO
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Arsenic Trioxide results in increased expression of ARMC8 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 8:108,916,274...109,010,877
Ensembl chr 8:108,916,274...109,010,717
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| G
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Armc9
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armadillo repeat containing 9
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decreases expression
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ISO
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Arsenic Trioxide results in decreased expression of ARMC9 mRNA
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CTD |
PMID:15761015 |
|
NCBI chr 9:94,250,492...94,376,589
Ensembl chr 9:94,250,859...94,376,589
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| G
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Armcx3
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armadillo repeat containing, X-linked 3
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increases expression
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ISO
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Arsenic Trioxide results in increased expression of ARMCX3 protein
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CTD |
PMID:30093655 |
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NCBI chr X:102,230,464...102,234,017
Ensembl chr X:102,219,848...102,263,297
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| G
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Arnt2
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aryl hydrocarbon receptor nuclear translocator 2
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increases expression decreases expression
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ISO
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Arsenic Trioxide results in increased expression of ARNT2 mRNA Arsenic Trioxide results in decreased expression of ARNT2 mRNA
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CTD |
PMID:20458559 PMID:35676786 |
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NCBI chr 1:147,645,354...147,801,986
Ensembl chr 1:147,599,058...147,801,997
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| G
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Arpc1b
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actin related protein 2/3 complex, subunit 1B
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multiple interactions
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ISO
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[Tretinoin co-treated with Arsenic Trioxide] results in increased expression of ARPC1B mRNA
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CTD |
PMID:15894607 |
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NCBI chr12:14,595,939...14,609,501
Ensembl chr12:14,595,678...14,609,504
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| G
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Arpc3
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actin related protein 2/3 complex, subunit 3
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increases expression multiple interactions
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ISO
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Arsenic Trioxide results in increased expression of ARPC3 protein Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to ARPC3 protein]
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CTD |
PMID:25419056 PMID:26598702 |
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NCBI chr12:39,833,569...39,847,436
Ensembl chr12:39,833,569...39,847,436
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| G
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Arpc5l
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actin related protein 2/3 complex, subunit 5-like
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multiple interactions decreases expression
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ISO
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Metformin inhibits the reaction [Arsenic Trioxide results in decreased expression of ARPC5L mRNA]
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CTD |
PMID:29095437 |
|
NCBI chr 3:43,169,518...43,177,224
Ensembl chr 3:43,169,462...43,177,240 Ensembl chr 9:43,169,462...43,177,240
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| G
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Arpp19
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cAMP-regulated phosphoprotein 19
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multiple interactions increases expression
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ISO
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[Dasatinib co-treated with Arsenic Trioxide] results in decreased expression of ARPP19 mRNA; Arsenic Trioxide inhibits the reaction [Dasatinib results in increased expression of ARPP19 mRNA] Arsenic Trioxide results in increased expression of ARPP19 mRNA
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CTD |
PMID:29266867 |
|
NCBI chr 8:84,660,166...84,683,012
Ensembl chr 8:119,691,942...119,692,385 Ensembl chr 8:119,691,942...119,692,385
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| G
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Arrdc2
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arrestin domain containing 2
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increases expression
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ISO
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Arsenic Trioxide results in increased expression of ARRDC2 mRNA
|
CTD |
PMID:35676786 |
|
NCBI chr16:18,635,883...18,640,019
Ensembl chr16:18,635,883...18,640,158
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| G
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Arrdc3
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arrestin domain containing 3
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increases expression
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ISO
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Arsenic Trioxide results in increased expression of ARRDC3 mRNA
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CTD |
PMID:20458559 PMID:24356939 |
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NCBI chr 2:12,873,202...12,885,716
Ensembl chr 2:12,873,202...12,885,875
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| G
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Arxes1
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adipocyte-related X-chromosome expressed sequence 1
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decreases expression
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ISO
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Arsenic Trioxide results in decreased expression of ARXES1 mRNA
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CTD |
PMID:35676786 |
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NCBI chr X:103,742,157...103,743,676
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| G
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As3mt
|
arsenite methyltransferase
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multiple interactions affects metabolic processing affects response to substance increases expression
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EXP ISO
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Glutathione affects the reaction [AS3MT protein affects the metabolism of arsenous acid] AS3MT gene polymorphism affects the susceptibility to Arsenic Trioxide Arsenic Trioxide promotes the reaction [AS3MT protein binds to NLRP3 protein]; AS3MT mRNA promotes the reaction [Arsenic Trioxide inhibits the reaction [INS protein results in increased phosphorylation of GSK3B protein]]; AS3MT mRNA promotes the reaction [Arsenic Trioxide promotes the reaction [METTL14 protein binds to NLRP3 mRNA]]; AS3MT mRNA promotes the reaction [Arsenic Trioxide results in increased expression of CASP1 protein modified form]; AS3MT mRNA promotes the reaction [Arsenic Trioxide results in increased expression of IL1B protein]; AS3MT mRNA promotes the reaction [Arsenic Trioxide results in increased expression of NLRP3 protein]; AS3MT mRNA promotes the reaction [Arsenic Trioxide results in increased stability of NLRP3 mRNA]; Proanthocyanidins promotes the reaction [Arsenic Trioxide results in increased expression of AS3MT protein] Arsenic Trioxide results in increased expression of AS3MT mRNA; Arsenic Trioxide results in increased expression of AS3MT protein
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CTD |
PMID:15606138 PMID:30376134 PMID:31355259 PMID:35226250 PMID:36399430 |
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NCBI chr 1:255,536,879...255,569,245
Ensembl chr 1:255,537,109...255,569,249
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| G
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Asah1
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N-acylsphingosine amidohydrolase 1
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increases expression
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ISO
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Arsenic Trioxide results in increased expression of ASAH1 mRNA
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CTD |
PMID:20458559 PMID:27829220 |
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NCBI chr16:57,669,927...57,701,349
Ensembl chr16:57,669,750...57,718,305
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| G
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Asah2
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N-acylsphingosine amidohydrolase 2
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increases expression
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ISO
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Arsenic Trioxide results in increased expression of ASAH2 mRNA
|
CTD |
PMID:25258189 |
|
NCBI chr 1:239,278,994...239,386,598
Ensembl chr 1:239,278,994...239,382,024
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| G
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Asb11
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ankyrin repeat and SOCS box containing 11
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multiple interactions
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ISO
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Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to ASB11 protein]
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CTD |
PMID:26598702 |
|
NCBI chr X:33,646,389...33,669,790
Ensembl chr X:33,624,394...33,669,934
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| G
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Asb5
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ankyrin repeat and SOCS box-containing 5
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decreases expression
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ISO
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Arsenic Trioxide results in decreased expression of ASB5 mRNA
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CTD |
PMID:20458559 |
|
NCBI chr16:43,970,940...44,038,318
Ensembl chr16:43,970,940...44,010,437
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| G
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Asb8
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ankyrin repeat and SOCS box-containing 8
|
increases expression
|
ISO
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Arsenic Trioxide results in increased expression of ASB8 mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr 7:131,140,455...131,176,648
Ensembl chr 7:131,141,406...131,150,633
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| G
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Asb9
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ankyrin repeat and SOCS box-containing 9
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to ASB9 protein]
|
CTD |
PMID:26598702 |
|
NCBI chr X:33,588,484...33,633,285
Ensembl chr X:33,588,484...33,624,397
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| G
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Asic1
|
acid sensing ion channel subunit 1
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of ASIC1 mRNA
|
CTD |
PMID:26705709 |
|
NCBI chr 7:132,677,158...132,707,379
Ensembl chr 7:132,698,723...132,707,832
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| G
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Asl
|
argininosuccinate lyase
|
decreases response to substance increases expression
|
ISO
|
ASL protein results in decreased susceptibility to Arsenic Trioxide Arsenic Trioxide results in increased expression of ASL mRNA
|
CTD |
PMID:20458559 PMID:20707922 |
|
NCBI chr12:32,295,779...32,313,257
Ensembl chr12:32,295,633...32,317,261
|
|
| G
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Asns
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asparagine synthetase (glutamine-hydrolyzing)
|
decreases expression increases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of ASNS mRNA; Arsenic Trioxide results in decreased expression of ASNS protein Arsenic Trioxide results in increased expression of ASNS mRNA
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CTD |
PMID:17547211 PMID:24356939 PMID:25419056 |
|
NCBI chr 4:36,752,061...36,769,970
Ensembl chr 4:36,751,802...36,776,050
|
|
| G
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Asph
|
aspartate-beta-hydroxylase
|
decreases response to substance
|
ISO
|
ASPH protein results in decreased susceptibility to Arsenic Trioxide
|
CTD |
PMID:20707922 |
|
NCBI chr 5:27,398,933...27,611,519
Ensembl chr 5:27,398,949...27,611,215
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| G
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Aspm
|
assembly factor for spindle microtubules
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of ASPM mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr13:53,625,584...53,674,489
Ensembl chr13:53,625,584...53,674,489
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|
| G
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Asrgl1
|
asparaginase and isoaspartyl peptidase 1
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to ASRGL1 protein]
|
CTD |
PMID:26598702 |
|
NCBI chr 1:215,436,180...215,456,188
Ensembl chr 1:215,435,218...215,456,198
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|
| G
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Ass1
|
argininosuccinate synthase 1
|
multiple interactions decreases expression increases expression
|
ISO
|
[Tretinoin co-treated with Arsenic Trioxide] results in decreased expression of ASS1 mRNA Arsenic Trioxide results in decreased expression of ASS1 mRNA Arsenic Trioxide results in increased expression of ASS1 mRNA
|
CTD |
PMID:15070760 PMID:15761015 PMID:15894607 PMID:27829220 |
|
NCBI chr 3:35,144,765...35,194,632
Ensembl chr 3:35,144,999...35,194,627
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|
| G
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Asxl2
|
ASXL transcriptional regulator 2
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of ASXL2 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 6:32,090,497...32,234,487
Ensembl chr 6:32,145,607...32,227,851
|
|
| G
|
Atad2
|
ATPase family, AAA domain containing 2
|
increases expression multiple interactions
|
ISO
|
Arsenic Trioxide results in increased expression of ATAD2 mRNA [Dasatinib co-treated with Arsenic Trioxide] results in decreased expression of ATAD2 mRNA
|
CTD |
PMID:29266867 |
|
NCBI chr 7:91,523,626...91,566,238
Ensembl chr 7:91,523,626...91,566,238
|
|
| G
|
Atad3a
|
ATPase family, AAA domain containing 3A
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of ATAD3A protein
|
CTD |
PMID:25419056 |
|
NCBI chr 5:171,632,545...171,652,725
Ensembl chr 5:171,632,547...171,652,725
|
|
| G
|
Atat1
|
alpha tubulin acetyltransferase 1
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of ATAT1 mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr20:2,849,399...2,862,614
Ensembl chr20:2,849,421...2,862,389
|
|
| G
|
Atf2
|
activating transcription factor 2
|
increases phosphorylation multiple interactions
|
ISO
|
Arsenic Trioxide results in increased phosphorylation of ATF2 protein Arsenic Trioxide results in increased expression of and results in increased phosphorylation of ATF2 protein; Dasatinib promotes the reaction [Arsenic Trioxide results in increased phosphorylation of ATF2 protein]
|
CTD |
PMID:24934751 PMID:29266867 |
|
NCBI chr 3:79,125,814...79,202,896
Ensembl chr 3:79,126,705...79,202,745
|
|
| G
|
Atf3
|
activating transcription factor 3
|
decreases methylation decreases expression increases expression multiple interactions
|
ISO
|
Arsenic Trioxide results in decreased methylation of ATF3 promoter Arsenic Trioxide results in decreased expression of ATF3 mRNA Arsenic Trioxide results in increased expression of ATF3 mRNA ATF3 promotes the reaction [Arsenic Trioxide results in increased expression of MIR21 protein]
|
CTD |
PMID:20458559 PMID:26046465 PMID:36801614 PMID:38295932 |
|
NCBI chr13:105,274,103...105,331,653
Ensembl chr13:105,282,440...105,295,750
|
|
| G
|
Atf4
|
activating transcription factor 4
|
multiple interactions increases expression
|
ISO
|
Dasatinib inhibits the reaction [Arsenic Trioxide results in increased expression of ATF4 protein] 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt inhibits the reaction [Arsenic Trioxide results in increased expression of ATF4 protein]; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid inhibits the reaction [Arsenic Trioxide results in increased expression of ATF4 protein]; [Arsenic Trioxide results in increased abundance of Reactive Oxygen Species] which results in increased expression of ATF4 protein; Arsenic Trioxide results in increased expression of and affects the localization of ATF4 protein; ATF4 protein affects the reaction [Arsenic Trioxide results in decreased expression of IL1B mRNA]; ATF4 protein affects the reaction [Arsenic Trioxide results in decreased expression of ITGAM protein]; ATF4 protein affects the reaction [Arsenic Trioxide results in increased cleavage of CASP3 protein]; ATF4 protein affects the reaction [Arsenic Trioxide results in increased expression of IL10 mRNA]; ATF4 protein affects the reaction [Arsenic Trioxide results in increased expression of TGFB1 mRNA]; ATF4 protein affects the reaction [Arsenic Trioxide results in increased expression of TNF mRNA]; ATF4 protein promotes the reaction [Arsenic Trioxide affects the expression of DNM1L protein modified form]; ATF4 protein promotes the reaction [Arsenic Trioxide results in increased expression of and affects the localization of BAX protein]; ATF4 protein promotes the reaction [Arsenic Trioxide results in increased expression of and affects the localization of CYCS protein]; ATF4 protein promotes the reaction [Arsenic Trioxide results in increased expression of and affects the localization of RAC1 protein]; ATF4 protein promotes the reaction [Arsenic Trioxide results in increased expression of CAPN1 protein]; ATF4 protein promotes the reaction [Arsenic Trioxide results in increased expression of CASP12 protein modified form]; ATF4 protein promotes the reaction [Arsenic Trioxide results in increased expression of CASP3 protein modified form]; ATF4 protein promotes the reaction [Arsenic Trioxide results in increased expression of DDIT3 protein]; ATF4 protein promotes the reaction [Arsenic Trioxide results in increased expression of EIF2AK3 protein modified form]; ATF4 protein promotes the reaction [Arsenic Trioxide results in increased expression of HSP90B1 protein]; ATF4 protein promotes the reaction [Arsenic Trioxide results in increased expression of HSPA5 protein]; ATF4 protein promotes the reaction [Arsenic Trioxide results in increased expression of HSPA9 protein]; ATF4 protein promotes the reaction [Arsenic Trioxide results in increased expression of ITPR1 protein modified form]; ATF4 protein promotes the reaction [Arsenic Trioxide results in increased expression of NCF1 protein]; ATF4 protein promotes the reaction [Arsenic Trioxide results in increased expression of NCF2 protein]; ATF4 protein promotes the reaction [Arsenic Trioxide results in increased phosphorylation of TP53 protein]; Thioctic Acid inhibits the reaction [Arsenic Trioxide results in increased expression of ATF4 mRNA]; Thioctic Acid inhibits the reaction [Arsenic Trioxide results in increased expression of ATF4 protein] Arsenic Trioxide results in increased expression of ATF4 mRNA; Arsenic Trioxide results in increased expression of ATF4 protein
|
CTD |
PMID:23892647 PMID:27461142 PMID:27638049 PMID:29266867 |
|
NCBI chr 7:113,684,681...113,686,739
Ensembl chr 7:113,684,681...113,686,739
|
|
| G
|
Atf6
|
activating transcription factor 6
|
increases expression multiple interactions decreases expression increases phosphorylation
|
ISO
|
Arsenic Trioxide results in increased expression of ATF6 mRNA; Arsenic Trioxide results in increased expression of ATF6 protein 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt inhibits the reaction [Arsenic Trioxide results in increased expression of and results in increased cleavage of ATF6 protein]; [Arsenic Trioxide co-treated with antimony trichloride] results in increased expression of ATF6 mRNA; [Arsenic Trioxide results in increased abundance of Reactive Oxygen Species] which results in increased expression of and results in increased cleavage of ATF6 protein; Arsenic Trioxide results in increased expression of and results in increased cleavage of ATF6 protein; Thioctic Acid inhibits the reaction [Arsenic Trioxide results in increased expression of and results in increased cleavage of ATF6 protein]; Thioctic Acid inhibits the reaction [Arsenic Trioxide results in increased expression of ATF6 mRNA] Arsenic Trioxide results in decreased expression of ATF6 protein Arsenic Trioxide promotes the reaction [nilotinib results in decreased expression of ATF6 protein]; Resveratrol inhibits the reaction [Arsenic Trioxide results in increased expression of ATF6 protein] Arsenic Trioxide results in increased phosphorylation of ATF6 protein
|
CTD |
PMID:17963750 PMID:19176121 PMID:23883479 PMID:23892647 PMID:25107562 PMID:25258189 PMID:34091186 PMID:34560123 More...
|
|
NCBI chr13:85,460,312...85,639,959
Ensembl chr13:85,462,840...85,640,033
|
|
| G
|
Atf6b
|
activating transcription factor 6 beta
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of ATF6B protein
|
CTD |
PMID:25258189 |
|
NCBI chr20:4,095,534...4,103,534
Ensembl chr20:4,095,534...4,106,032
|
|
| G
|
Atg12
|
autophagy related 12
|
multiple interactions increases expression
|
ISO
|
Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased expression of ATG12 mRNA]; Arsenic Trioxide promotes the reaction [ATG5 protein binds to ATG12 protein]; TFEB protein affects the reaction [Arsenic Trioxide results in increased expression of ATG12 mRNA] Arsenic Trioxide results in increased expression of ATG12 mRNA; Arsenic Trioxide results in increased expression of ATG12 protein TFEB protein affects the reaction [Arsenic Trioxide results in increased expression of ATG12 protein]
|
CTD |
PMID:28978663 PMID:29307831 PMID:30032600 PMID:30225639 PMID:32112876 PMID:32781346 PMID:33462182 PMID:39716349 More...
|
|
NCBI chr18:41,638,841...41,649,311
Ensembl chr18:41,635,835...41,649,261
|
|
| G
|
Atg13
|
autophagy related 13
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of ATG13 mRNA
|
CTD |
PMID:32112876 |
|
NCBI chr 3:98,102,831...98,136,741
Ensembl chr 3:98,101,552...98,136,743
|
|
| G
|
Atg3
|
autophagy related 3
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of ATG3 mRNA
|
CTD |
PMID:31846860 PMID:32112876 PMID:32781346 |
|
NCBI chr11:69,130,948...69,159,280
Ensembl chr11:69,121,952...69,159,280
|
|
| G
|
Atg5
|
autophagy related 5
|
multiple interactions increases expression decreases expression
|
ISO EXP
|
Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased expression of ATG5 mRNA]; Arsenic Trioxide promotes the reaction [ATG5 protein binds to ATG12 protein]; ATG5 protein promotes the reaction [Arsenic Trioxide results in increased degradation of FLT3 protein mutant form]; Chloroquine promotes the reaction [Arsenic Trioxide results in increased expression of ATG5 protein]; TFEB protein affects the reaction [Arsenic Trioxide results in increased expression of ATG5 mRNA] Arsenic Trioxide results in increased expression of ATG5 mRNA; Arsenic Trioxide results in increased expression of ATG5 protein 3-methyladenine inhibits the reaction [Arsenic Trioxide results in increased expression of ATG5 mRNA]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased expression of ATG5 mRNA] Arsenic Trioxide results in decreased expression of ATG5 protein ferrostatin-1 inhibits the reaction [Arsenic Trioxide results in decreased expression of ATG5 protein]
|
CTD |
PMID:21594580 PMID:28978663 PMID:29307831 PMID:30032600 PMID:30225639 PMID:30338810 PMID:32112876 PMID:32284743 PMID:32781346 PMID:33462182 PMID:35195477 More...
|
|
NCBI chr20:49,380,835...49,471,826
Ensembl chr20:49,380,813...49,471,821
|
|
| G
|
Atg7
|
autophagy related 7
|
multiple interactions increases expression
|
ISO
|
Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased expression of ATG7 mRNA]; ATG7 protein promotes the reaction [Arsenic Trioxide results in increased degradation of BCR protein mutant form]; ATG7 protein promotes the reaction [Arsenic Trioxide results in increased degradation of FLT3 protein mutant form]; TFEB protein affects the reaction [Arsenic Trioxide results in increased expression of ATG7 mRNA] Arsenic Trioxide results in increased expression of ATG7 mRNA; Arsenic Trioxide results in increased expression of ATG7 protein 3-methyladenine inhibits the reaction [Arsenic Trioxide results in increased expression of ATG7 mRNA]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased expression of ATG7 mRNA]
|
CTD |
PMID:22898604 PMID:29307831 PMID:32284743 PMID:32781346 PMID:33462182 |
|
NCBI chr 4:149,390,000...149,597,534
Ensembl chr 4:149,391,390...149,598,319
|
|
| G
|
Atic
|
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of ATIC mRNA
|
CTD |
PMID:29633893 |
|
NCBI chr 9:80,614,311...80,634,360
Ensembl chr 9:80,614,283...80,635,756
|
|
| G
|
Atm
|
ATM serine/threonine kinase
|
decreases expression increases expression increases phosphorylation multiple interactions decreases phosphorylation
|
ISO EXP
|
Arsenic Trioxide results in decreased expression of ATM mRNA; Arsenic Trioxide results in decreased expression of ATM protein modified form Arsenic Trioxide results in increased expression of ATM mRNA Arsenic Trioxide results in increased phosphorylation of ATM protein [ruxolitinib co-treated with Arsenic Trioxide] results in increased phosphorylation of ATM protein; Erlotinib Hydrochloride promotes the reaction [Arsenic Trioxide results in increased expression of ATM mRNA] Arsenic Trioxide results in decreased phosphorylation of ATM protein
|
CTD |
PMID:19730151 PMID:19763917 PMID:20471514 PMID:23337567 PMID:28318385 PMID:29274334 PMID:30012499 PMID:31597699 More...
|
|
NCBI chr 8:62,724,939...62,829,040
Ensembl chr 8:62,727,291...62,828,629
|
|
| G
|
Atn1
|
atrophin 1
|
increases sumoylation
|
ISO
|
Arsenic Trioxide results in increased sumoylation of ATN1 protein
|
CTD |
PMID:28318385 |
|
NCBI chr 4:159,240,573...159,254,378
Ensembl chr 4:159,237,562...159,254,418
|
|
| G
|
Atoh1
|
atonal bHLH transcription factor 1
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of ATOH1 mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr 4:95,241,933...95,244,028
Ensembl chr 4:95,241,933...95,244,019
|
|
| G
|
Atp11c
|
ATPase phospholipid transporting 11C
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of ATP11C mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr X:143,600,763...143,788,407
Ensembl chr X:143,600,767...143,788,432
|
|
| G
|
Atp1b1
|
ATPase Na+/K+ transporting subunit beta 1
|
decreases response to substance decreases expression
|
ISO
|
ATP1B1 protein results in decreased susceptibility to Arsenic Trioxide Arsenic Trioxide results in decreased expression of ATP1B1 mRNA; Arsenic Trioxide results in decreased expression of ATP1B1 protein
|
CTD |
PMID:15761015 PMID:20707922 PMID:25419056 |
|
NCBI chr13:79,319,708...79,340,226
Ensembl chr13:79,319,706...79,340,549
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|
| G
|
Atp2a2
|
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2
|
decreases expression multiple interactions
|
ISO
|
Arsenic Trioxide results in decreased expression of ATP2A2 mRNA [Arsenic Trioxide co-treated with antimony trichloride] results in decreased expression of ATP2A2 mRNA; Arsenic Trioxide promotes the reaction [antimony trichloride results in decreased expression of ATP2A2 protein] Arsenic Trioxide results in decreased expression of ATP2A2 mRNA; Arsenic Trioxide results in decreased expression of ATP2A2 protein
|
CTD |
PMID:20458559 PMID:34091186 |
|
NCBI chr12:39,733,519...39,782,942
Ensembl chr12:39,733,458...39,782,934
|
|
| G
|
Atp2b1
|
ATPase plasma membrane Ca2+ transporting 1
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of ATP2B1 mRNA
|
CTD |
PMID:12852829 PMID:17547211 |
|
NCBI chr 7:35,622,267...35,731,904
Ensembl chr 7:35,622,461...35,731,904
|
|
| G
|
Atp5f1a
|
ATP synthase F1 subunit alpha
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of ATP5F1A mRNA
|
CTD |
PMID:15949261 PMID:19422848 |
|
NCBI chr18:73,567,537...73,575,473
Ensembl chr18:73,567,526...73,575,922
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|
| G
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Atp5f1c
|
ATP synthase F1 subunit gamma
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of ATP5F1C mRNA
|
CTD |
PMID:22521957 |
|
NCBI chr17:73,333,584...73,355,872
Ensembl chr17:73,333,588...73,383,073
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|
| G
|
Atp5if1
|
ATP synthase inhibitory factor subunit 1
|
increases expression decreases expression
|
ISO
|
Arsenic Trioxide results in increased expression of ATP5IF1 mRNA Arsenic Trioxide results in decreased expression of ATP5IF1 mRNA
|
CTD |
PMID:19422848 PMID:20458559 |
|
NCBI chr 5:150,022,960...150,026,677
Ensembl chr 5:150,022,960...150,026,677
|
|
| G
|
Atp5mc1
|
ATP synthase membrane subunit c locus 1
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of ATP5MC1 mRNA
|
CTD |
PMID:19422848 |
|
NCBI chr10:81,520,762...81,523,735
Ensembl chr10:81,520,765...81,523,363
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|
| G
|
Atp5mc2
|
ATP synthase membrane subunit c locus 2
|
multiple interactions decreases expression
|
ISO
|
Metformin inhibits the reaction [Arsenic Trioxide results in decreased expression of ATP5MC2 mRNA]
|
CTD |
PMID:29095437 |
|
NCBI chr 7:135,669,847...135,680,839
Ensembl chr 7:135,669,848...135,678,231
|
|
| G
|
Atp5me
|
ATP synthase membrane subunit e
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of ATP5ME mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr14:1,464,788...1,465,989
Ensembl chr14:1,464,800...1,465,988
|
|
| G
|
Atp6v0b
|
ATPase H+ transporting V0 subunit B
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of ATP6V0B mRNA
|
CTD |
PMID:29633893 |
|
NCBI chr 5:136,708,823...136,710,339
Ensembl chr 5:136,708,823...136,716,828
|
|
| G
|
Atp6v0d1
|
ATPase H+ transporting V0 subunit D1
|
increases expression multiple interactions
|
ISO
|
Arsenic Trioxide results in increased expression of ATP6V0D1 mRNA [Tretinoin co-treated with Arsenic Trioxide] results in increased expression of ATP6V0D1 mRNA; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased expression of ATP6V0D1 mRNA]; TFEB protein affects the reaction [Arsenic Trioxide results in increased expression of ATP6V0D1 mRNA]
|
CTD |
PMID:15894607 PMID:29307831 |
|
NCBI chr19:50,313,268...50,357,248
Ensembl chr19:50,313,273...50,357,395
|
|
| G
|
Atp6v1a
|
ATPase H+ transporting V1 subunit A
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of ATP6V1A mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr11:70,066,800...70,120,603
Ensembl chr11:70,035,134...70,120,603
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|
| G
|
Atp6v1e1
|
ATPase H+ transporting V1 subunit E1
|
multiple interactions increases expression
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to ATP6V1E1 protein] Arsenic Trioxide results in increased expression of ATP6V1E1 mRNA
|
CTD |
PMID:26598702 PMID:39716349 |
|
NCBI chr 4:155,694,534...155,716,660
Ensembl chr 4:155,694,534...155,716,678
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|
| G
|
Atp6v1g1
|
ATPase H+ transporting V1 subunit G1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of ATP6V1G1 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 5:81,976,959...81,983,139
Ensembl chr 5:81,977,015...81,985,930
|
|
| G
|
Atp6v1h
|
ATPase H+ transporting V1 subunit H
|
multiple interactions
|
ISO
|
[Arsenic Trioxide co-treated with apatinib] results in increased expression of ATP6V1H mRNA
|
CTD |
PMID:39223679 |
|
NCBI chr 5:19,176,849...19,282,516
Ensembl chr 5:19,176,849...19,282,516
|
|
| G
|
Atp7a
|
ATPase copper transporting alpha
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of ATP7A mRNA
|
CTD |
PMID:35676786 |
|
NCBI chr X:75,159,635...75,267,094
Ensembl chr X:75,159,782...75,267,093
|
|
| G
|
Atp8a1
|
ATPase phospholipid transporting 8A1
|
increases expression decreases expression
|
ISO
|
Arsenic Trioxide results in increased expression of ATP8A1 mRNA Arsenic Trioxide results in decreased expression of ATP8A1 mRNA
|
CTD |
PMID:15761015 PMID:35676786 |
|
NCBI chr14:40,668,932...40,911,465
Ensembl chr14:40,731,846...40,911,463
|
|
| G
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Atr
|
ATR serine/threonine kinase
|
increases expression increases activity multiple interactions
|
ISO
|
Arsenic Trioxide results in increased expression of ATR mRNA Arsenic Trioxide results in increased activity of ATR protein Erlotinib Hydrochloride promotes the reaction [Arsenic Trioxide results in increased expression of ATR mRNA]
|
CTD |
PMID:16891316 PMID:29274334 |
|
NCBI chr 8:105,306,299...105,403,742
Ensembl chr 8:105,306,305...105,403,718
|
|
| G
|
Atxn7
|
ataxin 7
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of ATXN7 mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr15:13,547,859...13,693,311
Ensembl chr15:13,547,862...13,693,526
|
|
| G
|
Aurka
|
aurora kinase A
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of AURKA protein
|
CTD |
PMID:16338065 |
|
NCBI chr 3:181,546,742...181,562,890
Ensembl chr 3:181,546,742...181,562,771
|
|
| G
|
Aurkc
|
aurora kinase C
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to AURKC protein]
|
CTD |
PMID:26598702 |
|
NCBI chr 1:75,876,773...75,882,893
Ensembl chr 1:75,876,773...75,897,426
|
|
| G
|
Auts2
|
activator of transcription and developmental regulator AUTS2
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of AUTS2 mRNA
|
CTD |
PMID:25555879 |
|
NCBI chr12:29,739,138...30,830,386
Ensembl chr12:29,740,523...30,830,386
|
|
| G
|
Avil
|
advillin
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of AVIL mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 7:64,711,294...64,729,436
Ensembl chr 7:64,711,403...64,729,436
|
|
| G
|
Axin2
|
axin 2
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of AXIN2 mRNA
|
CTD |
PMID:29633893 PMID:35676786 |
|
NCBI chr10:94,393,379...94,426,579
Ensembl chr10:94,395,909...94,426,575
|
|
| G
|
Azgp1
|
alpha-2-glycoprotein 1, zinc-binding
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of AZGP1 mRNA
|
CTD |
PMID:17547211 |
|
NCBI chr12:22,044,685...22,051,248
Ensembl chr12:22,044,751...22,053,020
|
|
| G
|
B3galt5
|
Beta-1,3-galactosyltransferase 5
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of B3GALT5 mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr11:49,053,959...49,100,398
Ensembl chr11:49,006,560...49,101,283
|
|
| G
|
B3gat3
|
beta-1,3-glucuronyltransferase 3
|
multiple interactions
|
ISO
|
[Tretinoin co-treated with Arsenic Trioxide] results in decreased expression of B3GAT3 mRNA
|
CTD |
PMID:15894607 |
|
NCBI chr 1:215,246,453...215,253,033
Ensembl chr 1:215,246,482...215,266,876
|
|
| G
|
B3gnt3
|
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
|
decreases response to substance
|
ISO
|
B3GNT3 protein results in decreased susceptibility to Arsenic Trioxide
|
CTD |
PMID:20707922 |
|
NCBI chr16:18,434,114...18,444,851
Ensembl chr16:18,435,378...18,444,738
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| G
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B3gnt6
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UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6
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decreases expression
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ISO
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Arsenic Trioxide results in decreased expression of B3GNT6 mRNA
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CTD |
PMID:20458559 |
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NCBI chr 1:161,897,504...161,915,046
Ensembl chr 1:161,898,323...161,903,354
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| G
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B3gntl1
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UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1
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increases expression
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ISO
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Arsenic Trioxide results in increased expression of B3GNTL1 mRNA
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CTD |
PMID:39716349 |
|
NCBI chr10:107,363,036...107,431,988
Ensembl chr10:107,371,442...107,431,908
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| G
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B4galnt1
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beta-1,4-N-acetyl-galactosaminyl transferase 1
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increases expression
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ISO
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Arsenic Trioxide results in increased expression of B4GALNT1 mRNA
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CTD |
PMID:22521957 |
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NCBI chr 7:64,873,909...64,881,512
Ensembl chr 7:64,874,022...64,881,516
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| G
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B4galt3
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beta-1,4-galactosyltransferase 3
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increases expression
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ISO
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Arsenic Trioxide results in increased expression of B4GALT3 mRNA
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CTD |
PMID:39716349 |
|
NCBI chr13:86,223,827...86,229,886
Ensembl chr13:86,223,899...86,229,888
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| G
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B4galt5
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beta-1,4-galactosyltransferase 5
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decreases expression decreases response to substance
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ISO
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Arsenic Trioxide results in decreased expression of B4GALT5 protein B4GALT5 protein results in decreased susceptibility to Arsenic Trioxide
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CTD |
PMID:18439752 |
|
NCBI chr 3:176,437,073...176,453,001
Ensembl chr 3:176,437,073...176,488,978
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| G
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Baalc
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BAALC binder of MAP3K1 and KLF4
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decreases expression
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ISO
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Arsenic Trioxide results in decreased expression of BAALC mRNA
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CTD |
PMID:19128835 PMID:26705709 |
|
NCBI chr 7:71,803,640...71,877,608
Ensembl chr 7:71,774,898...71,879,261
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| G
|
Babam1
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BRISC and BRCA1 A complex member 1
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multiple interactions
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ISO
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Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to BABAM1 protein]
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CTD |
PMID:26598702 |
|
NCBI chr16:18,102,885...18,108,916
Ensembl chr16:18,102,815...18,108,932
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| G
|
Bace1
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beta-secretase 1
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decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of BACE1 mRNA
|
CTD |
PMID:22521957 |
|
NCBI chr 8:55,038,842...55,061,138
Ensembl chr 8:55,038,823...55,064,918
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| G
|
Bach1
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BTB domain and CNC homolog 1
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affects localization multiple interactions increases expression
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ISO
|
Arsenic Trioxide affects the localization of BACH1 protein [Arsenic Trioxide results in increased abundance of Arsenic] which results in increased expression of and affects the localization of BACH1 protein; [Arsenic Trioxide results in increased abundance of Arsenic] which results in increased expression of BACH1 mRNA; Acetylcysteine inhibits the reaction [Arsenic Trioxide affects the localization of BACH1 protein]; MIR155 mRNA inhibits the reaction [Arsenic Trioxide results in increased expression of BACH1 protein]
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CTD |
PMID:19350554 PMID:29260515 PMID:33434570 |
|
NCBI chr11:40,425,721...40,461,118
Ensembl chr11:40,425,664...40,461,277
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| G
|
Bach2
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BTB domain and CNC homolog 2
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of BACH2 mRNA
|
CTD |
PMID:15725085 |
|
NCBI chr 5:51,428,802...51,779,030
Ensembl chr 5:51,434,870...51,774,234
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| G
|
Bad
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BCL2-associated agonist of cell death
|
multiple interactions decreases phosphorylation decreases expression increases expression affects expression
|
EXP ISO
|
salvianolic acid A inhibits the reaction [Arsenic Trioxide results in increased expression of BAD protein] Arsenic Trioxide results in decreased phosphorylation of BAD protein Arsenic Trioxide results in decreased expression of BAD protein Arsenic Trioxide results in decreased expression of BAD mRNA Arsenic Trioxide results in increased expression of BAD mRNA; Arsenic Trioxide results in increased expression of BAD protein Arsenic Trioxide affects the expression of BAD protein [Arsenic Trioxide co-treated with Curcumin] results in increased expression of BAD protein; [Arsenic Trioxide co-treated with NVP-BKM120] results in increased expression of BAD mRNA; Arsenic Trioxide promotes the reaction [Aprepitant results in increased expression of BAD mRNA]; Arsenic Trioxide results in increased phosphorylation of and results in increased activity of BAD protein; Erlotinib Hydrochloride promotes the reaction [Arsenic Trioxide results in increased expression of BAD mRNA]; NVP-BKM120 promotes the reaction [Arsenic Trioxide results in increased expression of BAD mRNA]; salvin promotes the reaction [Arsenic Trioxide results in decreased phosphorylation of BAD protein]
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CTD |
PMID:15073043 PMID:17530438 PMID:18349030 PMID:18387645 PMID:18618274 PMID:19364129 PMID:19730151 PMID:23239002 PMID:27430728 PMID:28391263 PMID:29274334 PMID:30145367 PMID:30316766 PMID:31539632 PMID:34413873 More...
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|
NCBI chr 1:213,562,719...213,572,034
Ensembl chr 1:213,562,187...213,572,034
|
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| G
|
Bag1
|
BAG cochaperone 1
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of BAG1 mRNA
|
CTD |
PMID:17530438 |
|
NCBI chr 5:60,864,476...60,877,059
Ensembl chr 5:60,864,476...60,878,161
|
|
| G
|
Bag3
|
BAG cochaperone 3
|
affects expression
|
ISO
|
Arsenic Trioxide affects the expression of BAG3 mRNA
|
CTD |
PMID:17530438 |
|
NCBI chr 1:192,533,460...192,557,281
Ensembl chr 1:192,475,828...192,557,280
|
|
| G
|
Baiap2l1
|
BAR/IMD domain containing adaptor protein 2 like 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of BAIAP2L1 mRNA
|
CTD |
PMID:26705709 |
|
NCBI chr12:15,364,090...15,453,602
Ensembl chr12:15,364,109...15,453,605
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|
| G
|
Bak1
|
BCL2-antagonist/killer 1
|
increases expression decreases expression multiple interactions affects response to substance
|
ISO EXP
|
Arsenic Trioxide results in increased expression of BAK1 protein Arsenic Trioxide results in decreased expression of BAK1 mRNA [Arsenic Trioxide co-treated with apatinib] results in increased expression of BAK1 protein; [Arsenic Trioxide co-treated with Ascorbic Acid co-treated with Disulfiram] results in decreased expression of BAK1 protein BAK1 protein affects the susceptibility to Arsenic Trioxide Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased expression of BAK1 mRNA]; Arsenic Trioxide promotes the reaction [Drugs, Chinese Herbal results in increased expression of BAK1 protein]
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CTD |
PMID:11940349 PMID:15979664 PMID:17530438 PMID:19695276 PMID:19730151 PMID:21533816 PMID:24126434 PMID:25174355 PMID:25335113 PMID:28587418 PMID:39223679 More...
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|
NCBI chr20:5,102,334...5,111,615
Ensembl chr20:5,102,335...5,110,974
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|
| G
|
Bambi
|
BMP and activin membrane-bound inhibitor
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of BAMBI mRNA
|
CTD |
PMID:15725085 |
|
NCBI chr17:58,816,438...58,821,003
Ensembl chr17:58,816,442...58,821,247
|
|
| G
|
Banf1
|
barrier to autointegration nuclear assembly factor 1
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of BANF1 protein
|
CTD |
PMID:25419056 |
|
NCBI chr 1:212,101,523...212,103,568
Ensembl chr 1:212,101,523...212,103,552
|
|
| G
|
Bap1
|
BRCA1 associated deubiquitinase 1
|
affects expression
|
ISO
|
Arsenic Trioxide affects the expression of BAP1 mRNA
|
CTD |
PMID:17530438 |
|
NCBI chr16:6,453,126...6,461,952
Ensembl chr16:6,452,974...6,461,952
|
|
| G
|
Basp1
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brain abundant, membrane attached signal protein 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of BASP1 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 2:77,546,628...77,594,297
Ensembl chr 2:77,546,092...77,597,178
|
|
| G
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Bax
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BCL2 associated X, apoptosis regulator
|
increases activity affects localization increases expression increases response to substance multiple interactions affects expression decreases expression affects response to substance increases cleavage
|
ISO EXP
|
Arsenic Trioxide results in increased activity of BAX protein Arsenic Trioxide affects the localization of BAX protein Arsenic Trioxide results in increased expression of BAX mRNA; Arsenic Trioxide results in increased expression of BAX protein BAX results in increased susceptibility to Arsenic Trioxide 18alpha,20beta-hydroxy-11-oxo-norolean-12-en-3beta-yl-2-O-beta-D-glucopyranurosyl-alpha-D-glucopyranosiduronate magnesium tetrahydrate inhibits the reaction [Arsenic Trioxide results in increased expression of BAX protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased expression of BAX mRNA]; Arsenic Trioxide results in increased expression of and affects the localization of BAX protein; ATF4 protein promotes the reaction [Arsenic Trioxide results in increased expression of and affects the localization of BAX protein]; baicalin inhibits the reaction [Arsenic Trioxide results in increased expression of BAX mRNA]; baicalin inhibits the reaction [Arsenic Trioxide results in increased expression of BAX protein]; MIR34A affects the reaction [Arsenic Trioxide results in increased expression of BAX protein]; Propranolol inhibits the reaction [Arsenic Trioxide results in increased expression of BAX protein]; Thioctic Acid inhibits the reaction [Arsenic Trioxide results in increased expression of BAX mRNA] Arsenic Trioxide affects the expression of BAX; Arsenic Trioxide affects the expression of BAX protein Arsenic Trioxide results in decreased expression of BAX protein Arsenic Trioxide results in decreased expression of BAX mRNA; Arsenic Trioxide results in decreased expression of BAX protein BAX protein affects the susceptibility to Arsenic Trioxide Arsenic Trioxide results in increased expression of BAX; Arsenic Trioxide results in increased expression of BAX mRNA; Arsenic Trioxide results in increased expression of BAX protein 2-(4-nitrophenyl)-4-(4-fluorophenyl)-5-(4-pyridinyl)-1H-imidazole inhibits the reaction [Arsenic Trioxide affects the localization of BAX protein]; 3,4-dihydro-5-(4-(1-piperidinyl)butoxy)-1(2H)-isoquinolinone inhibits the reaction [[Arsenic Trioxide co-treated with phytosphingosine] results in increased localization of BAX protein]; [Arsenic Trioxide co-treated with 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one] results in increased activity of BAX protein; [Arsenic Trioxide co-treated with Ascorbic Acid co-treated with Disulfiram] results in increased expression of BAX protein; [Arsenic Trioxide co-treated with Calcitriol] results in increased expression of BAX mRNA; [Arsenic Trioxide co-treated with Calcitriol] results in increased expression of BAX protein; [Arsenic Trioxide co-treated with Curcumin] results in increased expression of BAX protein; [Arsenic Trioxide co-treated with Doxorubicin co-treated with Magnetite Nanoparticles analog] affects the expression of BAX mRNA; [Arsenic Trioxide co-treated with Doxorubicin co-treated with Magnetite Nanoparticles analog] affects the expression of BAX protein; [Arsenic Trioxide co-treated with NVP-BKM120] results in increased expression of BAX mRNA; [Arsenic Trioxide co-treated with phytosphingosine] results in increased localization of BAX protein; [Arsenic Trioxide results in increased phosphorylation of BCL2 protein] inhibits the reaction [BCL2 protein binds to BAX protein]; [Arsenic Trioxide results in increased susceptibility to Ascorbic Acid] which results in increased expression of BAX protein; [Bortezomib co-treated with Arsenic Trioxide] affects the expression of BAX protein; [CpG ODN 2216 co-treated with Arsenic Trioxide] results in increased expression of BAX protein; [Curcumin co-treated with Arsenic Trioxide] results in increased expression of BAX protein; [Docosahexaenoic Acids co-treated with Arsenic Trioxide] results in increased expression of BAX protein; [MARVELD1 protein results in decreased susceptibility to Arsenic Trioxide] which results in decreased expression of BAX protein; [NVP-BKM120 co-treated with Arsenic Trioxide] results in increased expression of BAX mRNA; [ruxolitinib co-treated with Arsenic Trioxide] results in increased expression of BAX mRNA; [tetraarsenic tetrasulfide co-treated with Arsenic Trioxide] results in increased expression of BAX mRNA; [tetraarsenic tetrasulfide co-treated with Arsenic Trioxide] results in increased expression of BAX protein; [Valproic Acid co-treated with Arsenic Trioxide] results in increased expression of BAX mRNA; [Valproic Acid co-treated with Arsenic Trioxide] results in increased expression of BAX protein; Acetylcysteine inhibits the reaction [[Arsenic Trioxide co-treated with phytosphingosine] results in increased localization of BAX protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide affects the localization of BAX protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased expression of BAX protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased localization of BAX protein]; Acetylcysteine inhibits the reaction [Resveratrol promotes the reaction [Arsenic Trioxide results in increased expression of BAX protein]]; allicin inhibits the reaction [Arsenic Trioxide results in increased expression of BAX protein]; Arsenic Trioxide inhibits the reaction [BCL2 protein binds to BAX protein binds to VDAC1 protein]; Arsenic Trioxide inhibits the reaction [BCL2 protein binds to BAX protein]; Arsenic Trioxide promotes the reaction [Aprepitant results in increased expression of BAX mRNA]; Arsenic Trioxide promotes the reaction [BAX protein binds to BAX protein]; Arsenic Trioxide promotes the reaction [Curcumin affects the localization of BAX protein]; Arsenic Trioxide promotes the reaction [Genistein results in increased expression of BAX protein]; Arsenic Trioxide promotes the reaction [Quercetin results in increased activity of BAX protein]; Arsenic Trioxide results in increased activity of and affects the localization of BAX protein; Arsenic Trioxide results in increased cleavage of and results in increased expression of BAX protein; Arsenic Trioxide results in increased localization of and results in increased activity of BAX protein; BAX mutant form inhibits the reaction [Arsenic Trioxide affects the localization of AIFM1 protein]; BCL2 protein inhibits the reaction [Arsenic Trioxide inhibits the reaction [BCL2 protein binds to BAX protein]]; BCL2 protein inhibits the reaction [Arsenic Trioxide results in increased activity of BAX protein]; benzyloxycarbonyl-valyl-alanyl-aspartic acid analog inhibits the reaction [Arsenic Trioxide results in increased cleavage of BAX protein]; calpeptin inhibits the reaction [Arsenic Trioxide results in increased cleavage of BAX protein]; Curcumin promotes the reaction [Arsenic Trioxide affects the localization of BAX protein]; Deoxyglucose promotes the reaction [Arsenic Trioxide results in increased localization of and results in increased activity of BAX protein]; Erlotinib Hydrochloride promotes the reaction [Arsenic Trioxide results in increased expression of BAX mRNA]; Gemcitabine promotes the reaction [Arsenic Trioxide results in increased expression of BAX protein]; Genistein promotes the reaction [Arsenic Trioxide results in increased expression of BAX protein]; GH1 protein promotes the reaction [Arsenic Trioxide results in increased expression of BAX mRNA]; GRB10 protein promotes the reaction [[Arsenic Trioxide co-treated with apatinib] results in increased expression of BAX protein]; Hydrogen Peroxide inhibits the reaction [Arsenic Trioxide results in increased expression of BAX protein]; ID1 protein inhibits the reaction [Arsenic Trioxide results in increased expression of BAX protein]; MAPK14 mutant form inhibits the reaction [Arsenic Trioxide affects the localization of BAX protein]; MARVELD1 protein inhibits the reaction [Arsenic Trioxide results in increased expression of BAX protein]; MMP9 protein inhibits the reaction [Arsenic Trioxide results in increased expression of BAX protein]; MT2A protein inhibits the reaction [Arsenic Trioxide results in increased expression of BAX protein]; pyrazolanthrone promotes the reaction [Arsenic Trioxide results in increased activity of and results in increased localization of BAX protein]; Quercetin promotes the reaction [Arsenic Trioxide results in increased activity of BAX protein]; Resveratrol promotes the reaction [Arsenic Trioxide results in increased expression of BAX protein]; SB 203580 inhibits the reaction [[Arsenic Trioxide co-treated with phytosphingosine] results in increased localization of BAX protein]; Thioctic Acid inhibits the reaction [Arsenic Trioxide results in increased localization of BAX protein]; TNF protein promotes the reaction [Arsenic Trioxide affects the localization of BAX protein]; U 0126 promotes the reaction [Arsenic Trioxide results in increased activity of and results in increased localization of BAX protein]; Wortmannin inhibits the reaction [Hydrogen Peroxide inhibits the reaction [Arsenic Trioxide results in increased expression of BAX protein]] 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [salvianolic acid B inhibits the reaction [Arsenic Trioxide results in increased expression of BAX protein]]; [Arsenic Trioxide results in increased abundance of Arsenic] which results in increased expression of BAX protein; Apigenin inhibits the reaction [[Arsenic Trioxide results in increased abundance of Arsenic] which results in increased expression of BAX protein]; crocin inhibits the reaction [Arsenic Trioxide results in increased expression of BAX mRNA]; crocin inhibits the reaction [Arsenic Trioxide results in increased expression of BAX protein]; ferrostatin-1 inhibits the reaction [Arsenic Trioxide results in increased expression of BAX protein]; HTS 466284 inhibits the reaction [Arsenic Trioxide results in increased expression of BAX protein]; Phloretin inhibits the reaction [Arsenic Trioxide results in increased expression of BAX mRNA]; salvianolic acid A inhibits the reaction [Arsenic Trioxide results in increased expression of BAX protein]; salvianolic acid B inhibits the reaction [Arsenic Trioxide results in increased expression of BAX protein]; trans-sodium crocetinate inhibits the reaction [Arsenic Trioxide results in increased expression of BAX protein]
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CTD |
PMID:10712780 PMID:11135700 PMID:11775218 PMID:11940349 PMID:12429934 PMID:12609832 PMID:12725324 PMID:12883267 PMID:15131059 PMID:15142122 PMID:15665116 PMID:15735709 PMID:15979664 PMID:16010437 PMID:16020671 PMID:16867262 PMID:16882451 PMID:16972261 PMID:17203211 PMID:17237268 PMID:17258074 PMID:17374990 PMID:17673311 PMID:18349030 PMID:18359480 PMID:18412143 PMID:18718063 PMID:19208092 PMID:19260322 PMID:19364129 PMID:19489279 PMID:19695276 PMID:19769630 PMID:20164150 PMID:20200477 PMID:20219070 PMID:20403207 PMID:20408844 PMID:20458559 PMID:20605902 PMID:21061466 PMID:21418039 PMID:21533816 PMID:21565247 PMID:21594580 PMID:21889928 PMID:23041229 PMID:23201927 PMID:23337567 PMID:23382965 PMID:23542815 PMID:23664956 PMID:23851143 PMID:23892647 PMID:24126434 PMID:24157283 PMID:24466103 PMID:24738333 PMID:24944602 PMID:24956101 PMID:24993472 PMID:25174355 PMID:25416439 PMID:25787108 PMID:25815518 PMID:25972196 PMID:26110921 PMID:26772155 PMID:27039805 PMID:27430728 PMID:27461142 PMID:27561292 PMID:27638049 PMID:28391263 PMID:28454374 PMID:29274334 PMID:29610575 PMID:30012499 PMID:30091188 PMID:30145367 PMID:30316766 PMID:30333888 PMID:30472098 PMID:30551535 PMID:31079498 PMID:31205918 PMID:31258454 PMID:31539632 PMID:32096187 PMID:32642412 PMID:32919218 PMID:32920515 PMID:33173984 PMID:33603344 PMID:33846815 PMID:34025784 PMID:34037972 PMID:34333357 PMID:34413873 PMID:35088608 PMID:35195477 PMID:35317438 PMID:35676786 PMID:36352148 PMID:36400307 PMID:36707890 PMID:37730986 PMID:38130211 PMID:38160894 PMID:39223679 More...
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NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429
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| G
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Bbc3
|
Bcl-2 binding component 3
|
multiple interactions increases expression decreases expression
|
ISO
|
[Arsenic Trioxide co-treated with VS-5584] results in increased expression of BBC3 mRNA; [Erlotinib Hydrochloride co-treated with Arsenic Trioxide] results in increased expression of BBC3 mRNA; [ruxolitinib co-treated with Arsenic Trioxide] results in increased expression of BBC3 mRNA; [sanguinarine co-treated with Arsenic Trioxide] results in increased expression of BBC3 mRNA; Dasatinib promotes the reaction [Arsenic Trioxide results in increased expression of BBC3 protein]; pyrazolanthrone inhibits the reaction [Arsenic Trioxide results in increased expression of BBC3 protein] 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt inhibits the reaction [Arsenic Trioxide results in increased expression of BBC3 mRNA]; Thioctic Acid inhibits the reaction [Arsenic Trioxide results in increased expression of BBC3 mRNA] Arsenic Trioxide results in increased expression of BBC3 mRNA; Arsenic Trioxide results in increased expression of BBC3 protein Arsenic Trioxide results in decreased expression of BBC3 protein
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CTD |
PMID:17374990 PMID:20723298 PMID:21454520 PMID:23892647 PMID:24345465 PMID:29266867 PMID:29274334 PMID:29574283 PMID:30012499 PMID:30472098 More...
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NCBI chr 1:86,141,450...86,150,666
Ensembl chr 1:86,141,603...86,150,666
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|
| G
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Bbs4
|
Bardet-Biedl syndrome 4
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of BBS4 mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr 8:68,627,739...68,661,232
Ensembl chr 8:68,627,656...68,661,358
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| G
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Bbs9
|
Bardet-Biedl syndrome 9
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of BBS9 mRNA
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CTD |
PMID:20458559 |
|
NCBI chr 8:29,288,846...29,713,889
Ensembl chr 8:29,289,997...29,713,880
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|
| G
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Bcar1
|
BCAR1 scaffold protein, Cas family member
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to BCAR1 protein]
|
CTD |
PMID:26598702 |
|
NCBI chr19:56,588,500...56,623,190
Ensembl chr19:56,588,500...56,623,190
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| G
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Bcat2
|
branched chain amino acid transaminase 2
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of BCAT2 mRNA
|
CTD |
PMID:25258189 |
|
NCBI chr 1:105,175,157...105,196,474
Ensembl chr 1:105,176,977...105,196,463
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|
| G
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Bccip
|
BRCA2 and CDKN1A interacting protein
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to BCCIP protein]
|
CTD |
PMID:26598702 |
|
NCBI chr 1:197,942,535...197,954,948
Ensembl chr 1:197,942,190...197,956,378
|
|
| G
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Bche
|
butyrylcholinesterase
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of BCHE mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 2:160,607,289...160,699,760
Ensembl chr 2:160,606,288...160,699,760
|
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| G
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Bcl10
|
BCL10, immune signaling adaptor
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of BCL10 mRNA
|
CTD |
PMID:17530438 |
|
NCBI chr 2:237,501,181...237,510,821
Ensembl chr 2:237,501,134...237,511,829
|
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| G
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Bcl2
|
BCL2, apoptosis regulator
|
increases cleavage multiple interactions decreases expression affects response to substance affects folding affects expression decreases response to substance increases expression increases phosphorylation increases degradation increases response to substance
|
ISO EXP
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Arsenic Trioxide results in increased cleavage of BCL2 protein 2-(4-nitrophenyl)-4-(4-fluorophenyl)-5-(4-pyridinyl)-1H-imidazole inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of BCL2 protein]; 3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [Arsenic Trioxide affects the localization of BCL2 protein]; 3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [Arsenic Trioxide results in increased expression of BCL2 mRNA]; 3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [Arsenic Trioxide results in increased expression of BCL2 protein]; 3-methyladenine inhibits the reaction [Arsenic Trioxide results in decreased expression of BCL2]; 4-amino-1,8-naphthalimide inhibits the reaction [Arsenic Trioxide results in increased expression of BCL2 protein]; [Arsenic Trioxide co-treated with apatinib] results in decreased expression of BCL2 protein; [Arsenic Trioxide co-treated with Aprepitant] results in decreased expression of BCL2 mRNA; [Arsenic Trioxide co-treated with Ascorbic Acid co-treated with Disulfiram] results in decreased expression of BCL2 protein; [Arsenic Trioxide co-treated with BCL2 mutant form] results in increased expression of BCL2 protein; [Arsenic Trioxide co-treated with Bortezomib] results in decreased expression of BCL2 mRNA; [Arsenic Trioxide co-treated with Calcitriol] results in decreased expression of BCL2 mRNA; [Arsenic Trioxide co-treated with Calcitriol] results in decreased expression of BCL2 protein; [Arsenic Trioxide co-treated with Curcumin] affects the expression of BCL2 protein; [Arsenic Trioxide co-treated with Doxorubicin co-treated with Magnetite Nanoparticles analog] affects the expression of BCL2 mRNA; [Arsenic Trioxide co-treated with Doxorubicin co-treated with Magnetite Nanoparticles analog] affects the expression of BCL2 protein; [Arsenic Trioxide co-treated with epigallocatechin gallate] results in decreased expression of BCL2 protein; [Arsenic Trioxide co-treated with NVP-BKM120] results in decreased expression of BCL2 mRNA; [Arsenic Trioxide co-treated with PML protein] results in decreased expression of BCL2; [Arsenic Trioxide results in increased phosphorylation of BCL2 protein] inhibits the reaction [BCL2 protein binds to BAX protein]; [BIBR 1532 co-treated with Arsenic Trioxide] affects the expression of BCL2 mRNA; [Bortezomib co-treated with Arsenic Trioxide] affects the expression of BCL2 protein; [Bortezomib co-treated with Arsenic Trioxide] results in decreased expression of BCL2 protein; [Curcumin co-treated with Arsenic Trioxide] results in decreased expression of BCL2 protein; [Erlotinib Hydrochloride co-treated with Arsenic Trioxide] results in decreased expression of BCL2 mRNA; [Genistein co-treated with Arsenic Trioxide] results in decreased expression of BCL2 protein; [Hydrogen Peroxide co-treated with Arsenic Trioxide] results in decreased expression of BCL2 protein; [MARVELD1 protein results in decreased susceptibility to Arsenic Trioxide] which results in increased expression of BCL2 protein; [paricalcitol co-treated with Arsenic Trioxide] results in decreased expression of BCL2; [pifithrin co-treated with Arsenic Trioxide] results in decreased expression of BCL2 protein; [ruxolitinib co-treated with Arsenic Trioxide] results in decreased expression of BCL2 mRNA; [Silybin co-treated with Arsenic Trioxide] results in decreased expression of BCL2 mRNA; [tetraarsenic tetrasulfide co-treated with Arsenic Trioxide] results in decreased expression of BCL2 mRNA; [tetraarsenic tetrasulfide co-treated with Arsenic Trioxide] results in decreased expression of BCL2 protein; [Tretinoin co-treated with Arsenic Trioxide] results in decreased expression of BCL2 mRNA; [Valproic Acid co-treated with Arsenic Trioxide] results in decreased expression of BCL2 mRNA; [Valproic Acid co-treated with Arsenic Trioxide] results in decreased expression of BCL2 protein; [Vorinostat co-treated with Arsenic Trioxide] results in decreased expression of BCL2 protein; Acetylcysteine inhibits the reaction [Arsenic Trioxide promotes the reaction [Resveratrol results in decreased expression of BCL2 protein]]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in decreased expression of BCL2 protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased expression of and affects the localization of BCL2 protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of BCL2 protein]; Acetylcysteine inhibits the reaction [Resveratrol promotes the reaction [Arsenic Trioxide results in decreased expression of BCL2 protein]]; Arsenic Trioxide inhibits the reaction [BCL2 protein binds to BAX protein binds to VDAC1 protein]; Arsenic Trioxide inhibits the reaction [BCL2 protein binds to BAX protein]; Arsenic Trioxide promotes the reaction [Genistein results in decreased expression of BCL2 protein]; Arsenic Trioxide promotes the reaction [Matrines results in decreased expression of BCL2 protein]; Arsenic Trioxide promotes the reaction [puerarin results in decreased expression of BCL2 mRNA]; Arsenic Trioxide promotes the reaction [Resveratrol results in decreased expression of BCL2 protein]; Arsenic Trioxide promotes the reaction [TGFB1 protein results in decreased expression of BCL2 protein]; Arsenic Trioxide results in decreased expression of and affects the localization of BCL2 protein; Arsenic Trioxide results in increased expression of and affects the localization of BCL2 protein; BCL2 inhibits the reaction [[Arsenic Trioxide co-treated with TNF protein] results in decreased expression of CFLAR protein]; BCL2 inhibits the reaction [[Arsenic Trioxide co-treated with TNF protein] results in increased activity of CASP8 protein]; BCL2 protein inhibits the reaction [[Arsenic Trioxide co-treated with lonidamine] results in increased cleavage of and results in increased activity of CASP8 protein]; BCL2 protein inhibits the reaction [[Arsenic Trioxide co-treated with Quercetin] results in increased cleavage of and results in increased activity of CASP8 protein]; BCL2 protein inhibits the reaction [Arsenic Trioxide inhibits the reaction [BCL2 protein binds to BAX protein]]; BCL2 protein inhibits the reaction [Arsenic Trioxide promotes the reaction [lonidamine results in increased cleavage of and results in increased activity of CASP9 protein]]; BCL2 protein inhibits the reaction [Arsenic Trioxide results in decreased expression of MYC mRNA]; BCL2 protein inhibits the reaction [Arsenic Trioxide results in increased activity of BAX protein]; BCL2 protein inhibits the reaction [Arsenic Trioxide results in increased activity of CASP3 protein]; BCL2 protein inhibits the reaction [lonidamine promotes the reaction [Arsenic Trioxide results in increased cleavage of and results in increased activity of CASP9 protein]]; Cycloheximide inhibits the reaction [Arsenic Trioxide results in increased expression of BCL2 protein]; Dactinomycin inhibits the reaction [Arsenic Trioxide results in increased expression of BCL2 protein]; Dithiothreitol inhibits the reaction [Arsenic Trioxide results in increased expression of BCL2 protein]; Gemcitabine promotes the reaction [Arsenic Trioxide results in decreased expression of BCL2 protein]; Genistein promotes the reaction [Arsenic Trioxide results in decreased expression of BCL2 protein]; GH1 protein promotes the reaction [Arsenic Trioxide results in decreased expression of BCL2 mRNA]; GRB10 protein promotes the reaction [[Arsenic Trioxide co-treated with apatinib] results in decreased expression of BCL2 protein]; HOMER3 protein affects the reaction [Arsenic Trioxide results in decreased expression of BCL2 protein]; ID1 protein inhibits the reaction [Arsenic Trioxide results in decreased expression of BCL2 protein]; MAPK14 mutant form inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of BCL2 protein]; MAPK8 mutant form inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of BCL2 protein]; MAPK9 mutant form inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of BCL2 protein]; MARVELD1 protein inhibits the reaction [Arsenic Trioxide results in decreased expression of BCL2 protein]; Matrines promotes the reaction [Arsenic Trioxide results in decreased expression of BCL2 protein]; NVP-BKM120 promotes the reaction [Arsenic Trioxide results in decreased expression of BCL2 mRNA]; pyrazolanthrone inhibits the reaction [Arsenic Trioxide results in decreased expression of BCL2 protein]; pyrazolanthrone inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of BCL2 protein]; Resveratrol promotes the reaction [Arsenic Trioxide results in decreased expression of BCL2 protein]; SB 203580 inhibits the reaction [Arsenic Trioxide affects the localization of BCL2 protein]; SB 203580 inhibits the reaction [Arsenic Trioxide results in increased expression of BCL2 mRNA]; SB 203580 inhibits the reaction [Arsenic Trioxide results in increased expression of BCL2 protein]; SB 203580 promotes the reaction [Arsenic Trioxide results in decreased expression of BCL2 protein]; Wortmannin inhibits the reaction [[Hydrogen Peroxide co-treated with Arsenic Trioxide] results in decreased expression of BCL2 protein] Arsenic Trioxide results in decreased expression of BCL2 mRNA; Arsenic Trioxide results in decreased expression of BCL2 protein BCL2 protein affects the susceptibility to Arsenic Trioxide Arsenic Trioxide affects the folding of BCL2 protein Arsenic Trioxide affects the expression of BCL2 mRNA; Arsenic Trioxide affects the expression of BCL2 protein BCL2 protein results in decreased susceptibility to Arsenic Trioxide; BCL2 results in decreased susceptibility to Arsenic Trioxide Arsenic Trioxide results in increased expression of BCL2 mRNA; Arsenic Trioxide results in increased expression of BCL2 protein Arsenic Trioxide results in increased degradation of BCL2 protein 18alpha,20beta-hydroxy-11-oxo-norolean-12-en-3beta-yl-2-O-beta-D-glucopyranurosyl-alpha-D-glucopyranosiduronate magnesium tetrahydrate inhibits the reaction [Arsenic Trioxide results in decreased expression of BCL2 protein]; [Genistein co-treated with Arsenic Trioxide] results in decreased expression of BCL2 protein; Arsenic Trioxide promotes the reaction [Drugs, Chinese Herbal results in decreased expression of BCL2 protein]; baicalin inhibits the reaction [Arsenic Trioxide results in decreased expression of BCL2 mRNA]; baicalin inhibits the reaction [Arsenic Trioxide results in decreased expression of BCL2 protein]; Drugs, Chinese Herbal promotes the reaction [Arsenic Trioxide results in decreased expression of BCL2 protein]; MIR34A affects the reaction [Arsenic Trioxide results in decreased expression of BCL2 protein]; Propranolol inhibits the reaction [Arsenic Trioxide results in decreased expression of BCL2 protein] BCL2 mutant form results in increased susceptibility to Arsenic Trioxide Arsenic Trioxide results in decreased expression of BCL2; Arsenic Trioxide results in decreased expression of BCL2 mRNA; Arsenic Trioxide results in decreased expression of BCL2 protein 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [salvianolic acid B inhibits the reaction [Arsenic Trioxide results in decreased expression of BCL2 protein]]; [alpha-Tocopherol co-treated with Ascorbic Acid] inhibits the reaction [Arsenic Trioxide results in decreased expression of BCL2 mRNA]; [Arsenic Trioxide results in increased abundance of Arsenic] which results in decreased expression of BCL2 protein; Apigenin inhibits the reaction [[Arsenic Trioxide results in increased abundance of Arsenic] which results in decreased expression of BCL2 protein]; crocin inhibits the reaction [Arsenic Trioxide results in decreased expression of BCL2 mRNA]; crocin inhibits the reaction [Arsenic Trioxide results in decreased expression of BCL2 protein]; Febuxostat inhibits the reaction [Arsenic Trioxide results in decreased expression of BCL2 protein]; ferrostatin-1 inhibits the reaction [Arsenic Trioxide results in decreased expression of BCL2 protein]; HTS 466284 inhibits the reaction [Arsenic Trioxide results in decreased expression of BCL2 protein]; Phloretin inhibits the reaction [Arsenic Trioxide results in decreased expression of BCL2 mRNA]; pifithrin inhibits the reaction [Arsenic Trioxide results in increased expression of BCL2 mRNA]; salvianolic acid A inhibits the reaction [Arsenic Trioxide results in decreased expression of BCL2 protein]; salvianolic acid B inhibits the reaction [Arsenic Trioxide results in decreased expression of BCL2 protein]; Taurine inhibits the reaction [Arsenic Trioxide results in decreased expression of BCL2 protein]; trans-sodium crocetinate inhibits the reaction [Arsenic Trioxide results in decreased expression of BCL2 protein]
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CTD |
PMID:8704214 PMID:9129041 PMID:9716575 PMID:9734658 PMID:10340400 PMID:10648417 PMID:10712780 PMID:10721769 PMID:10850458 PMID:11027660 PMID:11135700 PMID:11589617 PMID:11739184 PMID:11775218 PMID:11780464 PMID:12168106 PMID:12181429 PMID:12429934 PMID:12490120 PMID:12725324 PMID:12845720 PMID:12859871 PMID:12883267 PMID:12962562 PMID:12975549 PMID:14642526 PMID:14703445 PMID:15142122 PMID:15352174 PMID:15493360 PMID:15622746 PMID:15735709 PMID:15761769 PMID:15781666 PMID:15844663 PMID:15894607 PMID:16007134 PMID:16010437 PMID:16105982 PMID:16166054 PMID:16818652 PMID:16867262 PMID:16904648 PMID:16966277 PMID:17374990 PMID:17487067 PMID:17673311 PMID:18022205 PMID:18349030 PMID:18357729 PMID:18359480 PMID:18412143 PMID:18539383 PMID:18618274 PMID:18718063 PMID:18726487 PMID:19208092 PMID:19260322 PMID:19468689 PMID:19489279 PMID:19695276 PMID:19771260 PMID:20200477 PMID:20219070 PMID:20377131 PMID:20403207 PMID:20416161 PMID:20435036 PMID:20458559 PMID:20471514 PMID:20723295 PMID:20950636 PMID:21061466 PMID:21078540 PMID:21145380 PMID:21418039 PMID:21473291 PMID:21565247 PMID:21594580 PMID:21889928 PMID:21969006 PMID:22519831 PMID:22590507 PMID:22949821 PMID:22959511 PMID:23201927 PMID:23382965 PMID:23542815 PMID:23700110 PMID:23721794 PMID:23725168 PMID:23851143 PMID:23861973 PMID:23980369 PMID:24126434 PMID:24157283 PMID:24377552 PMID:24466103 PMID:24738333 PMID:24944602 PMID:24993472 PMID:25110043 PMID:25174355 PMID:25335113 PMID:25416439 PMID:25787108 PMID:25815518 PMID:25945059 PMID:25972196 PMID:26110921 PMID:26772155 PMID:27189198 PMID:27430728 PMID:28391263 PMID:28587418 PMID:29274334 PMID:29297235 PMID:29610575 PMID:30012499 PMID:30091188 PMID:30145367 PMID:30316766 PMID:30333888 PMID:30472098 PMID:30551535 PMID:31079498 PMID:31205918 PMID:31539632 PMID:32096187 PMID:32642412 PMID:32645343 PMID:32781346 PMID:32919218 PMID:32920515 PMID:33173984 PMID:33603344 PMID:33846815 PMID:34025784 PMID:34037972 PMID:34303041 PMID:34333357 PMID:34675983 PMID:35030298 PMID:35088608 PMID:35195477 PMID:35317438 PMID:36352148 PMID:36400307 PMID:36442592 PMID:36707890 PMID:37689273 PMID:37730986 PMID:39223679 More...
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NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900
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| G
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Bcl2a1
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BCL2-related protein A1
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decreases expression multiple interactions increases expression
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ISO EXP
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Arsenic Trioxide results in decreased expression of BCL2A1 mRNA [Tretinoin co-treated with Arsenic Trioxide co-treated with Butyrates] results in increased expression of BCL2A1 mRNA; [Tretinoin co-treated with Arsenic Trioxide co-treated with hexamethylene bisacetamide] results in increased expression of BCL2A1 mRNA; [Tretinoin co-treated with Arsenic Trioxide] results in increased expression of BCL2A1 mRNA; Arsenic Trioxide inhibits the reaction [Tretinoin results in increased expression of BCL2A1A protein] Arsenic Trioxide results in increased expression of BCL2A1 mRNA Arsenic Trioxide results in decreased expression of BCL2A1D mRNA
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CTD |
PMID:10673743 PMID:11133770 PMID:12130515 PMID:15894607 PMID:17530438 PMID:19128835 PMID:19730151 More...
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NCBI chr 8:98,596,806...98,604,890
Ensembl chr 8:98,596,650...98,604,890
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| G
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Bcl2l1
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Bcl2-like 1
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affects expression affects response to substance multiple interactions increases expression decreases expression
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EXP ISO
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Arsenic Trioxide affects the expression of BCL2L1 protein BCL2L1 protein affects the susceptibility to Arsenic Trioxide 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [salvianolic acid B inhibits the reaction [Arsenic Trioxide results in decreased expression of BCL2L1 protein]]; salvianolic acid A inhibits the reaction [Arsenic Trioxide results in decreased expression of BCL2L1 protein]; salvianolic acid B inhibits the reaction [Arsenic Trioxide results in decreased expression of BCL2L1 protein] Arsenic Trioxide results in increased expression of BCL2L1 mRNA; Arsenic Trioxide results in increased expression of BCL2L1 protein [Genistein co-treated with Arsenic Trioxide] results in decreased expression of BCL2L1 protein; Arsenic Trioxide promotes the reaction [Drugs, Chinese Herbal results in decreased expression of BCL2L1 protein]; Drugs, Chinese Herbal promotes the reaction [Arsenic Trioxide results in decreased expression of BCL2L1 protein] Arsenic Trioxide results in decreased expression of BCL2L1 mRNA; Arsenic Trioxide results in decreased expression of BCL2L1 protein [Arsenic Trioxide co-treated with epigallocatechin gallate] results in decreased expression of BCL2L1 protein; [Arsenic Trioxide co-treated with Ethacrynic Acid] results in increased expression of BCL2L1 protein; [Arsenic Trioxide co-treated with IL24 protein] results in decreased expression of BCL2L1; [Arsenic Trioxide co-treated with Quercetin] results in decreased expression of BCL2L1 protein; [BIBR 1532 co-treated with Arsenic Trioxide] affects the expression of BCL2L1 mRNA; [Genistein co-treated with Arsenic Trioxide] results in decreased expression of BCL2L1 protein; [paricalcitol co-treated with Arsenic Trioxide] results in decreased expression of BCL2L1; [Sulindac co-treated with Arsenic Trioxide] results in increased phosphorylation of BCL2L1 protein; Acetylcysteine inhibits the reaction [[Sulindac co-treated with Arsenic Trioxide] results in increased phosphorylation of BCL2L1 protein]; allicin inhibits the reaction [Arsenic Trioxide results in decreased expression of BCL2L1 protein]; Genistein promotes the reaction [Arsenic Trioxide results in decreased expression of BCL2L1 protein]; Hydrogen Peroxide inhibits the reaction [Arsenic Trioxide results in decreased expression of BCL2L1 protein]; MAPK8 affects the reaction [[Sulindac co-treated with Arsenic Trioxide] results in increased phosphorylation of BCL2L1 protein]; MMP9 protein inhibits the reaction [Arsenic Trioxide results in decreased expression of BCL2L1 protein]; pyrazolanthrone inhibits the reaction [[Sulindac co-treated with Arsenic Trioxide] results in increased phosphorylation of BCL2L1 protein]; Wortmannin inhibits the reaction [Hydrogen Peroxide inhibits the reaction [Arsenic Trioxide results in decreased expression of BCL2L1 protein]]
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CTD |
PMID:10648417 PMID:11468182 PMID:11739184 PMID:12480548 PMID:12883035 PMID:15142122 PMID:15665116 PMID:15781666 PMID:16105982 PMID:16360329 PMID:17530438 PMID:18281123 PMID:18349030 PMID:18359480 PMID:18546268 PMID:19730151 PMID:19763917 PMID:20950636 PMID:21078540 PMID:21889928 PMID:23082001 PMID:23201927 PMID:23337567 PMID:23770046 PMID:23861973 PMID:24466103 PMID:24944602 PMID:24956101 PMID:25335113 PMID:25416439 PMID:27561292 PMID:28391263 PMID:28454374 PMID:28587418 PMID:29738779 PMID:30472098 PMID:32645343 PMID:34413873 More...
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NCBI chr 3:161,713,777...161,764,844
Ensembl chr 3:161,745,540...161,764,907 Ensembl chr 1:161,745,540...161,764,907
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| G
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Bcl2l10
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Bcl2-like 10
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decreases expression
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EXP
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Arsenic Trioxide results in decreased expression of BCL2L10 mRNA
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CTD |
PMID:19730151 |
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NCBI chr 8:84,987,833...84,993,878
Ensembl chr 8:84,987,833...84,993,872
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| G
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Bcl2l11
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Bcl2-like 11
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increases expression multiple interactions increases degradation affects expression
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ISO
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Arsenic Trioxide results in increased expression of BCL2L11 mRNA; Arsenic Trioxide results in increased expression of BCL2L11 protein 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Arsenic Trioxide results in increased degradation of BCL2L11 protein]; [Arsenic Trioxide co-treated with Curcumin] results in increased expression of BCL2L11 protein; [Arsenic Trioxide co-treated with VS-5584] results in increased expression of BCL2L11 mRNA; [Arsenic Trioxide results in increased expression of BCL2L11 protein] which results in decreased phosphorylation of AKT1 protein; Arsenic Trioxide inhibits the reaction [BCL2L11 protein binds to MCL1 protein]; Arsenic Trioxide inhibits the reaction [Tunicamycin results in increased expression of BCL2L11 protein]; Arsenic Trioxide promotes the reaction [Matrines results in increased expression of BCL2L11 protein]; BCL2L11 mutant form inhibits the reaction [Arsenic Trioxide results in increased cleavage of CASP3 protein]; BCL2L11 mutant form inhibits the reaction [Arsenic Trioxide results in increased cleavage of CASP9 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Arsenic Trioxide results in increased degradation of BCL2L11 protein]; Bortezomib inhibits the reaction [Arsenic Trioxide results in increased degradation of BCL2L11 protein]; Matrines promotes the reaction [Arsenic Trioxide results in increased expression of BCL2L11 protein]; MMP9 protein inhibits the reaction [Arsenic Trioxide inhibits the reaction [BCL2L11 protein binds to MCL1 protein]]; MMP9 protein inhibits the reaction [Arsenic Trioxide results in increased expression of BCL2L11 protein] Arsenic Trioxide affects the expression of BCL2L11 protein
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CTD |
PMID:17203211 PMID:17530438 PMID:21655183 PMID:23700110 PMID:24956101 PMID:27430728 PMID:29574283 PMID:36509116 More...
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NCBI chr 3:135,820,042...135,857,330
Ensembl chr 3:135,817,562...135,960,695
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| G
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Bcl2l12
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Bcl2 like 12
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multiple interactions
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ISO
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Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to BCL2L12 protein]
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CTD |
PMID:26598702 |
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NCBI chr 1:104,608,753...104,617,472
Ensembl chr 1:104,608,753...104,617,472
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| G
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Bcl2l14
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Bcl2-like 14
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increases expression decreases response to substance multiple interactions
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ISO
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Arsenic Trioxide results in increased expression of BCL2L14 mRNA BCL2L14 protein results in decreased susceptibility to Arsenic Trioxide [sanguinarine co-treated with Arsenic Trioxide] results in increased expression of BCL2L14 mRNA
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CTD |
PMID:20458559 PMID:20707922 PMID:24345465 |
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NCBI chr 4:168,948,919...168,989,450
Ensembl chr 4:168,948,946...168,990,079
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| G
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Bcl2l2
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Bcl2-like 2
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increases expression decreases expression multiple interactions
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ISO EXP
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Arsenic Trioxide results in increased expression of BCL2L2 protein Arsenic Trioxide results in decreased expression of BCL2L2 mRNA [Arsenic Trioxide co-treated with Curcumin] affects the expression of BCL2L2 protein
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CTD |
PMID:19730151 PMID:27430728 |
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NCBI chr15:32,326,686...32,337,834
Ensembl chr15:32,326,020...32,335,379
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| G
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Bcl3
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BCL3, transcription coactivator
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multiple interactions
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ISO
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[Arsenic Trioxide co-treated with Bortezomib] results in decreased expression of BCL3 mRNA
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CTD |
PMID:20471514 |
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NCBI chr 1:88,599,321...88,613,555
Ensembl chr 1:88,599,321...88,614,368
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| G
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Bcl6
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BCL6, transcription repressor
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increases expression
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ISO
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Arsenic Trioxide results in increased expression of BCL6 mRNA
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CTD |
PMID:24356939 |
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NCBI chr11:90,358,753...90,382,049
Ensembl chr11:90,358,753...90,382,047
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| G
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Bcl7a
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BAF chromatin remodeling complex subunit BCL7A
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increases expression
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ISO
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Arsenic Trioxide results in increased expression of BCL7A mRNA
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CTD |
PMID:20458559 |
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NCBI chr12:38,872,851...38,904,770
Ensembl chr12:38,872,851...38,904,770
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| G
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Bcl7b
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BAF chromatin remodeling complex subunit BCL7B
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increases expression
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ISO
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Arsenic Trioxide results in increased expression of BCL7B mRNA
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CTD |
PMID:39716349 |
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NCBI chr12:27,133,412...27,146,631
Ensembl chr12:27,133,412...27,146,636
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| G
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Bco1
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beta-carotene oxygenase 1
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decreases expression
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ISO
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Arsenic Trioxide results in decreased expression of BCO1 mRNA
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CTD |
PMID:15761015 |
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NCBI chr19:62,058,061...62,094,923
Ensembl chr19:62,058,089...62,094,917
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| G
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Bcr
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BCR activator of RhoGEF and GTPase
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multiple interactions increases degradation increases expression decreases expression
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ISO
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Arsenic Trioxide promotes the reaction [CTSB protein results in increased degradation of BCR protein mutant form]; Arsenic Trioxide promotes the reaction [SQSTM1 protein results in increased localization of BCR protein mutant form]; Arsenic Trioxide results in decreased expression of [BCR protein mutant form binds to ABL1 protein mutant form]; ATG7 protein promotes the reaction [Arsenic Trioxide results in increased degradation of BCR protein mutant form]; BECN1 protein promotes the reaction [Arsenic Trioxide results in increased degradation of BCR protein mutant form]; SQSTM1 protein promotes the reaction [Arsenic Trioxide results in increased degradation of BCR protein mutant form] Arsenic Trioxide results in increased expression of BCR mRNA Arsenic Trioxide results in decreased expression of BCR mRNA; Arsenic Trioxide results in decreased expression of BCR protein mutant form
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CTD |
PMID:14633726 PMID:20458559 PMID:22330069 PMID:22521957 PMID:22898604 PMID:24129092 PMID:39716349 More...
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NCBI chr20:13,468,732...13,596,333
Ensembl chr20:13,468,732...13,596,333
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| G
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Bdh1
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3-hydroxybutyrate dehydrogenase 1
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decreases expression increases expression
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ISO
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Arsenic Trioxide results in decreased expression of BDH1 mRNA Arsenic Trioxide results in increased expression of BDH1 mRNA
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CTD |
PMID:22521957 PMID:39716349 |
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NCBI chr11:82,806,125...82,848,133
Ensembl chr11:82,807,503...82,842,636
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| G
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Bdh2
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3-hydroxybutyrate dehydrogenase 2
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multiple interactions
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ISO
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Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to BDH2 protein]
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CTD |
PMID:26598702 |
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NCBI chr 2:226,376,346...226,397,010
Ensembl chr 2:226,376,356...226,397,006
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| G
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Bdkrb2
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bradykinin receptor B2
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increases expression
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ISO
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Arsenic Trioxide results in increased expression of BDKRB2 mRNA
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CTD |
PMID:37969188 |
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NCBI chr 6:130,237,055...130,267,205
Ensembl chr 6:130,237,255...130,267,209
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| G
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Bdnf
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brain-derived neurotrophic factor
|
decreases expression multiple interactions
|
ISO EXP
|
Arsenic Trioxide results in decreased expression of BDNF protein Arsenic Trioxide promotes the reaction [Reserpine results in decreased expression of BDNF protein]; Resveratrol inhibits the reaction [Arsenic Trioxide results in decreased expression of BDNF protein] Arsenic Trioxide results in decreased expression of BDNF mRNA
|
CTD |
PMID:16711005 PMID:26114099 PMID:29223816 PMID:34050381 |
|
NCBI chr 3:116,619,633...116,670,212
Ensembl chr 3:116,619,633...116,670,657
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| G
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Becn1
|
beclin 1
|
increases expression multiple interactions decreases expression
|
ISO EXP
|
Arsenic Trioxide results in increased expression of BECN1; Arsenic Trioxide results in increased expression of BECN1 mRNA; Arsenic Trioxide results in increased expression of BECN1 protein 3-methyladenine inhibits the reaction [Arsenic Trioxide results in increased expression of BECN1]; Arsenic Trioxide promotes the reaction [ABL1 protein mutant form binds to BECN1 protein]; BECN1 protein promotes the reaction [Arsenic Trioxide results in increased degradation of BCR protein mutant form]; Cycloheximide inhibits the reaction [Arsenic Trioxide results in increased expression of BECN1 protein] 3-methyladenine inhibits the reaction [Arsenic Trioxide results in increased expression of BECN1 mRNA]; [Cisplatin co-treated with Arsenic Trioxide] results in increased expression of BECN1 protein ferrostatin-1 inhibits the reaction [Arsenic Trioxide results in decreased expression of BECN1 protein]
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CTD |
PMID:16882451 PMID:20200477 PMID:21594580 PMID:22519831 PMID:22898604 PMID:25110043 PMID:30032600 PMID:30225639 PMID:31149761 PMID:32112876 PMID:32781346 PMID:33070465 PMID:33462182 PMID:35195477 More...
|
|
NCBI chr10:86,731,649...86,747,002
Ensembl chr10:86,731,650...86,747,002
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| G
|
Best1
|
bestrophin 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of BEST1 mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr 1:216,054,395...216,071,012
Ensembl chr 1:216,054,395...216,070,974
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|
| G
|
Bfar
|
bifunctional apoptosis regulator
|
decreases expression increases expression
|
EXP ISO
|
Arsenic Trioxide results in decreased expression of BFAR mRNA Arsenic Trioxide results in increased expression of BFAR mRNA
|
CTD |
PMID:19730151 PMID:20458559 PMID:35676786 |
|
NCBI chr10:2,059,189...2,092,207
Ensembl chr10:2,059,058...2,094,183
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| G
|
Bglap
|
bone gamma-carboxyglutamate protein
|
decreases expression multiple interactions
|
EXP
|
Arsenic Trioxide results in decreased expression of BGLAP; Arsenic Trioxide results in decreased expression of BGLAP mRNA 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Arsenic Trioxide results in decreased expression of BGLAP]
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CTD |
PMID:22465848 PMID:24531206 |
|
NCBI chr 2:176,136,341...176,137,318
Ensembl chr 2:176,136,341...176,137,318
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| G
|
Bgn
|
biglycan
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of BGN mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr X:156,348,633...156,360,797
Ensembl chr X:156,348,615...156,360,799
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|
| G
|
Bhlhe40
|
basic helix-loop-helix family, member e40
|
multiple interactions increases expression
|
ISO
|
[Tretinoin co-treated with Arsenic Trioxide] results in increased expression of BHLHE40 mRNA Arsenic Trioxide results in increased expression of BHLHE40 mRNA
|
CTD |
PMID:15761015 PMID:15894607 |
|
NCBI chr 4:143,174,450...143,180,150
Ensembl chr 4:143,174,048...143,180,783
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|
| G
|
Bhlhe41
|
basic helix-loop-helix family, member e41
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of BHLHE41 mRNA
|
CTD |
PMID:35676786 |
|
NCBI chr 4:180,565,003...180,569,415
Ensembl chr 4:180,565,003...180,569,355
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|
| G
|
Bid
|
BH3 interacting domain death agonist
|
decreases expression affects cleavage multiple interactions increases activity increases cleavage affects expression
|
ISO EXP
|
Arsenic Trioxide results in decreased expression of BID protein Arsenic Trioxide affects the cleavage of BID protein [Arsenic Trioxide co-treated with apatinib] results in increased expression of BID protein; [Arsenic Trioxide co-treated with Aprepitant] results in increased expression of BID mRNA; [Arsenic Trioxide co-treated with Curcumin] results in decreased expression of BID protein; [Arsenic Trioxide co-treated with Curcumin] results in increased expression of BID protein; [Arsenic Trioxide co-treated with esculetin] results in increased cleavage of BID protein; [Arsenic Trioxide co-treated with lonidamine] results in increased cleavage of and results in increased activity of BID protein; [Arsenic Trioxide co-treated with NVP-BKM120] results in increased expression of BID mRNA; [Arsenic Trioxide co-treated with Quercetin] results in increased cleavage of BID protein; [Arsenic Trioxide co-treated with TNF protein] results in increased cleavage of and results in increased activity of BID protein; Arsenic Trioxide results in increased cleavage of and results in increased activity of BID protein; Curcumin promotes the reaction [Arsenic Trioxide results in increased activity of BID protein]; Deoxyglucose promotes the reaction [Arsenic Trioxide results in increased cleavage of and results in increased activity of BID protein]; Genistein promotes the reaction [Arsenic Trioxide results in increased cleavage of and results in increased activity of BID protein]; pyrazolanthrone promotes the reaction [Arsenic Trioxide results in increased cleavage of BID protein]; TP53 protein inhibits the reaction [Arsenic Trioxide results in increased cleavage of and results in increased activity of BID protein]; U 0126 promotes the reaction [Arsenic Trioxide results in increased cleavage of BID protein] Arsenic Trioxide promotes the reaction [Drugs, Chinese Herbal results in increased cleavage of BID protein] Arsenic Trioxide affects the expression of BID protein
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CTD |
PMID:10648417 PMID:12851490 PMID:15131059 PMID:15665116 PMID:16972261 PMID:17673311 PMID:18359480 PMID:18546268 PMID:18618274 PMID:19364129 PMID:19428345 PMID:20605902 PMID:21418039 PMID:21889928 PMID:23041229 PMID:25174355 PMID:25574600 PMID:27430728 PMID:28587418 PMID:30145367 PMID:31539632 PMID:39223679 More...
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|
NCBI chr 4:155,785,366...155,808,775
Ensembl chr 4:155,785,377...155,808,275
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|
| G
|
Bik
|
BCL2-interacting killer
|
multiple interactions increases expression
|
ISO EXP
|
[sanguinarine co-treated with Arsenic Trioxide] results in increased expression of BIK mRNA Arsenic Trioxide results in increased expression of BIK mRNA
|
CTD |
PMID:19730151 PMID:24345465 |
|
NCBI chr 7:116,552,303...116,571,317
Ensembl chr 7:116,552,303...116,571,317
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|
| G
|
Birc2
|
baculoviral IAP repeat-containing 2
|
multiple interactions decreases expression
|
ISO
|
[Arsenic Trioxide co-treated with NVP-BKM120] results in decreased expression of BIRC2 mRNA; [NVP-BKM120 co-treated with Arsenic Trioxide] results in decreased expression of BIRC2 mRNA; Arsenic Trioxide promotes the reaction [Aprepitant results in decreased expression of BIRC2 mRNA] Arsenic Trioxide results in decreased expression of BIRC2 mRNA
|
CTD |
PMID:30145367 PMID:30316766 PMID:31539632 |
|
NCBI chr 8:13,253,697...13,273,672
Ensembl chr 8:13,253,706...13,271,911
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|
| G
|
Birc3
|
baculoviral IAP repeat-containing 3
|
decreases expression increases expression multiple interactions
|
ISO
|
Arsenic Trioxide results in decreased expression of BIRC3 mRNA; Arsenic Trioxide results in decreased expression of BIRC3 protein Arsenic Trioxide results in increased expression of BIRC3 mRNA [Arsenic Trioxide co-treated with Curcumin] results in decreased expression of BIRC3 protein; [Arsenic Trioxide co-treated with VS-5584] results in decreased expression of BIRC3 mRNA; [BIBR 1532 co-treated with Arsenic Trioxide] affects the expression of BIRC3 mRNA; Arsenic Trioxide promotes the reaction [Aprepitant results in decreased expression of BIRC3 mRNA]; NVP-BKM120 promotes the reaction [Arsenic Trioxide results in decreased expression of BIRC3 mRNA]
|
CTD |
PMID:19763917 PMID:24356939 PMID:27430728 PMID:29574283 PMID:30145367 PMID:30316766 PMID:32645343 PMID:38275666 More...
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|
NCBI chr 8:13,285,702...13,313,329
Ensembl chr 8:13,285,703...13,298,590
|
|
| G
|
Birc5
|
baculoviral IAP repeat-containing 5
|
decreases expression increases expression affects response to substance multiple interactions affects expression decreases response to substance
|
ISO
|
Arsenic Trioxide results in decreased expression of BIRC5 protein Arsenic Trioxide results in decreased expression of BIRC5; Arsenic Trioxide results in decreased expression of BIRC5 mRNA; Arsenic Trioxide results in decreased expression of BIRC5 protein Arsenic Trioxide results in increased expression of BIRC5 mRNA; Arsenic Trioxide results in increased expression of BIRC5 protein BIRC5 protein affects the susceptibility to Arsenic Trioxide Arsenic Trioxide promotes the reaction [Drugs, Chinese Herbal results in decreased expression of BIRC5 protein]; Drugs, Chinese Herbal promotes the reaction [Arsenic Trioxide results in decreased expression of BIRC5 protein] Arsenic Trioxide affects the expression of BIRC5 mRNA BIRC5 protein results in decreased susceptibility to Arsenic Trioxide 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one promotes the reaction [Arsenic Trioxide results in decreased expression of BIRC5 protein]; [Arsenic Trioxide co-treated with Aprepitant] results in decreased expression of BIRC5 mRNA; [Arsenic Trioxide co-treated with Calcitriol] results in decreased expression of BIRC5 mRNA; [Arsenic Trioxide co-treated with Calcitriol] results in decreased expression of BIRC5 protein; [Arsenic Trioxide co-treated with Curcumin] results in decreased expression of BIRC5 protein; [Arsenic Trioxide co-treated with Doxorubicin co-treated with Magnetite Nanoparticles analog] affects the expression of BIRC5 mRNA; [Arsenic Trioxide co-treated with Doxorubicin co-treated with Magnetite Nanoparticles analog] affects the expression of BIRC5 protein; [Arsenic Trioxide co-treated with Ethacrynic Acid] results in decreased expression of BIRC5 protein; [Arsenic Trioxide co-treated with NVP-BKM120] results in decreased expression of BIRC5 mRNA; [Arsenic Trioxide co-treated with Oxygen deficiency] results in decreased expression of BIRC5 mRNA; [Arsenic Trioxide co-treated with Oxygen deficiency] results in decreased expression of BIRC5 protein; [Arsenic Trioxide co-treated with sepantronium] results in decreased expression of BIRC5 protein; [Arsenic Trioxide results in increased susceptibility to PD 173074] which results in decreased expression of BIRC5 protein; [BIBR 1532 co-treated with Arsenic Trioxide] affects the expression of BIRC5 mRNA; [Erlotinib Hydrochloride co-treated with Arsenic Trioxide] results in decreased expression of BIRC5 mRNA; [NVP-BKM120 co-treated with Arsenic Trioxide] results in decreased expression of BIRC5 mRNA; [ruxolitinib co-treated with Arsenic Trioxide] results in decreased expression of BIRC5 mRNA; [Silybin co-treated with Arsenic Trioxide] results in decreased expression of BIRC5 mRNA; [Sulindac co-treated with Arsenic Trioxide] results in decreased expression of BIRC5 protein; Arsenic Trioxide promotes the reaction [Matrines results in decreased expression of BIRC5 protein]; Arsenic Trioxide promotes the reaction [puerarin results in decreased expression of BIRC5 mRNA]; GH1 protein promotes the reaction [Arsenic Trioxide results in decreased expression of BIRC5 mRNA]; Matrines promotes the reaction [Arsenic Trioxide results in decreased expression of BIRC5 protein]; Poly I-C promotes the reaction [Arsenic Trioxide results in decreased expression of BIRC5 protein]; pyrazolanthrone inhibits the reaction [Arsenic Trioxide results in decreased expression of BIRC5 protein]; SB 203580 inhibits the reaction [Arsenic Trioxide results in decreased expression of BIRC5 protein]; U 0126 inhibits the reaction [Arsenic Trioxide results in decreased expression of BIRC5 protein]
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CTD |
PMID:15587394 PMID:16328441 PMID:16638212 PMID:17869043 PMID:18088464 PMID:18281123 PMID:19763917 PMID:19825857 PMID:20416161 PMID:20435036 PMID:20635649 PMID:21418039 PMID:21473291 PMID:21594580 PMID:21969006 PMID:22944098 PMID:23082001 PMID:23700110 PMID:23851143 PMID:24738333 PMID:26705709 PMID:27039805 PMID:27430728 PMID:27770503 PMID:27794399 PMID:28587418 PMID:29274334 PMID:30012499 PMID:30145367 PMID:30316766 PMID:31539632 PMID:32305283 PMID:32645343 PMID:34025784 PMID:36442592 PMID:38275666 More...
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|
NCBI chr10:103,567,369...103,580,069
Ensembl chr10:103,572,080...103,582,155
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|
| G
|
Birc7
|
baculoviral IAP repeat-containing 7
|
increases expression multiple interactions
|
ISO
|
Arsenic Trioxide results in increased expression of BIRC7 protein [Arsenic Trioxide co-treated with Curcumin] results in increased expression of BIRC7 protein; Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to BIRC7 protein]; Arsenic Trioxide promotes the reaction [Bortezomib results in decreased expression of BIRC7 mRNA] Arsenic Trioxide results in increased expression of BIRC7 mRNA
|
CTD |
PMID:21867610 PMID:26598702 PMID:27430728 PMID:39716349 |
|
NCBI chr 3:188,425,392...188,430,174
Ensembl chr 3:188,425,392...188,430,174
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|
| G
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Blvrb
|
biliverdin reductase B
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of BLVRB mRNA
|
CTD |
PMID:15725085 PMID:27829220 PMID:29633893 |
|
NCBI chr 1:91,866,258...91,883,921
Ensembl chr 1:91,866,258...91,884,225
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|
| G
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Blzf1
|
basic leucine zipper nuclear factor 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of BLZF1 mRNA
|
CTD |
PMID:15761015 |
|
NCBI chr13:79,174,898...79,190,116
Ensembl chr13:79,174,902...79,190,116
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|
| G
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Bmf
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Bcl2 modifying factor
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of BMF mRNA
|
CTD |
PMID:19417148 |
|
NCBI chr 3:125,953,466...125,974,087
Ensembl chr 3:125,953,466...125,974,258
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|
| G
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Bmi1
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BMI1 proto-oncogene, polycomb ring finger
|
decreases response to substance
|
ISO
|
BMI1 protein results in decreased susceptibility to Arsenic Trioxide
|
CTD |
PMID:24571310 |
|
NCBI chr17:86,240,683...86,250,044
Ensembl chr17:86,243,491...86,250,024
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|
| G
|
Bmp1
|
bone morphogenetic protein 1
|
multiple interactions
|
ISO
|
[Arsenic Trioxide co-treated with apatinib] results in decreased expression of BMP1 mRNA
|
CTD |
PMID:39223679 |
|
NCBI chr15:51,961,310...52,005,597
Ensembl chr15:51,961,310...52,005,485
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|
| G
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Bmp2
|
bone morphogenetic protein 2
|
multiple interactions decreases expression
|
EXP
|
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Arsenic Trioxide results in decreased expression of BMP2]
|
CTD |
PMID:24531206 |
|
NCBI chr 3:141,264,648...141,275,416
Ensembl chr 3:141,264,646...141,274,760
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|
| G
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Bmpr1a
|
bone morphogenetic protein receptor type 1A
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of BMPR1A mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr16:9,740,751...9,786,861
Ensembl chr16:9,742,875...9,786,861
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| G
|
Bmpr2
|
bone morphogenetic protein receptor type 2
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of BMPR2 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 9:68,685,942...68,801,353
Ensembl chr 9:68,685,988...68,801,350
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|
| G
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Bnc2
|
basonuclin zinc finger protein 2
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of BNC2 mRNA
|
CTD |
PMID:26705709 |
|
NCBI chr 5:103,724,934...104,061,890
Ensembl chr 5:103,724,934...104,125,428
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|
| G
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Bnip3
|
BCL2 interacting protein 3
|
multiple interactions increases expression decreases expression increases response to substance
|
ISO EXP
|
[Arsenic Trioxide co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] results in decreased expression of BNIP3 mRNA; Arsenic Trioxide inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of BNIP3 mRNA] Arsenic Trioxide results in increased expression of BNIP3 mRNA; Arsenic Trioxide results in increased expression of BNIP3 protein Arsenic Trioxide results in decreased expression of BNIP3 mRNA BNIP3 protein results in increased susceptibility to Arsenic Trioxide
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CTD |
PMID:15592527 PMID:17530438 PMID:19730151 PMID:25446377 |
|
NCBI chr 1:203,137,778...203,154,962
Ensembl chr 1:203,137,778...203,154,962
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|
| G
|
Bnip3l
|
BCL2 interacting protein 3 like
|
increases expression multiple interactions
|
ISO
|
Arsenic Trioxide results in increased expression of BNIP3L mRNA; Arsenic Trioxide results in increased expression of BNIP3L protein [sanguinarine co-treated with Arsenic Trioxide] results in increased expression of BNIP3L mRNA
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CTD |
PMID:15592527 PMID:24345465 |
|
NCBI chr15:45,350,081...45,373,213
Ensembl chr15:45,334,537...45,373,282
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|
| G
|
Boc
|
BOC cell adhesion associated, oncogene regulated
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of BOC mRNA
|
CTD |
PMID:26705709 |
|
NCBI chr11:69,628,703...69,704,009
Ensembl chr11:69,628,660...69,704,004
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|
| G
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Bod1l1
|
biorientation of chromosomes in cell division 1-like 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of BOD1L1 mRNA
|
CTD |
PMID:26705709 |
|
NCBI chr14:73,320,880...73,375,662
Ensembl chr14:73,320,832...73,375,658
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|
| G
|
Bop1
|
BOP1 ribosomal biogenesis factor
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of BOP1 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 7:110,052,716...110,076,529
Ensembl chr 7:110,052,720...110,076,529
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|
| G
|
Bpi
|
bactericidal/permeability-increasing protein
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of BPI mRNA
|
CTD |
PMID:15761015 PMID:20458559 |
|
NCBI chr 3:167,329,513...167,356,217
Ensembl chr 3:167,329,530...167,356,396
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|
| G
|
Braf
|
B-Raf proto-oncogene, serine/threonine kinase
|
decreases expression increases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of BRAF mRNA Arsenic Trioxide results in increased expression of BRAF mRNA
|
CTD |
PMID:24831965 PMID:29633893 |
|
NCBI chr 4:69,329,772...69,476,931
Ensembl chr 4:69,342,813...69,476,931
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|
| G
|
Brca1
|
BRCA1, DNA repair associated
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of BRCA1 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr10:86,917,693...86,978,012
Ensembl chr10:86,917,693...86,977,763
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|
| G
|
Brca2
|
BRCA2, DNA repair associated
|
multiple interactions decreases expression
|
ISO
|
[Arsenic Trioxide co-treated with Bortezomib] results in increased expression of BRCA2 mRNA Arsenic Trioxide results in decreased expression of BRCA2 mRNA
|
CTD |
PMID:20471514 PMID:25913414 |
|
NCBI chr12:4,895,092...4,939,340
Ensembl chr12:4,895,447...4,936,194
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|
| G
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Brd8
|
bromodomain containing 8
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of BRD8 mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr18:26,455,824...26,504,106
Ensembl chr18:26,455,512...26,504,006
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|
| G
|
Brinp1
|
BMP/retinoic acid inducible neural specific 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of BRINP1 mRNA
|
CTD |
PMID:15761015 |
|
NCBI chr 5:87,363,621...87,565,580
Ensembl chr 5:87,364,050...87,508,256
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|
| G
|
Brpf1
|
bromodomain and PHD finger containing, 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of BRPF1 mRNA
|
CTD |
PMID:29633893 |
|
NCBI chr 4:148,011,977...148,028,431
Ensembl chr 4:148,011,931...148,028,424
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|
| G
|
Bsg
|
basigin
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of BSG mRNA; Arsenic Trioxide results in decreased expression of BSG protein
|
CTD |
PMID:23232515 |
|
NCBI chr 7:10,643,788...10,651,005
Ensembl chr 7:10,643,789...10,651,005
|
|
| G
|
Bst2
|
bone marrow stromal cell antigen 2
|
multiple interactions
|
ISO
|
[Tretinoin co-treated with Arsenic Trioxide] results in increased expression of BST2 mRNA
|
CTD |
PMID:15894607 |
|
NCBI chr16:18,250,593...18,254,967
Ensembl chr16:18,251,847...18,254,967
|
|
| G
|
Btaf1
|
B-TFIID TATA-box binding protein associated factor 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of BTAF1 mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr 1:244,065,728...244,156,457
Ensembl chr 1:244,065,743...244,156,457
|
|
| G
|
Btbd2
|
BTB domain containing 2
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of BTBD2 mRNA
|
CTD |
PMID:15725085 |
|
NCBI chr 7:9,710,392...9,726,032
Ensembl chr 7:9,712,269...9,726,032
|
|
| G
|
Btbd3
|
BTB domain containing 3
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of BTBD3 mRNA
|
CTD |
PMID:15725085 |
|
NCBI chr 3:146,044,053...146,074,189
Ensembl chr 3:146,044,096...146,074,635
|
|
| G
|
Btf3
|
basic transcription factor 3
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of BTF3 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 2:31,394,010...31,401,138
Ensembl chr 2:31,394,011...31,401,125 Ensembl chr13:31,394,011...31,401,125
|
|
| G
|
Btg1
|
BTG anti-proliferation factor 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of BTG1 mRNA
|
CTD |
PMID:18231732 |
|
NCBI chr 7:33,228,149...33,230,406
Ensembl chr 7:33,227,833...33,230,406
|
|
| G
|
Btg2
|
BTG anti-proliferation factor 2
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of BTG2 mRNA
|
CTD |
PMID:20458559 PMID:22521957 |
|
NCBI chr13:48,083,931...48,087,690
Ensembl chr13:48,083,931...48,087,690
|
|
| G
|
Btk
|
Bruton tyrosine kinase
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of BTK mRNA
|
CTD |
PMID:23911876 |
|
NCBI chr X:102,016,070...102,055,448
Ensembl chr X:102,016,074...102,055,143
|
|
| G
|
Bub1b
|
BUB1 mitotic checkpoint serine/threonine kinase B
|
increases phosphorylation multiple interactions
|
ISO
|
Arsenic Trioxide results in increased phosphorylation of BUB1B protein 17-(dimethylaminoethylamino)-17-demethoxygeldanamycin promotes the reaction [Arsenic Trioxide results in increased phosphorylation of BUB1B protein]; [Arsenic Trioxide co-treated with Paclitaxel] promotes the reaction [BUB1B protein binds to CDC20 protein]; [Arsenic Trioxide co-treated with Paclitaxel] results in increased expression of BUB1B protein modified form; KNK 437 promotes the reaction [Arsenic Trioxide results in increased phosphorylation of BUB1B protein]
|
CTD |
PMID:19371599 PMID:19781537 |
|
NCBI chr 3:126,017,019...126,069,470
Ensembl chr 3:126,017,045...126,069,796
|
|
| G
|
Bzw1
|
basic leucine zipper and W2 domains 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of BZW1 mRNA
|
CTD |
PMID:22521957 |
|
NCBI chr 9:67,424,860...67,438,656
Ensembl chr 9:67,424,866...67,439,684
|
|
| G
|
Bzw2
|
basic leucine zipper and W2 domains 2
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of BZW2 mRNA
|
CTD |
PMID:27829220 |
|
NCBI chr 6:58,555,362...58,615,921
Ensembl chr 6:58,554,961...58,615,912
|
|
| G
|
C10h17orf78
|
similar to human chromosome 17 open reading frame 78
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of C17ORF78 mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr10:69,537,701...69,552,358
Ensembl chr10:69,535,160...69,583,661
|
|
| G
|
C10h5orf58
|
similar to human chromosome 5 open reading frame 58
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of C5ORF58 mRNA
|
CTD |
PMID:26705709 |
|
NCBI chr10:19,195,306...19,203,013
Ensembl chr10:19,193,035...19,205,380
|
|
| G
|
C1qb
|
complement C1q B chain
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of C1QB mRNA
|
CTD |
PMID:19128835 |
|
NCBI chr 5:154,402,276...154,407,827
Ensembl chr 5:154,402,279...154,407,840
|
|
| G
|
C1qtnf4
|
C1q and TNF related 4
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of C1QTNF4 mRNA
|
CTD |
PMID:26705709 |
|
NCBI chr 3:97,310,220...97,328,818
Ensembl chr 3:97,327,670...97,342,587
|
|
| G
|
C1qtnf7
|
C1q and TNF related 7
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of C1QTNF7 mRNA
|
CTD |
PMID:26705709 |
|
NCBI chr14:71,680,415...71,792,931
Ensembl chr14:71,680,479...71,792,865
|
|
| G
|
C1r
|
complement C1r
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of C1R mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 4:159,099,013...159,109,770
Ensembl chr 4:159,098,918...159,109,714
|
|
| G
|
C2cd3
|
C2 domain containing 3 centriole elongation regulator
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of C2CD3 mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr 1:164,127,304...164,225,088
Ensembl chr 1:164,127,281...164,225,086
|
|
| G
|
C2h3orf80
|
similar to human chromosome 3 open reading frame 80
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of C3ORF80 mRNA
|
CTD |
PMID:26705709 |
|
NCBI chr 2:155,435,287...155,438,099
Ensembl chr 2:155,434,073...155,437,507
|
|
| G
|
C3
|
complement C3
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of C3 mRNA
|
CTD |
PMID:29633893 |
|
NCBI chr 9:2,174,412...2,201,339
Ensembl chr 9:2,174,412...2,201,339
|
|
| G
|
C3h15orf48
|
similar to human chromosome 15 open reading frame 48
|
increases expression decreases expression
|
ISO
|
Arsenic Trioxide results in increased expression of NMES1 mRNA Arsenic Trioxide results in decreased expression of COXFA4L3 mRNA
|
CTD |
PMID:19128835 PMID:20458559 PMID:39716349 |
|
NCBI chr 3:130,173,535...130,177,088
Ensembl chr 3:130,173,416...130,177,089
|
|
| G
|
C4b
|
complement C4B
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of C4B mRNA
|
CTD |
PMID:29633893 |
|
NCBI chr20:4,201,979...4,216,292
Ensembl chr20:4,201,961...4,216,289
|
|
| G
|
C4bpa
|
complement component 4 binding protein, alpha
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of C4BPA mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr13:44,627,959...44,663,552
Ensembl chr13:44,627,982...44,663,471
|
|
| G
|
C5
|
complement C5
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of C5 mRNA
|
CTD |
PMID:27829220 PMID:29633893 |
|
NCBI chr 3:38,668,174...38,759,468
Ensembl chr 3:38,668,174...38,759,468
|
|
| G
|
C8h11orf54
|
similar to human chromosome 11 open reading frame 54
|
multiple interactions decreases expression
|
ISO
|
[Arsenic Trioxide co-treated with Ascorbic Acid] results in decreased expression of BKGD mRNA Arsenic Trioxide results in decreased expression of BKGD mRNA
|
CTD |
PMID:25555879 |
|
NCBI chr 8:20,405,240...20,427,811
Ensembl chr 8:20,405,241...20,427,811
|
|
| G
|
C8h11orf87
|
similar to human chromosome 11 open reading frame 87
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of C11ORF87 mRNA
|
CTD |
PMID:26705709 |
|
NCBI chr 8:61,958,626...61,966,119
Ensembl chr 8:61,957,676...61,968,365
|
|
| G
|
Ca3
|
carbonic anhydrase 3
|
multiple interactions decreases expression
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to CA3 protein] Arsenic Trioxide results in decreased expression of CAR3 mRNA
|
CTD |
PMID:26598702 PMID:35676786 |
|
NCBI chr 2:88,491,666...88,501,299
Ensembl chr 2:88,491,670...88,500,524
|
|
| G
|
Ca9
|
carbonic anhydrase 9
|
multiple interactions decreases expression
|
ISO
|
Arsenic Trioxide promotes the reaction [Silybin results in decreased expression of CA9 mRNA] Arsenic Trioxide results in decreased expression of CA9 mRNA
|
CTD |
PMID:21969006 |
|
NCBI chr 5:62,559,024...62,565,626
Ensembl chr 5:62,558,823...62,565,626
|
|
| G
|
Cab39l
|
calcium binding protein 39-like
|
increases expression decreases response to substance decreases expression multiple interactions
|
ISO
|
Arsenic Trioxide results in increased expression of CAB39L mRNA CAB39L protein alternative form results in decreased susceptibility to Arsenic Trioxide Arsenic Trioxide results in decreased expression of CAB39L protein alternative form CAB39L protein alternative form inhibits the reaction [Arsenic Trioxide results in decreased expression of CCNB1 protein]; CAB39L protein alternative form inhibits the reaction [Arsenic Trioxide results in decreased expression of CCND1 protein]; CAB39L protein alternative form inhibits the reaction [Arsenic Trioxide results in decreased expression of CTNNB1 mRNA]; CAB39L protein alternative form inhibits the reaction [Arsenic Trioxide results in decreased expression of CTNNB1 protein]; CAB39L protein alternative form inhibits the reaction [Arsenic Trioxide results in decreased expression of MYC protein]
|
CTD |
PMID:27829220 PMID:29059232 |
|
NCBI chr15:37,782,778...37,885,191
Ensembl chr15:37,782,870...37,919,742
|
|
| G
|
Cabin1
|
calcineurin binding protein 1
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of CABIN1 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr20:12,892,750...13,014,801
Ensembl chr20:12,892,771...13,014,800
|
|
| G
|
Cabp1
|
calcium binding protein 1
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of CABP1 mRNA
|
CTD |
PMID:35676786 |
|
NCBI chr12:47,045,914...47,109,614
Ensembl chr12:47,085,292...47,109,611
|
|
| G
|
Cacna1a
|
calcium voltage-gated channel subunit alpha1 A
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of CACNA1A mRNA
|
CTD |
PMID:24831965 |
|
NCBI chr19:40,425,560...40,724,810
Ensembl chr19:40,425,560...40,724,599
|
|
| G
|
Cacna1c
|
calcium voltage-gated channel subunit alpha1 C
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of CACNA1C mRNA
|
CTD |
PMID:24831965 |
|
NCBI chr 4:153,431,169...154,051,932
Ensembl chr 4:153,436,427...154,051,762
|
|
| G
|
Cacna1e
|
calcium voltage-gated channel subunit alpha1 E
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of CACNA1E mRNA
|
CTD |
PMID:27829220 |
|
NCBI chr13:69,125,048...69,613,795
Ensembl chr13:69,132,305...69,612,983
|
|
| G
|
Cacna2d1
|
calcium voltage-gated channel auxiliary subunit alpha2delta 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of CACNA2D1 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 4:19,902,324...20,330,287
Ensembl chr 4:19,905,764...20,330,147
|
|
| G
|
Cacna2d2
|
calcium voltage-gated channel auxiliary subunit alpha2delta 2
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of CACNA2D2 mRNA
|
CTD |
PMID:15761015 |
|
NCBI chr 8:116,950,860...117,082,159
Ensembl chr 8:116,950,907...117,081,759
|
|
| G
|
Cacnb2
|
calcium voltage-gated channel auxiliary subunit beta 2
|
increases expression decreases expression
|
ISO
|
Arsenic Trioxide results in increased expression of CACNB2 mRNA Arsenic Trioxide results in decreased expression of CACNB2 mRNA
|
CTD |
PMID:20458559 PMID:35676786 |
|
NCBI chr17:82,473,097...82,818,564
Ensembl chr17:82,473,129...82,818,564
|
|
| G
|
Cacng3
|
calcium voltage-gated channel auxiliary subunit gamma 3
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of CACNG3 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 1:186,632,334...186,728,220
Ensembl chr 1:186,632,323...186,728,214
|
|
| G
|
Cacng5
|
calcium voltage-gated channel auxiliary subunit gamma 5
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of CACNG5 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr10:93,327,142...93,369,244
Ensembl chr10:93,327,150...93,336,667
|
|
| G
|
Cad
|
carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of CAD mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 6:31,012,091...31,035,098
Ensembl chr 6:31,012,091...31,035,297
|
|
| G
|
Cadm1
|
cell adhesion molecule 1
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of CADM1 mRNA
|
CTD |
PMID:27829220 |
|
NCBI chr 8:56,744,374...57,075,264
Ensembl chr 8:56,744,372...57,080,192
|
|
| G
|
Calb2
|
calbindin 2
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to CALB2 protein]
|
CTD |
PMID:26598702 |
|
NCBI chr19:55,023,849...55,050,858
Ensembl chr19:55,023,838...55,057,952
|
|
| G
|
Cald1
|
caldesmon 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of CALD1 mRNA
|
CTD |
PMID:22535156 |
|
NCBI chr 4:64,232,906...64,414,085
Ensembl chr 4:64,233,171...64,414,085
|
|
| G
|
Calr
|
calreticulin
|
increases expression decreases expression multiple interactions increases localization
|
ISO
|
Arsenic Trioxide results in increased expression of CALR protein Arsenic Trioxide results in decreased expression of CALR mRNA Resveratrol inhibits the reaction [Arsenic Trioxide results in increased expression of CALR protein] Arsenic Trioxide results in increased localization of CALR protein
|
CTD |
PMID:20458559 PMID:25107562 PMID:38684648 |
|
NCBI chr19:40,213,367...40,218,262
Ensembl chr19:40,213,239...40,219,236
|
|
| G
|
Camk2a
|
calcium/calmodulin-dependent protein kinase II alpha
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of CAMK2A protein
|
CTD |
PMID:24831965 |
|
NCBI chr18:56,648,779...56,711,505
Ensembl chr18:56,649,025...56,711,504
|
|
| G
|
Camk2d
|
calcium/calmodulin-dependent protein kinase II delta
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of CAMK2D mRNA
|
CTD |
PMID:24831965 |
|
NCBI chr 2:217,698,324...217,961,898
Ensembl chr 2:217,698,551...217,960,276
|
|
| G
|
Camk2g
|
calcium/calmodulin-dependent protein kinase II gamma
|
increases expression multiple interactions
|
ISO
|
Arsenic Trioxide results in increased expression of CAMK2G mRNA [Arsenic Trioxide co-treated with antimony trichloride] results in increased expression of CAMK2G mRNA
|
CTD |
PMID:20458559 PMID:34091186 |
|
NCBI chr15:3,553,238...3,612,310
Ensembl chr15:3,553,294...3,612,310
|
|
| G
|
Camk4
|
calcium/calmodulin-dependent protein kinase IV
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of CAMK4 mRNA; Arsenic Trioxide results in decreased expression of CAMK4 protein
|
CTD |
PMID:19410645 PMID:24831965 PMID:26821021 |
|
NCBI chr18:24,857,152...25,076,054
Ensembl chr18:24,857,146...25,077,193
|
|
| G
|
Camp
|
cathelicidin antimicrobial peptide
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of CAMP mRNA
|
CTD |
PMID:19128835 |
|
NCBI chr 8:118,720,184...118,721,998
Ensembl chr 8:118,720,184...118,721,998
|
|
| G
|
Canx
|
calnexin
|
increases expression decreases expression multiple interactions
|
ISO
|
Arsenic Trioxide results in increased expression of CANX mRNA; Arsenic Trioxide results in increased expression of CANX protein Arsenic Trioxide results in decreased expression of CANX protein Resveratrol inhibits the reaction [Arsenic Trioxide results in increased expression of CANX protein]
|
CTD |
PMID:20458559 PMID:25107562 PMID:25419056 |
|
NCBI chr10:35,124,941...35,157,954
Ensembl chr10:35,124,941...35,157,857
|
|
| G
|
Capg
|
capping actin protein, gelsolin like
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of CAPG mRNA
|
CTD |
PMID:22521957 |
|
NCBI chr 4:106,152,912...106,170,010
Ensembl chr 4:106,152,890...106,170,672
|
|
| G
|
Capn1
|
calpain 1
|
increases cleavage increases expression multiple interactions
|
ISO EXP
|
Arsenic Trioxide results in increased cleavage of CAPN1 protein Arsenic Trioxide results in increased expression of CAPN1 mRNA; Arsenic Trioxide results in increased expression of CAPN1 protein 2-aminoethoxydiphenyl borate inhibits the reaction [Arsenic Trioxide results in increased expression of CAPN1 protein]; 2-aminoethyl diphenylborinate inhibits the reaction [Arsenic Trioxide results in increased expression of CAPN1 protein]; ATF4 protein promotes the reaction [Arsenic Trioxide results in increased expression of CAPN1 protein]; PD 150606 inhibits the reaction [Arsenic Trioxide results in increased expression of CAPN1 protein]; Quin2 inhibits the reaction [Arsenic Trioxide results in increased expression of CAPN1 protein] fexofenadine inhibits the reaction [Arsenic Trioxide results in increased expression of CAPN1 protein]; tanshinone inhibits the reaction [Arsenic Trioxide results in increased expression of CAPN1 protein]
|
CTD |
PMID:19695276 PMID:24641850 PMID:25258189 PMID:25419056 PMID:27461142 PMID:27638049 PMID:31274337 PMID:40041754 More...
|
|
NCBI chr 1:212,705,219...212,736,134
Ensembl chr 1:212,705,222...212,729,445
|
|
| G
|
Capn10
|
calpain 10
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of CAPN10 mRNA
|
CTD |
PMID:15761015 |
|
NCBI chr 9:100,943,665...100,957,910
Ensembl chr 9:100,945,551...100,957,912
|
|
| G
|
Capn2
|
calpain 2
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of CAPN2 mRNA; Arsenic Trioxide results in increased expression of CAPN2 protein
|
CTD |
PMID:19695276 PMID:36801614 |
|
NCBI chr13:96,681,902...96,732,625
Ensembl chr13:96,681,848...96,732,625
|
|
| G
|
Capn6
|
calpain 6
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of CAPN6 mRNA
|
CTD |
PMID:26705709 |
|
NCBI chr X:112,177,467...112,202,178
Ensembl chr X:112,177,467...112,202,178
|
|
| G
|
Capns1
|
calpain, small subunit 1
|
increases expression decreases response to substance
|
ISO
|
Arsenic Trioxide results in increased expression of CAPNS1 protein CAPNS1 protein results in decreased susceptibility to Arsenic Trioxide
|
CTD |
PMID:20707922 PMID:25419056 |
|
NCBI chr 1:94,572,083...94,582,332
Ensembl chr 1:94,572,083...94,583,368
|
|
| G
|
Capza2
|
capping actin protein of muscle Z-line subunit alpha 2
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of CAPZA2 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 4:46,944,040...46,979,930
Ensembl chr 4:46,895,701...46,979,938
|
|
| G
|
Capzb
|
capping actin protein of muscle Z-line subunit beta
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of CAPZB mRNA
|
CTD |
PMID:12852829 |
|
NCBI chr 5:156,718,619...156,818,623
Ensembl chr 5:156,650,432...156,818,619
|
|
| G
|
Car2
|
carbonic anhydrase 2
|
increases expression decreases expression
|
ISO
|
Arsenic Trioxide results in increased expression of CAR2 protein Arsenic Trioxide results in decreased expression of CA2 mRNA
|
CTD |
PMID:25419056 PMID:39716349 |
|
NCBI chr 2:88,462,883...88,478,012
Ensembl chr 2:88,462,872...88,478,064
|
|
| G
|
Card6
|
caspase recruitment domain family, member 6
|
multiple interactions
|
ISO
|
[sanguinarine co-treated with Arsenic Trioxide] results in increased expression of CARD6 mRNA
|
CTD |
PMID:24345465 |
|
NCBI chr 2:55,921,832...55,934,388
Ensembl chr 2:55,921,832...55,934,363
|
|
| G
|
Card9
|
caspase recruitment domain family, member 9
|
multiple interactions
|
ISO
|
[Arsenic Trioxide co-treated with Bortezomib] results in increased expression of CARD9 mRNA
|
CTD |
PMID:20471514 |
|
NCBI chr 3:29,569,907...29,578,402
Ensembl chr 3:29,569,959...29,578,402
|
|
| G
|
Carm1
|
coactivator-associated arginine methyltransferase 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of CARM1 protein
|
CTD |
PMID:25419056 |
|
NCBI chr 8:28,373,370...28,418,056
Ensembl chr 8:28,373,362...28,418,056
|
|
| G
|
Cars1
|
cysteinyl-tRNA synthetase 1
|
multiple interactions increases expression decreases expression
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to CARS1 protein] Arsenic Trioxide results in increased expression of CARS1 mRNA Arsenic Trioxide results in decreased expression of CARS1 mRNA
|
CTD |
PMID:12852829 PMID:24356939 PMID:26598702 |
|
NCBI chr 1:208,183,092...208,225,425
Ensembl chr 1:208,182,788...208,225,407
|
|
| G
|
Cask
|
calcium/calmodulin dependent serine protein kinase
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of CASK mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr X:11,572,328...11,915,831
Ensembl chr X:11,572,636...11,911,948
|
|
| G
|
Caskin2
|
cask-interacting protein 2
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of CASKIN2 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr10:101,526,131...101,540,362
Ensembl chr10:101,526,195...101,540,349
|
|
| G
|
Casp1
|
caspase 1
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increases expression multiple interactions increases activity increases cleavage decreases expression
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ISO EXP
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Arsenic Trioxide results in increased expression of CASP1 mRNA; Arsenic Trioxide results in increased expression of CASP1 protein modified form [Arsenic Trioxide co-treated with Lipopolysaccharides] results in increased cleavage of CASP1 protein; Febuxostat inhibits the reaction [Arsenic Trioxide results in increased expression of CASP1 protein]; Lenalidomide inhibits the reaction [[Arsenic Trioxide co-treated with Lipopolysaccharides] results in increased cleavage of CASP1 protein]; N-(1,2,3,5,6,7-hexahydro-S-indacen-4-ylcarbamoyl)-4-(2-hydroxy-2-propanyl)-2-furansulfonamide inhibits the reaction [[Arsenic Trioxide co-treated with Lipopolysaccharides] results in increased cleavage of CASP1 protein]; Taurine inhibits the reaction [[Arsenic Trioxide co-treated with Lipopolysaccharides] results in increased cleavage of CASP1 protein] Arsenic Trioxide results in increased activity of CASP1 protein Arsenic Trioxide results in increased cleavage of CASP1 protein 3-methyladenine inhibits the reaction [[Arsenic Trioxide co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased cleavage of CASP1 protein]; [sanguinarine co-treated with Arsenic Trioxide] results in increased expression of CASP1 mRNA; AS3MT mRNA promotes the reaction [Arsenic Trioxide results in increased expression of CASP1 protein modified form]; CA 074 methyl ester inhibits the reaction [[Arsenic Trioxide co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased cleavage of CASP1 protein]; IGF2BP2 protein promotes the reaction [Arsenic Trioxide results in increased expression of CASP1 protein modified form]; METTL14 protein promotes the reaction [Arsenic Trioxide results in increased expression of CASP1 protein modified form]; N-(1,2,3,5,6,7-hexahydro-S-indacen-4-ylcarbamoyl)-4-(2-hydroxy-2-propanyl)-2-furansulfonamide inhibits the reaction [[Arsenic Trioxide co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased cleavage of CASP1 protein]; Taurine inhibits the reaction [[Arsenic Trioxide co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased cleavage of CASP1 protein] Acetylcysteine inhibits the reaction [Arsenic Trioxide inhibits the reaction [anthrax toxin results in increased cleavage of CASP1 protein]]; Arsenic Trioxide inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased activity of CASP1 protein]; Arsenic Trioxide inhibits the reaction [anthrax toxin results in increased cleavage of CASP1 protein]; Arsenic Trioxide inhibits the reaction [Nigericin results in increased cleavage of CASP1 protein]; Arsenic Trioxide results in increased activity of and results in increased cleavage of CASP1 protein; Taurine inhibits the reaction [Arsenic Trioxide results in increased activity of and results in increased cleavage of CASP1 protein] Arsenic Trioxide results in decreased expression of CASP1 mRNA Arsenic Trioxide results in increased expression of CASP1 protein; Arsenic Trioxide results in increased expression of CASP1 protein modified form
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CTD |
PMID:9734658 PMID:9801394 PMID:15073043 PMID:23430110 PMID:24337744 PMID:24345465 PMID:30237538 PMID:30660605 PMID:35226250 PMID:37689273 More...
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NCBI chr 8:10,746,338...10,882,295
Ensembl chr 8:10,746,333...10,882,275
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| G
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Casp12
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caspase 12
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increases expression multiple interactions increases cleavage increases degradation
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EXP ISO
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Arsenic Trioxide results in increased expression of CASP12 mRNA; Arsenic Trioxide results in increased expression of CASP12 protein modified form 2-aminoethoxydiphenyl borate inhibits the reaction [Arsenic Trioxide results in increased cleavage of CASP12 protein]; 2-aminoethyl diphenylborinate inhibits the reaction [Arsenic Trioxide results in increased expression of CASP12 protein modified form]; 4-phenylbutyric acid inhibits the reaction [Arsenic Trioxide results in increased expression of CASP12 protein modified form]; ATF4 protein promotes the reaction [Arsenic Trioxide results in increased expression of CASP12 protein modified form]; DDIT3 mutant form inhibits the reaction [Arsenic Trioxide results in increased degradation of CASP12 protein]; HSPA5 mutant form inhibits the reaction [Arsenic Trioxide results in increased degradation of CASP12 protein]; PD 150606 inhibits the reaction [Arsenic Trioxide results in increased cleavage of CASP12 protein]; Quin2 inhibits the reaction [Arsenic Trioxide results in increased cleavage of CASP12 protein]; Thapsigargin promotes the reaction [Arsenic Trioxide results in increased expression of CASP12 protein modified form] Arsenic Trioxide promotes the reaction [tetraarsenic tetrasulfide results in increased cleavage of CASP12 protein]; Arsenic Trioxide results in increased expression of and results in increased activity of CASP12 protein; MT2A protein inhibits the reaction [Arsenic Trioxide results in increased expression of CASP12 protein modified form]; tetraarsenic tetrasulfide promotes the reaction [Arsenic Trioxide results in increased cleavage of CASP12 protein] Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased cleavage of CASP12 protein]
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CTD |
PMID:19695276 PMID:19730151 PMID:21145380 PMID:22959511 PMID:23664956 PMID:24157283 PMID:26110921 PMID:27461142 PMID:27638049 PMID:34091186 More...
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NCBI chr 8:10,927,188...10,954,442
Ensembl chr 8:10,926,994...10,954,442
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| G
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Casp2
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caspase 2
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decreases expression increases expression
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ISO
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Arsenic Trioxide results in decreased expression of CASP2 mRNA Arsenic Trioxide results in increased expression of CASP2; Arsenic Trioxide results in increased expression of CASP2 mRNA
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CTD |
PMID:9801394 PMID:15073043 PMID:17530438 |
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NCBI chr 4:72,116,265...72,134,023
Ensembl chr 4:72,116,246...72,134,022
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| G
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Casp3
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caspase 3
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increases activity increases cleavage increases expression increases degradation affects activity multiple interactions affects expression decreases expression
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ISO EXP
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Arsenic Trioxide analog results in increased activity of CASP3 protein; Arsenic Trioxide results in increased activity of CASP3 protein Arsenic Trioxide results in increased cleavage of CASP3 protein Arsenic Trioxide results in increased expression of CASP3; Arsenic Trioxide results in increased expression of CASP3 mRNA; Arsenic Trioxide results in increased expression of CASP3 protein; Arsenic Trioxide results in increased expression of CASP3 protein modified form Arsenic Trioxide results in increased degradation of CASP3 protein Arsenic Trioxide affects the activity of CASP3 protein 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt inhibits the reaction [Arsenic Trioxide results in increased activity of CASP3 protein]; 18alpha,20beta-hydroxy-11-oxo-norolean-12-en-3beta-yl-2-O-beta-D-glucopyranurosyl-alpha-D-glucopyranosiduronate magnesium tetrahydrate inhibits the reaction [Arsenic Trioxide results in increased expression of and results in increased cleavage of CASP3 protein]; 18alpha,20beta-hydroxy-11-oxo-norolean-12-en-3beta-yl-2-O-beta-D-glucopyranurosyl-alpha-D-glucopyranosiduronate magnesium tetrahydrate inhibits the reaction [Arsenic Trioxide results in increased expression of CASP3 protein]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Arsenic Trioxide results in increased activity of CASP3 protein]; 2-aminoethoxydiphenyl borate inhibits the reaction [Arsenic Trioxide results in increased cleavage of CASP3 protein]; 2-aminoethyl diphenylborinate inhibits the reaction [Arsenic Trioxide results in increased expression of CASP3 protein modified form]; 4-phenylbutyric acid inhibits the reaction [Arsenic Trioxide results in increased expression of CASP3 protein modified form]; [Genistein co-treated with Arsenic Trioxide] results in decreased expression of CASP3 protein; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased cleavage of and results in increased activity of CASP3 protein]; Arsenic Trioxide affects the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the cleavage of CASP3 protein]; Arsenic Trioxide affects the reaction [lipopolysaccharide, E coli O55-B5 affects the cleavage of CASP3 protein]; Arsenic Trioxide promotes the reaction [CDKN1A protein binds to CASP3 protein]; Arsenic Trioxide promotes the reaction [Drugs, Chinese Herbal results in decreased expression of CASP3 protein]; Arsenic Trioxide results in increased activity of and results in increased cleavage of CASP3 protein; Arsenic Trioxide results in increased cleavage of and results in increased activity of CASP3 protein; Arsenic Trioxide results in increased expression of and results in increased cleavage of CASP3 protein; aspartyl-glutamyl-valyl-aspartal inhibits the reaction [Arsenic Trioxide results in increased cleavage of and results in increased activity of CASP3 protein]; ATF4 protein affects the reaction [Arsenic Trioxide results in increased cleavage of CASP3 protein]; ATF4 protein promotes the reaction [Arsenic Trioxide results in increased expression of CASP3 protein modified form]; baicalin inhibits the reaction [Arsenic Trioxide results in increased expression of CASP3 mRNA]; baicalin inhibits the reaction [Arsenic Trioxide results in increased expression of CASP3 protein]; DDIT3 mutant form inhibits the reaction [Arsenic Trioxide results in increased activity of CASP3 protein]; Deoxyglucose promotes the reaction [Metformin inhibits the reaction [Arsenic Trioxide results in increased expression of CASP3 protein modified form]]; Glucose deficiency inhibits the reaction [Arsenic Trioxide results in increased expression of CASP3 protein modified form]; HSPA5 mutant form inhibits the reaction [Arsenic Trioxide results in increased activity of CASP3 protein]; Metformin inhibits the reaction [Arsenic Trioxide results in increased expression of CASP3 protein modified form]; PD 150606 inhibits the reaction [Arsenic Trioxide results in increased cleavage of CASP3 protein]; pyrazolanthrone inhibits the reaction [Arsenic Trioxide results in increased activity of CASP3 protein]; Quin2 inhibits the reaction [Arsenic Trioxide results in increased cleavage of CASP3 protein]; Resveratrol inhibits the reaction [Arsenic Trioxide results in increased activity of CASP3 protein]; Rotenone inhibits the reaction [Arsenic Trioxide results in increased expression of CASP3 protein modified form]; Thapsigargin promotes the reaction [Arsenic Trioxide results in increased expression of CASP3 protein modified form]; Thioctic Acid inhibits the reaction [Arsenic Trioxide results in increased activity of CASP3 protein]; Tretinoin promotes the reaction [Arsenic Trioxide results in increased activity of CASP3 protein] 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one promotes the reaction [Arsenic Trioxide results in increased cleavage of CASP3 protein]; 3,4-dihydro-5-(4-(1-piperidinyl)butoxy)-1(2H)-isoquinolinone inhibits the reaction [[Arsenic Trioxide co-treated with phytosphingosine] results in increased activity of CASP3 protein]; 3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [Arsenic Trioxide results in increased cleavage of CASP3 protein]; 4-amino-1,8-naphthalimide promotes the reaction [Arsenic Trioxide results in increased expression of CASP3 protein]; [Arsenic Trioxide co-treated with apatinib] results in increased cleavage of CASP3 protein; [Arsenic Trioxide co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] results in increased cleavage of CASP3 protein; [Arsenic Trioxide co-treated with BIBR 1532] results in increased activity of CASP3 protein; [Arsenic Trioxide co-treated with Bortezomib] results in increased activity of CASP3 protein; [Arsenic Trioxide co-treated with Bortezomib] results in increased cleavage of CASP3 protein; [Arsenic Trioxide co-treated with Curcumin] results in increased expression of CASP3 protein; [Arsenic Trioxide co-treated with Doxorubicin co-treated with Magnetite Nanoparticles analog] affects the expression of CASP3 mRNA; [Arsenic Trioxide co-treated with Doxorubicin co-treated with Magnetite Nanoparticles analog] affects the expression of CASP3 protein; [Arsenic Trioxide co-treated with epigallocatechin gallate] results in increased activity of CASP3 protein; [Arsenic Trioxide co-treated with Ethacrynic Acid] results in increased cleavage of CASP3 protein; [Arsenic Trioxide co-treated with IL24 protein] results in decreased expression of CASP3; [Arsenic Trioxide co-treated with Indomethacin] results in increased activity of CASP3 protein; [Arsenic Trioxide co-treated with lonidamine] results in increased cleavage of and results in increased activity of CASP3 protein; [Arsenic Trioxide co-treated with MIR15A protein co-treated with MIR16-1 protein] results in increased activity of CASP3 protein; [Arsenic Trioxide co-treated with phytosphingosine] results in increased activity of CASP3 protein; [Arsenic Trioxide co-treated with Plant Extracts] results in increased cleavage of CASP3 protein; [Arsenic Trioxide co-treated with TNFSF10 protein] results in increased cleavage of and results in increased activity of CASP3 protein; [Arsenic Trioxide results in decreased expression of MIR376A1 mRNA] which results in increased expression of CASP3 protein; [Arsenic Trioxide results in increased susceptibility to Ascorbic Acid] which results in increased cleavage of CASP3 protein; [aspartyl-glutamyl-valyl-aspartal results in decreased activity of CASP3 protein] inhibits the reaction [Arsenic Trioxide results in decreased phosphorylation of AKT1 protein]; [Bortezomib co-treated with Arsenic Trioxide] affects the expression of CASP3 protein; [Bortezomib co-treated with Arsenic Trioxide] results in increased activity of CASP3 protein; [Bortezomib co-treated with Arsenic Trioxide] results in increased expression of CASP3 protein; [CSF2 protein co-treated with Arsenic Trioxide] affects the activity of CASP3 protein; [CSF2 protein co-treated with Arsenic Trioxide] results in decreased expression of and results in increased cleavage of CASP3 protein; [Curcumin co-treated with Arsenic Trioxide] results in decreased expression of and results in increased cleavage of CASP3 protein; [Curcumin co-treated with Arsenic Trioxide] results in increased cleavage of CASP3 protein; [Dasatinib co-treated with Arsenic Trioxide] results in increased cleavage of CASP3 protein; [Docosahexaenoic Acids co-treated with Arsenic Trioxide] results in increased cleavage of CASP3 protein; [Genistein co-treated with Arsenic Trioxide] results in decreased expression of CASP3 protein; [MARVELD1 protein results in decreased susceptibility to Arsenic Trioxide] which results in decreased cleavage of CASP3 protein; [MCL1 mutant form results in increased susceptibility to [Ethacrynic Acid co-treated with Arsenic Trioxide]] which results in increased cleavage of CASP3 protein; [monomethylarsonous acid co-treated with dimethylarsinous acid co-treated with Arsenic Trioxide] results in increased activity of and results in increased cleavage of CASP3 protein; [sanguinarine co-treated with Arsenic Trioxide co-treated with TNFSF10 protein] results in increased cleavage of and results in increased activity of CASP3 protein; [sanguinarine co-treated with Arsenic Trioxide] results in increased activity of CASP3 protein; [sulforaphane co-treated with Arsenic Trioxide] results in increased cleavage of CASP3 protein; [Sulindac co-treated with Arsenic Trioxide] results in increased activity of CASP3 protein; [Vitamin K 2 co-treated with Arsenic Trioxide] results in increased expression of CASP3; [Zoledronic Acid co-treated with Arsenic Trioxide] results in increased cleavage of CASP3 protein; Acetylcysteine inhibits the reaction [[monomethylarsonous acid co-treated with dimethylarsinous acid co-treated with Arsenic Trioxide] results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [[sulforaphane co-treated with Arsenic Trioxide] results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [[Sulindac co-treated with Arsenic Trioxide] results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [[Vitamin K 2 co-treated with Arsenic Trioxide] results in increased expression of CASP3]; Acetylcysteine inhibits the reaction [Arsenic Trioxide promotes the reaction [Cisplatin results in increased cleavage of CASP3 protein]]; Acetylcysteine inhibits the reaction [Arsenic Trioxide promotes the reaction [Poly I-C results in increased activity of CASP3 protein]]; Acetylcysteine inhibits the reaction [Arsenic Trioxide promotes the reaction [Resveratrol results in increased expression of CASP3 protein]]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased expression of CASP3 protein]; Acetylcysteine inhibits the reaction [Cisplatin promotes the reaction [Arsenic Trioxide results in increased cleavage of CASP3 protein]]; Acetylcysteine inhibits the reaction [Poly I-C promotes the reaction [Arsenic Trioxide results in increased activity of CASP3 protein]]; Acetylcysteine inhibits the reaction [Resveratrol promotes the reaction [Arsenic Trioxide results in increased expression of CASP3 protein]]; Acetylcysteine inhibits the reaction [sulforaphane promotes the reaction [Arsenic Trioxide results in increased cleavage of CASP3 protein]]; AKT1 mutant form promotes the reaction [Arsenic Trioxide results in increased cleavage of CASP3 protein]; Aprepitant promotes the reaction [Arsenic Trioxide results in increased activity of CASP3 protein]; Arsenic Trioxide inhibits the reaction [Tunicamycin results in increased cleavage of CASP3 protein]; Arsenic Trioxide promotes the reaction [2-Methoxyestradiol results in increased expression of CASP3 protein modified form]; Arsenic Trioxide promotes the reaction [Aprepitant results in increased activity of CASP3 protein]; Arsenic Trioxide promotes the reaction [Cisplatin results in increased cleavage of CASP3 protein]; Arsenic Trioxide promotes the reaction [Curcumin results in increased expression of CASP3 protein modified form]; Arsenic Trioxide promotes the reaction [Dasatinib results in increased cleavage of CASP3 protein]; Arsenic Trioxide promotes the reaction [Deferoxamine results in increased expression of CASP3 mRNA]; Arsenic Trioxide promotes the reaction [Genistein results in increased activity of CASP3 protein]; Arsenic Trioxide promotes the reaction [Imatinib Mesylate results in increased activity of CASP3 protein]; Arsenic Trioxide promotes the reaction [Matrines results in increased cleavage of CASP3 protein]; Arsenic Trioxide promotes the reaction [Poly I-C results in increased activity of CASP3 protein]; Arsenic Trioxide promotes the reaction [puerarin results in increased expression of CASP3 protein]; Arsenic Trioxide promotes the reaction [Resveratrol results in increased expression of CASP3 protein]; Arsenic Trioxide promotes the reaction [Silybin results in increased activity of CASP3 protein]; Arsenic Trioxide promotes the reaction [Sorafenib results in decreased expression of CASP3 protein]; Arsenic Trioxide promotes the reaction [Sorafenib results in increased activity of CASP3 protein]; Arsenic Trioxide promotes the reaction [tetraarsenic tetrasulfide results in decreased expression of CASP3 mRNA]; Arsenic Trioxide promotes the reaction [tetraarsenic tetrasulfide results in increased cleavage of CASP3 protein]; Arsenic Trioxide promotes the reaction [VS-5584 results in increased cleavage of CASP3 protein]; Arsenic Trioxide results in decreased expression of and affects the cleavage of CASP3 protein; Arsenic Trioxide results in increased cleavage of and results in increased activity of CASP3 protein; Arsenic Trioxide results in increased expression of and results in increased activity of CASP3 protein; Arsenic Trioxide results in increased expression of and results in increased cleavage of CASP3 protein; Ascorbic Acid promotes the reaction [Arsenic Trioxide results in increased activity of CASP3 protein]; Ascorbic Acid promotes the reaction [Arsenic Trioxide results in increased cleavage of and results in increased activity of CASP3 protein]; BCL2 protein inhibits the reaction [Arsenic Trioxide results in increased activity of CASP3 protein]; BCL2L11 mutant form inhibits the reaction [Arsenic Trioxide results in increased cleavage of CASP3 protein]; benzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketone inhibits the reaction [Arsenic Trioxide results in increased activity of CASP3 protein]; benzyloxycarbonyl-valyl-alanyl-aspartic acid analog inhibits the reaction [[monomethylarsonous acid co-treated with dimethylarsinous acid co-treated with Arsenic Trioxide] results in increased cleavage of CASP3 protein]; benzyloxycarbonyl-valyl-alanyl-aspartic acid analog inhibits the reaction [Arsenic Trioxide results in increased cleavage of CASP3 protein]; buthionine analog promotes the reaction [Arsenic Trioxide results in increased activity of CASP3 protein]; Buthionine Sulfoximine promotes the reaction [Arsenic Trioxide results in increased activity of CASP3 protein]; CASP3 protein promotes the reaction [Arsenic Trioxide results in increased activity of IFNG protein]; Chloroquine promotes the reaction [Arsenic Trioxide results in increased cleavage of CASP3 protein]; Cisplatin promotes the reaction [Arsenic Trioxide results in increased cleavage of CASP3 protein]; Curcumin promotes the reaction [Arsenic Trioxide results in increased expression of CASP3 protein modified form]; Cycloheximide inhibits the reaction [Arsenic Trioxide results in increased cleavage of CASP3 protein]; Dactinomycin inhibits the reaction [Arsenic Trioxide results in increased cleavage of CASP3 protein]; DAPK2 protein affects the reaction [Arsenic Trioxide results in increased cleavage of CASP3 protein]; Dasatinib promotes the reaction [Arsenic Trioxide results in increased cleavage of CASP3 protein]; Dehydroascorbic Acid promotes the reaction [Arsenic Trioxide results in increased activity of CASP3 protein]; Deoxyglucose promotes the reaction [Arsenic Trioxide results in increased cleavage of and results in increased activity of CASP3 protein]; diphenyleneiodonium inhibits the reaction [Arsenic Trioxide results in increased activity of CASP3 protein]; Dithiothreitol inhibits the reaction [Arsenic Trioxide results in increased activity of CASP3 protein]; FAS protein affects the reaction [Arsenic Trioxide results in increased cleavage of CASP3 protein]; Genistein promotes the reaction [Arsenic Trioxide results in increased activity of CASP3 protein]; GRB10 protein promotes the reaction [[Arsenic Trioxide co-treated with apatinib] results in increased cleavage of CASP3 protein]; GSTP1 mutant form promotes the reaction [[Arsenic Trioxide co-treated with Ethacrynic Acid] results in increased cleavage of CASP3 protein]; HMOX1 protein inhibits the reaction [Arsenic Trioxide results in increased activity of CASP3 protein]; Hydrogen Peroxide inhibits the reaction [Arsenic Trioxide results in increased activity of CASP3 protein]; ID1 protein inhibits the reaction [Arsenic Trioxide results in increased expression of CASP3 protein]; Imatinib Mesylate promotes the reaction [Arsenic Trioxide results in increased activity of CASP3 protein]; KNK 437 promotes the reaction [Arsenic Trioxide results in increased cleavage of CASP3 protein]; MAPK8 mutant form inhibits the reaction [Arsenic Trioxide results in increased activity of CASP3 protein]; MAPK8 protein affects the reaction [Arsenic Trioxide results in increased activity of CASP3 protein]; MAPK9 mutant form inhibits the reaction [Arsenic Trioxide results in increased activity of CASP3 protein]; MARVELD1 protein inhibits the reaction [Arsenic Trioxide results in increased cleavage of CASP3 protein]; Matrines promotes the reaction [Arsenic Trioxide results in increased cleavage of CASP3 protein]; MIR203A protein promotes the reaction [Arsenic Trioxide results in increased activity of CASP3 protein]; MSI1 protein inhibits the reaction [Arsenic Trioxide results in increased activity of CASP3 protein]; MT2A protein inhibits the reaction [Arsenic Trioxide results in increased expression of CASP3 protein modified form]; NVP-BKM120 promotes the reaction [Arsenic Trioxide results in increased activity of CASP3 protein]; PMAIP1 protein promotes the reaction [[Bortezomib co-treated with Arsenic Trioxide] results in increased activity of CASP3 protein]; PMAIP1 protein promotes the reaction [Arsenic Trioxide results in increased activity of CASP3 protein]; Poly I-C promotes the reaction [Arsenic Trioxide results in increased activity of CASP3 protein]; pyrazolanthrone inhibits the reaction [[Arsenic Trioxide co-treated with Ethacrynic Acid] results in increased cleavage of CASP3 protein]; pyrazolanthrone inhibits the reaction [[Sulindac co-treated with Arsenic Trioxide] results in increased activity of CASP3 protein]; RARA gene mutant form inhibits the reaction [Tretinoin promotes the reaction [Arsenic Trioxide results in increased activity of CASP3 protein]]; Resveratrol promotes the reaction [Arsenic Trioxide results in increased expression of CASP3 protein]; SB 203580 inhibits the reaction [[Arsenic Trioxide co-treated with phytosphingosine] results in increased activity of CASP3 protein]; SB 203580 inhibits the reaction [Arsenic Trioxide results in increased cleavage of CASP3 protein]; Silybin promotes the reaction [Arsenic Trioxide results in increased expression of CASP3 mRNA]; Sorafenib promotes the reaction [Arsenic Trioxide results in decreased expression of CASP3 protein]; Sorafenib promotes the reaction [Arsenic Trioxide results in increased activity of CASP3 protein]; sulforaphane promotes the reaction [Arsenic Trioxide results in increased cleavage of CASP3 protein]; tetraarsenic tetrasulfide promotes the reaction [Arsenic Trioxide results in decreased expression of CASP3 mRNA]; tetraarsenic tetrasulfide promotes the reaction [Arsenic Trioxide results in increased cleavage of CASP3 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [Arsenic Trioxide results in increased activity of CASP3 protein]; Tetradecanoylphorbol Acetate promotes the reaction [Arsenic Trioxide results in increased activity of CASP3 protein]; TNF protein promotes the reaction [Arsenic Trioxide results in increased activity of CASP3 protein]; TP53 protein inhibits the reaction [Arsenic Trioxide results in increased cleavage of and results in increased activity of CASP3 protein]; TP73 protein affects the reaction [Arsenic Trioxide results in increased cleavage of CASP3 protein]; Tretinoin promotes the reaction [Arsenic Trioxide results in increased activity of CASP3 protein]; venetoclax inhibits the reaction [Arsenic Trioxide results in increased cleavage of CASP3 protein]; Wortmannin inhibits the reaction [Hydrogen Peroxide inhibits the reaction [Arsenic Trioxide results in increased activity of CASP3 protein]]; zinc protoporphyrin promotes the reaction [Arsenic Trioxide results in increased activity of CASP3 protein] Arsenic Trioxide affects the expression of CASP3 protein Arsenic Trioxide results in decreased expression of CASP3 mRNA; Arsenic Trioxide results in decreased expression of CASP3 protein 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Arsenic Trioxide results in increased expression of CASP3 protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [salvianolic acid B inhibits the reaction [Arsenic Trioxide results in increased activity of CASP3 protein]]; [17-(dimethylaminoethylamino)-17-demethoxygeldanamycin co-treated with Arsenic Trioxide] results in increased activity of CASP3 protein; [Buthionine Sulfoximine co-treated with Arsenic Trioxide] results in increased activity of CASP3 protein; [Ditiocarb co-treated with Arsenic Trioxide] results in increased activity of CASP3 protein; [VER 155008 co-treated with Arsenic Trioxide] results in increased activity of CASP3 protein; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased cleavage of CASP3 protein]; Ascorbic Acid inhibits the reaction [Arsenic Trioxide results in increased activity of CASP3 protein]; benzyloxycarbonyl-valyl-alanyl-aspartic acid analog inhibits the reaction [Arsenic Trioxide results in increased activity of CASP3 protein]; crocin inhibits the reaction [Arsenic Trioxide results in increased expression of CASP3 mRNA]; crocin inhibits the reaction [Arsenic Trioxide results in increased expression of CASP3 protein]; ferrostatin-1 inhibits the reaction [Arsenic Trioxide results in increased cleavage of CASP3 protein]; Genistein inhibits the reaction [Arsenic Trioxide results in increased activity of CASP3 protein]; GSR protein inhibits the reaction [Arsenic Trioxide results in increased cleavage of CASP3 protein]; HTS 466284 inhibits the reaction [Arsenic Trioxide results in increased activity of CASP3 protein]; pyrazolanthrone inhibits the reaction [Arsenic Trioxide results in increased expression of CASP3 protein]; salvianolic acid A inhibits the reaction [Arsenic Trioxide results in increased expression of CASP3 protein]; salvianolic acid B inhibits the reaction [Arsenic Trioxide results in increased activity of CASP3 protein]; SB 203580 inhibits the reaction [Arsenic Trioxide results in increased expression of CASP3 protein]; trans-sodium crocetinate inhibits the reaction [Arsenic Trioxide results in increased expression of CASP3 protein]
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CTD |
PMID:9734658 PMID:9801394 PMID:10428472 PMID:10477740 PMID:10673743 PMID:10850458 PMID:11027660 PMID:11146441 PMID:11304686 PMID:11739184 PMID:11779429 PMID:11940349 PMID:12005185 PMID:12063550 PMID:12135670 PMID:12148893 PMID:12168106 PMID:12181429 PMID:12296996 PMID:12480548 PMID:12609832 PMID:12684647 PMID:12750841 PMID:12754411 PMID:12851490 PMID:12883035 PMID:12883267 PMID:12931215 PMID:12962562 PMID:14610070 PMID:14632209 PMID:14668793 PMID:15131059 PMID:15142122 PMID:15314284 PMID:15493360 PMID:15637062 PMID:15665116 PMID:15688020 PMID:15761769 PMID:15774171 PMID:15979664 PMID:15979894 PMID:16174796 PMID:16360329 PMID:16569477 PMID:16867262 PMID:16951922 PMID:17237268 PMID:17374990 PMID:17495969 PMID:17673311 PMID:17869043 PMID:17956674 PMID:18281123 PMID:18332854 PMID:18451318 PMID:18491231 PMID:18539383 PMID:18546268 PMID:18566239 PMID:18599993 PMID:18718063 PMID:19014326 PMID:19208092 PMID:19364129 PMID:19408305 PMID:19662097 PMID:19695276 PMID:19763917 PMID:19771260 PMID:20016248 PMID:20079407 PMID:20138156 PMID:20164150 PMID:20200477 PMID:20219070 PMID:20356860 PMID:20408844 PMID:20416161 PMID:20458559 PMID:20471514 PMID:20534739 PMID:20605902 PMID:20632473 PMID:20693187 PMID:20723298 PMID:20724260 PMID:20799280 PMID:20889596 PMID:20937774 PMID:20950636 PMID:20953137 PMID:20977926 PMID:21056550 PMID:21061466 PMID:21078540 PMID:21145380 PMID:21418039 PMID:21518486 PMID:21533816 PMID:21565247 PMID:21594580 PMID:21649584 PMID:21655183 PMID:21889928 PMID:21969006 PMID:22072212 PMID:22199276 PMID:22753750 PMID:22922937 PMID:22959511 PMID:22977528 PMID:22988968 PMID:23041229 PMID:23082001 PMID:23201927 PMID:23293885 PMID:23337567 PMID:23363563 PMID:23373993 PMID:23542815 PMID:23664956 PMID:23700110 PMID:23721794 PMID:23737871 PMID:23832679 PMID:23861973 PMID:23892647 PMID:23967052 PMID:23980369 PMID:24157283 PMID:24273890 PMID:24312908 PMID:24345465 PMID:24377552 PMID:24466103 PMID:24634002 PMID:24685274 PMID:24738333 PMID:24801902 PMID:24944602 PMID:25003661 PMID:25174355 PMID:25258189 PMID:25335113 PMID:25416439 PMID:25449439 PMID:25499136 PMID:25574600 PMID:25787108 PMID:26110921 PMID:26160715 PMID:26772155 PMID:27430728 PMID:27461142 PMID:27592447 PMID:27638049 PMID:27770503 PMID:28391263 PMID:28587418 PMID:28978663 PMID:29095437 PMID:29164574 PMID:29266867 PMID:29486283 PMID:29574283 PMID:29767511 PMID:29774349 PMID:29944906 PMID:30091188 PMID:30145367 PMID:30316766 PMID:30333888 PMID:30338810 PMID:30472098 PMID:31079498 PMID:31205918 PMID:31258454 PMID:31734849 PMID:32017938 PMID:32305283 PMID:32919218 PMID:32920515 PMID:33462182 PMID:33603344 PMID:33846815 PMID:34091186 PMID:34303041 PMID:34333357 PMID:34560123 PMID:34675983 PMID:34953944 PMID:35088608 PMID:35195477 PMID:35317438 PMID:36509116 PMID:36801614 PMID:38160894 PMID:38237221 PMID:38784214 PMID:39223679 More...
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NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732
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| G
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Casp4
|
caspase 4
|
increases expression multiple interactions increases cleavage increases activity
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EXP ISO
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Arsenic Trioxide results in increased expression of CASP4 mRNA [sanguinarine co-treated with Arsenic Trioxide] results in increased expression of CASP4 mRNA; [sulforaphane co-treated with Arsenic Trioxide] results in increased cleavage of CASP4 protein; Acetylcysteine inhibits the reaction [[sulforaphane co-treated with Arsenic Trioxide] results in increased cleavage of CASP4 protein]; Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to CASP4 protein]; isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone inhibits the reaction [Arsenic Trioxide results in increased activity of CASP4 protein] Arsenic Trioxide results in increased cleavage of CASP4 protein
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CTD |
PMID:11940349 PMID:19730151 PMID:20138156 PMID:22922937 PMID:24345465 PMID:25258189 PMID:26598702 More...
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|
NCBI chr 8:10,883,817...10,919,978
Ensembl chr 8:10,883,769...10,920,727
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| G
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Casp6
|
caspase 6
|
increases expression increases activity multiple interactions
|
ISO
|
Arsenic Trioxide results in increased expression of CASP6 mRNA Arsenic Trioxide results in increased activity of CASP6 protein Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased activity of CASP6 protein]
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CTD |
PMID:11940349 PMID:24157283 |
|
NCBI chr 2:221,140,287...221,152,727
Ensembl chr 2:221,140,256...221,152,726
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| G
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Casp7
|
caspase 7
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multiple interactions increases activity increases cleavage
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ISO EXP
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[Arsenic Trioxide co-treated with apatinib] results in increased cleavage of CASP7 protein; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased activity of CASP7 protein]; Arsenic Trioxide promotes the reaction [2-Methoxyestradiol results in increased expression of CASP7 protein modified form] Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased activity of CASP7 protein]; benzyloxycarbonyl-valyl-alanyl-aspartic acid analog inhibits the reaction [Arsenic Trioxide results in increased activity of CASP7 protein] Arsenic Trioxide results in increased cleavage of CASP7 protein 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Arsenic Trioxide results in increased activity of CASP7 protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased activity of CASP7 protein]; Arsenic Trioxide results in increased cleavage of and results in increased activity of CASP7 protein; DDIT3 mutant form inhibits the reaction [Arsenic Trioxide results in increased activity of CASP7 protein]; HSPA5 mutant form inhibits the reaction [Arsenic Trioxide results in increased activity of CASP7 protein]; pyrazolanthrone inhibits the reaction [Arsenic Trioxide results in increased activity of CASP7 protein]; Tretinoin promotes the reaction [Arsenic Trioxide results in increased cleavage of CASP7 protein]
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CTD |
PMID:12181429 PMID:12480548 PMID:12883267 PMID:15493360 PMID:15688020 PMID:16360329 PMID:19695276 PMID:19771260 PMID:20408844 PMID:20937774 PMID:21145380 PMID:22199276 PMID:23967052 PMID:24157283 PMID:39223679 More...
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|
NCBI chr 1:265,442,647...265,481,938
Ensembl chr 1:265,442,676...265,482,512
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|
| G
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Casp8
|
caspase 8
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increases activity increases cleavage multiple interactions increases expression affects activity
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ISO
|
Arsenic Trioxide results in increased activity of CASP8 protein Arsenic Trioxide results in increased cleavage of CASP8 protein [Arsenic Trioxide co-treated with Bortezomib] results in decreased expression of CASP8 mRNA; [Arsenic Trioxide co-treated with Curcumin] results in increased expression of CASP8 protein; [Arsenic Trioxide co-treated with Ethacrynic Acid] results in increased cleavage of CASP8 protein; [Arsenic Trioxide co-treated with lonidamine] results in increased cleavage of and results in increased activity of CASP8 protein; [Arsenic Trioxide co-treated with Quercetin] results in increased cleavage of and results in increased activity of CASP8 protein; [Arsenic Trioxide co-treated with TNF protein] results in increased cleavage of and results in increased activity of CASP8 protein; [Arsenic Trioxide co-treated with TNFSF10 protein] results in increased activity of CASP8 protein; [Bortezomib co-treated with Arsenic Trioxide] results in increased expression of CASP8 protein; [Buthionine Sulfoximine co-treated with Arsenic Trioxide] results in increased cleavage of CASP8 protein; [CSF2 protein co-treated with Arsenic Trioxide] results in decreased expression of and affects the activity of CASP8 protein; [sanguinarine co-treated with Arsenic Trioxide co-treated with TNFSF10 protein] results in increased cleavage of and results in increased activity of CASP8 protein; [sanguinarine co-treated with Arsenic Trioxide] results in increased activity of CASP8 protein; [Valproic Acid co-treated with Arsenic Trioxide] results in increased expression of CASP8 mRNA; [Valproic Acid co-treated with Arsenic Trioxide] results in increased expression of CASP8 protein; Arsenic Trioxide promotes the reaction [Poly I-C results in increased activity of CASP8 protein]; Arsenic Trioxide promotes the reaction [puerarin results in increased expression of CASP8 protein]; Arsenic Trioxide promotes the reaction [TNFSF10 protein results in increased cleavage of and results in increased activity of CASP8 protein]; Arsenic Trioxide results in increased cleavage of and results in increased activity of CASP8 protein; BCL2 inhibits the reaction [[Arsenic Trioxide co-treated with TNF protein] results in increased activity of CASP8 protein]; BCL2 protein inhibits the reaction [[Arsenic Trioxide co-treated with lonidamine] results in increased cleavage of and results in increased activity of CASP8 protein]; BCL2 protein inhibits the reaction [[Arsenic Trioxide co-treated with Quercetin] results in increased cleavage of and results in increased activity of CASP8 protein]; benzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone inhibits the reaction [[Arsenic Trioxide co-treated with TNF protein] results in increased cleavage of and results in increased activity of CASP8 protein]; Bortezomib promotes the reaction [Arsenic Trioxide results in increased activity of CASP8 protein]; FAS protein affects the reaction [Arsenic Trioxide results in increased cleavage of CASP8 protein]; Genistein promotes the reaction [Arsenic Trioxide results in increased cleavage of and results in increased activity of CASP8 protein]; isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone inhibits the reaction [Arsenic Trioxide promotes the reaction [TNFSF10 protein results in increased cleavage of and results in increased activity of CASP8 protein]]; MAPK8 protein affects the reaction [Arsenic Trioxide results in increased activity of CASP8 protein]; Poly I-C promotes the reaction [Arsenic Trioxide results in increased activity of CASP8 protein]; pyrazolanthrone inhibits the reaction [[Buthionine Sulfoximine co-treated with Arsenic Trioxide] results in increased cleavage of CASP8 protein]; pyrazolanthrone promotes the reaction [Arsenic Trioxide results in increased activity of CASP8 protein]; U 0126 promotes the reaction [Arsenic Trioxide results in increased activity of CASP8 protein] Arsenic Trioxide results in increased expression of CASP8 mRNA; Arsenic Trioxide results in increased expression of CASP8 protein; Arsenic Trioxide results in increased expression of CASP8 protein modified form Arsenic Trioxide promotes the reaction [Drugs, Chinese Herbal results in increased cleavage of CASP8 protein] Arsenic Trioxide affects the activity of CASP8 protein
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CTD |
PMID:10721769 PMID:12148893 PMID:12684647 PMID:12975549 PMID:16010437 PMID:16174796 PMID:16434995 PMID:16972261 PMID:17145888 PMID:17673311 PMID:18359480 PMID:18491231 PMID:18539383 PMID:18546268 PMID:19408305 PMID:20138156 PMID:20416161 PMID:20471514 PMID:20534739 PMID:20889596 PMID:20953137 PMID:21418039 PMID:21565247 PMID:21889928 PMID:23082001 PMID:24345465 PMID:24377552 PMID:25410152 PMID:25815518 PMID:27430728 PMID:28587418 PMID:29633893 PMID:34953944 PMID:36442592 PMID:38275666 More...
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|
NCBI chr 9:67,747,109...67,806,699
Ensembl chr 9:67,758,033...67,806,699
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|
| G
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Casp8ap2
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caspase 8 associated protein 2
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increases expression multiple interactions
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EXP ISO
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Arsenic Trioxide results in increased expression of CASP8AP2 mRNA Arsenic Trioxide results in increased localization of [CASP8AP2 protein co-treated with PML protein]; Arsenic Trioxide results in increased localization of and results in increased degradation of CASP8AP2 protein
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CTD |
PMID:19730151 PMID:23673342 |
|
NCBI chr 5:51,809,366...51,848,633
Ensembl chr 5:51,810,972...51,848,632
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| G
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Casp9
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caspase 9
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increases cleavage multiple interactions increases expression decreases expression increases activity
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ISO EXP
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Arsenic Trioxide results in increased cleavage of CASP9 protein Acetylcysteine inhibits the reaction [Arsenic Trioxide promotes the reaction [CASP9 protein binds to CYCS protein]]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased activity of CASP9 protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased cleavage of CASP9 protein]; Arsenic Trioxide promotes the reaction [CYCS protein binds to CASP9 protein] Arsenic Trioxide results in increased expression of CASP9 protein modified form Arsenic Trioxide results in decreased expression of CASP9 protein 17-(dimethylaminoethylamino)-17-demethoxygeldanamycin promotes the reaction [Arsenic Trioxide results in increased cleavage of CASP9 protein]; 3,4-dihydro-5-(4-(1-piperidinyl)butoxy)-1(2H)-isoquinolinone inhibits the reaction [[Arsenic Trioxide co-treated with phytosphingosine] results in increased activity of CASP9 protein]; [Arsenic Trioxide co-treated with phytosphingosine] results in increased activity of CASP9 protein; [Arsenic Trioxide co-treated with Plant Extracts] results in increased cleavage of CASP9 protein; [Bortezomib co-treated with Arsenic Trioxide] results in increased activity of CASP9 protein; [Bortezomib co-treated with Arsenic Trioxide] results in increased expression of CASP9 protein; [Curcumin co-treated with Arsenic Trioxide] results in increased cleavage of CASP9 protein; [Dasatinib co-treated with Arsenic Trioxide] results in increased cleavage of CASP9 protein; [Sulindac co-treated with Arsenic Trioxide] results in increased activity of CASP9 protein; [Valproic Acid co-treated with Arsenic Trioxide] results in increased expression of CASP9 mRNA; [Valproic Acid co-treated with Arsenic Trioxide] results in increased expression of CASP9 protein; Acetylcysteine inhibits the reaction [Arsenic Trioxide promotes the reaction [Poly I-C results in increased activity of CASP9 protein]]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased activity of CASP9 protein]; Acetylcysteine inhibits the reaction [Poly I-C promotes the reaction [Arsenic Trioxide results in increased activity of CASP9 protein]]; AKT1 mutant form promotes the reaction [Arsenic Trioxide results in increased cleavage of CASP9 protein]; ARL6IP5 protein promotes the reaction [Arsenic Trioxide results in increased cleavage of CASP9 protein]; Arsenic Trioxide analog results in increased cleavage of and results in increased activity of CASP9 protein; Arsenic Trioxide promotes the reaction [Dasatinib results in increased cleavage of CASP9 protein]; Arsenic Trioxide promotes the reaction [Ethacrynic Acid results in increased cleavage of CASP9 protein]; Arsenic Trioxide promotes the reaction [lonidamine results in increased cleavage of and results in increased activity of CASP9 protein]; Arsenic Trioxide promotes the reaction [Poly I-C results in increased activity of CASP9 protein]; Arsenic Trioxide promotes the reaction [Sorafenib results in increased activity of CASP9 protein]; Arsenic Trioxide results in increased cleavage of and results in increased activity of CASP9 protein; Arsenic Trioxide results in increased expression of and results in increased cleavage of CASP9 protein; BCL2 protein inhibits the reaction [Arsenic Trioxide promotes the reaction [lonidamine results in increased cleavage of and results in increased activity of CASP9 protein]]; BCL2 protein inhibits the reaction [lonidamine promotes the reaction [Arsenic Trioxide results in increased cleavage of and results in increased activity of CASP9 protein]]; BCL2L11 mutant form inhibits the reaction [Arsenic Trioxide results in increased cleavage of CASP9 protein]; Bortezomib promotes the reaction [Arsenic Trioxide results in increased activity of CASP9 protein]; Dasatinib promotes the reaction [Arsenic Trioxide results in increased cleavage of CASP9 protein]; Deoxyglucose promotes the reaction [Arsenic Trioxide results in increased cleavage of and results in increased activity of CASP9 protein]; Fluorouracil promotes the reaction [Arsenic Trioxide results in decreased expression of CASP9 protein]; Genistein promotes the reaction [Arsenic Trioxide results in increased activity of CASP9 protein]; GRB10 protein promotes the reaction [[Arsenic Trioxide co-treated with apatinib] results in increased cleavage of CASP9 protein]; GSTP1 mutant form promotes the reaction [[Arsenic Trioxide co-treated with Ethacrynic Acid] results in increased cleavage of CASP9 protein]; HSF1 protein affects the reaction [Arsenic Trioxide results in increased activity of CASP9 protein]; KNK 437 promotes the reaction [Arsenic Trioxide results in increased cleavage of CASP9 protein]; lonidamine promotes the reaction [Arsenic Trioxide results in increased cleavage of and results in increased activity of CASP9 protein]; MAPK8 protein affects the reaction [Arsenic Trioxide results in increased activity of CASP9 protein]; MCL1 mutant form promotes the reaction [[Arsenic Trioxide co-treated with Ethacrynic Acid] results in increased cleavage of CASP9 protein]; MIR203A protein promotes the reaction [Arsenic Trioxide results in increased activity of CASP9 protein]; Poly I-C promotes the reaction [Arsenic Trioxide results in increased activity of CASP9 protein]; salvin promotes the reaction [Arsenic Trioxide results in increased activity of CASP9 protein]; SB 203580 inhibits the reaction [[Arsenic Trioxide co-treated with phytosphingosine] results in increased activity of CASP9 protein]; Sorafenib promotes the reaction [Arsenic Trioxide results in increased activity of CASP9 protein]; STMN1 inhibits the reaction [Arsenic Trioxide results in increased cleavage of CASP9 protein]; TNF protein promotes the reaction [Arsenic Trioxide results in increased activity of CASP9 protein] Acetylcysteine inhibits the reaction [Arsenic Trioxide results in decreased expression of CASP9 protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased activity of CASP9 protein]; Arsenic Trioxide affects the reaction [lipopolysaccharide, E coli O55-B5 affects the cleavage of CASP9 protein]; Arsenic Trioxide promotes the reaction [Drugs, Chinese Herbal results in increased expression of CASP9 protein modified form]; Arsenic Trioxide results in increased cleavage of and results in increased activity of CASP9 protein; Drugs, Chinese Herbal promotes the reaction [Arsenic Trioxide results in increased expression of CASP9 protein modified form] Arsenic Trioxide results in increased expression of CASP9 mRNA
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CTD |
PMID:12148893 PMID:12480548 PMID:12492118 PMID:12883267 PMID:12975549 PMID:15493360 PMID:15688020 PMID:16010437 PMID:16646077 PMID:17237268 PMID:17374990 PMID:17673311 PMID:18281123 PMID:18336854 PMID:18387645 PMID:18491231 PMID:19371599 PMID:19408305 PMID:19468689 PMID:19695276 PMID:19730151 PMID:19771260 PMID:20138156 PMID:20219070 PMID:20408844 PMID:20471514 PMID:20534739 PMID:20605902 PMID:20657188 PMID:20723298 PMID:20953137 PMID:21061466 PMID:21145380 PMID:21418039 PMID:21518486 PMID:21565247 PMID:21655183 PMID:21889928 PMID:22496356 PMID:22753750 PMID:22963400 PMID:23041229 PMID:23082001 PMID:23239002 PMID:23737871 PMID:23980369 PMID:24157283 PMID:24377552 PMID:24634002 PMID:24801902 PMID:25174355 PMID:25258189 PMID:25416439 PMID:25815518 PMID:26160715 PMID:28587418 PMID:29164574 PMID:29266867 PMID:30472098 PMID:32305283 PMID:33462182 PMID:38275666 PMID:39223679 More...
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Ensembl chr 5:159,391,188...159,409,648
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| G
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Cat
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catalase
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increases response to substance multiple interactions decreases expression decreases response to substance decreases activity increases activity
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ISO EXP
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CAT results in increased susceptibility to Arsenic Trioxide [Arsenic Trioxide results in increased abundance of Arsenic] which results in decreased activity of CAT protein; [Arsenic Trioxide results in increased abundance of Arsenic] which results in increased activity of CAT protein; [boric acid co-treated with Arsenic Trioxide] affects the activity of CAT protein; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in decreased expression of CAT mRNA]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in decreased expression of CAT protein]; Apigenin inhibits the reaction [[Arsenic Trioxide results in increased abundance of Arsenic] which results in decreased activity of CAT protein]; Apigenin inhibits the reaction [[Arsenic Trioxide results in increased abundance of Arsenic] which results in increased activity of CAT protein]; crocin inhibits the reaction [Arsenic Trioxide results in decreased activity of CAT protein]; eriodictyol inhibits the reaction [Arsenic Trioxide results in decreased activity of CAT protein]; Folic Acid inhibits the reaction [Arsenic Trioxide results in decreased activity of CAT protein]; Linseed Oil inhibits the reaction [Arsenic Trioxide results in decreased activity of CAT protein]; naringenin inhibits the reaction [Arsenic Trioxide results in decreased activity of CAT protein]; oxymatrine inhibits the reaction [Arsenic Trioxide results in decreased activity of CAT protein]; polydatin inhibits the reaction [Arsenic Trioxide results in decreased activity of CAT protein]; Resveratrol inhibits the reaction [Arsenic Trioxide results in decreased activity of CAT protein]; Riboflavin inhibits the reaction [Arsenic Trioxide results in decreased activity of CAT protein]; salvianolic acid A inhibits the reaction [Arsenic Trioxide results in decreased activity of CAT protein]; trans-sodium crocetinate inhibits the reaction [Arsenic Trioxide results in decreased activity of CAT protein]; trans-sodium crocetinate inhibits the reaction [Arsenic Trioxide results in decreased expression of CAT protein]; Vitamin B 12 promotes the reaction [Folic Acid inhibits the reaction [Arsenic Trioxide results in decreased activity of CAT protein]] 18alpha,20beta-hydroxy-11-oxo-norolean-12-en-3beta-yl-2-O-beta-D-glucopyranurosyl-alpha-D-glucopyranosiduronate magnesium tetrahydrate inhibits the reaction [Arsenic Trioxide results in decreased activity of CAT protein]; Arsenic Trioxide affects the reaction [1,2-Dimethylhydrazine results in decreased activity of CAT protein]; Ascorbic Acid inhibits the reaction [Arsenic Trioxide results in decreased activity of CAT protein]; baicalin inhibits the reaction [Arsenic Trioxide results in decreased activity of CAT protein]; beta Carotene inhibits the reaction [Arsenic Trioxide results in decreased activity of CAT protein]; CAT protein inhibits the reaction [Arsenic Trioxide results in decreased activity of TERT protein]; CAT protein inhibits the reaction [Arsenic Trioxide results in increased expression of HMOX1 protein]; Melatonin inhibits the reaction [Arsenic Trioxide results in decreased expression of CAT protein]; Resveratrol inhibits the reaction [Arsenic Trioxide results in decreased activity of CAT protein] Arsenic Trioxide results in decreased expression of CAT mRNA; Arsenic Trioxide results in decreased expression of CAT protein CAT protein results in decreased susceptibility to Arsenic Trioxide [Cisplatin co-treated with Arsenic Trioxide] results in decreased activity of CAT protein; [Fluorouracil co-treated with Arsenic Trioxide] results in decreased activity of CAT protein; [ruxolitinib co-treated with Arsenic Trioxide] results in decreased expression of CAT mRNA; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in decreased expression of CAT protein]; CAT mutant form promotes the reaction [Arsenic Trioxide promotes the reaction [Ethacrynic Acid results in decreased expression of MCL1 protein]]; CAT protein inhibits the reaction [[Arsenic Trioxide results in increased abundance of Hydrogen Peroxide] which results in increased expression of ARL6IP5 protein]; CAT protein inhibits the reaction [Arsenic Trioxide results in increased expression of PTGS2 mRNA]; CAT protein results in decreased susceptibility to [Arsenic Trioxide co-treated with Ascorbic Acid]; Docosahexaenoic Acids inhibits the reaction [Arsenic Trioxide results in decreased activity of CAT protein]; Grape Seed Proanthocyanidins inhibits the reaction [Arsenic Trioxide results in decreased expression of CAT protein]; Pioglitazone inhibits the reaction [Arsenic Trioxide results in decreased expression of CAT protein] Arsenic Trioxide results in increased activity of CAT protein
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CTD |
PMID:11749846 PMID:16214333 PMID:17258074 PMID:18332854 PMID:18336854 PMID:18387645 PMID:18588940 PMID:18715643 PMID:20171736 PMID:21308489 PMID:21689642 PMID:22590507 PMID:23023136 PMID:23082001 PMID:23283742 PMID:24095718 PMID:25542264 PMID:26184899 PMID:26560635 PMID:27713174 PMID:28209094 PMID:28391263 PMID:28803342 PMID:28978146 PMID:29130132 PMID:29223816 PMID:29467594 PMID:29751151 PMID:30012499 PMID:30090573 PMID:31846860 PMID:32919218 PMID:32920515 PMID:33173984 PMID:33603344 PMID:33634982 PMID:33846815 PMID:34062077 PMID:34333357 PMID:35088608 PMID:35317438 PMID:37730986 PMID:38781725 More...
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NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:110,297,342...110,329,526
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| G
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Catsper4
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cation channel, sperm associated 4
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increases expression
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ISO
|
Arsenic Trioxide results in increased expression of CATSPER4 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 5:151,711,415...151,731,083
Ensembl chr 5:151,711,194...151,730,750
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| G
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Cav1
|
caveolin 1
|
decreases expression increases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of CAV1 mRNA; Arsenic Trioxide results in decreased expression of CAV1 protein Arsenic Trioxide results in increased expression of CAV1 mRNA; Arsenic Trioxide results in increased expression of CAV1 protein
|
CTD |
PMID:15725085 PMID:17512576 PMID:22521957 PMID:26238599 PMID:28521025 |
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NCBI chr 4:46,606,538...46,639,616
Ensembl chr 4:46,600,738...46,639,740
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|
| G
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Cav2
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caveolin 2
|
increases expression multiple interactions decreases expression
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ISO
|
Arsenic Trioxide results in increased expression of CAV2 mRNA [Tretinoin co-treated with Arsenic Trioxide] results in increased expression of CAV2 mRNA Arsenic Trioxide results in decreased expression of CAV2 mRNA
|
CTD |
PMID:15725085 PMID:15761015 PMID:15894607 |
|
NCBI chr 4:46,582,681...46,590,058
Ensembl chr 4:46,582,096...46,591,425
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|
| G
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Cav3
|
caveolin 3
|
increases expression multiple interactions
|
EXP
|
Arsenic Trioxide results in increased expression of CAV3 mRNA Phloretin inhibits the reaction [Arsenic Trioxide results in decreased expression of CAV3 mRNA]
|
CTD |
PMID:34037972 |
|
NCBI chr 4:147,137,993...147,153,967
Ensembl chr 4:147,137,797...147,153,967
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|
| G
|
Cavin2
|
caveolae associated protein 2
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of CAVIN2 mRNA
|
CTD |
PMID:26705709 |
|
NCBI chr 9:57,794,007...57,806,024
Ensembl chr 9:57,794,019...57,806,024
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|
| G
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Cavin3
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caveolae associated protein 3
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of CAVIN3 protein
|
CTD |
PMID:25419056 |
|
NCBI chr 1:169,238,384...169,239,973
Ensembl chr 1:169,238,384...169,239,981
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|
| G
|
Cbl
|
Cbl proto-oncogene
|
multiple interactions increases expression
|
ISO
|
[Bortezomib results in decreased activity of CBL protein] promotes the reaction [Arsenic Trioxide results in increased activity of AKT1 protein] Arsenic Trioxide results in increased expression of CBL protein
|
CTD |
PMID:19457607 |
|
NCBI chr 8:53,384,656...53,468,067
Ensembl chr 8:53,384,656...53,468,067
|
|
| G
|
Cbln4
|
cerebellin 4 precursor
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to CBLN4 protein]
|
CTD |
PMID:26598702 |
|
NCBI chr 3:181,218,046...181,225,600
Ensembl chr 3:181,218,046...181,225,600
|
|
| G
|
Cbr1
|
carbonyl reductase 1
|
decreases response to substance increases expression
|
ISO
|
CBR1 protein results in decreased susceptibility to Arsenic Trioxide Arsenic Trioxide results in increased expression of CBR1 mRNA
|
CTD |
PMID:22719067 |
|
NCBI chr11:46,346,405...46,348,815
Ensembl chr11:46,378,411...46,381,104 Ensembl chr11:46,378,411...46,381,104
|
|
| G
|
Cbr4
|
carbonyl reductase 4
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of CBR4 mRNA
|
CTD |
PMID:27829220 |
|
NCBI chr16:33,625,734...33,695,067
Ensembl chr16:33,617,399...33,656,832
|
|
| G
|
Cbx4
|
chromobox 4
|
increases sumoylation
|
ISO
|
Arsenic Trioxide results in increased sumoylation of CBX4 protein
|
CTD |
PMID:28318385 |
|
NCBI chr10:104,835,685...104,841,727
Ensembl chr10:104,835,685...104,841,727
|
|
| G
|
Cbx7
|
chromobox 7
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of CBX7 mRNA
|
CTD |
PMID:22521957 |
|
NCBI chr 7:113,341,030...113,358,716
Ensembl chr 7:113,341,030...113,358,346
|
|
| G
|
Cby1
|
chibby 1, beta catenin antagonist
|
increases expression multiple interactions
|
ISO
|
Arsenic Trioxide results in increased expression of CBY1 mRNA Metformin inhibits the reaction [Arsenic Trioxide results in increased expression of CBY1 mRNA]
|
CTD |
PMID:29095437 |
|
NCBI chr 7:113,097,220...113,103,831
|
|
| G
|
Cc2d2a
|
coiled-coil and C2 domain containing 2A
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of CC2D2A mRNA
|
CTD |
PMID:35676786 |
|
NCBI chr14:71,563,835...71,648,352
Ensembl chr14:71,563,835...71,648,331
|
|
| G
|
Cc2d2b
|
coiled-coil and C2 domain containing 2B
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to CC2D2B protein]
|
CTD |
PMID:26598702 |
|
NCBI chr 1:249,509,371...249,608,894
Ensembl chr 1:249,511,389...249,606,142
|
|
| G
|
Ccdc14
|
coiled-coil domain containing 14
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of CCDC14 mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr11:79,557,267...79,593,128
Ensembl chr11:79,557,274...79,593,285
|
|
| G
|
Ccdc150
|
coiled-coil domain containing 150
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of CCDC150 mRNA
|
CTD |
PMID:21461292 |
|
NCBI chr 9:63,287,962...63,403,644
Ensembl chr 9:63,288,000...63,391,670
|
|
| G
|
Ccdc198
|
coiled-coil domain containing 198
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of CCDC198 mRNA
|
CTD |
PMID:15761015 |
|
NCBI chr15:24,979,764...25,006,608
Ensembl chr15:24,979,531...25,006,542
|
|
| G
|
Ccdc28b
|
coiled coil domain containing 28B
|
increases response to substance
|
ISO
|
CCDC28B protein results in increased susceptibility to Arsenic Trioxide
|
CTD |
PMID:20707922 |
|
NCBI chr 5:147,246,627...147,251,629
Ensembl chr 5:147,246,628...147,251,629
|
|
| G
|
Ccdc32
|
coiled-coil domain containing 32
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of CCDC32 mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr 3:126,452,293...126,464,845
Ensembl chr 3:126,452,304...126,472,778
|
|
| G
|
Ccdc47
|
coiled-coil domain containing 47
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of CCDC47 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr10:91,630,101...91,648,626
Ensembl chr10:91,630,106...91,648,626
|
|
| G
|
Ccdc6
|
coiled-coil domain containing 6
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to CCDC6 protein]
|
CTD |
PMID:26598702 |
|
NCBI chr20:18,431,243...18,527,227
Ensembl chr20:18,431,243...18,527,227
|
|
| G
|
Ccdc85b
|
coiled-coil domain containing 85B
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of DIPA mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 1:212,192,979...212,193,994
Ensembl chr 1:212,189,468...212,196,911
|
|
| G
|
Ccdc86
|
coiled-coil domain containing 86
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of CCDC86 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 1:217,015,059...217,021,439
Ensembl chr 1:217,014,848...217,021,468
|
|
| G
|
Ccdc92
|
coiled-coil domain containing 92
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to CCDC92 protein]
|
CTD |
PMID:26598702 |
|
NCBI chr12:37,457,676...37,484,080
Ensembl chr12:37,457,068...37,484,327
|
|
| G
|
Ccl1
|
C-C motif chemokine ligand 1
|
multiple interactions
|
ISO
|
[Arsenic Trioxide co-treated with Tretinoin] results in increased expression of CCL1 mRNA
|
CTD |
PMID:19828696 |
|
NCBI chr10:67,625,962...67,628,740
Ensembl chr10:67,625,962...67,628,790
|
|
| G
|
Ccl11
|
C-C motif chemokine ligand 11
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of CCL11 protein
|
CTD |
PMID:37166470 |
|
NCBI chr10:67,525,975...67,530,576
Ensembl chr10:67,525,862...67,530,575
|
|
| G
|
Ccl2
|
C-C motif chemokine ligand 2
|
multiple interactions increases expression affects expression
|
ISO EXP
|
[Arsenic Trioxide co-treated with Tretinoin] results in increased expression of CCL2 mRNA; [Arsenic Trioxide co-treated with Tretinoin] results in increased expression of CCL2 protein; [Tretinoin co-treated with Arsenic Trioxide] results in increased expression of CCL2 mRNA Thioctic Acid inhibits the reaction [Arsenic Trioxide results in increased expression of CCL2 mRNA] Arsenic Trioxide results in increased expression of CCL2 mRNA; Arsenic Trioxide results in increased expression of CCL2 protein Arsenic Trioxide affects the expression of CCL2 mRNA Phloretin inhibits the reaction [Arsenic Trioxide results in increased expression of CCL2 protein]
|
CTD |
PMID:15761015 PMID:15894607 PMID:18231732 PMID:19828696 PMID:20458559 PMID:22488045 PMID:31734849 PMID:34037972 PMID:37166470 More...
|
|
NCBI chr10:67,503,077...67,504,875
Ensembl chr10:67,503,077...67,504,875
|
|
| G
|
Ccl20
|
C-C motif chemokine ligand 20
|
multiple interactions
|
ISO
|
[Arsenic Trioxide co-treated with Tretinoin] results in increased expression of CCL20 mRNA
|
CTD |
PMID:19828696 |
|
NCBI chr 9:91,837,139...91,839,736
Ensembl chr 9:91,836,946...91,839,736
|
|
| G
|
Ccl22
|
C-C motif chemokine ligand 22
|
multiple interactions decreases expression
|
ISO
|
[Arsenic Trioxide co-treated with Tretinoin] results in increased expression of CCL22 mRNA; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in decreased expression of CCL22 mRNA]
|
CTD |
PMID:19128835 PMID:19350554 PMID:19828696 |
|
NCBI chr19:10,263,589...10,270,359
Ensembl chr19:10,263,589...10,270,359
|
|
| G
|
Ccl24
|
C-C motif chemokine ligand 24
|
multiple interactions decreases expression
|
ISO
|
[Arsenic Trioxide co-treated with Tretinoin] results in increased expression of CCL24 mRNA Arsenic Trioxide results in decreased expression of CCL24 mRNA
|
CTD |
PMID:19828696 PMID:39716349 |
|
NCBI chr12:26,737,423...26,741,420
Ensembl chr12:26,737,439...26,750,924
|
|
| G
|
Ccl27
|
C-C motif chemokine ligand 27
|
decreases expression multiple interactions
|
ISO
|
Arsenic Trioxide results in decreased expression of CCL27A mRNA Metformin inhibits the reaction [Arsenic Trioxide results in decreased expression of CCL27A mRNA]
|
CTD |
PMID:29095437 |
|
NCBI chr 5:61,737,261...61,744,375
Ensembl chr 5:61,737,261...61,743,522
|
|
| G
|
Ccl3
|
C-C motif chemokine ligand 3
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of CCL3 mRNA
|
CTD |
PMID:19128835 |
|
NCBI chr10:68,948,889...68,950,439
Ensembl chr10:68,948,889...68,950,439
|
|
| G
|
Ccl4
|
C-C motif chemokine ligand 4
|
multiple interactions
|
ISO
|
[Arsenic Trioxide co-treated with Tretinoin] results in increased expression of CCL4 mRNA
|
CTD |
PMID:19828696 |
|
NCBI chr10:68,963,893...68,965,728
Ensembl chr10:68,950,289...68,965,722
|
|
| G
|
Ccl5
|
C-C motif chemokine ligand 5
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of CCL5 protein
|
CTD |
PMID:37166470 |
|
NCBI chr10:68,820,330...68,824,906
Ensembl chr10:68,738,651...68,824,884
|
|
| G
|
Ccl7
|
C-C motif chemokine ligand 7
|
multiple interactions increases expression
|
ISO
|
[Arsenic Trioxide co-treated with Tretinoin] results in increased expression of CCL7 mRNA; [Arsenic Trioxide co-treated with Tretinoin] results in increased expression of CCL7 protein Arsenic Trioxide results in increased expression of CCL7 mRNA; Arsenic Trioxide results in increased expression of CCL7 protein
|
CTD |
PMID:19828696 PMID:37166470 |
|
NCBI chr10:67,514,095...67,515,945
Ensembl chr10:67,514,091...67,515,947
|
|
| G
|
Ccl9
|
C-C motif chemokine ligand 9
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of CCL15 mRNA
|
CTD |
PMID:15761015 |
|
NCBI chr10:68,863,994...68,868,928
Ensembl chr10:68,863,995...68,868,877
|
|
| G
|
Ccn1
|
cellular communication network factor 1
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of CCN1 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 2:237,222,730...237,225,689
Ensembl chr 2:237,222,432...237,225,883
|
|
| G
|
Ccn2
|
cellular communication network factor 2
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [TGFB1 protein results in increased expression of CCN2 mRNA]
|
CTD |
PMID:24762191 |
|
NCBI chr 1:22,621,498...22,624,614
Ensembl chr 1:22,621,501...22,624,976
|
|
| G
|
Ccn4
|
cellular communication network factor 4
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of CCN4 mRNA; Arsenic Trioxide results in decreased expression of WISP1 mRNA
|
CTD |
PMID:20458559 PMID:26705709 PMID:39716349 |
|
NCBI chr 7:100,534,578...100,566,287
Ensembl chr 7:100,534,505...100,563,094
|
|
| G
|
Ccn5
|
cellular communication network factor 5
|
decreases response to substance
|
ISO
|
CCN5 protein results in decreased susceptibility to Arsenic Trioxide
|
CTD |
PMID:20707922 |
|
NCBI chr 3:172,910,670...172,922,064
Ensembl chr 3:172,910,681...172,922,062
|
|
| G
|
Ccna1
|
cyclin A1
|
decreases expression multiple interactions
|
ISO
|
Arsenic Trioxide results in decreased expression of CCNA1 mRNA Arsenic Trioxide inhibits the reaction [PDGFB protein results in increased expression of CCNA1 protein]
|
CTD |
PMID:15761015 PMID:35276128 |
|
NCBI chr 2:141,383,352...141,428,205
Ensembl chr 2:141,382,468...141,393,300
|
|
| G
|
Ccna2
|
cyclin A2
|
affects expression decreases expression
|
ISO
|
Arsenic Trioxide affects the expression of CCNA2 mRNA Arsenic Trioxide results in decreased expression of CCNA2 mRNA; Arsenic Trioxide results in decreased expression of CCNA2 protein
|
CTD |
PMID:12480548 PMID:20458559 PMID:25174355 PMID:28786057 |
|
NCBI chr 2:121,355,363...121,361,762
Ensembl chr 2:121,355,363...121,361,701
|
|
| G
|
Ccnb1
|
cyclin B1
|
decreases expression multiple interactions increases expression
|
ISO EXP
|
Arsenic Trioxide results in decreased expression of CCNB1 mRNA; Arsenic Trioxide results in decreased expression of CCNB1 protein 4-amino-1,8-naphthalimide inhibits the reaction [Arsenic Trioxide results in decreased expression of CCNB1 mRNA]; 4-amino-1,8-naphthalimide inhibits the reaction [Arsenic Trioxide results in decreased expression of CCNB1 protein]; [Arsenic Trioxide co-treated with Oxygen deficiency] results in decreased expression of CCNB1 mRNA; [Arsenic Trioxide co-treated with Oxygen deficiency] results in decreased expression of CCNB1 protein; [Erlotinib Hydrochloride co-treated with Arsenic Trioxide] results in decreased expression of CCNB1 mRNA; CAB39L protein alternative form inhibits the reaction [Arsenic Trioxide results in decreased expression of CCNB1 protein] Arsenic Trioxide results in increased expression of CCNB1 mRNA; Arsenic Trioxide results in increased expression of CCNB1 protein
|
CTD |
PMID:12181429 PMID:12783709 PMID:12883267 PMID:17530438 PMID:19825857 PMID:20458559 PMID:23337567 PMID:25499136 PMID:29059232 PMID:29274334 More...
|
|
NCBI chr 2:33,646,252...33,655,225
Ensembl chr 2:33,646,252...33,655,225
|
|
| G
|
Ccnb2
|
cyclin B2
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of CCNB2 mRNA
|
CTD |
PMID:17547211 |
|
NCBI chr 8:79,968,459...79,981,717
Ensembl chr 8:79,968,465...79,981,682
|
|
| G
|
Ccnd1
|
cyclin D1
|
multiple interactions decreases response to substance increases expression decreases activity decreases expression affects response to substance decreases methylation
|
ISO
|
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Arsenic Trioxide results in increased expression of CCND1 protein]; 9-methoxy-2-methylellipticinium acetate inhibits the reaction [Arsenic Trioxide results in increased expression of CCND1 protein]; [Arsenic Trioxide co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CCND1 mRNA; [Arsenic Trioxide results in increased phosphorylation of and results in increased activity of CHUK protein] which results in increased phosphorylation of and results in increased ubiquitination of and results in increased degradation of CCND1 protein; [Arsenic Trioxide results in increased phosphorylation of and results in increased activity of GSK3B protein] which results in increased phosphorylation of and results in increased ubiquitination of and results in increased degradation of CCND1 protein; [Arsenic Trioxide results in increased phosphorylation of and results in increased activity of IKBKB protein] which results in increased phosphorylation of and results in increased ubiquitination of and results in increased degradation of CCND1 protein; [BIBR 1532 co-treated with Arsenic Trioxide] affects the expression of CCND1 mRNA; [Genistein co-treated with Arsenic Trioxide] results in decreased expression of CCND1 protein; [ruxolitinib co-treated with Arsenic Trioxide] results in decreased expression of CCND1 mRNA; AKT1 protein affects the reaction [Arsenic Trioxide results in increased expression of CCND1 protein]; Arsenic Trioxide affects the reaction [KEAP1 protein results in increased expression of CCND1 protein]; Arsenic Trioxide promotes the reaction [Sorafenib results in decreased expression of CCND1 protein]; Arsenic Trioxide promotes the reaction [Tretinoin results in decreased expression of CCND1 protein]; CAB39L protein alternative form inhibits the reaction [Arsenic Trioxide results in decreased expression of CCND1 protein]; KEAP1 protein inhibits the reaction [Arsenic Trioxide results in decreased expression of CCND1 mRNA]; MAPK1 protein affects the reaction [Arsenic Trioxide results in increased expression of CCND1 protein]; MAPK3 protein affects the reaction [Arsenic Trioxide results in increased expression of CCND1 protein]; Sorafenib promotes the reaction [Arsenic Trioxide results in decreased expression of CCND1 protein]; Tretinoin promotes the reaction [Arsenic Trioxide results in decreased expression of CCND1 protein] CCND1 mRNA results in decreased susceptibility to Arsenic Trioxide Arsenic Trioxide results in increased expression of CCND1 mRNA; Arsenic Trioxide results in increased expression of CCND1 protein Arsenic Trioxide results in decreased activity of CCND1 promoter Arsenic Trioxide results in decreased expression of CCND1 mRNA; Arsenic Trioxide results in decreased expression of CCND1 protein CCND1 mRNA affects the susceptibility to Arsenic Trioxide Arsenic Trioxide results in decreased methylation of CCND1 promoter
|
CTD |
PMID:12480548 PMID:12883267 PMID:15073043 PMID:17530438 PMID:17617380 PMID:18922899 PMID:19128835 PMID:20435036 PMID:20458559 PMID:20723298 PMID:20862710 PMID:21078540 PMID:22362285 PMID:22684020 PMID:23255470 PMID:23440206 PMID:23911876 PMID:23949314 PMID:25416439 PMID:25945059 PMID:28565807 PMID:28901456 PMID:29059232 PMID:29159499 PMID:29442453 PMID:30012499 PMID:30093655 PMID:32645343 PMID:34413873 PMID:36442592 More...
|
|
NCBI chr 1:209,518,288...209,527,986
Ensembl chr 1:209,518,288...209,527,810
|
|
| G
|
Ccnd2
|
cyclin D2
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of CCND2 mRNA
|
CTD |
PMID:15073043 |
|
NCBI chr 4:161,653,048...161,675,422
Ensembl chr 4:161,653,048...161,680,301 Ensembl chr 4:161,653,048...161,680,301
|
|
| G
|
Ccnd3
|
cyclin D3
|
increases expression decreases expression
|
ISO
|
Arsenic Trioxide results in increased expression of CCND3 mRNA Arsenic Trioxide results in decreased expression of CCND3 mRNA
|
CTD |
PMID:20458559 PMID:29633893 PMID:39716349 |
|
NCBI chr 9:20,891,696...20,987,199
Ensembl chr 9:20,891,704...20,987,033
|
|
| G
|
Ccne1
|
cyclin E1
|
affects expression multiple interactions decreases methylation decreases expression increases expression
|
ISO
|
Arsenic Trioxide affects the expression of CCNE1 protein Arsenic Trioxide promotes the reaction [CCNE1 protein binds to CDKN1A protein]; TP53 protein promotes the reaction [Arsenic Trioxide results in decreased expression of CCNE1 protein] Arsenic Trioxide results in decreased methylation of CCNE1 promoter Arsenic Trioxide results in decreased expression of CCNE1 mRNA; Arsenic Trioxide results in decreased expression of CCNE1 protein Arsenic Trioxide results in increased expression of CCNE1 mRNA; Arsenic Trioxide results in increased expression of CCNE1 protein
|
CTD |
PMID:10850458 PMID:12480548 PMID:12962562 PMID:19236751 PMID:29159499 PMID:29633893 PMID:34042274 PMID:34413873 More...
|
|
NCBI chr 1:99,918,672...99,927,986
Ensembl chr 1:99,918,674...99,927,822
|
|
| G
|
Ccnf
|
cyclin F
|
increases expression decreases methylation decreases expression
|
ISO
|
Arsenic Trioxide results in increased expression of CCNF mRNA Arsenic Trioxide results in decreased methylation of CCNF promoter Arsenic Trioxide results in decreased expression of CCNF mRNA; Arsenic Trioxide results in decreased expression of CCNF protein
|
CTD |
PMID:17530438 PMID:29159499 |
|
NCBI chr10:13,757,884...13,783,669
Ensembl chr10:13,758,421...13,783,837
|
|
| G
|
Ccng1
|
cyclin G1
|
increases expression multiple interactions
|
EXP
|
Arsenic Trioxide results in increased expression of CCNG1 mRNA pifithrin inhibits the reaction [Arsenic Trioxide results in increased expression of CCNG1 mRNA]
|
CTD |
PMID:17487067 |
|
NCBI chr10:25,678,503...25,684,876
Ensembl chr10:25,677,885...25,683,766
|
|
| G
|
Ccng2
|
cyclin G2
|
increases expression multiple interactions
|
ISO
|
Arsenic Trioxide results in increased expression of CCNG2 mRNA [pifithrin co-treated with Arsenic Trioxide] results in increased expression of CCNG2 mRNA
|
CTD |
PMID:20458559 PMID:24356939 PMID:25424538 PMID:35030298 |
|
NCBI chr14:15,088,694...15,097,190
Ensembl chr14:15,088,695...15,096,206
|
|
| G
|
Ccnh
|
cyclin H
|
increases expression decreases expression
|
ISO
|
Arsenic Trioxide results in increased expression of CCNH mRNA Arsenic Trioxide results in decreased expression of CCNH mRNA
|
CTD |
PMID:11940349 PMID:17530438 |
|
NCBI chr 2:17,570,449...17,591,078
Ensembl chr 2:17,570,263...17,614,860
|
|
| G
|
Ccnjl
|
cyclin J-like
|
decreases expression increases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of CCNJL mRNA Arsenic Trioxide results in increased expression of CCNJL mRNA
|
CTD |
PMID:35676786 PMID:39716349 |
|
NCBI chr10:28,497,144...28,554,877
Ensembl chr10:28,496,990...28,554,877
|
|
| G
|
Ccno
|
cyclin O
|
decreases response to substance
|
ISO
|
CCNO protein results in decreased susceptibility to Arsenic Trioxide
|
CTD |
PMID:20707922 |
|
NCBI chr 2:46,364,074...46,367,113
Ensembl chr 2:46,350,717...46,367,113
|
|
| G
|
Ccpg1
|
cell cycle progression 1
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of CCPG1 mRNA
|
CTD |
PMID:20471514 |
|
NCBI chr 8:82,600,677...82,633,082
Ensembl chr 8:82,600,536...82,660,246
|
|
| G
|
Ccr1
|
C-C motif chemokine receptor 1
|
multiple interactions
|
ISO
|
[Tretinoin co-treated with Arsenic Trioxide] results in increased expression of CCR1 mRNA
|
CTD |
PMID:15894607 |
|
NCBI chr 8:132,433,711...132,439,266
Ensembl chr 8:132,431,592...132,439,374
|
|
| G
|
Ccr6
|
C-C motif chemokine receptor 6
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of CCR6 mRNA; Arsenic Trioxide results in decreased expression of CCR6 protein
|
CTD |
PMID:34108876 |
|
NCBI chr 1:55,022,037...55,055,857
Ensembl chr 1:55,021,833...55,046,059
|
|
| G
|
Ccr8
|
C-C motif chemokine receptor 8
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of CCR8 mRNA
|
CTD |
PMID:27829220 |
|
NCBI chr 8:128,703,966...128,705,926
Ensembl chr 8:128,702,349...128,705,955
|
|
| G
|
Cct2
|
chaperonin containing TCP1 subunit 2
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of CCT2 protein
|
CTD |
PMID:19364129 |
|
NCBI chr 7:54,578,654...54,591,428
Ensembl chr 7:54,578,663...54,592,977
|
|
| G
|
Cct3
|
chaperonin containing TCP1 subunit 3
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of CCT3 protein
|
CTD |
PMID:19364129 |
|
NCBI chr 2:176,063,529...176,088,180
Ensembl chr 2:176,063,526...176,089,925
|
|
| G
|
Cct6a
|
chaperonin containing TCP1 subunit 6A
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of CCT6A protein
|
CTD |
PMID:19364129 |
|
NCBI chr12:32,508,842...32,519,072
Ensembl chr12:32,508,675...32,519,119
|
|
| G
|
Cct7
|
chaperonin containing TCP1 subunit 7
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to CCT7 protein]
|
CTD |
PMID:26598702 |
|
NCBI chr 4:119,546,730...119,563,973
Ensembl chr 4:119,546,730...119,563,973
|
|
| G
|
Cct8
|
chaperonin containing TCP1 subunit 8
|
increases expression multiple interactions
|
ISO
|
Arsenic Trioxide results in increased expression of CCT8 mRNA Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to CCT8 protein]
|
CTD |
PMID:20458559 PMID:26598702 |
|
NCBI chr11:40,196,619...40,208,328
Ensembl chr11:40,196,619...40,208,328
|
|
| G
|
Cd14
|
CD14 molecule
|
multiple interactions increases expression decreases expression
|
ISO
|
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Gefitinib promotes the reaction [Arsenic Trioxide results in increased expression of CD14 protein]]; [Gefitinib promotes the reaction Arsenic Trioxide] which results in increased expression of CD14 mRNA; Gefitinib promotes the reaction [Arsenic Trioxide results in increased expression of CD14 protein]; SB 203580 inhibits the reaction [Gefitinib promotes the reaction [Arsenic Trioxide results in increased expression of CD14 protein]] Arsenic Trioxide results in increased expression of CD14 mRNA Arsenic Trioxide results in decreased expression of CD14 mRNA Arsenic Trioxide results in increased expression of CD14 mRNA; Arsenic Trioxide results in increased expression of CD14 protein
|
CTD |
PMID:15073043 PMID:20226526 PMID:22521957 PMID:23911876 |
|
NCBI chr18:28,609,558...28,611,409
Ensembl chr18:28,608,883...28,611,292
|
|
| G
|
Cd164
|
CD164 molecule
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of CD164 mRNA
|
CTD |
PMID:19128835 |
|
NCBI chr20:46,606,439...46,618,015
Ensembl chr20:46,606,107...46,638,649
|
|
| G
|
Cd177
|
CD177 molecule
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of CD177 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 1:89,467,926...89,488,490
Ensembl chr 1:89,467,926...89,488,443
|
|
| G
|
Cd1d1
|
CD1d1 molecule
|
decreases expression multiple interactions
|
ISO
|
Arsenic Trioxide results in decreased expression of CD1D mRNA [Arsenic Trioxide co-treated with Tretinoin] results in increased expression of CD1D mRNA
|
CTD |
PMID:15761015 PMID:38179723 |
|
NCBI chr 2:174,721,522...174,725,029
Ensembl chr 2:174,721,522...174,725,029
|
|
| G
|
Cd22
|
CD22 molecule
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of CD22 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 1:95,243,785...95,270,430
Ensembl chr 1:95,244,868...95,259,730
|
|
| G
|
Cd24
|
CD24 molecule
|
multiple interactions increases expression
|
ISO
|
SOX2 protein affects the reaction [Arsenic Trioxide results in increased expression of CD24 protein] Arsenic Trioxide results in increased expression of CD24 mRNA; Arsenic Trioxide results in increased expression of CD24 protein
|
CTD |
PMID:29396848 |
|
NCBI chr20:48,655,549...48,661,786
Ensembl chr20:48,655,805...48,661,785
|
|
| G
|
Cd27
|
CD27 molecule
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of CD27 mRNA
|
CTD |
PMID:17530438 |
|
NCBI chr 4:159,716,932...159,721,823
Ensembl chr 4:159,716,935...159,721,823
|
|
| G
|
Cd274
|
CD274 molecule
|
multiple interactions increases phosphorylation
|
ISO
|
[CpG ODN 2216 co-treated with Arsenic Trioxide] results in increased expression of CD274 protein; Arsenic Trioxide promotes the reaction [CPG-oligonucleotide results in increased expression of CD274 protein] Arsenic Trioxide results in increased phosphorylation of CD274 protein STING1 promotes the reaction [Arsenic Trioxide results in increased phosphorylation of CD274 protein]
|
CTD |
PMID:32642412 PMID:38684648 |
|
NCBI chr 1:236,526,215...236,549,956
Ensembl chr 1:236,496,463...236,549,951
|
|
| G
|
Cd28
|
Cd28 molecule
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of CD28 mRNA
|
CTD |
PMID:34108876 |
|
NCBI chr 9:69,660,316...69,689,192
Ensembl chr 9:69,545,326...69,689,192
|
|
| G
|
Cd34
|
CD34 molecule
|
multiple interactions decreases expression
|
ISO
|
[Tetradecanoylphorbol Acetate co-treated with Arsenic Trioxide] results in increased expression of CD34 mRNA; [Tetradecanoylphorbol Acetate co-treated with Arsenic Trioxide] results in increased expression of CD34 protein; Arsenic Trioxide promotes the reaction [Homoharringtonine results in decreased expression of CD34 mRNA] Arsenic Trioxide results in decreased expression of CD34 mRNA
|
CTD |
PMID:18922899 PMID:31307525 |
|
NCBI chr13:109,008,786...109,029,317
Ensembl chr13:109,008,623...109,029,315
|
|
| G
|
Cd36
|
CD36 molecule
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CD36 mRNA]; Thioctic Acid inhibits the reaction [Arsenic Trioxide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CD36 mRNA]] Arsenic Trioxide affects the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of CD36 mRNA]; Arsenic Trioxide affects the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of CD36 protein]
|
CTD |
PMID:21315065 PMID:38237221 |
|
NCBI chr 4:18,209,088...18,302,142
|
|
| G
|
Cd38
|
CD38 molecule
|
increases response to substance increases expression multiple interactions
|
ISO
|
CD38 results in increased susceptibility to Arsenic Trioxide Arsenic Trioxide results in increased expression of CD38 mRNA [Arsenic Trioxide co-treated with Homoharringtonine] results in increased expression of CD38 mRNA; [Arsenic Trioxide co-treated with Tretinoin] results in increased expression of CD38 mRNA
|
CTD |
PMID:18297255 PMID:31307525 PMID:38179723 |
|
NCBI chr14:71,384,532...71,424,794
Ensembl chr14:71,384,532...71,424,505
|
|
| G
|
Cd40
|
CD40 molecule
|
multiple interactions increases expression
|
ISO
|
[Arsenic Trioxide co-treated with Curcumin] results in increased expression of CD40 protein Arsenic Trioxide results in increased expression of CD40 protein
|
CTD |
PMID:27430728 |
|
NCBI chr 3:174,209,113...174,224,592
Ensembl chr 3:174,209,719...174,224,847
|
|
| G
|
Cd40lg
|
CD40 ligand
|
multiple interactions increases expression
|
ISO
|
[Arsenic Trioxide co-treated with Curcumin] results in increased expression of CD40LG protein Arsenic Trioxide results in increased expression of CD40LG protein
|
CTD |
PMID:27430728 |
|
NCBI chr X:140,164,341...140,176,057
Ensembl chr X:140,164,302...140,176,475
|
|
| G
|
Cd44
|
CD44 molecule
|
multiple interactions decreases expression
|
ISO
|
[Tretinoin co-treated with Arsenic Trioxide] results in increased expression of CD44 mRNA Arsenic Trioxide results in decreased expression of CD44 mRNA; Arsenic Trioxide results in decreased expression of CD44 mRNA alternative form; Arsenic Trioxide results in decreased expression of CD44 protein; Arsenic Trioxide results in decreased expression of CD44 protein alternative form
|
CTD |
PMID:15553829 PMID:15894607 PMID:19804631 PMID:22391160 PMID:23098472 |
|
NCBI chr 3:109,610,824...109,699,776
Ensembl chr 3:109,612,054...109,699,424
|
|
| G
|
Cd52
|
CD52 molecule
|
decreases expression multiple interactions increases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of CD52 mRNA [Tretinoin co-treated with Arsenic Trioxide] results in increased expression of CD52 mRNA Arsenic Trioxide results in increased expression of CD52 mRNA
|
CTD |
PMID:10673743 PMID:15761015 PMID:15894607 PMID:19128835 |
|
NCBI chr 5:151,603,537...151,605,096
Ensembl chr 5:151,603,524...151,605,086
|
|
| G
|
Cd53
|
Cd53 molecule
|
multiple interactions
|
ISO
|
[Tretinoin co-treated with Arsenic Trioxide] results in increased expression of CD53 mRNA
|
CTD |
PMID:15894607 |
|
NCBI chr 2:197,040,369...197,087,925
Ensembl chr 2:197,040,369...197,218,593
|
|
| G
|
Cd55
|
CD55 molecule (Cromer blood group)
|
decreases expression increases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of CD55 mRNA Arsenic Trioxide results in increased expression of CD55 mRNA
|
CTD |
PMID:29633893 PMID:36801614 |
|
NCBI chr13:44,409,574...44,438,913
Ensembl chr13:44,409,587...44,438,107
|
|
| G
|
Cd5l
|
Cd5 molecule-like
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of CD5L mRNA
|
CTD |
PMID:35676786 |
|
NCBI chr 2:175,088,915...175,099,928
Ensembl chr 2:175,088,884...175,099,926
|
|
| G
|
Cd70
|
Cd70 molecule
|
increases expression decreases expression
|
ISO EXP
|
Arsenic Trioxide results in increased expression of CD70 mRNA Arsenic Trioxide results in decreased expression of CD70 mRNA
|
CTD |
PMID:15761015 PMID:17530438 PMID:19730151 |
|
NCBI chr 9:2,093,540...2,096,692
Ensembl chr 9:2,086,848...2,096,692
|
|
| G
|
Cd74
|
CD74 molecule
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of CD74 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr18:56,527,071...56,536,406
Ensembl chr18:56,527,132...56,536,410
|
|
| G
|
Cd80
|
Cd80 molecule
|
multiple interactions
|
ISO
|
[CpG ODN 2216 co-treated with Arsenic Trioxide] results in decreased expression of CD80 protein; Arsenic Trioxide inhibits the reaction [CpG ODN 2216 results in increased expression of CD80 protein]
|
CTD |
PMID:32642412 |
|
NCBI chr11:75,760,073...75,798,978
Ensembl chr11:75,760,147...75,797,540
|
|
| G
|
Cd84
|
CD84 molecule
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of CD84 mRNA
|
CTD |
PMID:24356939 |
|
NCBI chr13:86,859,979...86,899,984
Ensembl chr13:86,859,990...86,894,318
|
|
| G
|
Cd86
|
CD86 molecule
|
increases expression decreases expression multiple interactions
|
ISO
|
Arsenic Trioxide results in increased expression of CD86 mRNA Arsenic Trioxide results in decreased expression of CD86 mRNA [CpG ODN 2216 co-treated with Arsenic Trioxide] results in decreased expression of CD86 protein; Arsenic Trioxide inhibits the reaction [CpG ODN 2216 results in increased expression of CD86 protein]
|
CTD |
PMID:15761015 PMID:20458559 PMID:32642412 |
|
NCBI chr11:77,647,565...77,706,178
Ensembl chr11:77,647,600...77,725,361
|
|
| G
|
Cd9
|
CD9 molecule
|
decreases response to substance
|
ISO
|
CD9 protein results in decreased susceptibility to Arsenic Trioxide
|
CTD |
PMID:20707922 |
|
NCBI chr 4:159,942,553...159,975,463
Ensembl chr 4:159,942,560...159,975,444
|
|
| G
|
Cd96
|
CD96 molecule
|
multiple interactions decreases expression
|
ISO
|
[Arsenic Trioxide co-treated with Homoharringtonine] results in decreased expression of CD96 mRNA Arsenic Trioxide results in decreased expression of CD96 mRNA
|
CTD |
PMID:31307525 |
|
NCBI chr11:68,164,926...68,239,266
Ensembl chr11:68,164,872...68,241,937
|
|
| G
|
Cdc20
|
cell division cycle 20
|
decreases expression multiple interactions increases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of CDC20 mRNA; Arsenic Trioxide results in decreased expression of CDC20 protein [Arsenic Trioxide co-treated with Paclitaxel] promotes the reaction [BUB1B protein binds to CDC20 protein] Arsenic Trioxide results in increased expression of CDC20 mRNA
|
CTD |
PMID:19781537 PMID:20862710 PMID:29950208 |
|
NCBI chr 5:137,251,596...137,255,799
Ensembl chr 5:137,251,596...137,255,799
|
|
| G
|
Cdc23
|
cell division cycle 23
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of CDC23 mRNA
|
CTD |
PMID:20862710 |
|
NCBI chr18:26,511,019...26,534,872
Ensembl chr18:26,510,355...26,532,646
|
|
| G
|
Cdc25a
|
cell division cycle 25A
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of CDC25A mRNA; Arsenic Trioxide results in increased expression of CDC25A protein
|
CTD |
PMID:20862710 PMID:23255470 PMID:29633893 |
|
NCBI chr 8:118,742,824...118,761,190
Ensembl chr 8:118,742,426...118,761,188
|
|
| G
|
Cdc25b
|
cell division cycle 25B
|
decreases expression increases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of CDC25B protein Arsenic Trioxide results in increased expression of CDC25B mRNA
|
CTD |
PMID:10850458 PMID:39716349 |
|
NCBI chr 3:138,860,148...138,870,287
Ensembl chr 3:138,860,130...138,870,492
|
|
| G
|
Cdc25c
|
cell division cycle 25C
|
multiple interactions decreases expression
|
EXP ISO
|
Arsenic Trioxide affects the expression of and affects the phosphorylation of CDC25C protein [Arsenic Trioxide co-treated with Paclitaxel] results in increased expression of CDC25C protein modified form; Arsenic Trioxide promotes the reaction [Docetaxel results in decreased expression of CDC25C mRNA]; Arsenic Trioxide promotes the reaction [Docetaxel results in decreased expression of CDC25C protein]; Arsenic Trioxide promotes the reaction [Oxaliplatin results in decreased expression of CDC25C mRNA]; Arsenic Trioxide promotes the reaction [Oxaliplatin results in decreased expression of CDC25C protein] Arsenic Trioxide results in decreased expression of CDC25C mRNA; Arsenic Trioxide results in decreased expression of CDC25C protein
|
CTD |
PMID:10850458 PMID:19781537 PMID:23337567 PMID:39903385 |
|
NCBI chr18:26,608,483...26,630,292
Ensembl chr18:26,609,959...26,630,292
|
|
| G
|
Cdc27
|
cell division cycle 27
|
multiple interactions
|
ISO
|
[Arsenic Trioxide co-treated with Paclitaxel] results in increased expression of CDC27 protein modified form
|
CTD |
PMID:19781537 |
|
NCBI chr10:89,900,676...89,949,770
Ensembl chr10:89,900,684...89,949,770
|
|
| G
|
Cdc34
|
cell division cycle 34, ubiquitin conjugating enzyme
|
decreases expression increases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of CDC34 mRNA Arsenic Trioxide results in increased expression of CDC34 mRNA
|
CTD |
PMID:17530438 PMID:20458559 |
|
NCBI chr 7:10,668,209...10,674,206
Ensembl chr 7:10,668,210...10,674,526
|
|
| G
|
Cdc37
|
cell division cycle 37, HSP90 cochaperone
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of CDC37 mRNA
|
CTD |
PMID:17530438 |
|
NCBI chr 8:27,954,292...27,966,935
Ensembl chr 8:27,948,016...27,983,931
|
|
| G
|
Cdc42
|
cell division cycle 42
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of CDC42 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 5:154,838,478...154,876,629
Ensembl chr 5:154,839,631...154,876,627
|
|
| G
|
Cdc42bpa
|
CDC42 binding protein kinase alpha
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of CDC42BPA mRNA
|
CTD |
PMID:15761015 PMID:19128835 |
|
NCBI chr13:94,215,359...94,435,681
Ensembl chr13:94,215,959...94,435,681
|
|
| G
|
Cdc42ep3
|
CDC42 effector protein 3
|
multiple interactions
|
ISO
|
[Tretinoin co-treated with Arsenic Trioxide] results in decreased expression of CDC42EP3 mRNA
|
CTD |
PMID:15894607 |
|
NCBI chr 6:21,463,081...21,483,553
Ensembl chr 6:21,461,762...21,508,540
|
|
| G
|
Cdc45
|
cell division cycle 45
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of CDC45 mRNA
|
CTD |
PMID:19128835 PMID:34413873 |
|
NCBI chr11:95,689,702...95,714,980
Ensembl chr11:95,689,919...95,714,981
|
|
| G
|
Cdc6
|
cell division cycle 6
|
increases expression multiple interactions
|
ISO
|
Arsenic Trioxide results in increased expression of CDC6 mRNA; Arsenic Trioxide results in increased expression of CDC6 protein 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Arsenic Trioxide results in increased expression of CDC6 protein]; 9-methoxy-2-methylellipticinium acetate inhibits the reaction [Arsenic Trioxide results in increased expression of CDC6 protein]; AKT1 protein affects the reaction [Arsenic Trioxide results in increased expression of CDC6 protein]; MAPK1 protein affects the reaction [Arsenic Trioxide results in increased expression of CDC6 protein]; MAPK3 protein affects the reaction [Arsenic Trioxide results in increased expression of CDC6 protein]; SB 203580 inhibits the reaction [Arsenic Trioxide results in increased expression of CDC6 protein]
|
CTD |
PMID:20862710 PMID:23255470 |
|
NCBI chr10:84,360,361...84,374,239
Ensembl chr10:84,360,381...84,374,241
|
|
| G
|
Cdc7
|
cell division cycle 7
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of CDC7 mRNA
|
CTD |
PMID:17530438 |
|
NCBI chr14:2,949,538...2,969,656
Ensembl chr14:2,949,539...2,969,656
|
|
| G
|
Cdc73
|
cell division cycle 73
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of CDC73 mRNA
|
CTD |
PMID:15761015 |
|
NCBI chr13:57,897,924...58,000,031
Ensembl chr13:57,883,983...57,999,978
|
|
| G
|
Cdh1
|
cadherin 1
|
increases expression decreases expression multiple interactions decreases methylation
|
ISO
|
Arsenic Trioxide results in increased expression of CDH1 mRNA; Arsenic Trioxide results in increased expression of CDH1 protein Arsenic Trioxide results in decreased expression of CDH1 mRNA; Arsenic Trioxide results in decreased expression of CDH1 protein [Arsenic Trioxide results in decreased methylation of CDH1 promoter] which results in increased expression of CDH1 mRNA; [Arsenic Trioxide results in decreased methylation of CDH1 promoter] which results in increased expression of CDH1 protein; [Curcumin co-treated with Arsenic Trioxide] results in increased expression of CDH1 mRNA; Arsenic Trioxide promotes the reaction [Decitabine results in increased expression of CDH1 mRNA]; Arsenic Trioxide promotes the reaction [Tretinoin results in increased expression of CDH1 mRNA]; Arsenic Trioxide results in increased expression of and affects the localization of CDH1 protein; Decitabine promotes the reaction [Arsenic Trioxide results in increased expression of CDH1 mRNA]; Gemcitabine promotes the reaction [Arsenic Trioxide results in increased expression of CDH1 protein]; GH1 protein promotes the reaction [Arsenic Trioxide results in decreased expression of CDH1 mRNA]; MEG3 protein affects the reaction [Arsenic Trioxide results in increased expression of CDH1 protein]; MIR491 mRNA affects the reaction [Arsenic Trioxide results in increased expression of CDH1 protein]; pervanadate inhibits the reaction [Arsenic Trioxide results in increased expression of CDH1 protein]; PKM protein inhibits the reaction [Arsenic Trioxide results in increased expression of CDH1 mRNA]; PKM protein inhibits the reaction [Arsenic Trioxide results in increased expression of CDH1 protein]; Tretinoin promotes the reaction [Arsenic Trioxide results in increased expression of CDH1 mRNA]
|
CTD |
PMID:16613325 PMID:17512576 PMID:23104537 PMID:23851143 PMID:24680928 PMID:29396848 PMID:29409467 PMID:30093655 PMID:31003765 PMID:33634982 PMID:35487055 PMID:36400307 PMID:36442592 More...
|
|
NCBI chr19:51,402,178...51,471,572
Ensembl chr19:51,402,034...51,471,565
|
|
| G
|
Cdh2
|
cadherin 2
|
increases expression multiple interactions decreases expression
|
ISO
|
Arsenic Trioxide results in increased expression of CDH2 protein Gemcitabine promotes the reaction [Arsenic Trioxide results in decreased expression of CDH2 protein]; MEG3 protein affects the reaction [Arsenic Trioxide results in decreased expression of CDH2 protein]; PKM protein inhibits the reaction [Arsenic Trioxide results in decreased expression of CDH2 mRNA]; PKM protein inhibits the reaction [Arsenic Trioxide results in decreased expression of CDH2 protein] Arsenic Trioxide results in decreased expression of CDH2 mRNA; Arsenic Trioxide results in decreased expression of CDH2 protein
|
CTD |
PMID:29396848 PMID:31003765 PMID:36400307 PMID:36442592 |
|
NCBI chr18:8,051,097...8,265,288
Ensembl chr18:8,051,097...8,265,288
|
|
| G
|
Cdh23
|
cadherin-related 23
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of CDH23 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr20:28,783,124...29,165,624
Ensembl chr20:28,783,564...29,165,332
|
|
| G
|
Cdh5
|
cadherin 5
|
multiple interactions decreases expression
|
ISO EXP
|
Arsenic Trioxide results in increased degradation of and affects the localization of CDH5 protein; calpain inhibitor 2 inhibits the reaction [Arsenic Trioxide results in increased degradation of and affects the localization of CDH5 protein]; Diosgenin inhibits the reaction [Arsenic Trioxide results in decreased expression of CDH5 protein]; NR3C1 promotes the reaction [Diosgenin inhibits the reaction [Arsenic Trioxide results in decreased expression of CDH5 protein]]
|
CTD |
PMID:31274337 PMID:39059093 |
|
NCBI chr19:821,875...860,931
Ensembl chr19:822,464...860,822
|
|
| G
|
Cdh8
|
cadherin 8
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of CDH8 mRNA
|
CTD |
PMID:26705709 |
|
NCBI chr19:5,494,552...5,901,950
Ensembl chr19:5,500,221...5,902,627
|
|
| G
|
Cdhr3
|
cadherin-related family member 3
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of CDHR3 mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr 6:55,369,215...55,429,454
Ensembl chr 6:55,369,851...55,429,458
|
|
| G
|
Cdip1
|
cell death-inducing p53 target 1
|
multiple interactions increases expression
|
ISO
|
Metformin inhibits the reaction [Arsenic Trioxide results in increased expression of CDIP1 mRNA]
|
CTD |
PMID:29095437 |
|
NCBI chr10:11,278,213...11,303,415
Ensembl chr10:11,293,827...11,303,415
|
|
| G
|
Cdk1
|
cyclin-dependent kinase 1
|
multiple interactions decreases expression increases expression affects expression decreases activity
|
EXP ISO
|
Arsenic Trioxide results in increased expression of and results in increased phosphorylation of CDK1 protein Arsenic Trioxide results in decreased expression of CDK1 protein modified form [Arsenic Trioxide co-treated with Paclitaxel] results in increased activity of CDK1 protein; [Arsenic Trioxide co-treated with Paclitaxel] results in increased expression of CDK1 protein modified form; Arsenic Trioxide promotes the reaction [CDK1 protein binds to CDKN1A protein]; Arsenic Trioxide results in decreased expression of and results in increased phosphorylation of CDK1 protein; PTEN protein promotes the reaction [Arsenic Trioxide results in increased phosphorylation of CDK1 protein] Arsenic Trioxide results in increased expression of CDK1 mRNA Arsenic Trioxide affects the expression of CDK1 mRNA Arsenic Trioxide results in decreased activity of CDK1 protein
|
CTD |
PMID:10850458 PMID:18088464 PMID:19781537 PMID:19825857 PMID:20862710 PMID:22730174 PMID:23337567 More...
|
|
NCBI chr20:19,265,252...19,280,456
Ensembl chr20:19,265,289...19,280,455
|
|
| G
|
Cdk10
|
cyclin-dependent kinase 10
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of CDK10 mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr19:68,168,040...68,184,923
Ensembl chr19:68,169,874...68,177,599
|
|
| G
|
Cdk11b
|
cyclin-dependent kinase 11B
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of CDK11B mRNA
|
CTD |
PMID:22521957 |
|
NCBI chr 5:171,495,042...171,521,143
Ensembl chr 5:171,495,776...171,521,145
|
|
| G
|
Cdk2
|
cyclin dependent kinase 2
|
multiple interactions decreases expression
|
ISO
|
[ruxolitinib co-treated with Arsenic Trioxide] results in decreased expression of CDK2 mRNA; Arsenic Trioxide inhibits the reaction [PDGFB protein results in increased expression of CDK2 protein]; Arsenic Trioxide promotes the reaction [CDK2 protein binds to CDKN1A protein]; Arsenic Trioxide results in decreased expression of and results in decreased activity of CDK2 protein Arsenic Trioxide results in decreased expression of CDK2 mRNA
|
CTD |
PMID:12480548 PMID:20458559 PMID:30012499 PMID:35276128 |
|
NCBI chr 7:1,714,392...1,721,964
Ensembl chr 7:1,714,392...1,721,878
|
|
| G
|
Cdk2ap2
|
cyclin-dependent kinase 2 associated protein 2
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of CDK2AP2 mRNA
|
CTD |
PMID:35676786 |
|
NCBI chr 1:210,819,155...210,822,604
Ensembl chr 1:210,820,507...210,823,010
|
|
| G
|
Cdk4
|
cyclin-dependent kinase 4
|
increases expression multiple interactions
|
ISO
|
Arsenic Trioxide results in increased expression of CDK4 mRNA Arsenic Trioxide inhibits the reaction [PDGFB protein results in increased expression of CDK4 protein]
|
CTD |
PMID:17530438 PMID:19769630 PMID:20016248 PMID:35276128 |
|
NCBI chr 7:64,771,453...64,774,891
Ensembl chr 7:64,771,147...64,775,163
|
|
| G
|
Cdk5
|
cyclin-dependent kinase 5
|
increases expression
|
EXP
|
Arsenic Trioxide results in increased expression of CDK5 mRNA; Arsenic Trioxide results in increased expression of CDK5 protein
|
CTD |
PMID:22801079 PMID:24641850 |
|
NCBI chr 4:11,647,098...11,651,606
Ensembl chr 4:11,647,141...11,652,777
|
|
| G
|
Cdk5r1
|
cyclin-dependent kinase 5 regulatory subunit 1
|
increases expression
|
EXP
|
Arsenic Trioxide results in increased expression of CDK5R1 mRNA; Arsenic Trioxide results in increased expression of CDK5R1 protein modified form
|
CTD |
PMID:24641850 |
|
NCBI chr10:65,981,692...65,985,831
Ensembl chr10:65,978,911...65,989,272
|
|
| G
|
Cdk6
|
cyclin-dependent kinase 6
|
multiple interactions decreases expression decreases activity
|
ISO
|
[Arsenic Trioxide results in decreased activity of CDK6 protein] which results in decreased phosphorylation of RB1 protein; [BIBR 1532 co-treated with Arsenic Trioxide] affects the expression of CDK6 mRNA; [Dasatinib co-treated with Arsenic Trioxide] results in decreased expression of CDK6 mRNA; Arsenic Trioxide promotes the reaction [CDK6 protein binds to CDKN1A protein]; Arsenic Trioxide results in decreased expression of and results in decreased activity of CDK6 protein Arsenic Trioxide results in decreased expression of CDK6 mRNA; Arsenic Trioxide results in decreased expression of CDK6 protein
|
CTD |
PMID:10850458 PMID:12480548 PMID:29266867 PMID:32645343 |
|
NCBI chr 4:31,592,384...31,784,732
Ensembl chr 4:31,601,192...31,781,701
|
|
| G
|
Cdkn1a
|
cyclin-dependent kinase inhibitor 1A
|
increases stability increases sumoylation decreases methylation decreases expression increases response to substance increases expression multiple interactions affects expression
|
ISO EXP
|
Arsenic Trioxide results in increased stability of CDKN1A protein Arsenic Trioxide results in increased sumoylation of CDKN1A protein Arsenic Trioxide results in decreased methylation of CDKN1A promoter Arsenic Trioxide results in decreased expression of CDKN1A mRNA CDKN1A protein results in increased susceptibility to Arsenic Trioxide Arsenic Trioxide results in increased expression of CDKN1A mRNA; Arsenic Trioxide results in increased expression of CDKN1A protein 2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [Arsenic Trioxide results in increased expression of CDKN1A protein]; pifithrin inhibits the reaction [Arsenic Trioxide results in increased expression of CDKN1A mRNA] Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased expression of CDKN1A protein]; Arsenic Trioxide promotes the reaction [CDKN1A protein binds to CASP3 protein]; Arsenic Trioxide promotes the reaction [CDKN1A protein binds to PCNA protein] 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt inhibits the reaction [Arsenic Trioxide results in increased expression of CDKN1A mRNA]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Arsenic Trioxide results in increased expression of CDKN1A mRNA]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one promotes the reaction [Arsenic Trioxide results in increased expression of CDKN1A mRNA]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one promotes the reaction [Arsenic Trioxide results in increased expression of CDKN1A protein]; 4-((3-bromophenyl)amino)-6,7-dimethoxyquinazoline inhibits the reaction [Arsenic Trioxide results in increased expression of CDKN1A mRNA]; 4-((3-bromophenyl)amino)-6,7-dimethoxyquinazoline inhibits the reaction [Arsenic Trioxide results in increased expression of CDKN1A protein]; 4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [Arsenic Trioxide results in increased expression of CDKN1A mRNA]; 4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [Arsenic Trioxide results in increased expression of CDKN1A protein]; [[Arsenic Trioxide results in increased phosphorylation of JUN protein] which binds to HDAC1 protein] which binds to CDKN1A promoter; [Arsenic Trioxide co-treated with Aprepitant] results in increased expression of CDKN1A mRNA; [Arsenic Trioxide co-treated with Calcitriol] results in increased expression of CDKN1A mRNA; [Arsenic Trioxide co-treated with Calcitriol] results in increased expression of CDKN1A protein; [Arsenic Trioxide co-treated with Cisplatin] results in increased expression of CDKN1A mRNA; [Arsenic Trioxide co-treated with Curcumin] results in increased expression of CDKN1A protein; [Arsenic Trioxide results in increased phosphorylation of and results in increased activity of FOS protein] promotes the reaction [FOS protein binds to CDKN1A promoter]; [Arsenic Trioxide results in increased phosphorylation of and results in increased activity of FOS protein] promotes the reaction [FOS protein results in increased expression of CDKN1A mRNA]; [Arsenic Trioxide results in increased phosphorylation of and results in increased activity of JUN protein] which results in decreased expression of CDKN1A mRNA; [Arsenic Trioxide results in increased phosphorylation of JUN protein] which results in decreased expression of CDKN1A; [Arsenic Trioxide results in increased phosphorylation of JUN protein] which results in decreased expression of CDKN1A mRNA; [NVP-BKM120 co-treated with Arsenic Trioxide] results in increased expression of CDKN1A mRNA; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased expression of CDKN1A protein]; Arsenic Trioxide inhibits the reaction [Dasatinib results in decreased expression of CDKN1A protein]; Arsenic Trioxide promotes the reaction [[CREBBP protein binds to CDKN1A promoter] which results in increased expression of CDKN1A mRNA]; Arsenic Trioxide promotes the reaction [[FOS protein binds to JUN promoter] which binds to CDKN1A promoter]; Arsenic Trioxide promotes the reaction [[FOS protein binds to JUN protein] which results in increased expression of CDKN1A mRNA]; Arsenic Trioxide promotes the reaction [[JUN protein binds to CDKN1A promoter] which results in increased expression of CDKN1A protein]; Arsenic Trioxide promotes the reaction [[TGIF1 protein co-treated with HDAC1 protein] binds to CDKN1A promoter]; Arsenic Trioxide promotes the reaction [[TGIF1 protein co-treated with HDAC1 protein] results in decreased expression of CDKN1A mRNA]; Arsenic Trioxide promotes the reaction [CCNE1 protein binds to CDKN1A protein]; Arsenic Trioxide promotes the reaction [CDK1 protein binds to CDKN1A protein]; Arsenic Trioxide promotes the reaction [CDK2 protein binds to CDKN1A protein]; Arsenic Trioxide promotes the reaction [CDK6 protein binds to CDKN1A protein]; Arsenic Trioxide promotes the reaction [CREBBP protein binds to CDKN1A promoter]; Arsenic Trioxide promotes the reaction [FOS protein binds to CDKN1A promoter]; Arsenic Trioxide promotes the reaction [MAPK1 protein promotes the reaction [FOS protein binds to CDKN1A promoter]]; Arsenic Trioxide promotes the reaction [MAPK3 protein promotes the reaction [FOS protein binds to CDKN1A promoter]]; Erlotinib Hydrochloride promotes the reaction [Arsenic Trioxide results in increased expression of CDKN1A mRNA]; GSK3B protein modified form affects the reaction [Arsenic Trioxide results in increased expression of CDKN1A protein]; pyrazolanthrone inhibits the reaction [Arsenic Trioxide results in increased expression of CDKN1A protein]; pyrazolanthrone promotes the reaction [Arsenic Trioxide results in increased expression of CDKN1A mRNA]; pyrazolanthrone promotes the reaction [Arsenic Trioxide results in increased expression of CDKN1A protein]; RTKI cpd inhibits the reaction [Arsenic Trioxide results in increased expression of CDKN1A protein]; SMAD3 protein promotes the reaction [Arsenic Trioxide results in increased expression of CDKN1A mRNA]; SMAD3 protein promotes the reaction [Arsenic Trioxide results in increased expression of CDKN1A protein]; TGIF1 protein inhibits the reaction [Arsenic Trioxide results in increased expression of CDKN1A mRNA]; TGIF1 protein inhibits the reaction [Arsenic Trioxide results in increased expression of CDKN1A protein]; U 0126 inhibits the reaction [Arsenic Trioxide results in increased expression of CDKN1A protein] Arsenic Trioxide affects the expression of CDKN1A mRNA; Arsenic Trioxide affects the expression of CDKN1A protein
|
CTD |
PMID:10850458 PMID:12480548 PMID:12749819 PMID:12864950 PMID:15073043 PMID:15723287 PMID:15916724 PMID:15961274 PMID:16283431 PMID:17487067 PMID:18088464 PMID:18210215 PMID:18822310 PMID:19763917 PMID:19951532 PMID:20074581 PMID:20200477 PMID:20458559 PMID:20953137 PMID:21257625 PMID:21278055 PMID:21454520 PMID:21565247 PMID:21649584 PMID:22521957 PMID:22532027 PMID:23337567 PMID:24801890 PMID:25791921 PMID:26705709 PMID:27430728 PMID:28318385 PMID:29159499 PMID:29266867 PMID:29274334 PMID:29944906 PMID:30145367 PMID:31539632 PMID:31734849 PMID:34025784 PMID:34413873 PMID:36442592 PMID:36801614 PMID:38275666 More...
|
|
NCBI chr20:7,150,820...7,161,373
Ensembl chr20:7,153,958...7,164,969
|
|
| G
|
Cdkn1b
|
cyclin-dependent kinase inhibitor 1B
|
decreases expression multiple interactions increases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of CDKN1B mRNA [Arsenic Trioxide co-treated with Calcitriol] results in increased expression of CDKN1B mRNA; [Arsenic Trioxide co-treated with Calcitriol] results in increased expression of CDKN1B protein; [Arsenic Trioxide co-treated with Curcumin] results in increased expression of CDKN1B protein; [Arsenic Trioxide co-treated with VS-5584] results in increased expression of CDKN1B mRNA; [Curcumin co-treated with Arsenic Trioxide] results in increased expression of CDKN1B protein; [NVP-BKM120 co-treated with Arsenic Trioxide] results in increased expression of CDKN1B mRNA; Arsenic Trioxide results in increased expression of and results in increased localization of CDKN1B protein; salvin promotes the reaction [Arsenic Trioxide results in increased expression of CDKN1B protein] Arsenic Trioxide results in increased expression of CDKN1B gene; Arsenic Trioxide results in increased expression of CDKN1B mRNA; Arsenic Trioxide results in increased expression of CDKN1B protein
|
CTD |
PMID:19236751 PMID:19769630 PMID:20458559 PMID:20698225 PMID:20953137 PMID:21257625 PMID:21544632 PMID:23239002 PMID:27430728 PMID:29574283 PMID:31421153 PMID:31539632 PMID:34025784 PMID:36352148 More...
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|
NCBI chr 4:169,491,273...169,496,500
Ensembl chr 4:169,490,876...169,496,498
|
|
| G
|
Cdkn1c
|
cyclin-dependent kinase inhibitor 1C
|
decreases expression increases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of CDKN1C protein Arsenic Trioxide results in increased expression of CDKN1C mRNA
|
CTD |
PMID:34413873 |
|
NCBI chr 1:208,084,801...208,087,680
Ensembl chr 1:208,084,787...208,087,498
|
|
| G
|
Cdkn2a
|
cyclin-dependent kinase inhibitor 2A
|
decreases methylation multiple interactions increases expression
|
ISO EXP
|
Arsenic Trioxide results in decreased methylation of CDKN2A gene; Arsenic Trioxide results in decreased methylation of CDKN2A promoter [Arsenic Trioxide co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of CDKN2A mRNA; [Arsenic Trioxide results in decreased methylation of CDKN2A gene] which results in increased expression of CDKN2A mRNA; [Arsenic Trioxide results in decreased methylation of CDKN2A promoter] which results in increased expression of CDKN2A mRNA; Arsenic Trioxide promotes the reaction [Decitabine results in increased expression of CDKN2A mRNA]; Arsenic Trioxide results in increased expression of and affects the localization of CDKN2A protein; Decitabine promotes the reaction [Arsenic Trioxide results in increased expression of CDKN2A mRNA]; GH1 protein promotes the reaction [Arsenic Trioxide results in increased expression of CDKN2A mRNA]; SB 203580 inhibits the reaction [Arsenic Trioxide results in increased expression of CDKN2A protein] Arsenic Trioxide results in increased expression of CDKN2A gene; Arsenic Trioxide results in increased expression of CDKN2A mRNA; Arsenic Trioxide results in increased expression of CDKN2A protein
|
CTD |
PMID:12864950 PMID:15191659 PMID:16008847 PMID:16613325 PMID:18922899 PMID:19769630 PMID:20416177 PMID:20596618 PMID:21544632 PMID:23851143 PMID:31734849 More...
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|
NCBI chr 5:109,100,763...109,114,448
Ensembl chr 5:109,100,772...109,119,248
|
|
| G
|
Cdkn2b
|
cyclin-dependent kinase inhibitor 2B
|
decreases methylation multiple interactions increases expression
|
ISO
|
Arsenic Trioxide results in decreased methylation of CDKN2B gene [Arsenic Trioxide results in decreased methylation of CDKN2B promoter] which results in increased expression of CDKN2B mRNA; [Valproic Acid co-treated with Arsenic Trioxide] results in increased expression of CDKN2B mRNA Arsenic Trioxide results in increased expression of CDKN2B mRNA
|
CTD |
PMID:11877046 PMID:12667347 PMID:12679007 PMID:12864950 PMID:17294728 PMID:19099629 PMID:20596618 More...
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|
NCBI chr 5:109,123,308...109,134,906
Ensembl chr 5:109,114,322...109,134,855
|
|
| G
|
Cdkn2c
|
cyclin-dependent kinase inhibitor 2C
|
increases expression decreases expression
|
ISO
|
Arsenic Trioxide results in increased expression of CDKN2C mRNA Arsenic Trioxide results in decreased expression of CDKN2C mRNA
|
CTD |
PMID:17530438 PMID:20862710 PMID:26705709 |
|
NCBI chr 5:129,639,736...129,645,564
Ensembl chr 5:129,639,736...129,644,891
|
|
| G
|
Cdkn2d
|
cyclin dependent kinase inhibitor 2D
|
increases expression multiple interactions
|
ISO
|
Arsenic Trioxide results in increased expression of CDKN2D mRNA [Tretinoin co-treated with Arsenic Trioxide] results in increased expression of CDKN2D mRNA
|
CTD |
PMID:15894607 PMID:19769630 PMID:20458559 |
|
NCBI chr 8:28,108,036...28,110,809
Ensembl chr 8:28,108,044...28,110,809
|
|
| G
|
Cdkn3
|
cyclin-dependent kinase inhibitor 3
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of CDKN3 mRNA
|
CTD |
PMID:17547211 PMID:34108876 PMID:34413873 |
|
NCBI chr15:22,502,299...22,513,725
Ensembl chr15:22,502,382...22,513,722
|
|
| G
|
Cdnf
|
cerebral dopamine neurotrophic factor
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to CDNF protein]
|
CTD |
PMID:26598702 |
|
NCBI chr17:79,623,728...79,637,800
Ensembl chr17:79,611,623...79,665,922
|
|
| G
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Cdon
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cell adhesion associated, oncogene regulated
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of CDON mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr 8:42,032,921...42,119,451
Ensembl chr 8:42,033,042...42,119,345
|
|
| G
|
Cdr2
|
cerebellar degeneration-related protein 2
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of CDR2 mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr 1:184,934,128...184,959,036
Ensembl chr 1:184,934,129...184,968,863
|
|
| G
|
Cds1
|
CDP-diacylglycerol synthase 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of CDS1 mRNA
|
CTD |
PMID:29633893 |
|
NCBI chr14:8,126,678...8,187,243
Ensembl chr14:8,124,838...8,187,218
|
|
| G
|
Cdv3
|
carnitine deficiency-associated gene expressed in ventricle 3
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of CDV3 mRNA
|
CTD |
PMID:17258074 |
|
NCBI chr 8:112,812,898...112,826,073
Ensembl chr 8:112,813,952...112,826,056
|
|
| G
|
Cdx1
|
caudal type homeo box 1
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of CDX1 mRNA
|
CTD |
PMID:30748021 |
|
NCBI chr18:56,742,970...56,761,299
Ensembl chr18:56,742,984...56,761,299
|
|
| G
|
Cdx2
|
caudal type homeo box 2
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of CDX2 mRNA
|
CTD |
PMID:30748021 PMID:39716349 |
|
NCBI chr12:12,762,769...12,769,246
Ensembl chr12:12,762,904...12,769,246
|
|
| G
|
Cebpa
|
CCAAT/enhancer binding protein alpha
|
decreases expression increases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of CEBPA mRNA; Arsenic Trioxide results in decreased expression of CEBPA protein Arsenic Trioxide results in increased expression of CEBPA mRNA
|
CTD |
PMID:15916724 PMID:19662097 PMID:20458559 PMID:21257625 |
|
NCBI chr 1:96,896,584...96,899,256
Ensembl chr 1:96,896,171...96,899,309
|
|
| G
|
Cebpb
|
CCAAT/enhancer binding protein beta
|
decreases methylation increases expression multiple interactions decreases expression
|
ISO
|
Arsenic Trioxide results in decreased methylation of CEBPB promoter Arsenic Trioxide results in increased expression of CEBPB mRNA; Arsenic Trioxide results in increased expression of CEBPB protein [Tretinoin co-treated with Arsenic Trioxide] results in increased expression of CEBPB mRNA; Arsenic Trioxide inhibits the reaction [DAXX protein binds to CEBPB protein]; Bortezomib inhibits the reaction [Arsenic Trioxide results in decreased expression of CEBPB mRNA]
|
CTD |
PMID:15894607 PMID:19690170 PMID:20471514 PMID:24356939 PMID:25424538 PMID:26046465 More...
|
|
NCBI chr 3:176,817,005...176,818,436
Ensembl chr 3:176,816,859...176,838,072
|
|
| G
|
Cebpd
|
CCAAT/enhancer binding protein delta
|
increases expression multiple interactions
|
ISO
|
Arsenic Trioxide results in increased expression of CEBPD mRNA [Tretinoin co-treated with Arsenic Trioxide] results in decreased expression of CEBPD mRNA
|
CTD |
PMID:15894607 PMID:26705709 |
|
NCBI chr11:98,268,856...98,269,994
Ensembl chr11:98,265,651...98,280,824
|
|
| G
|
Cebpe
|
CCAAT/enhancer binding protein epsilon
|
multiple interactions
|
ISO
|
[Tretinoin co-treated with Arsenic Trioxide co-treated with Butyrates] results in increased expression of CEBPE mRNA; [Tretinoin co-treated with Arsenic Trioxide co-treated with hexamethylene bisacetamide] results in increased expression of CEBPE mRNA; [Tretinoin co-treated with Arsenic Trioxide] results in increased expression of CEBPE mRNA; Arsenic Trioxide inhibits the reaction [Tretinoin results in increased expression of CEBPE mRNA]
|
CTD |
PMID:12130515 PMID:16184197 |
|
NCBI chr15:32,139,716...32,141,476
Ensembl chr15:32,139,716...32,141,476
|
|
| G
|
Cebpz
|
CCAAT/enhancer binding protein zeta
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of CEBPZ mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 6:21,872,071...21,889,755
Ensembl chr 6:21,872,025...21,889,749
|
|
| G
|
Cela1
|
chymotrypsin like elastase 1
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to CELA1 protein]
|
CTD |
PMID:26598702 |
|
NCBI chr 7:133,651,939...133,665,136
Ensembl chr 7:133,651,941...133,665,061
|
|
| G
|
Cela2a
|
chymotrypsin like elastase 2A
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of CELA2A mRNA
|
CTD |
PMID:15761015 |
|
NCBI chr 5:159,409,900...159,420,282
Ensembl chr 5:159,409,899...159,426,208
|
|
| G
|
Celsr1
|
cadherin, EGF LAG seven-pass G-type receptor 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of CELSR1 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 7:118,867,450...119,004,859
Ensembl chr 7:118,867,450...119,004,856
|
|
| G
|
Cenpc
|
centromere protein C
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of CENPC mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr14:22,342,910...22,401,522
Ensembl chr14:22,342,927...22,438,590
|
|
| G
|
Cenpp
|
centromere protein P
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to CENPP protein]
|
CTD |
PMID:26598702 |
|
NCBI chr17:15,220,521...15,395,741
Ensembl chr17:15,220,291...15,395,739
|
|
| G
|
Cep112
|
centrosomal protein 112
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of CEP112 mRNA
|
CTD |
PMID:35676786 PMID:39716349 |
|
NCBI chr10:93,865,630...94,332,679
Ensembl chr10:93,865,699...94,332,680
|
|
| G
|
Cep295nl
|
CEP295 N-terminal like
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of CEP295NL mRNA
|
CTD |
PMID:36801614 |
|
NCBI chr10:104,066,652...104,079,787
Ensembl chr10:104,054,640...104,084,291
|
|
| G
|
Cep350
|
centrosomal protein 350
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of CEP350 mRNA
|
CTD |
PMID:35676786 |
|
NCBI chr13:70,573,597...70,714,673
Ensembl chr13:70,573,597...70,714,673
|
|
| G
|
Cep55
|
centrosomal protein 55
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of CEP55 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 1:245,245,272...245,260,835
Ensembl chr 1:245,245,306...245,260,890
|
|
| G
|
Cep57
|
centrosomal protein 57
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of CEP57 mRNA
|
CTD |
PMID:14703492 |
|
NCBI chr 8:18,951,179...18,971,205
Ensembl chr 8:18,932,808...18,970,890
|
|
| G
|
Cep70
|
centrosomal protein 70
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of CEP70 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 8:108,689,562...108,742,620
Ensembl chr 8:108,689,671...108,742,617
|
|
| G
|
Cers4
|
ceramide synthase 4
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of CERS4 mRNA
|
CTD |
PMID:22521957 |
|
NCBI chr12:7,649,610...7,688,066
Ensembl chr12:7,649,610...7,688,070
|
|
| G
|
Ces2e
|
carboxylesterase 2E
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of CES2E mRNA
|
CTD |
PMID:35676786 |
|
NCBI chr19:163,899...179,274
Ensembl chr19:163,859...179,308
|
|
| G
|
Cfap221
|
cilia and flagella associated protein 221
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of CFAP221 mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr13:33,599,322...33,669,721
Ensembl chr13:33,598,895...33,669,549
|
|
| G
|
Cfap36
|
cilia and flagella associated protein 36
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of CFAP36 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr14:107,166,932...107,192,531
Ensembl chr14:107,166,947...107,192,406
|
|
| G
|
Cfap54
|
cilia and flagella associated protein 54
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of CFAP54 mRNA
|
CTD |
PMID:35676786 |
|
NCBI chr 7:29,203,143...29,489,551
Ensembl chr 7:29,202,722...29,491,189
|
|
| G
|
Cfb
|
complement factor B
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of CFB mRNA
|
CTD |
PMID:17547211 |
|
NCBI chr20:3,975,271...3,981,138
Ensembl chr20:3,955,776...3,981,740
|
|
| G
|
Cfd
|
complement factor D
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of CFD mRNA
|
CTD |
PMID:29633893 PMID:35676786 |
|
NCBI chr 7:10,463,773...10,465,496
Ensembl chr 7:10,463,775...10,465,572
|
|
| G
|
Cfdp1
|
craniofacial development protein 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of CFDP1 mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr19:56,627,596...56,733,099
Ensembl chr19:56,626,963...56,733,098
|
|
| G
|
Cfi
|
complement factor I
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of CFI mRNA
|
CTD |
PMID:29633893 |
|
NCBI chr 2:221,062,206...221,104,790
Ensembl chr 2:221,062,212...221,104,786
|
|
| G
|
Cfl1
|
cofilin 1
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of CFL1 protein
|
CTD |
PMID:19364129 |
|
NCBI chr 1:212,227,124...212,230,656
Ensembl chr 1:212,226,121...212,231,353
|
|
| G
|
Cflar
|
CASP8 and FADD-like apoptosis regulator
|
multiple interactions increases expression decreases expression decreases response to substance
|
ISO
|
[Arsenic Trioxide co-treated with TNF protein] results in decreased expression of CFLAR protein; Arsenic Trioxide promotes the reaction [Ethacrynic Acid results in decreased expression of CFLAR protein]; BCL2 inhibits the reaction [[Arsenic Trioxide co-treated with TNF protein] results in decreased expression of CFLAR protein] Arsenic Trioxide results in increased expression of CFLAR mRNA Arsenic Trioxide results in decreased expression of CFLAR mRNA; Arsenic Trioxide results in decreased expression of CFLAR protein; Arsenic Trioxide results in decreased expression of CFLAR protein alternative form CFLAR protein results in decreased susceptibility to Arsenic Trioxide
|
CTD |
PMID:16105982 PMID:16174796 PMID:16434995 PMID:17673311 PMID:22521957 PMID:23082001 More...
|
|
NCBI chr 9:67,679,502...67,747,226
Ensembl chr 9:67,679,559...67,726,434
|
|
| G
|
Cga
|
glycoprotein hormones, alpha polypeptide
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of CGA mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 5:54,283,109...54,295,464
Ensembl chr 5:54,235,019...54,295,464
|
|
| G
|
Cgnl1
|
cingulin-like 1
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of CGNL1 mRNA
|
CTD |
PMID:26705709 |
|
NCBI chr 8:81,154,169...81,305,598
Ensembl chr 8:81,140,091...81,305,747
|
|
| G
|
Chac1
|
ChaC glutathione-specific gamma-glutamylcyclotransferase 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of CHAC1 mRNA
|
CTD |
PMID:23824090 PMID:24356939 PMID:25424538 |
|
NCBI chr 3:126,796,131...126,799,352
Ensembl chr 3:126,796,024...126,799,361
|
|
| G
|
Chad
|
chondroadherin
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of CHAD mRNA
|
CTD |
PMID:35676786 |
|
NCBI chr10:80,009,045...80,012,816
Ensembl chr10:80,008,767...80,012,816
|
|
| G
|
Chchd7
|
coiled-coil-helix-coiled-coil-helix domain containing 7
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of CHCHD7 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 5:21,754,719...21,759,274
Ensembl chr 5:21,754,719...21,759,274
|
|
| G
|
Chd2
|
chromodomain helicase DNA binding protein 2
|
affects methylation increases expression
|
ISO
|
Arsenic Trioxide affects the methylation of CHD2 promoter Arsenic Trioxide results in increased expression of CHD2 mRNA
|
CTD |
PMID:26046465 PMID:39716349 |
|
NCBI chr 1:136,597,993...136,726,874
Ensembl chr 1:136,599,900...136,710,335
|
|
| G
|
Chek1
|
checkpoint kinase 1
|
increases phosphorylation multiple interactions decreases expression
|
ISO EXP
|
Arsenic Trioxide results in increased phosphorylation of CHEK1 protein 2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of CHEK1 protein] Arsenic Trioxide results in decreased expression of CHEK1 mRNA; Arsenic Trioxide results in decreased expression of CHEK1 protein [Arsenic Trioxide co-treated with Oxaliplatin] results in decreased expression of CHEK1 protein; Arsenic Trioxide inhibits the reaction [Oxaliplatin results in increased expression of CHEK1 mRNA]; Arsenic Trioxide promotes the reaction [Docetaxel results in decreased expression of CHEK1 mRNA]; Arsenic Trioxide promotes the reaction [Docetaxel results in decreased expression of CHEK1 protein]
|
CTD |
PMID:16891316 PMID:23337567 PMID:39903385 |
|
NCBI chr 8:44,609,417...44,629,867
Ensembl chr 8:44,609,417...44,629,359
|
|
| G
|
Chek2
|
checkpoint kinase 2
|
increases phosphorylation multiple interactions increases expression
|
EXP ISO
|
Arsenic Trioxide results in increased phosphorylation of CHEK2 protein [ruxolitinib co-treated with Arsenic Trioxide] results in increased phosphorylation of CHEK2 protein; Arsenic Trioxide results in increased phosphorylation of and results in increased activity of CHEK2 protein; PPM1D mutant form promotes the reaction [Arsenic Trioxide results in increased phosphorylation of and results in increased activity of CHEK2 protein] 2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of CHEK2 protein] Arsenic Trioxide results in increased expression of CHEK2 mRNA
|
CTD |
PMID:16891316 PMID:18482988 PMID:22521957 PMID:23337567 PMID:30012499 |
|
NCBI chr12:51,448,838...51,481,159
Ensembl chr12:51,449,140...51,480,667
|
|
| G
|
Chgb
|
chromogranin B
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of CHGB mRNA
|
CTD |
PMID:15761015 |
|
NCBI chr 3:140,496,712...140,510,057
Ensembl chr 3:140,495,951...140,510,054
|
|
| G
|
Chi3l1
|
chitinase 3 like 1
|
multiple interactions increases expression decreases expression
|
ISO
|
[Tretinoin co-treated with Arsenic Trioxide] results in decreased expression of CHI3L1 mRNA Arsenic Trioxide results in increased expression of CHI3L1 mRNA Arsenic Trioxide results in decreased expression of CHI3L1 mRNA
|
CTD |
PMID:15761015 PMID:15894607 PMID:19128835 PMID:35676786 |
|
NCBI chr13:48,193,839...48,201,822
Ensembl chr13:48,193,800...48,201,825
|
|
| G
|
Chia
|
chitinase, acidic
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of CHIA mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 2:196,302,687...196,344,849
Ensembl chr 2:196,302,545...196,344,850
|
|
| G
|
Chit1
|
chitinase 1
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of CHIT1 mRNA
|
CTD |
PMID:19128835 |
|
NCBI chr13:48,117,886...48,165,645
Ensembl chr13:48,145,893...48,165,639
|
|
| G
|
Chka
|
choline kinase alpha
|
increases expression decreases expression
|
ISO
|
Arsenic Trioxide results in increased expression of CHKA mRNA Arsenic Trioxide results in decreased expression of CHKA mRNA
|
CTD |
PMID:20458559 PMID:39716349 |
|
NCBI chr 1:210,506,069...210,554,753
Ensembl chr 1:210,506,056...210,554,752
|
|
| G
|
Chml
|
CHM like Rab escort protein
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of CHML mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr13:90,141,880...90,152,097
Ensembl chr13:90,131,514...90,151,265
|
|
| G
|
Chmp1a
|
charged multivesicular body protein 1A
|
decreases response to substance
|
ISO
|
CHMP1A protein results in decreased susceptibility to Arsenic Trioxide
|
CTD |
PMID:20707922 |
|
NCBI chr19:68,146,672...68,154,952
Ensembl chr19:68,146,672...68,154,952
|
|
| G
|
Chodl
|
chondrolectin
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of CHODL mRNA
|
CTD |
PMID:26705709 |
|
NCBI chr11:31,141,030...31,163,342
Ensembl chr11:31,141,021...31,163,334
|
|
| G
|
Chordc1
|
cysteine and histidine rich domain containing 1
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to CHORDC1 protein]
|
CTD |
PMID:26598702 |
|
NCBI chr 8:23,650,721...23,674,786
Ensembl chr 8:23,650,865...23,677,696
|
|
| G
|
Chrdl1
|
chordin-like 1
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of CHRDL1 mRNA
|
CTD |
PMID:26705709 PMID:35676786 |
|
NCBI chr X:111,685,864...111,789,684
Ensembl chr X:111,685,866...111,789,661
|
|
| G
|
Chrm3
|
cholinergic receptor, muscarinic 3
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of CHRM3 mRNA
|
CTD |
PMID:26705709 |
|
NCBI chr17:64,696,549...65,158,622
Ensembl chr17:64,696,066...65,173,304
|
|
| G
|
Chrna6
|
cholinergic receptor nicotinic alpha 6 subunit
|
decreases expression increases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of CHRNA6 mRNA Arsenic Trioxide results in increased expression of CHRNA6 mRNA
|
CTD |
PMID:20458559 PMID:27829220 |
|
NCBI chr16:71,400,615...71,407,315
Ensembl chr16:71,400,615...71,407,315
|
|
| G
|
Chrna7
|
cholinergic receptor nicotinic alpha 7 subunit
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of CHRNA7 mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr 1:126,123,425...126,249,181
Ensembl chr 1:126,123,425...126,446,858
|
|
| G
|
Chst1
|
carbohydrate sulfotransferase 1
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of CHST1 mRNA
|
CTD |
PMID:26705709 |
|
NCBI chr 3:99,003,987...99,030,214
Ensembl chr 3:99,009,958...99,031,262
|
|
| G
|
Chst6
|
carbohydrate sulfotransferase 6
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of CHST6 mRNA
|
CTD |
PMID:15070760 PMID:15761015 |
|
NCBI chr19:56,769,991...56,790,276
Ensembl chr19:56,769,967...56,790,306
|
|
| G
|
Chtf18
|
chromosome transmission fidelity factor 18
|
increases sumoylation
|
ISO
|
Arsenic Trioxide results in increased sumoylation of CHTF18 protein
|
CTD |
PMID:28318385 |
|
NCBI chr10:15,247,525...15,255,573
Ensembl chr10:15,246,362...15,255,685
|
|
| G
|
Chtop
|
chromatin target of PRMT1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of CHTOP mRNA
|
CTD |
PMID:25258189 |
|
NCBI chr 2:178,278,848...178,291,142
Ensembl chr 2:178,278,848...178,290,348
|
|
| G
|
Chuk
|
component of inhibitor of nuclear factor kappa B kinase complex
|
decreases expression multiple interactions
|
ISO
|
Arsenic Trioxide results in decreased expression of CHUK protein [Arsenic Trioxide results in increased phosphorylation of and results in increased activity of CHUK protein] which results in increased phosphorylation of and results in increased ubiquitination of and results in increased degradation of CCND1 protein; Arsenic Trioxide inhibits the reaction [Homoharringtonine results in increased phosphorylation of CHUK protein]; Arsenic Trioxide results in increased phosphorylation of and results in increased activity of CHUK protein
|
CTD |
PMID:22384180 PMID:23949314 PMID:31307525 |
|
NCBI chr 1:252,908,748...252,944,273
Ensembl chr 1:252,908,749...252,944,273
|
|
| G
|
Ciao1
|
cytosolic iron-sulfur assembly component 1
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of CIAO1 protein
|
CTD |
PMID:30093655 |
|
NCBI chr 3:134,913,639...134,919,244
Ensembl chr 3:134,913,172...134,979,255
|
|
| G
|
Cib1
|
calcium and integrin binding 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of CIB1 mRNA
|
CTD |
PMID:22521957 |
|
NCBI chr 1:143,587,591...143,593,153
Ensembl chr 1:143,587,021...143,593,326
|
|
| G
|
Cidea
|
cell death-inducing DFFA-like effector a
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of CIDEA mRNA
|
CTD |
PMID:17530438 |
|
NCBI chr18:63,164,817...63,190,384
Ensembl chr18:63,164,099...63,190,382
|
|
| G
|
Cideb
|
cell death-inducing DFFA-like effector b
|
increases expression decreases expression
|
ISO
|
Arsenic Trioxide results in increased expression of CIDEB mRNA Arsenic Trioxide results in decreased expression of CIDEB mRNA
|
CTD |
PMID:17530438 PMID:17547211 |
|
NCBI chr15:33,222,135...33,226,407
Ensembl chr15:33,221,824...33,226,688
|
|
| G
|
Ciita
|
class II, major histocompatibility complex, transactivator
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of CIITA mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr10:5,646,854...5,694,393
Ensembl chr10:5,647,085...5,694,342
|
|
| G
|
Cilk1
|
ciliogenesis associated kinase 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of CILK1 mRNA
|
CTD |
PMID:27829220 |
|
NCBI chr 8:87,868,294...87,922,995
Ensembl chr 8:87,868,156...87,922,995
|
|
| G
|
Cilp2
|
cartilage intermediate layer protein 2
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of CILP2 mRNA
|
CTD |
PMID:35676786 |
|
NCBI chr16:19,573,821...19,581,100
Ensembl chr16:19,573,908...19,581,100
|
|
| G
|
Cited2
|
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of CITED2 mRNA
|
CTD |
PMID:15725085 |
|
NCBI chr 1:14,132,303...14,134,746
Ensembl chr 1:14,103,457...14,134,782
|
|
| G
|
Ckap2
|
cytoskeleton associated protein 2
|
increases expression multiple interactions
|
ISO
|
Arsenic Trioxide results in increased expression of CKAP2 mRNA Metformin inhibits the reaction [Arsenic Trioxide results in increased expression of CKAP2 mRNA]
|
CTD |
PMID:29095437 |
|
NCBI chr16:76,542,114...76,567,297
Ensembl chr16:76,542,104...76,567,352
|
|
| G
|
Ckap4
|
cytoskeleton-associated protein 4
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of CKAP4 mRNA
|
CTD |
PMID:12852829 |
|
NCBI chr 7:21,118,527...21,126,624
Ensembl chr 7:21,118,085...21,126,624
|
|
| G
|
Ckb
|
creatine kinase B
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of CKB protein
|
CTD |
PMID:30093655 |
|
NCBI chr 6:136,550,583...136,553,464
Ensembl chr 6:136,549,844...136,553,478
|
|
| G
|
Ckm
|
creatine kinase, M-type
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of CKM mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 1:88,189,382...88,199,717
Ensembl chr 1:88,189,485...88,199,719
|
|
| G
|
Clca2
|
chloride channel accessory 2
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of CLCA2 mRNA
|
CTD |
PMID:26705709 |
|
NCBI chr 2:236,655,419...236,682,669
Ensembl chr 2:236,639,545...236,685,129
|
|
| G
|
Clcc1
|
chloride channel CLIC-like 1
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of CLCC1 mRNA
|
CTD |
PMID:21461292 |
|
NCBI chr 2:198,984,455...199,015,015
Ensembl chr 2:198,984,495...199,015,014
|
|
| G
|
Clcf1
|
cardiotrophin-like cytokine factor 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of CLCF1 mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr 1:210,937,763...210,947,064
Ensembl chr 1:210,937,255...210,947,064
|
|
| G
|
Cldn1
|
claudin 1
|
multiple interactions increases expression decreases expression
|
ISO
|
Acetylcysteine inhibits the reaction [Arsenic Trioxide results in decreased expression of CLDN1 protein] Arsenic Trioxide results in increased expression of CLDN1 mRNA [Arsenic Trioxide results in increased abundance of arsenite] which results in decreased expression of CLDN1 mRNA
|
CTD |
PMID:26705709 PMID:28115242 PMID:36791901 |
|
NCBI chr11:87,926,376...87,941,533
Ensembl chr11:87,926,337...87,941,529
|
|
| G
|
Cldn11
|
claudin 11
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of CLDN11 mRNA
|
CTD |
PMID:22521957 |
|
NCBI chr 2:114,136,234...114,149,539
Ensembl chr 2:114,136,234...114,149,539
|
|
| G
|
Cldn14
|
claudin 14
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of CLDN14 mRNA
|
CTD |
PMID:19128835 |
|
NCBI chr11:46,701,940...46,799,049
Ensembl chr11:46,701,940...46,799,096
|
|
| G
|
Cldn2
|
claudin 2
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of CLDN2 mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr X:108,248,383...108,258,847
Ensembl chr X:108,237,676...108,262,377
|
|
| G
|
Cldn4
|
claudin 4
|
decreases response to substance
|
ISO
|
CLDN4 protein results in decreased susceptibility to Arsenic Trioxide
|
CTD |
PMID:20707922 |
|
NCBI chr12:27,388,160...27,389,958
Ensembl chr12:27,387,981...27,389,958
|
|
| G
|
Cldn5
|
claudin 5
|
decreases expression multiple interactions
|
ISO
|
Arsenic Trioxide results in decreased expression of CLDN5 mRNA Acetylcysteine inhibits the reaction [Arsenic Trioxide results in decreased expression of CLDN5 protein]
|
CTD |
PMID:28115242 PMID:30032600 PMID:30225639 |
|
NCBI chr11:95,717,172...95,718,598
Ensembl chr11:95,717,176...95,719,322
|
|
| G
|
Cldn7
|
claudin 7
|
decreases response to substance
|
ISO
|
CLDN7 protein results in decreased susceptibility to Arsenic Trioxide
|
CTD |
PMID:20707922 |
|
NCBI chr10:55,188,670...55,190,871
Ensembl chr10:55,188,684...55,190,905
|
|
| G
|
Cldn9
|
claudin 9
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of CLDN9 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr10:13,218,728...13,220,159
Ensembl chr10:13,218,729...13,220,178
|
|
| G
|
Clec11a
|
C-type lectin domain containing 11A
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of CLEC11A mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 1:103,938,029...103,941,170
Ensembl chr 1:103,935,185...103,946,784
|
|
| G
|
Clec2d
|
C-type lectin domain family 2, member D
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of CLEC2D mRNA
|
CTD |
PMID:22521957 |
|
NCBI chr 4:163,902,124...163,925,587
Ensembl chr 4:163,902,547...163,925,587
|
|
| G
|
Clec3a
|
C-type lectin domain family 3, member A
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of CLEC3A mRNA
|
CTD |
PMID:35676786 |
|
NCBI chr19:59,313,746...59,321,126
Ensembl chr19:59,313,570...59,321,126
|
|
| G
|
Clec7a
|
C-type lectin domain containing 7A
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of CLEC7A mRNA
|
CTD |
PMID:15725085 |
|
NCBI chr 4:164,588,737...164,599,953
Ensembl chr 4:164,588,754...164,599,919
|
|
| G
|
Clgn
|
calmegin
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of CLGN mRNA
|
CTD |
PMID:17547211 |
|
NCBI chr19:41,601,568...41,633,207
Ensembl chr19:41,601,568...41,633,325
|
|
| G
|
Clic2
|
chloride intracellular channel 2
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of CLIC2 mRNA
|
CTD |
PMID:26705709 PMID:27829220 |
|
NCBI chr20:154,630...169,655
Ensembl chr20:154,255...169,648
|
|
| G
|
Clic3
|
chloride intracellular channel 3
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to CLIC3 protein]
|
CTD |
PMID:26598702 |
|
NCBI chr 3:28,670,176...28,672,166
Ensembl chr 3:28,670,229...28,675,723
|
|
| G
|
Clic4
|
chloride intracellular channel 4
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of CLIC4 mRNA; Arsenic Trioxide results in increased expression of CLIC4 protein
|
CTD |
PMID:17258074 PMID:30093655 |
|
NCBI chr 5:152,737,371...152,797,118
Ensembl chr 5:152,737,371...152,797,118
|
|
| G
|
Clip4
|
CAP-GLY domain containing linker protein family, member 4
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of CLIP4 mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr 6:29,359,628...29,449,365 NCBI chr 6:29,349,245...29,351,890
Ensembl chr 6:29,348,918...29,449,271
|
|
| G
|
Clk1
|
CDC-like kinase 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of CLK1 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 9:67,441,962...67,453,180
Ensembl chr 9:67,441,952...67,451,187
|
|
| G
|
Clk3
|
CDC-like kinase 3
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of CLK3 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 8:67,048,121...67,063,192
Ensembl chr 8:67,048,123...67,062,881
|
|
| G
|
Clk4
|
CDC-like kinase 4
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of CLK4 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr10:36,024,364...36,042,366
Ensembl chr10:36,024,427...36,042,372
|
|
| G
|
Cln3
|
CLN3 lysosomal/endosomal transmembrane protein, battenin
|
decreases response to substance
|
ISO
|
CLN3 protein results in decreased susceptibility to Arsenic Trioxide
|
CTD |
PMID:20707922 |
|
NCBI chr 1:190,586,649...190,600,034
Ensembl chr 1:190,586,650...190,597,929
|
|
| G
|
Clpb
|
ClpB family mitochondrial disaggregase
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of CLPB mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr 1:165,440,705...165,563,514
Ensembl chr 1:165,440,861...165,583,815
|
|
| G
|
Clspn
|
claspin
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of CLSPN mRNA
|
CTD |
PMID:26705709 |
|
NCBI chr 5:144,134,619...144,169,531
Ensembl chr 5:144,134,632...144,169,530
|
|
| G
|
Clstn1
|
calsyntenin 1
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of CLSTN1 mRNA
|
CTD |
PMID:22521957 |
|
NCBI chr 5:165,314,128...165,377,627
Ensembl chr 5:165,314,309...165,377,625
|
|
| G
|
Clstn2
|
calsyntenin 2
|
multiple interactions
|
ISO
|
[Arsenic Trioxide co-treated with Tretinoin] results in decreased expression of CLSTN2 mRNA
|
CTD |
PMID:38179723 |
|
NCBI chr 8:106,899,894...107,516,402
Ensembl chr 8:106,899,894...107,040,053
|
|
| G
|
Clta
|
clathrin, light chain A
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of CLTA mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 5:63,022,046...63,059,223
Ensembl chr 5:63,041,184...63,059,215
|
|
| G
|
Cltb
|
clathrin, light chain B
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of CLTB mRNA
|
CTD |
PMID:17258074 |
|
NCBI chr17:10,006,416...10,024,278
Ensembl chr17:10,006,656...10,024,915
|
|
| G
|
Cltc
|
clathrin heavy chain
|
decreases expression multiple interactions increases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of CLTC mRNA [Arsenic Trioxide co-treated with nilotinib] affects the expression of CLTC mRNA Arsenic Trioxide results in increased expression of CLTC protein
|
CTD |
PMID:20458559 PMID:25419056 PMID:28786057 |
|
NCBI chr10:72,014,984...72,073,308
Ensembl chr10:72,014,986...72,070,691
|
|
| G
|
Clu
|
clusterin
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of CLU mRNA
|
CTD |
PMID:22521957 PMID:27829220 |
|
NCBI chr15:44,336,619...44,375,861
Ensembl chr15:44,359,914...44,375,860
|
|
| G
|
Cmip
|
c-Maf-inducing protein
|
multiple interactions increases expression
|
ISO
|
[Arsenic Trioxide co-treated with Ascorbic Acid] results in increased expression of CMIP mRNA Arsenic Trioxide results in increased expression of CMIP mRNA
|
CTD |
PMID:25555879 |
|
NCBI chr19:62,213,402...62,419,443
Ensembl chr19:62,213,365...62,417,500
|
|
| G
|
Cmklr1
|
chemerin chemokine-like receptor 1
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of CMKLR1 mRNA
|
CTD |
PMID:25258189 |
|
NCBI chr12:48,634,929...48,687,833
Ensembl chr12:48,634,003...48,691,458
|
|
| G
|
Cmss1
|
cms1 ribosomal small subunit homolog
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of CMSS1 mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr11:56,403,620...56,701,751
Ensembl chr11:56,403,499...56,701,755
|
|
| G
|
Cmtm6
|
CKLF-like MARVEL transmembrane domain containing 6
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of CMTM6 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 8:123,301,131...123,319,230
Ensembl chr 8:123,300,918...123,319,230
|
|
| G
|
Cmtm8
|
CKLF-like MARVEL transmembrane domain containing 8
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of CMTM8 mRNA
|
CTD |
PMID:15761015 |
|
NCBI chr 8:123,360,168...123,425,291
Ensembl chr 8:123,360,170...123,425,276
|
|
| G
|
Cnbp
|
CCHC-type zinc finger, nucleic acid binding protein
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of CNBP mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 4:121,860,102...121,868,976
Ensembl chr 4:121,860,105...121,869,010
|
|
| G
|
Cnmd
|
chondromodulin
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of CNMD mRNA
|
CTD |
PMID:18414637 |
|
NCBI chr15:61,450,617...61,475,382
Ensembl chr15:61,450,450...61,475,350
|
|
| G
|
Cnnm2
|
cyclin and CBS domain divalent metal cation transport mediator 2
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of CNNM2 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 1:255,585,063...255,709,455
Ensembl chr 1:255,585,095...255,704,849
|
|
| G
|
Cnnm4
|
cyclin and CBS domain divalent metal cation transport mediator 4
|
multiple interactions decreases response to substance
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to CNNM4 protein] CNNM4 protein results in decreased susceptibility to Arsenic Trioxide
|
CTD |
PMID:20707922 PMID:26598702 |
|
NCBI chr 9:46,207,602...46,246,817
Ensembl chr 9:46,207,551...46,246,817
|
|
| G
|
Cnot2
|
CCR4-NOT transcription complex, subunit 2
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of CNOT2 mRNA
|
CTD |
PMID:15761015 |
|
NCBI chr 7:54,016,447...54,117,511
Ensembl chr 7:54,016,447...54,107,960
|
|
| G
|
Cnot6l
|
CCR4-NOT transcription complex, subunit 6-like
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of CNOT6L mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr14:13,714,475...13,806,481
Ensembl chr14:13,714,475...13,806,481
|
|
| G
|
Cnot9
|
CCR4-NOT transcription complex subunit 9
|
multiple interactions decreases expression
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to CNOT9 protein] Arsenic Trioxide results in decreased expression of CNOT9 protein
|
CTD |
PMID:25419056 PMID:26598702 |
|
NCBI chr 9:83,533,369...83,558,207
Ensembl chr 9:83,533,369...83,558,197
|
|
| G
|
Cntn1
|
contactin 1
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of CNTN1 mRNA
|
CTD |
PMID:26705709 |
|
NCBI chr 7:125,142,638...125,440,397
Ensembl chr 7:125,142,696...125,440,391
|
|
| G
|
Cntn3
|
contactin 3
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of CNTN3 mRNA
|
CTD |
PMID:26705709 |
|
NCBI chr 4:136,397,575...136,770,765
Ensembl chr 4:136,398,572...136,770,717
|
|
| G
|
Cntnap1
|
contactin associated protein 1
|
multiple interactions decreases expression
|
ISO
|
[Arsenic Trioxide co-treated with Ascorbic Acid] results in increased expression of CNTNAP1 mRNA Arsenic Trioxide results in decreased expression of CNTNAP1 mRNA
|
CTD |
PMID:25555879 PMID:27829220 |
|
NCBI chr10:86,610,140...86,625,896
Ensembl chr10:86,611,890...86,631,730
|
|
| G
|
Coa7
|
cytochrome c oxidase assembly factor 7
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of COA7 mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr 5:128,298,084...128,308,935
Ensembl chr 5:128,298,093...128,309,664
|
|
| G
|
Coasy
|
Coenzyme A synthase
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of COASY protein
|
CTD |
PMID:25419056 |
|
NCBI chr10:86,514,850...86,519,130
Ensembl chr10:86,514,874...86,519,130
|
|
| G
|
Cobll1
|
cordon-bleu WH2 repeat protein-like 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of COBLL1 mRNA
|
CTD |
PMID:15761015 |
|
NCBI chr 3:70,161,369...70,324,844
Ensembl chr 3:70,161,372...70,323,460
|
|
| G
|
Cog5
|
component of oligomeric golgi complex 5
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of COG5 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 6:53,969,967...54,267,869
Ensembl chr 6:53,969,979...54,278,973
|
|
| G
|
Col12a1
|
collagen type XII alpha 1 chain
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of COL12A1 mRNA
|
CTD |
PMID:35676786 |
|
NCBI chr 8:89,427,834...89,545,886
Ensembl chr 8:89,427,834...89,545,711
|
|
| G
|
Col14a1
|
collagen type XIV alpha 1 chain
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of COL14A1 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 7:88,611,827...88,826,939
Ensembl chr 7:88,611,828...88,826,938
|
|
| G
|
Col16a1
|
collagen type XVI alpha 1 chain
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of COL16A1 mRNA
|
CTD |
PMID:20458559 PMID:35676786 PMID:39716349 |
|
NCBI chr 5:147,672,559...147,727,007
Ensembl chr 5:147,672,601...147,727,011
|
|
| G
|
Col1a1
|
collagen type I alpha 1 chain
|
multiple interactions increases expression decreases expression
|
ISO EXP
|
Arsenic Trioxide inhibits the reaction [Bleomycin results in increased expression of COL1A1 mRNA]; Arsenic Trioxide inhibits the reaction [Bleomycin results in increased expression of COL1A1 protein] Arsenic Trioxide results in increased expression of COL1A1 protein Arsenic Trioxide inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA]; Arsenic Trioxide inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 protein] Arsenic Trioxide results in decreased expression of COL1A1 mRNA Arsenic Trioxide results in increased expression of COL1A1 mRNA Diosgenin inhibits the reaction [Arsenic Trioxide results in increased expression of COL1A1 mRNA]
|
CTD |
PMID:19364129 PMID:24762191 PMID:30317545 PMID:35276128 PMID:39059093 |
|
NCBI chr10:80,380,458...80,397,461
Ensembl chr10:80,380,453...80,397,460
|
|
| G
|
Col1a2
|
collagen type I alpha 2 chain
|
decreases expression multiple interactions
|
ISO
|
Arsenic Trioxide results in decreased expression of COL1A2 mRNA [Arsenic Trioxide co-treated with Ascorbic Acid] results in increased expression of COL1A2 mRNA; [Tetradecanoylphorbol Acetate co-treated with Arsenic Trioxide] results in increased expression of COL1A2 mRNA
|
CTD |
PMID:18922899 PMID:20458559 PMID:25555879 |
|
NCBI chr 4:33,518,557...33,553,484
Ensembl chr 4:33,518,420...33,553,995
|
|
| G
|
Col3a1
|
collagen type III alpha 1 chain
|
increases expression multiple interactions
|
EXP
|
Arsenic Trioxide results in increased expression of COL3A1 mRNA Diosgenin inhibits the reaction [Arsenic Trioxide results in increased expression of COL3A1 mRNA]
|
CTD |
PMID:39059093 |
|
NCBI chr 9:54,866,646...54,902,578
Ensembl chr 9:54,866,632...54,903,232
|
|
| G
|
Col6a3
|
collagen type VI alpha 3 chain
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of COL6A3 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 9:98,809,171...98,887,060
Ensembl chr 9:98,809,171...98,886,990
|
|
| G
|
Col7a1
|
collagen type VII alpha 1 chain
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of COL7A1 mRNA
|
CTD |
PMID:22521957 |
|
NCBI chr 8:118,483,364...118,515,736
Ensembl chr 8:118,483,364...118,517,439
|
|
| G
|
Col8a2
|
collagen type VIII alpha 2 chain
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of COL8A2 mRNA
|
CTD |
PMID:19128835 PMID:26705709 |
|
NCBI chr 5:143,870,754...143,897,372
Ensembl chr 5:143,870,742...143,897,884
|
|
| G
|
Colec10
|
collectin subfamily member 10
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of COLEC10 mRNA
|
CTD |
PMID:15761015 |
|
NCBI chr 7:87,634,686...87,695,465
Ensembl chr 7:87,634,654...87,699,534
|
|
| G
|
Commd3
|
COMM domain containing 3
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of COMMD3 mRNA
|
CTD |
PMID:35676786 |
|
NCBI chr17:86,235,863...86,239,610
Ensembl chr17:86,235,863...86,239,610
|
|
| G
|
Commd6
|
COMM domain containing 6
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of COMMD6 mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr15:84,882,069...84,889,124
Ensembl chr15:84,882,548...84,889,194
|
|
| G
|
Comp
|
cartilage oligomeric matrix protein
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of COMP mRNA
|
CTD |
PMID:35676786 |
|
NCBI chr16:19,081,172...19,089,548
Ensembl chr16:19,081,172...19,089,605
|
|
| G
|
Comt
|
catechol-O-methyltransferase
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of COMT mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr11:96,072,371...96,091,956
Ensembl chr11:96,072,489...96,092,533
|
|
| G
|
Copb1
|
COPI coat complex subunit beta 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of COPB1 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 1:177,838,751...177,876,688
Ensembl chr 1:177,838,752...177,872,840
|
|
| G
|
Copb2
|
COPI coat complex subunit beta 2
|
increases expression decreases expression
|
ISO
|
Arsenic Trioxide results in increased expression of COPB2 protein Arsenic Trioxide results in decreased expression of COPB2 mRNA
|
CTD |
PMID:25419056 PMID:39716349 |
|
NCBI chr 8:108,040,687...108,062,810
Ensembl chr 8:108,040,693...108,064,550
|
|
| G
|
Cops5
|
COP9 signalosome subunit 5
|
multiple interactions
|
ISO
|
[Arsenic Trioxide co-treated with IFNA2 protein co-treated with Docosahexaenoic Acids co-treated with Emodin] results in decreased expression of COPS5 protein; Arsenic Trioxide results in decreased expression of and results in increased localization of COPS5 protein
|
CTD |
PMID:17077332 PMID:20698225 |
|
NCBI chr 5:13,975,198...13,993,391
Ensembl chr 5:13,975,052...13,993,387
|
|
| G
|
Cops6
|
COP9 signalosome subunit 6
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of COPS6 protein
|
CTD |
PMID:25419056 |
|
NCBI chr12:22,152,688...22,155,527
Ensembl chr12:22,147,482...22,161,106
|
|
| G
|
Coq2
|
coenzyme Q2, polyprenyltransferase
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of COQ2 mRNA
|
CTD |
PMID:27829220 |
|
NCBI chr14:9,245,777...9,265,784
Ensembl chr14:9,245,803...9,265,783
|
|
| G
|
Corin
|
corin, serine peptidase
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of CORIN mRNA
|
CTD |
PMID:26705709 |
|
NCBI chr14:36,034,613...36,264,671
Ensembl chr14:36,034,993...36,264,649
|
|
| G
|
Coro1a
|
coronin 1A
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of CORO1A protein
|
CTD |
PMID:19364129 |
|
NCBI chr 1:190,726,129...190,731,133
Ensembl chr 1:190,726,130...190,731,102
|
|
| G
|
Coro2a
|
coronin 2A
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of CORO2A mRNA
|
CTD |
PMID:26705709 |
|
NCBI chr 5:65,623,820...65,677,483
Ensembl chr 5:65,623,823...65,654,602
|
|
| G
|
Coro6
|
coronin 6
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to CORO6 protein]
|
CTD |
PMID:26598702 |
|
NCBI chr10:62,808,172...62,817,788
Ensembl chr10:62,809,689...62,817,787
|
|
| G
|
Cotl1
|
coactosin-like F-actin binding protein 1
|
multiple interactions
|
ISO
|
[Tretinoin co-treated with Arsenic Trioxide] results in increased expression of COTL1 mRNA
|
CTD |
PMID:15894607 |
|
NCBI chr19:64,780,309...64,814,629
Ensembl chr19:64,780,322...64,814,840
|
|
| G
|
Cox10
|
cytochrome c oxidase assembly factor heme A:farnesyltransferase COX10
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of COX10 mRNA
|
CTD |
PMID:22521957 PMID:35676786 |
|
NCBI chr10:49,130,209...49,242,009
Ensembl chr10:49,130,209...49,242,009
|
|
| G
|
Cox11
|
cytochrome c oxidase copper chaperone COX11
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of COX11 mRNA
|
CTD |
PMID:22521957 |
|
NCBI chr10:75,955,825...75,962,398
Ensembl chr10:75,955,783...75,963,489
|
|
| G
|
Cox15
|
cytochrome c oxidase assembly homolog COX15
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of COX15 mRNA
|
CTD |
PMID:22521957 |
|
NCBI chr 1:252,554,811...252,571,471
Ensembl chr 1:252,554,811...252,571,471
|
|
| G
|
Cox17
|
cytochrome c oxidase copper chaperone COX17
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of COX17 mRNA
|
CTD |
PMID:19422848 |
|
NCBI chr11:75,906,245...75,912,036
Ensembl chr11:75,906,248...75,912,019
|
|
| G
|
Cox4i1
|
cytochrome c oxidase subunit 4i1
|
increases expression decreases expression multiple interactions
|
ISO
|
Arsenic Trioxide results in increased expression of COX4I1 mRNA Arsenic Trioxide results in decreased expression of COX4I1 protein 3-(2,4-dichloro-5-methoxyphenyl)-2-sulfanyl-4(3H)-quinazolinone inhibits the reaction [Arsenic Trioxide results in decreased expression of COX4I1 protein]; Cyclosporine inhibits the reaction [Arsenic Trioxide results in decreased expression of COX4I1 protein]
|
CTD |
PMID:20458559 PMID:27318970 |
|
NCBI chr19:65,630,383...65,636,623
Ensembl chr19:65,630,432...65,636,624
|
|
| G
|
Cox5a
|
cytochrome c oxidase subunit 5A
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of COX5A mRNA
|
CTD |
PMID:22521957 |
|
NCBI chr 8:66,818,284...66,829,691
Ensembl chr 8:66,818,196...66,830,279
|
|
| G
|
Cox6a2
|
cytochrome c oxidase subunit 6A2
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of COX6A2 mRNA
|
CTD |
PMID:19422848 |
|
NCBI chr 1:192,218,970...192,221,188
Ensembl chr 1:192,218,970...192,219,716
|
|
| G
|
Cox6b2
|
cytochrome c oxidase subunit 6B2
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to COX6B2 protein]
|
CTD |
PMID:26598702 |
|
NCBI chr 1:78,122,871...78,124,096
Ensembl chr 1:78,122,453...78,124,094
|
|
| G
|
Cox6c
|
cytochrome c oxidase subunit 6C
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of COX6C mRNA
|
CTD |
PMID:25258189 |
|
NCBI chr 7:69,014,410...69,027,145
Ensembl chr 7:69,014,417...69,027,166
|
|
| G
|
Cox7a2l
|
cytochrome c oxidase subunit 7A2 like
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of COX7A2L mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr 6:16,936,574...16,950,797
Ensembl chr 6:16,936,795...16,950,798
|
|
| G
|
Cox7b
|
cytochrome c oxidase subunit 7B
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of COX7B mRNA
|
CTD |
PMID:25258189 |
|
NCBI chr X:75,149,036...75,155,285
Ensembl chr X:75,148,996...75,155,284
|
|
| G
|
Cp
|
ceruloplasmin
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of CP mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 2:104,368,336...104,427,119
Ensembl chr 2:104,368,456...104,427,087
|
|
| G
|
Cpe
|
carboxypeptidase E
|
increases expression decreases expression
|
ISO
|
Arsenic Trioxide results in increased expression of CPE mRNA Arsenic Trioxide results in decreased expression of CPE mRNA
|
CTD |
PMID:19128835 PMID:22535156 |
|
NCBI chr16:29,796,707...29,908,647
Ensembl chr16:29,796,689...29,909,524
|
|
| G
|
Cpeb1
|
cytoplasmic polyadenylation element binding protein 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of CPEB1 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 1:144,709,278...144,817,388
Ensembl chr 1:144,709,691...144,815,880
|
|
| G
|
Cped1
|
cadherin-like and PC-esterase domain containing 1
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of CPED1 mRNA
|
CTD |
PMID:35676786 |
|
NCBI chr 4:51,482,497...51,755,440
Ensembl chr 4:51,482,545...51,755,442
|
|
| G
|
Cpne1
|
copine 1
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to CPNE1 protein]
|
CTD |
PMID:26598702 |
|
NCBI chr 3:165,047,615...165,089,994
|
|
| G
|
Cpne6
|
copine 6
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to CPNE6 protein]
|
CTD |
PMID:26598702 |
|
NCBI chr15:32,968,047...32,975,008
Ensembl chr15:32,968,046...32,975,007
|
|
| G
|
Cpne7
|
copine 7
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of CPNE7 mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr19:68,072,165...68,091,197
Ensembl chr19:68,074,545...68,091,197
|
|
| G
|
Cpt1a
|
carnitine palmitoyltransferase 1A
|
decreases expression increases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of CPT1A mRNA Arsenic Trioxide results in increased expression of CPT1A mRNA
|
CTD |
PMID:22521957 PMID:30237538 |
|
NCBI chr 1:209,993,881...210,056,329
Ensembl chr 1:209,993,875...210,056,326
|
|
| G
|
Cpt1b
|
carnitine palmitoyltransferase 1B
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of CPT1B mRNA
|
CTD |
PMID:22521957 |
|
NCBI chr 7:122,370,974...122,380,473
Ensembl chr 7:122,370,444...122,380,036
|
|
| G
|
Cptp
|
ceramide-1-phosphate transfer protein
|
multiple interactions increases expression
|
ISO
|
Metformin inhibits the reaction [Arsenic Trioxide results in increased expression of CPTP mRNA]
|
CTD |
PMID:29095437 |
|
NCBI chr 5:171,757,181...171,761,271
Ensembl chr 5:171,757,181...171,761,266
|
|
| G
|
Cpxm2
|
carboxypeptidase X (M14 family), member 2
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of CPXM2 mRNA
|
CTD |
PMID:35676786 |
|
NCBI chr 1:196,266,930...196,377,350
Ensembl chr 1:196,266,930...196,377,347
|
|
| G
|
Crabp1
|
cellular retinoic acid binding protein 1
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to CRABP1 protein]
|
CTD |
PMID:26598702 |
|
NCBI chr 8:64,047,431...64,055,469
Ensembl chr 8:64,047,060...64,055,470
|
|
| G
|
Cracr2a
|
calcium release activated channel regulator 2A
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of CRACR2A mRNA
|
CTD |
PMID:25258189 |
|
NCBI chr 4:162,094,247...162,207,926
Ensembl chr 4:162,110,929...162,221,529
|
|
| G
|
Crat
|
carnitine O-acetyltransferase
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of CRAT mRNA
|
CTD |
PMID:34108876 |
|
NCBI chr 3:34,073,504...34,087,099
Ensembl chr 3:34,073,506...34,087,099
|
|
| G
|
Crbn
|
cereblon
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to CRBN protein]
|
CTD |
PMID:26598702 |
|
NCBI chr 4:141,255,400...141,276,722
Ensembl chr 4:141,257,243...141,276,038
|
|
| G
|
Creb1
|
cAMP responsive element binding protein 1
|
decreases expression increases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of CREB1 mRNA Arsenic Trioxide results in increased expression of CREB1 mRNA
|
CTD |
PMID:24831965 PMID:39716349 |
|
NCBI chr 9:73,397,333...73,466,339
Ensembl chr 9:73,397,306...73,466,339
|
|
| G
|
Creb3l2
|
cAMP responsive element binding protein 3-like 2
|
multiple interactions increases expression
|
ISO
|
Metformin inhibits the reaction [Arsenic Trioxide results in increased expression of CREB3L2 mRNA]
|
CTD |
PMID:29095437 |
|
NCBI chr 4:66,874,623...66,990,962
Ensembl chr 4:66,387,126...66,990,832
|
|
| G
|
Creb5
|
cAMP responsive element binding protein 5
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of CREB5 mRNA
|
CTD |
PMID:15761015 |
|
NCBI chr 4:83,723,587...84,124,786
Ensembl chr 4:83,723,194...84,120,793
|
|
| G
|
Crebbp
|
CREB binding protein
|
multiple interactions decreases expression
|
ISO
|
Arsenic Trioxide promotes the reaction [[CREBBP protein binds to CDKN1A promoter] which results in increased expression of CDKN1A mRNA]; Arsenic Trioxide promotes the reaction [CREBBP protein binds to CDKN1A promoter]; Arsenic Trioxide promotes the reaction [CREBBP protein results in increased expression of VCP mRNA] Arsenic Trioxide results in decreased expression of CREBBP mRNA
|
CTD |
PMID:18822310 PMID:24831965 |
|
NCBI chr10:11,842,307...11,968,266
Ensembl chr10:11,822,620...11,968,266
|
|
| G
|
Crem
|
cAMP responsive element modulator
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of CREM mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr17:58,932,011...59,001,160
Ensembl chr17:58,934,147...59,001,160
|
|
| G
|
Crh
|
corticotropin releasing hormone
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of CRH mRNA
|
CTD |
PMID:15761015 |
|
NCBI chr 2:104,059,184...104,061,048
Ensembl chr 2:104,058,770...104,061,386
|
|
| G
|
Crim1
|
cysteine rich transmembrane BMP regulator 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of CRIM1 mRNA
|
CTD |
PMID:15725085 PMID:15761015 PMID:24356939 PMID:25424538 |
|
NCBI chr 6:22,447,983...22,622,459
Ensembl chr 6:22,449,948...22,622,416
|
|
| G
|
Crip1
|
cysteine rich protein 1
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to CRIP1 protein]
|
CTD |
PMID:26598702 |
|
NCBI chr 6:138,047,801...138,055,672
Ensembl chr 6:138,047,801...138,055,672
|
|
| G
|
Crkl
|
CRK like proto-oncogene, adaptor protein
|
multiple interactions
|
ISO
|
[nilotinib co-treated with Arsenic Trioxide] results in decreased phosphorylation of CRKL protein
|
CTD |
PMID:23883479 |
|
NCBI chr11:97,033,033...97,067,457
Ensembl chr11:97,024,782...97,067,457
|
|
| G
|
Crlf3
|
cytokine receptor-like factor 3
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to CRLF3 protein]
|
CTD |
PMID:26598702 |
|
NCBI chr10:65,521,296...65,559,162
Ensembl chr10:65,521,492...65,558,804
|
|
| G
|
Crls1
|
cardiolipin synthase 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of CRLS1 mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr 3:140,572,680...140,591,543
Ensembl chr 3:140,572,716...140,591,599
|
|
| G
|
Crp
|
C-reactive protein
|
increases expression
|
EXP
|
Arsenic Trioxide results in increased expression of CRP
|
CTD |
PMID:21851829 |
|
NCBI chr13:87,694,062...87,695,978
Ensembl chr13:87,657,317...87,707,514
|
|
| G
|
Cry2
|
cryptochrome circadian regulator 2
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of CRY2 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 3:98,830,479...98,860,437
Ensembl chr 3:98,830,483...98,860,447
|
|
| G
|
Cryab
|
crystallin, alpha B
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of CRYAB mRNA
|
CTD |
PMID:25258189 |
|
NCBI chr 8:59,989,885...59,995,532
Ensembl chr 8:59,989,814...59,995,528
|
|
| G
|
Crygn
|
crystallin, gamma N
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to CRYGN protein]
|
CTD |
PMID:26598702 |
|
NCBI chr 4:11,286,475...11,294,002
Ensembl chr 4:11,286,475...11,294,002
|
|
| G
|
Cryzl2
|
crystallin zeta like 2
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of CRYZL2P mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr13:72,146,147...72,210,258
Ensembl chr13:72,144,307...72,188,560
|
|
| G
|
Csf1
|
colony stimulating factor 1
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [CSF1 protein results in increased expression of TGM2 mRNA]; Arsenic Trioxide inhibits the reaction [CSF1 protein results in increased expression of TGM2 protein]
|
CTD |
PMID:37446117 |
|
NCBI chr 2:198,065,400...198,084,774
Ensembl chr 2:198,065,405...198,084,468
|
|
| G
|
Csf1r
|
colony stimulating factor 1 receptor
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of CSF1R gene mutant form
|
CTD |
PMID:38746032 |
|
NCBI chr18:56,834,152...56,860,804
Ensembl chr18:56,817,049...56,860,806
|
|
| G
|
Csf2
|
colony stimulating factor 2
|
increases expression decreases expression multiple interactions
|
EXP ISO
|
Arsenic Trioxide results in increased expression of CSF2 mRNA Arsenic Trioxide results in decreased expression of CSF2 mRNA; Arsenic Trioxide results in decreased expression of CSF2 protein [Arsenic Trioxide co-treated with CSF2] results in decreased activity of RELA protein; [CSF2 protein co-treated with Arsenic Trioxide] affects the activity of CASP3 protein; [CSF2 protein co-treated with Arsenic Trioxide] results in decreased expression of and affects the activity of CASP8 protein; [CSF2 protein co-treated with Arsenic Trioxide] results in decreased expression of and results in increased cleavage of CASP3 protein
|
CTD |
PMID:16174796 PMID:22465848 PMID:29049341 |
|
NCBI chr10:38,887,692...38,889,673
Ensembl chr10:38,887,692...38,890,031
|
|
| G
|
Csf2rb
|
colony stimulating factor 2 receptor subunit beta
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of CSF2RB mRNA
|
CTD |
PMID:15070760 |
|
NCBI chr 7:111,756,950...111,782,089
Ensembl chr 7:111,757,405...111,784,654
|
|
| G
|
Csf3
|
colony stimulating factor 3
|
multiple interactions increases expression increases response to substance increases uptake
|
ISO
|
[CSF3 protein results in increased expression of AQP9 mRNA] which results in increased uptake of Arsenic Trioxide; [CSF3 protein results in increased expression of AQP9 protein] which results in increased uptake of Arsenic Trioxide; AQP9 protein promotes the reaction [CSF3 protein results in increased uptake of Arsenic Trioxide]; CSF3 protein inhibits the reaction [Tretinoin results in decreased uptake of Arsenic Trioxide] Arsenic Trioxide results in increased expression of CSF3 protein CSF3 protein results in increased susceptibility to Arsenic Trioxide
|
CTD |
PMID:22940758 PMID:35590355 PMID:37166470 |
|
NCBI chr10:84,157,485...84,159,860
Ensembl chr10:84,157,211...84,159,860
|
|
| G
|
Csgalnact1
|
chondroitin sulfate N-acetylgalactosaminyltransferase 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of CSGALNACT1 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr16:25,761,946...26,097,306
Ensembl chr16:26,002,530...26,096,065
|
|
| G
|
Csnk1d
|
casein kinase 1, delta
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of CSNK1D mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr10:106,713,497...106,754,953
Ensembl chr10:106,694,279...106,754,953
|
|
| G
|
Cspg5
|
chondroitin sulfate proteoglycan 5
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of CSPG5 mRNA
|
CTD |
PMID:26705709 |
|
NCBI chr 8:119,098,932...119,113,191
Ensembl chr 8:119,098,925...119,143,907
|
|
| G
|
Cspp1
|
centrosome and spindle pole associated protein 1
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of CSPP1 mRNA
|
CTD |
PMID:15761015 PMID:22521957 |
|
NCBI chr 5:13,860,072...13,975,299
Ensembl chr 5:13,860,072...13,975,321
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| G
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Csrp1
|
cysteine and glycine-rich protein 1
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of CSRP1 mRNA
|
CTD |
PMID:21461292 |
|
NCBI chr13:49,709,928...49,731,141
Ensembl chr13:49,709,914...49,731,139
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| G
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Csrp2
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cysteine and glycine-rich protein 2
|
increases expression decreases expression
|
ISO
|
Arsenic Trioxide results in increased expression of CSRP2 mRNA Arsenic Trioxide results in decreased expression of CSRP2 mRNA
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CTD |
PMID:19128835 PMID:25258189 |
|
NCBI chr 7:48,235,415...48,254,049
Ensembl chr 7:48,235,383...48,266,238
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| G
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Csrp3
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cysteine and glycine rich protein 3
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decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of CSRP3 mRNA
|
CTD |
PMID:15725085 |
|
NCBI chr 1:107,664,338...107,682,916
Ensembl chr 1:107,664,338...107,682,916
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| G
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Cst3
|
cystatin C
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decreases expression increases expression multiple interactions
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ISO EXP
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Arsenic Trioxide results in decreased expression of CST3 mRNA Arsenic Trioxide results in increased expression of CST3 protein Febuxostat inhibits the reaction [Arsenic Trioxide results in increased expression of CST3 protein]
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CTD |
PMID:15725085 PMID:37689273 |
|
NCBI chr 3:156,790,061...156,794,116
Ensembl chr 3:156,790,079...156,793,937
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| G
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Csta
|
cystatin A
|
increases expression affects expression
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ISO
|
Arsenic Trioxide results in increased expression of CSTA mRNA Arsenic Trioxide affects the expression of CSTA mRNA
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CTD |
PMID:20458559 PMID:24356939 PMID:26705709 PMID:27825931 |
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NCBI chr11:78,125,813...78,136,818
Ensembl chr11:78,125,800...78,136,822
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| G
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Cstb
|
cystatin B
|
increases expression decreases expression
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ISO
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Arsenic Trioxide results in increased expression of CSTB protein Arsenic Trioxide results in decreased expression of CSTB protein
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CTD |
PMID:19364129 PMID:30093655 |
|
NCBI chr20:10,245,157...10,247,199
Ensembl chr20:10,245,158...10,247,199
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| G
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Cstf2
|
cleavage stimulation factor subunit 2
|
increases expression
|
ISO
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Arsenic Trioxide results in increased expression of CSTF2 protein
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CTD |
PMID:15894607 |
|
NCBI chr X:101,546,809...101,572,760
Ensembl chr X:101,546,819...101,572,764
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| G
|
Cstl1
|
cystatin-like 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of CSTL1 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 3:156,652,967...156,658,049
Ensembl chr 3:156,653,052...156,658,049
|
|
| G
|
Ctbp1
|
C-terminal binding protein 1
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to CTBP1 protein]
|
CTD |
PMID:26598702 |
|
NCBI chr14:81,679,956...81,707,331
Ensembl chr14:81,679,765...81,707,554
|
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| G
|
Ctbp2
|
C-terminal binding protein 2
|
decreases response to substance
|
ISO
|
CTBP2 protein results in decreased susceptibility to Arsenic Trioxide
|
CTD |
PMID:20707922 |
|
NCBI chr 1:197,208,536...197,348,802
Ensembl chr 1:197,212,133...197,254,261
|
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| G
|
Ctcf
|
CCCTC-binding factor
|
affects methylation
|
ISO
|
Arsenic Trioxide affects the methylation of CTCF promoter
|
CTD |
PMID:26046465 |
|
NCBI chr19:50,431,478...50,481,013
Ensembl chr19:50,431,689...50,481,012
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|
| G
|
Ctdsp1
|
CTD small phosphatase 1
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of CTDSP1 mRNA
|
CTD |
PMID:26705709 |
|
NCBI chr 9:83,422,755...83,428,411
Ensembl chr 9:83,423,051...83,428,412
|
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| G
|
Ctdspl2
|
CTD small phosphatase like 2
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of CTDSPL2 mRNA
|
CTD |
PMID:35676786 |
|
NCBI chr 3:129,365,709...129,424,232
Ensembl chr 3:129,368,938...129,424,232
|
|
| G
|
Ctf1
|
cardiotrophin 1
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to CTF1 protein]
|
CTD |
PMID:26598702 |
|
NCBI chr 1:191,758,512...191,771,259
Ensembl chr 1:191,757,477...191,776,395
|
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| G
|
Cth
|
cystathionine gamma-lyase
|
increases expression multiple interactions
|
ISO
|
Arsenic Trioxide results in increased expression of CTH mRNA Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to CTH protein]
|
CTD |
PMID:19417148 PMID:26598702 PMID:26705709 |
|
NCBI chr 2:249,634,731...249,661,066
Ensembl chr 2:249,634,731...249,661,066
|
|
| G
|
Ctla4
|
cytotoxic T-lymphocyte-associated protein 4
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of CTLA4 mRNA
|
CTD |
PMID:34108876 |
|
NCBI chr 9:69,812,859...69,819,959
Ensembl chr 9:69,813,265...69,819,973
|
|
| G
|
Ctnna1
|
catenin alpha 1
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of CTNNA1 mRNA
|
CTD |
PMID:15761015 |
|
NCBI chr18:27,002,330...27,135,009
Ensembl chr18:26,999,820...27,135,007
|
|
| G
|
Ctnna2
|
catenin alpha 2
|
multiple interactions
|
ISO
|
[Arsenic Trioxide co-treated with apatinib] results in increased expression of CTNNA2 mRNA
|
CTD |
PMID:39223679 |
|
NCBI chr 4:110,852,265...112,001,351
Ensembl chr 4:110,852,265...112,001,365
|
|
| G
|
Ctnnal1
|
catenin alpha-like 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of CTNNAL1 mRNA
|
CTD |
PMID:22521957 |
|
NCBI chr 5:76,309,546...76,375,869
Ensembl chr 5:76,309,546...76,364,637
|
|
| G
|
Ctnnb1
|
catenin beta 1
|
decreases expression increases expression multiple interactions increases cleavage affects expression
|
ISO
|
Arsenic Trioxide results in decreased expression of CTNNB1 mRNA; Arsenic Trioxide results in decreased expression of CTNNB1 protein Arsenic Trioxide results in increased expression of CTNNB1 mRNA [Arsenic Trioxide binds to PIN1 protein] affects the reaction [Arsenic Trioxide results in decreased expression of CTNNB1 protein]; [Arsenic Trioxide co-treated with apatinib] results in decreased expression of CTNNB1 protein; Arsenic Trioxide inhibits the reaction [CTNNB1 protein results in decreased susceptibility to Bortezomib]; Arsenic Trioxide inhibits the reaction [Lithium Chloride results in increased expression of CTNNB1 protein]; Arsenic Trioxide promotes the reaction [Tretinoin results in decreased expression of CTNNB1 protein]; CAB39L protein alternative form inhibits the reaction [Arsenic Trioxide results in decreased expression of CTNNB1 mRNA]; CAB39L protein alternative form inhibits the reaction [Arsenic Trioxide results in decreased expression of CTNNB1 protein]; GRB10 protein promotes the reaction [[Arsenic Trioxide co-treated with apatinib] results in decreased expression of CTNNB1 protein]; ICG 001 affects the reaction [RORB protein affects the reaction [Arsenic Trioxide affects the expression of CTNNB1 protein]]; N-(4-methoxybenzyl)-N'-(5-nitro-1,3-thiazol-2-yl)urea inhibits the reaction [Arsenic Trioxide results in decreased expression of CTNNB1 protein]; PIN1 protein affects the reaction [Arsenic Trioxide results in decreased expression of CTNNB1 protein]; RORB protein affects the reaction [Arsenic Trioxide affects the expression of CTNNB1 protein]; Tretinoin promotes the reaction [Arsenic Trioxide results in decreased expression of CTNNB1 protein] Arsenic Trioxide results in increased cleavage of CTNNB1 protein
|
CTD |
PMID:12181429 PMID:17512576 PMID:18485479 PMID:20458559 PMID:26966376 PMID:28565807 PMID:28901456 PMID:29059232 PMID:30093655 PMID:32305283 PMID:38797699 PMID:39223679 More...
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|
NCBI chr 8:129,517,576...129,544,661
Ensembl chr 8:129,517,545...129,544,662
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| G
|
Ctnnd1
|
catenin delta 1
|
decreases response to substance increases expression
|
ISO
|
CTNND1 protein results in decreased susceptibility to Arsenic Trioxide Arsenic Trioxide results in increased expression of CTNND1 mRNA
|
CTD |
PMID:20707922 PMID:35676786 |
|
NCBI chr 3:90,090,025...90,141,247
Ensembl chr 3:90,090,564...90,141,189
|
|
| G
|
Ctps1
|
CTP synthase 1
|
multiple interactions
|
ISO
|
[Tretinoin co-treated with Arsenic Trioxide] results in increased expression of CTPS1 mRNA
|
CTD |
PMID:15894607 |
|
NCBI chr 5:139,372,349...139,440,441
Ensembl chr 5:139,410,249...139,440,465
|
|
| G
|
Ctps2
|
CTP synthase 2
|
decreases expression multiple interactions
|
ISO
|
Arsenic Trioxide results in decreased expression of CTPS2 mRNA [Arsenic Trioxide co-treated with Ascorbic Acid] results in decreased expression of CTPS2 mRNA
|
CTD |
PMID:25555879 |
|
NCBI chr X:35,277,658...35,418,505
Ensembl chr X:35,277,658...35,418,505
|
|
| G
|
Ctsa
|
cathepsin A
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of CTSA mRNA
|
CTD |
PMID:15725085 PMID:20458559 |
|
NCBI chr 3:173,988,443...173,994,320
Ensembl chr 3:173,988,460...173,995,539
|
|
| G
|
Ctsb
|
cathepsin B
|
increases expression increases activity multiple interactions decreases activity decreases expression
|
ISO
|
Arsenic Trioxide results in increased expression of CTSB mRNA Arsenic Trioxide results in increased activity of CTSB protein 3-methyladenine inhibits the reaction [[Arsenic Trioxide co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of CTSB protein]; [Arsenic Trioxide co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of CTSB protein; [Arsenic Trioxide co-treated with Silybin] results in decreased expression of CTSB mRNA; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased expression of CTSB mRNA]; Arsenic Trioxide promotes the reaction [CTSB protein results in increased degradation of BCR protein mutant form]; CA 074 methyl ester inhibits the reaction [[Arsenic Trioxide co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of CTSB protein]; Chloroquine inhibits the reaction [Arsenic Trioxide results in increased activity of CTSB protein]; Taurine inhibits the reaction [[Arsenic Trioxide co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of CTSB protein]; TFEB protein affects the reaction [Arsenic Trioxide results in increased expression of CTSB mRNA] Taurine inhibits the reaction [Arsenic Trioxide results in increased expression of CTSB protein] Arsenic Trioxide results in decreased activity of CTSB protein Arsenic Trioxide results in decreased expression of CTSB mRNA
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CTD |
PMID:21969006 PMID:22898604 PMID:27039805 PMID:27829220 PMID:29307831 PMID:30237538 PMID:30338810 More...
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|
NCBI chr15:41,565,607...41,586,479
Ensembl chr15:41,565,611...41,586,478
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| G
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Ctsc
|
cathepsin C
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of CTSC mRNA
|
CTD |
PMID:26705709 |
|
NCBI chr 1:151,440,860...151,472,430
Ensembl chr 1:151,441,032...151,474,082
|
|
| G
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Ctsd
|
cathepsin D
|
increases expression multiple interactions
|
ISO
|
Arsenic Trioxide results in increased expression of CTSD protein Arsenic Trioxide promotes the reaction [AG 1879 results in increased expression of CTSD protein]
|
CTD |
PMID:23864846 PMID:25419056 |
|
NCBI chr 1:206,956,945...206,968,821
Ensembl chr 1:206,956,944...206,968,821
|
|
| G
|
Ctsg
|
cathepsin G
|
multiple interactions
|
ISO
|
[Tretinoin co-treated with Arsenic Trioxide] results in decreased expression of CTSG mRNA
|
CTD |
PMID:15894607 |
|
NCBI chr15:33,901,230...33,907,596
Ensembl chr15:33,901,754...33,907,596
|
|
| G
|
Ctsh
|
cathepsin H
|
multiple interactions decreases expression
|
ISO
|
[Tretinoin co-treated with Arsenic Trioxide] results in decreased expression of CTSH mRNA Arsenic Trioxide results in decreased expression of CTSH mRNA
|
CTD |
PMID:15761015 PMID:15894607 PMID:39716349 |
|
NCBI chr 8:99,488,756...99,507,639
Ensembl chr 8:99,488,874...99,509,181
|
|
| G
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Ctsl
|
cathepsin L
|
multiple interactions
|
ISO
|
[CTSL protein affects the susceptibility to [Arsenic Trioxide results in increased abundance of arsenite]] which affects the expression of TP53 protein; Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to CTSL protein]; CTSL protein affects the susceptibility to [Arsenic Trioxide results in increased abundance of arsenite]
|
CTD |
PMID:23968587 PMID:26598702 |
|
NCBI chr17:770,104...776,266
Ensembl chr17:770,093...777,113
|
|
| G
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Ctso
|
cathepsin O
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of CTSO mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr 2:169,528,468...169,551,975
Ensembl chr 2:169,528,511...169,554,995
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|
| G
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Ctss
|
cathepsin S
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of CTSS mRNA
|
CTD |
PMID:19101991 |
|
NCBI chr 2:185,775,316...185,803,440
Ensembl chr 2:185,775,296...185,803,440
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|
| G
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Cttn
|
cortactin
|
multiple interactions
|
ISO
|
[Tretinoin co-treated with Arsenic Trioxide] results in increased expression of CTTN mRNA
|
CTD |
PMID:15894607 |
|
NCBI chr 1:209,029,048...209,064,577
Ensembl chr 1:209,029,048...209,058,211
|
|
| G
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Cttnbp2nl
|
CTTNBP2 N-terminal like
|
multiple interactions decreases expression
|
ISO
|
Metformin inhibits the reaction [Arsenic Trioxide results in decreased expression of CTTNBP2NL mRNA]
|
CTD |
PMID:29095437 |
|
NCBI chr 2:195,196,318...195,244,792
Ensembl chr 2:195,196,318...195,243,181
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|
| G
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Cul1
|
cullin 1
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of CUL1 mRNA
|
CTD |
PMID:29633893 |
|
NCBI chr 4:77,551,781...77,634,210
Ensembl chr 4:77,551,787...77,621,760
|
|
| G
|
Cul2
|
cullin 2
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of CUL2 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr17:58,864,274...58,905,447
Ensembl chr17:58,864,274...58,905,132
|
|
| G
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Cul5
|
cullin 5
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of CUL5 mRNA
|
CTD |
PMID:17530438 |
|
NCBI chr 8:62,909,150...62,974,641
Ensembl chr 8:62,912,193...62,965,463
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|
| G
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Cwf19l1
|
CWF19 like cell cycle control factor 1
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of CWF19L1 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 1:252,946,934...252,970,194
Ensembl chr 1:252,946,934...252,970,168
|
|
| G
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Cx3cl1
|
C-X3-C motif chemokine ligand 1
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of CX3CL1 mRNA
|
CTD |
PMID:17547211 |
|
NCBI chr19:10,233,326...10,244,856
Ensembl chr19:10,233,329...10,242,999
|
|
| G
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Cxcl10
|
C-X-C motif chemokine ligand 10
|
increases expression decreases expression
|
ISO
|
Arsenic Trioxide results in increased expression of CXCL10 mRNA Arsenic Trioxide results in decreased expression of CXCL10 mRNA
|
CTD |
PMID:17530438 PMID:27829220 PMID:38684648 |
|
NCBI chr14:15,989,066...15,991,263
Ensembl chr14:15,989,018...15,991,261
|
|
| G
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Cxcl11
|
C-X-C motif chemokine ligand 11
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of CXCL11 mRNA
|
CTD |
PMID:38684648 |
|
NCBI chr14:15,973,728...15,976,503
Ensembl chr14:15,973,720...15,976,567
|
|
| G
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Cxcl12
|
C-X-C motif chemokine ligand 12
|
multiple interactions increases expression
|
ISO
|
Arsenic Trioxide inhibits the reaction [CXCL12 protein results in increased expression of CXCR4 protein]; Arsenic Trioxide inhibits the reaction [CXCL12 protein results in increased phosphorylation of and results in increased degradation of NFKBIA protein]; RELA protein inhibits the reaction [Arsenic Trioxide inhibits the reaction [CXCL12 protein results in increased expression of CXCR4 protein]] Arsenic Trioxide results in increased expression of CXCL12 mRNA
|
CTD |
PMID:25047463 PMID:38684648 |
|
NCBI chr 4:152,060,781...152,073,628
Ensembl chr 4:152,060,780...152,073,627
|
|
| G
|
Cxcl14
|
C-X-C motif chemokine ligand 14
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of CXCL14 mRNA
|
CTD |
PMID:26705709 |
|
NCBI chr17:8,323,150...8,331,176
Ensembl chr17:8,323,143...8,331,172
|
|
| G
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Cxcl16
|
C-X-C motif chemokine ligand 16
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of CXCL16 mRNA
|
CTD |
PMID:25258189 |
|
NCBI chr10:55,665,355...55,669,950
Ensembl chr10:55,664,742...55,670,226
|
|
| G
|
Cxcl2
|
C-X-C motif chemokine ligand 2
|
multiple interactions increases expression
|
ISO
|
Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased expression of CXCL2 mRNA]
|
CTD |
PMID:19128835 PMID:19350554 |
|
NCBI chr14:17,465,210...17,467,255
Ensembl chr14:17,465,242...17,467,255
|
|
| G
|
Cxcl3
|
C-X-C motif chemokine ligand 3
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of CXCL1 mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr14:17,571,900...17,573,624
Ensembl chr14:17,571,900...17,573,624
|
|
| G
|
Cxcl9
|
C-X-C motif chemokine ligand 9
|
decreases expression increases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of CXCL9 mRNA Arsenic Trioxide results in increased expression of CXCL9 mRNA
|
CTD |
PMID:18414637 PMID:38684648 |
|
NCBI chr14:16,007,166...16,012,077
Ensembl chr14:16,007,204...16,014,299
|
|
| G
|
Cxcr2
|
C-X-C motif chemokine receptor 2
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of CXCR2 mRNA
|
CTD |
PMID:15761015 |
|
NCBI chr 9:83,178,645...83,185,017
Ensembl chr 9:83,183,808...83,188,602
|
|
| G
|
Cxcr3
|
C-X-C motif chemokine receptor 3
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of CXCR3 mRNA
|
CTD |
PMID:34108876 |
|
NCBI chr X:70,884,293...70,886,944
Ensembl chr X:70,883,958...70,886,871
|
|
| G
|
Cxcr4
|
C-X-C motif chemokine receptor 4
|
multiple interactions decreases expression affects expression
|
ISO
|
Arsenic Trioxide inhibits the reaction [CXCL12 protein results in increased expression of CXCR4 protein]; Arsenic Trioxide inhibits the reaction [Oxygen deficiency results in increased expression of CXCR4 mRNA]; Arsenic Trioxide inhibits the reaction [Oxygen deficiency results in increased expression of CXCR4 protein]; PPP2CA protein affects the reaction [Arsenic Trioxide results in decreased expression of CXCR4 protein]; RELA protein inhibits the reaction [Arsenic Trioxide inhibits the reaction [CXCL12 protein results in increased expression of CXCR4 protein]]; RELA protein inhibits the reaction [Arsenic Trioxide results in decreased expression of CXCR4 protein] Arsenic Trioxide results in decreased expression of CXCR4 mRNA; Arsenic Trioxide results in decreased expression of CXCR4 protein Arsenic Trioxide affects the expression of CXCR4 mRNA
|
CTD |
PMID:20458559 PMID:25047463 PMID:26705709 |
|
NCBI chr13:42,630,383...42,634,288
Ensembl chr13:42,630,104...42,634,459
|
|
| G
|
Cxxc5
|
CXXC finger protein 5
|
multiple interactions
|
ISO
|
[Tretinoin co-treated with Arsenic Trioxide] results in increased expression of CXXC5 mRNA
|
CTD |
PMID:15894607 |
|
NCBI chr18:27,701,650...27,732,633
Ensembl chr18:27,701,188...27,732,635
|
|
| G
|
Cyb561d1
|
cytochrome b561 family, member D1
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of CYB561D1 mRNA
|
CTD |
PMID:35676786 |
|
NCBI chr 2:198,523,031...198,525,671
Ensembl chr 2:198,523,031...198,525,676
|
|
| G
|
Cyb5r2
|
cytochrome b5 reductase 2
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of CYB5R2 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 1:171,062,083...171,076,183
Ensembl chr 1:171,067,614...171,075,904
|
|
| G
|
Cyb5r3
|
cytochrome b5 reductase 3
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of CYB5R3 mRNA
|
CTD |
PMID:15725085 |
|
NCBI chr 7:116,186,729...116,204,290
Ensembl chr 7:116,186,729...116,204,306
|
|
| G
|
Cyba
|
cytochrome b-245 alpha chain
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of CYBA mRNA
|
CTD |
PMID:15070760 PMID:27750169 |
|
NCBI chr19:67,396,143...67,404,214
Ensembl chr19:67,396,143...67,404,214
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| G
|
Cybb
|
cytochrome b-245 beta chain
|
decreases expression multiple interactions
|
ISO
|
Arsenic Trioxide results in decreased expression of CYBB mRNA [Tretinoin co-treated with Arsenic Trioxide] results in increased expression of CYBB mRNA
|
CTD |
PMID:15894607 PMID:20458559 PMID:28454374 |
|
NCBI chr X:16,030,596...16,065,065
Ensembl chr X:16,030,596...16,065,065
|
|
| G
|
Cybrd1
|
cytochrome b reductase 1
|
increases expression decreases expression
|
ISO
|
Arsenic Trioxide results in increased expression of CYBRD1 mRNA Arsenic Trioxide results in decreased expression of CYBRD1 mRNA
|
CTD |
PMID:15761015 PMID:39716349 |
|
NCBI chr 3:76,342,231...76,369,846
Ensembl chr 3:76,342,404...76,370,061
|
|
| G
|
Cyc1
|
cytochrome c-1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of CYC1 mRNA
|
CTD |
PMID:22521957 |
|
NCBI chr 7:109,947,750...109,950,142
Ensembl chr 7:109,947,766...109,950,657
|
|
| G
|
Cycs
|
cytochrome c, somatic
|
affects localization multiple interactions increases expression increases secretion
|
EXP ISO
|
Arsenic Trioxide affects the localization of CYCS protein Acetylcysteine inhibits the reaction [Arsenic Trioxide affects the localization of CYCS protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide promotes the reaction [CASP9 protein binds to CYCS protein]]; Arsenic Trioxide promotes the reaction [CYCS protein binds to CASP9 protein]; salvianolic acid A inhibits the reaction [Arsenic Trioxide affects the localization of CYCS protein]; trans-sodium crocetinate inhibits the reaction [Arsenic Trioxide results in increased expression of CYCS protein] Arsenic Trioxide results in increased expression of and affects the localization of CYCS protein; ATF4 protein promotes the reaction [Arsenic Trioxide results in increased expression of and affects the localization of CYCS protein] [Arsenic Trioxide co-treated with Curcumin] results in increased expression of CYCS protein; [Arsenic Trioxide co-treated with esculetin] affects the localization of CYCS protein; pyrazolanthrone promotes the reaction [Arsenic Trioxide affects the localization of CYCS protein]; U 0126 promotes the reaction [Arsenic Trioxide affects the localization of CYCS protein] Arsenic Trioxide results in increased expression of CYCS mRNA; Arsenic Trioxide results in increased expression of CYCS protein Arsenic Trioxide results in increased secretion of CYCS protein
|
CTD |
PMID:15979664 PMID:16972261 PMID:19428345 PMID:21145380 PMID:22521957 PMID:24634002 PMID:27430728 PMID:27638049 PMID:28391263 PMID:32919218 PMID:38275666 More...
|
|
NCBI chr 4:80,982,667...80,984,767
Ensembl chr 4:80,982,668...80,984,816 Ensembl chr18:80,982,668...80,984,816
|
|
| G
|
Cyfip2
|
cytoplasmic FMR1 interacting protein 2
|
multiple interactions
|
ISO
|
[Tretinoin co-treated with Arsenic Trioxide] results in increased expression of CYFIP2 mRNA
|
CTD |
PMID:15894607 |
|
NCBI chr10:31,122,653...31,242,440
Ensembl chr10:31,122,653...31,242,440
|
|
| G
|
Cygb
|
cytoglobin
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to CYGB protein]
|
CTD |
PMID:26598702 |
|
NCBI chr10:102,376,506...102,386,272
Ensembl chr10:102,376,507...102,386,272
|
|
| G
|
Cyld
|
CYLD lysine 63 deubiquitinase
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of CYLD mRNA
|
CTD |
PMID:15761015 |
|
NCBI chr19:34,487,491...34,547,311
Ensembl chr19:34,488,583...34,547,118
|
|
| G
|
Cyp11a1
|
cytochrome P450, family 11, subfamily a, polypeptide 1
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of CYP11A1 mRNA
|
CTD |
PMID:18630931 |
|
NCBI chr 8:67,318,665...67,330,196
Ensembl chr 8:67,270,556...67,330,196
|
|
| G
|
Cyp17a1
|
cytochrome P450, family 17, subfamily a, polypeptide 1
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of CYP17A1 mRNA
|
CTD |
PMID:18630931 |
|
NCBI chr 1:255,476,861...255,484,547
Ensembl chr 1:255,476,861...255,482,974
|
|
| G
|
Cyp1a1
|
cytochrome P450, family 1, subfamily a, polypeptide 1
|
affects expression multiple interactions increases expression decreases expression increases stability
|
ISO
|
Arsenic Trioxide affects the expression of CYP1A1 mRNA [Tretinoin co-treated with Arsenic Trioxide] results in increased expression of CYP1A1 mRNA; Arsenic Trioxide inhibits the reaction [Benzo(a)pyrene results in increased activity of CYP1A1 protein]; Arsenic Trioxide inhibits the reaction [Dioxins results in increased activity of CYP1A1 protein]; Arsenic Trioxide inhibits the reaction [Methylcholanthrene results in increased expression of and results in increased activity of CYP1A1 protein]; Arsenic Trioxide inhibits the reaction [Methylcholanthrene results in increased expression of CYP1A1 mRNA]; Arsenic Trioxide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of and results in increased activity of CYP1A1 protein]; Arsenic Trioxide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]; verlukast promotes the reaction [Arsenic Trioxide results in decreased activity of CYP1A1 protein] Arsenic Trioxide results in increased expression of CYP1A1 mRNA [Arsenic Trioxide co-treated with Tetrachlorodibenzodioxin] results in increased stability of CYP1A1 mRNA; [Arsenic Trioxide co-treated with Tetrachlorodibenzodioxin] results in increased stability of CYP1A1 protein; Arsenic Trioxide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of and results in increased activity of CYP1A1 protein]; Arsenic Trioxide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]; Arsenic Trioxide promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of and results in increased activity of CYP1A1 protein]; Arsenic Trioxide promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]; Arsenic Trioxide promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 protein] Arsenic Trioxide results in decreased expression of CYP1A1 mRNA Arsenic Trioxide results in increased stability of CYP1A1 mRNA
|
CTD |
PMID:11678611 PMID:12490585 PMID:15894607 PMID:17530438 PMID:27829220 PMID:35676786 PMID:35872050 PMID:37423394 PMID:38758479 More...
|
|
NCBI chr 8:66,991,940...66,998,014
Ensembl chr 8:66,991,970...66,998,012
|
|
| G
|
Cyp1a2
|
cytochrome P450, family 1, subfamily a, polypeptide 2
|
multiple interactions increases expression
|
ISO
|
Arsenic Trioxide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of and results in increased activity of CYP1A2 protein]; Arsenic Trioxide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA] Arsenic Trioxide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA]; Arsenic Trioxide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 protein]; Arsenic Trioxide promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of and results in increased activity of CYP1A2 protein]; Arsenic Trioxide promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA] Arsenic Trioxide results in increased expression of CYP1A2 mRNA; Arsenic Trioxide results in increased expression of CYP1A2 protein
|
CTD |
PMID:35872050 PMID:37423394 |
|
NCBI chr 8:66,971,261...66,978,149
Ensembl chr 8:66,971,261...66,978,149
|
|
| G
|
Cyp1b1
|
cytochrome P450, family 1, subfamily b, polypeptide 1
|
affects expression decreases expression multiple interactions increases expression
|
ISO
|
Arsenic Trioxide affects the expression of CYP1B1 mRNA Arsenic Trioxide results in decreased expression of CYP1B1 protein [Tretinoin co-treated with Arsenic Trioxide] results in decreased expression of CYP1B1 mRNA; Resveratrol inhibits the reaction [Arsenic Trioxide results in decreased expression of CYP1B1 protein] Arsenic Trioxide results in increased expression of CYP1B1 mRNA
|
CTD |
PMID:15894607 PMID:17530438 PMID:29876539 PMID:38758479 |
|
NCBI chr 6:21,093,927...21,103,091
Ensembl chr 6:21,078,146...21,103,142
|
|
| G
|
Cyp24a1
|
cytochrome P450, family 24, subfamily a, polypeptide 1
|
decreases expression multiple interactions
|
ISO
|
Arsenic Trioxide results in decreased expression of CYP24A1 [Arsenic Trioxide results in decreased expression of CYP24A1] which results in increased activity of paricalcitol; Arsenic Trioxide inhibits the reaction [Cholecalciferol results in increased expression of CYP24A1 mRNA]
|
CTD |
PMID:15781666 PMID:16184197 |
|
NCBI chr 3:179,694,647...179,709,083
Ensembl chr 3:179,694,647...179,709,083
|
|
| G
|
Cyp26a1
|
cytochrome P450, family 26, subfamily a, polypeptide 1
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [Tretinoin results in increased expression of CYP26A1 mRNA]
|
CTD |
PMID:15688020 |
|
NCBI chr 1:244,883,822...244,887,657
Ensembl chr 1:244,883,752...244,887,657
|
|
| G
|
Cyp2a3
|
cytochrome P450, family 2, subfamily a, polypeptide 3
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of CYP2A4 mRNA
|
CTD |
PMID:38758479 |
|
NCBI chr 1:91,299,584...91,307,650
Ensembl chr 1:91,299,561...91,307,649
|
|
| G
|
Cyp2b3
|
cytochrome P450, family 2, subfamily b, polypeptide 3
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of CYP2B10 mRNA
|
CTD |
PMID:38758479 |
|
NCBI chr 1:90,780,468...90,859,852
|
|
| G
|
Cyp2c11
|
cytochrome P450, subfamily 2, polypeptide 11
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of CYP2C18 mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr 1:246,175,216...246,211,445
Ensembl chr 1:246,174,711...246,211,853
|
|
| G
|
Cyp2c6
|
cytochrome P450, family 2, subfamily C, polypeptide 6
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of CYP2C29 mRNA
|
CTD |
PMID:38758479 |
|
NCBI chr 1:247,879,058...247,916,804
Ensembl chr 1:247,879,078...247,916,798
|
|
| G
|
Cyp2d4
|
cytochrome P450, family 2, subfamily d, polypeptide 4
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to CYP2D6 protein]
|
CTD |
PMID:26598702 |
|
NCBI chr 7:115,762,662...115,771,832
Ensembl chr 7:115,761,696...115,771,837
|
|
| G
|
Cyp2e1
|
cytochrome P450, family 2, subfamily e, polypeptide 1
|
affects expression decreases expression
|
ISO
|
Arsenic Trioxide affects the expression of CYP2E1 mRNA Arsenic Trioxide results in decreased expression of CYP2E1 mRNA
|
CTD |
PMID:17530438 PMID:35676786 PMID:38758479 |
|
NCBI chr 1:205,269,967...205,280,365
Ensembl chr 1:205,267,505...205,293,495
|
|
| G
|
Cyp2j4
|
cytochrome P450, family 2, subfamily j, polypeptide 4
|
decreases response to substance increases expression
|
ISO
|
CYP2J2 protein results in decreased susceptibility to Arsenic Trioxide Arsenic Trioxide results in increased expression of CYP2J9 mRNA
|
CTD |
PMID:20707922 PMID:38758479 |
|
NCBI chr 5:116,295,691...116,323,219
Ensembl chr 5:116,295,694...116,323,042
|
|
| G
|
Cyp39a1
|
cytochrome P450, family 39, subfamily a, polypeptide 1
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of CYP39A1 mRNA
|
CTD |
PMID:15761015 |
|
NCBI chr 9:24,727,817...24,804,060
Ensembl chr 9:24,727,817...24,804,060
|
|
| G
|
Cyp3a18
|
cytochrome P450, family 3, subfamily a, polypeptide 18
|
multiple interactions increases expression
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to CYP3A43 protein] Arsenic Trioxide results in increased expression of CYP3A43 mRNA
|
CTD |
PMID:15761015 PMID:26598702 |
|
NCBI chr12:13,994,312...14,044,185
Ensembl chr12:13,994,311...14,045,788
|
|
| G
|
Cyp3a2
|
cytochrome P450, family 3, subfamily a, polypeptide 2
|
multiple interactions increases expression
|
ISO
|
Arsenic Trioxide inhibits the reaction [Rifampin results in increased expression of CYP3A4 protein] Arsenic Trioxide results in increased expression of CYP3A4 mRNA
|
CTD |
PMID:16184197 PMID:20458559 |
|
NCBI chr12:14,321,771...14,343,886
Ensembl chr12:14,321,771...14,343,857
|
|
| G
|
Cyp3a9
|
cytochrome P450, family 3, subfamily a, polypeptide 9
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of CYP3A13 mRNA
|
CTD |
PMID:38758479 |
|
NCBI chr12:21,919,955...21,960,160
Ensembl chr12:21,919,940...21,960,154
|
|
| G
|
Cyp4f18
|
cytochrome P450, family 4, subfamily f, polypeptide 18
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of CYP4F18 mRNA
|
CTD |
PMID:38758479 |
|
NCBI chr16:17,797,558...17,838,958
Ensembl chr16:17,740,001...17,838,958
|
|
| G
|
Cyp4f40
|
cytochrome P450, family 4, subfamily f, polypeptide 40
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of CYP4F11 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 7:12,342,121...12,357,974
Ensembl chr 7:12,342,590...12,356,733
|
|
| G
|
Cyp4f6
|
cytochrome P450, family 4, subfamily f, polypeptide 6
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of CYP4F16 mRNA
|
CTD |
PMID:38758479 |
|
NCBI chr 7:12,680,799...12,708,378
Ensembl chr 7:12,680,806...12,708,402
|
|
| G
|
Cyp7b1
|
cytochrome P450 family 7 subfamily B member 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of CYP7B1 mRNA
|
CTD |
PMID:17530438 PMID:26705709 |
|
NCBI chr 2:102,419,011...102,586,047
Ensembl chr 2:102,419,011...102,451,804
|
|
| G
|
Cystm1
|
cysteine-rich transmembrane module containing 1
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of CYSTM1 mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr18:28,219,861...28,287,574
Ensembl chr18:28,220,004...28,287,574
|
|
| G
|
Cytl1
|
cytokine like 1
|
multiple interactions decreases expression
|
ISO
|
[Tretinoin co-treated with Arsenic Trioxide] results in decreased expression of CYTL1 mRNA; Arsenic Trioxide inhibits the reaction [SP1 protein binds to CYTL1 promoter] Arsenic Trioxide results in decreased expression of CYTL1 mRNA
|
CTD |
PMID:15070760 PMID:15761015 PMID:15894607 |
|
NCBI chr14:77,278,635...77,283,645
Ensembl chr14:77,278,636...77,283,645
|
|
| G
|
Czib
|
CXXC motif containing zinc binding protein
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to CZIB protein]
|
CTD |
PMID:26598702 |
|
NCBI chr 5:127,875,408...127,885,100
Ensembl chr 5:127,877,173...127,886,538
|
|
| G
|
Dab2
|
DAB adaptor protein 2
|
affects expression decreases expression
|
ISO
|
Arsenic Trioxide affects the expression of DAB2 mRNA Arsenic Trioxide results in decreased expression of DAB2 mRNA
|
CTD |
PMID:22521957 PMID:28786057 |
|
NCBI chr 2:57,241,947...57,294,893
Ensembl chr 2:57,242,064...57,294,888
|
|
| G
|
Dab2ip
|
DAB2 interacting protein
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of DAB2IP mRNA
|
CTD |
PMID:22521957 |
|
NCBI chr 3:39,312,745...39,483,730
Ensembl chr 3:39,312,745...39,483,730
|
|
| G
|
Dach2
|
dachshund family transcription factor 2
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of DACH2 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr X:82,644,374...83,210,181
Ensembl chr X:82,644,128...83,210,000
|
|
| G
|
Dact1
|
dishevelled-binding antagonist of beta-catenin 1
|
decreases methylation decreases expression multiple interactions
|
ISO
|
Arsenic Trioxide results in decreased methylation of DACT1 promoter Arsenic Trioxide results in decreased expression of DACT1 mRNA [Arsenic Trioxide results in decreased methylation of DACT1 promoter] which results in increased expression of DACT1 mRNA
|
CTD |
PMID:21176356 PMID:27829220 |
|
NCBI chr 6:95,526,645...95,538,625
Ensembl chr 6:95,526,690...95,551,053
|
|
| G
|
Dad1
|
defender against cell death 1
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of DAD1 protein
|
CTD |
PMID:25419056 |
|
NCBI chr15:31,647,326...31,667,159
Ensembl chr15:31,647,326...31,667,287
|
|
| G
|
Dag1
|
dystroglycan 1
|
multiple interactions
|
ISO
|
[Tretinoin co-treated with Arsenic Trioxide] results in decreased expression of DAG1 mRNA
|
CTD |
PMID:15894607 |
|
NCBI chr 8:117,769,517...117,834,347
Ensembl chr 8:117,769,517...117,782,199
|
|
| G
|
Dapk2
|
death-associated protein kinase 2
|
multiple interactions increases expression
|
ISO
|
DAPK2 protein affects the reaction [Arsenic Trioxide results in increased cleavage of CASP3 protein]; TP73 protein affects the reaction [Arsenic Trioxide results in increased expression of DAPK2 mRNA]; TP73 protein affects the reaction [Arsenic Trioxide results in increased expression of DAPK2 protein] Arsenic Trioxide results in increased expression of DAPK2 mRNA; Arsenic Trioxide results in increased expression of DAPK2 protein
|
CTD |
PMID:28978663 |
|
NCBI chr 8:75,601,621...75,720,619
Ensembl chr 8:75,601,634...75,720,617
|
|
| G
|
Dapp1
|
dual adaptor of phosphotyrosine and 3-phosphoinositides 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of DAPP1 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 2:229,099,319...229,148,868
Ensembl chr 2:229,099,319...229,148,843
|
|
| G
|
Dars1
|
aspartyl-tRNA synthetase 1
|
increases expression multiple interactions
|
ISO
|
Arsenic Trioxide results in increased expression of DARS1 protein Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to DARS1 protein]
|
CTD |
PMID:25419056 PMID:26598702 |
|
NCBI chr13:42,410,351...42,465,467
Ensembl chr13:42,379,162...42,465,467
|
|
| G
|
Daxx
|
death-domain associated protein
|
multiple interactions decreases expression
|
ISO
|
Arsenic Trioxide affects the reaction [NR3C1 protein modified form binds to DAXX protein]; Arsenic Trioxide affects the reaction [PML protein modified form binds to DAXX protein]; Arsenic Trioxide inhibits the reaction [[DAXX protein binds to NR3C1 protein] which binds to TSC22D3 promoter]; Arsenic Trioxide inhibits the reaction [DAXX protein binds to CEBPB protein] Arsenic Trioxide results in decreased expression of DAXX protein
|
CTD |
PMID:17081986 PMID:19690170 |
|
NCBI chr20:4,971,973...4,978,062
Ensembl chr20:4,971,941...4,977,720
|
|
| G
|
Dazap1
|
DAZ associated protein 1
|
increases expression decreases expression
|
ISO
|
Arsenic Trioxide results in increased expression of DAZAP1 mRNA Arsenic Trioxide results in decreased expression of DAZAP1 mRNA
|
CTD |
PMID:20458559 PMID:39716349 |
|
NCBI chr 7:10,074,342...10,098,810
Ensembl chr 7:10,074,849...10,095,599
|
|
| G
|
Dazap2
|
DAZ associated protein 2
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of DAZAP2 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 7:133,593,503...133,599,044
Ensembl chr 7:133,593,512...133,599,047
|
|
| G
|
Dbh
|
dopamine beta-hydroxylase
|
decreases expression multiple interactions
|
ISO
|
Arsenic Trioxide results in decreased expression of DBH mRNA Taurine inhibits the reaction [Arsenic Trioxide results in decreased expression of DBH mRNA]
|
CTD |
PMID:23392890 PMID:23518225 |
|
NCBI chr 3:30,886,313...30,903,313
Ensembl chr 3:30,886,328...30,903,316
|
|
| G
|
Dbn1
|
drebrin 1
|
increases expression decreases expression
|
ISO
|
Arsenic Trioxide results in increased expression of DBN1 mRNA Arsenic Trioxide results in decreased expression of DBN1 mRNA
|
CTD |
PMID:19128835 PMID:20458559 |
|
NCBI chr17:9,155,729...9,170,121
Ensembl chr17:9,155,787...9,170,122
|
|
| G
|
Dbnl
|
drebrin-like
|
multiple interactions increases cleavage
|
ISO
|
benzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketone inhibits the reaction [Arsenic Trioxide results in increased cleavage of DBNL protein]
|
CTD |
PMID:15637062 |
|
NCBI chr14:84,880,085...84,895,122
Ensembl chr14:84,880,142...84,897,133
|
|
| G
|
Dbt
|
dihydrolipoamide branched chain transacylase E2
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of DBT mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 2:207,166,660...207,195,528
Ensembl chr 2:207,166,652...207,195,525
|
|
| G
|
Dcbld2
|
discoidin, CUB and LCCL domain containing 2
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of DCBLD2 mRNA
|
CTD |
PMID:26705709 |
|
NCBI chr11:55,594,691...55,649,113
Ensembl chr11:55,594,691...55,649,085
|
|
| G
|
Dcc
|
DCC netrin 1 receptor
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of DCC mRNA
|
CTD |
PMID:11940349 |
|
NCBI chr18:67,144,272...68,248,159
Ensembl chr18:67,149,179...68,247,541
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| G
|
Dclk1
|
doublecortin-like kinase 1
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of DCLK1 mRNA
|
CTD |
PMID:29633893 |
|
NCBI chr 2:141,567,215...141,861,088
Ensembl chr 2:141,571,983...141,861,090
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|
| G
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Dclre1c
|
DNA cross-link repair 1C
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of DCLRE1C mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr17:79,684,988...79,718,399
Ensembl chr17:79,678,698...79,718,734
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| G
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Dcn
|
decorin
|
decreases expression multiple interactions
|
ISO
|
Arsenic Trioxide results in decreased expression of DCN mRNA [Arsenic Trioxide co-treated with apatinib] results in decreased expression of DCN mRNA
|
CTD |
PMID:26705709 PMID:39223679 |
|
NCBI chr 7:34,167,973...34,208,004
Ensembl chr 7:34,163,011...34,218,926
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| G
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Dcp2
|
decapping mRNA 2
|
increases response to substance
|
ISO
|
DCP2 protein results in increased susceptibility to Arsenic Trioxide
|
CTD |
PMID:20707922 |
|
NCBI chr18:37,001,615...37,037,949
Ensembl chr18:37,001,615...37,049,939
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|
| G
|
Dctd
|
dCMP deaminase
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to DCTD protein]
|
CTD |
PMID:26598702 |
|
NCBI chr16:50,799,699...50,831,398
Ensembl chr16:50,787,875...50,831,186
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| G
|
Dctn1
|
dynactin subunit 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of DCTN1 mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr 4:117,228,722...117,261,528
Ensembl chr 4:117,219,349...117,261,528
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|
| G
|
Dcun1d3
|
defective in cullin neddylation 1 domain containing 3
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to DCUN1D3 protein]
|
CTD |
PMID:26598702 |
|
NCBI chr 1:183,674,364...183,717,002
Ensembl chr 1:75,527,981...75,529,932 Ensembl chr 1:75,527,981...75,529,932
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|
| G
|
Dcx
|
doublecortin
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of DCX mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr X:112,227,455...112,370,291
Ensembl chr X:112,227,455...112,304,161
|
|
| G
|
Ddb1
|
damage-specific DNA binding protein 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of DDB1 protein
|
CTD |
PMID:25419056 |
|
NCBI chr 1:216,677,810...216,703,605
Ensembl chr 1:216,677,810...216,703,596
|
|
| G
|
Ddb2
|
damage specific DNA binding protein 2
|
affects expression
|
ISO
|
Arsenic Trioxide affects the expression of DDB2 mRNA
|
CTD |
PMID:25873331 |
|
NCBI chr 3:97,640,923...97,667,617
Ensembl chr 3:97,640,579...97,664,066
|
|
| G
|
Ddc
|
dopa decarboxylase
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of DDC mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr14:90,592,304...90,682,830
Ensembl chr14:90,592,304...90,682,806
|
|
| G
|
Ddi2
|
DNA damage inducible 1 homolog 2
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to DDI2 protein]
|
CTD |
PMID:26598702 |
|
NCBI chr 5:159,272,625...159,318,365
Ensembl chr 5:159,272,625...159,318,310
|
|
| G
|
Ddit3
|
DNA-damage inducible transcript 3
|
affects localization increases expression multiple interactions affects expression affects response to substance
|
ISO EXP
|
Arsenic Trioxide affects the localization of DDIT3 protein Arsenic Trioxide results in increased expression of DDIT3 protein 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt inhibits the reaction [Arsenic Trioxide results in increased expression of DDIT3 protein]; 2-(4-chlorophenoxy)-N-(4-(2-(4-chlorophenoxy)acetamido)cyclohexyl)acetamide inhibits the reaction [Arsenic Trioxide results in increased expression of DDIT3 protein]; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid inhibits the reaction [Arsenic Trioxide results in increased expression of DDIT3 protein]; 4-phenylbutyric acid inhibits the reaction [Arsenic Trioxide results in increased expression of DDIT3 protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased expression of DDIT3 mRNA]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased expression of DDIT3 protein]; ATF4 protein promotes the reaction [Arsenic Trioxide results in increased expression of DDIT3 protein]; DDIT3 mutant form inhibits the reaction [Arsenic Trioxide results in increased activity of CASP3 protein]; DDIT3 mutant form inhibits the reaction [Arsenic Trioxide results in increased activity of CASP7 protein]; DDIT3 mutant form inhibits the reaction [Arsenic Trioxide results in increased degradation of CASP12 protein]; Thapsigargin promotes the reaction [Arsenic Trioxide results in increased expression of DDIT3 protein]; Thioctic Acid inhibits the reaction [Arsenic Trioxide results in increased expression of DDIT3 protein] Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased expression of DDIT3 protein]; ferrostatin-1 inhibits the reaction [Arsenic Trioxide results in increased expression of DDIT3 protein] Arsenic Trioxide results in increased expression of DDIT3 mRNA; Arsenic Trioxide results in increased expression of DDIT3 protein Arsenic Trioxide affects the expression of DDIT3 mRNA Acetylcysteine inhibits the reaction [Arsenic Trioxide promotes the reaction [Resveratrol results in increased expression of DDIT3 protein]]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased expression of DDIT3 protein]; Acetylcysteine inhibits the reaction [Resveratrol promotes the reaction [Arsenic Trioxide results in increased expression of DDIT3 protein]]; Arsenic Trioxide promotes the reaction [nilotinib results in increased expression of DDIT3 mRNA]; Arsenic Trioxide promotes the reaction [Resveratrol results in increased expression of DDIT3 protein]; Atrazine promotes the reaction [Arsenic Trioxide results in increased expression of DDIT3 mRNA]; DDIT3 affects the reaction [Arsenic Trioxide results in increased expression of TNFRSF10B]; DDIT3 mutant form inhibits the reaction [Arsenic Trioxide results in increased expression of TNFRSF10B protein]; DDIT3 results in increased susceptibility to [Arsenic Trioxide co-treated with TNFSF10]; MT2A protein promotes the reaction [Arsenic Trioxide results in increased expression of DDIT3 protein]; Resveratrol promotes the reaction [Arsenic Trioxide results in increased expression of DDIT3 protein]; sulforaphane promotes the reaction [Arsenic Trioxide results in increased expression of DDIT3 protein] DDIT3 affects the susceptibility to Arsenic Trioxide
|
CTD |
PMID:11678611 PMID:12749819 PMID:12883267 PMID:15493360 PMID:18172319 PMID:19939880 PMID:20458559 PMID:20501519 PMID:21145380 PMID:21533816 PMID:22922937 PMID:22959511 PMID:23664956 PMID:23883479 PMID:23892647 PMID:24157283 PMID:24356939 PMID:25258189 PMID:26772155 PMID:27461142 PMID:27638049 PMID:34091186 PMID:35195477 More...
|
|
NCBI chr 7:65,001,695...65,006,517
Ensembl chr 7:65,005,501...65,006,509
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|
| G
|
Ddit4
|
DNA-damage-inducible transcript 4
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of DDIT4 mRNA
|
CTD |
PMID:22521957 |
|
NCBI chr20:28,434,938...28,437,037
Ensembl chr20:28,434,944...28,437,037
|
|
| G
|
Ddr2
|
discoidin domain receptor tyrosine kinase 2
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of DDR2 protein
|
CTD |
PMID:30093655 |
|
NCBI chr13:84,726,412...84,851,032
Ensembl chr13:84,731,180...84,850,288
|
|
| G
|
Ddt
|
D-dopachrome tautomerase
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to DDT protein]
|
CTD |
PMID:26598702 |
|
NCBI chr20:12,883,025...12,886,121
|
|
| G
|
Ddx1
|
DEAD-box helicase 1
|
multiple interactions decreases expression
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to DDX1 protein] Arsenic Trioxide results in decreased expression of DDX1 protein
|
CTD |
PMID:25419056 PMID:26598702 |
|
NCBI chr 6:41,725,365...41,756,236
Ensembl chr 6:41,725,367...41,758,302
|
|
| G
|
Ddx21
|
DExD-box helicase 21
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of DDX21 protein
|
CTD |
PMID:25419056 |
|
NCBI chr20:31,077,044...31,097,238
Ensembl chr20:31,077,045...31,097,238
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|
| G
|
Ddx39b
|
DExD-box helicase 39B
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of DDX39B protein
|
CTD |
PMID:25419056 |
|
NCBI chr20:3,577,200...3,589,651
Ensembl chr20:3,576,734...3,589,651
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|
| G
|
Ddx3y
|
DEAD box helicase 3, Y-linked
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of DDX3Y mRNA; Arsenic Trioxide results in decreased expression of DDX3Y protein
|
CTD |
PMID:22581830 |
|
NCBI chr Y:1,190,042...1,210,699
Ensembl chr Y:1,191,242...1,210,650
|
|
| G
|
Ddx41
|
DEAD-box helicase 41
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of DDX41 mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr17:9,108,030...9,113,562
Ensembl chr17:9,108,074...9,113,561
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|
| G
|
Ddx5
|
DEAD-box helicase 5
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of DDX5 protein
|
CTD |
PMID:25419056 |
|
NCBI chr10:92,224,393...92,231,928
Ensembl chr10:92,224,395...92,231,300
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|
| G
|
Decr1
|
2,4-dienoyl-CoA reductase 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of DECR1 mRNA
|
CTD |
PMID:22521957 |
|
NCBI chr 5:34,208,195...34,236,074
Ensembl chr 5:34,208,195...34,236,033
|
|
| G
|
Dedd2
|
death effector domain containing 2
|
multiple interactions
|
ISO
|
[sanguinarine co-treated with Arsenic Trioxide] results in increased expression of DEDD2 mRNA
|
CTD |
PMID:24345465 |
|
NCBI chr 1:89,916,906...89,934,663
Ensembl chr 1:89,919,524...89,936,804
|
|
| G
|
Dennd2b
|
DENN domain containing 2B
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of DENND2B mRNA
|
CTD |
PMID:22521957 |
|
NCBI chr 1:172,978,895...173,129,623
Ensembl chr 1:172,978,895...173,129,810
|
|
| G
|
Denr
|
density regulated reinitiation and release factor
|
increases expression multiple interactions
|
ISO
|
Arsenic Trioxide results in increased expression of DENR mRNA Metformin inhibits the reaction [Arsenic Trioxide results in increased expression of DENR mRNA]
|
CTD |
PMID:29095437 |
|
NCBI chr12:38,323,433...38,346,207
Ensembl chr12:38,323,445...38,344,797
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|
| G
|
Depdc1
|
DEP domain containing 1
|
decreases expression increases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of DEPDC1 mRNA Arsenic Trioxide results in increased expression of DEPDC1 mRNA
|
CTD |
PMID:22521957 PMID:26705709 |
|
NCBI chr 2:251,343,250...251,376,709
Ensembl chr 2:251,343,281...251,376,709
|
|
| G
|
Deptor
|
DEP domain containing MTOR-interacting protein
|
multiple interactions
|
ISO
|
[Arsenic Trioxide co-treated with apatinib] results in decreased expression of DEPTOR mRNA
|
CTD |
PMID:39223679 |
|
NCBI chr 7:88,404,745...88,574,065
Ensembl chr 7:88,404,620...88,574,041
|
|
| G
|
Derl1
|
derlin 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of DERL1 mRNA
|
CTD |
PMID:35676786 |
|
NCBI chr 7:91,293,963...91,316,639
Ensembl chr 7:91,258,382...91,316,678
|
|
| G
|
Des
|
desmin
|
decreases expression multiple interactions
|
EXP
|
Arsenic Trioxide results in decreased expression of DES mRNA Phloretin inhibits the reaction [Arsenic Trioxide results in decreased expression of DES mRNA]
|
CTD |
PMID:34037972 |
|
NCBI chr 9:84,299,626...84,307,344
Ensembl chr 9:84,298,447...84,307,347
|
|
| G
|
Desi2
|
desumoylating isopeptidase 2
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of DESI2 mRNA
|
CTD |
PMID:20458559 PMID:22521957 |
|
NCBI chr13:92,493,765...92,543,307
Ensembl chr13:92,493,989...92,564,981
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|
| G
|
Dexi
|
Dexi homolog
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of DEXI mRNA
|
CTD |
PMID:35676786 |
|
NCBI chr10:5,632,400...5,645,653
Ensembl chr10:5,632,961...5,645,648
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|
| G
|
Dffa
|
DNA fragmentation factor subunit alpha
|
increases expression multiple interactions
|
ISO EXP
|
Arsenic Trioxide results in increased expression of DFFA mRNA Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to DFFA protein]
|
CTD |
PMID:17530438 PMID:19730151 PMID:26598702 |
|
NCBI chr 5:164,823,807...164,836,729
Ensembl chr 5:164,823,807...164,836,728
|
|
| G
|
Dffb
|
DNA fragmentation factor subunit beta
|
increases expression multiple interactions decreases expression
|
ISO
|
Arsenic Trioxide results in increased expression of DFFB mRNA Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to DFFB protein] Arsenic Trioxide results in decreased expression of DFFB mRNA
|
CTD |
PMID:17530438 PMID:26598702 PMID:34108876 |
|
NCBI chr 5:169,804,873...169,817,157
Ensembl chr 5:169,804,889...169,817,225
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|
| G
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Dgcr8
|
DGCR8 microprocessor complex subunit
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of DGCR8 mRNA
|
CTD |
PMID:22521957 |
|
NCBI chr11:96,208,959...96,241,560
Ensembl chr11:96,209,038...96,241,551
|
|
| G
|
Dgki
|
diacylglycerol kinase, iota
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of DGKI mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 4:66,377,897...66,839,790
Ensembl chr 4:66,387,126...66,990,832
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|
| G
|
Dhrs1
|
dehydrogenase/reductase 1
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to DHRS1 protein]
|
CTD |
PMID:26598702 |
|
NCBI chr15:33,206,449...33,213,776
Ensembl chr15:33,206,451...33,213,734
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|
| G
|
Dhrs2
|
dehydrogenase/reductase 2
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of DHRS2 mRNA
|
CTD |
PMID:26705709 |
|
NCBI chr15:32,658,855...32,673,591
Ensembl chr15:32,659,223...32,673,588
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|
| G
|
Dhrs7
|
dehydrogenase/reductase 7
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of DHRS7 mRNA
|
CTD |
PMID:27829220 |
|
NCBI chr 6:97,068,149...97,083,744
Ensembl chr 6:97,068,149...97,083,744
|
|
| G
|
Dhrs9
|
dehydrogenase/reductase 9
|
multiple interactions
|
ISO
|
[Tretinoin co-treated with Arsenic Trioxide] results in increased expression of DHRS9 mRNA
|
CTD |
PMID:15894607 |
|
NCBI chr 3:74,553,357...74,579,535
Ensembl chr 3:74,555,606...74,581,376
|
|
| G
|
Dhrsx
|
dehydrogenase/reductase X-linked
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of DHRSX mRNA
|
CTD |
PMID:26705709 |
|
NCBI chr12:21,413,563...21,418,319
Ensembl chr12:21,413,575...21,418,319
|
|
| G
|
Dhtkd1
|
dehydrogenase E1 and transketolase domain containing 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of DHTKD1 protein
|
CTD |
PMID:25419056 |
|
NCBI chr17:77,242,512...77,316,074
Ensembl chr17:77,264,514...77,316,071
|
|
| G
|
Dhx15
|
DEAH-box helicase 15
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of DHX15 protein
|
CTD |
PMID:29163777 |
|
NCBI chr14:62,999,886...63,037,829
Ensembl chr14:62,999,877...63,037,828
|
|
| G
|
Dhx9
|
DExH-box helicase 9
|
increases expression multiple interactions decreases expression
|
ISO
|
Arsenic Trioxide results in increased expression of DHX9 mRNA Metformin inhibits the reaction [Arsenic Trioxide results in increased expression of DHX9 mRNA] Arsenic Trioxide results in decreased expression of DHX9 mRNA
|
CTD |
PMID:29095437 PMID:39716349 |
|
NCBI chr13:68,152,813...68,189,580
Ensembl chr13:68,152,813...68,189,546
|
|
| G
|
Diablo
|
diablo, IAP-binding mitochondrial protein
|
multiple interactions
|
ISO
|
[Arsenic Trioxide co-treated with Curcumin] results in increased expression of DIABLO protein
|
CTD |
PMID:27430728 |
|
NCBI chr12:38,716,668...38,731,285
Ensembl chr12:38,716,668...38,731,265
|
|
| G
|
Diaph1
|
diaphanous-related formin 1
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of DIAPH1 mRNA
|
CTD |
PMID:19128835 |
|
NCBI chr18:29,920,889...30,020,280
Ensembl chr18:29,920,889...30,020,280
|
|
| G
|
Diaph3
|
diaphanous-related formin 3
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of DIAPH3 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr15:68,951,992...69,421,623
Ensembl chr15:68,951,989...69,421,552
|
|
| G
|
Dip2b
|
disco-interacting protein 2 homolog B
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of DIP2B mRNA
|
CTD |
PMID:35676786 |
|
NCBI chr 7:133,053,393...133,231,430
Ensembl chr 7:133,053,401...133,228,874
|
|
| G
|
Dipk1a
|
divergent protein kinase domain 1A
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of DIPK1A mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr14:1,917,353...1,988,188
Ensembl chr14:1,917,324...1,988,678
|
|
| G
|
Diras3
|
DIRAS family GTPase 3
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of DIRAS3 mRNA
|
CTD |
PMID:26705709 |
|
NCBI chr 6:136,346,157...136,347,371
Ensembl chr 6:136,346,154...136,348,376
|
|
| G
|
Dkk1
|
dickkopf WNT signaling pathway inhibitor 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of DKK1 mRNA
|
CTD |
PMID:17547211 |
|
NCBI chr 1:237,794,969...237,798,650
Ensembl chr 1:237,794,969...237,798,650
|
|
| G
|
Dkk3
|
dickkopf WNT signaling pathway inhibitor 3
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of DKK3 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 1:175,672,834...175,715,867
Ensembl chr 1:175,672,834...175,715,186
|
|
| G
|
Dlc1
|
DLC1 Rho GTPase activating protein
|
decreases methylation increases expression
|
ISO
|
Arsenic Trioxide results in decreased methylation of DLC1 gene Arsenic Trioxide results in increased expression of DLC1 mRNA
|
CTD |
PMID:25534098 |
|
NCBI chr16:61,954,177...62,374,819
Ensembl chr16:61,995,001...62,374,819
|
|
| G
|
Dlg1
|
discs large MAGUK scaffold protein 1
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of DLG1 mRNA
|
CTD |
PMID:24831965 |
|
NCBI chr11:82,416,853...82,607,797
Ensembl chr11:82,416,853...82,607,797
|
|
| G
|
Dlg2
|
discs large MAGUK scaffold protein 2
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of DLG2 mRNA
|
CTD |
PMID:24831965 |
|
NCBI chr 1:153,864,545...155,916,238
Ensembl chr 1:153,865,299...155,916,215
|
|
| G
|
Dlg3
|
discs large MAGUK scaffold protein 3
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of DLG3 mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr X:69,899,694...69,951,928
Ensembl chr X:69,900,003...69,950,696
|
|
| G
|
Dlgap4
|
DLG associated protein 4
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of DLGAP4 mRNA
|
CTD |
PMID:22521957 |
|
NCBI chr 3:165,584,271...165,731,868
Ensembl chr 3:165,584,360...165,730,604
|
|
| G
|
Dlk1
|
delta like non-canonical Notch ligand 1
|
affects response to substance
|
ISO
|
DLK1 protein affects the susceptibility to Arsenic Trioxide
|
CTD |
PMID:18575777 |
|
NCBI chr 6:134,192,491...134,199,779
Ensembl chr 6:134,192,518...134,200,529
|
|
| G
|
Dll4
|
delta like canonical Notch ligand 4
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of DLL4
|
CTD |
PMID:25088040 |
|
NCBI chr 3:126,770,945...126,780,769
Ensembl chr 3:126,770,794...126,780,763
|
|
| G
|
Dlx1
|
distal-less homeobox 1
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of DLX1 mRNA
|
CTD |
PMID:26705709 |
|
NCBI chr 3:76,763,864...76,768,454
Ensembl chr 3:76,763,500...76,768,447
|
|
| G
|
Dlx3
|
distal-less homeobox 3
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of DLX3 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr10:80,561,335...80,566,730
Ensembl chr10:80,561,335...80,566,711
|
|
| G
|
Dlx4
|
distal-less homeobox 4
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of DLX4 mRNA
|
CTD |
PMID:22521957 |
|
NCBI chr10:80,581,878...80,587,272
Ensembl chr10:80,582,303...80,587,294
|
|
| G
|
Dmkn
|
dermokine
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of DMKN mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr 1:95,140,737...95,158,676
Ensembl chr 1:95,141,620...95,157,439
|
|
| G
|
Dmxl1
|
Dmx-like 1
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of DMXL1 protein
|
CTD |
PMID:30093655 |
|
NCBI chr18:45,179,505...45,349,999
Ensembl chr18:45,179,551...45,356,406
|
|
| G
|
Dnaaf11
|
dynein axonemal assembly factor 11
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of LRRC6 mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr 7:100,033,843...100,134,979
Ensembl chr 7:100,034,202...100,135,179
|
|
| G
|
Dnah7
|
dynein, axonemal, heavy chain 7
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of DNAH7 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 9:62,454,838...62,760,504
Ensembl chr 9:62,454,838...62,756,730
|
|
| G
|
Dnai3
|
dynein axonemal intermediate chain 3
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of DNAI3 mRNA
|
CTD |
PMID:26705709 |
|
NCBI chr 2:237,608,202...237,666,465
Ensembl chr 2:237,604,068...237,666,465
|
|
| G
|
Dnaja1
|
DnaJ heat shock protein family (Hsp40) member A1
|
increases expression decreases expression
|
ISO
|
Arsenic Trioxide results in increased expression of DNAJA1 mRNA Arsenic Trioxide results in decreased expression of DNAJA1 mRNA
|
CTD |
PMID:19417148 PMID:27829220 PMID:35676786 |
|
NCBI chr 5:60,638,404...60,649,315
Ensembl chr 5:60,638,410...60,650,160
|
|
| G
|
Dnaja4
|
DnaJ heat shock protein family (Hsp40) member A4
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to DNAJA4 protein]
|
CTD |
PMID:26598702 |
|
NCBI chr 8:63,975,177...63,998,836
Ensembl chr 8:63,981,559...63,998,836
|
|
| G
|
Dnajb1
|
DnaJ heat shock protein family (Hsp40) member B1
|
increases expression multiple interactions
|
ISO
|
Arsenic Trioxide results in increased expression of DNAJB1 mRNA; Arsenic Trioxide results in increased expression of DNAJB1 protein KNK 437 inhibits the reaction [Arsenic Trioxide results in increased expression of DNAJB1 protein]
|
CTD |
PMID:19417148 PMID:20458559 PMID:20724260 PMID:24356939 |
|
NCBI chr19:41,427,453...41,431,141
Ensembl chr19:41,427,453...41,431,416
|
|
| G
|
Dnajb11
|
DnaJ heat shock protein family (Hsp40) member B11
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to DNAJB11 protein]
|
CTD |
PMID:26598702 |
|
NCBI chr11:91,656,334...91,672,800
Ensembl chr11:91,656,335...91,672,800
|
|
| G
|
Dnajb2
|
DnaJ heat shock protein family (Hsp40) member B2
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of DNAJB2 mRNA
|
CTD |
PMID:19417148 |
|
NCBI chr 9:84,179,702...84,187,942
Ensembl chr 9:84,179,695...84,187,942
|
|
| G
|
Dnajb4
|
DnaJ heat shock protein family (Hsp40) member B4
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of DNAJB4 mRNA
|
CTD |
PMID:15761015 PMID:19417148 PMID:24356939 PMID:25258189 |
|
NCBI chr 2:243,790,296...243,819,042
Ensembl chr 2:243,790,297...243,819,042
|
|
| G
|
Dnajb6
|
DnaJ heat shock protein family (Hsp40) member B6
|
increases expression decreases expression
|
ISO
|
Arsenic Trioxide results in increased expression of DNAJB6 mRNA Arsenic Trioxide results in decreased expression of DNAJB6 mRNA
|
CTD |
PMID:19417148 PMID:39716349 |
|
NCBI chr 4:6,010,081...6,232,052
Ensembl chr 4:6,128,070...6,232,005
|
|
| G
|
Dnajb9
|
DnaJ heat shock protein family (Hsp40) member B9
|
multiple interactions
|
ISO
|
[Tretinoin co-treated with Arsenic Trioxide] results in decreased expression of DNAJB9 mRNA
|
CTD |
PMID:15894607 |
|
NCBI chr 6:66,997,842...67,007,371
Ensembl chr 6:66,997,842...67,009,344
|
|
| G
|
Dnajc10
|
DnaJ heat shock protein family (Hsp40) member C10
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of DNAJC10 protein
|
CTD |
PMID:25419056 |
|
NCBI chr 3:85,636,890...85,679,620
Ensembl chr 3:85,639,589...85,689,368
|
|
| G
|
Dnajc7
|
DnaJ heat shock protein family (Hsp40) member C7
|
decreases expression multiple interactions
|
ISO
|
Arsenic Trioxide results in decreased expression of DNAJC7 protein Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to DNAJC7 protein]
|
CTD |
PMID:25419056 PMID:26598702 |
|
NCBI chr10:86,018,977...86,055,419
Ensembl chr10:86,018,961...86,055,489
|
|
| G
|
Dnajc9
|
DnaJ heat shock protein family (Hsp40) member C9
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of DNAJC9 mRNA
|
CTD |
PMID:15761015 |
|
NCBI chr15:3,970,843...4,003,009
Ensembl chr15:3,970,114...3,977,304
|
|
| G
|
Dnase1l1
|
deoxyribonuclease 1-like 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of DNASE1L1 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr X:157,208,230...157,216,812
Ensembl chr X:157,208,230...157,216,711
|
|
| G
|
Dnm1l
|
dynamin 1-like
|
multiple interactions decreases expression affects expression
|
ISO EXP
|
ATF4 protein promotes the reaction [Arsenic Trioxide affects the expression of DNM1L protein modified form]; salvianolic acid A inhibits the reaction [Arsenic Trioxide results in decreased expression of DNM1L protein]
|
CTD |
PMID:27638049 PMID:29867492 |
|
NCBI chr11:98,084,049...98,135,663
Ensembl chr11:98,085,397...98,137,420
|
|
| G
|
Dnm2
|
dynamin 2
|
multiple interactions
|
ISO
|
[Arsenic Trioxide co-treated with nilotinib] affects the expression of DNM2 mRNA
|
CTD |
PMID:28786057 |
|
NCBI chr 8:28,254,344...28,336,297
Ensembl chr 8:28,254,529...28,336,295
|
|
| G
|
Dnm3
|
dynamin 3
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of DNM3 mRNA
|
CTD |
PMID:26705709 |
|
NCBI chr13:76,892,381...77,371,346
Ensembl chr13:76,892,171...77,371,350
|
|
| G
|
Dnmbp
|
dynamin binding protein
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of DNMBP mRNA
|
CTD |
PMID:27829220 |
|
NCBI chr 1:252,685,406...252,778,642
Ensembl chr 1:252,685,406...252,778,688
|
|
| G
|
Dnmt1
|
DNA methyltransferase 1
|
decreases expression increases expression multiple interactions decreases activity
|
EXP ISO
|
Arsenic Trioxide results in decreased expression of DNMT1 mRNA Arsenic Trioxide results in decreased expression of DNMT1 mRNA; Arsenic Trioxide results in decreased expression of DNMT1 protein Arsenic Trioxide results in increased expression of DNMT1 mRNA [Arsenic Trioxide co-treated with Tamoxifen] results in decreased expression of DNMT1 mRNA; [Arsenic Trioxide co-treated with Tamoxifen] results in decreased expression of DNMT1 protein Arsenic Trioxide inhibits the reaction [DNMT1 protein binds to ESR1 promoter]; Arsenic Trioxide promotes the reaction [Azacitidine results in decreased expression of DNMT1 protein]; S-Adenosylmethionine inhibits the reaction [Arsenic Trioxide inhibits the reaction [DNMT1 protein binds to ESR1 promoter]]; S-Adenosylmethionine inhibits the reaction [Arsenic Trioxide results in decreased expression of DNMT1 protein] Arsenic Trioxide results in decreased activity of DNMT1 protein
|
CTD |
PMID:16613325 PMID:17490527 PMID:19679824 PMID:20596618 PMID:21176356 PMID:21687957 PMID:22558281 PMID:23159075 PMID:24993472 PMID:25534098 PMID:28901456 PMID:29159499 PMID:29223816 More...
|
|
NCBI chr 8:27,716,797...27,763,405
Ensembl chr 8:27,716,797...27,763,119
|
|
| G
|
Dnmt3a
|
DNA methyltransferase 3 alpha
|
decreases expression decreases activity multiple interactions increases expression
|
EXP ISO
|
Arsenic Trioxide results in decreased expression of DNMT3A mRNA Arsenic Trioxide results in decreased expression of DNMT3A; Arsenic Trioxide results in decreased expression of DNMT3A mRNA; Arsenic Trioxide results in decreased expression of DNMT3A protein Arsenic Trioxide results in decreased activity of DNMT3A protein [[Arsenic Trioxide results in increased expression of DNMT3A protein] which results in increased methylation of MEG3 promoter] which results in decreased expression of MEG3 protein; S-Adenosylmethionine inhibits the reaction [Arsenic Trioxide results in decreased expression of DNMT3A protein] Arsenic Trioxide results in increased expression of DNMT3A mRNA; Arsenic Trioxide results in increased expression of DNMT3A protein
|
CTD |
PMID:12667347 PMID:12679007 PMID:17490527 PMID:20416177 PMID:20596618 PMID:21176356 PMID:22558281 PMID:25534098 PMID:29159499 PMID:29223816 PMID:37424815 More...
|
|
NCBI chr 6:32,507,316...32,621,678
Ensembl chr 6:32,512,070...32,614,970
|
|
| G
|
Dnmt3b
|
DNA methyltransferase 3 beta
|
decreases expression decreases activity increases expression
|
ISO EXP
|
Arsenic Trioxide results in decreased expression of DNMT3B protein Arsenic Trioxide results in decreased activity of DNMT3B protein Arsenic Trioxide results in increased expression of DNMT3B mRNA Arsenic Trioxide results in decreased expression of DNMT3B mRNA Arsenic Trioxide results in decreased expression of DNMT3B; Arsenic Trioxide results in decreased expression of DNMT3B mRNA
|
CTD |
PMID:12667347 PMID:12679007 PMID:17490527 PMID:19679824 PMID:20416177 PMID:20596618 PMID:21176356 PMID:25534098 PMID:29159499 PMID:29223816 More...
|
|
NCBI chr 3:162,590,777...162,629,313
Ensembl chr 3:162,604,037...162,629,313
|
|
| G
|
Dnmt3l
|
DNA methyltransferase 3 like
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to DNMT3L protein]
|
CTD |
PMID:26598702 |
|
NCBI chr20:10,614,591...10,628,989
Ensembl chr20:10,614,591...10,629,168
|
|
| G
|
Dock3
|
dedicator of cyto-kinesis 3
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of DOCK3 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 8:116,431,158...116,782,218
Ensembl chr 8:116,431,159...116,782,195
|
|
| G
|
Dok3
|
docking protein 3
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to DOK3 protein]
|
CTD |
PMID:26598702 |
|
NCBI chr17:9,114,763...9,121,781
Ensembl chr17:9,114,762...9,120,335
|
|
| G
|
Dok5
|
docking protein 5
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of DOK5 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 3:179,934,419...180,071,334
Ensembl chr 3:179,934,552...180,071,333
|
|
| G
|
Dok7
|
docking protein 7
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of DOK7 mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr14:79,890,051...79,924,081
Ensembl chr14:79,891,367...79,932,252
|
|
| G
|
Dpagt1
|
dolichyl-phosphate N-acetylglucosaminephosphotransferase 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of DPAGT1 mRNA
|
CTD |
PMID:22521957 |
|
NCBI chr 8:53,560,869...53,567,625
Ensembl chr 8:53,555,239...53,567,898
|
|
| G
|
Dpep1
|
dipeptidase 1
|
increases expression multiple interactions decreases expression
|
ISO
|
Arsenic Trioxide results in increased expression of DPEP1 mRNA Metformin inhibits the reaction [Arsenic Trioxide results in increased expression of DPEP1 mRNA] Arsenic Trioxide results in decreased expression of DPEP1 mRNA
|
CTD |
PMID:29095437 PMID:39716349 |
|
NCBI chr19:68,118,270...68,143,781
Ensembl chr19:68,118,453...68,143,775
|
|
| G
|
Dph2
|
diphthamide biosynthesis 2
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to DPH2 protein]
|
CTD |
PMID:26598702 |
|
NCBI chr 5:136,713,868...136,716,828
|
|
| G
|
Dpp4
|
dipeptidylpeptidase 4
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of DPP4 mRNA
|
CTD |
PMID:26238599 PMID:29355690 |
|
NCBI chr 3:67,370,794...67,452,422
Ensembl chr 3:67,370,804...67,452,422
|
|
| G
|
Dpt
|
dermatopontin
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of DPT mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr13:79,656,341...79,684,759
Ensembl chr13:79,655,985...79,684,758
|
|
| G
|
Dpy19l1
|
dpy-19 like C-mannosyltransferase 1
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of DPY19L1 mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr 8:31,209,025...31,297,485
Ensembl chr 8:31,209,025...31,297,518
|
|
| G
|
Dpyd
|
dihydropyrimidine dehydrogenase
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of DPYD mRNA
|
CTD |
PMID:22521957 |
|
NCBI chr 2:209,293,902...210,159,777
Ensembl chr 2:209,293,929...210,159,778
|
|
| G
|
Dpysl2
|
dihydropyrimidinase-like 2
|
increases expression affects expression
|
ISO
|
Arsenic Trioxide results in increased expression of DPYSL2 mRNA Arsenic Trioxide affects the expression of DPYSL2 protein
|
CTD |
PMID:19364129 PMID:20458559 |
|
NCBI chr15:45,181,041...45,287,065
Ensembl chr15:45,181,041...45,287,065
|
|
| G
|
Dpysl3
|
dihydropyrimidinase-like 3
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of DPYSL3 protein
|
CTD |
PMID:25419056 |
|
NCBI chr18:35,625,357...35,731,152
Ensembl chr18:35,625,357...35,731,152
|
|
| G
|
Dram1
|
DNA-damage regulated autophagy modulator 1
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of DRAM1 mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr 7:24,630,233...24,665,270
Ensembl chr 7:24,630,238...24,664,354
|
|
| G
|
Drg1
|
developmentally regulated GTP binding protein 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of DRG1 mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr14:82,328,320...82,344,416
Ensembl chr14:82,328,320...82,344,348
|
|
| G
|
Dsc2
|
desmocollin 2
|
decreases response to substance
|
ISO
|
DSC2 protein results in decreased susceptibility to Arsenic Trioxide
|
CTD |
PMID:20707922 |
|
NCBI chr18:11,725,466...11,757,591
Ensembl chr18:11,725,466...11,757,466
|
|
| G
|
Dsg2
|
desmoglein 2
|
decreases response to substance
|
ISO
|
DSG2 protein results in decreased susceptibility to Arsenic Trioxide
|
CTD |
PMID:20707922 |
|
NCBI chr18:12,121,287...12,179,590
Ensembl chr18:12,121,181...12,179,590
|
|
| G
|
Dsg4
|
desmoglein 4
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of DSG4 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr18:11,995,902...12,032,908
Ensembl chr18:11,995,902...12,032,908
|
|
| G
|
Dsp
|
desmoplakin
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of DSP protein
|
CTD |
PMID:25419056 |
|
NCBI chr17:26,829,153...26,877,419
Ensembl chr17:26,829,153...26,877,121
|
|
| G
|
Dst
|
dystonin
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of DST mRNA
|
CTD |
PMID:22521957 |
|
NCBI chr 9:43,631,716...44,025,535
Ensembl chr 9:43,631,517...44,025,533
|
|
| G
|
Dtl
|
denticleless E3 ubiquitin protein ligase homolog
|
increases sumoylation
|
ISO
|
Arsenic Trioxide results in increased sumoylation of DTL protein
|
CTD |
PMID:28318385 |
|
NCBI chr13:105,646,908...105,685,921
Ensembl chr13:105,646,908...105,686,174
|
|
| G
|
Dtymk
|
deoxythymidylate kinase
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of DTYMK mRNA
|
CTD |
PMID:35676786 |
|
NCBI chr 9:101,762,899...101,771,733
Ensembl chr 9:101,762,899...101,774,504
|
|
| G
|
Duox2
|
dual oxidase 2
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of DUOX2 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 3:129,680,543...129,698,886
Ensembl chr 3:129,680,546...129,699,203
|
|
| G
|
Dus2
|
dihydrouridine synthase 2
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of DUS2 protein
|
CTD |
PMID:30093655 |
|
NCBI chr19:50,816,306...50,864,559
Ensembl chr19:50,816,310...50,864,559
|
|
| G
|
Dusp10
|
dual specificity phosphatase 10
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of DUSP10 mRNA
|
CTD |
PMID:24356939 |
|
NCBI chr13:98,145,317...98,183,304
Ensembl chr13:98,145,893...98,183,304
|
|
| G
|
Dusp16
|
dual specificity phosphatase 16
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of DUSP16 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 4:169,278,118...169,361,508
Ensembl chr 4:169,278,118...169,361,508
|
|
| G
|
Dusp2
|
dual specificity phosphatase 2
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of DUSP2 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 3:135,009,636...135,011,821
Ensembl chr 3:135,009,590...135,011,809
|
|
| G
|
Dusp4
|
dual specificity phosphatase 4
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of DUSP4 mRNA
|
CTD |
PMID:15725085 |
|
NCBI chr16:64,079,893...64,101,396
Ensembl chr16:64,079,893...64,093,700
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Dusp5
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dual specificity phosphatase 5
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decreases expression
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ISO
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Arsenic Trioxide results in decreased expression of DUSP5 mRNA
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CTD |
PMID:20016248 |
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NCBI chr 1:262,543,774...262,557,201
Ensembl chr 1:262,543,738...262,562,417
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Dusp7
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dual specificity phosphatase 7
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decreases expression
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ISO
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Arsenic Trioxide results in decreased expression of DUSP7 mRNA
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CTD |
PMID:20458559 |
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NCBI chr 8:115,888,091...115,895,126
Ensembl chr 8:115,887,892...115,895,126
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Dusp8
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dual specificity phosphatase 8
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increases expression
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ISO
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Arsenic Trioxide results in increased expression of DUSP8 mRNA
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CTD |
PMID:20458559 PMID:39716349 |
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NCBI chr 1:206,596,912...206,613,728
Ensembl chr 1:206,598,942...206,612,441
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Dync1h1
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dynein cytoplasmic 1 heavy chain 1
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increases expression
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ISO
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Arsenic Trioxide results in increased expression of DYNC1H1 mRNA
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CTD |
PMID:15725085 PMID:26705709 |
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NCBI chr 6:135,436,375...135,502,117
Ensembl chr 6:135,430,750...135,502,116
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Dync1i2
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dynein cytoplasmic 1 intermediate chain 2
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decreases expression
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ISO
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Arsenic Trioxide results in decreased expression of DYNC1I2 mRNA
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CTD |
PMID:15894607 |
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NCBI chr 3:76,441,621...76,492,782
Ensembl chr 3:76,424,469...76,492,782
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| G
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Dync2i2
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dynein 2 intermediate chain 2
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multiple interactions
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ISO
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Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to DYNC2I2 protein]
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CTD |
PMID:26598702 |
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NCBI chr 3:33,703,882...33,719,960
Ensembl chr 3:33,703,882...33,719,960
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Dyrk1a
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dual specificity tyrosine phosphorylation regulated kinase 1A
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increases response to substance
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ISO
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DYRK1A protein results in increased susceptibility to Arsenic Trioxide
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CTD |
PMID:20707922 |
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NCBI chr11:47,360,824...47,479,033
Ensembl chr11:47,360,850...47,479,033
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Dyrk1b
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dual specificity tyrosine phosphorylation regulated kinase 1B
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increases expression
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ISO
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Arsenic Trioxide results in increased expression of DYRK1B mRNA
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CTD |
PMID:15070760 |
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NCBI chr 1:92,606,743...92,624,089
Ensembl chr 1:92,607,303...92,614,744
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Dyrk2
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dual specificity tyrosine phosphorylation regulated kinase 2
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increases expression
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ISO
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Arsenic Trioxide results in increased expression of DYRK2 mRNA
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CTD |
PMID:20458559 |
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NCBI chr 7:56,235,276...56,265,741
Ensembl chr 7:56,235,276...56,265,942
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| G
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E2f1
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E2F transcription factor 1
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decreases expression affects methylation increases expression multiple interactions
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ISO
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Arsenic Trioxide results in decreased expression of E2F1 protein Arsenic Trioxide affects the methylation of E2F1 promoter Arsenic Trioxide results in increased expression of E2F1 mRNA Arsenic Trioxide inhibits the reaction [TP53 protein binds to E2F1 protein]; Arsenic Trioxide promotes the reaction [RB1 protein binds to E2F1 protein]; TP53 protein promotes the reaction [Arsenic Trioxide results in decreased expression of E2F1 protein]
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CTD |
PMID:20016248 PMID:24691991 PMID:25174355 PMID:25335113 PMID:26046465 PMID:34042274 More...
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NCBI chr 3:163,524,739...163,535,563
Ensembl chr 3:163,524,739...163,535,563
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| G
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E2f2
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E2F transcription factor 2
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increases expression
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ISO
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Arsenic Trioxide results in increased expression of E2F2 mRNA
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CTD |
PMID:17530438 |
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NCBI chr 5:153,682,789...153,706,087
Ensembl chr 5:153,682,789...153,706,087
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| G
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E2f3
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E2F transcription factor 3
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increases response to substance increases expression
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ISO
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E2F3 protein results in increased susceptibility to Arsenic Trioxide Arsenic Trioxide results in increased expression of E2F3 mRNA
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CTD |
PMID:20707922 PMID:20862710 |
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NCBI chr17:34,810,355...34,887,725
Ensembl chr17:34,809,998...34,887,725
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E2f4
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E2F transcription factor 4
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increases expression
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ISO
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Arsenic Trioxide results in increased expression of E2F4 mRNA
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CTD |
PMID:20458559 PMID:29633893 |
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NCBI chr19:50,084,335...50,091,731
Ensembl chr19:50,084,335...50,091,834
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E2f5
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E2F transcription factor 5
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decreases expression
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ISO
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Arsenic Trioxide results in decreased expression of E2F5 mRNA
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CTD |
PMID:17530438 PMID:27829220 |
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NCBI chr 2:88,718,567...88,734,143
Ensembl chr 2:88,718,567...88,734,143
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| G
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E2f6
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E2F transcription factor 6
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affects methylation
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ISO
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Arsenic Trioxide affects the methylation of E2F6 promoter
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CTD |
PMID:26046465 |
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NCBI chr 6:45,320,993...45,337,437
Ensembl chr 6:45,320,996...45,337,428
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E2f8
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E2F transcription factor 8
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decreases expression
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ISO
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Arsenic Trioxide results in decreased expression of E2F8 mRNA
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CTD |
PMID:26705709 |
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NCBI chr 1:107,701,985...107,720,538
Ensembl chr 1:107,701,985...107,720,009
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| G
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Ebna1bp2
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EBNA1 binding protein 2
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decreases expression
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ISO
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Arsenic Trioxide results in decreased expression of EBNA1BP2 mRNA
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CTD |
PMID:35676786 |
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NCBI chr 5:137,433,534...137,438,100
Ensembl chr 5:137,433,226...137,438,637
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| G
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Ebpl
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EBP like
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decreases expression
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ISO
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Arsenic Trioxide results in decreased expression of EBPL mRNA
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CTD |
PMID:39716349 |
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NCBI chr15:39,684,140...39,707,537
Ensembl chr15:39,684,140...39,707,537
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| G
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Ecd
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ecdysoneless cell cycle regulator
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decreases expression
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ISO
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Arsenic Trioxide results in decreased expression of ECD mRNA
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CTD |
PMID:15894607 |
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NCBI chr15:4,016,411...4,047,899
Ensembl chr15:4,016,403...4,047,897
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| G
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Ech1
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enoyl-CoA hydratase 1
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increases expression
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ISO
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Arsenic Trioxide results in increased expression of ECH1 protein
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CTD |
PMID:19364129 |
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NCBI chr 1:93,241,076...93,248,314
Ensembl chr 1:93,241,734...93,248,440
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Echs1
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enoyl-CoA hydratase, short chain 1
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increases expression
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ISO
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Arsenic Trioxide results in increased expression of ECHS1 protein
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CTD |
PMID:19364129 PMID:25419056 |
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NCBI chr 1:204,324,679...204,333,506
Ensembl chr 1:204,324,682...204,333,506
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Eci1
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enoyl-CoA delta isomerase 1
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decreases response to substance
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ISO
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ECI1 protein results in decreased susceptibility to Arsenic Trioxide
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CTD |
PMID:20707922 |
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NCBI chr10:13,961,250...13,974,595
Ensembl chr10:13,961,218...13,974,773
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Ecm1
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extracellular matrix protein 1
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increases expression
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ISO
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Arsenic Trioxide results in increased expression of ECM1 mRNA
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CTD |
PMID:20458559 |
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NCBI chr 2:185,976,439...185,981,656
Ensembl chr 2:185,976,440...185,981,606
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Ecpas
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Ecm29 proteasome adaptor and scaffold
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increases expression
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ISO
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Arsenic Trioxide results in increased expression of ECPAS mRNA
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CTD |
PMID:20458559 |
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NCBI chr 5:78,398,449...78,509,077
Ensembl chr 5:78,398,718...78,512,908
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| G
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Ecrg4
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ECRG4 augurin precursor
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multiple interactions decreases methylation decreases expression
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ISO
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[Arsenic Trioxide results in decreased methylation of ECRG4 promoter] which results in increased expression of ECRG4 mRNA Arsenic Trioxide results in decreased expression of ECRG4 mRNA
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CTD |
PMID:22325214 PMID:35676786 |
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NCBI chr 9:53,485,040...53,504,691
Ensembl chr 9:53,485,040...53,504,703
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| G
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Ecscr
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endothelial cell surface expressed chemotaxis and apoptosis regulator
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decreases expression
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ISO
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Arsenic Trioxide results in decreased expression of ECSCR mRNA
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CTD |
PMID:26705709 |
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NCBI chr18:27,583,791...27,593,184
Ensembl chr18:27,583,195...27,593,195
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| G
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Eda2r
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ectodysplasin A2 receptor
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increases expression multiple interactions
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ISO
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Arsenic Trioxide results in increased expression of EDA2R mRNA Metformin inhibits the reaction [Arsenic Trioxide results in increased expression of EDA2R mRNA]
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CTD |
PMID:29095437 |
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NCBI chr X:66,225,557...66,280,674
Ensembl chr X:66,236,111...66,280,663
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| G
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Edem1
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ER degradation enhancing alpha-mannosidase like protein 1
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multiple interactions increases expression
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ISO
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Arsenic Trioxide promotes the reaction [nilotinib results in increased expression of EDEM1 mRNA] Arsenic Trioxide results in increased expression of EDEM1 mRNA
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CTD |
PMID:23883479 |
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NCBI chr 4:143,350,989...143,385,693
Ensembl chr 4:143,353,624...143,388,060
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| G
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Edn1
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endothelin 1
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increases expression
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ISO
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Arsenic Trioxide results in increased expression of EDN1 mRNA
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CTD |
PMID:26705709 |
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NCBI chr17:22,660,799...22,666,687
Ensembl chr17:22,660,799...22,666,687
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| G
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Edn3
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endothelin 3
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decreases expression
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ISO
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Arsenic Trioxide results in decreased expression of EDN3 mRNA
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CTD |
PMID:35676786 |
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NCBI chr 3:183,980,458...184,004,958
Ensembl chr 3:183,980,668...184,005,329
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| G
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Ednrb
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endothelin receptor type B
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decreases expression increases expression
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ISO
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Arsenic Trioxide results in decreased expression of EDNRB mRNA Arsenic Trioxide results in increased expression of EDNRB mRNA alternative form
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CTD |
PMID:19128835 PMID:26705709 |
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NCBI chr15:87,055,490...87,086,765
Ensembl chr15:87,057,691...87,086,765
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| G
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Edrf1
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erythroid differentiation regulatory factor 1
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decreases expression
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ISO
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Arsenic Trioxide results in decreased expression of EDRF1 mRNA
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CTD |
PMID:27829220 |
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NCBI chr 1:197,869,873...197,908,693
Ensembl chr 1:197,870,962...197,908,731
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| G
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Eef1a1
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eukaryotic translation elongation factor 1 alpha 1
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multiple interactions decreases expression
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ISO
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[Tretinoin co-treated with Arsenic Trioxide] results in decreased expression of EEF1A1 protein Arsenic Trioxide results in decreased expression of EEF1A1 protein
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CTD |
PMID:15894607 PMID:25258189 |
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NCBI chr 8:88,221,839...88,225,688
Ensembl chr 8:88,221,843...88,225,072
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| G
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Eef1a2
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eukaryotic translation elongation factor 1 alpha 2
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decreases response to substance increases expression
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ISO
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EEF1A2 protein results in decreased susceptibility to Arsenic Trioxide Arsenic Trioxide results in increased expression of EEF1A2 mRNA
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CTD |
PMID:20707922 PMID:39716349 |
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NCBI chr 3:188,643,455...188,652,633
Ensembl chr 3:188,643,458...188,677,712
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| G
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Eef1akmt1
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EEF1A lysine methyltransferase 1
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multiple interactions
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ISO
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Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to EEF1AKMT1 protein]
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CTD |
PMID:26598702 |
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NCBI chr15:35,809,842...35,826,921
Ensembl chr15:35,809,842...35,827,129
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| G
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Eef1b2
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eukaryotic translation elongation factor 1 beta 2
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multiple interactions
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ISO
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[Tretinoin co-treated with Arsenic Trioxide] results in decreased expression of EEF1B2 protein; Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to EEF1B2 protein]
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CTD |
PMID:15894607 PMID:26598702 |
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NCBI chr 9:72,074,091...72,076,591
Ensembl chr 9:72,073,802...72,076,589
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| G
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Eef1d
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eukaryotic translation elongation factor 1 delta
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multiple interactions decreases expression
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ISO
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[Tretinoin co-treated with Arsenic Trioxide] results in decreased expression of EEF1D protein; Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to EEF1D protein] Arsenic Trioxide results in decreased expression of EEF1D protein
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CTD |
PMID:15894607 PMID:25419056 PMID:26598702 |
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NCBI chr 7:109,462,645...109,478,021
Ensembl chr 7:109,462,646...109,489,531
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| G
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Eef1e1
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eukaryotic translation elongation factor 1 epsilon 1
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multiple interactions
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ISO
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Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to EEF1E1 protein]
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CTD |
PMID:26598702 |
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NCBI chr17:26,354,247...26,364,953
Ensembl chr17:26,354,228...26,370,687
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| G
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Eef1g
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eukaryotic translation elongation factor 1 gamma
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decreases expression
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ISO
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Arsenic Trioxide results in decreased expression of EEF1G protein
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CTD |
PMID:15894607 |
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NCBI chr 1:215,289,815...215,300,421
Ensembl chr 1:215,277,860...215,301,479
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| G
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Eef2
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eukaryotic translation elongation factor 2
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decreases expression
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ISO
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Arsenic Trioxide results in decreased expression of EEF2 protein
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CTD |
PMID:19364129 |
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NCBI chr 7:9,183,836...9,196,255
Ensembl chr 7:9,183,961...9,189,544
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| G
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Eefsec
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eukaryotic elongation factor, selenocysteine-tRNA-specific
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decreases response to substance
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ISO
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EEFSEC gene mutant form results in decreased susceptibility to Arsenic Trioxide
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CTD |
PMID:30815697 |
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NCBI chr 4:122,276,907...122,473,049
Ensembl chr 4:122,263,535...122,473,049
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| G
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Efna1
|
ephrin A1
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increases expression
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ISO
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Arsenic Trioxide results in increased expression of EFNA1 mRNA
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CTD |
PMID:20458559 |
|
NCBI chr 2:176,979,434...176,988,675
Ensembl chr 2:176,979,434...176,988,726
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| G
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Egf
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epidermal growth factor
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increases expression multiple interactions
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ISO
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Arsenic Trioxide results in increased expression of EGF mRNA [Arsenic Trioxide co-treated with Pamidronate] promotes the reaction [EGF protein results in increased phosphorylation of EGFR protein]; Arsenic Trioxide promotes the reaction [EGF protein results in increased phosphorylation of EGFR protein]
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CTD |
PMID:15073043 PMID:26238599 PMID:32337366 |
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NCBI chr 2:220,893,660...220,976,331
Ensembl chr 2:220,893,660...220,976,297
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| G
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Egfl6
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EGF-like-domain, multiple 6
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decreases expression
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ISO
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Arsenic Trioxide results in decreased expression of EGFL6 mRNA
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CTD |
PMID:26705709 |
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NCBI chr X:31,515,752...31,573,699
Ensembl chr X:31,515,767...31,574,632
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| G
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Egfr
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epidermal growth factor receptor
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multiple interactions decreases expression increases phosphorylation affects response to substance increases expression
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ISO
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[Arsenic Trioxide co-treated with huachansu] results in decreased expression of EGFR protein Arsenic Trioxide results in decreased expression of EGFR protein Arsenic Trioxide results in increased phosphorylation of EGFR protein 4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of EGFR protein]; [Arsenic Trioxide co-treated with Pamidronate] promotes the reaction [EGF protein results in increased phosphorylation of EGFR protein]; Arsenic Trioxide promotes the reaction [EGF protein results in increased phosphorylation of EGFR protein]; Arsenic Trioxide promotes the reaction [EGFR protein mutant form binds to SQSTM1 protein]; Arsenic Trioxide results in decreased expression of and results in decreased phosphorylation of EGFR protein; Arsenic Trioxide results in increased phosphorylation of and results in increased activity of EGFR protein; bafilomycin A1 inhibits the reaction [Arsenic Trioxide results in decreased expression of EGFR protein]; Cycloheximide promotes the reaction [Arsenic Trioxide results in decreased expression of EGFR protein]; Erlotinib Hydrochloride inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of and results in increased activity of EGFR protein]; NCF2 mutant form inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of EGFR protein]; SQSTM1 protein affects the reaction [Arsenic Trioxide results in decreased expression of EGFR protein]; SQSTM1 protein inhibits the reaction [Arsenic Trioxide results in decreased expression of EGFR protein] Arsenic Trioxide results in decreased expression of EGFR mRNA; Arsenic Trioxide results in decreased expression of EGFR protein EGFR protein affects the susceptibility to Arsenic Trioxide; EGFR protein mutant form affects the susceptibility to Arsenic Trioxide Arsenic Trioxide results in increased expression of EGFR mRNA
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CTD |
PMID:15961274 PMID:20435036 PMID:21434348 PMID:22521957 PMID:22532027 PMID:23029451 PMID:23548265 PMID:29274334 PMID:29535630 PMID:30237564 PMID:32337366 More...
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NCBI chr14:95,378,626...95,551,358
Ensembl chr14:95,378,626...95,551,358
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| G
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Egr1
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early growth response 1
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affects methylation increases expression multiple interactions decreases expression affects expression
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ISO EXP
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Arsenic Trioxide affects the methylation of EGR1 promoter Arsenic Trioxide results in increased expression of EGR1 mRNA [Zidovudine co-treated with Arsenic Trioxide] results in increased expression of EGR1 mRNA Arsenic Trioxide results in decreased expression of EGR1 mRNA Arsenic Trioxide affects the expression of EGR1 mRNA pyrazolanthrone inhibits the reaction [Arsenic Trioxide results in increased expression of EGR1 mRNA]; Tretinoin promotes the reaction [Arsenic Trioxide results in increased expression of EGR1 mRNA]
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CTD |
PMID:12749819 PMID:15073043 PMID:15688020 PMID:20458559 PMID:22521957 PMID:22535156 PMID:25258189 PMID:26046465 PMID:29223816 PMID:29910624 More...
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NCBI chr18:26,737,078...26,740,877
Ensembl chr18:26,736,838...26,740,843
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| G
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Egr2
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early growth response 2
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multiple interactions decreases expression
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ISO
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Acetylcysteine inhibits the reaction [Arsenic Trioxide results in decreased expression of EGR2 mRNA]
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CTD |
PMID:19128835 PMID:19350554 |
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NCBI chr20:21,050,149...21,055,201
Ensembl chr20:21,050,149...21,057,748
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| G
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Egr3
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early growth response 3
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decreases expression
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ISO
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Arsenic Trioxide results in decreased expression of EGR3 mRNA
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CTD |
PMID:26705709 |
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NCBI chr15:51,560,482...51,565,778
Ensembl chr15:51,560,344...51,565,712
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| G
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Ehmt1
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euchromatic histone lysine methyltransferase 1
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increases expression
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ISO
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Arsenic Trioxide results in increased expression of EHMT1 mRNA
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CTD |
PMID:39716349 |
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NCBI chr 3:27,978,888...28,127,178
Ensembl chr 3:27,978,888...28,127,349
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| G
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Ehmt2
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euchromatic histone lysine methyltransferase 2
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decreases expression
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ISO
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Arsenic Trioxide results in decreased expression of EHMT2 mRNA
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CTD |
PMID:22521957 |
|
NCBI chr20:3,924,263...3,941,238
Ensembl chr20:3,924,263...3,941,384
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| G
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Eid1
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EP300 interacting inhibitor of differentiation 1
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increases expression
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ISO
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Arsenic Trioxide results in increased expression of EID1 mRNA
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CTD |
PMID:20458559 |
|
NCBI chr 3:133,376,389...133,378,108
Ensembl chr 3:133,370,474...133,378,434
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| G
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Eid3
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EP300 interacting inhibitor of differentiation 3
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increases expression
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ISO
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Arsenic Trioxide results in increased expression of EID3 mRNA
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CTD |
PMID:39716349 |
|
NCBI chr 7:22,747,645...22,748,967
Ensembl chr 7:22,747,656...22,749,177
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| G
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Eif2a
|
eukaryotic translation initiation factor 2A
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increases expression increases phosphorylation multiple interactions
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ISO
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Arsenic Trioxide results in increased expression of EIF2A mRNA Arsenic Trioxide results in increased phosphorylation of EIF2A protein 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of EIF2A protein]; [Arsenic Trioxide results in increased abundance of Reactive Oxygen Species] which results in increased phosphorylation of EIF2A protein; Thioctic Acid inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of EIF2A protein]
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CTD |
PMID:19176121 PMID:23892647 |
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NCBI chr 2:144,911,247...144,944,705
Ensembl chr 2:144,911,153...144,945,201
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| G
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Eif2ak1
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eukaryotic translation initiation factor 2 alpha kinase 1
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decreases expression
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ISO
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Arsenic Trioxide results in decreased expression of EIF2AK1 mRNA
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CTD |
PMID:39716349 |
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NCBI chr12:15,824,431...15,858,266
Ensembl chr12:15,825,124...15,858,281
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| G
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Eif2ak2
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eukaryotic translation initiation factor 2-alpha kinase 2
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multiple interactions increases phosphorylation
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ISO
|
Arsenic Trioxide promotes the reaction [MSI1 protein binds to EIF2AK2 protein modified form]; EIF2AK2 protein affects the reaction [Arsenic Trioxide promotes the reaction [MSI1 protein results in increased expression of KLF4 protein]]; EIF2AK2 protein affects the reaction [Arsenic Trioxide promotes the reaction [MSI1 protein results in increased expression of MYC protein]]; EIF2AK2 protein affects the reaction [Arsenic Trioxide promotes the reaction [MSI1 protein results in increased expression of POU5F1 protein]]; EIF2AK2 protein affects the reaction [Arsenic Trioxide promotes the reaction [MSI1 protein results in increased expression of SOX2 protein]]; EIF2AK2 protein affects the reaction [Arsenic Trioxide results in increased expression of KLF4 protein]; EIF2AK2 protein affects the reaction [Arsenic Trioxide results in increased expression of MYC protein]; EIF2AK2 protein affects the reaction [Arsenic Trioxide results in increased expression of POU5F1 protein]; EIF2AK2 protein affects the reaction [Arsenic Trioxide results in increased expression of SOX2 protein]; EIF2AK2 protein affects the reaction [MSI1 protein promotes the reaction [Arsenic Trioxide results in increased phosphorylation of EIF2S1 protein]]; EIF2S1 protein affects the reaction [MSI1 protein promotes the reaction [Arsenic Trioxide results in increased phosphorylation of EIF2AK2 protein]]; MSI1 protein promotes the reaction [Arsenic Trioxide results in increased phosphorylation of EIF2AK2 protein]
|
CTD |
PMID:29486283 |
|
NCBI chr 6:21,941,147...21,977,115
Ensembl chr 6:21,952,631...21,977,116
|
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| G
|
Eif2ak3
|
eukaryotic translation initiation factor 2 alpha kinase 3
|
increases expression multiple interactions increases phosphorylation
|
ISO EXP
|
Arsenic Trioxide results in increased expression of EIF2AK3 protein modified form Arsenic Trioxide results in increased expression of EIF2AK3 mRNA; Arsenic Trioxide results in increased expression of EIF2AK3 protein modified form 2-(4-chlorophenoxy)-N-(4-(2-(4-chlorophenoxy)acetamido)cyclohexyl)acetamide inhibits the reaction [Arsenic Trioxide results in increased expression of EIF2AK3 protein modified form]; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid inhibits the reaction [Arsenic Trioxide results in increased expression of EIF2AK3 protein modified form]; ATF4 protein promotes the reaction [Arsenic Trioxide results in increased expression of EIF2AK3 protein modified form] Arsenic Trioxide results in increased phosphorylation of EIF2AK3 protein sulforaphane promotes the reaction [Arsenic Trioxide results in increased expression of EIF2AK3 protein modified form]
|
CTD |
PMID:17963750 PMID:22922937 PMID:27638049 PMID:29111283 |
|
NCBI chr 4:104,363,838...104,425,271
Ensembl chr 4:104,363,833...104,425,268
|
|
| G
|
Eif2s1
|
eukaryotic translation initiation factor 2 subunit alpha
|
multiple interactions increases phosphorylation increases expression
|
ISO
|
4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of EIF2S1 protein]; 4-phenylbutyric acid inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of EIF2S1 protein] Arsenic Trioxide results in increased expression of EIF2S1 protein modified form 7-methyl-5-(1-((3-(trifluoromethyl)phenyl)acetyl)-2,3-dihydro-1H-indol-5-yl)-7H-pyrrolo(2,3-d)pyrimidin-4-amine inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of EIF2S1 protein]; Arsenic Trioxide promotes the reaction [MSI1 protein binds to EIF2S1 protein modified form]; EIF2AK2 protein affects the reaction [MSI1 protein promotes the reaction [Arsenic Trioxide results in increased phosphorylation of EIF2S1 protein]]; EIF2S1 protein affects the reaction [Arsenic Trioxide promotes the reaction [MSI1 protein results in increased expression of KLF4 protein]]; EIF2S1 protein affects the reaction [Arsenic Trioxide promotes the reaction [MSI1 protein results in increased expression of MYC protein]]; EIF2S1 protein affects the reaction [Arsenic Trioxide promotes the reaction [MSI1 protein results in increased expression of POU5F1 protein]]; EIF2S1 protein affects the reaction [Arsenic Trioxide promotes the reaction [MSI1 protein results in increased expression of SOX2 protein]]; EIF2S1 protein affects the reaction [MSI1 protein promotes the reaction [Arsenic Trioxide results in increased phosphorylation of EIF2AK2 protein]]; MSI1 protein promotes the reaction [Arsenic Trioxide results in increased phosphorylation of EIF2S1 protein]; sulforaphane promotes the reaction [Arsenic Trioxide results in increased expression of EIF2S1 protein modified form]
|
CTD |
PMID:22922937 PMID:25258189 PMID:27638049 PMID:29486283 PMID:34560123 |
|
NCBI chr 6:103,405,880...103,430,549
Ensembl chr 6:103,405,788...103,431,649
|
|
| G
|
Eif2s3y
|
eukaryotic translation initiation factor 2, subunit 3, structural gene Y-linked
|
multiple interactions
|
ISO
|
[Arsenic Trioxide co-treated with Tretinoin] results in decreased expression of EIF2S3B mRNA
|
CTD |
PMID:38179723 |
|
NCBI chr Y:944,653...964,303
Ensembl chr Y:944,618...964,778
|
|
| G
|
Eif3c
|
eukaryotic translation initiation factor 3, subunit C
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of EIF3C mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 1:190,565,183...190,583,067
Ensembl chr 1:190,565,184...190,583,067
|
|
| G
|
Eif3f
|
eukaryotic translation initiation factor 3, subunit F
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of EIF3F mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 1:172,369,062...172,378,043
Ensembl chr 1:172,369,062...172,378,041
|
|
| G
|
Eif3g
|
eukaryotic translation initiation factor 3, subunit G
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of EIF3G protein
|
CTD |
PMID:19364129 |
|
NCBI chr 8:27,705,914...27,709,946
Ensembl chr 8:27,705,915...27,709,987
|
|
| G
|
Eif3i
|
eukaryotic translation initiation factor 3, subunit I
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of EIF3I protein
|
CTD |
PMID:19364129 |
|
NCBI chr 5:147,219,457...147,226,910
Ensembl chr 5:147,219,366...147,241,232
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|
| G
|
Eif3m
|
eukaryotic translation initiation factor 3, subunit M
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of EIF3M mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 3:111,879,589...111,897,193
Ensembl chr 3:111,870,925...111,897,193
|
|
| G
|
Eif4a1
|
eukaryotic translation initiation factor 4A1
|
multiple interactions
|
ISO
|
[Tretinoin co-treated with Arsenic Trioxide] results in decreased expression of EIF4A1 protein
|
CTD |
PMID:15894607 |
|
NCBI chr10:54,883,093...54,888,602
Ensembl chr10:54,883,093...54,888,602
|
|
| G
|
Eif4a3
|
eukaryotic translation initiation factor 4A3
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of EIF4A3 protein
|
CTD |
PMID:19364129 |
|
NCBI chr10:105,047,567...105,057,561
Ensembl chr10:105,047,568...105,058,207
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|
| G
|
Eif4b
|
eukaryotic translation initiation factor 4B
|
decreases expression multiple interactions
|
ISO
|
Arsenic Trioxide results in decreased expression of EIF4B mRNA Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to EIF4B protein]
|
CTD |
PMID:23911876 PMID:26598702 |
|
NCBI chr 7:135,085,259...135,107,054
Ensembl chr 7:135,085,066...135,107,064
|
|
| G
|
Eif4e
|
eukaryotic translation initiation factor 4E
|
multiple interactions affects expression increases phosphorylation
|
ISO
|
[Arsenic Trioxide results in increased phosphorylation of and results in increased activity of MKNK1 protein] which results in increased phosphorylation of EIF4E protein; CGP 57380 inhibits the reaction [[Arsenic Trioxide results in increased phosphorylation of and results in increased activity of MKNK1 protein] which results in increased phosphorylation of EIF4E protein]; CGP 57380 inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of and results in increased activity of EIF4E protein]; CGP 57380 inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of EIF4E protein]; MAPK14 protein promotes the reaction [Arsenic Trioxide results in increased phosphorylation of and results in increased activity of EIF4E protein]; MKNK1 protein affects the reaction [Arsenic Trioxide results in increased phosphorylation of EIF4E protein]; MKNK1 protein promotes the reaction [Arsenic Trioxide results in increased phosphorylation of and results in increased activity of EIF4E protein]; MKNK2 protein promotes the reaction [Arsenic Trioxide results in increased phosphorylation of and results in increased activity of EIF4E protein]; U 0126 inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of and results in increased activity of EIF4E protein] Arsenic Trioxide affects the expression of EIF4E mRNA
|
CTD |
PMID:18299328 PMID:20458559 PMID:29042487 |
|
NCBI chr 2:229,736,309...229,772,628
Ensembl chr 2:229,739,897...229,774,105
|
|
| G
|
Eif4e1b
|
eukaryotic translation initiation factor 4E family member 1B
|
multiple interactions
|
ISO
|
[Arsenic Trioxide co-treated with apatinib] results in decreased expression of EIF4E1B mRNA
|
CTD |
PMID:39223679 |
|
NCBI chr17:9,835,883...9,868,781
Ensembl chr17:9,836,362...9,860,681
|
|
| G
|
Eif4e3
|
eukaryotic translation initiation factor 4E family member 3
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of EIF4E3 mRNA
|
CTD |
PMID:27829220 |
|
NCBI chr 4:133,709,802...133,858,398
Ensembl chr 4:133,625,768...133,885,647
|
|
| G
|
Eif4ebp1
|
eukaryotic translation initiation factor 4E binding protein 1
|
multiple interactions increases phosphorylation decreases phosphorylation
|
ISO
|
Arsenic Trioxide inhibits the reaction [Sorafenib results in increased phosphorylation of EIF4EBP1 protein] Arsenic Trioxide results in increased phosphorylation of EIF4EBP1 protein Arsenic Trioxide results in decreased phosphorylation of EIF4EBP1 protein
|
CTD |
PMID:18048359 PMID:25416439 |
|
NCBI chr16:71,495,457...71,508,845
Ensembl chr16:71,487,930...71,508,874
|
|
| G
|
Eif4g1
|
eukaryotic translation initiation factor 4 gamma 1
|
increases expression multiple interactions decreases expression
|
ISO
|
Arsenic Trioxide results in increased expression of EIF4G1 mRNA [Tretinoin co-treated with Arsenic Trioxide] results in increased expression of EIF4G1 mRNA Arsenic Trioxide results in decreased expression of EIF4G1 mRNA
|
CTD |
PMID:15894607 PMID:23911876 |
|
NCBI chr11:93,726,322...93,746,387
Ensembl chr11:93,726,322...93,746,367
|
|
| G
|
Eif4g2
|
eukaryotic translation initiation factor 4, gamma 2
|
increases cleavage
|
ISO
|
Arsenic Trioxide results in increased cleavage of EIF4G2 protein
|
CTD |
PMID:18491231 |
|
NCBI chr 1:174,616,102...174,628,252
Ensembl chr 1:174,616,103...174,628,252
|
|
| G
|
Eif5
|
eukaryotic translation initiation factor 5
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of EIF5 mRNA; Arsenic Trioxide results in increased expression of EIF5 protein
|
CTD |
PMID:20458559 PMID:25419056 |
|
NCBI chr 6:136,410,333...136,418,827
Ensembl chr 6:136,407,440...136,418,821
|
|
| G
|
Eif5a
|
eukaryotic translation initiation factor 5A
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of EIF5A protein
|
CTD |
PMID:25419056 |
|
NCBI chr10:55,138,821...55,143,272
Ensembl chr10:55,138,823...55,143,330
|
|
| G
|
Eif5a2
|
eukaryotic translation initiation factor 5A2
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of EIF5A2 mRNA
|
CTD |
PMID:30983542 |
|
NCBI chr 2:113,656,748...113,674,598
Ensembl chr 2:113,657,797...113,674,594
|
|
| G
|
Elac2
|
elaC ribonuclease Z 2
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of ELAC2 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr10:50,131,449...50,154,755
Ensembl chr10:50,131,521...50,155,069
|
|
| G
|
Elapor2
|
endosome-lysosome associated apoptosis and autophagy regulator family member 2
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of ELAPOR2 mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr 4:25,565,298...25,760,684
Ensembl chr 4:25,568,122...25,760,684
|
|
| G
|
Elavl1
|
ELAV like RNA binding protein 1
|
multiple interactions
|
ISO
|
[Arsenic Trioxide promotes the reaction [ELAVL1 protein binds to TGIF1 promoter]] which results in decreased degradation of TGIF1 promoter; Arsenic Trioxide promotes the reaction [ELAVL1 protein binds to TGIF1 promoter]
|
CTD |
PMID:21649584 |
|
NCBI chr12:7,441,699...7,482,625
Ensembl chr12:7,441,699...7,482,631
|
|
| G
|
Elavl4
|
ELAV like RNA binding protein 4
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of ELAVL4 mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr 5:130,285,418...130,429,106
Ensembl chr 5:130,285,418...130,429,096
|
|
| G
|
Elf1
|
E74 like ETS transcription factor 1
|
affects methylation
|
ISO
|
Arsenic Trioxide affects the methylation of ELF1 promoter
|
CTD |
PMID:26046465 |
|
NCBI chr15:61,354,026...61,395,762
Ensembl chr15:61,330,877...61,395,758
|
|
| G
|
Elf3
|
E74 like ETS transcription factor 3
|
decreases response to substance
|
ISO
|
ELF3 protein results in decreased susceptibility to Arsenic Trioxide
|
CTD |
PMID:20707922 |
|
NCBI chr13:49,242,265...49,247,102
Ensembl chr13:49,242,267...49,247,380
|
|
| G
|
Elk1
|
ETS transcription factor ELK1
|
multiple interactions increases phosphorylation
|
ISO
|
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of ELK1 protein]
|
CTD |
PMID:32683294 |
|
NCBI chr X:3,692,367...3,709,252
Ensembl chr X:3,693,293...3,709,249
|
|
| G
|
Elk4
|
ETS transcription factor ELK4
|
decreases methylation
|
ISO
|
Arsenic Trioxide results in decreased methylation of ELK4 promoter
|
CTD |
PMID:26046465 |
|
NCBI chr13:46,004,145...46,027,206
Ensembl chr13:46,004,182...46,027,199
|
|
| G
|
Ell3
|
elongation factor for RNA polymerase II 3
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of ELL3 mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr 3:128,866,755...128,870,896
Ensembl chr 3:128,864,777...128,870,852
|
|
| G
|
Elmo1
|
engulfment and cell motility 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of ELMO1 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr17:48,982,188...49,518,525
Ensembl chr17:48,982,188...49,518,159
|
|
| G
|
Elmod1
|
ELMO domain containing 1
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of ELMOD1 mRNA
|
CTD |
PMID:26705709 |
|
NCBI chr 8:63,194,539...63,251,526
Ensembl chr 8:63,137,295...63,251,322
|
|
| G
|
Elovl2
|
ELOVL fatty acid elongase 2
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of ELOVL2 mRNA
|
CTD |
PMID:26705709 |
|
NCBI chr17:23,750,350...23,790,601
Ensembl chr17:23,750,350...23,790,601
|
|
| G
|
Elovl5
|
ELOVL fatty acid elongase 5
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of ELOVL5 mRNA
|
CTD |
PMID:19128835 |
|
NCBI chr 8:87,671,164...87,737,618
Ensembl chr 8:87,671,159...87,737,616
|
|
| G
|
Elp5
|
elongator acetyltransferase complex subunit 5
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of ELP5 mRNA
|
CTD |
PMID:22521957 |
|
NCBI chr10:55,191,223...55,202,949
Ensembl chr10:55,191,227...55,203,617
|
|
| G
|
Elp6
|
elongator acetyltransferase complex subunit 6
|
multiple interactions decreases expression
|
ISO
|
[Arsenic Trioxide co-treated with Ascorbic Acid] results in decreased expression of ELP6 mRNA Arsenic Trioxide results in decreased expression of ELP6 mRNA
|
CTD |
PMID:25555879 |
|
NCBI chr 8:119,158,380...119,173,483
Ensembl chr 8:119,158,396...119,174,244
|
|
| G
|
Emcn
|
endomucin
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of EMCN mRNA
|
CTD |
PMID:26705709 |
|
NCBI chr 2:228,564,445...228,644,370
Ensembl chr 2:228,564,430...228,645,155
|
|
| G
|
Emd
|
emerin
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of EMD mRNA
|
CTD |
PMID:25258189 |
|
NCBI chr X:157,190,438...157,193,479
Ensembl chr X:157,189,819...157,197,095
|
|
| G
|
Eml1
|
EMAP like 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of EML1 mRNA
|
CTD |
PMID:35676786 |
|
NCBI chr 6:133,048,271...133,221,642
Ensembl chr 6:133,048,427...133,221,642
|
|
| G
|
Eml2
|
EMAP like 2
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of EML2 protein
|
CTD |
PMID:25419056 |
|
NCBI chr 1:87,955,924...87,987,366
Ensembl chr 1:87,955,606...87,987,366
|
|
| G
|
Eml4
|
EMAP like 4
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of EML4 protein
|
CTD |
PMID:25419056 |
|
NCBI chr 6:16,972,054...17,087,365
Ensembl chr 6:16,972,075...17,087,439
|
|
| G
|
Emp2
|
epithelial membrane protein 2
|
affects expression
|
ISO
|
Arsenic Trioxide affects the expression of EMP2 mRNA
|
CTD |
PMID:28786057 |
|
NCBI chr10:5,866,869...5,901,533
Ensembl chr10:5,866,922...5,901,532
|
|
| G
|
Emp3
|
epithelial membrane protein 3
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of EMP3 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 1:105,525,086...105,528,370
Ensembl chr 1:105,525,088...105,528,265
|
|
| G
|
Enah
|
ENAH, actin regulator
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of ENAH mRNA
|
CTD |
PMID:22521957 |
|
NCBI chr13:96,149,437...96,269,841
Ensembl chr13:96,149,437...96,269,796
|
|
| G
|
Enc1
|
ectodermal-neural cortex 1
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of ENC1 mRNA
|
CTD |
PMID:22521957 |
|
NCBI chr 2:30,285,274...30,297,194
Ensembl chr 2:30,283,736...30,315,721
|
|
| G
|
Eng
|
endoglin
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of ENG mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 3:36,332,190...36,370,324
Ensembl chr 3:36,326,202...36,370,933
|
|
| G
|
Eno1
|
enolase 1
|
multiple interactions decreases expression
|
ISO
|
[Ascorbic Acid co-treated with Arsenic Trioxide] results in decreased expression of ENO1 protein; Arsenic Trioxide promotes the reaction [Ascorbic Acid results in decreased expression of ENO1 mRNA]; Arsenic Trioxide promotes the reaction [Ascorbic Acid results in decreased expression of ENO1 protein]; Ascorbic Acid promotes the reaction [Arsenic Trioxide results in decreased expression of ENO1 mRNA]; Ascorbic Acid promotes the reaction [Arsenic Trioxide results in decreased expression of ENO1 protein] Arsenic Trioxide results in decreased expression of ENO1 mRNA; Arsenic Trioxide results in decreased expression of ENO1 protein
|
CTD |
PMID:38160894 |
|
NCBI chr 5:166,002,867...166,014,252
Ensembl chr 3:77,946,261...77,986,003 Ensembl chr 5:77,946,261...77,986,003
|
|
| G
|
Enox2
|
ecto-NOX disulfide-thiol exchanger 2
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of ENOX2 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr X:133,148,813...133,470,914
Ensembl chr X:133,148,813...133,470,891
|
|
| G
|
Enpp2
|
ectonucleotide pyrophosphatase/phosphodiesterase 2
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of ENPP2 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 7:88,092,140...88,214,758
Ensembl chr 7:88,092,140...88,214,957
|
|
| G
|
Ep300
|
E1A binding protein p300
|
increases expression increases activity multiple interactions
|
ISO
|
Arsenic Trioxide results in increased expression of EP300 mRNA Arsenic Trioxide results in increased activity of EP300 protein Arsenic Trioxide promotes the reaction [EP300 protein binds to and results in increased acetylation of TP73 protein]
|
CTD |
PMID:15031205 PMID:20458559 |
|
NCBI chr 7:114,987,857...115,058,652
Ensembl chr 7:114,946,982...115,058,574
|
|
| G
|
Epb41
|
erythrocyte membrane protein band 4.1
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of EPB41 mRNA
|
CTD |
PMID:35676786 |
|
NCBI chr 5:149,394,080...149,548,178
Ensembl chr 5:149,394,096...149,543,540
|
|
| G
|
Epb41l1
|
erythrocyte membrane protein band 4.1-like 1
|
decreases response to substance increases expression
|
ISO
|
EPB41L1 protein results in decreased susceptibility to Arsenic Trioxide Arsenic Trioxide results in increased expression of EPB41L1 protein
|
CTD |
PMID:20707922 PMID:30093655 |
|
NCBI chr 3:165,389,295...165,512,821
Ensembl chr 3:165,389,293...165,510,498
|
|
| G
|
Epb41l2
|
erythrocyte membrane protein band 4.1-like 2
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of EPB41L2 mRNA
|
CTD |
PMID:15761015 |
|
NCBI chr 1:21,682,336...21,857,106
Ensembl chr 1:21,682,335...21,857,105
|
|
| G
|
Epb41l4b
|
erythrocyte membrane protein band 4.1 like 4B
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of EPB41L4B mRNA
|
CTD |
PMID:22521957 |
|
NCBI chr 5:76,486,886...76,647,752
Ensembl chr 5:76,486,902...76,647,752
|
|
| G
|
Epb41l5
|
erythrocyte membrane protein band 4.1 like 5
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of EPB41L5 mRNA
|
CTD |
PMID:35676786 |
|
NCBI chr13:33,221,705...33,321,400
Ensembl chr13:33,223,589...33,321,133
|
|
| G
|
Epcam
|
epithelial cell adhesion molecule
|
decreases response to substance
|
ISO
|
EPCAM protein results in decreased susceptibility to Arsenic Trioxide
|
CTD |
PMID:20707922 |
|
NCBI chr 6:12,633,715...12,649,678
Ensembl chr 6:12,631,611...12,649,702
|
|
| G
|
Ephb4
|
EPH receptor B4
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of EPHB4 mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr12:24,963,174...24,988,473
Ensembl chr12:24,963,174...24,988,388
|
|
| G
|
Ephx1
|
epoxide hydrolase 1
|
decreases expression increases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of EPHX1 mRNA Arsenic Trioxide results in increased expression of EPHX1 mRNA
|
CTD |
PMID:17547211 PMID:39716349 |
|
NCBI chr13:95,246,079...95,275,852
Ensembl chr13:95,246,080...95,321,981
|
|
| G
|
Ephx2
|
epoxide hydrolase 2
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of EPHX2 mRNA
|
CTD |
PMID:17530438 |
|
NCBI chr15:44,465,447...44,503,157
Ensembl chr15:44,465,448...44,503,160
|
|
| G
|
Epor
|
erythropoietin receptor
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of EPOR protein
|
CTD |
PMID:16360329 |
|
NCBI chr 8:28,765,738...28,770,371
Ensembl chr 8:28,765,746...28,770,322
|
|
| G
|
Epsti1
|
epithelial stromal interaction 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of EPSTI1 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr15:59,692,712...59,791,376
Ensembl chr15:59,693,142...59,791,380
|
|
| G
|
Epx
|
eosinophil peroxidase
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of EPX mRNA
|
CTD |
PMID:15070760 PMID:15761015 |
|
NCBI chr10:73,164,096...73,175,180
Ensembl chr10:73,164,096...73,175,180
|
|
| G
|
Epyc
|
epiphycan
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of EPYC mRNA
|
CTD |
PMID:26705709 |
|
NCBI chr 7:34,323,332...34,360,845
Ensembl chr 7:34,323,273...34,361,032
|
|
| G
|
Eqtn
|
equatorin
|
multiple interactions decreases expression
|
ISO
|
Metformin inhibits the reaction [Arsenic Trioxide results in decreased expression of EQTN mRNA]
|
CTD |
PMID:29095437 |
|
NCBI chr 5:114,851,981...114,880,683
Ensembl chr 5:114,862,608...114,878,954
|
|
| G
|
Erbb2
|
erb-b2 receptor tyrosine kinase 2
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of ERBB2 gene mutant form
|
CTD |
PMID:38746032 |
|
NCBI chr10:83,907,491...83,931,365
Ensembl chr10:83,907,460...83,931,481
|
|
| G
|
Erbb4
|
erb-b2 receptor tyrosine kinase 4
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of ERBB4 gene mutant form; Arsenic Trioxide results in increased expression of ERBB4 mRNA
|
CTD |
PMID:19769630 PMID:20458559 PMID:38746032 |
|
NCBI chr 9:76,973,386...78,045,633
Ensembl chr 9:76,973,227...78,045,772
|
|
| G
|
Erc1
|
ELKS/RAB6-interacting/CAST family member 1
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of ERC1 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 4:154,435,936...154,727,987
Ensembl chr 4:154,435,944...154,727,987
|
|
| G
|
Erc2
|
ELKS/RAB6-interacting/CAST family member 2
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of ERC2 mRNA
|
CTD |
PMID:15761015 |
|
NCBI chr16:2,819,399...3,680,258
Ensembl chr16:2,819,512...3,680,258
|
|
| G
|
Ercc2
|
ERCC excision repair 2, TFIIH core complex helicase subunit
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of ERCC2 mRNA
|
CTD |
PMID:22521957 |
|
NCBI chr 1:88,161,342...88,175,102
Ensembl chr 1:88,160,988...88,175,102
|
|
| G
|
Ercc4
|
ERCC excision repair 4, endonuclease catalytic subunit
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of ERCC4 mRNA
|
CTD |
PMID:17530438 |
|
NCBI chr10:2,926,085...2,958,176
Ensembl chr10:2,920,455...2,955,539
|
|
| G
|
Ercc5
|
ERCC excision repair 5, endonuclease
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of ERCC5 mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr 9:53,801,471...53,846,611
Ensembl chr 9:53,801,714...53,875,084
|
|
| G
|
Ercc6
|
ERCC excision repair 6, chromatin remodeling factor
|
affects response to substance
|
ISO
|
ERCC6 protein affects the susceptibility to Arsenic Trioxide
|
CTD |
PMID:22280988 |
|
NCBI chr16:7,771,311...7,841,895
Ensembl chr16:7,771,581...7,841,895
|
|
| G
|
Ercc8
|
ERCC excision repair 8, CSA ubiquitin ligase complex subunit
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of ERCC8 mRNA
|
CTD |
PMID:22521957 |
|
NCBI chr 2:41,380,901...41,418,294
Ensembl chr 2:41,380,901...41,418,294
|
|
| G
|
Erh
|
ERH, mRNA splicing and mitosis factor
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of ERH protein
|
CTD |
PMID:25419056 |
|
NCBI chr 6:106,012,255...106,022,521
Ensembl chr 6:106,012,255...106,022,623
|
|
| G
|
Ern1
|
endoplasmic reticulum to nucleus signaling 1
|
multiple interactions increases expression increases phosphorylation
|
EXP ISO
|
Taurine inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of ERN1 protein] Arsenic Trioxide results in increased expression of ERN1 mRNA; Arsenic Trioxide results in increased expression of ERN1 protein
|
CTD |
PMID:17963750 PMID:19176121 PMID:22521957 PMID:25449439 PMID:30660605 PMID:34560123 PMID:39716349 More...
|
|
NCBI chr10:91,826,663...91,920,976
Ensembl chr10:91,830,428...91,920,791
|
|
| G
|
Ern2
|
endoplasmic reticulum to nucleus signaling 2
|
multiple interactions increases expression
|
ISO
|
[Arsenic Trioxide co-treated with antimony trichloride] results in increased expression of ERN2 mRNA Arsenic Trioxide results in increased expression of ERN2 mRNA
|
CTD |
PMID:34091186 |
|
NCBI chr 1:186,153,115...186,174,521
Ensembl chr 1:186,157,691...186,174,521
|
|
| G
|
Errfi1
|
ERBB receptor feedback inhibitor 1
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of ERRFI1 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 5:166,606,841...166,620,124
Ensembl chr 5:166,606,834...166,620,432
|
|
| G
|
Esd
|
esterase D
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of ESD mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr15:56,453,082...56,472,582
Ensembl chr15:56,453,044...56,473,508
|
|
| G
|
Esr1
|
estrogen receptor 1
|
decreases methylation increases expression multiple interactions decreases expression
|
ISO
|
Arsenic Trioxide results in decreased methylation of ESR1 promoter [Arsenic Trioxide results in increased expression of ESR1 protein] which results in increased expression of GREB1 mRNA; [Arsenic Trioxide results in increased expression of ESR1 protein] which results in increased expression of TFF1 mRNA; Arsenic Trioxide results in increased expression of ESR1 mRNA; Arsenic Trioxide results in increased expression of ESR1 protein [Arsenic Trioxide results in decreased methylation of ESR1 promoter] which results in increased expression of ESR1 mRNA; [Arsenic Trioxide results in increased expression of ESR1 protein] which results in increased susceptibility to Estradiol; afimoxifene inhibits the reaction [[Arsenic Trioxide results in increased expression of ESR1 protein] which results in increased expression of GREB1 mRNA]; afimoxifene inhibits the reaction [[Arsenic Trioxide results in increased expression of ESR1 protein] which results in increased expression of TFF1 mRNA]; Arsenic Trioxide inhibits the reaction [DNMT1 protein binds to ESR1 promoter]; Arsenic Trioxide promotes the reaction [Estradiol results in decreased expression of ESR1 mRNA]; Arsenic Trioxide promotes the reaction [Estradiol results in decreased expression of ESR1 protein]; Estradiol promotes the reaction [Arsenic Trioxide results in decreased expression of ESR1 mRNA]; Estradiol promotes the reaction [Arsenic Trioxide results in decreased expression of ESR1 protein]; Fulvestrant inhibits the reaction [[Arsenic Trioxide results in increased expression of ESR1 protein] which results in increased expression of GREB1 mRNA]; Fulvestrant inhibits the reaction [[Arsenic Trioxide results in increased expression of ESR1 protein] which results in increased expression of TFF1 mRNA]; S-Adenosylmethionine inhibits the reaction [[Arsenic Trioxide results in increased expression of ESR1 protein] which results in increased expression of GREB1 mRNA]; S-Adenosylmethionine inhibits the reaction [[Arsenic Trioxide results in increased expression of ESR1 protein] which results in increased expression of TFF1 mRNA]; S-Adenosylmethionine inhibits the reaction [Arsenic Trioxide inhibits the reaction [DNMT1 protein binds to ESR1 promoter]]; S-Adenosylmethionine inhibits the reaction [Arsenic Trioxide results in decreased methylation of ESR1 promoter]; S-Adenosylmethionine inhibits the reaction [Arsenic Trioxide results in increased expression of ESR1 mRNA]; S-Adenosylmethionine inhibits the reaction [Arsenic Trioxide results in increased expression of ESR1 protein] Arsenic Trioxide results in decreased expression of ESR1 mRNA; Arsenic Trioxide results in decreased expression of ESR1 protein [Arsenic Trioxide co-treated with Tamoxifen] results in decreased methylation of ESR1 gene; [Arsenic Trioxide co-treated with Tamoxifen] results in increased expression of ESR1 mRNA; [Arsenic Trioxide co-treated with Tamoxifen] results in increased expression of ESR1 protein Arsenic Trioxide results in decreased methylation of ESR1 gene; Arsenic Trioxide results in decreased methylation of ESR1 promoter
|
CTD |
PMID:12014631 PMID:15073043 PMID:15283693 PMID:19088370 PMID:20458559 PMID:21687957 PMID:22558281 PMID:23159075 PMID:34050381 More...
|
|
NCBI chr 1:43,511,685...43,904,454
Ensembl chr 1:43,644,392...43,900,354
|
|
| G
|
Esr2
|
estrogen receptor 2
|
multiple interactions
|
ISO
|
[Arsenic Trioxide co-treated with Bortezomib] results in decreased expression of ESR2 mRNA
|
CTD |
PMID:25913414 |
|
NCBI chr 6:100,589,553...100,645,240
Ensembl chr 6:100,545,206...100,644,709
|
|
| G
|
Esrp1
|
epithelial splicing regulatory protein 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of ESRP1 mRNA
|
CTD |
PMID:27829220 |
|
NCBI chr 5:29,224,831...29,279,381
Ensembl chr 5:29,225,360...29,279,278
|
|
| G
|
Esrra
|
estrogen related receptor, alpha
|
decreases expression multiple interactions
|
EXP
|
Arsenic Trioxide results in decreased expression of ESRRA mRNA Nicorandil inhibits the reaction [Arsenic Trioxide results in decreased expression of ESRRA mRNA]
|
CTD |
PMID:38741475 |
|
NCBI chr 1:213,533,309...213,543,432
Ensembl chr 1:213,533,310...213,543,811
|
|
| G
|
Esrrg
|
estrogen-related receptor gamma
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of ESRRG mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr13:101,699,043...102,316,877
Ensembl chr13:101,889,706...102,316,877
|
|
| G
|
Esx1
|
ESX homeobox 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of ESX1 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr X:105,241,568...105,246,733
|
|
| G
|
Esyt1
|
extended synaptotagmin 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of ESYT1 protein
|
CTD |
PMID:25419056 |
|
NCBI chr 7:1,513,381...1,530,836
Ensembl chr 7:1,513,381...1,530,732
|
|
| G
|
Etfa
|
electron transfer flavoprotein subunit alpha
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of ETFA mRNA; Arsenic Trioxide results in increased expression of ETFA protein
|
CTD |
PMID:22521957 PMID:25419056 PMID:35676786 |
|
NCBI chr 8:64,731,192...64,787,965
Ensembl chr 8:64,731,193...64,788,080
|
|
| G
|
Etfb
|
electron transfer flavoprotein subunit beta
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of ETFB protein
|
CTD |
PMID:25419056 |
|
NCBI chr 1:102,988,499...103,002,663
Ensembl chr 1:102,988,499...103,002,659
|
|
| G
|
Ethe1
|
ETHE1, persulfide dioxygenase
|
decreases expression decreases response to substance
|
ISO
|
Arsenic Trioxide results in decreased expression of ETHE1 mRNA ETHE1 protein results in decreased susceptibility to Arsenic Trioxide
|
CTD |
PMID:20707922 PMID:27829220 |
|
NCBI chr 1:89,311,948...89,327,000
Ensembl chr 1:89,311,934...89,326,998
|
|
| G
|
Ets1
|
ETS proto-oncogene 1, transcription factor
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of ETS1 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 8:39,303,936...39,426,022
Ensembl chr 8:39,303,925...39,426,021
|
|
| G
|
Ets2
|
ETS proto-oncogene 2, transcription factor
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of ETS2 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr11:48,491,057...48,507,843
Ensembl chr11:48,491,394...48,507,842
|
|
| G
|
Etv3
|
ETS variant transcription factor 3
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of ETV3 mRNA
|
CTD |
PMID:25258189 |
|
NCBI chr 2:175,263,389...175,278,217
Ensembl chr 2:175,263,459...175,278,208
|
|
| G
|
Etv4
|
ETS variant transcription factor 4
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of ETV4 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr10:87,206,977...87,222,202
Ensembl chr10:87,206,977...87,222,318
|
|
| G
|
Evi2a
|
ecotropic viral integration site 2A
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of EVI2A mRNA
|
CTD |
PMID:24356939 |
|
NCBI chr10:64,983,727...64,987,627
Ensembl chr10:64,983,705...64,999,516
|
|
| G
|
Evl
|
Enah/Vasp-like
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of EVL mRNA
|
CTD |
PMID:15725085 |
|
NCBI chr 6:133,238,547...133,358,730
Ensembl chr 6:133,238,547...133,358,729
|
|
| G
|
Evpl
|
envoplakin
|
decreases response to substance
|
ISO
|
EVPL protein results in decreased susceptibility to Arsenic Trioxide
|
CTD |
PMID:20707922 |
|
NCBI chr10:101,957,107...101,973,656
Ensembl chr10:101,941,064...101,973,656
|
|
| G
|
Ewsr1
|
EWS RNA-binding protein 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of EWSR1 protein
|
CTD |
PMID:25419056 |
|
NCBI chr14:84,179,413...84,208,149
Ensembl chr14:84,179,618...84,208,095
|
|
| G
|
Exoc5
|
exocyst complex component 5
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to EXOC5 protein]
|
CTD |
PMID:26598702 |
|
NCBI chr15:24,788,738...24,834,941
Ensembl chr15:24,790,337...24,834,970
|
|
| G
|
Exog
|
exo/endonuclease G
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of EXOG mRNA
|
CTD |
PMID:15761015 |
|
NCBI chr 8:128,062,688...128,082,529
Ensembl chr 8:128,059,126...128,083,460
|
|
| G
|
Exosc2
|
exosome component 2
|
decreases expression increases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of EXOSC2 mRNA Arsenic Trioxide results in increased expression of EXOSC2 mRNA
|
CTD |
PMID:18231732 PMID:39716349 |
|
NCBI chr 3:35,360,652...35,370,948
Ensembl chr 3:35,360,666...35,371,373
|
|
| G
|
Exosc5
|
exosome component 5
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to EXOSC5 protein]
|
CTD |
PMID:26598702 |
|
NCBI chr 1:90,295,495...90,305,047
Ensembl chr 1:90,293,797...90,305,046
|
|
| G
|
Ext2
|
exostosin glycosyltransferase 2
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of EXT2 mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr 3:100,120,776...100,253,424
Ensembl chr 3:100,120,776...100,253,596
|
|
| G
|
Eya3
|
EYA transcriptional coactivator and phosphatase 3
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of EYA3 mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr 5:150,090,535...150,218,855
Ensembl chr 5:150,137,256...150,218,852
|
|
| G
|
Eya4
|
EYA transcriptional coactivator and phosphatase 4
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of EYA4 mRNA
|
CTD |
PMID:26705709 |
|
NCBI chr 1:23,991,431...24,235,132
Ensembl chr 1:23,991,431...24,235,131
|
|
| G
|
Ezh2
|
enhancer of zeste 2 polycomb repressive complex 2 subunit
|
decreases expression increases expression multiple interactions decreases response to substance
|
ISO
|
Arsenic Trioxide results in decreased expression of EZH2 mRNA; Arsenic Trioxide results in decreased expression of EZH2 protein Arsenic Trioxide results in increased expression of EZH2 protein Arsenic Trioxide inhibits the reaction [EZH2 protein binds to RELA protein] EZH2 protein results in decreased susceptibility to Arsenic Trioxide
|
CTD |
PMID:26592252 PMID:30612216 PMID:35467087 |
|
NCBI chr 4:77,624,223...77,698,598
Ensembl chr 4:77,624,223...77,687,183
|
|
| G
|
Ezr
|
ezrin
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of EZR mRNA; Arsenic Trioxide results in increased expression of EZR protein
|
CTD |
PMID:22521957 PMID:25419056 |
|
NCBI chr 1:49,373,033...49,416,573
Ensembl chr 1:49,373,035...49,416,573
|
|
| G
|
F12
|
coagulation factor XII
|
decreases response to substance
|
ISO
|
F12 protein results in decreased susceptibility to Arsenic Trioxide
|
CTD |
PMID:20707922 |
|
NCBI chr17:9,212,819...9,220,664
Ensembl chr17:9,212,819...9,220,664
|
|
| G
|
F13a1
|
coagulation factor XIII A1 chain
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of F13A1 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr17:28,021,197...28,197,960
Ensembl chr17:28,020,845...28,197,948
|
|
| G
|
F2r
|
coagulation factor II (thrombin) receptor
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of F2R mRNA
|
CTD |
PMID:22535156 |
|
NCBI chr 2:28,604,066...28,620,579
Ensembl chr 2:28,604,066...28,620,579
|
|
| G
|
F2rl1
|
F2R like trypsin receptor 1
|
decreases response to substance increases expression
|
ISO
|
F2RL1 protein results in decreased susceptibility to Arsenic Trioxide Arsenic Trioxide results in increased expression of F2RL1 mRNA
|
CTD |
PMID:20707922 PMID:25258189 |
|
NCBI chr 2:28,507,003...28,519,954
Ensembl chr 2:28,507,003...28,519,954
|
|
| G
|
F3
|
coagulation factor III, tissue factor
|
decreases expression affects expression multiple interactions
|
ISO
|
Arsenic Trioxide results in decreased expression of F3 mRNA; Arsenic Trioxide results in decreased expression of F3 protein Arsenic Trioxide affects the expression of F3 protein Arsenic Trioxide inhibits the reaction [Tretinoin results in decreased expression of F3 mRNA]; Arsenic Trioxide inhibits the reaction [Tretinoin results in decreased expression of F3 protein]; Arsenic Trioxide results in decreased expression of and results in decreased activity of F3 protein
|
CTD |
PMID:10400422 PMID:10803529 PMID:11721405 PMID:11775254 PMID:11779431 PMID:11798557 PMID:11798779 PMID:11876987 PMID:14619570 PMID:15761015 PMID:16206674 PMID:17493354 PMID:19128835 More...
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|
NCBI chr 2:212,511,675...212,523,375
Ensembl chr 2:212,511,680...212,523,369
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| G
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F5
|
coagulation factor V
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of F5 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr13:79,046,657...79,116,247
Ensembl chr13:79,046,448...79,116,247
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| G
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F8
|
coagulation factor VIII
|
multiple interactions
|
ISO
|
[Tretinoin co-treated with Arsenic Trioxide] results in decreased expression of F8 protein
|
CTD |
PMID:15894607 |
|
NCBI chr18:155,237...187,186
Ensembl chr18:155,309...186,683
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| G
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Fa2h
|
fatty acid 2-hydroxylase
|
decreases expression decreases response to substance
|
ISO
|
Arsenic Trioxide results in decreased expression of FA2H mRNA FA2H protein results in decreased susceptibility to Arsenic Trioxide
|
CTD |
PMID:19128835 PMID:20707922 |
|
NCBI chr19:56,222,240...56,273,480
Ensembl chr19:56,222,242...56,273,623
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| G
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Faap20
|
FA core complex associated protein 20
|
multiple interactions increases expression
|
ISO
|
Metformin inhibits the reaction [Arsenic Trioxide results in increased expression of FAAP20 mRNA]
|
CTD |
PMID:29095437 |
|
NCBI chr 5:171,083,328...171,097,599
Ensembl chr 5:171,087,847...171,097,599
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| G
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Fabp1
|
fatty acid binding protein 1
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of FABP1 mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr 4:104,744,302...104,753,119
Ensembl chr 4:104,744,309...104,753,113
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| G
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Fabp2
|
fatty acid binding protein 2
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of FABP2 mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr 2:213,724,629...213,728,686
Ensembl chr 2:213,724,629...213,728,686
|
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| G
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Fabp3
|
fatty acid binding protein 3
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of FABP3 mRNA
|
CTD |
PMID:36801614 |
|
NCBI chr 5:147,936,027...147,942,870
Ensembl chr 5:147,936,119...147,942,881
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| G
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Fabp5
|
fatty acid binding protein 5
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of FABP5 mRNA
|
CTD |
PMID:22521957 |
|
NCBI chr 2:93,672,451...93,676,186
Ensembl chr 2:93,672,458...93,676,127
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|
| G
|
Fabp7
|
fatty acid binding protein 7
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of FABP7 mRNA
|
CTD |
PMID:26705709 PMID:35676786 |
|
NCBI chr20:37,667,125...37,673,299
Ensembl chr20:37,669,601...37,675,907
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| G
|
Fadd
|
Fas associated via death domain
|
increases expression multiple interactions
|
ISO
|
Arsenic Trioxide results in increased expression of FADD mRNA; Arsenic Trioxide results in increased expression of FADD protein FAS protein affects the reaction [Arsenic Trioxide results in increased expression of FADD protein]
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CTD |
PMID:34953944 |
|
NCBI chr 1:209,169,245...209,175,423
Ensembl chr 1:209,169,318...209,174,976
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| G
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Fads3
|
fatty acid desaturase 3
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of FADS3 mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr 1:216,110,547...216,127,431
Ensembl chr 1:216,110,201...216,141,758
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| G
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Fahd2a
|
fumarylacetoacetate hydrolase domain containing 2A
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of FAHD2A mRNA
|
CTD |
PMID:25258189 |
|
NCBI chr 3:135,110,480...135,118,653
Ensembl chr 3:135,109,482...135,118,853
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| G
|
Fam107a
|
family with sequence similarity 107, member A
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of FAM107A mRNA
|
CTD |
PMID:35676786 |
|
NCBI chr15:19,038,726...19,060,644
Ensembl chr15:19,038,616...19,065,219
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| G
|
Fam107b
|
family with sequence similarity 107, member B
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of FAM107B mRNA
|
CTD |
PMID:24356939 |
|
NCBI chr17:79,387,795...79,594,165
Ensembl chr17:79,387,795...79,594,288
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| G
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Fam110b
|
family with sequence similarity 110, member B
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of FAM110B mRNA
|
CTD |
PMID:15761015 |
|
NCBI chr 5:23,587,093...23,727,188
Ensembl chr 5:23,586,867...23,799,583
|
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| G
|
Fam117b
|
family with sequence similarity 117, member B
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of FAM117B mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 9:68,834,334...68,902,543
Ensembl chr 9:68,834,354...68,902,543
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| G
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Fam120a
|
family with sequence similarity 120 member A
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of FAM120A mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr17:15,890,151...15,981,337
Ensembl chr17:15,890,605...15,981,332
|
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| G
|
Fam199x
|
family with sequence similarity 199, X-linked
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of FAM199X mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr X:105,176,504...105,212,207
Ensembl chr X:105,176,504...105,212,207
|
|
| G
|
Fam20c
|
FAM20C, golgi associated secretory pathway kinase
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of FAM20C mRNA
|
CTD |
PMID:22521957 |
|
NCBI chr12:20,940,654...20,999,072
Ensembl chr12:20,940,654...20,998,318
|
|
| G
|
Fam217b
|
family with sequence similarity 217, member B
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of FAM217B mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr 3:185,883,277...185,892,976
Ensembl chr 3:185,883,367...185,892,974
|
|
| G
|
Fam220a
|
family with sequence similarity 220, member A
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of FAM220A mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr12:16,111,593...16,127,584
Ensembl chr12:16,109,425...16,133,421
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|
| G
|
Fanca
|
FA complementation group A
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of FANCA mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr19:68,210,562...68,271,080
Ensembl chr19:68,212,643...68,271,019
|
|
| G
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Fancc
|
FA complementation group C
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of FANCC mRNA
|
CTD |
PMID:15070760 |
|
NCBI chr17:1,686,374...1,818,672
Ensembl chr17:1,687,017...1,835,096
|
|
| G
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Fancd2
|
FA complementation group D2
|
multiple interactions
|
ISO
|
[Arsenic Trioxide results in decreased activity of FANCD2 protein] which results in increased susceptibility to diepoxybutane; [Arsenic Trioxide results in decreased activity of FANCD2 protein] which results in increased susceptibility to Hydroxyurea; [Arsenic Trioxide results in decreased activity of FANCD2 protein] which results in increased susceptibility to Mitomycin
|
CTD |
PMID:25092648 |
|
NCBI chr 4:148,234,633...148,299,035
Ensembl chr 4:148,234,708...148,299,035
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|
| G
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Fap
|
fibroblast activation protein, alpha
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of FAP mRNA
|
CTD |
PMID:25258189 |
|
NCBI chr 3:67,547,398...67,616,271
Ensembl chr 3:67,546,921...67,617,601
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|
| G
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Fas
|
Fas cell surface death receptor
|
multiple interactions increases expression increases response to substance
|
ISO
|
[Arsenic Trioxide co-treated with Curcumin] results in increased expression of FAS protein; [sanguinarine co-treated with Arsenic Trioxide] results in increased expression of FAS mRNA; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased expression of FAS protein]; FAS protein affects the reaction [Arsenic Trioxide results in increased cleavage of CASP3 protein]; FAS protein affects the reaction [Arsenic Trioxide results in increased cleavage of CASP8 protein]; FAS protein affects the reaction [Arsenic Trioxide results in increased expression of FADD protein]; FAS protein affects the reaction [Arsenic Trioxide results in increased expression of FAS protein]; FAS protein affects the reaction [Arsenic Trioxide results in increased expression of FASLG protein]; NFKBIA protein inhibits the reaction [Arsenic Trioxide results in increased expression of FAS protein] Arsenic Trioxide results in increased expression of FAS; Arsenic Trioxide results in increased expression of FAS mRNA; Arsenic Trioxide results in increased expression of FAS protein FAS results in increased susceptibility to Arsenic Trioxide
|
CTD |
PMID:11135700 PMID:12126518 PMID:12452020 PMID:12478894 PMID:12684647 PMID:12975549 PMID:15382040 PMID:15979894 PMID:16029599 PMID:17530438 PMID:20819644 PMID:24345465 PMID:24356939 PMID:27430728 PMID:34953944 PMID:38275666 More...
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|
NCBI chr 1:241,212,155...241,245,774
Ensembl chr 1:241,205,935...241,246,104
|
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| G
|
Faslg
|
Fas ligand
|
multiple interactions increases expression decreases expression affects expression
|
ISO
|
[Arsenic Trioxide co-treated with Curcumin] results in increased expression of FASLG protein; [Arsenic Trioxide co-treated with VS-5584] results in increased expression of FASLG mRNA; [sanguinarine co-treated with Arsenic Trioxide] results in increased expression of FASLG mRNA; Arsenic Trioxide promotes the reaction [puerarin results in increased expression of FASLG protein]; Bortezomib promotes the reaction [Arsenic Trioxide results in increased activity of FASLG]; FAS protein affects the reaction [Arsenic Trioxide results in increased expression of FASLG protein]; FOXO3 protein affects the reaction [Arsenic Trioxide results in increased expression of FASLG protein] Arsenic Trioxide results in increased expression of FASL protein; Arsenic Trioxide results in increased expression of FASLG; Arsenic Trioxide results in increased expression of FASLG mRNA; Arsenic Trioxide results in increased expression of FASLG protein Arsenic Trioxide results in decreased expression of FASLG mRNA Arsenic Trioxide affects the expression of FASL protein
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CTD |
PMID:12684647 PMID:12975549 PMID:17530438 PMID:20416161 PMID:20471514 PMID:20819644 PMID:23911876 PMID:24345465 PMID:25410152 PMID:27430728 PMID:29574283 PMID:31421153 PMID:34953944 More...
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|
NCBI chr13:76,680,885...76,706,042
Ensembl chr13:76,688,243...76,695,503
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| G
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Fasn
|
fatty acid synthase
|
decreases expression increases expression multiple interactions
|
ISO
|
Arsenic Trioxide results in decreased expression of FASN mRNA Arsenic Trioxide results in increased expression of FASN protein Taurine inhibits the reaction [Arsenic Trioxide results in decreased expression of FASN mRNA] [Arsenic Trioxide co-treated with Tretinoin] results in decreased expression of FASN mRNA
|
CTD |
PMID:25419056 PMID:30237538 PMID:38179723 |
|
NCBI chr10:106,570,415...106,588,581
Ensembl chr10:106,570,413...106,588,583
|
|
| G
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Fastk
|
Fas-activated serine/threonine kinase
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of FASTK mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr 4:11,624,697...11,628,769
Ensembl chr 4:11,624,689...11,629,867
|
|
| G
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Fat1
|
FAT atypical cadherin 1
|
multiple interactions increases expression
|
ISO
|
[Arsenic Trioxide co-treated with Ascorbic Acid] results in increased expression of FAT1 mRNA Arsenic Trioxide results in increased expression of FAT1 mRNA
|
CTD |
PMID:25555879 |
|
NCBI chr16:53,909,759...54,029,175
Ensembl chr16:53,909,556...54,028,609
|
|
| G
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Fbf1
|
Fas binding factor 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of FBF1 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr10:101,874,661...101,900,497
Ensembl chr10:101,874,664...101,900,738
|
|
| G
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Fbh1
|
F-box DNA helicase 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of FBH1 mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr17:71,659,351...71,697,431
Ensembl chr17:71,659,249...71,697,432
|
|
| G
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Fbln1
|
fibulin 1
|
increases expression multiple interactions
|
ISO
|
Arsenic Trioxide results in increased expression of FBLN1 mRNA [Arsenic Trioxide co-treated with Ascorbic Acid] results in increased expression of FBLN1 mRNA
|
CTD |
PMID:25555879 |
|
NCBI chr 7:118,190,347...118,269,965
Ensembl chr 7:118,190,478...118,269,965
|
|
| G
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Fbln5
|
fibulin 5
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of FBLN5 mRNA
|
CTD |
PMID:15761015 |
|
NCBI chr 6:126,664,100...126,742,847
Ensembl chr 6:126,664,100...126,746,296
|
|
| G
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Fbn2
|
fibrillin 2
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of FBN2 protein
|
CTD |
PMID:15894607 |
|
NCBI chr18:53,696,197...53,901,992
Ensembl chr18:53,697,708...53,902,191
|
|
| G
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Fbp1
|
fructose-bisphosphatase 1
|
increases expression multiple interactions decreases expression
|
ISO
|
Arsenic Trioxide results in increased expression of FBP1 mRNA Taurine inhibits the reaction [Arsenic Trioxide results in increased expression of FBP1 mRNA] Arsenic Trioxide results in increased expression of FBP1 protein Arsenic Trioxide results in decreased expression of FBP1 mRNA
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CTD |
PMID:19128835 PMID:25419056 PMID:30362509 |
|
NCBI chr17:2,212,941...2,235,749
Ensembl chr17:2,213,492...2,235,746
|
|
| G
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Fbxl4
|
F-box and leucine-rich repeat protein 4
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of FBXL4 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 5:40,752,513...40,826,154
Ensembl chr 5:40,752,521...40,850,826
|
|
| G
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Fbxl7
|
F-box and leucine-rich repeat protein 7
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of FBXL7 mRNA
|
CTD |
PMID:15725085 |
|
NCBI chr 2:78,870,236...79,239,697
Ensembl chr 2:78,871,287...79,239,697
|
|
| G
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Fbxl8
|
F-box and leucine-rich repeat protein 8
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of FBXL8 mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr19:50,048,221...50,057,191
Ensembl chr19:50,052,393...50,057,453
|
|
| G
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Fbxo25
|
F-box protein 25
|
multiple interactions
|
ISO
|
[Tretinoin co-treated with Arsenic Trioxide] results in decreased expression of FBXO25 mRNA
|
CTD |
PMID:15894607 |
|
NCBI chr16:82,370,123...82,404,002
Ensembl chr16:82,370,059...82,403,919
|
|
| G
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Fbxo30
|
F-box protein 30
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of FBXO30 mRNA
|
CTD |
PMID:27829220 |
|
NCBI chr 1:7,475,636...7,491,719
Ensembl chr 1:7,475,575...7,493,199
|
|
| G
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Fbxo32
|
F-box protein 32
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of FBXO32 mRNA Arsenic Trioxide results in increased expression of FBXO32 protein
|
CTD |
PMID:24356939 PMID:32184170 PMID:32635466 |
|
NCBI chr 7:91,620,925...91,654,491
Ensembl chr 7:91,620,925...91,654,491
|
|
| G
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Fbxo38
|
F-box protein 38
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of FBXO38 mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr18:58,227,253...58,274,320
Ensembl chr18:58,227,262...58,274,262
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|
| G
|
Fbxw4
|
F-box and WD repeat domain containing 4
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of FBXW4 mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr 1:254,375,921...254,465,173
Ensembl chr 1:254,375,923...254,463,277
|
|
| G
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Fbxw5
|
F-box and WD repeat domain containing 5
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of FBXW5 mRNA
|
CTD |
PMID:35676786 |
|
NCBI chr 3:28,720,670...28,725,237
Ensembl chr 3:28,720,778...28,725,235
|
|
| G
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Fbxw7
|
F-box and WD repeat domain containing 7
|
increases expression multiple interactions
|
ISO
|
Arsenic Trioxide results in increased expression of FBXW7 protein [Arsenic Trioxide binds to PIN1 protein] affects the reaction [Arsenic Trioxide results in decreased expression of FBXW7 protein]; Arsenic Trioxide promotes the reaction [Tretinoin results in decreased expression of FBXW7 protein]; PIN1 protein affects the reaction [Arsenic Trioxide results in increased expression of FBXW7 protein]; Tretinoin promotes the reaction [Arsenic Trioxide results in decreased expression of FBXW7 protein]
|
CTD |
PMID:24801890 PMID:30093655 PMID:31597699 |
|
NCBI chr 2:172,447,738...172,609,591
Ensembl chr 2:172,447,738...172,609,591
|
|
| G
|
Fcer1g
|
Fc epsilon receptor Ig
|
multiple interactions
|
ISO
|
[Arsenic Trioxide co-treated with nilotinib] affects the expression of FCER1G mRNA
|
CTD |
PMID:28786057 |
|
NCBI chr13:86,181,908...86,186,766
Ensembl chr13:86,181,908...86,186,859
|
|
| G
|
Fcgr1a
|
Fc gamma receptor 1A
|
increases expression multiple interactions
|
ISO
|
Arsenic Trioxide results in increased expression of FCGR1A protein 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Arsenic Trioxide inhibits the reaction [Sirolimus results in decreased expression of FCGR1A protein]]; Arsenic Trioxide inhibits the reaction [Sirolimus results in decreased expression of FCGR1A protein]
|
CTD |
PMID:25758096 |
|
NCBI chr 2:186,539,941...186,548,941
Ensembl chr 2:186,539,942...186,548,858
|
|
| G
|
Fcgr3a
|
Fc gamma receptor 3A
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of FCGR3A mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr13:85,782,636...85,792,656
Ensembl chr13:85,782,490...85,792,651
|
|
| G
|
Fcrl5
|
Fc receptor-like 5
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of FCRL5 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 2:175,179,630...175,211,180
Ensembl chr 2:175,179,690...175,211,039
|
|
| G
|
Fdps
|
farnesyl diphosphate synthase
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of FDPS mRNA
|
CTD |
PMID:27829220 |
|
NCBI chr 2:176,795,192...176,804,816
Ensembl chr 2:176,795,192...176,807,136
|
|
| G
|
Fen1
|
flap structure-specific endonuclease 1
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of FEN1 mRNA
|
CTD |
PMID:34413873 |
|
NCBI chr 1:216,270,016...216,274,873
Ensembl chr 1:216,269,163...216,275,016
|
|
| G
|
Fer
|
FER tyrosine kinase
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of FER mRNA
|
CTD |
PMID:29633893 |
|
NCBI chr 9:110,967,317...111,274,315
Ensembl chr 9:110,967,390...111,274,315
|
|
| G
|
Ferd3l
|
Fer3-like bHLH transcription factor
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to FERD3L protein]
|
CTD |
PMID:26598702 |
|
NCBI chr 6:56,372,778...56,373,667
Ensembl chr 6:56,372,479...56,373,501
|
|
| G
|
Fermt1
|
FERM domain containing kindlin 1
|
decreases response to substance
|
ISO
|
FERMT1 protein results in decreased susceptibility to Arsenic Trioxide
|
CTD |
PMID:20707922 |
|
NCBI chr 3:140,624,434...140,666,419
Ensembl chr 3:140,624,434...140,666,419
|
|
| G
|
Fermt2
|
FERM domain containing kindlin 2
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of FERMT2 mRNA
|
CTD |
PMID:27829220 |
|
NCBI chr15:21,162,603...21,257,995
Ensembl chr15:21,162,605...21,258,115
|
|
| G
|
Fermt3
|
FERM domain containing kindlin 3
|
multiple interactions
|
ISO
|
[Tretinoin co-treated with Arsenic Trioxide] results in increased expression of FERMT3 mRNA
|
CTD |
PMID:15894607 |
|
NCBI chr 1:213,618,691...213,636,889
Ensembl chr 1:213,618,208...213,636,273
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| G
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Ffar2
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free fatty acid receptor 2
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of FFAR2 mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr 1:95,199,277...95,202,599
Ensembl chr 1:95,199,271...95,202,623
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| G
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Fgf1
|
fibroblast growth factor 1
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of FGF1 mRNA
|
CTD |
PMID:21461292 |
|
NCBI chr18:30,937,670...31,023,786
Ensembl chr18:30,939,870...30,961,393
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| G
|
Fgf10
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fibroblast growth factor 10
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of FGF10 mRNA
|
CTD |
PMID:26705709 |
|
NCBI chr 2:52,533,939...52,610,980
Ensembl chr 2:52,533,939...52,610,980
|
|
| G
|
Fgf12
|
fibroblast growth factor 12
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of FGF12 mRNA
|
CTD |
PMID:22521957 |
|
NCBI chr11:85,501,947...86,069,543
Ensembl chr11:85,501,936...86,069,543
|
|
| G
|
Fgf14
|
fibroblast growth factor 14
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of FGF14 mRNA
|
CTD |
PMID:26705709 |
|
NCBI chr15:107,442,800...108,086,486
Ensembl chr15:107,451,634...108,085,808
|
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| G
|
Fgf2
|
fibroblast growth factor 2
|
multiple interactions decreases expression
|
ISO
|
Arsenic Trioxide inhibits the reaction [FGF2 protein results in increased phosphorylation of MAPK1 protein]; Arsenic Trioxide inhibits the reaction [FGF2 protein results in increased phosphorylation of MAPK3 protein] Arsenic Trioxide results in decreased expression of FGF2 mRNA
|
CTD |
PMID:15723287 PMID:22521957 |
|
NCBI chr 2:122,164,454...122,218,796
Ensembl chr 2:122,164,454...122,224,493
|
|
| G
|
Fgf6
|
fibroblast growth factor 6
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of FGF6 mRNA
|
CTD |
PMID:35676786 |
|
NCBI chr 4:161,541,089...161,549,624
Ensembl chr 4:161,541,089...161,553,521
|
|
| G
|
Fgf7
|
fibroblast growth factor 7
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of FGF7 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 3:133,734,557...133,786,678
Ensembl chr 3:133,734,673...133,786,328
|
|
| G
|
Fgfr1
|
Fibroblast growth factor receptor 1
|
increases expression decreases response to substance multiple interactions decreases phosphorylation decreases expression
|
ISO
|
Arsenic Trioxide results in increased expression of FGFR1 mRNA FGFR1 protein results in decreased susceptibility to Arsenic Trioxide Arsenic Trioxide promotes the reaction [PD 173074 results in decreased expression of FGFR1 protein]; PD 173074 promotes the reaction [Arsenic Trioxide results in decreased expression of FGFR1 protein] Arsenic Trioxide results in decreased phosphorylation of FGFR1 protein mutant form Arsenic Trioxide results in decreased expression of FGFR1 mRNA; Arsenic Trioxide results in decreased expression of FGFR1 protein
|
CTD |
PMID:15761015 PMID:17027752 PMID:17258074 PMID:19128835 PMID:20458559 PMID:27794399 More...
|
|
NCBI chr16:73,194,631...73,249,855
Ensembl chr16:73,194,631...73,249,855
|
|
| G
|
Fgfr1op2
|
FGFR1 oncogene partner 2
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of FGFR1OP2 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 4:181,222,298...181,243,318
Ensembl chr 4:181,222,323...181,243,322
|
|
| G
|
Fgfr2
|
fibroblast growth factor receptor 2
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of FGFR2 mRNA
|
CTD |
PMID:15761015 |
|
NCBI chr 1:194,175,703...194,280,914
Ensembl chr 1:194,175,705...194,280,914
|
|
| G
|
Fgl1
|
fibrinogen-like 1
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to FGL1 protein]
|
CTD |
PMID:26598702 |
|
NCBI chr16:57,824,127...57,854,413
Ensembl chr16:57,824,200...57,854,429
|
|
| G
|
Fgl2
|
fibrinogen-like 2
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of FGL2 mRNA
|
CTD |
PMID:19128835 |
|
NCBI chr 4:14,602,762...14,608,405
Ensembl chr 4:14,602,771...14,608,405
|
|
| G
|
Fgr
|
FGR proto-oncogene, Src family tyrosine kinase
|
increases expression multiple interactions
|
ISO
|
Arsenic Trioxide results in increased expression of FGR mRNA [Arsenic Trioxide co-treated with Tretinoin] results in increased expression of FGR mRNA
|
CTD |
PMID:15761015 PMID:38179723 |
|
NCBI chr 5:150,473,767...150,503,524
Ensembl chr 5:150,473,792...150,503,169
|
|
| G
|
Fh
|
fumarate hydratase
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of FH mRNA
|
CTD |
PMID:22521957 |
|
NCBI chr13:90,056,565...90,082,450
Ensembl chr13:90,056,570...90,089,627
|
|
| G
|
Fhl1
|
four and a half LIM domains 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of FHL1 mRNA
|
CTD |
PMID:17258074 |
|
NCBI chr X:139,592,794...139,652,290
Ensembl chr X:139,592,604...139,652,282
|
|
| G
|
Fhl2
|
four and a half LIM domains 2
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of FHL2 mRNA
|
CTD |
PMID:26705709 PMID:36801614 |
|
NCBI chr 9:52,881,091...52,954,540
Ensembl chr 9:52,880,998...52,923,326
|
|
| G
|
Fhod1
|
formin homology 2 domain containing 1
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of FHOD1 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr19:50,116,415...50,135,868
Ensembl chr19:50,116,415...50,135,330
|
|
| G
|
Filip1
|
filamin A interacting protein 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of FILIP1 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 8:89,641,509...89,836,772
Ensembl chr 8:89,644,579...89,802,771
|
|
| G
|
Fkbp11
|
FKBP prolyl isomerase 11
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of FKBP11 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 7:131,750,828...131,757,784
Ensembl chr 7:131,750,672...131,770,123
|
|
| G
|
Fkbp5
|
FKBP prolyl isomerase 5
|
affects expression multiple interactions
|
ISO
|
Arsenic Trioxide affects the expression of FKBP5 mRNA Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to FKBP5 protein]
|
CTD |
PMID:25873331 PMID:26598702 |
|
NCBI chr20:6,458,931...6,577,227
Ensembl chr20:6,458,940...6,543,118
|
|
| G
|
Fkbp7
|
FKBP prolyl isomerase 7
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of FKBP7 mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr 3:82,016,647...82,030,913
Ensembl chr 3:82,016,513...82,028,573
|
|
| G
|
Flcn
|
folliculin
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of FLCN mRNA
|
CTD |
PMID:34108876 |
|
NCBI chr10:45,088,164...45,107,581
Ensembl chr10:45,088,167...45,107,309
|
|
| G
|
Flna
|
filamin A
|
increases expression decreases expression
|
ISO
|
Arsenic Trioxide results in increased expression of FLNA mRNA Arsenic Trioxide results in decreased expression of FLNA mRNA
|
CTD |
PMID:35676786 PMID:39716349 |
|
NCBI chr X:157,159,051...157,185,559
Ensembl chr X:157,159,051...157,182,343
|
|
| G
|
Flnb
|
filamin B
|
increases expression decreases expression decreases response to substance
|
ISO
|
Arsenic Trioxide results in increased expression of FLNB protein Arsenic Trioxide results in decreased expression of FLNB protein FLNB protein results in decreased susceptibility to Arsenic Trioxide Arsenic Trioxide results in decreased expression of FLNB mRNA
|
CTD |
PMID:20707922 PMID:25419056 PMID:30093655 PMID:39716349 |
|
NCBI chr15:19,392,212...19,525,278
Ensembl chr15:19,392,216...19,525,209
|
|
| G
|
Flnc
|
filamin C
|
increases expression multiple interactions
|
ISO
|
Arsenic Trioxide results in increased expression of FLNC mRNA; Arsenic Trioxide results in increased expression of FLNC protein FLNC protein affects the reaction [Arsenic Trioxide results in increased cleavage of GSDME protein]
|
CTD |
PMID:36801614 |
|
NCBI chr 4:58,999,445...59,027,240
Ensembl chr 4:58,999,547...59,027,240
|
|
| G
|
Flrt3
|
fibronectin leucine rich transmembrane protein 3
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of FLRT3 mRNA
|
CTD |
PMID:27829220 |
|
NCBI chr 3:148,448,115...148,461,458
Ensembl chr 3:148,439,354...148,461,650
|
|
| G
|
Flt1
|
Fms related receptor tyrosine kinase 1
|
increases expression decreases expression
|
ISO
|
Arsenic Trioxide results in increased expression of FLT1 mRNA Arsenic Trioxide results in decreased expression of FLT1
|
CTD |
PMID:15073043 PMID:18161919 |
|
NCBI chr12:12,333,050...12,504,750
Ensembl chr12:12,333,430...12,504,750
|
|
| G
|
Flt3
|
Fms related receptor tyrosine kinase 3
|
decreases phosphorylation increases degradation multiple interactions increases expression
|
ISO
|
Arsenic Trioxide results in decreased phosphorylation of FLT3 protein Arsenic Trioxide results in increased degradation of FLT3 protein mutant form Arsenic Trioxide inhibits the reaction [bafilomycin A results in increased expression of FLT3 protein modified form]; Arsenic Trioxide promotes the reaction [SQSTM1 protein binds to FLT3 protein mutant form]; ATG5 protein promotes the reaction [Arsenic Trioxide results in increased degradation of FLT3 protein mutant form]; ATG7 protein promotes the reaction [Arsenic Trioxide results in increased degradation of FLT3 protein mutant form]; bafilomycin A inhibits the reaction [Arsenic Trioxide results in increased degradation of FLT3 protein mutant form] Arsenic Trioxide results in increased expression of FLT3 gene mutant form
|
CTD |
PMID:17121903 PMID:32284743 PMID:38746032 |
|
NCBI chr12:12,660,035...12,735,584
Ensembl chr12:12,659,946...12,735,581
|
|
| G
|
Flt4
|
Fms related receptor tyrosine kinase 4
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of FLT4 mRNA; Arsenic Trioxide results in decreased expression of FLT4 protein
|
CTD |
PMID:19099632 PMID:38275666 |
|
NCBI chr10:34,414,834...34,455,878
Ensembl chr10:34,414,733...34,456,645
|
|
| G
|
Fmn2
|
formin 2
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of FMN2 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr13:88,986,863...89,303,789
Ensembl chr13:88,986,842...89,303,789
|
|
| G
|
Fmod
|
fibromodulin
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of FMOD mRNA
|
CTD |
PMID:26705709 PMID:35676786 |
|
NCBI chr13:48,045,567...48,056,184
Ensembl chr13:47,990,774...48,056,183
|
|
| G
|
Fn1
|
fibronectin 1
|
decreases expression multiple interactions increases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of FN1 protein [Arsenic Trioxide co-treated with FN1 protein] results in decreased expression of POU5F1 mRNA Arsenic Trioxide results in increased expression of FN1 mRNA [Arsenic Trioxide co-treated with apatinib] results in decreased expression of FN1 mRNA
|
CTD |
PMID:17258074 PMID:20458559 PMID:22641096 PMID:30093655 PMID:39223679 |
|
NCBI chr 9:80,645,507...80,714,200
Ensembl chr 9:80,645,507...80,714,137
|
|
| G
|
Fn3krp
|
fructosamine-3-kinase-related protein
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of FN3KRP mRNA
|
CTD |
PMID:25555879 |
|
NCBI chr10:107,186,695...107,195,419
|
|
| G
|
Fnbp1l
|
formin binding protein 1-like
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of FNBP1L mRNA
|
CTD |
PMID:15761015 |
|
NCBI chr 2:213,331,871...213,432,821
Ensembl chr 2:213,318,662...213,423,051
|
|
| G
|
Fnbp4
|
formin binding protein 4
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of FNBP4 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 3:97,188,852...97,218,916
Ensembl chr 3:97,188,884...97,219,435
|
|
| G
|
Fndc1
|
fibronectin type III domain containing 1
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of FNDC1 mRNA
|
CTD |
PMID:26705709 |
|
NCBI chr 1:49,686,856...49,769,263
Ensembl chr 1:49,686,856...49,769,263
|
|
| G
|
Fndc11
|
fibronectin type III domain containing 11
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to FNDC11 protein]
|
CTD |
PMID:26598702 |
|
NCBI chr 3:188,708,045...188,710,670
Ensembl chr 3:188,707,334...188,714,164
|
|
| G
|
Fnip1
|
folliculin interacting protein 1
|
increases expression multiple interactions
|
ISO
|
Arsenic Trioxide results in increased expression of FNIP1 mRNA [Arsenic Trioxide co-treated with apatinib] results in increased expression of FNIP1 mRNA
|
CTD |
PMID:26705709 PMID:39223679 |
|
NCBI chr10:39,068,432...39,151,552
Ensembl chr10:39,068,445...39,151,552
|
|
| G
|
Fnip2
|
folliculin interacting protein 2
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of FNIP2 mRNA
|
CTD |
PMID:27829220 |
|
NCBI chr 2:166,894,726...167,006,490
Ensembl chr 2:166,897,075...167,006,055
|
|
| G
|
Fos
|
Fos proto-oncogene, AP-1 transcription factor subunit
|
decreases expression increases expression affects expression decreases activity multiple interactions
|
ISO EXP
|
Arsenic Trioxide results in decreased expression of FOS mRNA Arsenic Trioxide results in increased expression of FOS mRNA; Arsenic Trioxide results in increased expression of FOS protein Arsenic Trioxide affects the expression of FOS mRNA; Arsenic Trioxide affects the expression of FOS protein Arsenic Trioxide results in decreased activity of FOS protein [Arsenic Trioxide results in increased phosphorylation of and results in increased activity of FOS protein] promotes the reaction [FOS protein binds to CDKN1A promoter]; [Arsenic Trioxide results in increased phosphorylation of and results in increased activity of FOS protein] promotes the reaction [FOS protein results in increased expression of CDKN1A mRNA]; Arsenic Trioxide promotes the reaction [[FOS protein binds to JUN promoter] which binds to CDKN1A promoter]; Arsenic Trioxide promotes the reaction [[FOS protein binds to JUN protein] which results in increased expression of CDKN1A mRNA]; Arsenic Trioxide promotes the reaction [FOS protein binds to CDKN1A promoter]; Arsenic Trioxide promotes the reaction [MAPK1 protein promotes the reaction [FOS protein binds to CDKN1A promoter]]; Arsenic Trioxide promotes the reaction [MAPK3 protein promotes the reaction [FOS protein binds to CDKN1A promoter]]; Arsenic Trioxide promotes the reaction [nilotinib results in increased expression of FOS mRNA]; Arsenic Trioxide promotes the reaction [nilotinib results in increased expression of FOS protein]; Arsenic Trioxide results in increased expression of and results in increased phosphorylation of FOS protein; Atrazine promotes the reaction [Arsenic Trioxide results in increased expression of FOS mRNA]; U 0126 inhibits the reaction [Arsenic Trioxide results in increased expression of and results in increased phosphorylation of FOS protein]; U 0126 inhibits the reaction [Arsenic Trioxide results in increased expression of FOS mRNA]; U 0126 inhibits the reaction [Arsenic Trioxide results in increased expression of FOS protein]
|
CTD |
PMID:11678611 PMID:12749819 PMID:14682389 PMID:18822310 PMID:19410645 PMID:19444595 PMID:20458559 PMID:23883479 PMID:24956101 PMID:25258189 PMID:25574600 PMID:25791921 PMID:27829220 PMID:29049341 PMID:29223816 PMID:29633893 PMID:35676786 PMID:37969188 More...
|
|
NCBI chr 6:110,852,188...110,855,054
Ensembl chr 6:110,852,190...110,855,598
|
|
| G
|
Fosb
|
FosB proto-oncogene, AP-1 transcription factor subunit
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of FOSB mRNA
|
CTD |
PMID:19410645 |
|
NCBI chr 1:88,082,324...88,089,506
Ensembl chr 1:88,082,127...88,089,477
|
|
| G
|
Fosl1
|
FOS like 1, AP-1 transcription factor subunit
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of FOSL1 mRNA
|
CTD |
PMID:29633893 PMID:36801614 |
|
NCBI chr 1:212,183,885...212,192,391
Ensembl chr 1:212,183,833...212,192,391
|
|
| G
|
Foxa1
|
forkhead box A1
|
affects methylation multiple interactions
|
ISO
|
Arsenic Trioxide affects the methylation of FOXA1 promoter [Arsenic Trioxide co-treated with Bortezomib] results in increased expression of FOXA1 mRNA
|
CTD |
PMID:25913414 PMID:26046465 |
|
NCBI chr 6:80,838,380...80,871,195
Ensembl chr 6:80,800,960...80,871,191
|
|
| G
|
Foxm1
|
forkhead box M1
|
increases expression decreases expression
|
ISO
|
Arsenic Trioxide results in increased expression of FOXM1 mRNA; Arsenic Trioxide results in increased expression of FOXM1 protein Arsenic Trioxide results in decreased expression of FOXM1 mRNA
|
CTD |
PMID:23255470 PMID:26705709 |
|
NCBI chr 4:163,325,628...163,338,100
Ensembl chr 4:163,325,614...163,337,172
|
|
| G
|
Foxo1
|
forkhead box O1
|
multiple interactions increases expression
|
ISO
|
Taurine inhibits the reaction [Arsenic Trioxide results in increased expression of FOXO1 mRNA] [Cisplatin co-treated with Arsenic Trioxide] results in decreased phosphorylation of FOXO1 protein
|
CTD |
PMID:23911876 PMID:29442453 PMID:29944906 PMID:30362509 PMID:34108876 |
|
NCBI chr 2:138,462,974...138,541,420
Ensembl chr 2:138,462,697...138,541,419
|
|
| G
|
Foxo3
|
forkhead box O3
|
decreases expression multiple interactions affects localization affects response to substance increases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of FOXO3 mRNA [Arsenic Trioxide co-treated with NVP-BKM120] results in increased expression of FOXO3 mRNA; [Cisplatin co-treated with Arsenic Trioxide] results in decreased phosphorylation of FOXO3 protein; Arsenic Trioxide results in increased expression of and results in decreased phosphorylation of and results in increased localization of FOXO3 protein; Arsenic Trioxide results in increased expression of and results in decreased phosphorylation of FOXO3 protein; Arsenic Trioxide results in increased expression of and results in increased localization of FOXO3 mRNA; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Arsenic Trioxide results in increased expression of FOXO3 protein]; FOXO3 protein affects the reaction [Arsenic Trioxide results in decreased expression of VEGFA protein]; FOXO3 protein affects the reaction [Arsenic Trioxide results in increased expression of FASLG protein]; TNF protein inhibits the reaction [Arsenic Trioxide results in increased expression of FOXO3 mRNA]; TNF protein inhibits the reaction [Arsenic Trioxide results in increased expression of FOXO3 protein] Arsenic Trioxide affects the localization of FOXO3 protein FOXO3 protein affects the susceptibility to Arsenic Trioxide FOXO3 protein affects the reaction [Arsenic Trioxide results in decreased expression of MKI67 protein]
|
CTD |
PMID:22521957 PMID:22988968 PMID:29944906 PMID:31421153 PMID:31539632 |
|
NCBI chr20:47,251,968...47,348,254
Ensembl chr20:47,255,878...47,346,845
|
|
| G
|
Foxo4
|
forkhead box O4
|
multiple interactions
|
ISO
|
[Arsenic Trioxide co-treated with NVP-BKM120] results in increased expression of FOXO4 mRNA
|
CTD |
PMID:31539632 |
|
NCBI chr X:70,425,218...70,432,120
Ensembl chr X:70,425,563...70,432,120
|
|
| G
|
Foxp3
|
forkhead box P3
|
increases expression decreases expression multiple interactions
|
ISO
|
Arsenic Trioxide results in increased expression of FOXP3 mRNA Arsenic Trioxide results in decreased expression of FOXP3 mRNA Arsenic Trioxide results in increased expression of and affects the localization of FOXP3 protein
|
CTD |
PMID:23802174 PMID:29950232 PMID:34108876 |
|
NCBI chr X:17,580,380...17,601,181
Ensembl chr X:17,580,380...17,595,894
|
|
| G
|
Foxred2
|
FAD-dependent oxidoreductase domain containing 2
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of FOXRED2 mRNA
|
CTD |
PMID:15761015 |
|
NCBI chr 7:111,402,322...111,419,056
Ensembl chr 7:111,402,322...111,417,988
|
|
| G
|
Fpgs
|
folylpolyglutamate synthase
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of FPGS mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr 3:36,370,505...36,391,314
Ensembl chr 3:36,370,300...36,391,068
|
|
| G
|
Fpr1
|
formyl peptide receptor 1
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of FPR1 mRNA
|
CTD |
PMID:29633893 |
|
NCBI chr 1:67,417,991...67,429,813
Ensembl chr 1:67,421,313...67,422,520
|
|
| G
|
Frat1
|
FRAT regulator of WNT signaling pathway 1
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of FRAT1 mRNA
|
CTD |
PMID:29633893 |
|
NCBI chr 1:250,587,641...250,590,189
Ensembl chr 1:250,587,506...250,603,039
|
|
| G
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Frk
|
fyn-related Src family tyrosine kinase
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of FRK mRNA
|
CTD |
PMID:15761015 |
|
NCBI chr20:39,820,441...39,926,065
Ensembl chr20:39,820,295...39,926,362
|
|
| G
|
Frmd4b
|
FERM domain containing 4B
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of FRMD4B mRNA
|
CTD |
PMID:35676786 |
|
NCBI chr 4:131,452,361...131,778,734
Ensembl chr 4:131,452,365...131,640,287
|
|
| G
|
Fryl
|
FRY like transcription coactivator
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of FRYL mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr14:35,307,225...35,545,199
Ensembl chr14:35,310,656...35,545,147
|
|
| G
|
Fscn1
|
fascin actin-bundling protein 1
|
decreases expression multiple interactions increases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of FSCN1 mRNA [Arsenic Trioxide results in decreased expression of MEG3 protein] promotes the reaction [NQO1 protein binds to FSCN1 protein]; Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to FSCN1 protein]; Arsenic Trioxide promotes the reaction [FSCN1 protein binds to NQO1 protein]; MEG3 inhibits the reaction [Arsenic Trioxide results in increased expression of FSCN1 protein]; NQO1 promotes the reaction [Arsenic Trioxide results in increased expression of FSCN1 protein]
|
CTD |
PMID:15070760 PMID:15761015 PMID:20458559 PMID:26598702 PMID:37424815 |
|
NCBI chr12:16,710,601...16,723,734
Ensembl chr12:16,710,601...16,723,734
|
|
| G
|
Fscn2
|
fascin actin-bundling protein 2, retinal
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of FSCN2 mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr10:106,121,038...106,139,683
Ensembl chr10:106,133,144...106,139,683
|
|
| G
|
Fst
|
follistatin
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to FST protein]
|
CTD |
PMID:26598702 |
|
NCBI chr 2:47,856,345...47,863,670
Ensembl chr 2:47,856,345...47,863,491
|
|
| G
|
Fstl4
|
follistatin-like 4
|
multiple interactions
|
ISO
|
[Tretinoin co-treated with Arsenic Trioxide] results in decreased expression of FSTL4 mRNA
|
CTD |
PMID:15894607 |
|
NCBI chr10:37,412,288...37,845,405
Ensembl chr10:37,412,288...37,845,393
|
|
| G
|
Fstl5
|
follistatin-like 5
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of FSTL5 mRNA
|
CTD |
PMID:26705709 |
|
NCBI chr 2:163,156,576...163,825,140
Ensembl chr 2:163,156,576...163,825,140
|
|
| G
|
Fth1
|
ferritin heavy chain 1
|
multiple interactions increases expression decreases response to substance decreases expression
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to FTH1 protein] Arsenic Trioxide results in increased expression of FTH1 mRNA FTH1 protein results in decreased susceptibility to Arsenic Trioxide Arsenic Trioxide results in decreased expression of FTH1 protein
|
CTD |
PMID:14703492 PMID:15725085 PMID:19417148 PMID:20458559 PMID:20707922 PMID:25003661 PMID:26598702 PMID:26705709 PMID:36509116 More...
|
|
NCBI chr 1:216,052,037...216,054,325
Ensembl chr 1:216,051,998...216,055,214
|
|
| G
|
Ftl1
|
ferritin light chain 1
|
multiple interactions increases expression
|
ISO
|
[Tretinoin co-treated with Arsenic Trioxide] results in increased expression of FTL mRNA Arsenic Trioxide results in increased expression of FTL mRNA
|
CTD |
PMID:15894607 PMID:20458559 PMID:26705709 |
|
NCBI chr 1:105,072,858...105,074,705
Ensembl chr X:45,399,355...45,399,915 Ensembl chr 2:45,399,355...45,399,915 Ensembl chr 1:45,399,355...45,399,915
|
|
| G
|
Ftmt
|
ferritin mitochondrial
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of FTMT mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr18:47,957,235...47,958,484
Ensembl chr18:47,957,228...47,958,768
|
|
| G
|
Ftsj1
|
FtsJ RNA 2'-O-methyltransferase 1
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of FTSJ1 mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr X:16,915,087...16,929,426
Ensembl chr X:16,916,033...16,923,999
|
|
| G
|
Ftx
|
FTX transcript, XIST regulator
|
affects expression
|
ISO
|
Arsenic Trioxide affects the expression of FTX mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr X:72,654,112...72,696,097
|
|
| G
|
Fubp1
|
far upstream element binding protein 1
|
increases response to substance decreases expression
|
ISO
|
FUBP1 protein results in increased susceptibility to Arsenic Trioxide Arsenic Trioxide results in decreased expression of FUBP1 protein
|
CTD |
PMID:19364129 PMID:20707922 PMID:25419056 |
|
NCBI chr 2:243,819,529...243,846,544
Ensembl chr 2:243,819,218...243,846,428
|
|
| G
|
Fuca1
|
alpha-L-fucosidase 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of FUCA1 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 5:153,436,262...153,453,512
Ensembl chr 5:153,436,248...153,453,511
|
|
| G
|
Fut11
|
fucosyltransferase 11
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of POFUT4 mRNA
|
CTD |
PMID:27829220 |
|
NCBI chr15:3,648,022...3,651,582
Ensembl chr15:3,643,009...3,651,610
|
|
| G
|
Fut4
|
fucosyltransferase 4
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of FUT4 protein
|
CTD |
PMID:29767511 |
|
NCBI chr 8:19,868,178...19,872,139
Ensembl chr 8:19,868,079...19,872,436
|
|
| G
|
Fut4-ps1
|
fucosyltransferase 4, pseudogene 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of FUT6 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 9:1,656,732...1,659,085
|
|
| G
|
Fut7
|
fucosyltransferase 7
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of FUT7 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 3:28,635,913...28,640,407
Ensembl chr 3:28,637,107...28,641,388
|
|
| G
|
Fut8
|
fucosyltransferase 8
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of FUT8 mRNA
|
CTD |
PMID:35676786 |
|
NCBI chr 6:101,682,354...101,909,784
Ensembl chr 6:101,683,007...101,909,775
|
|
| G
|
Fv1
|
Friend virus susceptibility 1
|
affects expression
|
ISO
|
Arsenic Trioxide affects the expression of C19ORF48P mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr 1:103,867,358...103,873,336
Ensembl chr 1:103,867,373...103,873,342
|
|
| G
|
Fyb1
|
FYN binding protein 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of FYB1 mRNA
|
CTD |
PMID:15761015 |
|
NCBI chr 2:57,360,084...57,508,609
Ensembl chr 2:57,360,096...57,508,608
|
|
| G
|
Fyco1
|
FYVE and coiled-coil domain autophagy adaptor 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of FYCO1 protein
|
CTD |
PMID:25419056 |
|
NCBI chr 8:132,289,538...132,356,810
Ensembl chr 8:132,289,539...132,356,451
|
|
| G
|
Fzd1
|
frizzled class receptor 1
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of FZD1 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 4:30,265,074...30,269,472
Ensembl chr 4:30,247,228...30,833,176
|
|
| G
|
Fzd3
|
frizzled class receptor 3
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of FZD3 mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr15:43,596,962...43,664,047
Ensembl chr15:43,596,965...43,663,960
|
|
| G
|
Fzd5
|
frizzled class receptor 5
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of FZD5 mRNA
|
CTD |
PMID:22521957 |
|
NCBI chr 9:73,606,860...73,614,039
Ensembl chr 9:73,606,860...73,618,612
|
|
| G
|
G0s2
|
G0/G1switch 2
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of G0S2 mRNA
|
CTD |
PMID:29633893 |
|
NCBI chr13:107,335,036...107,335,948
Ensembl chr13:107,335,036...107,336,293
|
|
| G
|
G3bp2
|
G3BP stress granule assembly factor 2
|
multiple interactions decreases expression
|
ISO
|
[Tretinoin co-treated with Arsenic Trioxide] results in decreased expression of G3BP2 protein Arsenic Trioxide results in decreased expression of G3BP2 protein
|
CTD |
PMID:15894607 |
|
NCBI chr14:16,216,684...16,304,828
Ensembl chr14:16,248,744...16,304,823
|
|
| G
|
G6pc1
|
glucose-6-phosphatase catalytic subunit 1
|
increases expression multiple interactions
|
ISO
|
Arsenic Trioxide results in increased expression of G6PC1 mRNA Plant Extracts inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic Trioxide] which results in decreased expression of G6PC1 protein]; Taurine inhibits the reaction [Arsenic Trioxide results in increased expression of G6PC1 mRNA]
|
CTD |
PMID:30362509 PMID:32226249 PMID:35226250 |
|
NCBI chr10:86,807,659...86,819,023
Ensembl chr10:86,757,899...86,818,033
|
|
| G
|
G6pc3
|
glucose 6 phosphatase catalytic subunit 3
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of G6PC3 mRNA
|
CTD |
PMID:25258189 |
|
NCBI chr10:87,647,149...87,651,385
Ensembl chr10:87,647,062...87,653,453
|
|
| G
|
G6pd
|
glucose-6-phosphate dehydrogenase
|
multiple interactions decreases response to substance decreases expression increases expression
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to G6PD protein] G6PD protein results in decreased susceptibility to Arsenic Trioxide Arsenic Trioxide results in decreased expression of G6PD protein Plant Extracts inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic Trioxide] which results in decreased expression of G6PD protein] Arsenic Trioxide results in increased expression of G6PD mRNA
|
CTD |
PMID:20707922 PMID:25419056 PMID:26598702 PMID:32226249 PMID:39716349 |
|
NCBI chr X:157,352,364...157,372,144
Ensembl chr X:157,352,373...157,372,144
|
|
| G
|
Gabarapl2
|
GABA type A receptor associated protein like 2
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of GABARAPL2 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr19:56,819,826...56,830,662
Ensembl chr19:56,819,791...56,830,660
|
|
| G
|
Gabbr1
|
gamma-aminobutyric acid type B receptor subunit 1
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of GABBR1 mRNA
|
CTD |
PMID:18231732 |
|
NCBI chr20:1,469,779...1,499,352
Ensembl chr20:1,469,779...1,498,607
|
|
| G
|
Gabbr2
|
gamma-aminobutyric acid type B receptor subunit 2
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of GABBR2 mRNA Arsenic Trioxide results in decreased expression of GABBR2 mRNA; Arsenic Trioxide results in decreased expression of GABBR2 protein
|
CTD |
PMID:15761015 PMID:37402917 |
|
NCBI chr 5:65,743,073...66,083,695
Ensembl chr 5:65,743,073...66,083,695
|
|
| G
|
Gabpb2
|
GA binding protein transcription factor subunit beta 2
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of GABPB2 mRNA
|
CTD |
PMID:12852829 |
|
NCBI chr 2:185,444,309...185,484,200
Ensembl chr 2:185,450,296...185,483,589
|
|
| G
|
Gabra1
|
gamma-aminobutyric acid type A receptor subunit alpha 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of GABRA1 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr10:27,096,731...27,152,563
Ensembl chr10:27,096,740...27,152,442
|
|
| G
|
Gabrb3
|
gamma-aminobutyric acid type A receptor subunit beta 3
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of GABRB3 mRNA
|
CTD |
PMID:26705709 |
|
NCBI chr 1:117,602,772...117,838,230
Ensembl chr 1:117,431,842...117,836,725
|
|
| G
|
Gabre
|
gamma-aminobutyric acid type A receptor subunit epsilon
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of GABRE mRNA
|
CTD |
PMID:22521957 |
|
NCBI chr X:155,102,078...155,120,821
Ensembl chr X:155,102,083...155,120,735
|
|
| G
|
Gabrr1
|
gamma-aminobutyric acid type A receptor subunit rho 1
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of GABRR1 mRNA
|
CTD |
PMID:26705709 |
|
NCBI chr 5:52,320,475...52,357,549
Ensembl chr 5:52,320,475...52,357,549
|
|
| G
|
Gad2
|
glutamate decarboxylase 2
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of GAD2 mRNA; Arsenic Trioxide results in decreased expression of GAD2 protein
|
CTD |
PMID:37402917 |
|
NCBI chr17:89,671,718...89,734,246
Ensembl chr17:89,671,716...89,941,089
|
|
| G
|
Gadd45a
|
growth arrest and DNA-damage-inducible, alpha
|
decreases methylation increases expression decreases expression affects expression multiple interactions
|
ISO EXP
|
Arsenic Trioxide results in decreased methylation of GADD45A promoter Arsenic Trioxide results in increased expression of GADD45A mRNA; Arsenic Trioxide results in increased expression of GADD45A protein Arsenic Trioxide results in decreased expression of GADD45A mRNA Arsenic Trioxide affects the expression of GADD45A mRNA Atrazine promotes the reaction [Arsenic Trioxide results in increased expression of GADD45A mRNA]
|
CTD |
PMID:11678611 PMID:15493360 PMID:15761015 PMID:17374990 PMID:17530438 PMID:19730151 PMID:20458559 PMID:26705709 PMID:29159499 PMID:29633893 PMID:29767511 More...
|
|
NCBI chr 4:97,484,497...97,486,799
Ensembl chr 4:97,484,502...97,486,807
|
|
| G
|
Gadd45b
|
growth arrest and DNA-damage-inducible, beta
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of GADD45B mRNA
|
CTD |
PMID:25258189 |
|
NCBI chr 7:9,428,689...9,430,991
Ensembl chr 7:9,428,689...9,430,718
|
|
| G
|
Gak
|
cyclin G associated kinase
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of GAK mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr14:1,234,272...1,308,492
Ensembl chr14:1,234,266...1,323,974
|
|
| G
|
Gale
|
UDP-galactose-4-epimerase
|
multiple interactions increases expression
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to GALE protein] Arsenic Trioxide results in increased expression of GALE protein
|
CTD |
PMID:19364129 PMID:26598702 |
|
NCBI chr 5:153,477,420...153,481,926
Ensembl chr 5:153,478,325...153,481,922
|
|
| G
|
Galk1
|
galactokinase 1
|
increases expression multiple interactions
|
ISO
|
Arsenic Trioxide results in increased expression of GALK1 protein Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to GALK1 protein]
|
CTD |
PMID:19364129 PMID:26598702 |
|
NCBI chr10:101,742,067...101,746,244
Ensembl chr10:101,735,061...101,746,258
|
|
| G
|
Galk2
|
galactokinase 2
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to GALK2 protein]
|
CTD |
PMID:26598702 |
|
NCBI chr 3:133,563,524...133,696,423
Ensembl chr 3:133,563,538...133,696,528
|
|
| G
|
Galm
|
galactose mutarotase
|
multiple interactions
|
ISO
|
[Tretinoin co-treated with Arsenic Trioxide] results in increased expression of GALM mRNA
|
CTD |
PMID:15894607 |
|
NCBI chr 6:20,589,775...20,641,516
Ensembl chr 6:20,589,776...20,644,417
|
|
| G
|
Galnt12
|
polypeptide N-acetylgalactosaminyltransferase 12
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of GALNT12 mRNA
|
CTD |
PMID:19128835 |
|
NCBI chr 5:66,180,171...66,208,931
Ensembl chr 5:66,180,164...66,208,938
|
|
| G
|
Galnt18
|
polypeptide N-acetylgalactosaminyltransferase 18
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of GALNT18 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 1:175,027,832...175,338,883
Ensembl chr 1:175,027,839...175,338,883
|
|
| G
|
Galnt3
|
polypeptide N-acetylgalactosaminyltransferase 3
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of GALNT3 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 3:71,150,559...71,187,321
Ensembl chr 3:71,150,571...71,174,323
|
|
| G
|
Ganab
|
glucosidase II alpha subunit
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of GANAB protein
|
CTD |
PMID:19364129 |
|
NCBI chr 1:215,222,918...215,242,808
Ensembl chr 1:215,222,995...215,243,036
|
|
| G
|
Gap43
|
growth associated protein 43
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of GAP43 mRNA
|
CTD |
PMID:26705709 |
|
NCBI chr11:71,882,131...71,975,799
Ensembl chr11:71,882,131...71,975,797
|
|
| G
|
Gapdh
|
glyceraldehyde-3-phosphate dehydrogenase
|
decreases activity multiple interactions increases expression decreases expression
|
ISO
|
Arsenic Trioxide results in decreased activity of GAPDH protein [Ascorbic Acid co-treated with Arsenic Trioxide] results in decreased expression of GAPDH protein; Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to GAPDH protein]; Arsenic Trioxide promotes the reaction [Ascorbic Acid results in decreased expression of GAPDH mRNA]; Ascorbic Acid promotes the reaction [Arsenic Trioxide results in decreased expression of GAPDH mRNA]; Ascorbic Acid promotes the reaction [Arsenic Trioxide results in decreased expression of GAPDH protein] Arsenic Trioxide results in increased expression of GAPDH mRNA Arsenic Trioxide results in decreased expression of GAPDH mRNA; Arsenic Trioxide results in decreased expression of GAPDH protein
|
CTD |
PMID:15916724 PMID:26598702 PMID:35676786 PMID:38160894 |
|
NCBI chr 4:159,648,592...159,653,436
Ensembl chr 4:159,648,592...159,653,377
|
|
| G
|
Garem1
|
GRB2 associated regulator of MAPK1 subtype 1
|
decreases expression increases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of GAREM mRNA Arsenic Trioxide results in increased expression of GAREM1 mRNA
|
CTD |
PMID:26705709 PMID:39716349 |
|
NCBI chr18:12,695,082...12,860,219
Ensembl chr18:12,695,082...12,860,219
|
|
| G
|
Garnl3
|
GTPase activating Rap/RanGAP domain-like 3
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of GARNL3 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 3:36,686,388...36,830,011
Ensembl chr 3:36,686,389...36,830,020
|
|
| G
|
Gars1
|
glycyl-tRNA synthetase 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of GARS1 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 4:85,484,939...85,542,876
Ensembl chr 4:85,493,753...85,542,876
|
|
| G
|
Gart
|
phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase
|
decreases expression increases expression multiple interactions
|
ISO
|
Arsenic Trioxide results in decreased expression of GART protein Arsenic Trioxide results in increased expression of GART mRNA; Arsenic Trioxide results in increased expression of GART protein Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to GART protein]
|
CTD |
PMID:19364129 PMID:22521957 PMID:25419056 PMID:26598702 |
|
NCBI chr11:44,351,841...44,377,086
Ensembl chr11:44,351,851...44,377,086
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| G
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Gas1
|
growth arrest-specific 1
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of GAS1 mRNA
|
CTD |
PMID:26705709 |
|
NCBI chr17:4,487,716...4,490,701
Ensembl chr17:4,484,283...4,497,657
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|
| G
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Gas2
|
growth arrest-specific 2
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to GAS2 protein]
|
CTD |
PMID:26598702 |
|
NCBI chr 1:110,587,952...110,721,572
Ensembl chr 1:110,717,312...110,718,541
|
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| G
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Gas7
|
growth arrest specific 7
|
multiple interactions
|
ISO
|
[Tretinoin co-treated with Arsenic Trioxide] results in increased expression of GAS7 mRNA
|
CTD |
PMID:15894607 |
|
NCBI chr10:52,651,690...52,882,244
Ensembl chr10:52,651,690...52,882,244
|
|
| G
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Gata1
|
GATA binding protein 1
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of GATA1 protein
|
CTD |
PMID:16360329 |
|
NCBI chr X:17,193,291...17,209,462
Ensembl chr X:17,201,633...17,209,459
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|
| G
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Gata2
|
GATA binding protein 2
|
affects methylation increases expression
|
ISO
|
Arsenic Trioxide affects the methylation of GATA2 promoter Arsenic Trioxide results in increased expression of GATA2 protein
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CTD |
PMID:16360329 PMID:26046465 |
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NCBI chr 4:122,211,501...122,225,058
Ensembl chr 4:122,211,829...122,225,055
|
|
| G
|
Gata3
|
GATA binding protein 3
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [GATA3 protein binds to IL13 promoter]; Arsenic Trioxide inhibits the reaction [GATA3 protein binds to KPNA2 protein]
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CTD |
PMID:19080345 |
|
NCBI chr17:73,544,234...73,575,670
Ensembl chr17:73,553,548...73,575,670
|
|
| G
|
Gata4
|
GATA binding protein 4
|
increases expression
|
ISO EXP
|
Arsenic Trioxide results in increased expression of GATA4 mRNA Arsenic Trioxide results in increased expression of GATA4 protein
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CTD |
PMID:29767511 PMID:31734849 |
|
NCBI chr15:41,635,572...41,707,252
Ensembl chr15:41,635,572...41,681,609
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|
| G
|
Gata6
|
GATA binding protein 6
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of GATA6 mRNA
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CTD |
PMID:29767511 |
|
NCBI chr18:2,460,909...2,492,322
Ensembl chr18:2,458,253...2,492,322
|
|
| G
|
Gba1
|
glucosylceramidase beta 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of GBA1 mRNA
|
CTD |
PMID:15761015 |
|
NCBI chr 2:176,902,141...176,916,015
Ensembl chr 2:176,907,154...176,916,985
|
|
| G
|
Gbe1
|
1,4-alpha-glucan branching enzyme 1
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of GBE1 mRNA
|
CTD |
PMID:35676786 |
|
NCBI chr11:22,181,194...22,446,640
Ensembl chr11:22,181,103...22,446,638
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|
| G
|
Gbp5
|
guanylate binding protein 5
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to GBP5 protein]
|
CTD |
PMID:26598702 |
|
NCBI chr 2:233,910,999...233,930,320
Ensembl chr 2:233,902,113...233,930,826
|
|
| G
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Gca
|
grancalcin
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of GCA mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr 3:67,705,874...67,738,475
Ensembl chr 3:67,705,890...67,737,387
|
|
| G
|
Gcc2
|
GRIP and coiled-coil domain containing 2
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of GCC2 mRNA
|
CTD |
PMID:22521957 |
|
NCBI chr20:26,788,472...26,836,728
Ensembl chr20:26,790,516...26,836,726
|
|
| G
|
Gck
|
glucokinase
|
multiple interactions decreases expression
|
ISO
|
Plant Extracts inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic Trioxide] which results in decreased activity of GCK protein]; Taurine inhibits the reaction [Arsenic Trioxide results in decreased expression of GCK mRNA] Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to GCK protein]
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CTD |
PMID:26598702 PMID:30362509 PMID:32226249 |
|
NCBI chr14:84,999,019...85,041,098
Ensembl chr14:84,999,020...85,040,949
|
|
| G
|
Gclc
|
glutamate-cysteine ligase, catalytic subunit
|
decreases response to substance increases expression decreases expression multiple interactions
|
ISO
|
GCLC protein results in decreased susceptibility to Arsenic Trioxide Arsenic Trioxide results in increased expression of GCLC mRNA Arsenic Trioxide results in decreased expression of GCLC protein Arsenic Trioxide results in increased expression of GCLC mRNA; Arsenic Trioxide results in increased expression of GCLC protein NFE2L2 protein affects the reaction [Arsenic Trioxide results in increased expression of GCLC mRNA] [Arsenic Trioxide results in increased abundance of Arsenic] which results in increased expression of GCLC mRNA; [Arsenic Trioxide results in increased abundance of Arsenic] which results in increased expression of GCLC protein
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CTD |
PMID:19417148 PMID:20707922 PMID:22521957 PMID:23426167 PMID:25341331 PMID:25419056 PMID:29049341 PMID:29549912 PMID:33434570 More...
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|
NCBI chr 8:87,510,251...87,548,896
Ensembl chr 8:87,510,463...87,548,893
|
|
| G
|
Gclm
|
glutamate cysteine ligase, modifier subunit
|
multiple interactions increases expression decreases expression
|
ISO
|
[Arsenic Trioxide results in increased abundance of Arsenic] which results in increased expression of GCLM mRNA; [Arsenic Trioxide results in increased abundance of Arsenic] which results in increased expression of GCLM protein; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased expression of GCLM mRNA]; Arsenic Trioxide promotes the reaction [nilotinib results in increased expression of GCLM mRNA]; Ethionamide inhibits the reaction [Arsenic Trioxide results in increased expression of GCLM mRNA] Arsenic Trioxide results in decreased expression of GCLM protein
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CTD |
PMID:15725085 PMID:19128835 PMID:19350554 PMID:19417148 PMID:23883479 PMID:25003661 PMID:25341331 PMID:26705709 PMID:26708503 PMID:27829220 PMID:33434570 PMID:39716349 More...
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|
NCBI chr 2:213,032,135...213,052,192
Ensembl chr 2:213,031,838...213,055,003
|
|
| G
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Gcnt3
|
glucosaminyl (N-acetyl) transferase 3, mucin type
|
decreases response to substance multiple interactions decreases expression increases expression
|
ISO
|
GCNT3 protein results in decreased susceptibility to Arsenic Trioxide Metformin inhibits the reaction [Arsenic Trioxide results in increased expression of GCNT3 mRNA] Arsenic Trioxide results in decreased expression of GCNT3 mRNA
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CTD |
PMID:20707922 PMID:21461292 PMID:29095437 |
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NCBI chr 8:79,570,081...79,577,389
Ensembl chr 8:79,566,753...79,581,595
|
|
| G
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Gda
|
guanine deaminase
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of GDA mRNA
|
CTD |
PMID:21461292 PMID:27829220 |
|
NCBI chr 1:228,333,401...228,408,901
Ensembl chr 1:228,333,364...228,409,348
|
|
| G
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Gde1
|
glycerophosphodiester phosphodiesterase 1
|
decreases response to substance
|
ISO
|
GDE1 protein results in decreased susceptibility to Arsenic Trioxide
|
CTD |
PMID:20707922 |
|
NCBI chr 1:182,451,182...182,466,569
Ensembl chr 1:182,451,184...182,466,772
|
|
| G
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Gdf15
|
growth differentiation factor 15
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increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of GDF15 mRNA
|
CTD |
PMID:19036111 PMID:25258189 PMID:26705709 PMID:27829220 |
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NCBI chr16:18,838,436...18,842,022
Ensembl chr16:18,838,436...18,842,022
|
|
| G
|
Gdi1
|
GDP dissociation inhibitor 1
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to GDI1 protein]
|
CTD |
PMID:26598702 |
|
NCBI chr X:157,238,900...157,245,562
Ensembl chr X:157,238,892...157,245,560
|
|
| G
|
Gdi2
|
GDP dissociation inhibitor 2
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to GDI2 protein]
|
CTD |
PMID:26598702 |
|
NCBI chr17:71,559,460...71,586,147
Ensembl chr17:71,559,461...71,586,147
|
|
| G
|
Gdnf
|
glial cell derived neurotrophic factor
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of GDNF mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 2:58,621,327...58,647,242
Ensembl chr 2:58,621,327...58,647,240
|
|
| G
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Get3
|
guided entry of tail-anchored proteins factor 3, ATPase
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of GET3 mRNA; Arsenic Trioxide results in increased expression of GET3 protein
|
CTD |
PMID:27736728 |
|
NCBI chr19:40,034,675...40,043,064
Ensembl chr19:40,034,967...40,043,061
|
|
| G
|
Gfod1
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Gfo/Idh/MocA-like oxidoreductase domain containing 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of GFOD1 mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr17:21,606,090...21,710,922
Ensembl chr17:21,605,415...21,710,920
|
|
| G
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Gfus
|
GDP-L-fucose synthase
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to GFUS protein]
|
CTD |
PMID:26598702 |
|
NCBI chr 7:109,492,808...109,497,719
Ensembl chr 7:109,492,809...109,497,662
|
|
| G
|
Gga1
|
golgi associated, gamma adaptin ear containing, ARF binding protein 1
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to GGA1 protein]
|
CTD |
PMID:26598702 |
|
NCBI chr 7:112,316,530...112,332,249
Ensembl chr 7:112,315,449...112,332,249
|
|
| G
|
Gga3
|
golgi associated, gamma adaptin ear containing, ARF binding protein 3
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to GGA3 protein]
|
CTD |
PMID:26598702 |
|
NCBI chr10:101,324,378...101,342,373
Ensembl chr10:101,324,378...101,342,373
|
|
| G
|
Ggh
|
gamma-glutamyl hydrolase
|
increases expression decreases expression
|
ISO
|
Arsenic Trioxide results in increased expression of GGH mRNA Arsenic Trioxide results in decreased expression of GGH mRNA
|
CTD |
PMID:25258189 PMID:39716349 |
|
NCBI chr 5:38,326,747...38,349,655
Ensembl chr 5:38,326,594...38,349,647
|
|
| G
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Ggt1
|
gamma-glutamyltransferase 1
|
multiple interactions increases secretion
|
EXP
|
Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased secretion of GGT1 protein]
|
CTD |
PMID:24634002 |
|
NCBI chr20:13,074,141...13,103,551
Ensembl chr20:13,074,141...13,088,050
|
|
| G
|
Gh1
|
growth hormone 1
|
multiple interactions increases response to substance decreases expression
|
ISO EXP
|
GH1 protein promotes the reaction [Arsenic Trioxide results in decreased activity of MMP9 protein]; GH1 protein promotes the reaction [Arsenic Trioxide results in decreased expression of BCL2 mRNA]; GH1 protein promotes the reaction [Arsenic Trioxide results in decreased expression of BIRC5 mRNA]; GH1 protein promotes the reaction [Arsenic Trioxide results in decreased expression of CDH1 mRNA]; GH1 protein promotes the reaction [Arsenic Trioxide results in decreased expression of MMP2 mRNA]; GH1 protein promotes the reaction [Arsenic Trioxide results in decreased expression of MMP9 mRNA]; GH1 protein promotes the reaction [Arsenic Trioxide results in decreased expression of PLAU mRNA]; GH1 protein promotes the reaction [Arsenic Trioxide results in decreased expression of PLAUR mRNA]; GH1 protein promotes the reaction [Arsenic Trioxide results in decreased expression of TERT mRNA]; GH1 protein promotes the reaction [Arsenic Trioxide results in increased expression of BAX mRNA]; GH1 protein promotes the reaction [Arsenic Trioxide results in increased expression of CDKN2A mRNA]; GH1 protein promotes the reaction [Arsenic Trioxide results in increased expression of MYC mRNA]; GH1 protein promotes the reaction [Arsenic Trioxide results in increased expression of PMAIP1 mRNA]; GH1 protein promotes the reaction [Arsenic Trioxide results in increased expression of TP53 mRNA] GH1 protein results in increased susceptibility to Arsenic Trioxide Arsenic Trioxide results in decreased expression of GH1 protein
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CTD |
PMID:23851143 PMID:31258454 |
|
NCBI chr10:91,727,883...91,729,860
Ensembl chr10:91,727,884...91,729,859
|
|
| G
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Gigyf2
|
GRB10 interacting GYF protein 2
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of GIGYF2 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 9:95,449,143...95,574,927
Ensembl chr 9:95,449,167...95,574,927
|
|
| G
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Gimap6
|
GTPase, IMAP family member 6
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of GIMAP6 mRNA
|
CTD |
PMID:15761015 |
|
NCBI chr 4:78,984,597...78,990,006
Ensembl chr 4:78,983,504...78,990,010
|
|
| G
|
Gimd1
|
GIMAP family P-loop NTPase domain containing 1
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of GIMD1 mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr 2:223,777,876...223,812,582
Ensembl chr 2:223,777,889...223,812,576
|
|
| G
|
Gipc1
|
GIPC PDZ domain containing family, member 1
|
decreases response to substance
|
ISO
|
GIPC1 protein results in decreased susceptibility to Arsenic Trioxide
|
CTD |
PMID:20707922 |
|
NCBI chr19:41,380,125...41,392,078
Ensembl chr19:41,380,125...41,391,725
|
|
| G
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Git2
|
GIT ArfGAP 2
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of GIT2 mRNA
|
CTD |
PMID:15761015 |
|
NCBI chr12:47,490,350...47,531,232
Ensembl chr12:47,490,369...47,533,250
|
|
| G
|
Gja1
|
gap junction protein, alpha 1
|
decreases expression multiple interactions
|
ISO
|
Arsenic Trioxide results in decreased expression of GJA1 mRNA acetylleucyl-leucyl-norleucinal inhibits the reaction [Arsenic Trioxide results in decreased expression of GJA1 mRNA]; leupeptin inhibits the reaction [Arsenic Trioxide results in decreased expression of GJA1 mRNA]
|
CTD |
PMID:15070760 PMID:15761015 PMID:17559834 |
|
NCBI chr20:36,302,490...36,315,010
Ensembl chr20:36,302,352...36,319,689
|
|
| G
|
Gja4
|
gap junction protein, alpha 4
|
decreases expression
|
EXP
|
Arsenic Trioxide results in decreased expression of GJA4 protein
|
CTD |
PMID:17559834 |
|
NCBI chr 5:144,917,791...144,920,324
Ensembl chr 5:144,914,147...144,921,216
|
|
| G
|
Gja5
|
gap junction protein, alpha 5
|
decreases expression
|
EXP
|
Arsenic Trioxide results in decreased expression of GJA5 protein
|
CTD |
PMID:17559834 |
|
NCBI chr 2:187,291,227...187,310,770
Ensembl chr 2:187,234,674...187,318,512
|
|
| G
|
Gja8
|
gap junction protein, alpha 8
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of GJA8 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 2:187,179,668...187,181,284
Ensembl chr 2:187,175,507...187,186,167
|
|
| G
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Gjb3
|
gap junction protein, beta 3
|
decreases response to substance
|
ISO
|
GJB3 protein results in decreased susceptibility to Arsenic Trioxide
|
CTD |
PMID:20707922 |
|
NCBI chr 5:144,933,692...144,939,435
Ensembl chr 5:144,933,696...144,940,280
|
|
| G
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Gkn1
|
gastrokine 1
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to GKN1 protein]
|
CTD |
PMID:26598702 |
|
NCBI chr 4:121,347,417...121,352,705
Ensembl chr 4:121,347,417...121,352,830
|
|
| G
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Gla
|
galactosidase, alpha
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of GLA mRNA
|
CTD |
PMID:17547211 |
|
NCBI chr X:102,062,497...102,073,915
Ensembl chr X:102,056,718...102,073,915
|
|
| G
|
Glb1
|
galactosidase, beta 1
|
increases activity increases expression multiple interactions
|
ISO EXP
|
Arsenic Trioxide results in increased activity of GLB1 protein Arsenic Trioxide results in increased expression of GLB1 protein pyrazolanthrone inhibits the reaction [Arsenic Trioxide results in increased activity of GLB1 protein]; pyrazolanthrone promotes the reaction [SB 203580 inhibits the reaction [Arsenic Trioxide results in increased activity of GLB1 protein]]; SB 203580 inhibits the reaction [Arsenic Trioxide results in increased activity of GLB1 protein]; SB 203580 promotes the reaction [pyrazolanthrone inhibits the reaction [Arsenic Trioxide results in increased activity of GLB1 protein]]
|
CTD |
PMID:31734849 PMID:36801614 |
|
NCBI chr 8:122,963,718...123,036,326
Ensembl chr 8:122,963,718...123,036,326
|
|
| G
|
Gli1
|
GLI family zinc finger 1
|
decreases expression increases response to substance multiple interactions
|
ISO EXP
|
Arsenic Trioxide results in decreased expression of GLI1 mRNA; Arsenic Trioxide results in decreased expression of GLI1 protein GLI1 protein results in increased susceptibility to Arsenic Trioxide [Arsenic Trioxide co-treated with Curcumin] inhibits the reaction [Cisplatin results in increased expression of GLI1 protein]; Arsenic Trioxide inhibits the reaction [Cisplatin results in increased expression of GLI1 protein] Arsenic Trioxide inhibits the reaction [pralsetinib results in increased expression of GLI1 protein]
|
CTD |
PMID:21183792 PMID:23861973 PMID:25945059 PMID:30983542 PMID:31612257 PMID:37301138 PMID:38130211 More...
|
|
NCBI chr 7:65,042,237...65,054,888
Ensembl chr 7:65,042,237...65,054,540
|
|
| G
|
Gli2
|
GLI family zinc finger 2
|
increases response to substance decreases expression decreases response to substance multiple interactions increases expression
|
ISO EXP
|
GLI2 protein results in increased susceptibility to Arsenic Trioxide Arsenic Trioxide results in decreased expression of GLI2 mRNA GLI2 protein results in decreased susceptibility to Arsenic Trioxide Arsenic Trioxide inhibits the reaction [Cisplatin results in increased expression of GLI2 protein]; Curcumin promotes the reaction [Arsenic Trioxide inhibits the reaction [Cisplatin results in increased expression of GLI2 protein]] Arsenic Trioxide results in increased expression of GLI2 mRNA
|
CTD |
PMID:20707922 PMID:21183792 PMID:23861973 PMID:24685274 PMID:25945059 PMID:31612257 PMID:38130211 PMID:39716349 More...
|
|
NCBI chr13:32,499,678...32,716,418
Ensembl chr13:32,499,678...32,716,418
|
|
| G
|
Gli3
|
GLI family zinc finger 3
|
multiple interactions
|
ISO
|
Arsenic Trioxide promotes the reaction [[GLI3 protein binds to KIT promoter] which results in decreased expression of KIT mRNA]; Arsenic Trioxide promotes the reaction [GLI3 protein binds to KIT promoter]
|
CTD |
PMID:27793025 |
|
NCBI chr17:54,134,064...54,405,198
Ensembl chr17:54,134,064...54,405,198
|
|
| G
|
Glipr1
|
GLI pathogenesis-related 1
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of GLIPR1 mRNA
|
CTD |
PMID:19128835 |
|
NCBI chr 7:49,373,579...49,399,190
Ensembl chr 7:49,373,581...49,384,640
|
|
| G
|
Glo1
|
glyoxalase 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of GLO1 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr20:8,665,061...8,683,095
Ensembl chr20:8,665,061...8,683,191
|
|
| G
|
Glrx3
|
glutaredoxin 3
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of GLRX3 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 1:201,671,410...201,701,722
Ensembl chr 1:201,671,481...201,701,717
|
|
| G
|
Gls
|
glutaminase
|
increases expression decreases response to substance
|
ISO
|
Arsenic Trioxide results in increased expression of GLS mRNA GLS protein results in decreased susceptibility to Arsenic Trioxide
|
CTD |
PMID:20458559 PMID:24276018 |
|
NCBI chr 9:56,836,584...56,908,861
Ensembl chr 9:56,836,584...56,908,861
|
|
| G
|
Gls2
|
glutaminase 2
|
affects response to substance
|
ISO
|
GLS2 protein affects the susceptibility to Arsenic Trioxide
|
CTD |
PMID:24276018 |
|
NCBI chr 7:1,201,757...1,218,014
Ensembl chr 7:1,201,838...1,218,013
|
|
| G
|
Glt6d1
|
glycosyltransferase 6 domain containing 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of GLT6D1 mRNA
|
CTD |
PMID:21461292 |
|
NCBI chr 3:29,026,023...29,037,010
Ensembl chr 3:29,026,025...29,036,699
|
|
| G
|
Gltp
|
glycolipid transfer protein
|
decreases expression multiple interactions
|
ISO
|
Arsenic Trioxide results in decreased expression of GLTP mRNA Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to GLTP protein]
|
CTD |
PMID:20458559 PMID:26598702 |
|
NCBI chr12:47,567,797...47,587,949
Ensembl chr12:47,567,770...47,587,946
|
|
| G
|
Glud1
|
glutamate dehydrogenase 1
|
increases expression decreases expression
|
ISO
|
Arsenic Trioxide results in increased expression of GLUD1 protein Arsenic Trioxide results in decreased expression of GLUD1 protein
|
CTD |
PMID:19364129 PMID:25419056 |
|
NCBI chr16:9,646,569...9,680,215
Ensembl chr16:9,646,509...9,680,210
|
|
| G
|
Glul
|
glutamate-ammonia ligase
|
multiple interactions increases expression
|
ISO
|
[Tretinoin co-treated with Arsenic Trioxide] results in increased expression of GLUL mRNA; Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to GLUL protein] Arsenic Trioxide results in increased expression of GLUL mRNA
|
CTD |
PMID:15894607 PMID:26598702 |
|
NCBI chr13:68,519,500...68,585,554
Ensembl chr13:68,576,067...68,585,520
|
|
| G
|
Gmps
|
guanine monophosphate synthase
|
increases expression decreases expression multiple interactions
|
ISO
|
Arsenic Trioxide results in increased expression of GMPS protein Arsenic Trioxide results in decreased expression of GMPS protein Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to GMPS protein]
|
CTD |
PMID:19364129 PMID:25419056 PMID:26598702 |
|
NCBI chr 2:150,587,824...150,641,564
Ensembl chr 2:150,587,854...150,648,986
|
|
| G
|
Gna11
|
G protein subunit alpha 11
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of GNA11 mRNA
|
CTD |
PMID:22521957 |
|
NCBI chr 7:8,814,285...8,828,628
Ensembl chr 7:8,814,327...8,830,558
|
|
| G
|
Gnai3
|
G protein subunit alpha i3
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of GNAI3 protein
|
CTD |
PMID:25419056 |
|
NCBI chr 2:198,430,920...198,468,874
|
|
| G
|
Gnal
|
G protein subunit alpha L
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of GNAL mRNA
|
CTD |
PMID:15761015 |
|
NCBI chr18:62,892,257...63,032,510
Ensembl chr18:62,892,226...63,043,129
|
|
| G
|
Gne
|
glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of GNE mRNA
|
CTD |
PMID:27829220 |
|
NCBI chr 5:63,062,953...63,103,320
Ensembl chr 5:63,062,850...63,103,251
|
|
| G
|
Golga2
|
golgin A2
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of GOLGA2 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 3:35,981,783...36,002,023
Ensembl chr 3:35,981,499...36,002,022
|
|
| G
|
Golph3
|
golgi phosphoprotein 3
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to GOLPH3 protein]
|
CTD |
PMID:26598702 |
|
NCBI chr 2:63,072,610...63,103,091
Ensembl chr 2:63,074,256...63,113,577
|
|
| G
|
Gopc
|
golgi associated PDZ and coiled-coil motif containing
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to GOPC protein]
|
CTD |
PMID:26598702 |
|
NCBI chr20:32,270,314...32,319,635
Ensembl chr20:32,270,314...32,319,611
|
|
| G
|
Got1
|
glutamic-oxaloacetic transaminase 1
|
decreases expression increases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of GOT1 protein Arsenic Trioxide results in increased expression of GOT1 mRNA
|
CTD |
PMID:19364129 PMID:20458559 |
|
NCBI chr 1:252,306,541...252,337,622
Ensembl chr 1:252,284,434...252,329,871
|
|
| G
|
Got2
|
glutamic-oxaloacetic transaminase 2
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of GOT2 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr19:9,180,428...9,206,113
Ensembl chr19:9,180,431...9,206,111
|
|
| G
|
Gpc1
|
glypican 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of GPC1 mRNA
|
CTD |
PMID:25555879 |
|
NCBI chr 9:100,843,645...100,871,458
Ensembl chr 9:100,843,645...100,879,933
|
|
| G
|
Gpc3
|
glypican 3
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of GPC3 protein
|
CTD |
PMID:33634982 |
|
NCBI chr X:136,789,770...137,157,598
Ensembl chr X:136,789,770...137,157,639
|
|
| G
|
Gpc4
|
glypican 4
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of GPC4 mRNA
|
CTD |
PMID:19128835 |
|
NCBI chr X:136,565,536...136,676,142
Ensembl chr X:136,565,591...136,676,057
|
|
| G
|
Gpc6
|
glypican 6
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of GPC6 mRNA
|
CTD |
PMID:25258189 |
|
NCBI chr15:100,437,415...101,435,038
Ensembl chr15:100,437,943...101,435,027
|
|
| G
|
Gpd1
|
glycerol-3-phosphate dehydrogenase 1
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to GPD1 protein]
|
CTD |
PMID:26598702 |
|
NCBI chr 7:132,722,982...132,730,373
Ensembl chr 7:132,721,915...132,730,368
|
|
| G
|
Gpd2
|
glycerol-3-phosphate dehydrogenase 2
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of GPD2 mRNA
|
CTD |
PMID:22521957 |
|
NCBI chr 3:62,209,432...62,346,590
Ensembl chr 3:62,210,814...62,346,593
|
|
| G
|
Gper1
|
G protein-coupled estrogen receptor 1
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of GPER1 mRNA
|
CTD |
PMID:17547211 PMID:19128835 |
|
NCBI chr12:20,331,073...20,336,527
Ensembl chr12:20,327,679...20,337,144
|
|
| G
|
Gpi
|
glucose-6-phosphate isomerase
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of GPI mRNA
|
CTD |
PMID:22521957 |
|
NCBI chr 1:95,965,389...95,996,932
Ensembl chr 1:95,965,396...95,993,261
|
|
| G
|
Gpkow
|
G patch domain and KOW motifs
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to GPKOW protein]
|
CTD |
PMID:26598702 |
|
NCBI chr X:17,463,521...17,478,298
Ensembl chr X:17,463,525...17,478,298
|
|
| G
|
Gpm6a
|
glycoprotein m6a
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of GPM6A mRNA
|
CTD |
PMID:15761015 |
|
NCBI chr16:43,374,385...43,706,461
Ensembl chr16:43,374,385...43,706,705
|
|
| G
|
Gpm6b
|
glycoprotein m6b
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of GPM6B mRNA
|
CTD |
PMID:26705709 |
|
NCBI chr X:31,689,485...31,836,199
Ensembl chr X:31,690,359...31,733,272
|
|
| G
|
Gpn1
|
GPN-loop GTPase 1
|
decreases expression multiple interactions
|
ISO
|
Arsenic Trioxide results in decreased expression of GPN1 mRNA [Arsenic Trioxide co-treated with Ascorbic Acid] results in decreased expression of GPN1 mRNA
|
CTD |
PMID:25555879 |
|
NCBI chr 6:30,667,337...30,685,011
Ensembl chr 6:30,666,868...30,685,011
|
|
| G
|
Gpn3
|
GPN-loop GTPase 3
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of GPN3 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr12:39,850,070...39,859,032
Ensembl chr12:39,850,070...39,859,032
|
|
| G
|
Gpnmb
|
glycoprotein nmb
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of GPNMB mRNA
|
CTD |
PMID:26705709 PMID:27829220 |
|
NCBI chr 4:79,341,128...79,362,366
Ensembl chr 4:79,341,021...79,380,240
|
|
| G
|
Gpr119
|
G protein-coupled receptor 119
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to GPR119 protein]
|
CTD |
PMID:26598702 |
|
NCBI chr X:132,730,027...132,736,080
Ensembl chr X:132,730,027...132,736,080
|
|
| G
|
Gpr15
|
G protein-coupled receptor 15
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of GPR15 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr11:55,367,496...55,368,842
Ensembl chr11:55,358,614...55,374,150
|
|
| G
|
Gpr17
|
G protein-coupled receptor 17
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of GPR17 mRNA
|
CTD |
PMID:24356939 |
|
NCBI chr18:23,850,460...23,857,381
Ensembl chr18:23,850,107...23,857,702
|
|
| G
|
Gpr174
|
G protein-coupled receptor 174
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of GPR174 mRNA
|
CTD |
PMID:27829220 |
|
NCBI chr X:76,428,274...76,469,020
Ensembl chr X:76,377,973...76,468,985
|
|
| G
|
Gpr18
|
G protein-coupled receptor 18
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of GPR18 mRNA
|
CTD |
PMID:23824090 PMID:24356939 PMID:25424538 |
|
NCBI chr15:105,404,062...105,407,812
Ensembl chr15:105,404,077...105,408,836
|
|
| G
|
Gpr183
|
G protein-coupled receptor 183
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of GPR183 mRNA
|
CTD |
PMID:15761015 |
|
NCBI chr15:105,445,129...105,457,192
Ensembl chr15:105,437,561...105,466,977
|
|
| G
|
Gpr37
|
G protein-coupled receptor 37
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of GPR37 mRNA
|
CTD |
PMID:26705709 |
|
NCBI chr 4:55,104,355...55,126,420
Ensembl chr 4:55,104,365...55,126,494
|
|
| G
|
Gpr75
|
G protein-coupled receptor 75
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of GPR75 mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr14:108,810,462...108,821,926
Ensembl chr14:108,817,086...108,821,926
|
|
| G
|
Gpr87
|
G protein-coupled receptor 87
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of GPR87 mRNA
|
CTD |
PMID:26705709 |
|
NCBI chr 2:145,589,630...145,608,094
Ensembl chr 2:145,589,569...145,604,442
|
|
| G
|
Gprasp1
|
G protein-coupled receptor associated sorting protein 1
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of GPRASP1 mRNA
|
CTD |
PMID:35676786 |
|
NCBI chr X:103,556,493...103,564,275
Ensembl chr X:103,501,377...103,565,649
|
|
| G
|
Gprc5a
|
G protein-coupled receptor, class C, group 5, member A
|
decreases response to substance
|
ISO
|
GPRC5A protein results in decreased susceptibility to Arsenic Trioxide
|
CTD |
PMID:20707922 |
|
NCBI chr 4:169,634,896...169,653,627
Ensembl chr 4:169,634,748...169,653,625
|
|
| G
|
Gprc5d
|
G protein-coupled receptor, class C, group 5, member D
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of GPRC5D mRNA
|
CTD |
PMID:15725085 |
|
NCBI chr 4:169,674,874...169,686,965
Ensembl chr 4:169,674,846...169,686,965
|
|
| G
|
Gpsm3
|
G-protein signaling modulator 3
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of GPSM3 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr20:4,161,730...4,163,591
Ensembl chr20:4,161,730...4,189,072
|
|
| G
|
Gpt
|
glutamic--pyruvic transaminase
|
multiple interactions increases activity increases expression
|
EXP ISO
|
dapagliflozin inhibits the reaction [Arsenic Trioxide results in increased expression of GPT protein]; eriodictyol inhibits the reaction [Arsenic Trioxide results in increased expression of GPT protein]; naringenin inhibits the reaction [Arsenic Trioxide results in increased activity of GPT protein] Docosahexaenoic Acids inhibits the reaction [Arsenic Trioxide results in increased activity of GPT protein] 18alpha,20beta-hydroxy-11-oxo-norolean-12-en-3beta-yl-2-O-beta-D-glucopyranurosyl-alpha-D-glucopyranosiduronate magnesium tetrahydrate inhibits the reaction [Arsenic Trioxide results in increased activity of GPT protein]; baicalin inhibits the reaction [Arsenic Trioxide results in increased activity of GPT protein]
|
CTD |
PMID:23283742 PMID:28978146 PMID:29751151 PMID:33846815 PMID:35088608 PMID:38070468 More...
|
|
NCBI chr 7:110,295,599...110,300,134
Ensembl chr 7:110,296,206...110,300,160
|
|
| G
|
Gpt2
|
glutamic--pyruvic transaminase 2
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of GPT2 mRNA
|
CTD |
PMID:24356939 |
|
NCBI chr19:37,700,023...37,734,551
Ensembl chr19:37,691,901...37,733,917
|
|
| G
|
Gpx1
|
glutathione peroxidase 1
|
decreases activity increases expression decreases expression
|
EXP ISO
|
Arsenic Trioxide results in decreased activity of GPX1 protein Arsenic Trioxide results in increased expression of GPX1 mRNA Arsenic Trioxide results in decreased expression of GPX1 protein
|
CTD |
PMID:16867262 PMID:29986281 |
|
NCBI chr 8:117,905,462...117,906,588
Ensembl chr 8:117,905,280...117,906,581
|
|
| G
|
Gpx3
|
glutathione peroxidase 3
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of GPX3 mRNA
|
CTD |
PMID:15073043 |
|
NCBI chr10:39,529,335...39,537,406
Ensembl chr10:39,529,448...39,537,405
|
|
| G
|
Gpx4
|
glutathione peroxidase 4
|
increases expression multiple interactions decreases expression
|
ISO EXP
|
Arsenic Trioxide results in increased expression of GPX4 mRNA ferrostatin-1 inhibits the reaction [Arsenic Trioxide results in decreased expression of GPX4 mRNA]; ferrostatin-1 inhibits the reaction [Arsenic Trioxide results in decreased expression of GPX4 protein] Arsenic Trioxide results in decreased expression of GPX4 mRNA; Arsenic Trioxide results in decreased expression of GPX4 protein
|
CTD |
PMID:20458559 PMID:35195477 PMID:36509116 PMID:38266058 |
|
NCBI chr 7:10,300,833...10,303,629
Ensembl chr 7:10,300,832...10,303,629
|
|
| G
|
Gpx7
|
glutathione peroxidase 7
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of GPX7 mRNA
|
CTD |
PMID:25258189 |
|
NCBI chr 5:128,373,881...128,381,866
Ensembl chr 5:128,372,875...128,381,725
|
|
| G
|
Gramd2b
|
GRAM domain containing 2B
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of GRAMD2B mRNA
|
CTD |
PMID:15070760 |
|
NCBI chr18:52,082,128...52,180,056
Ensembl chr18:52,082,029...52,180,054
|
|
| G
|
Grb10
|
growth factor receptor bound protein 10
|
increases expression affects response to substance multiple interactions
|
ISO
|
Arsenic Trioxide results in increased expression of GRB10 mRNA GRB10 mRNA affects the susceptibility to Arsenic Trioxide [Arsenic Trioxide co-treated with apatinib] results in increased expression of GRB10 mRNA; [Arsenic Trioxide co-treated with apatinib] results in increased expression of GRB10 protein; GRB10 protein promotes the reaction [[Arsenic Trioxide co-treated with apatinib] results in decreased expression of BCL2 protein]; GRB10 protein promotes the reaction [[Arsenic Trioxide co-treated with apatinib] results in decreased expression of CTNNB1 protein]; GRB10 protein promotes the reaction [[Arsenic Trioxide co-treated with apatinib] results in decreased expression of MYC protein]; GRB10 protein promotes the reaction [[Arsenic Trioxide co-treated with apatinib] results in decreased phosphorylation of GSK3B protein]; GRB10 protein promotes the reaction [[Arsenic Trioxide co-treated with apatinib] results in decreased phosphorylation of MTOR protein]; GRB10 protein promotes the reaction [[Arsenic Trioxide co-treated with apatinib] results in increased cleavage of CASP3 protein]; GRB10 protein promotes the reaction [[Arsenic Trioxide co-treated with apatinib] results in increased cleavage of CASP9 protein]; GRB10 protein promotes the reaction [[Arsenic Trioxide co-treated with apatinib] results in increased cleavage of PARP1 protein]; GRB10 protein promotes the reaction [[Arsenic Trioxide co-treated with apatinib] results in increased expression of BAX protein]
|
CTD |
PMID:20458559 PMID:23911876 PMID:27829220 PMID:39223679 |
|
NCBI chr14:90,708,653...90,816,399
Ensembl chr14:90,708,653...90,816,387
|
|
| G
|
Grb2
|
growth factor receptor bound protein 2
|
decreases expression increases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of GRB2 protein Arsenic Trioxide results in increased expression of GRB2 mRNA
|
CTD |
PMID:20458559 PMID:25419056 |
|
NCBI chr10:101,380,354...101,448,138
Ensembl chr10:101,380,356...101,448,138
|
|
| G
|
Grb7
|
growth factor receptor bound protein 7
|
decreases response to substance
|
ISO
|
GRB7 protein results in decreased susceptibility to Arsenic Trioxide
|
CTD |
PMID:20707922 |
|
NCBI chr10:83,936,538...83,949,344
Ensembl chr10:83,939,299...83,949,382
|
|
| G
|
Greb1
|
growth regulating estrogen receptor binding 1
|
multiple interactions increases expression
|
ISO
|
afimoxifene inhibits the reaction [[Arsenic Trioxide results in increased expression of ESR1 protein] which results in increased expression of GREB1 mRNA]; afimoxifene inhibits the reaction [Arsenic Trioxide results in increased expression of GREB1 mRNA]; Fulvestrant inhibits the reaction [[Arsenic Trioxide results in increased expression of ESR1 protein] which results in increased expression of GREB1 mRNA]; Fulvestrant inhibits the reaction [Arsenic Trioxide results in increased expression of GREB1 mRNA]; S-Adenosylmethionine inhibits the reaction [[Arsenic Trioxide results in increased expression of ESR1 protein] which results in increased expression of GREB1 mRNA]; S-Adenosylmethionine inhibits the reaction [Arsenic Trioxide results in increased expression of GREB1 mRNA] [Arsenic Trioxide results in increased expression of ESR1 protein] which results in increased expression of GREB1 mRNA; Arsenic Trioxide results in increased expression of GREB1 mRNA
|
CTD |
PMID:22558281 |
|
NCBI chr 6:45,169,289...45,321,973
Ensembl chr 6:45,169,289...45,291,126
|
|
| G
|
Grem1
|
gremlin 1, DAN family BMP antagonist
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of GREM1 mRNA
|
CTD |
PMID:19128835 |
|
NCBI chr 3:120,966,639...120,978,319
Ensembl chr 3:120,966,623...120,979,089
|
|
| G
|
Grhpr
|
glyoxylate and hydroxypyruvate reductase
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of GRHPR mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr 5:64,029,856...64,039,287
Ensembl chr 5:64,022,368...64,039,276
|
|
| G
|
Gria1
|
glutamate ionotropic receptor AMPA type subunit 1
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of GRIA1 mRNA
|
CTD |
PMID:24831965 |
|
NCBI chr10:41,710,540...42,030,105
Ensembl chr10:41,711,080...42,030,309
|
|
| G
|
Gria2
|
glutamate ionotropic receptor AMPA type subunit 2
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of GRIA2 mRNA
|
CTD |
PMID:24831965 |
|
NCBI chr 2:168,247,490...168,367,616
Ensembl chr 2:168,247,496...168,367,616
|
|
| G
|
Grid2
|
glutamate ionotropic receptor delta type subunit 2
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of GRID2 mRNA
|
CTD |
PMID:24831965 |
|
NCBI chr 4:93,745,165...95,222,354
Ensembl chr 4:93,745,277...95,219,868
|
|
| G
|
Grik3
|
glutamate ionotropic receptor kainate type subunit 3
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of GRIK3 mRNA
|
CTD |
PMID:26705709 |
|
NCBI chr 5:143,052,442...143,268,873
Ensembl chr 5:143,052,442...143,268,873
|
|
| G
|
Grik4
|
glutamate ionotropic receptor kainate type subunit 4
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of GRIK4 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 8:51,802,045...52,228,751
Ensembl chr 8:51,802,058...52,102,063
|
|
| G
|
Grin1
|
glutamate ionotropic receptor NMDA type subunit 1
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of GRIN1 mRNA
|
CTD |
PMID:24831965 |
|
NCBI chr 3:28,501,836...28,528,754
Ensembl chr 3:28,501,836...28,528,754
|
|
| G
|
Grin2b
|
glutamate ionotropic receptor NMDA type subunit 2B
|
decreases expression multiple interactions
|
ISO
|
Arsenic Trioxide results in decreased expression of GRIN2B protein Resveratrol inhibits the reaction [Arsenic Trioxide results in decreased expression of GRIN2B protein]
|
CTD |
PMID:34050381 |
|
NCBI chr 4:170,297,811...170,775,420
Ensembl chr 4:170,322,617...170,773,570
|
|
| G
|
Grk4
|
G protein-coupled receptor kinase 4
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of GRK4 mRNA
|
CTD |
PMID:15761015 PMID:22535156 |
|
NCBI chr14:80,230,699...80,305,292
Ensembl chr14:80,230,816...80,305,292
|
|
| G
|
Grm1
|
glutamate metabotropic receptor 1
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of GRM1 mRNA
|
CTD |
PMID:24831965 |
|
NCBI chr 1:6,878,542...7,273,447
Ensembl chr 1:6,878,545...7,273,443
|
|
| G
|
Grn
|
granulin precursor
|
increases expression multiple interactions
|
ISO
|
Arsenic Trioxide results in increased expression of GRN mRNA [Arsenic Trioxide co-treated with Ascorbic Acid] results in increased expression of GRN mRNA
|
CTD |
PMID:25555879 |
|
NCBI chr10:87,887,834...87,893,938
Ensembl chr10:87,886,122...87,893,936
|
|
| G
|
Grp
|
gastrin releasing peptide
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of GRP mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr18:61,658,655...61,672,037
Ensembl chr18:61,658,250...61,672,037
|
|
| G
|
Gsc
|
goosecoid homeobox
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to GSC protein]
|
CTD |
PMID:26598702 |
|
NCBI chr 6:129,152,836...129,154,875
Ensembl chr 6:129,152,836...129,154,875
|
|
| G
|
Gsdma
|
gasdermin A
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of GSDMA mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr10:84,110,590...84,135,804
Ensembl chr10:84,123,314...84,135,804
|
|
| G
|
Gsdmc
|
gasdermin C
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to GSDMC protein]
|
CTD |
PMID:26598702 |
|
NCBI chr 7:97,482,713...97,509,985
Ensembl chr 7:97,483,257...97,499,587
|
|
| G
|
Gsdme
|
gasdermin E
|
multiple interactions increases cleavage
|
ISO
|
Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased cleavage of GSDME protein]; FLNC protein affects the reaction [Arsenic Trioxide results in increased cleavage of GSDME protein]
|
CTD |
PMID:36801614 |
|
NCBI chr 4:80,590,344...80,651,943
Ensembl chr 4:80,588,614...80,641,525
|
|
| G
|
Gsk3b
|
glycogen synthase kinase 3 beta
|
multiple interactions increases phosphorylation decreases phosphorylation increases expression affects response to substance
|
ISO
|
3-methyladenine inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of GSK3B protein]; [Arsenic Trioxide co-treated with apatinib] results in decreased phosphorylation of GSK3B protein; [Arsenic Trioxide results in increased phosphorylation of and results in increased activity of GSK3B protein] which results in increased phosphorylation of and results in increased ubiquitination of and results in increased degradation of CCND1 protein; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of GSK3B protein]; AKT1 protein inhibits the reaction [Arsenic Trioxide results in decreased phosphorylation of GSK3B protein]; Arsenic Trioxide inhibits the reaction [INS protein results in increased phosphorylation of GSK3B protein]; Arsenic Trioxide inhibits the reaction [Sorafenib results in increased phosphorylation of GSK3B protein]; Arsenic Trioxide results in increased phosphorylation of and results in increased activity of GSK3B protein; AS3MT mRNA promotes the reaction [Arsenic Trioxide inhibits the reaction [INS protein results in increased phosphorylation of GSK3B protein]]; Deoxyglucose inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of GSK3B protein]; GRB10 protein promotes the reaction [[Arsenic Trioxide co-treated with apatinib] results in decreased phosphorylation of GSK3B protein]; GSK3B protein modified form affects the reaction [Arsenic Trioxide results in increased expression of CDKN1A protein]; IGF2BP2 protein promotes the reaction [Arsenic Trioxide inhibits the reaction [INS protein results in increased phosphorylation of GSK3B protein]]; METTL14 protein promotes the reaction [Arsenic Trioxide inhibits the reaction [INS protein results in increased phosphorylation of GSK3B protein]]; N-(1,2,3,5,6,7-hexahydro-S-indacen-4-ylcarbamoyl)-4-(2-hydroxy-2-propanyl)-2-furansulfonamide inhibits the reaction [Arsenic Trioxide inhibits the reaction [INS protein results in increased phosphorylation of GSK3B protein]]; N-(4-methoxybenzyl)-N'-(5-nitro-1,3-thiazol-2-yl)urea inhibits the reaction [Arsenic Trioxide results in decreased phosphorylation of GSK3B protein]; Palmitic Acid inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of GSK3B protein]; Rosiglitazone inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of GSK3B protein]; Sorafenib inhibits the reaction [Arsenic Trioxide results in decreased phosphorylation of GSK3B protein]; Taurine inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of GSK3B protein]; U 0126 inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of GSK3B protein] Arsenic Trioxide inhibits the reaction [INS protein results in increased phosphorylation of GSK3B protein]; Taurine inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of GSK3B protein] Arsenic Trioxide results in increased expression of GSK3B mRNA GSK3B protein affects the susceptibility to Arsenic Trioxide
|
CTD |
PMID:21278055 PMID:22521957 PMID:23949314 PMID:25246272 PMID:25416439 PMID:26966376 PMID:30362509 PMID:32305283 PMID:35226250 PMID:39223679 More...
|
|
NCBI chr11:76,004,502...76,154,665
Ensembl chr11:76,009,507...76,153,249
|
|
| G
|
Gsn
|
gelsolin
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to GSN protein]
|
CTD |
PMID:26598702 |
|
NCBI chr 3:38,982,605...39,035,849
Ensembl chr 3:38,982,671...39,035,850
|
|
| G
|
Gspt1
|
G1 to S phase transition 1
|
increases expression multiple interactions
|
ISO
|
Arsenic Trioxide results in increased expression of GSPT1 mRNA Metformin inhibits the reaction [Arsenic Trioxide results in increased expression of GSPT1 mRNA]
|
CTD |
PMID:22521957 PMID:29095437 |
|
NCBI chr10:4,867,687...4,904,186
Ensembl chr10:4,869,465...4,908,040
|
|
| G
|
Gspt2
|
G1 to S phase transition 2
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of GSPT2 mRNA
|
CTD |
PMID:25258189 |
|
NCBI chr X:63,582,649...63,597,467
Ensembl chr X:63,582,690...63,700,401
|
|
| G
|
Gsr
|
glutathione-disulfide reductase
|
multiple interactions decreases response to substance increases expression decreases activity
|
ISO EXP
|
Ascorbic Acid inhibits the reaction [Arsenic Trioxide results in decreased activity of GSR protein]; beta Carotene inhibits the reaction [Arsenic Trioxide results in decreased activity of GSR protein] Acetylcysteine inhibits the reaction [Arsenic Trioxide inhibits the reaction [GSR protein results in increased oxidation of NADP]]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in decreased activity of GSR protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased expression of GSR mRNA]; Arsenic Trioxide inhibits the reaction [GSR protein results in increased oxidation of NADP]; Arsenic Trioxide inhibits the reaction [GSR protein results in increased reduction of Glutathione Disulfide]; Arsenic Trioxide promotes the reaction [GSR protein binds to Glutathione Disulfide]; Arsenic Trioxide results in increased expression of and results in decreased activity of GSR protein; Buthionine Sulfoximine promotes the reaction [Arsenic Trioxide results in increased expression of GSR mRNA]; GSR protein inhibits the reaction [Arsenic Trioxide results in increased cleavage of CASP3 protein] GSR protein results in decreased susceptibility to Arsenic Trioxide [Arsenic Trioxide results in increased abundance of Arsenic] which results in increased expression of GSR mRNA; [Arsenic Trioxide results in increased abundance of Arsenic] which results in increased expression of GSR protein; [ruxolitinib co-treated with Arsenic Trioxide] results in decreased expression of GSR mRNA
|
CTD |
PMID:17258074 PMID:18715643 PMID:19417148 PMID:20707922 PMID:24634002 PMID:25542264 PMID:30012499 PMID:33434570 More...
|
|
NCBI chr16:65,185,574...65,228,742
Ensembl chr16:65,185,574...65,228,394
|
|
| G
|
Gsta1
|
glutathione S-transferase alpha 1
|
multiple interactions increases expression
|
ISO
|
Atrazine promotes the reaction [Arsenic Trioxide results in increased expression of GSTA1 mRNA]
|
CTD |
PMID:11678611 PMID:20458559 |
|
NCBI chr 9:31,199,887...31,216,606
Ensembl chr 9:31,199,888...31,211,528
|
|
| G
|
Gstm1
|
glutathione S-transferase mu 1
|
decreases response to substance increases expression
|
ISO
|
GSTM1 protein results in decreased susceptibility to Arsenic Trioxide Arsenic Trioxide results in increased expression of GSTM1 mRNA
|
CTD |
PMID:20067466 PMID:20458559 PMID:22521957 |
|
NCBI chr 2:198,338,005...198,346,007
Ensembl chr 2:198,338,008...198,343,569
|
|
| G
|
Gstm4
|
glutathione S-transferase mu 4
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of GSTM4 mRNA
|
CTD |
PMID:22521957 |
|
NCBI chr 2:198,356,114...198,373,487
Ensembl chr 2:198,358,744...198,373,638
|
|
| G
|
Gstm5
|
glutathione S-transferase, mu 5
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of GSTM3 mRNA
|
CTD |
PMID:22521957 |
|
NCBI chr 2:198,219,769...198,222,732
Ensembl chr 2:198,219,647...198,222,731
|
|
| G
|
Gstm5l
|
glutathione S-transferase, mu 5-like
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to GSTM5 protein]
|
CTD |
PMID:26598702 |
|
NCBI chr 2:198,231,285...198,238,122
Ensembl chr 2:198,232,596...198,238,252
|
|
| G
|
Gsto1
|
glutathione S-transferase omega 1
|
multiple interactions increases expression
|
ISO
|
[Arsenic Trioxide results in increased abundance of Arsenic] which results in increased expression of GSTO1 mRNA Arsenic Trioxide results in increased expression of GSTO1 mRNA
|
CTD |
PMID:33434570 PMID:35676786 |
|
NCBI chr 1:256,662,377...256,672,515
Ensembl chr 1:256,662,531...256,676,167
|
|
| G
|
Gsto2
|
glutathione S-transferase omega 2
|
multiple interactions
|
ISO
|
[Arsenic Trioxide results in increased abundance of Arsenic] which results in increased expression of GSTO2 mRNA
|
CTD |
PMID:33434570 |
|
NCBI chr 1:256,673,376...256,695,154
Ensembl chr 1:256,673,274...256,695,146
|
|
| G
|
Gstp1
|
glutathione S-transferase pi 1
|
decreases response to substance multiple interactions decreases methylation increases expression
|
ISO
|
GSTP1 protein results in decreased susceptibility to Arsenic Trioxide [Arsenic Trioxide results in decreased methylation of GSTP1 promoter] which results in increased expression of GSTP1 mRNA; Arsenic Trioxide promotes the reaction [Decitabine results in increased expression of GSTP1 mRNA]; Arsenic Trioxide results in increased expression of and affects the localization of GSTP1 protein; Decitabine promotes the reaction [Arsenic Trioxide results in increased expression of GSTP1 mRNA]; GSTP1 mutant form promotes the reaction [[Arsenic Trioxide co-treated with Ethacrynic Acid] results in increased cleavage of CASP3 protein]; GSTP1 mutant form promotes the reaction [[Arsenic Trioxide co-treated with Ethacrynic Acid] results in increased cleavage of CASP9 protein]; GSTP1 mutant form promotes the reaction [[Arsenic Trioxide co-treated with Ethacrynic Acid] results in increased cleavage of PARP1 protein]; GSTP1 protein results in decreased susceptibility to [Arsenic Trioxide co-treated with Ethacrynic Acid]
|
CTD |
PMID:15231573 PMID:16613325 PMID:23082001 |
|
NCBI chr 1:210,767,237...210,770,242
Ensembl chr 1:210,767,237...210,769,705
|
|
| G
|
Gstt1
|
glutathione S-transferase theta 1
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of GSTT1 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr20:12,856,068...12,873,020
Ensembl chr20:12,856,083...12,873,019
|
|
| G
|
Gstz1
|
glutathione S-transferase zeta 1
|
multiple interactions increases expression
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to GSTZ1 protein] Arsenic Trioxide results in increased expression of GSTZ1 mRNA
|
CTD |
PMID:15761015 PMID:26598702 |
|
NCBI chr 6:112,525,576...112,536,228
Ensembl chr 6:112,525,377...112,536,233
|
|
| G
|
Gtf2a1
|
general transcription factor 2A subunit 1
|
increases sumoylation
|
ISO
|
Arsenic Trioxide results in increased sumoylation of GTF2A1 protein
|
CTD |
PMID:28318385 |
|
NCBI chr 6:116,219,614...116,252,220
Ensembl chr 6:116,219,614...116,252,220
|
|
| G
|
Gtf2h2
|
general transcription factor IIH subunit 2
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of GTF2H2 mRNA
|
CTD |
PMID:35676786 |
|
NCBI chr 2:33,358,863...33,386,726
Ensembl chr 2:33,358,869...33,386,688
|
|
| G
|
Gtf2i
|
general transcription factor II I
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of GTF2I mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr12:28,037,344...28,112,677
Ensembl chr12:28,037,853...28,112,677
|
|
| G
|
Gucy1a2
|
guanylate cyclase 1 soluble subunit alpha 2
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of GUCY1A2 mRNA alternative form
|
CTD |
PMID:35676786 |
|
NCBI chr 8:8,785,212...9,174,322
Ensembl chr 8:8,785,121...9,174,272
|
|
| G
|
Guk1
|
guanylate kinase 1
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of GUK1 mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr10:44,471,075...44,488,332
Ensembl chr10:44,471,085...44,479,355
|
|
| G
|
Gulp1
|
GULP PTB domain containing engulfment adaptor 1
|
decreases response to substance
|
ISO
|
GULP1 protein results in decreased susceptibility to Arsenic Trioxide
|
CTD |
PMID:20707922 |
|
NCBI chr 9:54,114,823...54,391,058
Ensembl chr 9:54,114,731...54,397,452
|
|
| G
|
Gypa
|
glycophorin A
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of GYPA protein
|
CTD |
PMID:16360329 |
|
NCBI chr19:44,354,669...44,370,304
Ensembl chr19:44,354,706...44,370,291
|
|
| G
|
Gys1
|
glycogen synthase 1
|
decreases phosphorylation multiple interactions
|
ISO
|
Arsenic Trioxide results in decreased phosphorylation of GYS1 protein Taurine inhibits the reaction [Arsenic Trioxide results in decreased phosphorylation of GYS1 protein] 3-methyladenine inhibits the reaction [Arsenic Trioxide results in decreased phosphorylation of GYS1 protein]; Palmitic Acid inhibits the reaction [Arsenic Trioxide results in decreased phosphorylation of GYS1 protein]; Rosiglitazone inhibits the reaction [Arsenic Trioxide results in decreased phosphorylation of GYS1 protein]; Taurine inhibits the reaction [Arsenic Trioxide results in decreased phosphorylation of GYS1 protein]
|
CTD |
PMID:30362509 |
|
NCBI chr 1:105,051,916...105,071,763
Ensembl chr 1:105,051,961...105,072,419
|
|
| G
|
H1f0
|
H1.0 linker histone
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of H1-0 mRNA
|
CTD |
PMID:22521957 |
|
NCBI chr 7:112,473,280...112,475,140
Ensembl chr 7:112,473,222...112,475,006
|
|
| G
|
H1f2
|
H1.2 linker histone, cluster member
|
multiple interactions
|
ISO
|
[Tretinoin co-treated with Arsenic Trioxide] results in decreased expression of H1-2 mRNA
|
CTD |
PMID:15894607 |
|
NCBI chr17:41,818,962...41,820,453
Ensembl chr17:41,779,051...41,822,317
|
|
| G
|
H2ac20
|
H2A clustered histone 20
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of H2AC20 mRNA
|
CTD |
PMID:25258189 |
|
NCBI chr 2:186,468,748...186,469,226
|
|
| G
|
H2ac4
|
H2A clustered histone 4
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of HIST1H2AC mRNA
|
CTD |
PMID:26705709 |
|
NCBI chr17:47,495,624...47,496,127
Ensembl chr17:47,495,546...47,496,173
|
|
| G
|
H2ax
|
H2A.X variant histone
|
multiple interactions increases expression increases phosphorylation
|
ISO EXP
|
[Arsenic Trioxide co-treated with ruxolitinib] results in increased phosphorylation of H2AX protein; [Arsenic Trioxide co-treated with Sulindac] results in increased phosphorylation of H2AX protein; Arsenic Trioxide inhibits the reaction [SHH protein inhibits the reaction [Cisplatin results in increased phosphorylation of H2AX protein]]; MUS81 protein mutant form inhibits the reaction [Arsenic Trioxide results in increased expression of H2AX protein modified form] 2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [Arsenic Trioxide results in increased expression of H2AX protein] Arsenic Trioxide results in increased expression of H2AX protein; Arsenic Trioxide results in increased expression of H2AX protein modified form Arsenic Trioxide results in increased phosphorylation of H2AX protein
|
CTD |
PMID:16891316 PMID:18636201 PMID:23337567 PMID:23861973 PMID:28265077 PMID:28318385 PMID:30012499 PMID:31597699 More...
|
|
NCBI chr 8:53,568,718...53,570,072
Ensembl chr 8:53,568,281...53,573,079
|
|
| G
|
H2bc14
|
H2B clustered histone 14
|
multiple interactions decreases expression
|
ISO
|
[Arsenic Trioxide co-treated with Ascorbic Acid] results in decreased expression of H2BC5 mRNA Arsenic Trioxide results in decreased expression of H2BC5 mRNA
|
CTD |
PMID:25555879 |
|
NCBI chr17:47,488,627...47,489,008
|
|
| G
|
H2bc9
|
H2B clustered histone 9
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of H2BC9 mRNA
|
CTD |
PMID:26705709 |
|
NCBI chr17:47,166,372...47,174,369
|
|
| G
|
H3f3b
|
H3.3 histone B
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of H3-3B mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr10:101,755,404...101,764,616
Ensembl chr10:101,755,404...101,757,636
|
|
| G
|
H3f4
|
H3.4 histone, cluster member
|
multiple interactions increases acetylation
|
ISO
|
Arsenic Trioxide results in increased phosphorylation of and results in increased acetylation of H3-4 protein Arsenic Trioxide results in increased acetylation of H3F4 protein
|
CTD |
PMID:12388546 PMID:19679824 |
|
NCBI chr10:44,240,282...44,240,842
|
|
| G
|
H4c3
|
H4 clustered histone 3
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of H4C6 mRNA
|
CTD |
PMID:22521957 |
|
NCBI chr17:41,796,600...41,860,389
|
|
| G
|
H6pd
|
hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of H6PD mRNA
|
CTD |
PMID:27829220 |
|
NCBI chr 5:165,717,456...165,753,158
Ensembl chr 5:165,721,654...165,753,125
|
|
| G
|
Hacd4
|
3-hydroxyacyl-CoA dehydratase 4
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of HACD4 mRNA
|
CTD |
PMID:26705709 |
|
NCBI chr 5:107,935,514...107,961,271
Ensembl chr 5:107,934,937...107,962,836
|
|
| G
|
Hacl1
|
2-hydroxyacyl-CoA lyase 1
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to HACL1 protein]
|
CTD |
PMID:26598702 |
|
NCBI chr16:6,831,293...6,869,410
Ensembl chr16:6,833,268...6,869,410
|
|
| G
|
Hadh
|
hydroxyacyl-CoA dehydrogenase
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of HADH mRNA
|
CTD |
PMID:30237538 |
|
NCBI chr 2:222,462,049...222,504,446
Ensembl chr 2:222,462,049...222,504,446
|
|
| G
|
Hagh
|
hydroxyacyl glutathione hydrolase
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to HAGH protein]
|
CTD |
PMID:26598702 |
|
NCBI chr10:14,379,400...14,394,046
Ensembl chr10:14,382,410...14,394,043
|
|
| G
|
Hal
|
histidine ammonia lyase
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of HAL mRNA
|
CTD |
PMID:34108876 |
|
NCBI chr 7:29,894,495...29,924,744
Ensembl chr 7:29,893,855...29,924,744
|
|
| G
|
Hapln1
|
hyaluronan and proteoglycan link protein 1
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of HAPLN1 mRNA
|
CTD |
PMID:35676786 |
|
NCBI chr 2:22,366,967...22,431,709
Ensembl chr 2:22,366,967...22,429,098
|
|
| G
|
Hars1
|
histidyl-tRNA synthetase 1
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to HARS1 protein]
|
CTD |
PMID:26598702 |
|
NCBI chr18:28,655,669...28,672,712
Ensembl chr18:28,655,671...28,672,712
|
|
| G
|
Hars2
|
histidyl-tRNA synthetase 2, mitochondrial
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to HARS2 protein]
|
CTD |
PMID:26598702 |
|
NCBI chr18:28,672,810...28,682,367
Ensembl chr18:28,672,824...28,682,359
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| G
|
Has2
|
hyaluronan synthase 2
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of HAS2 mRNA
|
CTD |
PMID:25258189 PMID:26705709 |
|
NCBI chr 7:90,002,929...90,028,933
Ensembl chr 7:90,002,929...90,018,535
|
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| G
|
Has3
|
hyaluronan synthase 3
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of HAS3 mRNA
|
CTD |
PMID:26705709 |
|
NCBI chr19:51,668,276...51,691,042
|
|
| G
|
Hat1
|
histone acetyltransferase 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of HAT1 protein
|
CTD |
PMID:25419056 |
|
NCBI chr 3:76,624,442...76,672,701
Ensembl chr 3:76,624,869...76,672,696
|
|
| G
|
Haus6
|
HAUS augmin like complex subunit 6
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of HAUS6 mRNA
|
CTD |
PMID:25258189 |
|
NCBI chr 5:106,162,526...106,201,503
Ensembl chr 5:106,162,526...106,199,072
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| G
|
Havcr1
|
hepatitis A virus cellular receptor 1
|
multiple interactions increases expression
|
EXP
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Febuxostat inhibits the reaction [Arsenic Trioxide results in increased expression of HAVCR1 protein]
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CTD |
PMID:37689273 |
|
NCBI chr10:31,619,914...31,652,955
Ensembl chr10:31,619,897...31,653,268
|
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| G
|
Havcr2
|
hepatitis A virus cellular receptor 2
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of HAVCR2 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr10:31,383,801...31,415,334
Ensembl chr10:31,383,925...31,413,872
|
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| G
|
Hbb
|
hemoglobin subunit beta
|
affects expression
|
ISO
|
Arsenic Trioxide affects the expression of HBB mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 1:167,662,310...167,663,721
Ensembl chr 1:167,630,245...167,663,873
|
|
| G
|
Hbegf
|
heparin-binding EGF-like growth factor
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of HBEGF mRNA
|
CTD |
PMID:25258189 PMID:26705709 |
|
NCBI chr18:28,380,337...28,390,220
Ensembl chr18:28,380,337...28,390,220
|
|
| G
|
Hbp1
|
HMG-box transcription factor 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of HBP1 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 6:54,257,118...54,283,373
Ensembl chr 6:54,256,864...54,283,366
|
|
| G
|
Hcfc1
|
host cell factor C1
|
multiple interactions increases expression
|
ISO
|
[Arsenic Trioxide co-treated with Ascorbic Acid] results in increased expression of HCFC1 mRNA Arsenic Trioxide results in increased expression of HCFC1 mRNA
|
CTD |
PMID:25555879 |
|
NCBI chr X:156,839,100...156,864,132
Ensembl chr X:156,839,100...156,863,813
|
|
| G
|
Hcls1
|
hematopoietic cell specific Lyn substrate 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of HCLS1 mRNA
|
CTD |
PMID:26705709 |
|
NCBI chr11:77,322,873...77,346,333
Ensembl chr11:77,322,873...77,346,387
|
|
| G
|
Hcrtr1
|
hypocretin receptor 1
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of HCRTR1 mRNA
|
CTD |
PMID:15761015 |
|
NCBI chr 5:147,761,392...147,771,846
Ensembl chr 5:147,760,145...147,770,850
|
|
| G
|
Hcst
|
hematopoietic cell signal transducer
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of HCST mRNA
|
CTD |
PMID:19128835 |
|
NCBI chr 1:94,804,429...94,806,661
Ensembl chr 1:94,804,430...94,806,641
|
|
| G
|
Hdac1
|
histone deacetylase 1
|
multiple interactions
|
ISO
|
[[Arsenic Trioxide results in increased phosphorylation of JUN protein] which binds to HDAC1 protein] which binds to CDKN1A promoter; [Arsenic Trioxide results in increased phosphorylation of JUN protein] which binds to HDAC1 protein; [Valproic Acid co-treated with Arsenic Trioxide] results in decreased expression of HDAC1 mRNA; Arsenic Trioxide promotes the reaction [[TGIF1 protein co-treated with HDAC1 protein] binds to CDKN1A promoter]; Arsenic Trioxide promotes the reaction [[TGIF1 protein co-treated with HDAC1 protein] results in decreased expression of CDKN1A mRNA]
|
CTD |
PMID:18210215 PMID:20074581 PMID:25815518 |
|
NCBI chr 5:147,138,328...147,165,387
Ensembl chr 5:147,138,156...147,165,387
|
|
| G
|
Hdac10
|
histone deacetylase 10
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of HDAC10 mRNA
|
CTD |
PMID:35676786 |
|
NCBI chr 7:122,078,768...122,084,457
Ensembl chr 7:122,078,768...122,083,870
|
|
| G
|
Hdac2
|
histone deacetylase 2
|
affects expression increases methylation
|
ISO
|
Arsenic Trioxide affects the expression of HDAC2 mRNA Arsenic Trioxide results in increased methylation of HDAC2 promoter
|
CTD |
PMID:25574600 PMID:26046465 |
|
NCBI chr20:42,101,815...42,126,486
Ensembl chr20:42,102,861...42,126,311
|
|
| G
|
Hdac4
|
histone deacetylase 4
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of HDAC4 mRNA
|
CTD |
PMID:22521957 |
|
NCBI chr 9:99,950,972...100,200,994
Ensembl chr 9:99,955,116...100,197,637
|
|
| G
|
Hdac8
|
histone deacetylase 8
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of HDAC8 mRNA
|
CTD |
PMID:22521957 |
|
NCBI chr X:71,425,240...71,632,865
Ensembl chr X:71,394,928...71,632,865
|
|
| G
|
Hdgf
|
heparin binding growth factor
|
affects expression
|
ISO
|
Arsenic Trioxide affects the expression of HDGF mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr 2:175,668,290...175,677,614
Ensembl chr 2:175,668,324...175,677,225
|
|
| G
|
Hdhd3
|
haloacid dehalogenase-like hydrolase domain containing 3
|
decreases response to substance
|
ISO
|
HDHD3 protein results in decreased susceptibility to Arsenic Trioxide
|
CTD |
PMID:20707922 |
|
NCBI chr 5:80,966,878...80,970,345
Ensembl chr 5:80,954,610...80,970,854
|
|
| G
|
Heatr5b
|
HEAT repeat containing 5B
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of HEATR5B mRNA
|
CTD |
PMID:27829220 |
|
NCBI chr 6:21,995,558...22,075,582
Ensembl chr 6:21,995,602...22,075,582
|
|
| G
|
Heatr6
|
HEAT repeat containing 6
|
decreases expression multiple interactions
|
ISO
|
Arsenic Trioxide results in decreased expression of HEATR6 mRNA Metformin inhibits the reaction [Arsenic Trioxide results in decreased expression of HEATR6 mRNA]
|
CTD |
PMID:29095437 |
|
NCBI chr10:69,132,532...69,161,334
Ensembl chr10:69,132,181...69,162,945
|
|
| G
|
Heca
|
hdc homolog, cell cycle regulator
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of HECA mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 1:14,345,306...14,395,226
Ensembl chr 1:14,345,306...14,395,191
|
|
| G
|
Henmt1
|
HEN methyltransferase 1
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to HENMT1 protein]
|
CTD |
PMID:26598702 |
|
NCBI chr 2:199,258,107...199,291,739
Ensembl chr 2:199,274,480...199,287,822
|
|
| G
|
Herc1
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of HERC1 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 8:75,796,347...75,965,347
Ensembl chr 8:75,796,357...75,965,347
|
|
| G
|
Hes1
|
hes family bHLH transcription factor 1
|
multiple interactions decreases expression
|
ISO
|
Arsenic Trioxide inhibits the reaction [PROM1 protein results in increased expression of HES1 mRNA] Arsenic Trioxide results in decreased expression of HES1 mRNA
|
CTD |
PMID:20458559 PMID:23497375 PMID:23832679 PMID:24685274 |
|
NCBI chr11:84,210,632...84,213,045
Ensembl chr11:84,210,633...84,213,061
|
|
| G
|
Hes5
|
hes family bHLH transcription factor 5
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of HES5 mRNA
|
CTD |
PMID:24685274 |
|
NCBI chr 5:170,804,511...170,807,988
Ensembl chr 5:170,803,940...170,806,021
|
|
| G
|
Hes7
|
hes family bHLH transcription factor 7
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of HES7 mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr10:54,322,971...54,327,776
Ensembl chr10:54,322,971...54,327,776
|
|
| G
|
Hey1
|
hes-related family bHLH transcription factor with YRPW motif 1
|
affects methylation decreases expression
|
ISO
|
Arsenic Trioxide affects the methylation of HEY1 promoter Arsenic Trioxide results in decreased expression of HEY1 mRNA
|
CTD |
PMID:24685274 PMID:26046465 |
|
NCBI chr 2:95,003,935...95,006,457
Ensembl chr 2:95,002,943...95,007,624
|
|
| G
|
Hey2
|
hes-related family bHLH transcription factor with YRPW motif 2
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of HEY2 mRNA
|
CTD |
PMID:26705709 |
|
NCBI chr 1:28,641,100...28,651,187
Ensembl chr 1:28,641,057...28,651,187
|
|
| G
|
Hfe
|
homeostatic iron regulator
|
decreases response to substance
|
ISO
|
HFE protein results in decreased susceptibility to Arsenic Trioxide
|
CTD |
PMID:20707922 |
|
NCBI chr17:41,841,302...41,849,359
Ensembl chr17:41,841,252...41,851,208
|
|
| G
|
Hgf
|
hepatocyte growth factor
|
increases expression decreases expression
|
ISO
|
Arsenic Trioxide results in increased expression of HGF mRNA Arsenic Trioxide results in decreased expression of HGF mRNA
|
CTD |
PMID:15761015 PMID:18414637 |
|
NCBI chr 4:19,628,902...19,700,467
Ensembl chr 4:19,632,267...19,700,851
|
|
| G
|
Hhipl2
|
HHIP like 2
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of HHIPL2 mRNA
|
CTD |
PMID:29633893 |
|
NCBI chr13:97,586,296...97,606,223
Ensembl chr13:97,586,341...97,606,223
|
|
| G
|
Hibadh
|
3-hydroxyisobutyrate dehydrogenase
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of HIBADH mRNA
|
CTD |
PMID:22521957 |
|
NCBI chr 4:82,979,759...83,077,819
Ensembl chr 4:82,979,765...83,111,242
|
|
| G
|
Hif1a
|
hypoxia inducible factor 1 subunit alpha
|
decreases expression affects expression increases expression multiple interactions
|
ISO
|
Arsenic Trioxide results in decreased expression of HIF1A; Arsenic Trioxide results in decreased expression of HIF1A mRNA; Arsenic Trioxide results in decreased expression of HIF1A protein Arsenic Trioxide affects the expression of HIF1A mRNA Arsenic Trioxide results in increased expression of HIF1A protein [Oxygen deficiency co-treated with Arsenic Trioxide] results in increased expression of HIF1A protein; Arsenic Trioxide promotes the reaction [cobaltous chloride results in increased expression of HIF1A protein]; Arsenic Trioxide promotes the reaction [Deferoxamine results in increased expression of HIF1A protein]
|
CTD |
PMID:12482858 PMID:15888669 PMID:16330433 PMID:19769630 PMID:19825857 PMID:20458559 PMID:25047463 PMID:25088040 PMID:29396848 PMID:34108876 More...
|
|
NCBI chr 6:98,357,788...98,405,068
Ensembl chr 6:98,359,910...98,405,323
|
|
| G
|
Higd1a
|
HIG1 hypoxia inducible domain family, member 1A
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of HIGD1A mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 8:130,391,658...130,400,888
Ensembl chr 8:130,391,661...130,400,888
|
|
| G
|
Hilpda
|
hypoxia inducible lipid droplet-associated
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of HILPDA mRNA
|
CTD |
PMID:15725085 |
|
NCBI chr 4:58,836,463...58,839,423
Ensembl chr 4:58,836,463...58,839,423
|
|
| G
|
Hinfp
|
histone H4 transcription factor
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of HINFP mRNA
|
CTD |
PMID:22521957 |
|
NCBI chr 8:53,525,576...53,541,101
Ensembl chr 8:53,527,236...53,540,555
|
|
| G
|
Hip1r
|
huntingtin interacting protein 1 related
|
decreases response to substance
|
ISO
|
HIP1R protein results in decreased susceptibility to Arsenic Trioxide
|
CTD |
PMID:20707922 |
|
NCBI chr12:38,251,085...38,279,756
Ensembl chr12:38,251,086...38,279,654
|
|
| G
|
Hipk1
|
homeodomain interacting protein kinase 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of HIPK1 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 2:193,937,261...193,988,247
Ensembl chr 2:193,937,261...193,975,164
|
|
| G
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Hira
|
histone cell cycle regulator
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of HIRA mRNA
|
CTD |
PMID:35676786 |
|
NCBI chr11:95,528,831...95,637,565
Ensembl chr11:95,528,831...95,638,549
|
|
| G
|
Hk1
|
hexokinase 1
|
multiple interactions increases expression decreases expression
|
ISO
|
[Ascorbic Acid co-treated with Arsenic Trioxide] results in decreased expression of HK1 protein; Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to HK1 protein]; Arsenic Trioxide promotes the reaction [Ascorbic Acid results in decreased expression of HK1 mRNA]; Arsenic Trioxide promotes the reaction [Ascorbic Acid results in decreased expression of HK1 protein]; Ascorbic Acid promotes the reaction [Arsenic Trioxide results in decreased expression of HK1 mRNA]; Ascorbic Acid promotes the reaction [Arsenic Trioxide results in decreased expression of HK1 protein] Arsenic Trioxide results in increased expression of HK1 mRNA Arsenic Trioxide results in decreased expression of HK1 mRNA; Arsenic Trioxide results in decreased expression of HK1 protein
|
CTD |
PMID:15761015 PMID:26598702 PMID:38160894 |
|
NCBI chr20:30,773,222...30,874,814
Ensembl chr20:30,773,220...30,874,814
|
|
| G
|
Hk2
|
hexokinase 2
|
decreases activity multiple interactions
|
ISO
|
Arsenic Trioxide results in decreased activity of HK2 protein Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to HK2 protein]
|
CTD |
PMID:26598702 |
|
NCBI chr 4:116,792,258...116,841,275
Ensembl chr 4:116,792,258...116,841,275
|
|
| G
|
Hk3
|
hexokinase 3
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of HK3 mRNA
|
CTD |
PMID:19128835 |
|
NCBI chr17:9,602,119...9,620,038
Ensembl chr17:9,605,016...9,620,037
|
|
| G
|
Hm13
|
histocompatibility minor 13
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of HM13 protein Arsenic Trioxide results in decreased expression of HM13 mRNA
|
CTD |
PMID:25419056 PMID:39716349 |
|
NCBI chr 3:161,606,059...161,641,382
Ensembl chr 3:161,606,052...161,644,805
|
|
| G
|
Hmbs
|
hydroxymethylbilane synthase
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of HMBS mRNA
|
CTD |
PMID:25258189 |
|
NCBI chr 8:53,570,364...53,577,758
Ensembl chr 8:53,570,364...53,577,802
|
|
| G
|
Hmcn2
|
hemicentin 2
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of HMCN2 mRNA
|
CTD |
PMID:35676786 |
|
NCBI chr 3:34,986,246...35,136,047
Ensembl chr 3:34,986,263...35,136,106
|
|
| G
|
Hmga1
|
high mobility group AT-hook 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of HMGA1 mRNA
|
CTD |
PMID:17547211 |
|
NCBI chr20:5,612,902...5,620,596
Ensembl chr20:5,613,471...5,620,593
|
|
| G
|
Hmgb1
|
high mobility group box 1
|
increases expression increases secretion decreases response to substance
|
ISO
|
Arsenic Trioxide results in increased expression of HMGB1 protein Arsenic Trioxide results in increased secretion of HMGB1 protein HMGB1 protein results in decreased susceptibility to Arsenic Trioxide
|
CTD |
PMID:25258189 PMID:27807322 PMID:37166470 PMID:38684648 |
|
NCBI chr12:11,009,236...11,015,941
Ensembl chr16:39,039,050...39,041,327 Ensembl chr12:39,039,050...39,041,327
|
|
| G
|
Hmgb2
|
high mobility group box 2
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of HMGB2 mRNA
|
CTD |
PMID:14703492 |
|
NCBI chr16:37,721,374...37,723,950
Ensembl chr16:37,721,379...37,723,860
|
|
| G
|
Hmgcs1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of HMGCS1 mRNA
|
CTD |
PMID:27829220 |
|
NCBI chr 2:53,379,457...53,399,807
Ensembl chr 2:53,382,643...53,399,802
|
|
| G
|
Hmgn2
|
high mobility group nucleosomal binding domain 2
|
increases expression increases response to substance
|
ISO
|
Arsenic Trioxide results in increased expression of HMGN2 mRNA HMGN2 protein results in increased susceptibility to Arsenic Trioxide
|
CTD |
PMID:17547211 PMID:20458559 PMID:20707922 |
|
NCBI chr 5:151,475,907...151,479,361
Ensembl chr 5:151,475,909...151,479,397
|
|
| G
|
Hmgxb3
|
HMG-box containing 3
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of HMGXB3 mRNA
|
CTD |
PMID:35676786 |
|
NCBI chr18:56,860,947...56,908,419
Ensembl chr18:56,860,947...56,908,419
|
|
| G
|
Hmox1
|
heme oxygenase 1
|
decreases response to substance multiple interactions increases expression decreases expression decreases activity
|
ISO EXP
|
HMOX1 protein results in decreased susceptibility to Arsenic Trioxide 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Arsenic Trioxide results in increased expression of HMOX1 protein]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Sulindac promotes the reaction [Arsenic Trioxide results in increased expression of HMOX1 protein]]; 6-Aminonicotinamide inhibits the reaction [Arsenic Trioxide results in increased expression of HMOX1 protein]; [Arsenic Trioxide co-treated with Bortezomib] results in decreased expression of HMOX1 mRNA; [Arsenic Trioxide results in increased abundance of Arsenic] which results in increased expression of HMOX1 mRNA; [Arsenic Trioxide results in increased abundance of Arsenic] which results in increased expression of HMOX1 protein; [zinc protoporphyrin results in decreased activity of HMOX1 protein] which results in increased susceptibility to Arsenic Trioxide; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased expression of HMOX1 protein]; Acetylcysteine promotes the reaction [Arsenic Trioxide results in increased expression of HMOX1 protein]; allicin inhibits the reaction [Arsenic Trioxide results in decreased expression of HMOX1 protein]; cobaltiprotoporphyrin promotes the reaction [Arsenic Trioxide results in increased expression of HMOX1 protein]; Dactinomycin inhibits the reaction [Arsenic Trioxide results in increased expression of HMOX1 mRNA]; Deoxyglucose inhibits the reaction [Arsenic Trioxide results in increased expression of HMOX1 protein]; Ethionamide inhibits the reaction [Arsenic Trioxide results in increased expression of HMOX1 mRNA]; HMOX1 protein inhibits the reaction [Arsenic Trioxide results in increased activity of CASP3 protein]; HMOX1 protein inhibits the reaction [Arsenic Trioxide results in increased expression of JUN protein modified form]; HMOX1 protein inhibits the reaction [Arsenic Trioxide results in increased expression of JUN protein]; HMOX1 protein inhibits the reaction [Arsenic Trioxide results in increased expression of MMP9 mRNA]; HMOX1 protein inhibits the reaction [Arsenic Trioxide results in increased expression of MMP9 protein]; JUN protein promotes the reaction [Arsenic Trioxide results in increased expression of HMOX1 protein]; MIR155 mRNA inhibits the reaction [Arsenic Trioxide results in decreased expression of HMOX1 protein]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [Arsenic Trioxide results in increased expression of HMOX1]; NFE2L2 protein affects the reaction [Arsenic Trioxide results in increased expression of HMOX1 mRNA]; NFE2L2 protein promotes the reaction [Arsenic Trioxide results in increased expression of HMOX1 protein]; PRKACA protein affects the reaction [Arsenic Trioxide results in increased expression of HMOX1 mRNA]; PRKACA protein affects the reaction [TRIM44 protein promotes the reaction [Arsenic Trioxide results in increased expression of HMOX1 mRNA]]; pyrazolanthrone inhibits the reaction [Sulindac promotes the reaction [Arsenic Trioxide results in increased expression of HMOX1 protein]]; RARA gene mutant form inhibits the reaction [Tretinoin inhibits the reaction [Arsenic Trioxide results in increased expression of HMOX1 protein]]; SB 203580 inhibits the reaction [Sulindac promotes the reaction [Arsenic Trioxide results in increased expression of HMOX1 protein]]; Sulindac promotes the reaction [Arsenic Trioxide results in increased expression of HMOX1 protein]; Tetrachlorodibenzodioxin promotes the reaction [Arsenic Trioxide results in increased expression of HMOX1 mRNA]; Tetrachlorodibenzodioxin promotes the reaction [Arsenic Trioxide results in increased expression of HMOX1 protein]; Thioctic Acid inhibits the reaction [Arsenic Trioxide results in increased expression of HMOX1 mRNA]; Thioctic Acid inhibits the reaction [Arsenic Trioxide results in increased expression of HMOX1 protein]; Tretinoin inhibits the reaction [Arsenic Trioxide results in increased expression of HMOX1 protein]; TRIM44 protein promotes the reaction [Arsenic Trioxide results in increased expression of HMOX1 mRNA]; zinc protoporphyrin promotes the reaction [Arsenic Trioxide results in increased expression of HMOX1 protein] Arsenic Trioxide results in increased expression of HMOX1; Arsenic Trioxide results in increased expression of HMOX1 mRNA; Arsenic Trioxide results in increased expression of HMOX1 protein 3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [Arsenic Trioxide results in increased expression of HMOX1 mRNA]; [Arsenic Trioxide co-treated with Grape Seed Proanthocyanidins] results in increased expression of HMOX1 mRNA; [Arsenic Trioxide co-treated with Tetrachlorodibenzodioxin] results in increased expression of HMOX1 protein; [Arsenic Trioxide results in increased abundance of Reactive Oxygen Species] which results in increased expression of HMOX1 protein; [Tetrachlorodibenzodioxin co-treated with Arsenic Trioxide] affects the expression of HMOX1 mRNA; Acetylcysteine inhibits the reaction [[Arsenic Trioxide results in increased abundance of Peroxides] which results in increased expression of HMOX1 protein]; Arsenic Trioxide promotes the reaction [Lutein results in increased expression of HMOX1 mRNA]; Arsenic Trioxide promotes the reaction [Lutein results in increased expression of HMOX1 protein]; CAT protein inhibits the reaction [Arsenic Trioxide results in increased expression of HMOX1 protein]; diphenyleneiodonium inhibits the reaction [Arsenic Trioxide results in increased expression of HMOX1 protein]; HMOX1 mRNA affects the reaction [Arsenic Trioxide results in increased expression of VEGFA mRNA]; Lutein promotes the reaction [Arsenic Trioxide results in increased expression of HMOX1 mRNA]; Lutein promotes the reaction [Arsenic Trioxide results in increased expression of HMOX1 protein]; NFE2L2 protein affects the reaction [Arsenic Trioxide results in increased expression of HMOX1 mRNA]; SB 203580 inhibits the reaction [Arsenic Trioxide results in increased expression of HMOX1 mRNA]; Thioctic Acid inhibits the reaction [Arsenic Trioxide results in increased expression of HMOX1 mRNA]; Thioctic Acid inhibits the reaction [Arsenic Trioxide results in increased expression of HMOX1 protein] Arsenic Trioxide results in decreased expression of HMOX1 mRNA; Arsenic Trioxide results in decreased expression of HMOX1 protein crocin inhibits the reaction [Arsenic Trioxide results in decreased expression of HMOX1 protein]; dapagliflozin inhibits the reaction [Arsenic Trioxide results in decreased activity of HMOX1 protein]; eriodictyol promotes the reaction [Arsenic Trioxide results in increased expression of HMOX1 mRNA]; eriodictyol promotes the reaction [Arsenic Trioxide results in increased expression of HMOX1 protein]; Nicorandil inhibits the reaction [Arsenic Trioxide results in decreased expression of HMOX1 protein]; oxymatrine promotes the reaction [Arsenic Trioxide results in increased expression of HMOX1 protein]; Resveratrol inhibits the reaction [Arsenic Trioxide results in decreased expression of HMOX1 mRNA]
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CTD |
PMID:15725085 PMID:15894607 PMID:16487037 PMID:17258074 PMID:17547211 PMID:18336854 PMID:18636201 PMID:19128835 PMID:19350554 PMID:19408305 PMID:19417148 PMID:20471514 PMID:20950636 PMID:21315065 PMID:21327864 PMID:21945491 PMID:22155346 PMID:22488045 PMID:23426167 PMID:23649692 PMID:24327821 PMID:24392034 PMID:24801890 PMID:24934751 PMID:25003661 PMID:25246272 PMID:25258189 PMID:25815309 PMID:25873331 PMID:25913414 PMID:25966753 PMID:26110921 PMID:26187899 PMID:26260164 PMID:26283888 PMID:26705709 PMID:26708503 PMID:27561292 PMID:27592447 PMID:27713174 PMID:27829220 PMID:28978146 PMID:29049341 PMID:29223816 PMID:29260515 PMID:29633893 PMID:29662624 PMID:30317545 PMID:31473893 PMID:32920515 PMID:33434570 PMID:35276128 PMID:35872050 PMID:36801614 PMID:38070468 PMID:38741475 PMID:39152142 PMID:39716349 More...
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NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,472,884...13,479,818
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Hmox2
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heme oxygenase 2
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increases expression
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ISO
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Arsenic Trioxide results in increased expression of HMOX2 mRNA
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CTD |
PMID:20458559 |
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NCBI chr10:11,303,512...11,337,640
Ensembl chr10:11,303,512...11,318,800
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| G
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Hnmt
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histamine N-methyltransferase
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multiple interactions
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ISO
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Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to HNMT protein]
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CTD |
PMID:26598702 |
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NCBI chr 3:26,978,274...27,010,291
Ensembl chr 3:26,977,933...27,010,482
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| G
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Hnrnpa1
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heterogeneous nuclear ribonucleoprotein A1
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increases expression
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ISO
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Arsenic Trioxide results in increased expression of HNRNPA1 mRNA
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CTD |
PMID:20458559 PMID:25258189 |
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NCBI chr 7:136,253,633...136,260,085
Ensembl chr 7:136,253,278...136,260,085
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| G
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Hnrnpa2b1
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heterogeneous nuclear ribonucleoprotein A2/B1
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decreases expression
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ISO
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Arsenic Trioxide results in decreased expression of HNRNPA2B1 protein
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CTD |
PMID:25419056 |
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NCBI chr 4:81,867,354...81,875,886
Ensembl chr 4:81,869,661...81,877,572
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Hnrnph1
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heterogeneous nuclear ribonucleoprotein H1
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increases expression
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ISO
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Arsenic Trioxide results in increased expression of HNRNPH1 mRNA; Arsenic Trioxide results in increased expression of HNRNPH1 protein
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CTD |
PMID:20458559 PMID:25258189 |
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NCBI chr10:35,187,412...35,203,909
Ensembl chr10:35,193,890...35,203,906
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| G
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Hnrnph2
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heterogeneous nuclear ribonucleoprotein H2
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increases expression
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ISO
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Arsenic Trioxide results in increased expression of HNRNPH2 mRNA
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CTD |
PMID:20458559 |
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NCBI chr X:102,074,175...102,080,115
Ensembl chr X:102,074,179...102,081,025
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| G
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Hnrnpk
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heterogeneous nuclear ribonucleoprotein K
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increases expression decreases expression
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ISO
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Arsenic Trioxide results in increased expression of HNRNPK protein Arsenic Trioxide results in decreased expression of HNRNPK protein
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CTD |
PMID:19364129 PMID:19747914 PMID:25419056 |
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NCBI chr17:6,269,302...6,280,429
Ensembl chr17:6,268,385...6,280,565
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Hnrnpl
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heterogeneous nuclear ribonucleoprotein L
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decreases expression
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ISO
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Arsenic Trioxide results in decreased expression of HNRNPL protein
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CTD |
PMID:25419056 |
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NCBI chr 1:93,226,373...93,239,084
Ensembl chr 1:93,235,729...93,239,061
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| G
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Hnrnpr
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heterogeneous nuclear ribonucleoprotein R
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increases expression decreases expression
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ISO
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Arsenic Trioxide results in increased expression of HNRNPR mRNA Arsenic Trioxide results in decreased expression of HNRNPR mRNA
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CTD |
PMID:20458559 PMID:39716349 |
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NCBI chr 5:153,826,482...153,872,272
Ensembl chr 5:153,826,692...153,858,344
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| G
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Homer2
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homer scaffold protein 2
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decreases expression
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ISO
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Arsenic Trioxide results in decreased expression of HOMER2 mRNA
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CTD |
PMID:29633893 |
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NCBI chr 1:144,968,207...145,069,022
Ensembl chr 1:144,976,436...145,068,997
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| G
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Homer3
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homer scaffold protein 3
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multiple interactions
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ISO
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HOMER3 protein affects the reaction [Arsenic Trioxide results in decreased expression of BCL2 protein]
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CTD |
PMID:23725168 |
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NCBI chr16:19,166,141...19,176,701
Ensembl chr16:19,165,482...19,176,640
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| G
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Hook2
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hook microtubule-tethering protein 2
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decreases expression multiple interactions
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ISO
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Arsenic Trioxide results in decreased expression of HOOK2 mRNA Metformin inhibits the reaction [Arsenic Trioxide results in decreased expression of HOOK2 mRNA]
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CTD |
PMID:29095437 |
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NCBI chr19:40,056,732...40,075,027
Ensembl chr19:40,056,732...40,081,270
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| G
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Hopx
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HOP homeobox
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decreases expression increases expression
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ISO
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Arsenic Trioxide results in decreased expression of HOPX mRNA Arsenic Trioxide results in increased expression of HOPX mRNA
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CTD |
PMID:22521957 PMID:26705709 PMID:39716349 |
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NCBI chr14:31,410,235...31,437,189
Ensembl chr14:31,410,221...31,437,188
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| G
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Hoxa2
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homeobox A2
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decreases expression
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ISO
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Arsenic Trioxide results in decreased expression of HOXA2 mRNA
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CTD |
PMID:26705709 |
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NCBI chr 4:82,593,389...82,597,589
Ensembl chr 4:82,593,389...82,595,692
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| G
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Hoxa3
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homeobox A3
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decreases expression
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ISO
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Arsenic Trioxide results in decreased expression of HOXA3 mRNA
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CTD |
PMID:26705709 |
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NCBI chr 4:82,599,860...82,643,831
Ensembl chr 4:82,599,860...82,643,831
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| G
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Hoxa5
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homeo box A5
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decreases expression
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ISO
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Arsenic Trioxide results in decreased expression of HOXA5 mRNA
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CTD |
PMID:21461292 |
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NCBI chr 4:82,632,958...82,636,851
Ensembl chr 4:82,632,306...82,639,038
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| G
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Hoxa9
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homeobox A9
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increases expression decreases expression
|
ISO
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Arsenic Trioxide results in increased expression of HOXA9 mRNA; Arsenic Trioxide results in increased expression of HOXA9 protein Arsenic Trioxide results in decreased expression of HOXA9 mRNA; Arsenic Trioxide results in decreased expression of HOXA9 protein
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CTD |
PMID:22541086 PMID:28961318 |
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NCBI chr 4:82,653,847...82,659,958
Ensembl chr 4:82,653,825...82,662,093
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| G
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Hoxb9
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homeo box B9
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increases expression
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ISO
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Arsenic Trioxide results in increased expression of HOXB9 mRNA
|
CTD |
PMID:27829220 |
|
NCBI chr10:81,733,857...81,737,363
Ensembl chr10:81,733,658...81,738,872
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| G
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Hoxc9
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homeobox C9
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increases expression
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ISO
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Arsenic Trioxide results in increased expression of HOXC9 protein
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CTD |
PMID:35467087 |
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NCBI chr 7:135,997,292...135,999,969
Ensembl chr 7:135,992,023...135,999,964
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| G
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Hoxd4
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homeo box D4
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increases expression
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ISO
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Arsenic Trioxide results in increased expression of HOXD4 mRNA
|
CTD |
PMID:15073043 |
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NCBI chr 3:80,021,886...80,041,462
Ensembl chr 3:80,036,900...80,038,948
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| G
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Hoxd8
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homeobox D8
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increases expression
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ISO
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Arsenic Trioxide results in increased expression of HOXD8 protein
|
CTD |
PMID:35467087 |
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NCBI chr 3:80,015,223...80,017,789
Ensembl chr 3:80,014,735...80,018,765
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| G
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Hpca
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hippocalcin
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decreases expression
|
ISO
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Arsenic Trioxide results in decreased expression of HPCA mRNA
|
CTD |
PMID:20458559 |
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NCBI chr 5:146,739,978...146,750,961
Ensembl chr 5:146,739,978...146,749,983
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| G
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Hpcal1
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hippocalcin-like 1
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multiple interactions increases expression
|
ISO
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[Tretinoin co-treated with Arsenic Trioxide] results in increased expression of HPCAL1 mRNA Arsenic Trioxide results in increased expression of HPCAL1 mRNA
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CTD |
PMID:15894607 PMID:20458559 |
|
NCBI chr 6:46,206,809...46,313,364
Ensembl chr 6:46,260,494...46,313,353
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| G
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Hpgd
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15-hydroxyprostaglandin dehydrogenase
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decreases expression increases expression
|
ISO
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Arsenic Trioxide results in decreased expression of HPGD mRNA Arsenic Trioxide results in increased expression of HPGD mRNA
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CTD |
PMID:19128835 PMID:20458559 |
|
NCBI chr16:38,996,876...39,034,831
Ensembl chr16:38,996,876...39,034,831
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| G
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Hpgds
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hematopoietic prostaglandin D synthase
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of HPGDS mRNA
|
CTD |
PMID:19128835 |
|
NCBI chr 4:95,698,265...95,727,733
Ensembl chr 4:95,702,392...95,938,501
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| G
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Hps3
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HPS3, biogenesis of lysosomal organelles complex 2 subunit 1
|
increases expression
|
ISO
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Arsenic Trioxide results in increased expression of HPS3 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 2:104,413,618...104,455,091
Ensembl chr 2:104,413,417...104,455,091
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| G
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Hps4
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HPS4, biogenesis of lysosomal organelles complex 3 subunit 2
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increases expression
|
ISO
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Arsenic Trioxide results in increased expression of HPS4 mRNA
|
CTD |
PMID:35676786 |
|
NCBI chr12:49,924,444...49,955,201
Ensembl chr12:49,924,444...49,953,613
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| G
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Hras
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HRas proto-oncogene, GTPase
|
increases expression multiple interactions
|
ISO
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Arsenic Trioxide results in increased expression of HRAS mRNA [Tetradecanoylphorbol Acetate co-treated with Arsenic Trioxide] results in increased expression of HRAS mRNA
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CTD |
PMID:18922899 PMID:29633893 |
|
NCBI chr 1:205,712,625...205,729,406
Ensembl chr 1:205,725,975...205,729,590
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| G
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Hrg
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histidine-rich glycoprotein
|
increases expression
|
ISO
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Arsenic Trioxide results in increased expression of HRG mRNA
|
CTD |
PMID:27829220 |
|
NCBI chr11:91,559,087...91,573,982
Ensembl chr11:91,559,091...91,573,982
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| G
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Hrk
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harakiri, BCL2 interacting protein
|
increases expression
|
EXP ISO
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Arsenic Trioxide results in increased expression of HRK mRNA
|
CTD |
PMID:19730151 PMID:20471514 PMID:24345465 |
|
NCBI chr12:44,048,402...44,070,561
Ensembl chr12:44,048,402...44,070,561
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| G
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Hs3st6
|
heparan sulfate-glucosamine 3-sulfotransferase 6
|
decreases expression
|
ISO
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Arsenic Trioxide results in decreased expression of HS3ST6 mRNA
|
CTD |
PMID:25258189 |
|
NCBI chr10:14,286,555...14,292,660
Ensembl chr10:14,286,507...14,292,660
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| G
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Hsd17b12
|
hydroxysteroid (17-beta) dehydrogenase 12
|
increases expression
|
ISO
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Arsenic Trioxide results in increased expression of HSD17B12 mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr 3:100,445,393...100,568,898
Ensembl chr 3:100,445,400...100,568,938
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| G
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Hsd17b2
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hydroxysteroid (17-beta) dehydrogenase 2
|
decreases expression
|
ISO
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Arsenic Trioxide results in decreased expression of HSD17B2 mRNA
|
CTD |
PMID:17547211 |
|
NCBI chr19:62,662,320...62,733,944
Ensembl chr19:62,662,098...62,733,943
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| G
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Hsd17b4
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hydroxysteroid (17-beta) dehydrogenase 4
|
increases expression
|
ISO
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Arsenic Trioxide results in increased expression of HSD17B4 protein
|
CTD |
PMID:25419056 |
|
NCBI chr18:45,515,427...45,604,467
Ensembl chr18:45,515,373...45,604,467
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| G
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Hsd17b6
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hydroxysteroid (17-beta) dehydrogenase 6
|
increases expression
|
ISO
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Arsenic Trioxide results in increased expression of HSD17B6 mRNA
|
CTD |
PMID:22521957 |
|
NCBI chr 7:831,407...850,950
Ensembl chr 7:831,421...850,873
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| G
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Hsd17b8
|
hydroxysteroid (17-beta) dehydrogenase 8
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of HSD17B8 mRNA
|
CTD |
PMID:27829220 |
|
NCBI chr20:4,828,571...4,830,635
Ensembl chr20:4,828,608...4,830,634
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| G
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Hsd3b2
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hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2
|
multiple interactions
|
ISO
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Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to HSD3B2 protein]
|
CTD |
PMID:26598702 |
|
NCBI chr 2:188,784,614...188,812,535
Ensembl chr 2:188,784,614...188,790,569
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| G
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Hsdl1
|
hydroxysteroid dehydrogenase like 1
|
multiple interactions
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ISO
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[Tretinoin co-treated with Arsenic Trioxide] results in decreased expression of HSDL1 mRNA
|
CTD |
PMID:15894607 |
|
NCBI chr19:64,524,435...64,540,527
Ensembl chr19:64,525,891...64,540,762
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| G
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Hsf1
|
heat shock transcription factor 1
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affects response to substance increases phosphorylation multiple interactions increases activity
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ISO
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HSF1 protein affects the susceptibility to Arsenic Trioxide Arsenic Trioxide results in increased phosphorylation of HSF1 protein 2-(morpholin-4-yl)benzo(h)chromen-4-one inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of HSF1 protein]; Arsenic Trioxide results in increased phosphorylation of and affects the localization of HSF1 protein; HSF1 protein affects the reaction [Arsenic Trioxide results in increased activity of CASP9 protein]; HSF1 protein affects the reaction [Arsenic Trioxide results in increased cleavage of PARP1 protein]; HSF1 protein affects the reaction [Arsenic Trioxide results in increased expression of HSPA1A protein]; HSPA1A protein promotes the reaction [Arsenic Trioxide results in increased phosphorylation of HSF1 protein]; MAP2K4 protein promotes the reaction [Arsenic Trioxide results in increased phosphorylation of HSF1 protein]; PI103 inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of HSF1 protein]; pyrazolanthrone inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of HSF1 protein] Arsenic Trioxide results in increased activity of HSF1 protein
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CTD |
PMID:15978632 PMID:20724260 PMID:22496356 PMID:34170685 |
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NCBI chr 7:110,076,710...110,103,665
Ensembl chr 7:110,076,710...110,103,665
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| G
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Hsf2
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heat shock transcription factor 2
|
increases expression
|
ISO
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Arsenic Trioxide results in increased expression of HSF2 mRNA
|
CTD |
PMID:25258189 |
|
NCBI chr20:37,366,301...37,393,922
Ensembl chr20:37,366,279...37,401,022
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| G
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Hsp90aa1
|
heat shock protein 90 alpha family class A member 1
|
increases expression multiple interactions affects response to substance
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ISO EXP
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Arsenic Trioxide results in increased expression of HSP90AA1 mRNA; Arsenic Trioxide results in increased expression of HSP90AA1 protein sulforaphane promotes the reaction [Arsenic Trioxide results in increased expression of HSP90AA1 protein] HSP90AA1 protein affects the susceptibility to Arsenic Trioxide
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CTD |
PMID:11940349 PMID:18081892 PMID:19364129 PMID:19371599 PMID:19417148 PMID:20458559 PMID:22922937 PMID:27592447 PMID:29633893 More...
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NCBI chr 6:135,523,604...135,529,687
Ensembl chr 6:135,523,616...135,528,499
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| G
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Hsp90ab1
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heat shock protein 90 alpha family class B member 1
|
increases expression affects response to substance decreases expression
|
ISO
|
Arsenic Trioxide results in increased expression of HSP90AB1 mRNA; Arsenic Trioxide results in increased expression of HSP90AB1 protein HSP90AB1 protein affects the susceptibility to Arsenic Trioxide Arsenic Trioxide results in decreased expression of HSP90AB1 protein
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CTD |
PMID:19364129 PMID:19371599 PMID:20458559 PMID:22521957 PMID:25419056 |
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NCBI chr 9:22,930,249...22,935,929
Ensembl chr 9:22,931,070...22,935,926
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| G
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Hsp90b1
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heat shock protein 90 beta family member 1
|
increases expression multiple interactions decreases expression
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EXP ISO
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Arsenic Trioxide results in increased expression of HSP90B1 protein Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased expression of HSP90B1 mRNA]; ATF4 protein promotes the reaction [Arsenic Trioxide results in increased expression of HSP90B1 protein]; Thapsigargin promotes the reaction [Arsenic Trioxide results in increased expression of HSP90B1 protein] Arsenic Trioxide results in increased expression of HSP90B1 mRNA; Arsenic Trioxide results in increased expression of HSP90B1 protein Arsenic Trioxide results in decreased expression of HSP90B1 mRNA Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased expression of HSP90B1 protein]
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CTD |
PMID:19364129 PMID:20458559 PMID:21145380 PMID:21533816 PMID:27638049 |
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NCBI chr 7:22,997,962...23,012,293
Ensembl chr 7:22,997,962...23,012,293
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| G
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Hspa1a
|
heat shock protein family A (Hsp70) member 1A
|
multiple interactions increases expression affects response to substance affects expression
|
ISO
|
2-(morpholin-4-yl)benzo(h)chromen-4-one inhibits the reaction [Arsenic Trioxide results in increased expression of HSPA1A protein]; HSF1 protein affects the reaction [Arsenic Trioxide results in increased expression of HSPA1A protein]; HSPA1A protein promotes the reaction [Arsenic Trioxide results in increased phosphorylation of HSF1 protein]; KNK 437 inhibits the reaction [Arsenic Trioxide results in increased expression of HSPA1A protein]; PI103 inhibits the reaction [Arsenic Trioxide results in increased expression of HSPA1A mRNA] Arsenic Trioxide results in increased expression of HSPA1A mRNA; Arsenic Trioxide results in increased expression of HSPA1A protein HSPA1A protein affects the susceptibility to Arsenic Trioxide Arsenic Trioxide affects the expression of HSPA1A mRNA
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CTD |
PMID:12749819 PMID:14610070 PMID:18081892 PMID:19364129 PMID:19371599 PMID:19417148 PMID:20458559 PMID:20724260 PMID:22496356 More...
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|
NCBI chr20:3,875,411...3,877,866
Ensembl chr20:3,855,780...3,877,979
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|
| G
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Hspa1b
|
heat shock protein family A (Hsp70) member 1B
|
increases expression affects response to substance affects expression
|
ISO
|
Arsenic Trioxide results in increased expression of HSPA1B mRNA HSPA1B protein affects the susceptibility to Arsenic Trioxide Arsenic Trioxide affects the expression of HSPA1B mRNA
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CTD |
PMID:17530438 PMID:19371599 PMID:19417148 PMID:23824090 PMID:24356939 PMID:25258189 PMID:27829220 More...
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|
NCBI chr20:3,859,756...3,863,800
Ensembl chr20:3,855,780...3,877,979
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|
| G
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Hspa1l
|
heat shock protein family A (Hsp70) member 1 like
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of HSPA1L mRNA
|
CTD |
PMID:27829220 |
|
NCBI chr20:3,853,496...3,860,223
Ensembl chr20:3,853,331...3,876,877
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|
| G
|
Hspa2
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heat shock protein family A (Hsp70) member 2
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of HSPA2 protein
|
CTD |
PMID:25419056 |
|
NCBI chr 6:100,864,172...100,866,946
Ensembl chr 6:100,864,553...100,867,133
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|
| G
|
Hspa4
|
heat shock protein family A (Hsp70) member 4
|
multiple interactions increases expression
|
ISO
|
Atrazine inhibits the reaction [Arsenic Trioxide results in increased expression of HSPA4 mRNA] Arsenic Trioxide results in increased expression of HSPA4 mRNA; Arsenic Trioxide results in increased expression of HSPA4 protein
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CTD |
PMID:11678611 PMID:14682389 PMID:15665116 PMID:19417148 PMID:20458559 |
|
NCBI chr10:37,908,866...37,951,994
Ensembl chr10:37,908,866...37,949,835
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|
| G
|
Hspa4l
|
heat shock protein family A (Hsp70) member 4 like
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of HSPA4L mRNA
|
CTD |
PMID:26705709 |
|
NCBI chr 2:125,668,346...125,726,404
Ensembl chr 2:125,668,236...125,720,986
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|
| G
|
Hspa5
|
heat shock protein family A (Hsp70) member 5
|
increases expression multiple interactions affects response to substance decreases expression
|
ISO EXP
|
Arsenic Trioxide results in increased expression of HSPA5 mRNA; Arsenic Trioxide results in increased expression of HSPA5 protein 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt inhibits the reaction [Arsenic Trioxide results in increased expression of HSPA5 protein]; 4-phenylbutyric acid inhibits the reaction [Arsenic Trioxide results in increased expression of HSPA5 protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased expression of HSPA5 mRNA]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased expression of HSPA5 protein]; antimony trichloride promotes the reaction [Arsenic Trioxide results in increased expression of HSPA5 mRNA]; Arsenic Trioxide promotes the reaction [antimony trichloride results in increased expression of HSPA5 mRNA]; ATF4 protein promotes the reaction [Arsenic Trioxide results in increased expression of HSPA5 protein]; HSPA5 mutant form inhibits the reaction [Arsenic Trioxide results in increased activity of CASP3 protein]; HSPA5 mutant form inhibits the reaction [Arsenic Trioxide results in increased activity of CASP7 protein]; HSPA5 mutant form inhibits the reaction [Arsenic Trioxide results in increased degradation of CASP12 protein]; Thapsigargin promotes the reaction [Arsenic Trioxide results in increased expression of HSPA5 protein]; Thioctic Acid inhibits the reaction [Arsenic Trioxide results in increased expression of HSPA5 protein] HSPA5 protein affects the susceptibility to Arsenic Trioxide [Arsenic Trioxide co-treated with Dactinomycin] results in decreased expression of HSPA5 mRNA; [Arsenic Trioxide co-treated with Dactinomycin] results in increased expression of HSPA5 protein; Acetylcysteine inhibits the reaction [Arsenic Trioxide promotes the reaction [Resveratrol results in increased expression of HSPA5 protein]]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased expression of HSPA5 protein]; Acetylcysteine inhibits the reaction [Resveratrol promotes the reaction [Arsenic Trioxide results in increased expression of HSPA5 protein]]; Arsenic Trioxide promotes the reaction [nilotinib results in increased expression of HSPA5 mRNA]; Arsenic Trioxide promotes the reaction [Resveratrol results in increased expression of HSPA5 protein]; Atrazine promotes the reaction [Arsenic Trioxide results in increased expression of HSPA5 mRNA]; Cycloheximide inhibits the reaction [Arsenic Trioxide results in increased expression of HSPA5 protein]; KIRA6 inhibits the reaction [Arsenic Trioxide results in increased expression of HSPA5 protein]; Resveratrol promotes the reaction [Arsenic Trioxide results in increased expression of HSPA5 protein]; SB 203580 inhibits the reaction [Arsenic Trioxide results in increased expression of HSPA5 protein]; selonsertib inhibits the reaction [Arsenic Trioxide results in increased expression of HSPA5 protein] Arsenic Trioxide results in decreased expression of HSPA5 mRNA
|
CTD |
PMID:11678611 PMID:19695276 PMID:21145380 PMID:21533816 PMID:22959511 PMID:23883479 PMID:23892647 PMID:24157283 PMID:24356939 PMID:25424538 PMID:26772155 PMID:27461142 PMID:27638049 PMID:34091186 PMID:34560123 More...
|
|
NCBI chr 3:38,453,016...38,457,475
Ensembl chr 3:38,453,041...38,458,790
|
|
| G
|
Hspa6l-ps1
|
heat shock protein family A (Hsp70) member 6 like, pseudogene 1
|
multiple interactions increases expression
|
ISO
|
MAP2K4 protein promotes the reaction [Arsenic Trioxide results in increased expression of HSPA6 mRNA]; MAP2K4 protein promotes the reaction [Arsenic Trioxide results in increased expression of HSPA6 protein]; pyrazolanthrone inhibits the reaction [Arsenic Trioxide results in increased expression of HSPA6 mRNA]; pyrazolanthrone inhibits the reaction [Arsenic Trioxide results in increased expression of HSPA6 protein] Arsenic Trioxide results in increased expression of HSPA6 mRNA; Arsenic Trioxide results in increased expression of HSPA6 protein
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CTD |
PMID:15978632 PMID:19364129 PMID:19417148 PMID:24356939 |
|
NCBI chr13:85,805,911...85,807,052
|
|
| G
|
Hspa8
|
heat shock protein family A (Hsp70) member 8
|
increases expression decreases expression
|
ISO
|
Arsenic Trioxide results in increased expression of HSPA8 protein Arsenic Trioxide results in increased expression of HSPA6 mRNA Arsenic Trioxide results in decreased expression of HSPA8 mRNA
|
CTD |
PMID:19364129 PMID:39716349 |
|
NCBI chr 8:50,080,514...50,084,376
Ensembl chr 8:50,080,199...50,084,372
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|
| G
|
Hspa9
|
heat shock protein family A (Hsp70) member 9
|
increases expression multiple interactions
|
ISO
|
Arsenic Trioxide results in increased expression of HSPA9 protein ATF4 protein promotes the reaction [Arsenic Trioxide results in increased expression of HSPA9 protein]
|
CTD |
PMID:27638049 |
|
NCBI chr18:26,810,004...26,832,958
Ensembl chr18:26,804,774...26,828,398
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|
| G
|
Hspb1
|
heat shock protein family B (small) member 1
|
decreases expression increases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of HSPB1 mRNA Arsenic Trioxide results in increased expression of HSPB1 mRNA; Arsenic Trioxide results in increased expression of HSPB1 protein
|
CTD |
PMID:15070760 PMID:15761015 PMID:18081892 PMID:19364129 PMID:19417148 PMID:25258189 More...
|
|
NCBI chr12:26,430,640...26,432,301
Ensembl chr12:26,430,640...26,432,301
|
|
| G
|
Hspb8
|
heat shock protein family B (small) member 8
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of HSPB8 mRNA
|
CTD |
PMID:26705709 |
|
NCBI chr12:45,835,899...45,866,449
Ensembl chr12:45,837,066...45,851,937
|
|
| G
|
Hspd1
|
heat shock protein family D (Hsp60) member 1
|
increases expression multiple interactions
|
ISO
|
Arsenic Trioxide results in increased expression of HSPD1 mRNA; Arsenic Trioxide results in increased expression of HSPD1 protein [Arsenic Trioxide co-treated with Curcumin] results in increased expression of HSPD1 protein
|
CTD |
PMID:19417148 PMID:20458559 PMID:22521957 PMID:27430728 |
|
NCBI chr 9:64,073,610...64,084,332
Ensembl chr 9:64,073,611...64,084,037
|
|
| G
|
Hsph1
|
heat shock protein family H (Hsp110) member 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of HSPH1 mRNA
|
CTD |
PMID:17530438 PMID:19417148 PMID:24356939 |
|
NCBI chr12:10,427,368...10,446,602
Ensembl chr12:10,427,297...10,446,891
|
|
| G
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Htatip2
|
HIV-1 Tat interactive protein 2
|
increases expression decreases response to substance
|
ISO
|
Arsenic Trioxide results in increased expression of HTATIP2 mRNA HTATIP2 protein results in decreased susceptibility to Arsenic Trioxide
|
CTD |
PMID:15761015 PMID:20707922 PMID:22521957 PMID:26705709 |
|
NCBI chr 1:108,609,424...108,624,810
Ensembl chr 1:108,605,811...108,624,815
|
|
| G
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Htatsf1
|
HIV-1 Tat specific factor 1
|
increases response to substance
|
ISO
|
HTATSF1 protein results in increased susceptibility to Arsenic Trioxide
|
CTD |
PMID:20707922 |
|
NCBI chr X:139,972,742...139,986,923
Ensembl chr X:139,972,742...139,986,923
|
|
| G
|
Htr1d
|
5-hydroxytryptamine receptor 1D
|
decreases response to substance
|
ISO
|
HTR1D protein results in decreased susceptibility to Arsenic Trioxide
|
CTD |
PMID:20707922 |
|
NCBI chr 5:153,939,735...153,960,012
Ensembl chr 5:153,939,516...153,960,012
|
|
| G
|
Htra2
|
HtrA serine peptidase 2
|
multiple interactions increases expression decreases localization
|
ISO
|
[Arsenic Trioxide co-treated with Quercetin] affects the localization of HTRA2 protein; [Arsenic Trioxide co-treated with TNF protein] affects the localization of HTRA2 protein; [lonidamine co-treated with Arsenic Trioxide] affects the localization of HTRA2 protein; Deoxyglucose promotes the reaction [Arsenic Trioxide results in decreased localization of HTRA2 protein] Arsenic Trioxide results in increased expression of HTRA2 mRNA
|
CTD |
PMID:17673311 PMID:18359480 PMID:21889928 PMID:22521957 PMID:23041229 |
|
NCBI chr 4:117,114,631...117,117,793
Ensembl chr 4:117,114,633...117,117,793
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|
| G
|
Htra3
|
HtrA serine peptidase 3
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of HTRA3 mRNA
|
CTD |
PMID:19128835 |
|
NCBI chr14:79,293,535...79,321,936
Ensembl chr14:79,293,541...79,321,936
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|
| G
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Hus1
|
HUS1 checkpoint clamp component
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of HUS1 mRNA
|
CTD |
PMID:22521957 |
|
NCBI chr14:87,902,458...87,917,221
Ensembl chr14:87,902,458...87,917,134
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|
| G
|
Huwe1
|
HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of HUWE1 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr X:24,350,708...24,480,798
Ensembl chr X:24,353,217...24,480,798
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|
| G
|
Hyal1
|
hyaluronidase 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of HYAL1 mRNA
|
CTD |
PMID:20458559 PMID:22521957 |
|
NCBI chr 8:117,129,311...117,133,162
Ensembl chr 8:117,129,277...117,133,146
|
|
| G
|
Hykk
|
hydroxylysine kinase
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to HYKK protein]
|
CTD |
PMID:26598702 |
|
NCBI chr 8:64,212,043...64,235,809
Ensembl chr 8:64,212,071...64,235,818
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|
| G
|
Iars1
|
isoleucyl-tRNA synthetase 1
|
increases expression decreases expression
|
ISO
|
Arsenic Trioxide results in increased expression of IARS1 mRNA Arsenic Trioxide results in decreased expression of IARS1 mRNA
|
CTD |
PMID:19128835 PMID:20458559 |
|
NCBI chr17:15,147,357...15,193,716
Ensembl chr17:15,147,357...15,193,652
|
|
| G
|
Icam1
|
intercellular adhesion molecule 1
|
multiple interactions increases expression decreases expression
|
ISO
|
[Arsenic Trioxide co-treated with Bortezomib] results in decreased expression of ICAM1 mRNA; [Tretinoin co-treated with Arsenic Trioxide] results in increased expression of ICAM1 mRNA; AG 1879 promotes the reaction [Arsenic Trioxide promotes the reaction [Tretinoin results in increased expression of ICAM1 protein]]; Arsenic Trioxide promotes the reaction [AG 1879 results in increased expression of ICAM1 protein]; Arsenic Trioxide promotes the reaction [Tretinoin results in increased expression of ICAM1 protein] Arsenic Trioxide results in increased expression of ICAM1; Arsenic Trioxide results in increased expression of ICAM1 mRNA; Arsenic Trioxide results in increased expression of ICAM1 protein Arsenic Trioxide results in decreased expression of ICAM1 mRNA
|
CTD |
PMID:12083632 PMID:15073043 PMID:15894607 PMID:18055984 PMID:20471514 PMID:23864846 PMID:24953245 PMID:25913414 PMID:27750169 More...
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|
NCBI chr 8:27,829,688...27,841,618
Ensembl chr 8:27,829,161...27,841,617
|
|
| G
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Icoslg
|
inducible T-cell co-stimulator ligand
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of ICOSLG mRNA
|
CTD |
PMID:22521957 |
|
NCBI chr20:10,600,078...10,610,385
Ensembl chr20:10,600,078...10,610,365
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|
| G
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Id1
|
inhibitor of DNA binding 1
|
increases expression decreases response to substance decreases expression multiple interactions
|
ISO
|
Arsenic Trioxide results in increased expression of ID1 mRNA ID1 protein results in decreased susceptibility to Arsenic Trioxide Arsenic Trioxide results in decreased expression of ID1 mRNA ID1 protein inhibits the reaction [Arsenic Trioxide results in decreased expression of BCL2 protein]; ID1 protein inhibits the reaction [Arsenic Trioxide results in increased expression of BAX protein]; ID1 protein inhibits the reaction [Arsenic Trioxide results in increased expression of CASP3 protein]
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CTD |
PMID:15761015 PMID:20707922 PMID:31079498 |
|
NCBI chr 3:161,671,525...161,672,691
Ensembl chr 3:161,671,538...161,672,685
|
|
| G
|
Id2
|
inhibitor of DNA binding 2
|
increases expression multiple interactions affects expression decreases expression
|
ISO
|
Arsenic Trioxide results in increased expression of ID2 mRNA [Tretinoin co-treated with Arsenic Trioxide] results in increased expression of ID2 mRNA Arsenic Trioxide affects the expression of ID2 mRNA; Arsenic Trioxide affects the expression of ID2 protein Arsenic Trioxide results in decreased expression of ID2 mRNA
|
CTD |
PMID:15761015 PMID:15894607 PMID:21921037 PMID:24356939 PMID:25076250 |
|
NCBI chr 6:47,469,162...47,470,995
Ensembl chr 6:47,457,554...47,472,961
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|
| G
|
Id3
|
inhibitor of DNA binding 3
|
multiple interactions
|
ISO
|
[Arsenic Trioxide co-treated with apatinib] results in decreased expression of ID3 mRNA
|
CTD |
PMID:39223679 |
|
NCBI chr 5:153,656,253...153,657,860
Ensembl chr 5:153,630,498...153,657,856
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|
| G
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Id4
|
inhibitor of DNA binding 4
|
multiple interactions
|
ISO
|
[Arsenic Trioxide results in decreased methylation of ID4 promoter] which results in increased expression of ID4 mRNA
|
CTD |
PMID:21223739 |
|
NCBI chr17:16,595,724...16,598,293
Ensembl chr17:16,595,724...16,598,492
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|
| G
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Idh1
|
isocitrate dehydrogenase (NADP(+)) 1
|
decreases expression
|
EXP
|
Arsenic Trioxide results in decreased expression of IDH1 mRNA
|
CTD |
PMID:29223816 |
|
NCBI chr 9:74,027,887...74,057,442
Ensembl chr 9:74,027,892...74,049,555
|
|
| G
|
Idh2
|
isocitrate dehydrogenase (NADP(+)) 2
|
decreases expression increases expression
|
EXP ISO
|
Arsenic Trioxide results in decreased expression of IDH2 mRNA Arsenic Trioxide results in increased expression of IDH2 protein
|
CTD |
PMID:25419056 PMID:29223816 |
|
NCBI chr 1:143,447,925...143,467,248
Ensembl chr 1:143,439,323...143,467,248
|
|
| G
|
Idnk
|
Idnk, gluconokinase
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to IDNK protein]
|
CTD |
PMID:26598702 |
|
NCBI chr17:6,489,397...6,496,520
Ensembl chr17:6,488,982...6,499,822
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|
| G
|
Ids
|
iduronate 2-sulfatase
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of IDS mRNA
|
CTD |
PMID:15761015 |
|
NCBI chr X:154,070,781...154,093,681
Ensembl chr X:154,070,781...154,091,444
|
|
| G
|
Ier2
|
immediate early response 2
|
affects expression
|
ISO
|
Arsenic Trioxide affects the expression of IER2 mRNA
|
CTD |
PMID:12749819 |
|
NCBI chr19:40,399,373...40,400,897
Ensembl chr19:40,398,160...40,402,708
|
|
| G
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Ier5l
|
immediate early response 5-like
|
decreases expression increases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of IER5L mRNA Arsenic Trioxide results in increased expression of IER5L mRNA
|
CTD |
PMID:20458559 PMID:39716349 |
|
NCBI chr 3:34,141,866...34,143,457
Ensembl chr 3:34,139,672...34,144,452
|
|
| G
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Ifi44
|
interferon-induced protein 44
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of IFI44 mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr 2:243,286,050...243,303,869
Ensembl chr 2:243,286,052...243,306,877
|
|
| G
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Ifih1
|
interferon induced with helicase C domain 1
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of IFIH1 mRNA
|
CTD |
PMID:15761015 |
|
NCBI chr 3:67,635,924...67,683,968
Ensembl chr 3:67,637,545...67,683,968
|
|
| G
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Ifit2
|
interferon-induced protein with tetratricopeptide repeats 2
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of IFIT2 mRNA
|
CTD |
PMID:26705709 |
|
NCBI chr 1:241,515,735...241,521,799
Ensembl chr 1:241,515,709...241,521,798
|
|
| G
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Ifit3
|
interferon-induced protein with tetratricopeptide repeats 3
|
multiple interactions
|
ISO
|
[Tretinoin co-treated with Arsenic Trioxide] results in increased expression of IFIT3 mRNA
|
CTD |
PMID:15894607 |
|
NCBI chr 1:241,527,326...241,532,469
Ensembl chr 1:241,526,880...241,532,521
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|
| G
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Ifitm3
|
interferon induced transmembrane protein 3
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of IFITM3 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 1:205,540,649...205,541,758
Ensembl chr 1:205,481,168...205,547,920
|
|
| G
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Ifnb1
|
interferon beta 1
|
multiple interactions decreases expression increases secretion
|
ISO
|
Arsenic Trioxide inhibits the reaction [Lipopolysaccharides results in increased expression of IFNB1 mRNA]; Arsenic Trioxide inhibits the reaction [Lipopolysaccharides results in increased expression of IFNB1 protein] Arsenic Trioxide results in decreased expression of IFNB1 mRNA Arsenic Trioxide results in increased secretion of IFNB1 protein
|
CTD |
PMID:23106696 PMID:38684648 |
|
NCBI chr 5:108,066,650...108,067,487
Ensembl chr 5:108,066,650...108,067,487
|
|
| G
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Ifng
|
interferon gamma
|
decreases expression multiple interactions increases expression increases activity affects expression
|
ISO EXP
|
Arsenic Trioxide results in decreased expression of IFNG mRNA; Arsenic Trioxide results in decreased expression of IFNG protein [Arsenic Trioxide co-treated with Cyclosporine] affects the expression of IFNG mRNA Arsenic Trioxide results in increased expression of IFNG mRNA; Arsenic Trioxide results in increased expression of IFNG protein Arsenic Trioxide results in increased activity of IFNG protein boric acid inhibits the reaction [Arsenic Trioxide results in increased expression of IFNG mRNA]; boric acid inhibits the reaction [Arsenic Trioxide results in increased expression of IFNG protein]; Phloretin inhibits the reaction [Arsenic Trioxide results in increased expression of IFNG protein] Arsenic Trioxide promotes the reaction [[IFNG protein results in increased activity of STAT1 protein] which results in increased expression of IRF1 mRNA]; Arsenic Trioxide promotes the reaction [IFNG protein results in increased activity of STAT1 protein]; Arsenic Trioxide promotes the reaction [IFNG protein results in increased expression of IRF1 mRNA]; Arsenic Trioxide promotes the reaction [IFNG protein results in increased expression of IRF1 protein]; Arsenic Trioxide promotes the reaction [IFNG protein results in increased phosphorylation of STAT1 protein]; CASP3 protein promotes the reaction [Arsenic Trioxide results in increased activity of IFNG protein] Arsenic Trioxide affects the expression of IFNG mRNA
|
CTD |
PMID:14668793 PMID:16914093 PMID:19545743 PMID:23802174 PMID:29049341 PMID:29159556 PMID:29950232 PMID:30368975 PMID:34037972 PMID:34108876 PMID:37166470 PMID:38684648 More...
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|
NCBI chr 7:55,789,180...55,793,216
Ensembl chr 7:55,761,736...55,793,216
|
|
| G
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Ifngr2
|
interferon gamma receptor 2
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of IFNGR2 mRNA
|
CTD |
PMID:29633893 |
|
NCBI chr11:44,265,703...44,283,975
Ensembl chr11:44,265,703...44,283,975
|
|
| G
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Ifrd1
|
interferon-related developmental regulator 1
|
decreases expression increases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of IFRD1 mRNA Arsenic Trioxide results in increased expression of IFRD1 mRNA
|
CTD |
PMID:17547211 PMID:20458559 PMID:24356939 |
|
NCBI chr 6:62,996,560...63,044,996
Ensembl chr 6:62,996,562...63,016,131
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| G
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Ift122
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intraflagellar transport 122
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decreases expression
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ISO
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Arsenic Trioxide results in decreased expression of IFT122 mRNA
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CTD |
PMID:39716349 |
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NCBI chr 4:150,577,525...150,648,052
Ensembl chr 4:150,539,786...150,648,052
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| G
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Ift140
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intraflagellar transport 140
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increases expression
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ISO
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Arsenic Trioxide results in increased expression of IFT140 mRNA
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CTD |
PMID:35676786 |
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NCBI chr10:14,537,134...14,624,926
Ensembl chr10:14,537,466...14,624,926
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| G
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Ift172
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intraflagellar transport 172
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multiple interactions
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ISO
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[Tretinoin co-treated with Arsenic Trioxide] results in decreased expression of IFT172 mRNA
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CTD |
PMID:15894607 |
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NCBI chr 6:30,801,841...30,841,239
Ensembl chr 6:30,801,918...30,840,830
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| G
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Igf1
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insulin-like growth factor 1
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affects response to substance decreases expression multiple interactions increases expression
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ISO EXP
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IGF1 mRNA affects the susceptibility to Arsenic Trioxide Arsenic Trioxide results in decreased expression of IGF1 mRNA Arsenic Trioxide inhibits the reaction [IGF1 protein results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Arsenic Trioxide inhibits the reaction [IGF1 protein results in increased phosphorylation of and results in increased activity of MAPK3 protein] Arsenic Trioxide results in increased expression of IGF1 mRNA Arsenic Trioxide results in decreased expression of IGF1 mRNA; Arsenic Trioxide results in decreased expression of IGF1 protein Phloretin inhibits the reaction [Arsenic Trioxide results in decreased expression of IGF1 mRNA]
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CTD |
PMID:18414637 PMID:20458559 PMID:23041229 PMID:23911876 PMID:31258454 PMID:34037972 More...
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NCBI chr 7:24,169,608...24,249,446
Ensembl chr 7:24,130,137...24,246,764
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| G
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Igf1r
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insulin-like growth factor 1 receptor
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decreases expression increases expression affects response to substance
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ISO
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Arsenic Trioxide results in decreased expression of IGF1R mRNA Arsenic Trioxide results in increased expression of IGF1R mRNA IGF1R mRNA affects the susceptibility to Arsenic Trioxide
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CTD |
PMID:19769630 PMID:23911876 PMID:24831965 |
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NCBI chr 1:130,959,787...131,248,664
Ensembl chr 1:130,959,997...131,248,664
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| G
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Igf2
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insulin-like growth factor 2
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multiple interactions increases expression decreases expression
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ISO EXP
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[Arsenic Trioxide co-treated with Curcumin] results in increased expression of IGF2 protein Arsenic Trioxide results in increased expression of IGF2 mRNA; Arsenic Trioxide results in increased expression of IGF2 protein Arsenic Trioxide results in decreased expression of IGF2 protein
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CTD |
PMID:25258189 PMID:27430728 PMID:31258454 |
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NCBI chr 1:207,243,873...207,261,263
Ensembl chr 1:207,243,873...207,260,667
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| G
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Igf2bp2
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insulin-like growth factor 2 mRNA binding protein 2
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decreases expression multiple interactions
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ISO
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Arsenic Trioxide results in decreased expression of IGF2BP2 mRNA IGF2BP2 protein promotes the reaction [Arsenic Trioxide inhibits the reaction [INS protein results in increased phosphorylation of GSK3B protein]]; IGF2BP2 protein promotes the reaction [Arsenic Trioxide results in increased expression of CASP1 protein modified form]; IGF2BP2 protein promotes the reaction [Arsenic Trioxide results in increased expression of NLRP3 protein]; IGF2BP2 protein promotes the reaction [Arsenic Trioxide results in increased secretion of IL18 protein]; IGF2BP2 protein promotes the reaction [Arsenic Trioxide results in increased secretion of IL1B protein]; IGF2BP2 protein promotes the reaction [Arsenic Trioxide results in increased stability of NLRP3 mRNA]
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CTD |
PMID:22521957 PMID:35226250 |
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NCBI chr11:92,378,908...92,478,893
Ensembl chr11:92,378,908...92,478,867
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| G
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Igf2r
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insulin-like growth factor 2 receptor
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decreases expression
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ISO
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Arsenic Trioxide results in decreased expression of IGF2R protein
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CTD |
PMID:25419056 |
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NCBI chr 1:50,526,878...50,615,265
Ensembl chr 1:50,526,878...50,615,265
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| G
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Igfals
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insulin-like growth factor binding protein, acid labile subunit
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decreases expression
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ISO
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Arsenic Trioxide results in decreased expression of IGFALS mRNA
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CTD |
PMID:35676786 |
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NCBI chr10:14,397,076...14,408,439
Ensembl chr10:14,403,399...14,407,138
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| G
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Igfbp1
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insulin-like growth factor binding protein 1
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increases expression multiple interactions
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ISO
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Arsenic Trioxide results in increased expression of IGFBP1 mRNA [Arsenic Trioxide co-treated with Curcumin] results in decreased expression of IGFBP1 protein
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CTD |
PMID:15073043 PMID:27430728 |
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NCBI chr14:86,261,277...86,266,344
Ensembl chr14:86,261,277...86,266,344
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| G
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Igfbp2
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insulin-like growth factor binding protein 2
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decreases expression multiple interactions
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ISO
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Arsenic Trioxide results in decreased expression of IGFBP2 mRNA [Arsenic Trioxide co-treated with Curcumin] results in decreased expression of IGFBP2 protein; Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to IGFBP2 protein]
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CTD |
PMID:15070760 PMID:15761015 PMID:26598702 PMID:27430728 |
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NCBI chr 9:81,864,811...81,892,179
Ensembl chr 9:81,864,783...81,892,171
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| G
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Igfbp3
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insulin-like growth factor binding protein 3
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multiple interactions increases expression
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ISO
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[Arsenic Trioxide co-treated with Curcumin] results in increased expression of IGFBP3 protein Arsenic Trioxide results in increased expression of IGFBP3 protein
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CTD |
PMID:27430728 |
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NCBI chr14:86,270,208...86,277,944
Ensembl chr14:86,270,208...86,277,944
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| G
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Igfbp4
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insulin-like growth factor binding protein 4
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increases expression multiple interactions
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ISO
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Arsenic Trioxide results in increased expression of IGFBP4 protein [Arsenic Trioxide co-treated with Curcumin] results in increased expression of IGFBP4 protein; [Tretinoin co-treated with Arsenic Trioxide] results in decreased expression of IGFBP4 mRNA
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CTD |
PMID:15894607 PMID:27430728 |
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NCBI chr10:84,491,471...84,503,487
Ensembl chr10:84,485,775...84,503,473
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| G
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Igfbp5
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insulin-like growth factor binding protein 5
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increases expression multiple interactions
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ISO
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Arsenic Trioxide results in increased expression of IGFBP5 protein [Arsenic Trioxide co-treated with Curcumin] results in increased expression of IGFBP5 protein
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CTD |
PMID:27430728 |
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NCBI chr 9:81,901,605...81,914,187
Ensembl chr 9:81,897,616...81,914,390
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| G
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Igfbp7
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insulin-like growth factor binding protein 7
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decreases expression multiple interactions
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ISO
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Arsenic Trioxide results in decreased expression of IGFBP7 mRNA Arsenic Trioxide inhibits the reaction [Dasatinib results in increased expression of IGFBP7 mRNA]
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CTD |
PMID:15725085 PMID:29266867 |
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NCBI chr14:31,091,681...31,151,623
Ensembl chr14:31,091,347...31,151,620
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| G
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Ighg1
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immunoglobulin heavy constant gamma 1
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decreases expression
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ISO
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Arsenic Trioxide results in decreased expression of IGHG1 mRNA
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CTD |
PMID:20458559 |
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| G
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Igkc
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immunoglobulin kappa constant
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multiple interactions
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ISO
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Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to IGKC protein]
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CTD |
PMID:26598702 |
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|
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| G
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Igsf6
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immunoglobulin superfamily, member 6
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decreases expression
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ISO
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Arsenic Trioxide results in decreased expression of IGSF6 mRNA
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CTD |
PMID:19128835 |
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NCBI chr 1:185,041,462...185,051,956
Ensembl chr 1:185,041,462...185,052,245
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| G
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Ihh
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Indian hedgehog signaling molecule
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increases expression
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ISO
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Arsenic Trioxide results in increased expression of IHH mRNA
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CTD |
PMID:29767511 |
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NCBI chr 9:83,952,986...83,959,203
Ensembl chr 9:83,952,986...83,959,203
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| G
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Ik
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IK cytokine
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increases expression
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ISO
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Arsenic Trioxide results in increased expression of IK mRNA
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CTD |
PMID:20458559 |
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NCBI chr18:28,632,025...28,646,829
Ensembl chr18:28,631,616...28,653,463
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| G
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Ikbkb
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inhibitor of nuclear factor kappa B kinase subunit beta
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increases expression decreases expression multiple interactions
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ISO
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Arsenic Trioxide results in increased expression of IKBKB mRNA Arsenic Trioxide results in decreased expression of IKBKB mRNA; Arsenic Trioxide results in decreased expression of IKBKB protein [Arsenic Trioxide results in increased phosphorylation of and results in increased activity of IKBKB protein] which results in increased phosphorylation of and results in increased ubiquitination of and results in increased degradation of CCND1 protein; Arsenic Trioxide results in increased phosphorylation of and results in increased activity of IKBKB protein; TNF protein inhibits the reaction [Arsenic Trioxide results in decreased expression of IKBKB mRNA]; TNF protein inhibits the reaction [Arsenic Trioxide results in decreased expression of IKBKB protein]
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CTD |
PMID:19763917 PMID:22988968 PMID:23949314 PMID:29633893 |
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NCBI chr16:76,021,968...76,075,717
Ensembl chr16:76,022,008...76,081,911
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| G
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Ikbkg
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inhibitor of nuclear factor kappa B kinase regulatory subunit gamma
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decreases expression
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ISO
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Arsenic Trioxide results in decreased expression of IKBKG mRNA
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CTD |
PMID:19763917 |
|
NCBI chr X:157,358,279...157,397,563
Ensembl chr X:157,367,639...157,392,757
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| G
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Il10
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interleukin 10
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multiple interactions decreases expression increases expression increases secretion
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ISO EXP
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Arsenic Trioxide affects the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of IL10 mRNA]; Arsenic Trioxide affects the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of IL10 protein]; ATF4 protein affects the reaction [Arsenic Trioxide results in increased expression of IL10 mRNA]; Taurine inhibits the reaction [Arsenic Trioxide results in increased expression of IL10 protein] Arsenic Trioxide results in decreased expression of IL10 mRNA; Arsenic Trioxide results in decreased expression of IL10 protein Arsenic Trioxide results in increased expression of IL10 mRNA; Arsenic Trioxide results in increased expression of IL10 protein Arsenic Trioxide results in increased secretion of IL10 protein dapagliflozin inhibits the reaction [Arsenic Trioxide results in decreased expression of IL10 protein]; Febuxostat inhibits the reaction [Arsenic Trioxide results in decreased expression of IL10 protein]; Nicorandil inhibits the reaction [Arsenic Trioxide results in decreased expression of IL10 protein]; Phloretin inhibits the reaction [Arsenic Trioxide results in decreased expression of IL10 protein]
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CTD |
PMID:23802174 PMID:27461142 PMID:28454374 PMID:30237538 PMID:34037972 PMID:34108876 PMID:37166470 PMID:37689273 PMID:38070468 PMID:38237221 PMID:38741475 More...
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NCBI chr13:45,024,921...45,029,586
Ensembl chr13:45,025,087...45,029,580
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| G
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Il11
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interleukin 11
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increases expression
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ISO
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Arsenic Trioxide results in increased expression of IL11 mRNA
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CTD |
PMID:22535156 |
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NCBI chr 1:78,098,622...78,104,915
Ensembl chr 1:78,096,930...78,104,915
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| G
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Il12rb2
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interleukin 12 receptor subunit beta 2
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increases expression
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ISO
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Arsenic Trioxide results in increased expression of IL12RB2 mRNA
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CTD |
PMID:15761015 |
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NCBI chr 4:97,756,089...97,844,937
Ensembl chr 4:97,756,089...97,844,937
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| G
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Il13
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interleukin 13
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decreases secretion decreases expression multiple interactions
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ISO
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Arsenic Trioxide results in decreased secretion of IL13 protein Arsenic Trioxide results in decreased expression of IL13 mRNA Arsenic Trioxide inhibits the reaction [GATA3 protein binds to IL13 promoter]
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CTD |
PMID:19080345 |
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NCBI chr10:38,290,926...38,293,483
Ensembl chr10:38,290,926...38,293,483
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| G
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Il15
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interleukin 15
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decreases expression increases expression
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ISO
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Arsenic Trioxide results in decreased expression of IL15 mRNA Arsenic Trioxide results in increased expression of IL15 mRNA
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CTD |
PMID:20458559 PMID:22521957 PMID:34108876 |
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NCBI chr19:42,536,160...42,611,349
Ensembl chr19:42,545,346...42,611,348
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| G
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Il17a
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interleukin 17A
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decreases expression decreases secretion
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ISO
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Arsenic Trioxide results in decreased expression of IL17A mRNA; Arsenic Trioxide results in decreased expression of IL17A protein Arsenic Trioxide results in decreased secretion of IL17A protein
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CTD |
PMID:29950232 PMID:34108876 |
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NCBI chr 9:30,640,844...30,644,331
Ensembl chr 9:30,640,844...30,644,331
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| G
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Il17rd
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interleukin 17 receptor D
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decreases expression
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ISO
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Arsenic Trioxide results in decreased expression of IL17RD mRNA
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CTD |
PMID:39716349 |
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NCBI chr16:2,235,172...2,489,827
Ensembl chr16:2,235,169...2,301,850
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| G
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Il18
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interleukin 18
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decreases expression increases secretion multiple interactions increases expression
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ISO
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Arsenic Trioxide results in decreased expression of IL18 Arsenic Trioxide results in increased secretion of IL18 protein IGF2BP2 protein promotes the reaction [Arsenic Trioxide results in increased secretion of IL18 protein]; METTL14 protein promotes the reaction [Arsenic Trioxide results in increased secretion of IL18 protein] Arsenic Trioxide results in increased expression of IL18 mRNA
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CTD |
PMID:20693187 PMID:35226250 PMID:36801614 |
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NCBI chr 8:59,802,072...59,829,275
Ensembl chr 8:59,809,592...59,831,286
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| G
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Il18r1
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interleukin 18 receptor 1
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decreases expression
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ISO
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Arsenic Trioxide results in decreased expression of IL18R1 mRNA
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CTD |
PMID:35676786 |
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NCBI chr 9:50,223,274...50,257,370
Ensembl chr 9:50,223,200...50,257,367
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| G
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Il19
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interleukin 19
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increases expression decreases expression
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ISO
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Arsenic Trioxide results in increased expression of IL19 mRNA Arsenic Trioxide results in decreased expression of IL19 protein
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CTD |
PMID:20458559 PMID:37166470 |
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NCBI chr13:44,949,989...44,958,714
Ensembl chr13:44,949,989...44,958,714
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| G
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Il1a
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interleukin 1 alpha
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increases expression decreases expression affects expression multiple interactions
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ISO EXP
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Arsenic Trioxide results in increased expression of IL1A mRNA Arsenic Trioxide results in decreased expression of IL1A mRNA Arsenic Trioxide affects the expression of IL1A mRNA Arsenic Trioxide results in increased expression of IL1A protein trans-sodium crocetinate inhibits the reaction [Arsenic Trioxide results in increased expression of IL1A protein]
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CTD |
PMID:17530438 PMID:22521957 PMID:31734849 PMID:33173984 |
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NCBI chr 3:136,979,804...136,990,236
Ensembl chr 3:136,979,805...136,998,013
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| G
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Il1b
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interleukin 1 beta
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increases expression multiple interactions decreases expression affects expression increases secretion
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ISO EXP
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Arsenic Trioxide results in increased expression of IL1B mRNA; Arsenic Trioxide results in increased expression of IL1B protein 3-methyladenine inhibits the reaction [[Arsenic Trioxide co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of IL1B protein]; [acetyl-11-ketoboswellic acid co-treated with Arsenic Trioxide] results in decreased secretion of IL1B protein; [Arsenic Trioxide co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of IL1B protein; Arsenic Trioxide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of IL1B protein]; Arsenic Trioxide promotes the reaction [Tretinoin results in increased expression of IL1B mRNA]; Arsenic Trioxide promotes the reaction [Tretinoin results in increased secretion of IL1B protein]; AS3MT mRNA promotes the reaction [Arsenic Trioxide results in increased expression of IL1B protein]; CA 074 methyl ester inhibits the reaction [[Arsenic Trioxide co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of IL1B protein]; IGF2BP2 protein promotes the reaction [Arsenic Trioxide results in increased secretion of IL1B protein]; METTL14 protein promotes the reaction [Arsenic Trioxide results in increased secretion of IL1B protein]; N-(1,2,3,5,6,7-hexahydro-S-indacen-4-ylcarbamoyl)-4-(2-hydroxy-2-propanyl)-2-furansulfonamide inhibits the reaction [[Arsenic Trioxide co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of IL1B protein]; Taurine inhibits the reaction [[Arsenic Trioxide co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of IL1B protein] Arsenic Trioxide results in decreased expression of IL1B; Arsenic Trioxide results in decreased expression of IL1B mRNA 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [Arsenic Trioxide results in increased expression of and results in increased secretion of IL1B protein]; [Arsenic Trioxide co-treated with Lipopolysaccharides] results in increased expression of IL1B protein; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [Arsenic Trioxide results in increased expression of and results in increased secretion of IL1B protein]; Arsenic Trioxide results in increased expression of and results in increased secretion of IL1B protein; boric acid inhibits the reaction [Arsenic Trioxide results in increased expression of IL1B mRNA]; boric acid inhibits the reaction [Arsenic Trioxide results in increased expression of IL1B protein]; dapagliflozin inhibits the reaction [Arsenic Trioxide results in increased expression of IL1B protein]; Febuxostat inhibits the reaction [Arsenic Trioxide results in increased expression of IL1B protein]; Lenalidomide inhibits the reaction [[Arsenic Trioxide co-treated with Lipopolysaccharides] results in increased expression of IL1B protein]; N-(1,2,3,5,6,7-hexahydro-S-indacen-4-ylcarbamoyl)-4-(2-hydroxy-2-propanyl)-2-furansulfonamide inhibits the reaction [[Arsenic Trioxide co-treated with Lipopolysaccharides] results in increased expression of IL1B protein]; NEAT1 mRNA affects the reaction [Arsenic Trioxide affects the expression of IL1B mRNA]; NEAT1 mRNA affects the reaction [Arsenic Trioxide affects the expression of IL1B protein]; Nicorandil inhibits the reaction [Arsenic Trioxide results in increased expression of IL1B protein]; polydatin inhibits the reaction [Arsenic Trioxide results in increased expression of IL1B mRNA]; pyrazolanthrone inhibits the reaction [Arsenic Trioxide results in increased expression of and results in increased secretion of IL1B protein]; Taurine inhibits the reaction [[Arsenic Trioxide co-treated with Lipopolysaccharides] results in increased expression of IL1B protein]; Taurine inhibits the reaction [Arsenic Trioxide results in increased expression of IL1B protein]; trans-sodium crocetinate inhibits the reaction [Arsenic Trioxide results in increased expression of IL1B protein] 18alpha,20beta-hydroxy-11-oxo-norolean-12-en-3beta-yl-2-O-beta-D-glucopyranurosyl-alpha-D-glucopyranosiduronate magnesium tetrahydrate inhibits the reaction [Arsenic Trioxide results in increased expression of IL1B mRNA]; 18alpha,20beta-hydroxy-11-oxo-norolean-12-en-3beta-yl-2-O-beta-D-glucopyranurosyl-alpha-D-glucopyranosiduronate magnesium tetrahydrate inhibits the reaction [Arsenic Trioxide results in increased expression of IL1B protein]; 2-aminoethoxydiphenyl borate inhibits the reaction [Arsenic Trioxide results in decreased expression of IL1B mRNA]; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid inhibits the reaction [Arsenic Trioxide results in decreased expression of IL1B mRNA]; [Arsenic Trioxide results in increased abundance of arsenite] which results in increased expression of IL1B protein; Arsenic Trioxide affects the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the cleavage of IL1B protein]; Arsenic Trioxide affects the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of IL1B mRNA]; Arsenic Trioxide inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of IL1B protein]; Arsenic Trioxide inhibits the reaction [anthrax toxin results in increased secretion of and results in increased cleavage of IL1B protein]; Arsenic Trioxide inhibits the reaction [Nigericin results in increased cleavage of IL1B protein]; Arsenic Trioxide promotes the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]; ATF4 protein affects the reaction [Arsenic Trioxide results in decreased expression of IL1B mRNA]; baicalin inhibits the reaction [Arsenic Trioxide results in increased expression of IL1B protein]; Plant Extracts inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic Trioxide] which results in increased expression of IL1B protein]; Quin2 inhibits the reaction [Arsenic Trioxide results in decreased expression of IL1B mRNA]; Taurine inhibits the reaction [Arsenic Trioxide results in increased expression of IL1B protein] Arsenic Trioxide affects the expression of IL1B mRNA; Arsenic Trioxide affects the expression of IL1B protein
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CTD |
PMID:20339114 PMID:20458559 PMID:20693187 PMID:21078271 PMID:22535156 PMID:23253724 PMID:23430110 PMID:24337744 PMID:26892147 PMID:27174766 PMID:27461142 PMID:29130132 PMID:30237538 PMID:30368975 PMID:30660605 PMID:31734849 PMID:32096187 PMID:32226249 PMID:32240679 PMID:32919218 PMID:33603344 PMID:33846815 PMID:35088608 PMID:35226250 PMID:35317438 PMID:35676786 PMID:36791901 PMID:37689273 PMID:38070468 PMID:38237221 PMID:38684648 PMID:38741475 More...
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NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601
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| G
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Il1f10
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interleukin 1 family member 10
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multiple interactions
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ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to IL1F10 protein]
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CTD |
PMID:26598702 |
|
NCBI chr 3:27,470,798...27,473,726
Ensembl chr 3:27,470,798...27,473,726
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| G
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Il1r2
|
interleukin 1 receptor type 2
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increases expression
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ISO
|
Arsenic Trioxide results in increased expression of IL1R2 mRNA
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CTD |
PMID:21461292 PMID:37969188 |
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NCBI chr 9:49,879,928...49,920,374
Ensembl chr 9:49,877,266...49,920,374
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| G
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Il1rn
|
interleukin 1 receptor antagonist
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multiple interactions decreases response to substance decreases expression
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ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to IL1RN protein] IL1RN protein results in decreased susceptibility to Arsenic Trioxide Arsenic Trioxide results in decreased expression of IL1RN mRNA
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CTD |
PMID:19128835 PMID:26598702 PMID:27174766 |
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NCBI chr 3:27,509,836...27,525,738
Ensembl chr 3:27,509,798...27,525,732
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| G
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Il2
|
interleukin 2
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decreases expression multiple interactions increases expression
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ISO EXP
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Arsenic Trioxide results in decreased expression of IL2 mRNA; Arsenic Trioxide results in decreased expression of IL2 protein [Arsenic Trioxide results in increased abundance of arsenite] which results in increased expression of IL2 protein Phloretin inhibits the reaction [Arsenic Trioxide results in increased expression of IL2 protein]
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CTD |
PMID:23802174 PMID:29049341 PMID:34037972 PMID:34108876 PMID:36791901 PMID:37166470 More...
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|
NCBI chr 2:121,932,968...121,937,672
Ensembl chr 2:121,932,968...121,937,672
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| G
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Il20rb
|
interleukin 20 receptor subunit beta
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increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of IL20RB mRNA
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CTD |
PMID:26705709 |
|
NCBI chr 8:109,858,108...109,896,066
Ensembl chr 8:109,854,012...109,889,363
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|
| G
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Il22ra1
|
interleukin 22 receptor subunit alpha 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of IL22RA1 mRNA
|
CTD |
PMID:22521957 |
|
NCBI chr 5:153,245,067...153,269,865
Ensembl chr 5:153,245,002...153,271,683
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| G
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Il23a
|
interleukin 23 subunit alpha
|
decreases expression
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ISO
|
Arsenic Trioxide results in decreased expression of IL23A
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CTD |
PMID:20693187 |
|
NCBI chr 7:1,306,320...1,308,434
Ensembl chr 7:1,306,320...1,308,434
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| G
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Il24
|
interleukin 24
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increases activity multiple interactions
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ISO
|
Arsenic Trioxide results in increased activity of IL24 protein [Arsenic Trioxide co-treated with IL24 protein] results in decreased expression of BCL2L1; [Arsenic Trioxide co-treated with IL24 protein] results in decreased expression of CASP3; [Arsenic Trioxide co-treated with IL24 protein] results in decreased expression of PARP1; [IL24 protein co-treated with Arsenic Trioxide] results in increased phosphorylation of MAPK1 protein; [IL24 protein co-treated with Arsenic Trioxide] results in increased phosphorylation of MAPK3 protein; [IL24 protein co-treated with Arsenic Trioxide] results in increased phosphorylation of MAPK7 protein; [IL24 protein co-treated with Arsenic Trioxide] results in increased phosphorylation of MAPK8 protein; [IL24 protein co-treated with Arsenic Trioxide] results in increased phosphorylation of MAPK9 protein
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CTD |
PMID:12883035 PMID:14678967 PMID:15580305 |
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NCBI chr13:44,905,362...44,910,760
Ensembl chr13:44,905,363...44,910,760
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| G
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Il27ra
|
interleukin 27 receptor subunit alpha
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of IL27RA mRNA
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CTD |
PMID:19128835 |
|
NCBI chr19:41,014,730...41,026,740
Ensembl chr19:41,014,730...41,026,760
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| G
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Il2ra
|
interleukin 2 receptor subunit alpha
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of IL2RA mRNA
|
CTD |
PMID:34108876 |
|
NCBI chr17:71,759,802...71,808,475
Ensembl chr17:71,759,802...71,808,507
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| G
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Il36a
|
interleukin 36, alpha
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to IL36A protein]
|
CTD |
PMID:26598702 |
|
NCBI chr 3:27,395,146...27,399,695
Ensembl chr 3:27,395,146...27,399,695
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| G
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Il3ra
|
interleukin 3 receptor subunit alpha
|
multiple interactions decreases expression
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to IL3RA protein] Arsenic Trioxide results in decreased expression of IL3RA mRNA; Arsenic Trioxide results in decreased expression of IL3RA protein
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CTD |
PMID:24791595 PMID:26598702 |
|
NCBI chr12:21,431,848...21,437,336
Ensembl chr12:21,431,848...21,437,250
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| G
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Il4
|
interleukin 4
|
decreases expression affects expression
|
ISO
|
Arsenic Trioxide results in decreased expression of IL4 protein Arsenic Trioxide results in decreased expression of IL4 mRNA Arsenic Trioxide affects the expression of IL4 protein
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CTD |
PMID:12243866 PMID:15073043 PMID:18357729 PMID:29950232 |
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NCBI chr10:38,272,003...38,277,549
Ensembl chr10:38,272,003...38,277,549
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| G
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Il4r
|
interleukin 4 receptor
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of IL4R mRNA
|
CTD |
PMID:12243866 PMID:22521957 |
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NCBI chr 1:189,545,739...189,570,639
Ensembl chr 1:189,544,988...189,570,636
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| G
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Il6
|
interleukin 6
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decreases expression increases expression multiple interactions increases secretion decreases secretion affects expression
|
EXP ISO
|
Arsenic Trioxide results in decreased expression of IL6 mRNA Arsenic Trioxide results in increased expression of IL6 protein Arsenic Trioxide results in increased expression of IL6 mRNA; Arsenic Trioxide results in increased expression of IL6 protein 18alpha,20beta-hydroxy-11-oxo-norolean-12-en-3beta-yl-2-O-beta-D-glucopyranurosyl-alpha-D-glucopyranosiduronate magnesium tetrahydrate inhibits the reaction [Arsenic Trioxide results in increased expression of IL6 mRNA]; 18alpha,20beta-hydroxy-11-oxo-norolean-12-en-3beta-yl-2-O-beta-D-glucopyranurosyl-alpha-D-glucopyranosiduronate magnesium tetrahydrate inhibits the reaction [Arsenic Trioxide results in increased expression of IL6 protein]; 3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [Arsenic Trioxide results in increased expression of IL6 mRNA]; [Arsenic Trioxide results in increased abundance of arsenite] which results in increased expression of IL6 protein; Arsenic Trioxide affects the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of IL6 mRNA]; Arsenic Trioxide affects the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of IL6 protein]; baicalin inhibits the reaction [Arsenic Trioxide results in increased expression of IL6 protein]; pyrazolanthrone promotes the reaction [Arsenic Trioxide results in increased expression of IL6 mRNA]; Taurine inhibits the reaction [Arsenic Trioxide results in increased expression of IL6 protein]; Thioctic Acid inhibits the reaction [Arsenic Trioxide results in increased expression of IL6 mRNA] 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Arsenic Trioxide results in increased expression of and results in increased secretion of IL6 protein]; [Folic Acid co-treated with Vitamin B 12] inhibits the reaction [Arsenic Trioxide results in increased expression of IL6 protein]; Arsenic Trioxide results in increased expression of and results in increased secretion of IL6 protein; crocin inhibits the reaction [Arsenic Trioxide results in increased expression of IL6 mRNA]; crocin inhibits the reaction [Arsenic Trioxide results in increased expression of IL6 protein]; dapagliflozin inhibits the reaction [Arsenic Trioxide results in increased expression of IL6 protein]; Diosgenin inhibits the reaction [Arsenic Trioxide results in increased expression of and results in increased secretion of IL6 protein]; Febuxostat inhibits the reaction [Arsenic Trioxide results in increased expression of IL6 protein]; NEAT1 mRNA affects the reaction [Arsenic Trioxide affects the expression of IL6 mRNA]; NEAT1 mRNA affects the reaction [Arsenic Trioxide affects the expression of IL6 protein]; Nicorandil inhibits the reaction [Arsenic Trioxide results in increased expression of IL6 protein]; NR3C1 promotes the reaction [Diosgenin inhibits the reaction [Arsenic Trioxide results in increased expression of and results in increased secretion of IL6 protein]]; Phloretin inhibits the reaction [Arsenic Trioxide results in increased expression of IL6 protein]; trans-sodium crocetinate inhibits the reaction [Arsenic Trioxide results in increased expression of IL6 protein] [Arsenic Trioxide co-treated with IFNA2 protein] results in decreased expression of IL6 mRNA; Arsenic Trioxide inhibits the reaction [IL6 protein results in increased phosphorylation of and results in increased activity of STAT3 protein]; Arsenic Trioxide inhibits the reaction [IL6 protein results in increased phosphorylation of JAK1 protein]; Arsenic Trioxide inhibits the reaction [IL6 protein results in increased phosphorylation of JAK2 protein]; Arsenic Trioxide results in decreased susceptibility to and results in decreased expression of IL6 protein; MIR491 mRNA promotes the reaction [Arsenic Trioxide results in decreased expression of IL6 mRNA] Arsenic Trioxide results in increased secretion of IL6 protein Arsenic Trioxide results in decreased secretion of IL6 protein Arsenic Trioxide affects the expression of IL6 mRNA; Arsenic Trioxide affects the expression of IL6 protein
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CTD |
PMID:12492118 PMID:12560223 PMID:16214333 PMID:22465848 PMID:22488045 PMID:24140498 PMID:25196641 PMID:25873331 PMID:27664319 PMID:30237538 PMID:30612216 PMID:32096187 PMID:32920515 PMID:33173984 PMID:33603344 PMID:33846815 PMID:34037972 PMID:34108876 PMID:34333357 PMID:35088608 PMID:35317438 PMID:36791901 PMID:37689273 PMID:38070468 PMID:38237221 PMID:38741475 PMID:39059093 More...
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|
NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610
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| G
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Il6st
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interleukin 6 cytokine family signal transducer
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of IL6ST mRNA
|
CTD |
PMID:15073043 |
|
NCBI chr 2:45,798,872...45,839,501
Ensembl chr 2:45,799,380...45,843,182
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| G
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Il7r
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interleukin 7 receptor
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increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of IL7R protein
|
CTD |
PMID:34108876 |
|
NCBI chr 2:60,179,561...60,204,937
Ensembl chr 2:60,181,382...60,211,027
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| G
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Ilkap
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ILK associated serine/threonine phosphatase
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to ILKAP protein]
|
CTD |
PMID:26598702 |
|
NCBI chr 9:99,413,981...99,436,262
Ensembl chr 9:99,413,978...99,436,418
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| G
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Impa2
|
inositol monophosphatase 2
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of IMPA2 mRNA
|
CTD |
PMID:29633893 |
|
NCBI chr18:63,104,113...63,135,232
Ensembl chr18:63,104,083...63,137,543
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| G
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Impdh2
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inosine monophosphate dehydrogenase 2
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of IMPDH2 mRNA
|
CTD |
PMID:22521957 |
|
NCBI chr 8:118,135,204...118,139,892
Ensembl chr 8:118,135,262...118,139,873
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| G
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Ing2
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inhibitor of growth family, member 2
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decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of ING2 mRNA
|
CTD |
PMID:35676786 |
|
NCBI chr16:51,305,311...51,316,177
Ensembl chr16:51,307,466...51,316,177
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| G
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Ing5
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inhibitor of growth family, member 5
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increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of ING5 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 9:101,772,845...101,793,734
Ensembl chr 9:101,773,724...101,793,728
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| G
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Inhba
|
inhibin subunit beta A
|
decreases expression multiple interactions
|
ISO
|
Arsenic Trioxide results in decreased expression of INHBA mRNA [Arsenic Trioxide co-treated with Tretinoin] results in decreased expression of INHBA mRNA
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CTD |
PMID:20458559 PMID:38179723 |
|
NCBI chr17:53,787,159...53,810,942
Ensembl chr17:53,791,444...53,804,508
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| G
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Inhbb
|
inhibin subunit beta B
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of INHBB mRNA
|
CTD |
PMID:29633893 |
|
NCBI chr13:33,083,671...33,089,373
Ensembl chr13:33,083,671...33,089,609
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| G
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Inhbc
|
inhibin subunit beta C
|
multiple interactions
|
ISO
|
[Arsenic Trioxide co-treated with apatinib] results in increased expression of INHBC mRNA
|
CTD |
PMID:39223679 |
|
NCBI chr 7:65,069,450...65,082,919
Ensembl chr 7:65,069,451...65,082,919
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| G
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Inhbe
|
inhibin subunit beta E
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increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of INHBE mRNA
|
CTD |
PMID:27829220 |
|
NCBI chr 7:65,061,531...65,064,519
Ensembl chr 7:65,061,531...65,064,519
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| G
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Inip
|
INTS3 and NABP interacting protein
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increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of INIP mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr 5:79,443,317...79,457,552
Ensembl chr 5:79,443,317...79,457,552
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| G
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Inka1
|
inka box actin regulator 1
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of INKA1 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 8:117,552,875...117,554,565
Ensembl chr 8:117,552,875...117,554,565
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| G
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Ino80
|
INO80 complex ATPase subunit
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of INO80 mRNA
|
CTD |
PMID:29633893 |
|
NCBI chr 3:126,822,280...126,919,532
Ensembl chr 3:126,822,280...126,919,532
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| G
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Inpp1
|
inositol polyphosphate-1-phosphatase
|
decreases response to substance
|
ISO
|
INPP1 protein results in decreased susceptibility to Arsenic Trioxide
|
CTD |
PMID:20707922 |
|
NCBI chr 9:56,161,816...56,209,774
Ensembl chr 9:56,161,852...56,234,569
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| G
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Inpp5b
|
inositol polyphosphate-5-phosphatase B
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of INPP5B mRNA
|
CTD |
PMID:15761015 |
|
NCBI chr 5:142,281,454...142,345,993
Ensembl chr 5:142,281,418...142,345,991
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| G
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Inppl1
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inositol polyphosphate phosphatase-like 1
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increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of INPPL1 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 1:165,595,047...165,609,503
Ensembl chr 1:165,595,063...165,609,503
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| G
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Ins1
|
insulin 1
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decreases secretion increases expression decreases expression multiple interactions
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ISO EXP
|
Arsenic Trioxide results in decreased secretion of INS1 protein Arsenic Trioxide results in increased expression of INS1 protein Arsenic Trioxide results in decreased expression of INS1 protein 7-methyl-5-(1-((3-(trifluoromethyl)phenyl)acetyl)-2,3-dihydro-1H-indol-5-yl)-7H-pyrrolo(2,3-d)pyrimidin-4-amine inhibits the reaction [Arsenic Trioxide inhibits the reaction [Glucose results in increased secretion of INS1 protein]]; [Estrogens deficiency co-treated with Arsenic Trioxide] inhibits the reaction [INS1 protein results in decreased abundance of Blood Glucose]; [Estrogens deficiency co-treated with Arsenic Trioxide] results in increased expression of INS1 protein; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in decreased secretion of INS1 protein]; Arsenic Trioxide inhibits the reaction [Estradiol promotes the reaction [Glucose results in increased secretion of INS1 protein]]; Arsenic Trioxide inhibits the reaction [Glucose results in increased secretion of INS1 protein]; Arsenic Trioxide promotes the reaction [Estrogens deficiency inhibits the reaction [Glucose results in increased secretion of INS1 protein]]; Estradiol inhibits the reaction [[Arsenic Trioxide co-treated with Estrogens deficiency] inhibits the reaction [INS1 protein results in decreased abundance of Blood Glucose]]; Estradiol inhibits the reaction [[Estrogens deficiency co-treated with Arsenic Trioxide] results in increased expression of INS1 protein]; Estradiol inhibits the reaction [Arsenic Trioxide promotes the reaction [Estrogens deficiency inhibits the reaction [Glucose results in increased secretion of INS1 protein]]] Arsenic Trioxide inhibits the reaction [[Glucose co-treated with Lipopolysaccharides] results in increased secretion of INS1 protein]; Lenalidomide inhibits the reaction [Arsenic Trioxide inhibits the reaction [[Glucose co-treated with Lipopolysaccharides] results in increased secretion of INS1 protein]]; N-(1,2,3,5,6,7-hexahydro-S-indacen-4-ylcarbamoyl)-4-(2-hydroxy-2-propanyl)-2-furansulfonamide inhibits the reaction [Arsenic Trioxide inhibits the reaction [[Glucose co-treated with Lipopolysaccharides] results in increased secretion of INS1 protein]]; Taurine inhibits the reaction [Arsenic Trioxide inhibits the reaction [[Glucose co-treated with Lipopolysaccharides] results in increased secretion of INS1 protein]]
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CTD |
PMID:21145380 PMID:25859628 PMID:29111283 PMID:30385301 PMID:30660605 PMID:31332900 More...
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NCBI chr 1:261,186,119...261,186,686
Ensembl chr 1:261,186,119...261,186,682
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| G
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Ins2
|
insulin 2
|
multiple interactions
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ISO
|
Arsenic Trioxide inhibits the reaction [INS protein results in increased phosphorylation of GSK3B protein]; Plant Extracts inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic Trioxide] which results in decreased expression of INS2 protein] Arsenic Trioxide inhibits the reaction [INS protein results in increased phosphorylation of GSK3B protein]; AS3MT mRNA promotes the reaction [Arsenic Trioxide inhibits the reaction [INS protein results in increased phosphorylation of GSK3B protein]]; IGF2BP2 protein promotes the reaction [Arsenic Trioxide inhibits the reaction [INS protein results in increased phosphorylation of GSK3B protein]]; INS protein inhibits the reaction [[Arsenic Trioxide co-treated with Glucose] results in increased expression of AQP7 mRNA]; INS protein inhibits the reaction [[Arsenic Trioxide co-treated with Glucose] results in increased expression of AQP7 protein]; METTL14 protein promotes the reaction [Arsenic Trioxide inhibits the reaction [INS protein results in increased phosphorylation of GSK3B protein]]; N-(1,2,3,5,6,7-hexahydro-S-indacen-4-ylcarbamoyl)-4-(2-hydroxy-2-propanyl)-2-furansulfonamide inhibits the reaction [Arsenic Trioxide inhibits the reaction [INS protein results in increased phosphorylation of GSK3B protein]]
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CTD |
PMID:32226249 PMID:35226250 PMID:37146668 |
|
NCBI chr 1:207,272,738...207,421,998
Ensembl chr 1:207,272,742...207,273,805
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| G
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Insig1
|
insulin induced gene 1
|
multiple interactions decreases expression
|
ISO
|
[Tretinoin co-treated with Arsenic Trioxide] results in decreased expression of INSIG1 mRNA Arsenic Trioxide results in decreased expression of INSIG1 mRNA
|
CTD |
PMID:15894607 |
|
NCBI chr 4:8,049,339...8,057,812
Ensembl chr 4:8,049,556...8,057,778
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|
| G
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Insm1
|
INSM transcriptional repressor 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of INSM1 mRNA
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CTD |
PMID:15761015 |
|
NCBI chr 3:154,093,310...154,096,243
Ensembl chr 3:154,092,734...154,096,047
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|
| G
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Insrr
|
insulin receptor-related receptor
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of INSRR mRNA
|
CTD |
PMID:35676786 |
|
NCBI chr 2:175,553,244...175,572,676
Ensembl chr 2:175,553,293...175,572,676
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|
| G
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Ints6
|
integrator complex subunit 6
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of INTS6 mRNA
|
CTD |
PMID:20458559 PMID:35676786 |
|
NCBI chr15:41,080,584...41,224,350
Ensembl chr15:41,109,125...41,197,519
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| G
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Iqch
|
IQ motif containing H
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of IQCH mRNA
|
CTD |
PMID:15761015 |
|
NCBI chr 8:72,784,932...72,978,632
Ensembl chr 8:72,787,756...72,978,598
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|
| G
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Irak1
|
interleukin-1 receptor-associated kinase 1
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of IRAK1 mRNA
|
CTD |
PMID:23911876 |
|
NCBI chr X:156,919,927...156,929,825
Ensembl chr X:156,920,081...156,929,825
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| G
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Irf1
|
interferon regulatory factor 1
|
decreases expression multiple interactions increases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of IRF1 mRNA Arsenic Trioxide promotes the reaction [[IFNG protein results in increased activity of STAT1 protein] which results in increased expression of IRF1 mRNA]; Arsenic Trioxide promotes the reaction [IFNG protein results in increased expression of IRF1 mRNA]; Arsenic Trioxide promotes the reaction [IFNG protein results in increased expression of IRF1 protein] Arsenic Trioxide results in increased expression of IRF1 mRNA
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CTD |
PMID:14668793 PMID:16914093 PMID:20458559 PMID:20953137 PMID:22521957 |
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NCBI chr10:38,417,935...38,424,946
Ensembl chr10:38,417,148...38,424,947
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| G
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Irf3
|
interferon regulatory factor 3
|
multiple interactions increases phosphorylation
|
ISO
|
Arsenic Trioxide inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of IRF3 protein]; STING1 promotes the reaction [Arsenic Trioxide results in increased phosphorylation of IRF3 protein]
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CTD |
PMID:23106696 PMID:38684648 |
|
NCBI chr 1:104,616,608...104,621,402
Ensembl chr 1:104,616,469...104,621,401
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|
| G
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Irf4
|
interferon regulatory factor 4
|
affects methylation increases expression
|
ISO
|
Arsenic Trioxide affects the methylation of IRF4 promoter Arsenic Trioxide results in increased expression of IRF4 mRNA
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CTD |
PMID:26046465 PMID:35676786 |
|
NCBI chr17:33,930,460...33,948,842
Ensembl chr17:33,930,471...33,948,730
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| G
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Irf6
|
interferon regulatory factor 6
|
decreases response to substance
|
ISO
|
IRF6 protein results in decreased susceptibility to Arsenic Trioxide
|
CTD |
PMID:20707922 |
|
NCBI chr13:107,200,876...107,220,083
Ensembl chr13:107,200,731...107,220,049
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|
| G
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Irf7
|
interferon regulatory factor 7
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of IRF7 mRNA; Arsenic Trioxide results in decreased expression of IRF7 protein
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CTD |
PMID:32642412 |
|
NCBI chr 1:205,796,956...205,800,543
Ensembl chr 1:205,796,959...205,800,023
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|
| G
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Irf8
|
interferon regulatory factor 8
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of IRF8 mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr19:65,699,284...65,721,066
Ensembl chr19:65,699,284...65,721,062
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|
| G
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Irs1
|
insulin receptor substrate 1
|
increases phosphorylation decreases expression affects response to substance multiple interactions
|
ISO
|
Arsenic Trioxide results in increased phosphorylation of IRS1 protein Arsenic Trioxide results in decreased expression of IRS1 mRNA IRS1 mRNA affects the susceptibility to Arsenic Trioxide 3-methyladenine inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of IRS1 protein]; Palmitic Acid inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of IRS1 protein]; Rosiglitazone inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of IRS1 protein]; Taurine inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of IRS1 protein]
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CTD |
PMID:20458559 PMID:23911876 PMID:30362509 |
|
NCBI chr 9:91,001,137...91,053,959
Ensembl chr 9:90,993,519...91,054,538
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|
| G
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Isg15
|
ISG15 ubiquitin-like modifier
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of ISG15 protein
|
CTD |
PMID:19364129 |
|
NCBI chr 5:172,066,369...172,067,656
Ensembl chr 5:172,066,369...172,067,656
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|
| G
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Isl2
|
ISL LIM homeobox 2
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of ISL2 mRNA
|
CTD |
PMID:24356939 |
|
NCBI chr 8:64,819,879...64,824,864
Ensembl chr 8:64,819,879...64,824,864
|
|
| G
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Islr2
|
immunoglobulin superfamily containing leucine-rich repeat 2
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of ISLR2 mRNA
|
CTD |
PMID:35676786 |
|
NCBI chr 8:67,504,042...67,512,125
Ensembl chr 8:67,504,037...67,513,708
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|
| G
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Itga2
|
integrin subunit alpha 2
|
decreases response to substance decreases expression
|
ISO
|
ITGA2 protein results in decreased susceptibility to Arsenic Trioxide Arsenic Trioxide results in decreased expression of ITGA2 mRNA
|
CTD |
PMID:20707922 PMID:25258189 |
|
NCBI chr 2:48,253,412...48,354,509
Ensembl chr 2:48,253,412...48,354,509
|
|
| G
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Itga2b
|
integrin subunit alpha 2b
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of ITGA2B mRNA
|
CTD |
PMID:15761015 |
|
NCBI chr10:87,908,697...87,926,225
Ensembl chr10:87,908,697...87,925,833
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| G
|
Itga4
|
integrin subunit alpha 4
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of ITGA4 mRNA
|
CTD |
PMID:26238599 |
|
NCBI chr 3:84,569,487...84,646,276
Ensembl chr 3:84,560,369...84,641,039
|
|
| G
|
Itga6
|
integrin subunit alpha 6
|
increases expression multiple interactions
|
ISO
|
Arsenic Trioxide results in increased expression of ITGA6 mRNA [Tretinoin co-treated with Arsenic Trioxide] results in decreased expression of ITGA6 mRNA
|
CTD |
PMID:15894607 PMID:29633893 |
|
NCBI chr 3:77,012,168...77,097,076
Ensembl chr 3:77,017,766...77,097,076
|
|
| G
|
Itga9
|
integrin subunit alpha 9
|
decreases expression increases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of ITGA9 mRNA Arsenic Trioxide results in increased expression of ITGA9 mRNA
|
CTD |
PMID:26705709 PMID:35676786 |
|
NCBI chr 8:127,185,244...127,493,296
Ensembl chr 8:127,169,226...127,493,296
|
|
| G
|
Itgam
|
integrin subunit alpha M
|
decreases expression increases expression multiple interactions
|
ISO
|
Arsenic Trioxide results in decreased expression of ITGAM protein Arsenic Trioxide results in increased expression of ITGAM mRNA; Arsenic Trioxide results in increased expression of ITGAM protein 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [[Sirolimus co-treated with Arsenic Trioxide] results in increased expression of ITGAM protein]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Arsenic Trioxide results in increased expression of ITGAM protein]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Gefitinib promotes the reaction [Arsenic Trioxide results in increased expression of ITGAM protein]]; [Arsenic Trioxide co-treated with Tretinoin] results in increased expression of ITGAM protein; [Sirolimus co-treated with Arsenic Trioxide] results in increased expression of ITGAM protein; [Tretinoin co-treated with Arsenic Trioxide] results in increased expression of ITGAM mRNA; AG 1879 promotes the reaction [[Arsenic Trioxide co-treated with Tretinoin] results in increased expression of ITGAM protein]; Arsenic Trioxide promotes the reaction [Tretinoin results in increased expression of ITGAM protein]; Gefitinib promotes the reaction [Arsenic Trioxide results in increased expression of ITGAM mRNA]; Gefitinib promotes the reaction [Arsenic Trioxide results in increased expression of ITGAM protein] ATF4 protein affects the reaction [Arsenic Trioxide results in decreased expression of ITGAM protein]
|
CTD |
PMID:10648417 PMID:16174796 PMID:16430862 PMID:16468075 PMID:20226526 PMID:20609355 PMID:20615082 PMID:24953245 PMID:25758096 PMID:27461142 PMID:32587277 More...
|
|
NCBI chr 1:192,089,496...192,139,947
Ensembl chr 1:192,089,542...192,139,943
|
|
| G
|
Itgav
|
integrin subunit alpha V
|
multiple interactions
|
ISO
|
[Arsenic Trioxide co-treated with Bortezomib] results in decreased expression of ITGAV mRNA
|
CTD |
PMID:25913414 |
|
NCBI chr 3:89,245,382...89,333,512
Ensembl chr 3:89,245,095...89,333,511
|
|
| G
|
Itgax
|
integrin subunit alpha X
|
decreases expression multiple interactions increases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of ITGAX protein RELA protein inhibits the reaction [Arsenic Trioxide results in decreased expression of ITGAX protein] Arsenic Trioxide results in increased expression of ITGAX protein
|
CTD |
PMID:16174796 PMID:32587277 |
|
NCBI chr 1:192,140,089...192,171,151
Ensembl chr 1:192,149,905...192,171,151
|
|
| G
|
Itgb1
|
integrin subunit beta 1
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of ITGB1 mRNA
|
CTD |
PMID:12852829 PMID:26238599 |
|
NCBI chr19:73,602,277...73,650,271
Ensembl chr19:73,602,126...73,650,269
|
|
| G
|
Itgb1bp1
|
integrin subunit beta 1 binding protein 1
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of ITGB1BP1 mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr 6:46,549,994...46,564,735
Ensembl chr 6:46,549,999...46,564,398
|
|
| G
|
Itgb2
|
integrin subunit beta 2
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of ITGB2 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr20:11,061,009...11,097,242
Ensembl chr20:11,058,492...11,097,182
|
|
| G
|
Itgb3
|
integrin subunit beta 3
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of ITGB3 protein
|
CTD |
PMID:16360329 |
|
NCBI chr10:90,009,927...90,067,787
Ensembl chr10:90,009,900...90,067,800
|
|
| G
|
Itgb3bp
|
integrin subunit beta 3 binding protein
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of ITGB3BP mRNA
|
CTD |
PMID:17547211 |
|
NCBI chr 5:119,575,657...119,640,974
Ensembl chr 5:119,575,248...119,640,997
|
|
| G
|
Itgb4
|
integrin subunit beta 4
|
decreases response to substance increases expression
|
ISO
|
ITGB4 protein results in decreased susceptibility to Arsenic Trioxide Arsenic Trioxide results in increased expression of ITGB4 mRNA
|
CTD |
PMID:20707922 PMID:39716349 |
|
NCBI chr10:101,705,592...101,741,933
Ensembl chr10:101,705,587...101,741,932
|
|
| G
|
Itgb7
|
integrin subunit beta 7
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of ITGB7 mRNA
|
CTD |
PMID:15761015 |
|
NCBI chr 7:135,225,962...135,243,522
Ensembl chr 7:135,226,555...135,243,597
|
|
| G
|
Itgbl1
|
integrin subunit beta like 1
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of ITGBL1 mRNA
|
CTD |
PMID:26705709 |
|
NCBI chr15:107,186,792...107,448,335
Ensembl chr15:107,186,689...107,451,098
|
|
| G
|
Itih1
|
inter-alpha trypsin inhibitor, heavy chain 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of ITIH1 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr16:6,128,696...6,142,813
Ensembl chr16:6,128,698...6,142,853
|
|
| G
|
Itm2a
|
integral membrane protein 2A
|
decreases expression multiple interactions
|
ISO
|
Arsenic Trioxide results in decreased expression of ITM2A mRNA [Tretinoin co-treated with Arsenic Trioxide] results in decreased expression of ITM2A mRNA
|
CTD |
PMID:15725085 PMID:15894607 PMID:26705709 |
|
NCBI chr X:76,559,183...76,565,144
Ensembl chr X:76,559,181...76,565,437
|
|
| G
|
Itm2b
|
integral membrane protein 2B
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of ITM2B mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr15:54,955,549...54,978,455
Ensembl chr15:54,955,552...54,978,455
|
|
| G
|
Itpr1
|
inositol 1,4,5-trisphosphate receptor, type 1
|
multiple interactions increases phosphorylation decreases expression increases expression
|
ISO
|
2-aminoethyl diphenylborinate inhibits the reaction [Arsenic Trioxide results in increased expression of ITPR1 protein modified form]; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid inhibits the reaction [Arsenic Trioxide results in increased expression of ITPR1 protein modified form]; ATF4 protein promotes the reaction [Arsenic Trioxide results in increased expression of ITPR1 protein modified form] Arsenic Trioxide results in increased phosphorylation of ITPR1 protein Arsenic Trioxide results in decreased expression of ITPR1 mRNA Arsenic Trioxide results in increased expression of ITPR1 mRNA
|
CTD |
PMID:24831965 PMID:27461142 PMID:27638049 PMID:27829220 |
|
NCBI chr 4:142,743,401...143,066,505
Ensembl chr 4:142,743,334...143,066,504
|
|
| G
|
Itpr2
|
inositol 1,4,5-trisphosphate receptor, type 2
|
multiple interactions decreases expression increases expression
|
ISO
|
antimony trichloride promotes the reaction [Arsenic Trioxide results in increased expression of ITPR2 mRNA]; Arsenic Trioxide promotes the reaction [antimony trichloride results in increased expression of ITPR2 mRNA]; Metformin inhibits the reaction [Arsenic Trioxide results in decreased expression of ITPR2 mRNA] Arsenic Trioxide results in increased expression of ITPR2 protein
|
CTD |
PMID:29095437 PMID:30093655 PMID:34091186 |
|
NCBI chr 4:180,759,325...181,165,361
Ensembl chr 4:180,760,442...181,164,763
|
|
| G
|
Itprid2
|
ITPR interacting domain containing 2
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of ITPRID2 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 3:84,943,572...84,980,993
Ensembl chr 3:84,939,808...84,980,899
|
|
| G
|
Ivl
|
involucrin
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of IVL protein
|
CTD |
PMID:25419056 |
|
NCBI chr 2:180,842,307...180,854,646
Ensembl chr 2:180,842,307...180,846,578
|
|
| G
|
Jag2
|
jagged canonical Notch ligand 2
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of JAG2 mRNA
|
CTD |
PMID:23497375 |
|
NCBI chr 6:137,804,133...137,826,738
Ensembl chr 6:137,804,133...137,826,738
|
|
| G
|
Jak1
|
Janus kinase 1
|
multiple interactions increases phosphorylation decreases expression
|
ISO EXP
|
Arsenic Trioxide inhibits the reaction [IL6 protein results in increased phosphorylation of JAK1 protein]; Arsenic Trioxide results in decreased expression of and results in decreased phosphorylation of JAK1 protein; JAK1 protein inhibits the reaction [Arsenic Trioxide results in decreased expression of NFKB1 protein]; JAK1 protein inhibits the reaction [Arsenic Trioxide results in decreased expression of RELA protein] Arsenic Trioxide results in increased phosphorylation of JAK1 protein Arsenic Trioxide results in decreased expression of JAK1 mRNA Arsenic Trioxide affects the expression of and affects the phosphorylation of JAK1 protein; Nicorandil affects the reaction [Arsenic Trioxide affects the expression of and affects the phosphorylation of JAK1 protein]
|
CTD |
PMID:12492118 PMID:19951532 PMID:33634982 PMID:38741475 PMID:39716349 |
|
NCBI chr 5:120,895,606...121,004,207
Ensembl chr 5:120,896,046...120,996,758
|
|
| G
|
Jak2
|
Janus kinase 2
|
increases expression multiple interactions decreases expression decreases phosphorylation increases phosphorylation
|
ISO
|
Arsenic Trioxide results in increased expression of JAK2 mRNA [ruxolitinib co-treated with Arsenic Trioxide] results in decreased phosphorylation of JAK2 protein; Arsenic Trioxide inhibits the reaction [IL6 protein results in increased phosphorylation of JAK2 protein]; Arsenic Trioxide promotes the reaction [Curcumin results in decreased expression of JAK2 protein]; pervanadate inhibits the reaction [Arsenic Trioxide results in decreased phosphorylation of JAK2 protein]; PTPN6 protein affects the reaction [Arsenic Trioxide results in decreased phosphorylation of JAK2 protein] Arsenic Trioxide results in decreased expression of JAK2 protein Arsenic Trioxide results in increased phosphorylation of JAK2 protein baicalin promotes the reaction [Arsenic Trioxide results in increased phosphorylation of JAK2 protein]
|
CTD |
PMID:11721366 PMID:12492118 PMID:29409467 PMID:29633893 PMID:30012499 PMID:35088608 PMID:36352148 More...
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|
NCBI chr 1:236,408,905...236,468,769
Ensembl chr 1:236,408,662...236,468,762
|
|
| G
|
Jak3
|
Janus kinase 3
|
multiple interactions decreases expression
|
ISO
|
[Arsenic Trioxide co-treated with Decitabine] results in decreased expression of JAK3 mRNA Arsenic Trioxide results in decreased expression of JAK3 mRNA
|
CTD |
PMID:24762999 |
|
NCBI chr16:18,418,807...18,432,515
Ensembl chr16:18,420,415...18,433,222
|
|
| G
|
Jam2
|
junctional adhesion molecule 2
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of JAM2 mRNA
|
CTD |
PMID:27829220 |
|
NCBI chr11:37,316,287...37,366,517
Ensembl chr11:37,317,511...37,367,510
|
|
| G
|
Jarid2
|
jumonji and AT-rich interaction domain containing 2
|
increases response to substance
|
ISO
|
JARID2 protein results in increased susceptibility to Arsenic Trioxide
|
CTD |
PMID:20707922 |
|
NCBI chr17:19,983,217...20,163,598
Ensembl chr17:19,983,217...20,161,970
|
|
| G
|
Jkamp
|
JNK1/MAPK8-associated membrane protein
|
increases expression multiple interactions
|
ISO
|
Arsenic Trioxide results in increased expression of JKAMP mRNA Metformin inhibits the reaction [Arsenic Trioxide results in increased expression of JKAMP mRNA]
|
CTD |
PMID:29095437 |
|
NCBI chr 6:96,383,976...96,397,917
Ensembl chr 6:96,366,624...96,398,432
|
|
| G
|
Josd2
|
Josephin domain containing 2
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to JOSD2 protein]
|
CTD |
PMID:26598702 |
|
NCBI chr 1:104,097,382...104,101,271
Ensembl chr 1:104,097,376...104,101,277
|
|
| G
|
Jph2
|
junctophilin 2
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of JPH2 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 3:172,414,246...172,478,678
Ensembl chr 3:172,414,256...172,478,348
|
|
| G
|
Jpt1
|
Jupiter microtubule associated homolog 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of JPT1 mRNA
|
CTD |
PMID:22521957 |
|
NCBI chr10:101,243,428...101,261,464
Ensembl chr10:101,243,424...101,261,469
|
|
| G
|
Jpx
|
JPX transcript, XIST activator
|
affects expression
|
ISO
|
Arsenic Trioxide affects the expression of JPX mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr X:72,577,163...72,730,887
|
|
| G
|
Jun
|
Jun proto-oncogene, AP-1 transcription factor subunit
|
decreases expression multiple interactions affects response to substance increases activity affects expression increases expression increases phosphorylation decreases phosphorylation affects phosphorylation
|
ISO EXP
|
Arsenic Trioxide results in decreased expression of JUN mRNA; Arsenic Trioxide results in decreased expression of JUN protein Arsenic Trioxide promotes the reaction [Berberine affects the localization of JUN protein] JUN mRNA affects the susceptibility to Arsenic Trioxide Arsenic Trioxide results in increased activity of JUN protein Arsenic Trioxide affects the expression of JUN mRNA Arsenic Trioxide results in increased expression of JUN mRNA; Arsenic Trioxide results in increased expression of JUN protein; Arsenic Trioxide results in increased expression of JUN protein modified form 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of JUN protein]; [[Arsenic Trioxide results in increased phosphorylation of JUN protein] which binds to HDAC1 protein] which binds to CDKN1A promoter; [Arsenic Trioxide co-treated with Bortezomib] results in decreased expression of JUN mRNA; [Arsenic Trioxide co-treated with Bortezomib] results in increased activity of JUN protein modified form; [Arsenic Trioxide results in increased phosphorylation of and results in increased activity of JUN protein] which results in decreased expression of CDKN1A mRNA; [Arsenic Trioxide results in increased phosphorylation of JUN protein] which binds to HDAC1 protein; [Arsenic Trioxide results in increased phosphorylation of JUN protein] which results in decreased expression of CDKN1A; [Arsenic Trioxide results in increased phosphorylation of JUN protein] which results in decreased expression of CDKN1A mRNA; [Ethacrynic Acid co-treated with Arsenic Trioxide] results in increased phosphorylation of JUN protein; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of JUN protein]; Arsenic Trioxide promotes the reaction [[FOS protein binds to JUN promoter] which binds to CDKN1A promoter]; Arsenic Trioxide promotes the reaction [[FOS protein binds to JUN protein] which results in increased expression of CDKN1A mRNA]; Arsenic Trioxide promotes the reaction [[JUN protein binds to CDKN1A promoter] which results in increased expression of CDKN1A protein]; Arsenic Trioxide promotes the reaction [JUN protein binds to TGIF1 protein]; Arsenic Trioxide promotes the reaction [nilotinib results in increased expression of JUN mRNA]; Arsenic Trioxide promotes the reaction [nilotinib results in increased expression of JUN protein]; Arsenic Trioxide promotes the reaction [Tretinoin results in decreased expression of JUN protein]; Arsenic Trioxide results in increased expression of and results in increased phosphorylation of JUN protein; Arsenic Trioxide results in increased phosphorylation of and results in increased activity of JUN protein; benzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketone inhibits the reaction [PRAM1 protein promotes the reaction [Arsenic Trioxide results in increased phosphorylation of JUN protein]]; Dasatinib promotes the reaction [Arsenic Trioxide results in increased phosphorylation of JUN protein]; HMOX1 protein inhibits the reaction [Arsenic Trioxide results in increased expression of JUN protein modified form]; HMOX1 protein inhibits the reaction [Arsenic Trioxide results in increased expression of JUN protein]; JUN protein promotes the reaction [Arsenic Trioxide results in increased expression of HMOX1 protein]; JUN protein promotes the reaction [Arsenic Trioxide results in increased expression of MMP9 mRNA]; JUN protein promotes the reaction [Arsenic Trioxide results in increased expression of MMP9 protein]; PRAM1 protein promotes the reaction [Arsenic Trioxide results in increased phosphorylation of JUN protein]; pyrazolanthrone inhibits the reaction [[Ethacrynic Acid co-treated with Arsenic Trioxide] results in increased phosphorylation of JUN protein]; pyrazolanthrone inhibits the reaction [Arsenic Trioxide results in increased expression of JUN protein]; Tretinoin promotes the reaction [Arsenic Trioxide results in decreased expression of JUN protein]; zinc protoporphyrin promotes the reaction [Arsenic Trioxide results in increased expression of JUN protein] Arsenic Trioxide results in decreased phosphorylation of JUN protein Arsenic Trioxide affects the phosphorylation of JUN protein Arsenic Trioxide promotes the reaction [Lipopolysaccharides results in increased phosphorylation of and results in increased activity of JUN protein]
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CTD |
PMID:12749819 PMID:15637062 PMID:16646077 PMID:17495969 PMID:18210215 PMID:18294404 PMID:18633430 PMID:18822310 PMID:19410645 PMID:20074581 PMID:20471514 PMID:21278055 PMID:21655183 PMID:22521957 PMID:23082001 PMID:23106696 PMID:23883479 PMID:23911876 PMID:24934751 PMID:24956101 PMID:25174355 PMID:25258189 PMID:25335113 PMID:25574600 PMID:25913414 PMID:27829220 PMID:29266867 PMID:29442453 PMID:30093655 More...
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|
NCBI chr 5:115,009,900...115,012,993
Ensembl chr 5:114,973,151...115,013,285
|
|
| G
|
Junb
|
JunB proto-oncogene, AP-1 transcription factor subunit
|
multiple interactions decreases expression increases expression
|
ISO
|
Arsenic Trioxide promotes the reaction [nilotinib results in increased expression of JUNB mRNA]; Arsenic Trioxide promotes the reaction [nilotinib results in increased expression of JUNB protein] Arsenic Trioxide results in decreased expression of JUNB mRNA Arsenic Trioxide results in increased expression of JUNB mRNA; Arsenic Trioxide results in increased expression of JUNB protein
|
CTD |
PMID:19410645 PMID:20458559 PMID:23883479 PMID:25258189 |
|
NCBI chr19:40,081,126...40,082,910
Ensembl chr19:40,073,541...40,085,218
|
|
| G
|
Jund
|
JunD proto-oncogene, AP-1 transcription factor subunit
|
multiple interactions increases expression
|
ISO
|
[Arsenic Trioxide co-treated with IFNA2 protein co-treated with Docosahexaenoic Acids co-treated with Emodin] results in decreased expression of JUND protein Arsenic Trioxide results in increased expression of JUND mRNA
|
CTD |
PMID:15761015 PMID:17077332 |
|
NCBI chr16:18,768,093...18,769,771
Ensembl chr16:18,764,985...18,782,148
|
|
| G
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Kalrn
|
kalirin, RhoGEF kinase
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of KALRN mRNA
|
CTD |
PMID:20458559 PMID:26705709 |
|
NCBI chr11:79,703,345...80,309,210
Ensembl chr11:79,703,366...80,133,329
|
|
| G
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Kank2
|
KN motif and ankyrin repeat domains 2
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of KANK2 mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr 8:28,587,770...28,617,212
Ensembl chr 8:28,587,770...28,616,993
|
|
| G
|
Kank4
|
KN motif and ankyrin repeat domains 4
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of KANK4 mRNA
|
CTD |
PMID:26705709 |
|
NCBI chr 5:118,516,994...118,581,024
Ensembl chr 5:118,517,971...118,581,002
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|
| G
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Kansl1
|
KAT8 regulatory NSL complex subunit 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of KANSL1 mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr10:89,737,637...89,868,620
Ensembl chr10:89,737,637...89,868,620
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|
| G
|
Kat2a
|
lysine acetyltransferase 2A
|
affects expression
|
ISO
|
Arsenic Trioxide affects the expression of KAT2A mRNA
|
CTD |
PMID:25574600 |
|
NCBI chr10:86,132,535...86,140,877
Ensembl chr10:86,132,535...86,140,485
|
|
| G
|
Kat2b
|
lysine acetyltransferase 2B
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of KAT2B mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 9:6,799,101...6,903,616
Ensembl chr 9:6,799,145...6,903,616
|
|
| G
|
Kat5
|
lysine acetyltransferase 5
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of KAT5 mRNA
|
CTD |
PMID:19763917 |
|
NCBI chr 1:212,325,089...212,332,640
Ensembl chr 1:212,325,090...212,332,587
|
|
| G
|
Kat6b
|
lysine acetyltransferase 6B
|
decreases expression increases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of KAT6B mRNA Arsenic Trioxide results in increased expression of KAT6B mRNA
|
CTD |
PMID:15761015 PMID:20458559 |
|
NCBI chr15:2,688,535...2,861,443
Ensembl chr15:2,688,811...2,844,343
|
|
| G
|
Kat8
|
lysine acetyltransferase 8
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of KAT8 mRNA
|
CTD |
PMID:22521957 |
|
NCBI chr 1:191,954,827...191,967,107
Ensembl chr 1:191,954,438...191,967,105
|
|
| G
|
Kbtbd11
|
kelch repeat and BTB domain containing 11
|
multiple interactions
|
ISO
|
[Tretinoin co-treated with Arsenic Trioxide] results in decreased expression of KBTBD11 mRNA
|
CTD |
PMID:15894607 |
|
NCBI chr16:81,318,596...81,340,334
Ensembl chr16:81,313,093...81,340,390
|
|
| G
|
Kcnb1
|
potassium voltage-gated channel subfamily B member 1
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of KCNB1 mRNA
|
CTD |
PMID:35676786 |
|
NCBI chr 3:176,239,285...176,332,408
Ensembl chr 3:176,242,589...176,332,408
|
|
| G
|
Kcng1
|
potassium voltage-gated channel modifier subfamily G member 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of KCNG1 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 3:177,379,593...177,412,986
Ensembl chr 3:177,392,031...177,411,507
|
|
| G
|
Kcnh2
|
potassium voltage-gated channel subfamily H member 2
|
decreases localization increases expression increases degradation decreases expression decreases activity multiple interactions
|
ISO EXP
|
Arsenic Trioxide results in decreased localization of KCNH2 protein Arsenic Trioxide results in increased expression of KCNH2 mRNA Arsenic Trioxide results in increased degradation of KCNH2 protein Arsenic Trioxide results in decreased expression of KCNH2 protein Arsenic Trioxide results in decreased activity of KCNH2 protein Arsenic Trioxide affects the expression of and results in increased activity of KCNH2 protein; Arsenic Trioxide results in decreased expression of and affects the localization of and results in decreased activity of KCNH2 protein; Astemizole inhibits the reaction [Arsenic Trioxide results in increased degradation of KCNH2 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Arsenic Trioxide results in increased degradation of KCNH2 protein]; fexofenadine inhibits the reaction [Arsenic Trioxide results in decreased expression of KCNH2 protein]; fexofenadine inhibits the reaction [Arsenic Trioxide results in increased degradation of KCNH2 protein]; MALAT1 protein affects the reaction [Arsenic Trioxide results in decreased activity of KCNH2 protein]; Matrines inhibits the reaction [Arsenic Trioxide results in decreased localization of KCNH2 protein]; MIR21 mRNA promotes the reaction [Arsenic Trioxide results in decreased expression of KCNH2 protein]; MIR23A mRNA promotes the reaction [Arsenic Trioxide results in decreased expression of and affects the localization of and results in decreased activity of KCNH2 protein]; oxymatrine inhibits the reaction [Arsenic Trioxide results in decreased localization of KCNH2 protein]; Ranolazine inhibits the reaction [Arsenic Trioxide results in increased degradation of KCNH2 protein]; Resveratrol inhibits the reaction [Arsenic Trioxide results in decreased activity of KCNH2 protein]
|
CTD |
PMID:15070760 PMID:15213294 PMID:22977528 PMID:23103450 PMID:25107562 PMID:25395240 PMID:28521025 PMID:30127993 PMID:40041754 More...
|
|
NCBI chr 4:11,719,357...11,751,424
Ensembl chr 4:11,692,980...11,751,421
|
|
| G
|
Kcnip4
|
potassium voltage-gated channel interacting protein 4
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of KCNIP4 mRNA
|
CTD |
PMID:26705709 |
|
NCBI chr14:65,593,297...66,743,994
Ensembl chr14:65,593,366...66,743,993
|
|
| G
|
Kcnj3
|
potassium inwardly-rectifying channel, subfamily J, member 3
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of KCNJ3 mRNA
|
CTD |
PMID:26705709 |
|
NCBI chr 3:60,353,990...60,518,110
Ensembl chr 3:60,354,146...60,518,104
|
|
| G
|
Kcnk12
|
potassium two pore domain channel subfamily K member 12
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of KCNK12 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 6:12,492,609...12,544,250
Ensembl chr 6:12,494,850...12,544,221
|
|
| G
|
Kcnk2
|
potassium two pore domain channel subfamily K member 2
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of KCNK2 mRNA
|
CTD |
PMID:26705709 |
|
NCBI chr13:103,297,387...103,494,686
Ensembl chr13:103,297,393...103,494,686
|
|
| G
|
Kcnk6
|
potassium two pore domain channel subfamily K member 6
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of KCNK6 mRNA
|
CTD |
PMID:22521957 |
|
NCBI chr 1:93,652,888...93,661,419
|
|
| G
|
Kcnma1
|
potassium calcium-activated channel subfamily M alpha 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of KCNMA1 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr15:351,065...1,057,117
Ensembl chr15:351,659...1,057,117
|
|
| G
|
Kcnn2
|
potassium calcium-activated channel subfamily N member 2
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of KCNN2 mRNA
|
CTD |
PMID:26705709 |
|
NCBI chr18:40,004,693...40,445,043
Ensembl chr18:40,155,939...40,445,045
|
|
| G
|
Kcns3
|
potassium voltage-gated channel, modifier subfamily S, member 3
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of KCNS3 mRNA
|
CTD |
PMID:26705709 |
|
NCBI chr 6:39,527,410...39,584,105
Ensembl chr 6:39,523,777...39,618,848
|
|
| G
|
Kcnu1
|
potassium calcium-activated channel subfamily U member 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of KCNU1 mRNA
|
CTD |
PMID:26705709 |
|
NCBI chr16:72,844,692...72,932,216
Ensembl chr16:72,844,712...72,932,334
|
|
| G
|
Kcnv2
|
potassium voltage-gated channel modifier subfamily V member 2
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of KCNV2 mRNA
|
CTD |
PMID:35676786 |
|
NCBI chr 1:234,409,067...234,485,894
Ensembl chr 1:234,413,096...234,495,298
|
|
| G
|
Kcp
|
kielin cysteine rich BMP regulator
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of KCP mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr 4:59,048,209...59,083,522
Ensembl chr 4:59,047,968...59,083,531
|
|
| G
|
Kctd12
|
potassium channel tetramerization domain containing 12
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of KCTD12 mRNA
|
CTD |
PMID:15761015 PMID:25258189 PMID:39716349 |
|
NCBI chr15:86,214,786...86,220,725
Ensembl chr15:86,214,840...86,224,539
|
|
| G
|
Kctd20
|
potassium channel tetramerization domain containing 20
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of KCTD20 mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr20:7,017,480...7,034,440
Ensembl chr20:7,017,502...7,034,441
|
|
| G
|
Kctd5
|
potassium channel tetramerization domain containing 5
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to KCTD5 protein]
|
CTD |
PMID:26598702 |
|
NCBI chr10:13,583,781...13,609,762
Ensembl chr10:13,583,781...13,610,062
|
|
| G
|
Kctd6
|
potassium channel tetramerization domain containing 6
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of KCTD6 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr15:19,125,529...19,142,038
Ensembl chr15:19,124,932...19,134,583
|
|
| G
|
Kctd9
|
potassium channel tetramerization domain containing 9
|
increases expression multiple interactions
|
ISO
|
Arsenic Trioxide results in increased expression of KCTD9 mRNA Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to KCTD9 protein]
|
CTD |
PMID:20458559 PMID:26598702 |
|
NCBI chr15:46,117,211...46,145,258
Ensembl chr15:46,117,874...46,145,266
|
|
| G
|
Kdelr3
|
KDEL endoplasmic reticulum protein retention receptor 3
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of KDELR3 mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr 7:112,959,632...112,969,858
Ensembl chr 7:112,959,718...112,969,858
|
|
| G
|
Kdm1a
|
lysine demethylase 1A
|
multiple interactions
|
ISO
|
[Valproic Acid co-treated with Arsenic Trioxide] results in increased expression of KDM1A mRNA; [Valproic Acid co-treated with Arsenic Trioxide] results in increased expression of KDM1A protein
|
CTD |
PMID:25815518 |
|
NCBI chr 5:154,066,436...154,121,913
Ensembl chr 5:154,065,543...154,121,775
|
|
| G
|
Kdm2a
|
lysine demethylase 2A
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of KDM2A mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 1:211,041,859...211,125,749
Ensembl chr 1:211,041,885...211,084,479
|
|
| G
|
Kdm3a
|
lysine demethylase 3A
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of KDM3A mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 4:105,189,208...105,233,526
Ensembl chr 4:105,189,208...105,233,370
|
|
| G
|
Kdm7a
|
lysine demethylase 7A
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of KDM7A mRNA
|
CTD |
PMID:26705709 PMID:35676786 |
|
NCBI chr 4:68,866,263...68,992,979
Ensembl chr 4:68,871,677...68,931,506
|
|
| G
|
Kdr
|
kinase insert domain receptor
|
decreases expression increases expression multiple interactions
|
ISO
|
Arsenic Trioxide results in decreased expression of KDR; Arsenic Trioxide results in decreased expression of KDR mRNA; Arsenic Trioxide results in decreased expression of KDR protein Arsenic Trioxide results in increased expression of KDR gene mutant form [Arsenic Trioxide co-treated with apatinib] results in decreased expression of KDR mRNA; [Arsenic Trioxide co-treated with apatinib] results in decreased expression of KDR protein
|
CTD |
PMID:18161919 PMID:25088040 PMID:30014256 PMID:38275666 PMID:38746032 PMID:39223679 More...
|
|
NCBI chr14:32,572,031...32,615,204
Ensembl chr14:32,572,049...32,615,192
|
|
| G
|
Kdsr
|
3-ketodihydrosphingosine reductase
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of KDSR mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr13:23,374,101...23,408,779
Ensembl chr13:23,376,779...23,408,897
|
|
| G
|
Keap1
|
Kelch-like ECH-associated protein 1
|
increases response to substance multiple interactions increases expression decreases response to substance decreases expression affects response to substance
|
ISO EXP
|
KEAP1 mRNA results in increased susceptibility to Arsenic Trioxide [Tretinoin co-treated with Arsenic Trioxide] results in increased expression of KEAP1 mRNA; Arsenic Trioxide affects the reaction [KEAP1 protein results in increased expression of CCND1 protein]; KEAP1 mRNA inhibits the reaction [Ethionamide results in increased susceptibility to Arsenic Trioxide]; KEAP1 protein inhibits the reaction [Arsenic Trioxide results in decreased expression of CCND1 mRNA]; KEAP1 protein inhibits the reaction [Arsenic Trioxide results in increased expression of PPARG mRNA]; KEAP1 protein inhibits the reaction [Arsenic Trioxide results in increased expression of PPARG protein]; KEAP1 protein promotes the reaction [Rosiglitazone results in increased susceptibility to Arsenic Trioxide]; KEAP1 protein promotes the reaction [Troglitazone results in increased susceptibility to Arsenic Trioxide]; NFE2L2 protein promotes the reaction [Arsenic Trioxide results in increased expression of KEAP1 protein] Arsenic Trioxide results in increased expression of KEAP1 mRNA KEAP1 protein results in decreased susceptibility to Arsenic Trioxide Arsenic Trioxide results in decreased expression of KEAP1 protein KEAP1 gene mutant form affects the susceptibility to Arsenic Trioxide Arsenic Trioxide results in increased expression of KEAP1 mRNA; Arsenic Trioxide results in increased expression of KEAP1 protein crocin inhibits the reaction [Arsenic Trioxide results in decreased expression of KEAP1 protein] 18alpha,20beta-hydroxy-11-oxo-norolean-12-en-3beta-yl-2-O-beta-D-glucopyranurosyl-alpha-D-glucopyranosiduronate magnesium tetrahydrate inhibits the reaction [Arsenic Trioxide results in increased expression of KEAP1 protein]
|
CTD |
PMID:15894607 PMID:19417148 PMID:22684020 PMID:24634002 PMID:26708503 PMID:29223816 PMID:30815697 PMID:32920515 PMID:33846815 PMID:39152142 More...
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|
NCBI chr 8:28,044,555...28,054,042
Ensembl chr 8:28,044,555...28,054,042
|
|
| G
|
Khdc4
|
KH domain containing 4, pre-mRNA splicing factor
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of KHDC4 mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr 2:176,446,895...176,475,405
Ensembl chr 2:176,446,910...176,475,392
|
|
| G
|
Khk
|
ketohexokinase
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to KHK protein]
|
CTD |
PMID:26598702 |
|
NCBI chr 6:31,165,246...31,175,779
Ensembl chr 6:31,165,248...31,175,481
|
|
| G
|
Kiaa0232
|
KIAA0232 homolog
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of D5ERTD579E mRNA
|
CTD |
PMID:35676786 |
|
NCBI chr14:78,318,660...78,384,012
Ensembl chr14:78,319,105...78,384,014
|
|
| G
|
Kiaa0319l
|
KIAA0319 like
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of KIAA0319L mRNA
|
CTD |
PMID:27829220 |
|
NCBI chr 5:144,332,242...144,425,182
Ensembl chr 5:144,332,207...144,425,190
|
|
| G
|
Kif13b
|
kinesin family member 13B
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of KIF13B mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr15:43,084,059...43,241,719
Ensembl chr15:43,080,910...43,241,719
|
|
| G
|
Kif21b
|
kinesin family member 21B
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of KIF21B mRNA
|
CTD |
PMID:15761015 PMID:24356939 |
|
NCBI chr13:50,127,842...50,177,822
Ensembl chr13:50,127,842...50,177,822
|
|
| G
|
Kif27
|
kinesin family member 27
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of KIF27 mRNA
|
CTD |
PMID:25258189 |
|
NCBI chr17:6,304,960...6,383,745
Ensembl chr17:6,304,989...6,375,182
|
|
| G
|
Kif3a
|
kinesin family member 3a
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of KIF3A mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr10:38,226,388...38,263,062
Ensembl chr10:38,226,741...38,260,516
|
|
| G
|
Kifc2
|
kinesin family member C2
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of KIFC2 mRNA
|
CTD |
PMID:22521957 |
|
NCBI chr 7:110,261,257...110,269,007
Ensembl chr 7:110,261,009...110,269,005
|
|
| G
|
Kit
|
KIT proto-oncogene receptor tyrosine kinase
|
decreases phosphorylation increases expression decreases expression multiple interactions
|
ISO
|
Arsenic Trioxide results in decreased phosphorylation of KIT protein Arsenic Trioxide results in increased expression of KIT gene mutant form; Arsenic Trioxide results in increased expression of KIT mRNA Arsenic Trioxide results in decreased expression of KIT protein Arsenic Trioxide promotes the reaction [[GLI3 protein binds to KIT promoter] which results in decreased expression of KIT mRNA]; Arsenic Trioxide promotes the reaction [GLI3 protein binds to KIT promoter] Arsenic Trioxide results in decreased expression of KIT mRNA; Arsenic Trioxide results in decreased expression of KIT protein modified form
|
CTD |
PMID:19619438 PMID:19950550 PMID:20609355 PMID:23815908 PMID:26705709 PMID:27793025 PMID:38746032 More...
|
|
NCBI chr14:32,901,615...32,978,895
Ensembl chr14:32,903,033...32,978,812
|
|
| G
|
Kitlg
|
KIT ligand
|
decreases response to substance decreases expression increases expression
|
ISO
|
KITLG protein results in decreased susceptibility to Arsenic Trioxide Arsenic Trioxide results in decreased expression of KITLG mRNA Arsenic Trioxide results in increased expression of KITLG mRNA
|
CTD |
PMID:15761015 PMID:16360329 PMID:20458559 PMID:26705709 |
|
NCBI chr 7:36,782,621...36,863,796
Ensembl chr 7:36,782,638...36,863,793
|
|
| G
|
Kl
|
Klotho
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of KL mRNA
|
CTD |
PMID:27829220 |
|
NCBI chr12:5,326,003...5,367,016
Ensembl chr12:5,325,959...5,367,015
|
|
| G
|
Klc3
|
kinesin light chain 3
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of KLC3 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 1:88,173,842...88,183,806
Ensembl chr 1:88,173,404...88,184,253
|
|
| G
|
Klf11
|
KLF transcription factor 11
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of KLF11 mRNA
|
CTD |
PMID:15761015 |
|
NCBI chr 6:47,014,312...47,026,152
Ensembl chr 6:47,014,326...47,037,044
|
|
| G
|
Klf13
|
KLF transcription factor 13
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of KLF13 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 1:126,917,671...126,948,436
Ensembl chr 1:126,916,781...126,961,056
|
|
| G
|
Klf2
|
KLF transcription factor 2
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of KLF2 mRNA
|
CTD |
PMID:26705709 |
|
NCBI chr16:17,555,136...17,557,768
Ensembl chr16:17,555,136...17,557,768
|
|
| G
|
Klf3
|
KLF transcription factor 3
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of KLF3 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr14:43,828,387...43,859,418
Ensembl chr14:43,828,387...43,850,826
|
|
| G
|
Klf4
|
KLF transcription factor 4
|
multiple interactions decreases response to substance increases expression
|
ISO
|
[Arsenic Trioxide co-treated with Tretinoin] results in decreased expression of KLF4 protein; Arsenic Trioxide promotes the reaction [MSI1 protein results in increased expression of KLF4 protein]; EIF2AK2 protein affects the reaction [Arsenic Trioxide promotes the reaction [MSI1 protein results in increased expression of KLF4 protein]]; EIF2AK2 protein affects the reaction [Arsenic Trioxide results in increased expression of KLF4 protein]; EIF2S1 protein affects the reaction [Arsenic Trioxide promotes the reaction [MSI1 protein results in increased expression of KLF4 protein]]; MSI1 protein affects the reaction [Arsenic Trioxide results in increased expression of KLF4 protein] KLF4 protein results in decreased susceptibility to Arsenic Trioxide
|
CTD |
PMID:20707922 PMID:29486283 PMID:30093655 |
|
NCBI chr 5:75,074,107...75,079,182
Ensembl chr 5:75,074,236...75,078,592
|
|
| G
|
Klf5
|
KLF transcription factor 5
|
increases expression decreases response to substance
|
ISO
|
Arsenic Trioxide results in increased expression of KLF5 mRNA KLF5 protein results in decreased susceptibility to Arsenic Trioxide
|
CTD |
PMID:15761015 PMID:20458559 PMID:20707922 |
|
NCBI chr15:82,472,081...82,487,267
Ensembl chr15:82,472,065...82,487,262
|
|
| G
|
Klf9
|
KLF transcription factor 9
|
multiple interactions decreases expression
|
ISO
|
[Tretinoin co-treated with Arsenic Trioxide] results in increased expression of KLF9 mRNA; allicin inhibits the reaction [Arsenic Trioxide results in decreased expression of KLF9 protein] Arsenic Trioxide results in decreased expression of KLF9 mRNA; Arsenic Trioxide results in decreased expression of KLF9 protein
|
CTD |
PMID:15894607 PMID:19128835 PMID:27561292 |
|
NCBI chr 1:230,126,646...230,151,641
Ensembl chr 1:230,126,646...230,151,641
|
|
| G
|
Klhdc1
|
kelch domain containing 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of KLHDC1 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 6:93,406,226...93,501,475
Ensembl chr 6:93,448,758...93,501,702
|
|
| G
|
Klhdc8a
|
kelch domain containing 8A
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of KLHDC8A mRNA
|
CTD |
PMID:21461292 |
|
NCBI chr13:46,287,011...46,296,429
Ensembl chr13:46,288,344...46,296,429
|
|
| G
|
Klhdc9
|
kelch domain containing 9
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of KLHDC9 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr13:86,323,004...86,326,237
Ensembl chr13:86,323,004...86,325,653
|
|
| G
|
Klhl14
|
kelch-like family member 14
|
decreases expression multiple interactions
|
ISO
|
Arsenic Trioxide results in decreased expression of KLHL14 mRNA Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to KLHL14 protein]
|
CTD |
PMID:26598702 PMID:26705709 |
|
NCBI chr18:13,079,159...13,192,728
Ensembl chr18:13,079,159...13,193,557
|
|
| G
|
Klhl21
|
kelch-like family member 21
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of KLHL21 mRNA
|
CTD |
PMID:27829220 |
|
NCBI chr 5:167,797,621...167,806,276
Ensembl chr 5:167,797,591...167,806,276
|
|
| G
|
Klhl24
|
kelch-like family member 24
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of KLHL24 mRNA
|
CTD |
PMID:20458559 PMID:24356939 PMID:26705709 |
|
NCBI chr11:94,348,024...94,382,085
Ensembl chr11:94,351,157...94,382,050
|
|
| G
|
Klhl3
|
kelch-like family member 3
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of KLHL3 mRNA
|
CTD |
PMID:35676786 |
|
NCBI chr17:6,528,114...6,651,338
Ensembl chr17:6,528,487...6,651,338
|
|
| G
|
Klhl32
|
kelch-like family member 32
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to KLHL32 protein]
|
CTD |
PMID:26598702 |
|
NCBI chr 5:43,117,861...43,365,080
Ensembl chr 5:43,122,167...43,365,042
|
|
| G
|
Klhl42
|
kelch-like family, member 42
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of KLHL42 mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr 4:181,730,343...181,760,899
Ensembl chr 4:181,735,244...181,757,013
|
|
| G
|
Klhl6
|
kelch-like family member 6
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of KLHL6 mRNA
|
CTD |
PMID:27829220 |
|
NCBI chr11:94,475,262...94,514,653
Ensembl chr11:94,475,262...94,514,623
|
|
| G
|
Klk1c10
|
kallikrein 1-related peptidase C10
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [Metribolone promotes the reaction [AR protein binds to KLK3 promoter]]; Arsenic Trioxide inhibits the reaction [Metribolone promotes the reaction [NCOA2 protein binds to KLK3 promoter]]
|
CTD |
PMID:19131511 |
|
NCBI chr 1:103,539,527...103,543,586
Ensembl chr 1:103,539,527...103,543,586
|
|
| G
|
Klkb1
|
kallikrein B1
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of KLKB1 mRNA
|
CTD |
PMID:29633893 |
|
NCBI chr16:53,690,180...53,714,570
Ensembl chr16:53,691,220...53,716,339
|
|
| G
|
Klrk1
|
killer cell lectin like receptor K1
|
increases response to substance
|
ISO
|
KLRK1 protein results in increased susceptibility to Arsenic Trioxide
|
CTD |
PMID:18463537 |
|
NCBI chr 4:164,767,377...164,778,453
Ensembl chr 4:164,767,946...164,778,382
|
|
| G
|
Kmt2a
|
lysine methyltransferase 2A
|
multiple interactions decreases expression
|
ISO
|
[Arsenic Trioxide co-treated with Bortezomib] results in decreased expression of KMT2A mRNA Arsenic Trioxide results in decreased expression of KMT2A mRNA
|
CTD |
PMID:25913414 PMID:39716349 |
|
NCBI chr 8:54,013,547...54,089,219
Ensembl chr 8:54,013,547...54,089,317
|
|
| G
|
Kmt2c
|
lysine methyltransferase 2C
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of KMT2C mRNA
|
CTD |
PMID:22521957 |
|
NCBI chr 4:10,353,698...10,755,965
Ensembl chr 4:10,353,735...10,568,620
|
|
| G
|
Kpna2
|
karyopherin subunit alpha 2
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [GATA3 protein binds to KPNA2 protein]
|
CTD |
PMID:19080345 |
|
NCBI chr10:92,433,678...92,445,841
Ensembl chr10:92,433,679...92,445,937
|
|
| G
|
Krt13
|
keratin 13
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of KRT13 protein
|
CTD |
PMID:25419056 |
|
NCBI chr10:85,552,287...85,556,499
Ensembl chr10:85,552,287...85,556,499
|
|
| G
|
Krt14
|
keratin 14
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of KRT14 protein
|
CTD |
PMID:25419056 |
|
NCBI chr10:85,638,182...85,642,450
|
|
| G
|
Krt18
|
keratin 18
|
decreases response to substance increases expression
|
ISO
|
KRT18 protein results in decreased susceptibility to Arsenic Trioxide Arsenic Trioxide results in increased expression of KRT18 mRNA
|
CTD |
PMID:15073043 PMID:20707922 |
|
NCBI chr 7:135,036,168...135,039,844
Ensembl chr 7:135,035,982...135,039,848 Ensembl chr10:135,035,982...135,039,848
|
|
| G
|
Krt19
|
keratin 19
|
decreases expression decreases response to substance
|
ISO
|
Arsenic Trioxide results in decreased expression of KRT19 mRNA; Arsenic Trioxide results in decreased expression of KRT19 protein KRT19 protein results in decreased susceptibility to Arsenic Trioxide
|
CTD |
PMID:20707922 PMID:25419056 PMID:26705709 PMID:33634982 |
|
NCBI chr10:85,576,235...85,580,952
Ensembl chr10:85,576,235...85,580,952
|
|
| G
|
Krt27
|
keratin 27
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of KRT27 protein
|
CTD |
PMID:25419056 |
|
NCBI chr10:84,794,848...84,800,131
Ensembl chr10:84,794,684...84,800,131
|
|
| G
|
Krt7
|
keratin 7
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of KRT7 protein
|
CTD |
PMID:25419056 |
|
NCBI chr 7:134,407,626...134,423,787
Ensembl chr 7:134,407,584...134,423,786
|
|
| G
|
Krt71
|
keratin 71
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of KRT71 protein
|
CTD |
PMID:25419056 |
|
NCBI chr 7:134,752,240...134,778,765
Ensembl chr 7:134,752,248...134,761,033
|
|
| G
|
Krt8
|
keratin 8
|
decreases response to substance decreases expression increases expression
|
ISO
|
KRT8 protein results in decreased susceptibility to Arsenic Trioxide Arsenic Trioxide results in decreased expression of KRT8 protein Arsenic Trioxide results in increased expression of KRT8 protein
|
CTD |
PMID:20707922 PMID:25419056 PMID:33634982 |
|
NCBI chr 7:135,002,886...135,010,339
Ensembl chr 7:135,002,894...135,010,403
|
|
| G
|
Krt85
|
keratin 85
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of KRT85 protein
|
CTD |
PMID:25419056 |
|
NCBI chr 7:134,508,913...134,515,786
Ensembl chr 7:134,508,913...134,515,786
|
|
| G
|
Ktn1
|
kinectin 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of KTN1 protein
|
CTD |
PMID:25419056 |
|
NCBI chr15:23,392,570...23,485,061
Ensembl chr15:23,394,315...23,482,263
|
|
| G
|
Kynu
|
kynureninase
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of KYNU mRNA
|
CTD |
PMID:15761015 PMID:36801614 |
|
NCBI chr 3:48,188,286...48,338,996
Ensembl chr 3:48,188,182...48,339,014
|
|
| G
|
Lama3
|
laminin subunit alpha 3
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of LAMA3 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr18:3,797,898...4,033,021
Ensembl chr18:3,797,939...4,026,449
|
|
| G
|
Lamb3
|
laminin subunit beta 3
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of LAMB3 mRNA
|
CTD |
PMID:29633893 |
|
NCBI chr13:107,362,514...107,404,081
Ensembl chr13:107,322,526...107,404,081
|
|
| G
|
Lamc1
|
laminin subunit gamma 1
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of LAMC1 mRNA
|
CTD |
PMID:12852829 |
|
NCBI chr13:67,924,872...68,051,986
Ensembl chr13:67,924,872...68,051,986
|
|
| G
|
Lamc2
|
laminin subunit gamma 2
|
decreases response to substance
|
ISO
|
LAMC2 protein results in decreased susceptibility to Arsenic Trioxide
|
CTD |
PMID:20707922 |
|
NCBI chr13:67,835,199...67,894,694
Ensembl chr13:67,835,199...67,895,102
|
|
| G
|
Lamp1
|
lysosomal-associated membrane protein 1
|
multiple interactions increases expression affects expression
|
ISO
|
3-methyladenine inhibits the reaction [Arsenic Trioxide results in increased expression of LAMP1 mRNA]; 3-methyladenine inhibits the reaction [Arsenic Trioxide results in increased expression of LAMP1 protein]; Acetylcysteine affects the reaction [Arsenic Trioxide results in increased expression of LAMP1 mRNA]; Acetylcysteine affects the reaction [Arsenic Trioxide results in increased expression of LAMP1 protein]; Taurine inhibits the reaction [Arsenic Trioxide results in increased expression of LAMP1 protein]; TFEB protein affects the reaction [Arsenic Trioxide results in increased expression of LAMP1 protein] Arsenic Trioxide results in increased expression of LAMP1 mRNA; Arsenic Trioxide results in increased expression of LAMP1 protein Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased expression of LAMP1 mRNA]; TFEB protein affects the reaction [Arsenic Trioxide results in increased expression of LAMP1 mRNA]; TFEB protein affects the reaction [Arsenic Trioxide results in increased expression of LAMP1 protein] Arsenic Trioxide affects the expression of LAMP1 protein
|
CTD |
PMID:29307831 PMID:30237538 PMID:33462182 |
|
NCBI chr16:83,058,131...83,082,843
Ensembl chr16:83,058,385...83,075,159
|
|
| G
|
Lamp5
|
lysosomal-associated membrane protein family, member 5
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of LAMP5 mRNA
|
CTD |
PMID:26705709 |
|
NCBI chr 3:143,825,197...143,837,699
Ensembl chr 3:143,819,281...143,837,678
|
|
| G
|
Lamtor5
|
late endosomal/lysosomal adaptor, MAPK and MTOR activator 5
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of LAMTOR5 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 2:197,588,242...197,593,598
Ensembl chr 2:197,588,242...197,593,598
|
|
| G
|
Lap3
|
leucine aminopeptidase 3
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of LAP3 protein
|
CTD |
PMID:19364129 |
|
NCBI chr14:69,820,907...69,839,891
Ensembl chr14:69,820,908...69,839,891
|
|
| G
|
Laptm5
|
lysosomal protein transmembrane 5
|
increases expression multiple interactions
|
ISO
|
Arsenic Trioxide results in increased expression of LAPTM5 mRNA [Tretinoin co-treated with Arsenic Trioxide] results in increased expression of LAPTM5 mRNA
|
CTD |
PMID:15894607 PMID:20458559 |
|
NCBI chr 5:148,371,880...148,393,927
Ensembl chr 5:148,339,435...148,393,927
|
|
| G
|
Lasp1
|
LIM and SH3 protein 1
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to LASP1 protein]
|
CTD |
PMID:26598702 |
|
NCBI chr10:83,290,820...83,331,989
Ensembl chr10:83,290,865...83,331,988
|
|
| G
|
Lat
|
linker for activation of T cells
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of LAT mRNA
|
CTD |
PMID:15761015 |
|
NCBI chr 1:190,367,111...190,372,515
Ensembl chr 1:190,367,109...190,372,153
|
|
| G
|
Lat2
|
linker for activation of T cells family, member 2
|
decreases response to substance decreases expression
|
ISO
|
LAT2 protein results in decreased susceptibility to Arsenic Trioxide Arsenic Trioxide results in decreased expression of LAT2 mRNA; Arsenic Trioxide results in decreased expression of LAT2 protein
|
CTD |
PMID:19128835 PMID:23001822 PMID:32587277 |
|
NCBI chr12:27,740,647...27,754,760
Ensembl chr12:27,740,654...27,755,843
|
|
| G
|
Lats2
|
large tumor suppressor kinase 2
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of LATS2 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr15:35,940,632...35,992,225
Ensembl chr15:35,940,632...35,980,842
|
|
| G
|
Lbp
|
lipopolysaccharide binding protein
|
multiple interactions
|
ISO
|
[Arsenic Trioxide results in increased abundance of arsenite] which results in increased expression of LBP protein
|
CTD |
PMID:36791901 |
|
NCBI chr 3:167,373,786...167,400,941
Ensembl chr 3:167,373,924...167,401,518
|
|
| G
|
Lcat
|
lecithin cholesterol acyltransferase
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of LCAT mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr19:50,744,598...50,748,064
Ensembl chr19:50,744,601...50,748,081
|
|
| G
|
Lcn1
|
lipocalin 1
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of LCN1 mRNA
|
CTD |
PMID:25258189 |
|
NCBI chr 3:29,930,943...29,935,418
|
|
| G
|
Lcn2
|
lipocalin 2
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of LCN2 mRNA
|
CTD |
PMID:19763917 |
|
NCBI chr 3:36,078,432...36,081,851
Ensembl chr 3:36,078,436...36,081,842
|
|
| G
|
Lcorl
|
ligand dependent nuclear receptor corepressor-like
|
multiple interactions decreases expression
|
ISO
|
Metformin inhibits the reaction [Arsenic Trioxide results in decreased expression of LCORL mRNA]
|
CTD |
PMID:29095437 |
|
NCBI chr14:69,482,919...69,620,269
Ensembl chr14:69,518,837...69,587,177
|
|
| G
|
Lcp1
|
lymphocyte cytosolic protein 1
|
increases expression decreases expression
|
ISO
|
Arsenic Trioxide results in increased expression of LCP1 mRNA Arsenic Trioxide results in decreased expression of LCP1 protein
|
CTD |
PMID:22521957 PMID:25419056 |
|
NCBI chr15:56,846,375...56,954,090
Ensembl chr15:56,847,433...56,954,092
|
|
| G
|
Ldb2
|
LIM domain binding 2
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of LDB2 mRNA
|
CTD |
PMID:26705709 |
|
NCBI chr14:70,489,243...70,810,573
Ensembl chr14:70,489,620...70,810,574
|
|
| G
|
Ldb3
|
LIM domain binding 3
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of LDB3 mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr16:9,862,161...9,926,338
Ensembl chr16:9,862,161...9,926,985
|
|
| G
|
Ldha
|
lactate dehydrogenase A
|
increases expression decreases expression multiple interactions
|
ISO EXP
|
Arsenic Trioxide results in increased expression of LDHA mRNA Arsenic Trioxide results in decreased expression of LDHA mRNA; Arsenic Trioxide results in decreased expression of LDHA protein [Ascorbic Acid co-treated with Arsenic Trioxide] results in decreased expression of LDHA protein; Arsenic Trioxide promotes the reaction [Ascorbic Acid results in decreased expression of LDHA mRNA]; Arsenic Trioxide promotes the reaction [Ascorbic Acid results in decreased expression of LDHA protein]; Ascorbic Acid promotes the reaction [Arsenic Trioxide results in decreased expression of LDHA mRNA]; Ascorbic Acid promotes the reaction [Arsenic Trioxide results in decreased expression of LDHA protein] Diosgenin inhibits the reaction [Arsenic Trioxide results in increased expression of LDHA protein]
|
CTD |
PMID:20458559 PMID:38160894 PMID:39059093 |
|
NCBI chr 1:106,508,092...106,517,512
Ensembl chr 1:106,502,182...106,517,521
|
|
| G
|
Ldhb
|
lactate dehydrogenase B
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of LDHB protein
|
CTD |
PMID:19364129 |
|
NCBI chr 4:177,159,389...177,177,408
Ensembl chr 4:177,159,392...177,177,408
|
|
| G
|
Ldlrad1
|
low density lipoprotein receptor class A domain containing 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of LDLRAD1 mRNA
|
CTD |
PMID:25258189 |
|
NCBI chr 5:127,212,581...127,229,753
Ensembl chr 5:127,220,764...127,229,725
|
|
| G
|
Ldlrad4
|
low density lipoprotein receptor class A domain containing 4
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of LDLRAD4 mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr18:63,789,089...64,118,166
Ensembl chr18:63,790,440...64,113,064
|
|
| G
|
Ldoc1
|
LDOC1, regulator of NFKB signaling
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of LDOC1 mRNA
|
CTD |
PMID:25258189 |
|
NCBI chr X:144,837,879...145,110,607
Ensembl chr X:144,837,865...145,111,017
|
|
| G
|
Lemd3
|
LEM domain containing 3
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of LEMD3 mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr 7:58,300,556...58,389,485
Ensembl chr 7:58,316,851...58,384,707
|
|
| G
|
Lep
|
leptin
|
multiple interactions
|
ISO
|
Arsenic Trioxide results in decreased expression of and results in decreased secretion of LEP protein; Fenofibrate inhibits the reaction [Arsenic Trioxide results in decreased expression of and results in decreased secretion of LEP protein]
|
CTD |
PMID:32929351 |
|
NCBI chr 4:58,626,529...58,640,663
Ensembl chr 4:58,626,523...58,640,661
|
|
| G
|
Lfng
|
LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
|
decreases expression increases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of LFNG mRNA Arsenic Trioxide results in increased expression of LFNG mRNA
|
CTD |
PMID:20458559 PMID:35676786 |
|
NCBI chr12:19,144,474...19,152,951
Ensembl chr12:19,124,662...19,152,918
|
|
| G
|
Lgals1
|
galectin 1
|
decreases expression decreases secretion increases response to substance
|
ISO
|
Arsenic Trioxide results in decreased expression of LGALS1 protein LGALS1 protein results in decreased secretion of Arsenic Trioxide Arsenic Trioxide results in decreased expression of LGALS1 mRNA; Arsenic Trioxide results in decreased expression of LGALS1 protein LGALS1 protein results in increased susceptibility to Arsenic Trioxide
|
CTD |
PMID:20458559 PMID:21596116 |
|
NCBI chr 7:112,365,695...112,368,801
Ensembl chr 7:112,361,850...112,368,800
|
|
| G
|
Lgals2
|
galectin 2
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of LGALS2 mRNA
|
CTD |
PMID:19128835 |
|
NCBI chr 7:112,283,630...112,290,228
Ensembl chr 7:112,282,822...112,285,392
|
|
| G
|
Lgals3
|
galectin 3
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of LGALS3 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr15:23,099,795...23,111,731
Ensembl chr15:23,086,841...23,111,737
|
|
| G
|
Lgals3bp
|
galectin 3 binding protein
|
multiple interactions increases expression
|
ISO
|
[Tretinoin co-treated with Arsenic Trioxide] results in increased expression of LGALS3BP mRNA Arsenic Trioxide results in increased expression of LGALS3BP protein
|
CTD |
PMID:15894607 PMID:25419056 |
|
NCBI chr10:104,118,510...104,127,848
Ensembl chr10:104,118,510...104,127,848
|
|
| G
|
Lgals8
|
galectin 8
|
affects expression increases expression
|
ISO
|
Arsenic Trioxide affects the expression of LGALS8 mRNA Arsenic Trioxide results in increased expression of LGALS8 mRNA
|
CTD |
PMID:20458559 PMID:25873331 |
|
NCBI chr17:62,716,368...62,744,272
Ensembl chr17:62,719,828...62,744,482
|
|
| G
|
Lgals9
|
galectin 9
|
increases expression multiple interactions
|
ISO
|
Arsenic Trioxide results in increased expression of LGALS9 mRNA [Tretinoin co-treated with Arsenic Trioxide] results in increased expression of LGALS9 mRNA
|
CTD |
PMID:15761015 PMID:15894607 |
|
NCBI chr10:64,405,044...64,428,249
Ensembl chr10:64,405,044...64,428,070
|
|
| G
|
Lgalsl
|
galectin-like
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to LGALSL protein]
|
CTD |
PMID:26598702 |
|
NCBI chr14:99,198,340...99,205,846
Ensembl chr14:99,198,339...99,206,487
|
|
| G
|
Lgi1
|
leucine-rich, glioma inactivated 1
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of LGI1 mRNA
|
CTD |
PMID:26705709 |
|
NCBI chr 1:245,455,691...245,497,036
Ensembl chr 1:245,455,599...245,499,095
|
|
| G
|
Lgi3
|
leucine-rich repeat LGI family, member 3
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of LGI3 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr15:52,015,317...52,022,445
Ensembl chr15:52,015,230...52,022,443
|
|
| G
|
Lgmn
|
legumain
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of LGMN mRNA
|
CTD |
PMID:15725085 |
|
NCBI chr 6:127,308,913...127,347,355
Ensembl chr 6:127,308,913...127,347,328
|
|
| G
|
Lgr4
|
leucine-rich repeat-containing G protein-coupled receptor 4
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of LGR4 mRNA
|
CTD |
PMID:27829220 |
|
NCBI chr 3:116,901,968...117,004,584
Ensembl chr 3:116,901,968...117,004,153
|
|
| G
|
Lgr5
|
leucine rich repeat containing G protein coupled receptor 5
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of LGR5 mRNA
|
CTD |
PMID:26705709 |
|
NCBI chr 7:52,973,151...53,107,964
Ensembl chr 7:52,974,332...53,108,163
|
|
| G
|
Lhb
|
luteinizing hormone subunit beta
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of LHB protein
|
CTD |
PMID:18630931 |
|
NCBI chr 1:105,037,457...105,038,446
Ensembl chr 1:105,037,457...105,038,445
|
|
| G
|
Lhfpl2
|
LHFPL tetraspan subfamily member 2
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of LHFPL2 mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr 2:27,016,404...27,169,830
Ensembl chr 2:27,016,700...27,162,859
|
|
| G
|
Lhfpl5
|
LHFPL tetraspan subfamily member 5
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of LHFPL5 mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr20:6,634,058...6,644,264
Ensembl chr20:6,633,979...6,644,657
|
|
| G
|
Lhfpl6
|
LHFPL tetraspan subfamily member 6
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of LHFPL6 mRNA
|
CTD |
PMID:15070760 PMID:15761015 |
|
NCBI chr 2:139,276,810...139,474,740
Ensembl chr 2:139,276,789...139,474,737
|
|
| G
|
Lhx6
|
LIM homeobox 6
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of LHX6 mRNA
|
CTD |
PMID:15761015 |
|
NCBI chr 3:39,829,846...39,853,681
Ensembl chr 3:39,830,990...39,853,559
|
|
| G
|
Lif
|
LIF, interleukin 6 family cytokine
|
increases expression decreases expression
|
ISO
|
Arsenic Trioxide results in increased expression of LIF mRNA Arsenic Trioxide results in decreased expression of LIF mRNA; Arsenic Trioxide results in decreased expression of LIF protein
|
CTD |
PMID:20458559 PMID:26705709 PMID:33634982 |
|
NCBI chr14:83,354,602...83,364,053
Ensembl chr14:83,358,164...83,364,053
|
|
| G
|
Limd1
|
LIM domain containing 1
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to LIMD1 protein]
|
CTD |
PMID:26598702 |
|
NCBI chr 8:131,998,262...132,045,924
Ensembl chr 8:131,999,770...132,045,922
|
|
| G
|
Limd2
|
LIM domain containing 2
|
increases response to substance
|
ISO
|
LIMD2 protein results in increased susceptibility to Arsenic Trioxide
|
CTD |
PMID:20707922 |
|
NCBI chr10:91,590,079...91,592,747
Ensembl chr10:91,590,082...91,592,439
|
|
| G
|
Lin7c
|
lin-7 homolog C, crumbs cell polarity complex component
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of LIN7C mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 3:116,859,425...116,872,363
Ensembl chr 3:116,860,282...116,872,363
|
|
| G
|
Litaf
|
lipopolysaccharide-induced TNF factor
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to LITAF protein]
|
CTD |
PMID:26598702 |
|
NCBI chr10:5,163,258...5,199,930
Ensembl chr10:5,163,242...5,199,930
|
|
| G
|
Lix1l
|
limb and CNS expressed 1 like
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of LIX1L mRNA
|
CTD |
PMID:22521957 |
|
NCBI chr 2:186,824,864...186,850,761
Ensembl chr 2:186,824,884...186,850,759
|
|
| G
|
Llgl2
|
LLGL scribble cell polarity complex component 2
|
decreases response to substance multiple interactions
|
ISO
|
LLGL2 protein results in decreased susceptibility to Arsenic Trioxide [Arsenic Trioxide co-treated with apatinib] results in decreased expression of LLGL2 mRNA
|
CTD |
PMID:20707922 PMID:39223679 |
|
NCBI chr10:101,549,911...101,585,466
Ensembl chr10:101,549,862...101,585,464
|
|
| G
|
Lmf1
|
lipase maturation factor 1
|
decreases expression increases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of LMF1 mRNA Arsenic Trioxide results in increased expression of LMF1 mRNA
|
CTD |
PMID:26705709 PMID:35676786 |
|
NCBI chr10:15,094,432...15,188,665
Ensembl chr10:15,098,138...15,188,664
|
|
| G
|
Lmna
|
lamin A/C
|
multiple interactions increases expression
|
ISO
|
Metformin inhibits the reaction [Arsenic Trioxide results in increased expression of LMNA mRNA]
|
CTD |
PMID:29095437 |
|
NCBI chr 2:176,237,564...176,265,301
Ensembl chr 2:176,237,564...176,288,072
|
|
| G
|
Lmo2
|
LIM domain only 2
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of LMO2 mRNA
|
CTD |
PMID:19128835 |
|
NCBI chr 3:110,810,162...110,832,895
Ensembl chr 3:110,809,912...110,833,075
|
|
| G
|
Lmod1
|
leiomodin 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of LMOD1 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr13:49,305,693...49,347,970
Ensembl chr13:49,305,830...49,348,116
|
|
| G
|
Lmx1a
|
LIM homeobox transcription factor 1 alpha
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of LMX1A mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr13:82,367,493...82,511,157
Ensembl chr13:82,367,933...82,511,154
|
|
| G
|
Lnpep
|
leucyl and cystinyl aminopeptidase
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of LNPEP mRNA
|
CTD |
PMID:35676786 |
|
NCBI chr 1:66,931,712...67,027,610
Ensembl chr 1:66,931,712...67,027,610
|
|
| G
|
Lnpk
|
lunapark, ER junction formation factor
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of LNPK mRNA
|
CTD |
PMID:35676786 |
|
NCBI chr 3:79,826,318...79,894,514
Ensembl chr 3:79,832,753...79,894,403
|
|
| G
|
Loxl4
|
lysyl oxidase-like 4
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of LOXL4 mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr 1:251,345,445...251,365,640
Ensembl chr 1:251,347,238...251,365,577
|
|
| G
|
Lpar2
|
lysophosphatidic acid receptor 2
|
decreases response to substance
|
ISO
|
LPAR2 protein results in decreased susceptibility to Arsenic Trioxide
|
CTD |
PMID:20707922 |
|
NCBI chr16:19,625,974...19,633,905
Ensembl chr16:19,625,983...19,633,905
|
|
| G
|
Lpar4
|
lysophosphatidic acid receptor 4
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to LPAR4 protein]
|
CTD |
PMID:26598702 |
|
NCBI chr X:76,106,319...76,119,807
Ensembl chr X:76,106,071...76,119,808
|
|
| G
|
Lpcat1
|
lysophosphatidylcholine acyltransferase 1
|
multiple interactions decreases expression
|
ISO
|
[Tretinoin co-treated with Arsenic Trioxide] results in increased expression of LPCAT1 mRNA Arsenic Trioxide results in decreased expression of LPCAT1 mRNA
|
CTD |
PMID:15894607 PMID:39716349 |
|
NCBI chr 1:31,594,621...31,644,946
Ensembl chr 1:31,594,622...31,644,946
|
|
| G
|
Lpcat4
|
lysophosphatidylcholine acyltransferase 4
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of LPCAT4 mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr 3:119,499,128...119,507,275
Ensembl chr 3:119,499,128...119,507,362
|
|
| G
|
Lpin3
|
lipin 3
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of LPIN3 mRNA
|
CTD |
PMID:35676786 PMID:39716349 |
|
NCBI chr 3:169,953,479...169,978,034
Ensembl chr 3:169,960,522...169,978,031
|
|
| G
|
Lpl
|
lipoprotein lipase
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of LPL mRNA
|
CTD |
PMID:19128835 PMID:26705709 |
|
NCBI chr16:25,596,205...25,621,928
Ensembl chr16:25,596,211...25,622,107
|
|
| G
|
Lrp1
|
LDL receptor related protein 1
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of LRP1 mRNA
|
CTD |
PMID:22521957 |
|
NCBI chr 7:65,265,639...65,346,196
Ensembl chr 7:65,265,639...65,346,196
|
|
| G
|
Lrp4
|
LDL receptor related protein 4
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of LRP4 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 3:97,885,373...97,939,366
Ensembl chr 3:97,885,400...97,939,370
|
|
| G
|
Lrpap1
|
LDL receptor related protein associated protein 1
|
multiple interactions
|
ISO
|
[Tretinoin co-treated with Arsenic Trioxide] results in increased expression of LRPAP1 mRNA
|
CTD |
PMID:15894607 |
|
NCBI chr14:79,876,002...79,888,011
Ensembl chr14:79,875,708...79,890,034
|
|
| G
|
Lrrc31
|
leucine rich repeat containing 31
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of LRRC31 mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr 2:114,624,177...114,654,909
Ensembl chr 2:114,631,136...114,652,269
|
|
| G
|
Lrrc3b
|
leucine rich repeat containing 3B
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of LRRC3B mRNA
|
CTD |
PMID:26705709 |
|
NCBI chr15:12,404,309...12,481,618
Ensembl chr15:12,336,369...12,481,866
|
|
| G
|
Lrrc59
|
leucine rich repeat containing 59
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of LRRC59 protein
|
CTD |
PMID:25419056 |
|
NCBI chr10:80,069,162...80,083,820
Ensembl chr10:80,069,120...80,084,079
|
|
| G
|
Lrrc7
|
leucine rich repeat containing 7
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of LRRC7 mRNA
|
CTD |
PMID:26705709 |
|
NCBI chr 2:249,792,441...250,294,267
Ensembl chr 2:249,805,448...250,293,718
|
|
| G
|
Lrrc8b
|
leucine rich repeat containing 8 VRAC subunit B
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of LRRC8B mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr14:4,655,273...4,721,648
Ensembl chr14:4,655,273...4,721,076
|
|
| G
|
Lrrfip1
|
LRR binding FLII interacting protein 1
|
affects expression
|
ISO
|
Arsenic Trioxide affects the expression of LRRFIP1 mRNA
|
CTD |
PMID:25258189 |
|
NCBI chr 9:99,039,590...99,167,805
Ensembl chr 9:99,039,614...99,167,779
|
|
| G
|
Lrrk1
|
leucine-rich repeat kinase 1
|
multiple interactions increases expression
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to LRRK1 protein] Arsenic Trioxide results in increased expression of LRRK1 mRNA
|
CTD |
PMID:20458559 PMID:26598702 |
|
NCBI chr 1:129,254,815...129,390,217
Ensembl chr 1:129,254,515...129,389,941
|
|
| G
|
Lrrn4
|
leucine rich repeat neuronal 4
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of LRRN4 mRNA
|
CTD |
PMID:35676786 |
|
NCBI chr 3:140,592,303...140,603,986
Ensembl chr 3:140,592,076...140,605,574
|
|
| G
|
Lsamp
|
limbic system-associated membrane protein
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of LSAMP mRNA
|
CTD |
PMID:26705709 |
|
NCBI chr11:72,053,285...74,223,019
Ensembl chr11:72,053,285...72,702,134
|
|
| G
|
Lsm11
|
LSM11, U7 small nuclear RNA associated
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of LSM11 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr10:30,869,168...30,887,275
Ensembl chr10:30,872,054...30,887,269
|
|
| G
|
Lsm12
|
LSM12 homolog
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to LSM12 protein]
|
CTD |
PMID:26598702 |
|
NCBI chr10:87,618,518...87,640,556
Ensembl chr10:87,618,518...87,640,556
|
|
| G
|
Lsm2
|
LSM2 homolog, U6 small nuclear RNA and mRNA degradation associated
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of LSM2 mRNA
|
CTD |
PMID:35676786 |
|
NCBI chr20:3,848,120...3,853,298
Ensembl chr20:3,848,119...3,851,891
|
|
| G
|
Lsp1
|
lymphocyte-specific protein 1
|
multiple interactions increases expression
|
ISO
|
[Arsenic Trioxide co-treated with Tretinoin] results in increased expression of LSP1 mRNA; [Tretinoin co-treated with Arsenic Trioxide] results in increased expression of LSP1 mRNA Arsenic Trioxide results in increased expression of LSP1 mRNA
|
CTD |
PMID:15761015 PMID:15894607 PMID:38179723 |
|
NCBI chr 1:207,044,157...207,077,891
Ensembl chr 1:207,044,159...207,077,893
|
|
| G
|
Lsr
|
lipolysis stimulated lipoprotein receptor
|
decreases expression decreases response to substance
|
ISO
|
Arsenic Trioxide results in decreased expression of LSR mRNA LSR protein results in decreased susceptibility to Arsenic Trioxide
|
CTD |
PMID:20707922 PMID:22521957 |
|
NCBI chr 1:95,313,830...95,329,471
Ensembl chr 1:95,313,033...95,329,354
|
|
| G
|
Lta
|
lymphotoxin alpha
|
multiple interactions increases expression
|
ISO EXP
|
[Arsenic Trioxide co-treated with Curcumin] results in increased expression of LTA protein Arsenic Trioxide results in increased expression of LTA mRNA
|
CTD |
PMID:19730151 PMID:20458559 PMID:27430728 |
|
NCBI chr20:3,622,291...3,625,852
Ensembl chr20:3,623,527...3,625,533
|
|
| G
|
Lta4h
|
leukotriene A4 hydrolase
|
decreases response to substance
|
ISO
|
LTA4H protein results in decreased susceptibility to Arsenic Trioxide
|
CTD |
PMID:20707922 |
|
NCBI chr 7:29,856,846...29,888,642
Ensembl chr 7:29,856,802...29,888,641
|
|
| G
|
Ltb
|
lymphotoxin beta
|
multiple interactions increases expression
|
ISO
|
[sanguinarine co-treated with Arsenic Trioxide] results in increased expression of LTB mRNA Arsenic Trioxide results in increased expression of LTB mRNA
|
CTD |
PMID:24345465 |
|
NCBI chr20:3,632,209...3,634,054
Ensembl chr20:3,632,210...3,634,054
|
|
| G
|
Ltbr
|
lymphotoxin beta receptor
|
increases expression
|
EXP
|
Arsenic Trioxide results in increased expression of LTBR mRNA
|
CTD |
PMID:19730151 |
|
NCBI chr 4:159,795,115...159,801,571
Ensembl chr 4:159,795,115...159,807,296
|
|
| G
|
Ltc4s
|
leukotriene C4 synthase
|
increases expression decreases expression
|
ISO
|
Arsenic Trioxide results in increased expression of LTC4S mRNA Arsenic Trioxide results in decreased expression of LTC4S mRNA
|
CTD |
PMID:15761015 PMID:20458559 |
|
NCBI chr10:35,060,002...35,066,466
Ensembl chr10:35,061,437...35,063,768
|
|
| G
|
Ly6e
|
lymphocyte antigen 6 family member E
|
multiple interactions
|
ISO
|
[Tretinoin co-treated with Arsenic Trioxide] results in increased expression of LY6E mRNA; Arsenic Trioxide inhibits the reaction [Tretinoin results in increased expression of LY6E protein]
|
CTD |
PMID:11133770 PMID:15894607 |
|
NCBI chr 7:108,815,970...108,820,444
Ensembl chr 7:108,816,887...108,820,443
|
|
| G
|
Ly96
|
lymphocyte antigen 96
|
multiple interactions increases expression
|
ISO
|
[Arsenic Trioxide co-treated with Bortezomib] results in increased expression of LY96 mRNA Arsenic Trioxide results in increased expression of LY96 mRNA
|
CTD |
PMID:25913414 PMID:26705709 PMID:27829220 |
|
NCBI chr 5:7,365,536...7,397,864
Ensembl chr 5:7,365,557...7,395,816
|
|
| G
|
Lypd6
|
Ly6/Plaur domain containing 6
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of LYPD6 mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr 3:54,896,618...55,041,928
Ensembl chr 3:54,896,575...55,041,929
|
|
| G
|
Lypd6b
|
Ly6/Plaur domain containing 6B
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of LYPD6B mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr 3:54,608,320...54,769,974
Ensembl chr 3:54,757,444...54,769,974
|
|
| G
|
Lypd8
|
Ly6/Plaur domain containing 8
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of LYPD8 mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr10:43,062,261...43,073,108
Ensembl chr10:43,065,186...43,073,105
|
|
| G
|
Lypla1
|
lysophospholipase 1
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of LYPLA1 protein
|
CTD |
PMID:19364129 |
|
NCBI chr 5:19,477,408...19,506,568
Ensembl chr 5:19,477,409...19,506,522
|
|
| G
|
Lypla2
|
lysophospholipase 2
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to LYPLA2 protein]
|
CTD |
PMID:26598702 |
|
NCBI chr 5:153,481,973...153,486,692
Ensembl chr 5:153,481,974...153,486,601
|
|
| G
|
Lyve1
|
lymphatic vessel endothelial hyaluronan receptor 1
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of LYVE1 mRNA; Arsenic Trioxide results in decreased expression of LYVE1 protein
|
CTD |
PMID:38275666 |
|
NCBI chr 1:174,393,387...174,410,977
|
|
| G
|
Lztfl1
|
leucine zipper transcription factor-like 1
|
increases response to substance
|
ISO
|
LZTFL1 protein results in increased susceptibility to Arsenic Trioxide
|
CTD |
PMID:20707922 |
|
NCBI chr 8:132,222,339...132,237,757
Ensembl chr 8:132,222,342...132,237,684
|
|
| G
|
Macf1
|
microtubule-actin crosslinking factor 1
|
decreases expression increases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of MACF1 protein Arsenic Trioxide results in increased expression of MACF1 mRNA
|
CTD |
PMID:15894607 PMID:39716349 |
|
NCBI chr 5:140,908,829...141,234,127
Ensembl chr 5:140,908,837...141,233,890
|
|
| G
|
Macrod2
|
mono-ADP ribosylhydrolase 2
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of MACROD2 mRNA
|
CTD |
PMID:35676786 |
|
NCBI chr 3:148,173,821...150,191,077
Ensembl chr 3:148,173,829...150,188,058
|
|
| G
|
Macroh2a2
|
macroH2A.2 histone
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of MACROH2A2 mRNA
|
CTD |
PMID:22521957 |
|
NCBI chr20:30,220,975...30,270,652
Ensembl chr20:30,221,011...30,270,652
|
|
| G
|
Mad1l1
|
mitotic arrest deficient 1 like 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of MAD1L1 mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr12:19,434,782...19,744,574
Ensembl chr12:19,434,746...19,744,567
|
|
| G
|
Mad2l1
|
mitotic arrest deficient 2 like 1
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of MAD2L1 mRNA
|
CTD |
PMID:27829220 |
|
NCBI chr 4:97,236,419...97,247,603
Ensembl chr 4:97,236,503...97,243,222
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Maff
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MAF bZIP transcription factor F
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increases expression
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ISO
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Arsenic Trioxide results in increased expression of MAFF mRNA; Arsenic Trioxide results in increased expression of MAFF protein
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CTD |
PMID:16487037 PMID:26705709 |
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NCBI chr 7:112,792,787...112,804,139
Ensembl chr 7:112,791,416...112,804,147
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| G
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Mafk
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MAF bZIP transcription factor K
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affects methylation
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ISO
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Arsenic Trioxide affects the methylation of MAFK promoter
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CTD |
PMID:26046465 |
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NCBI chr12:19,948,473...19,970,351
Ensembl chr12:19,948,476...19,959,192
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| G
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Magea13
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MAGE family member A13
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increases expression
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ISO
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Arsenic Trioxide results in increased expression of MAGEA12 mRNA
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CTD |
PMID:39716349 |
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NCBI chr X:142,106,603...142,112,462
Ensembl chr X:142,106,603...142,112,457
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| G
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Maged2
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MAGE family member D2
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increases expression
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ISO
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Arsenic Trioxide results in increased expression of MAGED2 mRNA
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CTD |
PMID:39716349 |
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NCBI chr X:23,160,928...23,364,994
Ensembl chr X:23,160,931...23,169,104
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| G
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Mak
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male germ cell-associated kinase
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decreases expression
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ISO
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Arsenic Trioxide results in decreased expression of MAK mRNA
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CTD |
PMID:21461292 |
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NCBI chr17:23,889,417...23,936,857
Ensembl chr17:23,889,516...23,936,855
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| G
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Mall
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mal, T-cell differentiation protein-like
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decreases response to substance
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ISO
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MALL protein results in decreased susceptibility to Arsenic Trioxide
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CTD |
PMID:20707922 |
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NCBI chr 3:135,381,180...135,404,136
Ensembl chr 3:135,377,410...135,404,066
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| G
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Mamdc2
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MAM domain containing 2
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decreases expression
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ISO
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Arsenic Trioxide results in decreased expression of MAMDC2 mRNA
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CTD |
PMID:26705709 |
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NCBI chr 1:230,290,482...230,443,014
Ensembl chr 1:230,290,499...230,442,711
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| G
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Maml1
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mastermind-like transcriptional coactivator 1
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increases expression
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ISO
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Arsenic Trioxide results in increased expression of MAML1 mRNA
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CTD |
PMID:20458559 |
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NCBI chr10:35,089,715...35,124,100
Ensembl chr10:35,089,715...35,124,100
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| G
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Man1a1
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mannosidase, alpha, class 1A, member 1
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increases expression
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ISO
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Arsenic Trioxide results in increased expression of MAN1A1 mRNA
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CTD |
PMID:15761015 |
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NCBI chr20:33,745,158...33,928,584
Ensembl chr20:33,745,165...33,928,584
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| G
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Man1a2
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mannosidase, alpha, class 1A, member 2
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increases expression
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ISO
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Arsenic Trioxide results in increased expression of MAN1A2 mRNA
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CTD |
PMID:20458559 |
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NCBI chr 2:190,636,134...190,784,975
Ensembl chr 2:190,615,094...190,784,975
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| G
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Man1c1
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mannosidase, alpha, class 1C, member 1
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decreases expression
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ISO
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Arsenic Trioxide results in decreased expression of MAN1C1 mRNA
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CTD |
PMID:26705709 |
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NCBI chr 5:152,057,839...152,197,737
Ensembl chr 5:152,057,967...152,197,138
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| G
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Manf
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mesencephalic astrocyte-derived neurotrophic factor
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decreases expression
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ISO
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Arsenic Trioxide results in decreased expression of MANF mRNA
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CTD |
PMID:20458559 |
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NCBI chr 8:116,427,053...116,430,259
Ensembl chr 8:116,427,048...116,429,910
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| G
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Maoa
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monoamine oxidase A
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increases expression
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ISO
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Arsenic Trioxide results in increased expression of MAOA mRNA
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CTD |
PMID:15761015 PMID:22521957 |
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NCBI chr X:8,615,239...8,681,372
Ensembl chr X:8,615,239...8,682,631
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| G
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Map1b
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microtubule-associated protein 1B
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increases expression
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ISO
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Arsenic Trioxide results in increased expression of MAP1B mRNA
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CTD |
PMID:20458559 |
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NCBI chr 2:32,551,423...32,644,471
Ensembl chr 2:32,551,423...32,657,094
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| G
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Map1lc3a
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microtubule-associated protein 1 light chain 3 alpha
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increases expression multiple interactions
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ISO EXP
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Arsenic Trioxide results in increased expression of MAP1LC3A protein Arsenic Trioxide results in increased expression of MAP1LC3A mRNA Riboflavin inhibits the reaction [Arsenic Trioxide results in increased expression of MAP1LC3A mRNA]
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CTD |
PMID:20200477 PMID:30032600 PMID:30225639 PMID:31846860 PMID:34062077 |
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NCBI chr 3:164,243,204...164,244,850
Ensembl chr 3:164,243,093...164,244,850
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| G
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Map1lc3b
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microtubule-associated protein 1 light chain 3 beta
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multiple interactions increases expression increases lipidation increases cleavage
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ISO EXP
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3-methyladenine inhibits the reaction [Arsenic Trioxide results in increased cleavage of MAP1LC3B protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased expression of MAP1LC3B mRNA]; Arsenic Trioxide inhibits the reaction [TRIM44 protein results in increased lipidation of MAP1LC3B protein]; Arsenic Trioxide promotes the reaction [bafilomycin A results in increased expression of MAP1LC3B protein modified form]; Arsenic Trioxide results in increased metabolism of and affects the localization of MAP1LC3B protein; Chloroquine promotes the reaction [Arsenic Trioxide results in increased expression of MAP1LC3B protein]; MK-886 inhibits the reaction [Arsenic Trioxide results in increased cleavage of MAP1LC3B protein]; Taurine inhibits the reaction [Arsenic Trioxide results in increased cleavage of MAP1LC3B protein]; Taurine inhibits the reaction [Arsenic Trioxide results in increased expression of MAP1LC3B protein]; TFEB protein affects the reaction [Arsenic Trioxide results in increased expression of MAP1LC3B mRNA]; TP73 protein affects the reaction [Arsenic Trioxide promotes the reaction [bafilomycin A results in increased expression of MAP1LC3B protein modified form]] Arsenic Trioxide results in increased expression of MAP1LC3B mRNA; Arsenic Trioxide results in increased expression of MAP1LC3B protein Arsenic Trioxide results in increased expression of MAP1LC3B mRNA; Arsenic Trioxide results in increased expression of MAP1LC3B protein; Arsenic Trioxide results in increased expression of MAP1LC3B protein modified form Arsenic Trioxide results in increased lipidation of MAP1LC3B protein [ferrostatin-1 co-treated with Arsenic Trioxide] results in increased lipidation of MAP1LC3B protein; dapagliflozin inhibits the reaction [Arsenic Trioxide results in increased expression of MAP1LC3B protein]; MAP1LC3B protein affects the reaction [Arsenic Trioxide results in decreased expression of SQSTM1 protein]; MAP1LC3B protein affects the reaction [Arsenic Trioxide results in increased lipidation of MAP1LC3B protein]
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CTD |
PMID:28978663 PMID:29111283 PMID:29307831 PMID:29743969 PMID:30032600 PMID:30225639 PMID:30237538 PMID:30338810 PMID:30677399 PMID:31846860 PMID:32112876 PMID:32284743 PMID:33462182 PMID:35195477 PMID:38070468 PMID:38684648 PMID:39152142 More...
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NCBI chr19:66,571,631...66,582,270
Ensembl chr19:66,574,407...66,584,358 Ensembl chr16:66,574,407...66,584,358
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| G
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Map2
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microtubule-associated protein 2
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decreases expression
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ISO
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Arsenic Trioxide results in decreased expression of MAP2 protein
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CTD |
PMID:15894607 |
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NCBI chr 9:75,173,038...75,431,606
Ensembl chr 9:75,288,262...75,428,459
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| G
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Map2k1
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mitogen activated protein kinase kinase 1
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decreases phosphorylation multiple interactions increases expression decreases activity
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ISO
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Arsenic Trioxide results in decreased phosphorylation of MAP2K1 protein 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Arsenic Trioxide promotes the reaction [Tretinoin results in increased phosphorylation of and results in increased activity of MAP2K1 protein]]; Arsenic Trioxide promotes the reaction [Tretinoin results in increased phosphorylation of and results in increased activity of MAP2K1 protein]; Arsenic Trioxide results in increased phosphorylation of and results in increased activity of MAP2K1 protein Arsenic Trioxide results in increased expression of MAP2K1 mRNA Arsenic Trioxide results in decreased activity of MAP2K1 protein
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CTD |
PMID:11304686 PMID:20592496 PMID:20615082 PMID:22521957 PMID:28454374 |
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NCBI chr 8:73,578,747...73,650,184
Ensembl chr 8:73,578,752...73,650,184
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| G
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Map2k2
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mitogen activated protein kinase kinase 2
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decreases activity multiple interactions increases expression
|
ISO
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Arsenic Trioxide results in decreased activity of MAP2K2 protein 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Arsenic Trioxide promotes the reaction [Tretinoin results in increased phosphorylation of and results in increased activity of MAP2K2 protein]]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of and results in increased activity of MAP2K2 protein]; Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to MAP2K2 protein]; Arsenic Trioxide promotes the reaction [Tretinoin results in increased phosphorylation of and results in increased activity of MAP2K2 protein]; Arsenic Trioxide results in increased phosphorylation of and results in increased activity of MAP2K2 protein Arsenic Trioxide results in increased expression of MAP2K2 protein
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CTD |
PMID:11304686 PMID:20615082 PMID:25419056 PMID:26598702 |
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NCBI chr 7:9,241,449...9,264,216
Ensembl chr 7:9,241,310...9,260,940
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| G
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Map2k3
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mitogen activated protein kinase kinase 3
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multiple interactions affects response to substance increases expression
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ISO
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MAP2K3 protein promotes the reaction [Arsenic Trioxide results in increased phosphorylation of and results in increased activity of MAPK14 protein] 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of and results in increased activity of MAP2K3 protein]; Arsenic Trioxide results in increased phosphorylation of and results in increased activity of MAP2K3 protein MAP2K3 protein affects the susceptibility to Arsenic Trioxide Arsenic Trioxide results in increased expression of MAP2K3 mRNA
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CTD |
PMID:16818652 PMID:20615082 PMID:29633893 |
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NCBI chr10:46,107,639...46,128,986
Ensembl chr10:46,106,548...46,129,004
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| G
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Map2k4
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mitogen activated protein kinase kinase 4
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multiple interactions increases response to substance
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ISO
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MAP2K4 gene mutant form inhibits the reaction [Arsenic Trioxide results in increased activity of MAPK8 protein]; MAP2K4 protein promotes the reaction [Arsenic Trioxide results in increased expression of HSPA6 mRNA]; MAP2K4 protein promotes the reaction [Arsenic Trioxide results in increased expression of HSPA6 protein]; MAP2K4 protein promotes the reaction [Arsenic Trioxide results in increased phosphorylation of HSF1 protein] MAP2K4 protein results in increased susceptibility to Arsenic Trioxide; MAP2K4 results in increased susceptibility to Arsenic Trioxide
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CTD |
PMID:14701702 PMID:15978632 PMID:16184197 PMID:18633430 |
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NCBI chr10:50,842,348...50,947,063
Ensembl chr10:50,844,034...50,947,185
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| G
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Map2k6
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mitogen-activated protein kinase kinase 6
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decreases expression affects response to substance multiple interactions
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ISO
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Arsenic Trioxide results in decreased expression of MAP2K6 mRNA MAP2K6 protein affects the susceptibility to Arsenic Trioxide Arsenic Trioxide results in increased phosphorylation of and results in increased activity of MAP2K6 protein MAP2K6 protein promotes the reaction [Arsenic Trioxide results in increased phosphorylation of and results in increased activity of MAPK14 protein]
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CTD |
PMID:16818652 PMID:26705709 PMID:39716349 |
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NCBI chr10:95,872,747...95,987,747
Ensembl chr10:95,872,546...95,987,721
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| G
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Map3k12
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mitogen activated protein kinase kinase kinase 12
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increases expression
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ISO
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Arsenic Trioxide results in increased expression of MAP3K12 mRNA
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CTD |
PMID:35676786 |
|
NCBI chr 7:135,507,082...135,527,396
Ensembl chr 7:135,508,790...135,515,137
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| G
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Map3k6
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mitogen-activated protein kinase kinase kinase 6
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increases expression
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ISO
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Arsenic Trioxide results in increased expression of MAP3K6 mRNA
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CTD |
PMID:35676786 |
|
NCBI chr 5:150,724,029...150,736,113
Ensembl chr 5:150,724,216...150,736,111
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| G
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Map3k7cl
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MAP3K7 C-terminal like
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increases expression
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ISO
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Arsenic Trioxide results in increased expression of MAP3K7CL mRNA
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CTD |
PMID:26705709 |
|
NCBI chr11:40,276,839...40,321,848
Ensembl chr11:40,277,688...40,321,847
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| G
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Map4k2
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mitogen activated protein kinase kinase kinase kinase 2
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decreases expression multiple interactions
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ISO
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Arsenic Trioxide results in decreased expression of MAP4K2 mRNA Metformin inhibits the reaction [Arsenic Trioxide results in decreased expression of MAP4K2 mRNA]
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CTD |
PMID:29095437 |
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NCBI chr 1:213,074,360...213,090,042
Ensembl chr 1:213,074,377...213,096,987
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| G
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Map4k3
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mitogen-activated protein kinase kinase kinase kinase 3
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increases expression
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ISO
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Arsenic Trioxide results in increased expression of MAP4K3 mRNA
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CTD |
PMID:20458559 |
|
NCBI chr 6:20,029,246...20,198,583
Ensembl chr 6:20,029,397...20,198,583
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| G
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Map7
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microtubule-associated protein 7
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increases expression
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ISO
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Arsenic Trioxide results in increased expression of MAP7 mRNA
|
CTD |
PMID:15761015 |
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NCBI chr 1:16,730,000...16,857,173
Ensembl chr 1:16,730,075...16,857,170
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| G
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Mapk1
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mitogen activated protein kinase 1
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multiple interactions affects activity increases phosphorylation decreases expression affects expression decreases phosphorylation increases activity decreases activity increases expression
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EXP ISO
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2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of MAPK1 protein]; Arsenic Trioxide results in decreased phosphorylation of and results in decreased activity of MAPK1 protein; Arsenic Trioxide results in increased phosphorylation of and results in increased activity of MAPK1 protein; HTS 466284 inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Phloretin inhibits the reaction [Arsenic Trioxide results in decreased expression of MAPK1 mRNA] Arsenic Trioxide affects the activity of MAPK1 protein 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of MAPK1 protein]; [Arsenic Trioxide co-treated with 6,7-dimethoxy-3-phenylquinoxaline] results in decreased activity of MAPK1 protein; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in decreased phosphorylation of MAPK1 protein] Arsenic Trioxide results in decreased expression of MAPK1 protein Arsenic Trioxide affects the expression of MAPK1 mRNA 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [[Arsenic Trioxide co-treated with Tetradecanoylphorbol Acetate] results in increased phosphorylation of and results in increased activity of MAPK1 protein]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of and results in increased activity of MAPK1 protein]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of MAPK1 protein]; 4-((3-bromophenyl)amino)-6,7-dimethoxyquinazoline inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of MAPK1 protein]; 4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of and results in increased activity of MAPK1 protein]; 4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of MAPK1 protein]; [acetyl-11-ketoboswellic acid co-treated with Arsenic Trioxide] results in decreased phosphorylation of MAPK1 protein; [Arsenic Trioxide co-treated with 6,7-dimethoxy-3-phenylquinoxaline] results in decreased activity of MAPK1 protein; [Arsenic Trioxide co-treated with phytosphingosine] results in decreased phosphorylation of MAPK1 protein; [Arsenic Trioxide co-treated with Tetradecanoylphorbol Acetate] results in increased phosphorylation of and results in increased activity of MAPK1 protein; [IL24 protein co-treated with Arsenic Trioxide] results in increased phosphorylation of MAPK1 protein; [Quercetin co-treated with Arsenic Trioxide] results in increased phosphorylation of and results in increased activity of MAPK1 protein; [Sulindac co-treated with Arsenic Trioxide] results in increased phosphorylation of MAPK1 protein; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of MAPK1 protein]; AKT1 protein inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of MAPK1 protein]; ARL6IP5 protein promotes the reaction [Arsenic Trioxide results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Arsenic Trioxide inhibits the reaction [Deoxyglucose results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Arsenic Trioxide inhibits the reaction [FGF2 protein results in increased phosphorylation of MAPK1 protein]; Arsenic Trioxide inhibits the reaction [IGF1 protein results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Arsenic Trioxide inhibits the reaction [Indomethacin results in decreased phosphorylation of MAPK1 protein]; Arsenic Trioxide inhibits the reaction [lonidamine results in increased phosphorylation of MAPK1 protein]; Arsenic Trioxide inhibits the reaction [Sirolimus results in increased phosphorylation of MAPK1 protein]; Arsenic Trioxide inhibits the reaction [temsirolimus results in increased phosphorylation of MAPK1 protein]; Arsenic Trioxide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; Arsenic Trioxide inhibits the reaction [TNF protein results in increased phosphorylation of MAPK1 protein]; Arsenic Trioxide inhibits the reaction [Tunicamycin results in decreased phosphorylation of MAPK1 protein]; Arsenic Trioxide inhibits the reaction [VEGFA protein results in increased phosphorylation of MAPK1 protein]; Arsenic Trioxide promotes the reaction [Curcumin results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Arsenic Trioxide promotes the reaction [MAPK1 protein promotes the reaction [FOS protein binds to CDKN1A promoter]]; Arsenic Trioxide promotes the reaction [Sulindac results in increased phosphorylation of MAPK1 protein]; Arsenic Trioxide promotes the reaction [Tretinoin results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Arsenic Trioxide results in increased phosphorylation of and results in increased activity of MAPK1 protein; bisindolylmaleimide I inhibits the reaction [[Arsenic Trioxide co-treated with Tetradecanoylphorbol Acetate] results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Indomethacin inhibits the reaction [Arsenic Trioxide results in decreased phosphorylation of MAPK1 protein]; KIRA6 inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of MAPK1 protein]; MAPK1 protein affects the reaction [Arsenic Trioxide results in increased expression of CCND1 protein]; MAPK1 protein affects the reaction [Arsenic Trioxide results in increased expression of CDC6 protein]; MAPK8 mutant form inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of MAPK1 protein]; MT2A protein inhibits the reaction [Arsenic Trioxide results in increased expression of MAPK1 protein modified form]; setanaxib inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of MAPK1 protein]; Sorafenib inhibits the reaction [Arsenic Trioxide results in increased activity of MAPK1 protein]; Sulindac promotes the reaction [Arsenic Trioxide results in increased phosphorylation of MAPK1 protein]; temsirolimus inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of MAPK1 protein]; U 0126 inhibits the reaction [[Arsenic Trioxide co-treated with Tetradecanoylphorbol Acetate] results in increased phosphorylation of and results in increased activity of MAPK1 protein]; U 0126 inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of and results in increased activity of MAPK1 protein]; U 0126 inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of MAPK1 protein]; U 0126 promotes the reaction [Arsenic Trioxide results in increased phosphorylation of MAPK1 protein] Arsenic Trioxide results in decreased activity of MAPK1 protein Arsenic Trioxide results in increased expression of MAPK1 mRNA
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CTD |
PMID:11304686 PMID:12296996 PMID:12754411 PMID:14610070 PMID:15580305 PMID:15688020 PMID:15723287 PMID:15761769 PMID:15961274 PMID:16283431 PMID:16328441 PMID:16360329 PMID:16445569 PMID:17050201 PMID:17237268 PMID:17258074 PMID:18281123 PMID:18299328 PMID:18359480 PMID:18387645 PMID:18636201 PMID:18822310 PMID:19088370 PMID:20200477 PMID:20458559 PMID:20592496 PMID:20605902 PMID:20615082 PMID:20799280 PMID:20862710 PMID:21078271 PMID:21145380 PMID:21278055 PMID:21533816 PMID:21594580 PMID:21649584 PMID:21889928 PMID:22532027 PMID:22963400 PMID:23041229 PMID:23253724 PMID:23542815 PMID:23664956 PMID:23832679 PMID:24157283 PMID:24312908 PMID:24392034 PMID:24531206 PMID:25758096 PMID:25791921 PMID:25983101 PMID:27794399 PMID:27829220 PMID:28454374 PMID:30014256 PMID:30091188 PMID:32305283 PMID:32683294 PMID:33462182 PMID:34037972 PMID:34303041 PMID:34560123 PMID:36509116 More...
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NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825
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| G
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Mapk11
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mitogen-activated protein kinase 11
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increases activity multiple interactions
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ISO
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Arsenic Trioxide results in increased activity of MAPK11 protein Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to MAPK11 protein]; MAPK11 protein modified form inhibits the reaction [Arsenic Trioxide results in increased activity of MAPK11 protein]; MAPK11 protein modified form inhibits the reaction [Arsenic Trioxide results in increased activity of MAPKAPK2 protein]
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CTD |
PMID:12239215 PMID:26598702 |
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NCBI chr 7:122,098,120...122,105,023
Ensembl chr 7:122,098,121...122,105,038
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| G
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Mapk13
|
mitogen activated protein kinase 13
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increases expression
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ISO
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Arsenic Trioxide results in increased expression of MAPK13 mRNA
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CTD |
PMID:29633893 |
|
NCBI chr20:6,836,979...6,847,197
Ensembl chr20:6,837,013...6,847,191
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| G
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Mapk14
|
mitogen activated protein kinase 14
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multiple interactions decreases response to substance increases phosphorylation
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ISO
|
Arsenic Trioxide results in increased phosphorylation of and results in increased activity of MAPK14 protein; MAP2K3 protein promotes the reaction [Arsenic Trioxide results in increased phosphorylation of and results in increased activity of MAPK14 protein]; MAP2K6 protein promotes the reaction [Arsenic Trioxide results in increased phosphorylation of and results in increased activity of MAPK14 protein] 3,4-dihydro-5-(4-(1-piperidinyl)butoxy)-1(2H)-isoquinolinone inhibits the reaction [[Arsenic Trioxide co-treated with phytosphingosine] results in increased phosphorylation of MAPK14 protein]; [Arsenic Trioxide co-treated with phytosphingosine] results in increased phosphorylation of MAPK14 protein; Acetylcysteine inhibits the reaction [[Arsenic Trioxide co-treated with phytosphingosine] results in increased phosphorylation of MAPK14 protein]; Acetylcysteine inhibits the reaction [Emodin promotes the reaction [Arsenic Trioxide results in increased phosphorylation of and results in increased activity of MAPK14 protein]]; Arsenic Trioxide results in increased phosphorylation of and results in increased activity of MAPK14 protein; Emodin promotes the reaction [Arsenic Trioxide results in increased phosphorylation of and results in increased activity of MAPK14 protein]; MAPK14 mutant form inhibits the reaction [Arsenic Trioxide affects the localization of BAX protein]; MAPK14 mutant form inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of BCL2 protein]; MAPK14 protein promotes the reaction [Arsenic Trioxide results in increased phosphorylation of and results in increased activity of EIF4E protein]; MAPK14 protein promotes the reaction [Arsenic Trioxide results in increased phosphorylation of and results in increased activity of MKNK1 protein]; MAPK14 protein promotes the reaction [Arsenic Trioxide results in increased phosphorylation of and results in increased activity of MKNK2 protein]; PPM1D mutant form promotes the reaction [Arsenic Trioxide results in increased phosphorylation of and results in increased activity of MAPK14 protein]; SB 203580 inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [Arsenic Trioxide results in increased phosphorylation of and results in increased activity of MAPK14 protein]]; Tetradecanoylphorbol Acetate promotes the reaction [Arsenic Trioxide results in increased phosphorylation of and results in increased activity of MAPK14 protein] MAPK14 results in decreased susceptibility to Arsenic Trioxide Arsenic Trioxide results in increased phosphorylation of MAPK14 protein
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CTD |
PMID:12239215 PMID:14610070 PMID:14729614 PMID:16818652 PMID:16972261 PMID:17237268 PMID:18299328 PMID:18412143 PMID:18482988 PMID:36509116 More...
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NCBI chr20:6,751,288...6,812,294
Ensembl chr20:6,751,357...6,812,294
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| G
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Mapk3
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mitogen activated protein kinase 3
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increases expression decreases phosphorylation multiple interactions increases phosphorylation decreases expression decreases activity increases activity
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EXP ISO
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Arsenic Trioxide results in increased expression of MAPK3 protein modified form Arsenic Trioxide results in decreased phosphorylation of MAPK3 protein 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of MAPK3 protein]; [Arsenic Trioxide co-treated with 6,7-dimethoxy-3-phenylquinoxaline] results in decreased activity of MAPK3 protein; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in decreased phosphorylation of MAPK3 protein] Arsenic Trioxide results in decreased expression of MAPK3 mRNA; Arsenic Trioxide results in decreased expression of MAPK3 protein Arsenic Trioxide results in decreased activity of MAPK3 protein Arsenic Trioxide results in increased activity of MAPK3 protein 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of MAPK3 protein]; Arsenic Trioxide results in decreased phosphorylation of and results in decreased activity of MAPK3 protein; Arsenic Trioxide results in increased phosphorylation of and results in increased activity of MAPK3 protein; HTS 466284 inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Phloretin inhibits the reaction [Arsenic Trioxide results in decreased expression of MAPK3 mRNA] 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [[Arsenic Trioxide co-treated with Tetradecanoylphorbol Acetate] results in increased phosphorylation of and results in increased activity of MAPK3 protein]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of and results in increased activity of MAPK3 protein]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of MAPK3 protein]; 4-((3-bromophenyl)amino)-6,7-dimethoxyquinazoline inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of MAPK3 protein]; 4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of and results in increased activity of MAPK3 protein]; 4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of MAPK3 protein]; [acetyl-11-ketoboswellic acid co-treated with Arsenic Trioxide] results in decreased phosphorylation of MAPK3 protein; [Arsenic Trioxide co-treated with 6,7-dimethoxy-3-phenylquinoxaline] results in decreased activity of MAPK3 protein; [Arsenic Trioxide co-treated with phytosphingosine] results in decreased phosphorylation of MAPK3 protein; [Arsenic Trioxide co-treated with Tetradecanoylphorbol Acetate] results in increased phosphorylation of and results in increased activity of MAPK3 protein; [IL24 protein co-treated with Arsenic Trioxide] results in increased phosphorylation of MAPK3 protein; [Quercetin co-treated with Arsenic Trioxide] results in increased phosphorylation of and results in increased activity of MAPK3 protein; [Sulindac co-treated with Arsenic Trioxide] results in increased phosphorylation of MAPK3 protein; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of MAPK3 protein]; AKT1 protein inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of MAPK3 protein]; ARL6IP5 protein promotes the reaction [Arsenic Trioxide results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Arsenic Trioxide inhibits the reaction [Deoxyglucose results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Arsenic Trioxide inhibits the reaction [FGF2 protein results in increased phosphorylation of MAPK3 protein]; Arsenic Trioxide inhibits the reaction [IGF1 protein results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Arsenic Trioxide inhibits the reaction [Indomethacin results in decreased phosphorylation of MAPK3 protein]; Arsenic Trioxide inhibits the reaction [lonidamine results in increased phosphorylation of MAPK3 protein]; Arsenic Trioxide inhibits the reaction [Sirolimus results in increased phosphorylation of MAPK3 protein]; Arsenic Trioxide inhibits the reaction [temsirolimus results in increased phosphorylation of MAPK3 protein]; Arsenic Trioxide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]; Arsenic Trioxide inhibits the reaction [TNF protein results in increased phosphorylation of MAPK3 protein]; Arsenic Trioxide inhibits the reaction [Tunicamycin results in decreased phosphorylation of MAPK3 protein]; Arsenic Trioxide inhibits the reaction [VEGFA protein results in increased phosphorylation of MAPK3 protein]; Arsenic Trioxide promotes the reaction [Curcumin results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Arsenic Trioxide promotes the reaction [MAPK3 protein promotes the reaction [FOS protein binds to CDKN1A promoter]]; Arsenic Trioxide promotes the reaction [Sulindac results in increased phosphorylation of MAPK3 protein]; Arsenic Trioxide promotes the reaction [Tretinoin results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Arsenic Trioxide results in increased phosphorylation of and results in increased activity of MAPK3 protein; bisindolylmaleimide I inhibits the reaction [[Arsenic Trioxide co-treated with Tetradecanoylphorbol Acetate] results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Indomethacin inhibits the reaction [Arsenic Trioxide results in decreased phosphorylation of MAPK3 protein]; KIRA6 inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of MAPK3 protein]; MAPK3 protein affects the reaction [Arsenic Trioxide results in increased expression of CCND1 protein]; MAPK3 protein affects the reaction [Arsenic Trioxide results in increased expression of CDC6 protein]; MAPK8 mutant form inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of MAPK3 protein]; MT2A protein inhibits the reaction [Arsenic Trioxide results in increased expression of MAPK3 protein modified form]; setanaxib inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of MAPK3 protein]; Sorafenib inhibits the reaction [Arsenic Trioxide results in increased activity of MAPK3 protein]; Sulindac promotes the reaction [Arsenic Trioxide results in increased phosphorylation of MAPK3 protein]; temsirolimus inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of MAPK3 protein]; U 0126 inhibits the reaction [[Arsenic Trioxide co-treated with Tetradecanoylphorbol Acetate] results in increased phosphorylation of and results in increased activity of MAPK3 protein]; U 0126 inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of and results in increased activity of MAPK3 protein]; U 0126 inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of MAPK3 protein]; U 0126 promotes the reaction [Arsenic Trioxide results in increased phosphorylation of MAPK3 protein]
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CTD |
PMID:11304686 PMID:12296996 PMID:12754411 PMID:14610070 PMID:15580305 PMID:15688020 PMID:15723287 PMID:15961274 PMID:16283431 PMID:16328441 PMID:16360329 PMID:16445569 PMID:17050201 PMID:17237268 PMID:18281123 PMID:18299328 PMID:18359480 PMID:18387645 PMID:18636201 PMID:18822310 PMID:19088370 PMID:20164150 PMID:20200477 PMID:20458559 PMID:20592496 PMID:20605902 PMID:20615082 PMID:20799280 PMID:20862710 PMID:21078271 PMID:21145380 PMID:21278055 PMID:21533816 PMID:21594580 PMID:21649584 PMID:21889928 PMID:22532027 PMID:22963400 PMID:23041229 PMID:23253724 PMID:23542815 PMID:23664956 PMID:23832679 PMID:24157283 PMID:24312908 PMID:24392034 PMID:24531206 PMID:25758096 PMID:25791921 PMID:25983101 PMID:27794399 PMID:27829220 PMID:28454374 PMID:30014256 PMID:30091188 PMID:32305283 PMID:32683294 PMID:33462182 PMID:34037972 PMID:34303041 PMID:34560123 PMID:36509116 More...
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NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:190,797,185...190,803,411
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| G
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Mapk7
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mitogen-activated protein kinase 7
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multiple interactions decreases activity
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ISO
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[IL24 protein co-treated with Arsenic Trioxide] results in increased phosphorylation of MAPK7 protein Arsenic Trioxide results in decreased activity of MAPK7 protein
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CTD |
PMID:15580305 PMID:15761769 |
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NCBI chr10:46,669,721...46,675,768
Ensembl chr10:46,669,721...46,675,806
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| G
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Mapk8
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mitogen-activated protein kinase 8
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increases response to substance multiple interactions increases phosphorylation increases activity affects response to substance increases expression
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ISO EXP
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MAPK8 results in increased susceptibility to Arsenic Trioxide Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of MAPK8 protein]; Phloretin inhibits the reaction [Arsenic Trioxide results in increased expression of MAPK8 mRNA]; pyrazolanthrone inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of MAPK8 protein] MAPK8 protein results in increased susceptibility to Arsenic Trioxide; MAPK8 results in increased susceptibility to Arsenic Trioxide [IL24 protein co-treated with Arsenic Trioxide] results in increased phosphorylation of MAPK8 protein; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of MAPK8 protein]; Arsenic Trioxide promotes the reaction [puerarin results in increased expression of MAPK8 protein]; Arsenic Trioxide results in increased phosphorylation of and results in increased activity of MAPK8 protein; Buthionine Sulfoximine promotes the reaction [Arsenic Trioxide results in increased activity of MAPK8 protein]; Dicumarol inhibits the reaction [Arsenic Trioxide results in increased activity of MAPK8 protein]; indole-5-carboxamide promotes the reaction [Arsenic Trioxide results in increased phosphorylation of and results in increased activity of MAPK8 protein]; KIRA6 inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of MAPK8 protein]; MAP2K4 gene mutant form inhibits the reaction [Arsenic Trioxide results in increased activity of MAPK8 protein]; MAPK8 affects the reaction [[Sulindac co-treated with Arsenic Trioxide] results in increased phosphorylation of BCL2L1 protein]; MAPK8 mutant form inhibits the reaction [Arsenic Trioxide results in increased activity of CASP3 protein]; MAPK8 mutant form inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of BCL2 protein]; MAPK8 mutant form inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of MAPK1 protein]; MAPK8 mutant form inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of MAPK3 protein]; MAPK8 mutant form inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of MAPK9 protein]; MAPK8 protein affects the reaction [Arsenic Trioxide results in decreased phosphorylation of and results in decreased activity of AKT1 protein]; MAPK8 protein affects the reaction [Arsenic Trioxide results in increased activity of CASP3 protein]; MAPK8 protein affects the reaction [Arsenic Trioxide results in increased activity of CASP8 protein]; MAPK8 protein affects the reaction [Arsenic Trioxide results in increased activity of CASP9 protein]; MAPK8 protein affects the reaction [Arsenic Trioxide results in increased expression of PTEN protein]; MAPK9 mutant form inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of MAPK8 protein]; pyrazolanthrone inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of MAPK8 protein]; pyrazolanthrone inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [Arsenic Trioxide results in increased phosphorylation of and results in increased activity of MAPK8 protein]]; SB 203580 promotes the reaction [Arsenic Trioxide results in increased phosphorylation of and results in increased activity of MAPK8 protein]; SCIO-469 promotes the reaction [Arsenic Trioxide results in increased phosphorylation of and results in increased activity of MAPK8 protein]; selonsertib inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of MAPK8 protein]; Tetradecanoylphorbol Acetate promotes the reaction [Arsenic Trioxide results in increased phosphorylation of and results in increased activity of MAPK8 protein] MAPK8 protein affects the susceptibility to Arsenic Trioxide Arsenic Trioxide results in increased expression of MAPK8 protein Arsenic Trioxide results in increased expression of MAPK8 mRNA; Arsenic Trioxide results in increased expression of MAPK8 protein
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CTD |
PMID:11304686 PMID:12296996 PMID:12931215 PMID:14610070 PMID:14701702 PMID:15580305 PMID:15688020 PMID:15961274 PMID:16646077 PMID:16818652 PMID:17374990 PMID:18281123 PMID:18412143 PMID:18822310 PMID:20416161 PMID:20534739 PMID:20799280 PMID:21145380 PMID:24466103 PMID:27174766 PMID:31734849 PMID:34037972 PMID:34091186 PMID:34303041 PMID:34560123 PMID:36509116 More...
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NCBI chr16:8,645,171...8,728,225
Ensembl chr16:8,645,198...8,728,427
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| G
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Mapk8ip1
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mitogen-activated protein kinase 8 interacting protein 1
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increases expression multiple interactions
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ISO
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Arsenic Trioxide results in increased expression of MAPK8IP1 protein Arsenic Trioxide inhibits the reaction [AKT1 protein binds to MAPK8IP1 protein]
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CTD |
PMID:18566239 |
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NCBI chr 3:98,810,540...98,829,302
Ensembl chr 3:98,810,541...98,828,368
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| G
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Mapk9
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mitogen-activated protein kinase 9
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increases expression increases phosphorylation multiple interactions increases response to substance increases activity
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ISO EXP
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Arsenic Trioxide results in increased expression of MAPK9 protein Arsenic Trioxide results in increased phosphorylation of MAPK9 protein [Bortezomib co-treated with Arsenic Trioxide] affects the expression of MAPK9 protein; [IL24 protein co-treated with Arsenic Trioxide] results in increased phosphorylation of MAPK9 protein; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of MAPK9 protein]; Arsenic Trioxide results in increased phosphorylation of and results in increased activity of MAPK9 protein; indole-5-carboxamide promotes the reaction [Arsenic Trioxide results in increased phosphorylation of and results in increased activity of MAPK9 protein]; MAPK8 mutant form inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of MAPK9 protein]; MAPK9 mutant form inhibits the reaction [Arsenic Trioxide results in increased activity of CASP3 protein]; MAPK9 mutant form inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of BCL2 protein]; MAPK9 mutant form inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of MAPK8 protein]; pyrazolanthrone inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of MAPK9 protein]; SB 203580 promotes the reaction [Arsenic Trioxide results in increased phosphorylation of and results in increased activity of MAPK9 protein]; SCIO-469 promotes the reaction [Arsenic Trioxide results in increased phosphorylation of and results in increased activity of MAPK9 protein] MAPK9 results in increased susceptibility to Arsenic Trioxide Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of MAPK9 protein]; pyrazolanthrone inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of MAPK9 protein] Arsenic Trioxide results in increased activity of MAPK9 protein MAPK9 protein results in increased susceptibility to Arsenic Trioxide; MAPK9 results in increased susceptibility to Arsenic Trioxide [Arsenic Trioxide results in increased abundance of arsenite] which results in increased phosphorylation of MAPK9 protein
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CTD |
PMID:12296996 PMID:15580305 PMID:15688020 PMID:16818652 PMID:17374990 PMID:18412143 PMID:18718063 PMID:20799280 PMID:21145380 PMID:24466103 PMID:27174766 PMID:36791901 More...
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NCBI chr10:34,670,750...34,711,972
Ensembl chr10:34,670,756...34,712,228
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| G
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Mapkap1
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MAPK associated protein 1
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increases expression
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ISO
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Arsenic Trioxide results in increased expression of MAPKAP1 mRNA
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CTD |
PMID:39716349 |
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NCBI chr 3:38,113,268...38,315,913
Ensembl chr 3:38,113,323...38,315,913
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| G
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Mapkapk2
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MAPK activated protein kinase 2
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decreases expression increases activity multiple interactions
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ISO
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Arsenic Trioxide results in decreased expression of MAPKAPK2 mRNA Arsenic Trioxide results in increased activity of MAPKAPK2 protein MAPK11 protein modified form inhibits the reaction [Arsenic Trioxide results in increased activity of MAPKAPK2 protein]; SB 203580 inhibits the reaction [Arsenic Trioxide results in increased activity of MAPKAPK2 protein]
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CTD |
PMID:12239215 PMID:20458559 |
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NCBI chr13:45,066,027...45,112,326
Ensembl chr13:45,066,031...45,112,326
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| G
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Mapre1
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microtubule-associated protein, RP/EB family, member 1
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increases expression
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ISO
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Arsenic Trioxide results in increased expression of MAPRE1 mRNA
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CTD |
PMID:20458559 |
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NCBI chr 3:162,679,020...162,707,167
Ensembl chr 3:162,673,195...162,711,210
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| G
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Mapt
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microtubule-associated protein tau
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increases expression
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ISO
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Arsenic Trioxide results in increased expression of MAPT protein
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CTD |
PMID:35467087 |
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NCBI chr10:89,638,618...89,736,108
Ensembl chr10:89,638,599...89,736,108
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| G
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Marchf2
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membrane associated ring-CH-type finger 2
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increases expression
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ISO
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Arsenic Trioxide results in increased expression of MARCHF2 mRNA
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CTD |
PMID:15761015 |
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NCBI chr 7:15,183,931...15,209,988
Ensembl chr 7:15,183,925...15,202,002
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| G
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Marchf3
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membrane associated ring-CH-type finger 3
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decreases expression
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ISO
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Arsenic Trioxide results in decreased expression of MARCHF3 mRNA
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CTD |
PMID:20458559 |
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NCBI chr18:52,435,292...52,587,321
Ensembl chr18:52,435,296...52,587,297
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| G
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Marchf4
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membrane associated ring-CH-type finger 4
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increases expression
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ISO
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Arsenic Trioxide results in increased expression of MARCHF4 mRNA
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CTD |
PMID:20458559 |
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NCBI chr 9:81,527,703...81,647,448
Ensembl chr 9:81,527,703...81,647,448
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| G
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Marcks
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myristoylated alanine rich protein kinase C substrate
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increases expression
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ISO
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Arsenic Trioxide results in increased expression of MARCKS protein
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CTD |
PMID:25419056 |
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NCBI chr20:42,240,185...42,245,882
Ensembl chr20:42,240,185...42,245,882
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| G
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Mark3
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microtubule affinity regulating kinase 3
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increases expression
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ISO
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Arsenic Trioxide results in increased expression of MARK3 mRNA
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CTD |
PMID:39716349 |
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NCBI chr 6:136,447,327...136,537,409
Ensembl chr 6:136,448,531...136,537,404
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| G
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Marveld1
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MARVEL domain containing 1
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decreases response to substance multiple interactions increases expression
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ISO
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MARVELD1 protein results in decreased susceptibility to Arsenic Trioxide [MARVELD1 protein results in decreased susceptibility to Arsenic Trioxide] which results in decreased cleavage of CASP3 protein; [MARVELD1 protein results in decreased susceptibility to Arsenic Trioxide] which results in decreased cleavage of PARP1 protein; [MARVELD1 protein results in decreased susceptibility to Arsenic Trioxide] which results in decreased expression of BAX protein; [MARVELD1 protein results in decreased susceptibility to Arsenic Trioxide] which results in increased expression of BCL2 protein; [MARVELD1 protein results in decreased susceptibility to Arsenic Trioxide] which results in increased expression of TXNRD1 mRNA; [MARVELD1 protein results in decreased susceptibility to Arsenic Trioxide] which results in increased expression of TXNRD1 protein; MARVELD1 protein inhibits the reaction [Arsenic Trioxide results in decreased expression of BCL2 protein]; MARVELD1 protein inhibits the reaction [Arsenic Trioxide results in decreased expression of TXNRD1 mRNA]; MARVELD1 protein inhibits the reaction [Arsenic Trioxide results in decreased expression of TXNRD1 protein]; MARVELD1 protein inhibits the reaction [Arsenic Trioxide results in increased cleavage of CASP3 protein]; MARVELD1 protein inhibits the reaction [Arsenic Trioxide results in increased cleavage of PARP1 protein]; MARVELD1 protein inhibits the reaction [Arsenic Trioxide results in increased expression of BAX protein] Arsenic Trioxide results in increased expression of MARVELD1 mRNA
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CTD |
PMID:31205918 PMID:39716349 |
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NCBI chr 1:250,903,342...250,907,393
Ensembl chr 1:250,903,342...250,907,393
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| G
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Mat2b
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methionine adenosyltransferase 2 non-catalytic beta subunit
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multiple interactions
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ISO
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Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to MAT2B protein]
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CTD |
PMID:26598702 |
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NCBI chr10:25,609,202...25,626,694
Ensembl chr10:25,609,204...25,625,176
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| G
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Matk
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megakaryocyte-associated tyrosine kinase
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decreases expression
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ISO
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Arsenic Trioxide results in decreased expression of MATK mRNA
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CTD |
PMID:19128835 |
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NCBI chr 7:9,107,711...9,116,864
Ensembl chr 7:9,107,722...9,112,746
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| G
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Matn1
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matrilin 1
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increases expression
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ISO
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Arsenic Trioxide results in increased expression of MATN1 mRNA
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CTD |
PMID:20458559 |
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NCBI chr 5:148,401,364...148,411,256
Ensembl chr 5:148,401,620...148,411,256
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| G
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Matn2
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matrilin 2
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decreases expression
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ISO
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Arsenic Trioxide results in decreased expression of MATN2 mRNA
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CTD |
PMID:26705709 |
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NCBI chr 7:67,380,140...67,529,767
Ensembl chr 7:67,380,168...67,530,153
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| G
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Mau2
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MAU2 sister chromatid cohesion factor
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decreases expression
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ISO
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Arsenic Trioxide results in decreased expression of MAU2 mRNA
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CTD |
PMID:22521957 |
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NCBI chr16:19,417,812...19,448,922
Ensembl chr16:19,417,613...19,445,841
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| G
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Max
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MYC associated factor X
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affects methylation decreases expression
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ISO
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Arsenic Trioxide affects the methylation of MAX promoter Arsenic Trioxide results in decreased expression of MAX mRNA
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CTD |
PMID:26046465 |
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NCBI chr 6:101,369,989...101,395,333
Ensembl chr 6:101,369,988...101,395,549
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| G
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Mbd2
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methyl-CpG binding domain protein 2
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increases expression multiple interactions
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ISO
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Arsenic Trioxide results in increased expression of MBD2 protein S-Adenosylmethionine inhibits the reaction [Arsenic Trioxide results in increased expression of MBD2 protein]
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CTD |
PMID:22558281 |
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NCBI chr18:66,449,196...66,516,112
Ensembl chr18:66,449,358...66,516,111
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| G
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Mbd3
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methyl-CpG binding domain protein 3
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decreases expression
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ISO
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Arsenic Trioxide results in decreased expression of MBD3 mRNA
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CTD |
PMID:22521957 |
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NCBI chr 7:9,961,053...9,970,845
Ensembl chr 7:9,963,797...9,970,265
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| G
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Mbd4
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methyl-CpG binding domain 4 DNA glycosylase
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increases expression
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ISO
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Arsenic Trioxide results in increased expression of MBD4 mRNA
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CTD |
PMID:20458559 |
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NCBI chr 4:150,565,646...150,577,433
Ensembl chr 4:150,565,655...150,577,578
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| G
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Mbnl2
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muscleblind-like splicing regulator 2
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increases expression
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ISO
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Arsenic Trioxide results in increased expression of MBNL2 mRNA
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CTD |
PMID:22521957 |
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NCBI chr15:103,792,134...103,949,827
Ensembl chr15:103,792,152...103,949,827
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| G
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Mbp
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myelin basic protein
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affects expression
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EXP
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Arsenic Trioxide affects the expression of MBP mRNA
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CTD |
PMID:22954530 |
|
NCBI chr18:78,130,652...78,241,174
Ensembl chr18:78,130,325...78,241,174
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| G
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Mbtd1
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mbt domain containing 1
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decreases expression
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ISO
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Arsenic Trioxide results in decreased expression of MBTD1 mRNA
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CTD |
PMID:35676786 |
|
NCBI chr10:79,336,041...79,392,315
Ensembl chr10:79,335,235...79,392,315
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| G
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Mc1r
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melanocortin 1 receptor
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increases expression
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ISO
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Arsenic Trioxide results in increased expression of MC1R mRNA
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CTD |
PMID:20458559 |
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NCBI chr19:68,360,950...68,363,877
Ensembl chr19:68,360,950...68,363,877
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| G
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Mc2r
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melanocortin 2 receptor
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increases expression
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ISO
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Arsenic Trioxide results in increased expression of MC2R mRNA
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CTD |
PMID:20458559 |
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NCBI chr18:64,279,878...64,291,775
Ensembl chr18:64,277,360...64,291,881
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| G
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Mccc2
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methylcrotonyl-CoA carboxylase subunit 2
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decreases expression
|
ISO
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Arsenic Trioxide results in decreased expression of MCCC2 mRNA
|
CTD |
PMID:39716349 |
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NCBI chr 2:33,039,044...33,110,092
Ensembl chr 2:33,039,045...33,110,299
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| G
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Mcf2l
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MCF.2 cell line derived transforming sequence-like
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decreases expression increases expression
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ISO
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Arsenic Trioxide results in decreased expression of MCF2L mRNA Arsenic Trioxide results in increased expression of MCF2L mRNA
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CTD |
PMID:12852829 PMID:35676786 |
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NCBI chr16:83,209,277...83,355,683
Ensembl chr16:83,209,280...83,354,956
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| G
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Mcl1
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MCL1 apoptosis regulator, BCL2 family member
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decreases expression increases expression multiple interactions
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ISO EXP
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Arsenic Trioxide results in decreased expression of MCL1 mRNA Arsenic Trioxide results in decreased expression of MCL1; Arsenic Trioxide results in decreased expression of MCL1 mRNA; Arsenic Trioxide results in decreased expression of MCL1 protein Arsenic Trioxide results in increased expression of MCL1 mRNA 3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [Arsenic Trioxide results in decreased expression of MCL1 mRNA]; 3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [Arsenic Trioxide results in decreased expression of MCL1 protein]; 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [Arsenic Trioxide results in decreased expression of MCL1 mRNA]; 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [Arsenic Trioxide results in decreased expression of MCL1 protein]; [AKT1 protein co-treated with 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole] inhibits the reaction [Arsenic Trioxide results in decreased expression of MCL1 protein]; [Arsenic Trioxide co-treated with Aprepitant] results in decreased expression of MCL1 mRNA; [Arsenic Trioxide co-treated with sepantronium] results in decreased expression of MCL1 protein; [Curcumin co-treated with Arsenic Trioxide] results in decreased expression of MCL1 protein; [MCL1 mutant form results in increased susceptibility to [Ethacrynic Acid co-treated with Arsenic Trioxide]] which results in increased cleavage of CASP3 protein; [NVP-BKM120 co-treated with Arsenic Trioxide] results in decreased expression of MCL1 mRNA; [Sirolimus co-treated with Arsenic Trioxide] results in decreased expression of MCL1 protein; Acetylcysteine inhibits the reaction [Arsenic Trioxide promotes the reaction [Ethacrynic Acid results in decreased expression of MCL1 protein]]; Arsenic Trioxide inhibits the reaction [BCL2L11 protein binds to MCL1 protein]; Arsenic Trioxide promotes the reaction [Ethacrynic Acid results in decreased expression of MCL1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Arsenic Trioxide promotes the reaction [Ethacrynic Acid results in decreased expression of MCL1 protein]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Arsenic Trioxide results in decreased expression of MCL1 protein]; CAT mutant form promotes the reaction [Arsenic Trioxide promotes the reaction [Ethacrynic Acid results in decreased expression of MCL1 protein]]; MCL1 mutant form promotes the reaction [[Arsenic Trioxide co-treated with Ethacrynic Acid] results in increased cleavage of CASP9 protein]; MCL1 mutant form promotes the reaction [[Arsenic Trioxide co-treated with Ethacrynic Acid] results in increased cleavage of PARP1 protein]; MCL1 mutant form results in increased susceptibility to [Ethacrynic Acid co-treated with Arsenic Trioxide]; MMP9 protein inhibits the reaction [Arsenic Trioxide inhibits the reaction [BCL2L11 protein binds to MCL1 protein]]; MMP9 protein inhibits the reaction [Arsenic Trioxide results in decreased expression of MCL1 protein]; N-(4-methoxybenzyl)-N'-(5-nitro-1,3-thiazol-2-yl)urea inhibits the reaction [Arsenic Trioxide results in decreased expression of MCL1 protein]; NSC 680410 promotes the reaction [Arsenic Trioxide results in decreased expression of MCL1 protein]; pyrazolanthrone inhibits the reaction [Arsenic Trioxide promotes the reaction [Ethacrynic Acid results in decreased expression of MCL1 protein]]; trichostatin A inhibits the reaction [Arsenic Trioxide results in decreased expression of MCL1 protein] Acetylcysteine inhibits the reaction [Arsenic Trioxide results in decreased expression of MCL1 mRNA]
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CTD |
PMID:12883267 PMID:18349030 PMID:19364129 PMID:19549371 PMID:19730151 PMID:19771260 PMID:20723298 PMID:21473291 PMID:21533816 PMID:21889928 PMID:23082001 PMID:23980369 PMID:24956101 PMID:25758096 PMID:30145367 PMID:30316766 PMID:32305283 PMID:34675983 More...
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NCBI chr 2:185,884,840...185,912,532
Ensembl chr 2:185,908,168...185,938,782
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Mcm2
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minichromosome maintenance complex component 2
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increases expression multiple interactions
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ISO
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Arsenic Trioxide results in increased expression of MCM2 mRNA; Arsenic Trioxide results in increased expression of MCM2 protein Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to MCM2 protein]
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CTD |
PMID:17530438 PMID:17547211 PMID:25419056 PMID:26598702 |
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NCBI chr 4:122,903,679...122,918,205
Ensembl chr 4:122,903,682...122,918,094
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Mcm3
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minichromosome maintenance complex component 3
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decreases expression
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ISO
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Arsenic Trioxide results in decreased expression of MCM3 mRNA
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CTD |
PMID:34413873 |
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NCBI chr 9:30,715,602...30,733,746
Ensembl chr 9:30,715,602...30,733,746
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Mcm4
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minichromosome maintenance complex component 4
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increases expression decreases expression
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ISO
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Arsenic Trioxide results in increased expression of MCM4 mRNA; Arsenic Trioxide results in increased expression of MCM4 protein Arsenic Trioxide results in decreased expression of MCM4 mRNA
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CTD |
PMID:19364129 PMID:20458559 PMID:25419056 PMID:34413873 |
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NCBI chr11:98,762,599...98,776,300
Ensembl chr11:98,762,634...98,776,536
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Mcm5
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minichromosome maintenance complex component 5
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decreases expression increases expression
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ISO
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Arsenic Trioxide results in decreased expression of MCM5 mRNA Arsenic Trioxide results in increased expression of MCM5 mRNA
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CTD |
PMID:20458559 PMID:26705709 |
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NCBI chr19:13,488,813...13,510,131
Ensembl chr19:13,488,813...13,517,758
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Mcm6
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minichromosome maintenance complex component 6
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increases expression
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ISO
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Arsenic Trioxide results in increased expression of MCM6 protein
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CTD |
PMID:19364129 |
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NCBI chr13:42,379,161...42,404,352
Ensembl chr13:42,379,162...42,465,467
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Mcm7
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minichromosome maintenance complex component 7
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decreases expression multiple interactions increases expression
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ISO
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Arsenic Trioxide results in decreased expression of MCM7 mRNA; Arsenic Trioxide results in decreased expression of MCM7 protein Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to MCM7 protein] Arsenic Trioxide results in increased expression of MCM7 protein
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CTD |
PMID:19364129 PMID:26598702 PMID:26705709 PMID:34413873 |
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NCBI chr12:22,155,921...22,163,320
Ensembl chr12:22,155,921...22,163,771
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Mcoln3
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mucolipin TRP cation channel 3
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increases expression
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ISO
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Arsenic Trioxide results in increased expression of MCOLN3 mRNA
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CTD |
PMID:20458559 PMID:27829220 |
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NCBI chr 2:237,596,544...237,705,770
Ensembl chr 2:237,626,302...237,705,769
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Mctp1
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multiple C2 and transmembrane domain containing 1
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multiple interactions
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ISO
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[Tretinoin co-treated with Arsenic Trioxide] results in decreased expression of MCTP1 mRNA
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CTD |
PMID:15894607 |
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NCBI chr 2:7,798,968...8,493,596
Ensembl chr 2:7,803,382...8,493,596
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Mctp2
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multiple C2 and transmembrane domain containing 2
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increases expression multiple interactions
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ISO
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Arsenic Trioxide results in increased expression of MCTP2 mRNA Metformin inhibits the reaction [Arsenic Trioxide results in increased expression of MCTP2 mRNA]
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CTD |
PMID:29095437 |
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NCBI chr 1:135,179,845...135,412,798
Ensembl chr 1:135,179,845...135,412,694
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Mcts1
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MCTS1, re-initiation and release factor
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increases expression
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ISO
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Arsenic Trioxide results in increased expression of MCTS1 mRNA
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CTD |
PMID:20458559 |
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NCBI chr X:122,215,602...122,228,101
Ensembl chr X:122,216,439...122,229,631
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Mdfi
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MyoD family inhibitor
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multiple interactions
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ISO
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Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to MDFI protein]
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CTD |
PMID:26598702 |
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NCBI chr 9:20,654,359...20,672,768
Ensembl chr 9:20,654,417...20,672,767
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Mdh1
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malate dehydrogenase 1
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multiple interactions
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ISO
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Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to MDH1 protein]
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CTD |
PMID:26598702 |
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NCBI chr14:99,831,934...99,847,227
Ensembl chr14:99,831,615...99,847,232
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Mdm2
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MDM2 proto-oncogene
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decreases expression multiple interactions increases expression
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EXP ISO
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Arsenic Trioxide results in decreased expression of MDM2 mRNA; Arsenic Trioxide results in decreased expression of MDM2 protein dapagliflozin inhibits the reaction [Arsenic Trioxide results in decreased expression of MDM2 mRNA]; pifithrin inhibits the reaction [Arsenic Trioxide results in increased expression of MDM2 mRNA]
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CTD |
PMID:17487067 PMID:20458559 PMID:20862710 PMID:21145380 PMID:25574600 PMID:26705709 PMID:38070468 More...
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NCBI chr 7:55,176,558...55,201,757
Ensembl chr 7:55,176,560...55,200,791
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Mdm4
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MDM4 regulator of p53
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decreases expression
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ISO
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Arsenic Trioxide results in decreased expression of MDM4 mRNA
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CTD |
PMID:20458559 |
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NCBI chr13:46,922,236...47,068,241
Ensembl chr13:46,958,298...47,026,372
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Mdn1
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midasin AAA ATPase 1
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decreases expression
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ISO
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Arsenic Trioxide results in decreased expression of MDN1 mRNA
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CTD |
PMID:39716349 |
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NCBI chr 5:51,851,785...51,982,688
Ensembl chr 5:51,851,809...51,982,688
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Me1
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malic enzyme 1
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decreases response to substance increases expression multiple interactions
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ISO
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ME1 protein results in decreased susceptibility to Arsenic Trioxide Arsenic Trioxide results in increased expression of ME1 mRNA [Arsenic Trioxide co-treated with Tretinoin] results in increased expression of ME1 mRNA
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CTD |
PMID:15725085 PMID:19417148 PMID:20458559 PMID:20707922 PMID:25258189 PMID:26705709 PMID:38179723 More...
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NCBI chr 8:96,429,057...96,540,244
Ensembl chr 8:96,429,057...96,540,275
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Meaf6
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MYST/Esa1-associated factor 6
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decreases expression
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ISO
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Arsenic Trioxide results in decreased expression of MEAF6 mRNA
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CTD |
PMID:39716349 |
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NCBI chr 5:142,628,281...142,653,076
Ensembl chr 5:142,628,968...142,656,293
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Meak7
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MTOR associated protein, eak-7 homolog
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increases expression
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ISO
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Arsenic Trioxide results in increased expression of MEAK7 mRNA
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CTD |
PMID:15761015 |
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NCBI chr19:64,722,528...64,745,443
Ensembl chr19:64,722,528...64,751,330
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Mecom
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MDS1 and EVI1 complex locus
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increases sumoylation increases response to substance multiple interactions decreases expression
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ISO
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Arsenic Trioxide results in increased sumoylation of MECOM protein MECOM protein results in increased susceptibility to Arsenic Trioxide Arsenic Trioxide results in increased localization of [MECOM protein co-treated with SUMO1 protein] Arsenic Trioxide results in decreased expression of MECOM mRNA; Arsenic Trioxide results in decreased expression of MECOM protein
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CTD |
PMID:15203277 PMID:20458559 PMID:23770046 PMID:24944602 PMID:30472098 |
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NCBI chr 2:114,837,815...115,393,052
Ensembl chr 2:114,837,840...115,393,038
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Mecp2
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methyl CpG binding protein 2
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decreases expression
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EXP
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Arsenic Trioxide results in decreased expression of MECP2 mRNA
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CTD |
PMID:29223816 |
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NCBI chr X:156,932,481...156,995,981
Ensembl chr X:156,941,234...156,943,560
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Med1
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mediator complex subunit 1
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multiple interactions
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ISO
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Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to MED1 protein]
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CTD |
PMID:26598702 |
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NCBI chr10:83,641,851...83,685,560
Ensembl chr10:83,641,862...83,685,545
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Med13
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mediator complex subunit 13
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increases expression
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ISO
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Arsenic Trioxide results in increased expression of MED13 mRNA
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CTD |
PMID:35676786 |
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NCBI chr10:71,584,354...71,674,614
Ensembl chr10:71,584,354...71,673,901
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Med23
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mediator complex subunit 23
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decreases expression
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ISO
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Arsenic Trioxide results in decreased expression of MED23 mRNA
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CTD |
PMID:35676786 |
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NCBI chr 1:22,309,613...22,377,745
Ensembl chr 1:22,309,613...22,356,754
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Med29
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mediator complex subunit 29
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multiple interactions increases expression
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ISO
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Metformin inhibits the reaction [Arsenic Trioxide results in increased expression of MED29 mRNA]
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CTD |
PMID:29095437 |
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NCBI chr 1:92,805,505...92,810,908
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Mef2b
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myocyte enhancer factor 2B
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decreases expression
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ISO
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Arsenic Trioxide results in decreased expression of MEF2B mRNA
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CTD |
PMID:19128835 |
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NCBI chr16:19,286,951...19,305,547
Ensembl chr16:19,286,953...19,302,910
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Meg3
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maternally expressed 3
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multiple interactions increases expression decreases expression decreases methylation
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ISO
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[[Arsenic Trioxide results in increased expression of DNMT3A protein] which results in increased methylation of MEG3 promoter] which results in decreased expression of MEG3 protein; [Arsenic Trioxide results in decreased expression of MEG3 protein] promotes the reaction [NQO1 protein binds to FSCN1 protein]; [Arsenic Trioxide results in decreased expression of MEG3 protein] which results in increased expression of NQO1 protein; MEG3 inhibits the reaction [Arsenic Trioxide results in increased expression of FSCN1 protein]; MEG3 inhibits the reaction [Arsenic Trioxide results in increased expression of NQO1 protein]; MEG3 protein affects the reaction [Arsenic Trioxide results in decreased expression of CDH2 protein]; MEG3 protein affects the reaction [Arsenic Trioxide results in decreased expression of PKM mRNA]; MEG3 protein affects the reaction [Arsenic Trioxide results in decreased expression of PKM protein]; MEG3 protein affects the reaction [Arsenic Trioxide results in decreased expression of VIM protein]; MEG3 protein affects the reaction [Arsenic Trioxide results in increased expression of CDH1 protein]; PKM protein inhibits the reaction [Arsenic Trioxide results in increased expression of MEG3 mRNA] Arsenic Trioxide results in decreased methylation of MEG3 promoter
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CTD |
PMID:31003765 PMID:37424815 |
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NCBI chr 6:134,274,056...134,306,249
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Megf6
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multiple EGF-like-domains 6
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decreases expression
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ISO
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Arsenic Trioxide results in decreased expression of MEGF6 mRNA
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CTD |
PMID:26705709 PMID:35676786 |
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NCBI chr 5:170,020,699...170,121,557
Ensembl chr 5:170,020,778...170,121,554
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Meioc
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meiosis specific with coiled-coil domain
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decreases expression
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ISO
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Arsenic Trioxide results in decreased expression of MEIOC mRNA
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CTD |
PMID:26705709 |
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NCBI chr10:88,128,939...88,147,833
Ensembl chr10:88,128,990...88,147,829
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Meox1
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mesenchyme homeobox 1
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decreases expression
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ISO
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Arsenic Trioxide results in decreased expression of MEOX1 mRNA
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CTD |
PMID:26705709 |
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NCBI chr10:87,318,668...87,338,169
Ensembl chr10:87,318,695...87,337,976
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Mep1a
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meprin A subunit alpha
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increases expression decreases expression
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ISO
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Arsenic Trioxide results in increased expression of MEP1A mRNA Arsenic Trioxide results in decreased expression of MEP1A mRNA
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CTD |
PMID:20458559 PMID:39716349 |
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NCBI chr 9:24,971,901...25,001,414
Ensembl chr 9:24,971,886...25,001,414
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Mertk
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MER proto-oncogene, tyrosine kinase
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increases expression decreases expression
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ISO
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Arsenic Trioxide results in increased expression of MERTK mRNA Arsenic Trioxide results in decreased expression of MERTK mRNA
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CTD |
PMID:20458559 PMID:29633893 |
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NCBI chr 3:136,391,936...136,498,366
Ensembl chr 3:136,383,560...136,500,192
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Mesd
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mesoderm development LRP chaperone
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multiple interactions
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ISO
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Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to MESD protein]
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CTD |
PMID:26598702 |
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NCBI chr 1:147,275,904...147,289,134
Ensembl chr 1:147,275,396...147,289,134
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Met
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MET proto-oncogene, receptor tyrosine kinase
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decreases expression
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ISO
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Arsenic Trioxide results in decreased expression of MET mRNA
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CTD |
PMID:19769630 PMID:20458559 |
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NCBI chr 4:46,756,823...46,864,041
Ensembl chr 4:46,756,506...46,870,821
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Metap1
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methionyl aminopeptidase 1
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multiple interactions
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ISO
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Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to METAP1 protein]
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CTD |
PMID:26598702 |
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NCBI chr 2:229,664,677...229,697,730
Ensembl chr 2:229,664,677...229,719,084
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Mettl1
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methyltransferase 1, tRNA methylguanosine
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multiple interactions
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ISO
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Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to METTL1 protein]
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CTD |
PMID:26598702 |
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NCBI chr 7:64,750,189...64,754,531
Ensembl chr 7:64,750,198...64,754,639
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Mettl14
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methyltransferase 14, N6-adenosine-methyltransferase non-catalytic subunit
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multiple interactions increases expression
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ISO
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Arsenic Trioxide promotes the reaction [METTL14 protein binds to NLRP3 mRNA]; AS3MT mRNA promotes the reaction [Arsenic Trioxide promotes the reaction [METTL14 protein binds to NLRP3 mRNA]]; METTL14 protein promotes the reaction [Arsenic Trioxide inhibits the reaction [INS protein results in increased phosphorylation of GSK3B protein]]; METTL14 protein promotes the reaction [Arsenic Trioxide results in increased expression of CASP1 protein modified form]; METTL14 protein promotes the reaction [Arsenic Trioxide results in increased expression of NLRP3 protein]; METTL14 protein promotes the reaction [Arsenic Trioxide results in increased secretion of IL18 protein]; METTL14 protein promotes the reaction [Arsenic Trioxide results in increased secretion of IL1B protein]; METTL14 protein promotes the reaction [Arsenic Trioxide results in increased stability of NLRP3 mRNA] Arsenic Trioxide results in increased expression of METTL14 protein
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CTD |
PMID:35226250 |
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NCBI chr 2:214,215,165...214,231,412
Ensembl chr 2:214,215,165...214,231,412
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Mettl2
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methyltransferase like 2
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decreases expression
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ISO
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Arsenic Trioxide results in decreased expression of METTL2 mRNA
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CTD |
PMID:35676786 |
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NCBI chr10:90,595,411...90,609,234
Ensembl chr10:90,595,411...90,610,228
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Mettl22
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methyltransferase 22, Kin17 lysine
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multiple interactions decreases expression
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ISO
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Metformin inhibits the reaction [Arsenic Trioxide results in decreased expression of METTL22 mRNA]
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CTD |
PMID:29095437 |
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NCBI chr10:7,620,279...7,637,334
Ensembl chr10:7,620,279...7,638,222
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Mettl27
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methyltransferase like 27
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increases expression
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ISO
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Arsenic Trioxide results in increased expression of METTL27 mRNA
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CTD |
PMID:20458559 |
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NCBI chr12:27,394,067...27,403,220
Ensembl chr12:27,393,678...27,403,202
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Mettl3
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methyltransferase 3, N6-adenosine-methyltransferase complex catalytic subunit
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decreases expression
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ISO
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Arsenic Trioxide results in decreased expression of METTL3 mRNA
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CTD |
PMID:15894607 PMID:34108876 |
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NCBI chr15:27,476,659...27,491,134
Ensembl chr15:27,476,660...27,487,487
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Mex3d
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mex-3 RNA binding family member D
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decreases expression
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ISO
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Arsenic Trioxide results in decreased expression of MEX3D mRNA
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CTD |
PMID:22521957 |
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NCBI chr 7:9,976,253...9,983,383
Ensembl chr 7:9,976,253...9,983,383
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Mfn1
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mitofusin 1
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increases expression multiple interactions
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EXP ISO
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Arsenic Trioxide results in increased expression of MFN1 protein salvianolic acid A inhibits the reaction [Arsenic Trioxide results in increased expression of MFN1 protein]
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CTD |
PMID:29867492 |
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NCBI chr 2:117,240,525...117,288,017
Ensembl chr 2:117,241,759...117,290,190
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Mfn2
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mitofusin 2
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increases expression multiple interactions
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ISO EXP
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Arsenic Trioxide results in increased expression of MFN2 protein salvianolic acid A inhibits the reaction [Arsenic Trioxide results in increased expression of MFN2 protein]
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CTD |
PMID:29867492 |
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NCBI chr 5:163,587,463...163,617,363
Ensembl chr 5:163,587,463...163,618,495
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Mfsd4b2
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major facilitator superfamily domain containing 4B2
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increases expression
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ISO
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Arsenic Trioxide results in increased expression of SLC60A2 mRNA
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CTD |
PMID:20458559 |
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NCBI chr20:44,899,164...44,907,624
Ensembl chr20:44,899,164...44,907,624
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Mgat4b
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alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B
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decreases response to substance
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ISO
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MGAT4B protein results in decreased susceptibility to Arsenic Trioxide
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CTD |
PMID:20707922 |
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NCBI chr10:35,049,421...35,060,307
Ensembl chr10:35,050,512...35,060,309
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Mgp
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matrix Gla protein
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increases expression decreases expression
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ISO
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Arsenic Trioxide results in increased expression of MGP mRNA Arsenic Trioxide results in decreased expression of MGP mRNA
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CTD |
PMID:20458559 PMID:26705709 |
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NCBI chr 4:171,497,472...171,500,888
Ensembl chr 4:171,497,471...171,500,859
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Mgst1
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microsomal glutathione S-transferase 1
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increases expression multiple interactions
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ISO
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Arsenic Trioxide results in increased expression of MGST1 mRNA Arsenic Trioxide promotes the reaction [Lutein results in increased expression of MGST1 mRNA]; Lutein promotes the reaction [Arsenic Trioxide results in increased expression of MGST1 mRNA]
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CTD |
PMID:25815309 PMID:26187899 |
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NCBI chr 4:172,760,930...172,776,157
Ensembl chr 4:172,760,886...172,776,875
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Mib2
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MIB E3 ubiquitin protein ligase 2
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increases expression
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ISO
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Arsenic Trioxide results in increased expression of MIB2 mRNA
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CTD |
PMID:39716349 |
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NCBI chr 5:171,526,037...171,542,479
Ensembl chr 5:171,526,037...171,541,910
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Micb
|
MHC class I polypeptide-related sequence B
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of MICB mRNA; Arsenic Trioxide results in increased expression of MICB protein
|
CTD |
PMID:18463537 PMID:26705709 |
|
NCBI chr 1:87,623,826...87,641,075
Ensembl chr 1:87,623,826...87,640,872
|
|
| G
|
Micu3
|
mitochondrial calcium uptake family, member 3
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to MICU3 protein]
|
CTD |
PMID:26598702 |
|
NCBI chr16:58,624,702...58,714,302
Ensembl chr16:58,629,208...58,714,045
|
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| G
|
Mif
|
macrophage migration inhibitory factor
|
decreases expression multiple interactions
|
ISO
|
Arsenic Trioxide results in decreased expression of MIF protein Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to MIF protein]
|
CTD |
PMID:19364129 PMID:25419056 PMID:26598702 |
|
NCBI chr20:12,767,138...12,791,222
Ensembl chr 4:134,041,774...134,042,121 Ensembl chr20:134,041,774...134,042,121
|
|
| G
|
Mill1
|
MHC I like leukocyte 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of MICA mRNA; Arsenic Trioxide results in increased expression of MICA protein
|
CTD |
PMID:18463537 PMID:22521957 |
|
NCBI chr 1:87,500,591...87,526,983
Ensembl chr 1:87,500,676...87,526,981
|
|
| G
|
Mir100
|
microRNA 100
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of MIR100 mRNA
|
CTD |
PMID:22072212 |
|
NCBI chr 8:50,798,295...50,798,374
Ensembl chr 8:50,798,295...50,798,374
|
|
| G
|
Mir107
|
microRNA 107
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of MIR107 mRNA
|
CTD |
PMID:22967415 |
|
NCBI chr 1:241,750,418...241,750,504
|
|
| G
|
Mir10a
|
microRNA 10a
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of MIR10A mRNA
|
CTD |
PMID:22072212 |
|
NCBI chr10:81,779,709...81,779,818
Ensembl chr10:81,779,709...81,779,818
|
|
| G
|
Mir10b
|
microRNA 10b
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of MIR10B mRNA
|
CTD |
PMID:22072212 |
|
NCBI chr 3:80,035,859...80,035,967
Ensembl chr 3:80,035,859...80,035,967
|
|
| G
|
Mir122
|
microRNA 122
|
increases expression multiple interactions
|
ISO EXP
|
Arsenic Trioxide results in increased expression of MIR122 mRNA Butyrates inhibits the reaction [Arsenic Trioxide results in increased expression of MIR122 mRNA]; MIR122 mRNA affects the reaction [Butyrates inhibits the reaction [Arsenic Trioxide results in decreased expression of OCLN protein]] dapagliflozin inhibits the reaction [Arsenic Trioxide results in increased expression of MIR122 mRNA]
|
CTD |
PMID:22072212 PMID:35676786 PMID:36473683 PMID:38070468 |
|
NCBI chr18:61,028,817...61,028,901
|
|
| G
|
Mir125a
|
microRNA 125a
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of MIR125A mRNA
|
CTD |
PMID:22072212 |
|
NCBI chr 1:67,350,675...67,350,759
Ensembl chr 1:67,350,675...67,350,759
|
|
| G
|
Mir126a
|
microRNA 126a
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of MIR126 mRNA
|
CTD |
PMID:22072212 |
|
NCBI chr 3:29,813,150...29,813,267
|
|
| G
|
Mir128-1
|
microRNA 128-1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of MIR128-1 mRNA
|
CTD |
PMID:22072212 |
|
NCBI chr13:42,251,884...42,251,965
Ensembl chr13:42,251,884...42,251,965
|
|
| G
|
Mir132
|
microRNA 132
|
increases expression multiple interactions
|
ISO EXP
|
Arsenic Trioxide results in increased expression of MIR132 mRNA Nicorandil inhibits the reaction [Arsenic Trioxide results in increased expression of MIR132 mRNA]
|
CTD |
PMID:22072212 PMID:38741475 |
|
NCBI chr10:60,522,033...60,522,133
Ensembl chr10:60,522,033...60,522,133
|
|
| G
|
Mir133b
|
microRNA 133b
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of MIR133B mRNA
|
CTD |
PMID:22072212 |
|
NCBI chr 9:30,594,582...30,594,665
Ensembl chr 9:30,594,582...30,594,665
|
|
| G
|
Mir135a2
|
microRNA 135a-2
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of MIR135A-2 mRNA
|
CTD |
PMID:35676786 |
|
NCBI chr 7:28,499,166...28,499,265
|
|
| G
|
Mir140
|
microRNA 140
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of MIR140 mRNA
|
CTD |
PMID:22072212 |
|
NCBI chr19:52,375,293...52,375,391
Ensembl chr19:52,375,293...52,375,391
|
|
| G
|
Mir143
|
microRNA 143
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of MIR143 mRNA
|
CTD |
PMID:22072212 |
|
NCBI chr18:57,371,349...57,371,453
|
|
| G
|
Mir144
|
microRNA 144
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of MIR144 mRNA
|
CTD |
PMID:22072212 |
|
NCBI chr10:63,459,397...63,459,479
Ensembl chr10:63,459,397...63,459,479
|
|
| G
|
Mir146a
|
microRNA 146a
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of MIR146A mRNA
|
CTD |
PMID:22072212 |
|
NCBI chr10:28,349,996...28,350,090
|
|
| G
|
Mir146b
|
microRNA 146b
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of MIR146B mRNA
|
CTD |
PMID:22072212 |
|
NCBI chr 1:255,144,860...255,144,947
Ensembl chr 1:255,144,860...255,144,947
|
|
| G
|
Mir148a
|
microRNA 148a
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of MIR148A mRNA
|
CTD |
PMID:22072212 |
|
NCBI chr 4:81,664,431...81,664,527
|
|
| G
|
Mir148b
|
microRNA 148b
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of MIR148B mRNA
|
CTD |
PMID:22072212 |
|
NCBI chr 7:136,299,870...136,299,966
Ensembl chr 7:136,299,870...136,299,966
|
|
| G
|
Mir150
|
microRNA 150
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of MIR150 mRNA
|
CTD |
PMID:22072212 |
|
NCBI chr 1:104,741,487...104,741,571
Ensembl chr 1:104,741,487...104,741,571
|
|
| G
|
Mir155
|
microRNA 155
|
increases expression decreases expression multiple interactions
|
ISO
|
Arsenic Trioxide results in increased expression of MIR155 mRNA Arsenic Trioxide results in decreased expression of MIR155 mRNA MIR155 mRNA inhibits the reaction [Arsenic Trioxide results in decreased expression of HMOX1 protein]; MIR155 mRNA inhibits the reaction [Arsenic Trioxide results in decreased expression of NQO1 protein]; MIR155 mRNA inhibits the reaction [Arsenic Trioxide results in increased expression of BACH1 protein]
|
CTD |
PMID:22072212 PMID:29260515 PMID:35676786 |
|
NCBI chr11:37,261,114...37,261,178
Ensembl chr11:37,261,114...37,261,178
|
|
| G
|
Mir15b
|
microRNA 15b
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of MIR15B mRNA
|
CTD |
PMID:22967415 |
|
NCBI chr 2:155,555,178...155,555,275
Ensembl chr 2:155,555,178...155,555,275
|
|
| G
|
Mir17
|
microRNA 17
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of MIR17 mRNA
|
CTD |
PMID:22072212 |
|
NCBI chr15:98,587,848...98,587,931
Ensembl chr15:98,587,848...98,587,931
|
|
| G
|
Mir181a-1
|
microRNA 181a-1
|
multiple interactions increases expression
|
EXP
|
Febuxostat inhibits the reaction [Arsenic Trioxide results in increased expression of MIR181A-1 mRNA]
|
CTD |
PMID:37689273 |
|
NCBI chr13:52,037,067...52,037,166
|
|
| G
|
Mir181c
|
microRNA 181c
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of MIR181C mRNA
|
CTD |
PMID:22072212 |
|
NCBI chr19:40,888,291...40,888,396
Ensembl chr19:40,888,291...40,888,396
|
|
| G
|
Mir181d
|
microRNA 181d
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of MIR181D mRNA
|
CTD |
PMID:22072212 |
|
NCBI chr19:40,888,474...40,888,556
Ensembl chr19:40,888,474...40,888,556
|
|
| G
|
Mir182
|
microRNA 182
|
decreases expression multiple interactions
|
ISO
|
Arsenic Trioxide results in decreased expression of MIR182 mRNA Acetylcysteine inhibits the reaction [Arsenic Trioxide results in decreased expression of MIR182 mRNA]; TGFB1 protein inhibits the reaction [Arsenic Trioxide results in decreased expression of MIR182 mRNA]
|
CTD |
PMID:29662624 |
|
NCBI chr 4:59,752,246...59,752,307
|
|
| G
|
Mir183
|
microRNA 183
|
decreases expression multiple interactions increases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of MIR183 mRNA TGFB1 protein inhibits the reaction [Arsenic Trioxide results in decreased expression of MIR183 mRNA] Arsenic Trioxide results in increased expression of MIR183 mRNA
|
CTD |
PMID:22072212 PMID:29662624 |
|
NCBI chr 4:59,756,044...59,756,153
|
|
| G
|
Mir184
|
microRNA 184
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of MIR184 mRNA
|
CTD |
PMID:22072212 |
|
NCBI chr 8:99,222,982...99,223,058
|
|
| G
|
Mir18a
|
microRNA 18a
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of MIR18A mRNA
|
CTD |
PMID:22072212 |
|
NCBI chr15:98,587,984...98,588,079
Ensembl chr15:98,587,984...98,588,079
|
|
| G
|
Mir191
|
microRNA 191
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of MIR191 mRNA
|
CTD |
PMID:22072212 |
|
NCBI chr 8:118,142,627...118,142,717
|
|
| G
|
Mir193a
|
microRNA 193a
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of MIR193A mRNA
|
CTD |
PMID:22072212 |
|
NCBI chr10:65,170,306...65,170,417
|
|
| G
|
Mir193b
|
microRNA 193b
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of MIR193B mRNA
|
CTD |
PMID:22072212 |
|
NCBI chr10:1,824,944...1,825,026
Ensembl chr10:1,824,944...1,825,026
|
|
| G
|
Mir19a
|
microRNA 19a
|
decreases expression increases expression multiple interactions affects response to substance
|
ISO
|
Arsenic Trioxide results in decreased expression of MIR19A mRNA Arsenic Trioxide results in increased expression of MIR19A mRNA MIR19A inhibits the reaction [Arsenic Trioxide results in increased expression of PTEN protein] MIR19A affects the susceptibility to Arsenic Trioxide
|
CTD |
PMID:20857258 PMID:22072212 |
|
NCBI chr15:98,588,131...98,588,212
Ensembl chr15:98,588,131...98,588,212
|
|
| G
|
Mir1a-1
|
microRNA 1a-1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of MIR1-1 mRNA
|
CTD |
PMID:22072212 |
|
NCBI chr 3:187,864,685...187,864,769
Ensembl chr 3:187,864,685...187,864,769
|
|
| G
|
Mir200c
|
microRNA 200c
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of MIR200C mRNA
|
CTD |
PMID:22072212 |
|
NCBI chr 4:159,209,965...159,210,033
|
|
| G
|
Mir20b
|
microRNA 20b
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of MIR20B mRNA
|
CTD |
PMID:22072212 |
|
NCBI chr X:137,343,197...137,343,268
|
|
| G
|
Mir21
|
microRNA 21
|
decreases response to substance multiple interactions increases expression
|
ISO EXP
|
MIR21 results in decreased susceptibility to Arsenic Trioxide ATF3 promotes the reaction [Arsenic Trioxide results in increased expression of MIR21 protein]; MIR21 mRNA promotes the reaction [Arsenic Trioxide results in decreased expression of KCNH2 protein]; MIR21 mRNA promotes the reaction [Arsenic Trioxide results in decreased expression of SP1 protein]; NFE2L2 promotes the reaction [Arsenic Trioxide results in increased expression of MIR21 protein] Arsenic Trioxide results in increased expression of MIR21; Arsenic Trioxide results in increased expression of MIR21 mRNA dapagliflozin inhibits the reaction [Arsenic Trioxide results in increased expression of MIR21 mRNA]
|
CTD |
PMID:21187093 PMID:22072212 PMID:25395240 PMID:38070468 PMID:38295932 |
|
NCBI chr10:71,902,600...71,902,691
|
|
| G
|
Mir210
|
microRNA 210
|
increases expression multiple interactions
|
ISO
|
Arsenic Trioxide results in increased expression of MIR210 mRNA Arsenic Trioxide inhibits the reaction [PRAM1 protein results in decreased expression of MIR210 mRNA]
|
CTD |
PMID:18941112 PMID:21175813 |
|
NCBI chr 1:205,755,923...205,756,032
Ensembl chr 1:205,755,917...205,756,034
|
|
| G
|
Mir212
|
microRNA 212
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of MIR212 mRNA
|
CTD |
PMID:22072212 |
|
NCBI chr10:60,521,740...60,521,850
Ensembl chr10:60,521,740...60,521,850
|
|
| G
|
Mir214
|
microRNA 214
|
increases expression decreases expression
|
ISO
|
Arsenic Trioxide results in increased expression of MIR214 mRNA Arsenic Trioxide results in decreased expression of MIR214 mRNA
|
CTD |
PMID:22072212 PMID:26705709 |
|
NCBI chr13:77,121,645...77,121,752
Ensembl chr13:77,121,643...77,121,752
|
|
| G
|
Mir216a
|
microRNA 216a
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of MIR216A mRNA
|
CTD |
PMID:35676786 |
|
NCBI chr14:106,725,077...106,725,182
Ensembl chr14:106,725,077...106,725,182
|
|
| G
|
Mir222
|
microRNA 222
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of MIR222 mRNA
|
CTD |
PMID:20857258 |
|
NCBI chr X:6,022,621...6,022,723
Ensembl chr X:6,022,621...6,022,723
|
|
| G
|
Mir223
|
microRNA 223
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of MIR223 mRNA
|
CTD |
PMID:22967415 |
|
NCBI chr X:65,151,383...65,151,492
Ensembl chr X:65,151,383...65,151,492
|
|
| G
|
Mir23a
|
microRNA 23a
|
increases expression multiple interactions
|
EXP ISO
|
Arsenic Trioxide results in increased expression of MIR23A mRNA Arsenic Trioxide inhibits the reaction [PRAM1 protein results in decreased expression of MIR23A mRNA]; MIR23A mRNA promotes the reaction [Arsenic Trioxide results in decreased expression of and affects the localization of and results in decreased activity of KCNH2 protein]
|
CTD |
PMID:18941112 PMID:25395240 |
|
NCBI chr19:40,859,769...40,859,843
|
|
| G
|
Mir23b
|
microRNA 23b
|
increases expression multiple interactions decreases expression
|
ISO EXP
|
Arsenic Trioxide results in increased expression of MIR23B mRNA Febuxostat inhibits the reaction [Arsenic Trioxide results in decreased expression of MIR23B mRNA]
|
CTD |
PMID:22072212 PMID:37689273 |
|
NCBI chr17:1,819,386...1,819,482
|
|
| G
|
Mir27a
|
microRNA 27a
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of MIR27A mRNA
|
CTD |
PMID:22072212 |
|
NCBI chr19:40,859,603...40,859,689
|
|
| G
|
Mir27b
|
microRNA 27b
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of MIR27B mRNA
|
CTD |
PMID:22072212 |
|
NCBI chr17:1,819,147...1,819,243
|
|
| G
|
Mir295-1
|
microRNA 295-1
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of MIR372 mRNA
|
CTD |
PMID:22072212 |
|
NCBI chr 1:74,877,973...74,878,053
|
|
| G
|
Mir29a
|
microRNA 29a
|
multiple interactions increases expression
|
ISO
|
MIR29A protein affects the reaction [Arsenic Trioxide results in decreased expression of PPM1D protein] Arsenic Trioxide results in increased expression of MIR29A mRNA
|
CTD |
PMID:21175813 PMID:22072212 |
|
NCBI chr 4:60,617,955...60,618,042
|
|
| G
|
Mir30a
|
microRNA 30a
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of MIR30A mRNA
|
CTD |
PMID:21175813 |
|
NCBI chr 9:33,233,941...33,234,011
Ensembl chr 9:33,233,941...33,234,011
|
|
| G
|
Mir32
|
microRNA 32
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of MIR32 mRNA
|
CTD |
PMID:22072212 |
|
NCBI chr 5:76,391,285...76,391,354
|
|
| G
|
Mir342
|
microRNA 342
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of MIR342 mRNA
|
CTD |
PMID:22967415 |
|
NCBI chr 6:133,329,655...133,329,753
Ensembl chr 6:133,329,655...133,329,753
|
|
| G
|
Mir34a
|
microRNA 34a
|
increases expression multiple interactions decreases expression
|
ISO
|
Arsenic Trioxide results in increased expression of MIR34A mRNA MIR34A affects the reaction [Arsenic Trioxide results in decreased expression of BCL2 protein]; MIR34A affects the reaction [Arsenic Trioxide results in decreased expression of SIRT1 protein]; MIR34A affects the reaction [Arsenic Trioxide results in increased expression of BAX protein]; Propranolol inhibits the reaction [Arsenic Trioxide results in increased expression of MIR34A mRNA] Arsenic Trioxide results in decreased expression of MIR34A mRNA
|
CTD |
PMID:35676786 PMID:36707890 |
|
NCBI chr 5:165,815,952...165,816,053
Ensembl chr 5:165,815,952...165,816,053
|
|
| G
|
Mir34c
|
microRNA 34c
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of MIR34C mRNA
|
CTD |
PMID:22072212 |
|
NCBI chr 8:60,306,091...60,306,167
|
|
| G
|
Mir363
|
microRNA 363
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of MIR363 mRNA
|
CTD |
PMID:22072212 |
|
NCBI chr X:137,342,777...137,342,863
|
|
| G
|
Mir582
|
microRNA 582
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of MIR582 mRNA
|
CTD |
PMID:35676786 |
|
NCBI chr 2:42,661,954...42,662,034
Ensembl chr 2:42,661,954...42,662,034
|
|
| G
|
Mir96
|
microRNA 96
|
decreases expression increases expression multiple interactions
|
ISO
|
Arsenic Trioxide results in decreased expression of MIR96 mRNA Arsenic Trioxide results in increased expression of MIR96 mRNA TGFB1 protein inhibits the reaction [Arsenic Trioxide results in decreased expression of MIR96 mRNA]
|
CTD |
PMID:22072212 PMID:29662624 |
|
NCBI chr 4:59,755,841...59,755,946
|
|
| G
|
Mir98
|
microRNA 98
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of MIR98 mRNA
|
CTD |
PMID:22072212 |
|
NCBI chr X:24,460,648...24,460,755
Ensembl chr X:24,460,648...24,460,755
|
|
| G
|
Mirlet7d
|
microRNA let-7d
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of MIRLET7D mRNA
|
CTD |
PMID:22072212 |
|
NCBI chr17:16,322,260...16,322,357
Ensembl chr17:16,322,260...16,322,357
|
|
| G
|
Mirlet7g
|
microRNA let-7g
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of MIRLET7G mRNA
|
CTD |
PMID:22072212 |
|
NCBI chr 8:115,701,020...115,701,107
Ensembl chr 8:115,701,007...115,701,115
|
|
| G
|
Misp
|
mitotic spindle positioning
|
decreases response to substance
|
ISO
|
MISP protein results in decreased susceptibility to Arsenic Trioxide
|
CTD |
PMID:20707922 |
|
NCBI chr 7:10,526,980...10,537,159
Ensembl chr 7:10,503,209...10,537,159
|
|
| G
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Mki67
|
marker of proliferation Ki-67
|
decreases expression multiple interactions
|
ISO
|
Arsenic Trioxide results in decreased expression of MKI67 mRNA; Arsenic Trioxide results in decreased expression of MKI67 protein 3-(2,4-dichloro-5-methoxyphenyl)-2-sulfanyl-4(3H)-quinazolinone inhibits the reaction [Arsenic Trioxide results in decreased expression of MKI67 mRNA]; Arsenic Trioxide promotes the reaction [Ascorbic Acid results in decreased expression of MKI67 protein]; Ascorbic Acid promotes the reaction [Arsenic Trioxide results in decreased expression of MKI67 protein] FOXO3 protein affects the reaction [Arsenic Trioxide results in decreased expression of MKI67 protein]
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CTD |
PMID:27318970 PMID:30091188 PMID:31421153 PMID:38160894 |
|
NCBI chr 1:199,926,150...199,952,847
Ensembl chr 1:199,926,150...199,952,593
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| G
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Mknk1
|
MAPK interacting serine/threonine kinase 1
|
affects binding multiple interactions decreases response to substance decreases expression increases activity increases expression
|
ISO
|
Arsenic Trioxide binds to MKNK1 protein [Arsenic Trioxide results in increased phosphorylation of and results in increased activity of MKNK1 protein] which results in increased phosphorylation of EIF4E protein; Arsenic Trioxide results in increased phosphorylation of and results in increased activity of MKNK1 protein; CGP 57380 inhibits the reaction [[Arsenic Trioxide results in increased phosphorylation of and results in increased activity of MKNK1 protein] which results in increased phosphorylation of EIF4E protein]; MAPK14 protein promotes the reaction [Arsenic Trioxide results in increased phosphorylation of and results in increased activity of MKNK1 protein]; MKNK1 protein affects the reaction [Arsenic Trioxide results in increased phosphorylation of EIF4E protein]; MKNK1 protein promotes the reaction [Arsenic Trioxide results in increased phosphorylation of and results in increased activity of EIF4E protein] MKNK1 protein results in decreased susceptibility to Arsenic Trioxide Arsenic Trioxide results in decreased expression of MKNK1 mRNA Arsenic Trioxide results in increased activity of MKNK1 protein Arsenic Trioxide results in increased expression of MKNK1 mRNA
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CTD |
PMID:18299328 PMID:20458559 PMID:21461292 PMID:29042487 |
|
NCBI chr 5:134,554,881...134,594,392
Ensembl chr 5:134,554,943...134,594,393
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| G
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Mknk2
|
MAPK interacting serine/threonine kinase 2
|
multiple interactions decreases response to substance
|
ISO
|
Arsenic Trioxide results in increased phosphorylation of and results in increased activity of MKNK2 protein; MAPK14 protein promotes the reaction [Arsenic Trioxide results in increased phosphorylation of and results in increased activity of MKNK2 protein]; MKNK2 protein promotes the reaction [Arsenic Trioxide results in increased phosphorylation of and results in increased activity of EIF4E protein] MKNK2 protein results in decreased susceptibility to Arsenic Trioxide
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CTD |
PMID:18299328 |
|
NCBI chr 7:9,690,385...9,701,527
Ensembl chr 7:9,690,421...9,701,529
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| G
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Mkrn2
|
makorin, ring finger protein, 2
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of MKRN2 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 4:150,334,164...150,352,271
Ensembl chr 4:150,334,142...150,352,263
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| G
|
Mkrn3
|
makorin, ring finger protein, 3
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of MKRN3 mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr 1:125,338,664...125,341,178
Ensembl chr 1:125,338,564...125,341,164
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|
| G
|
Mlf1
|
myeloid leukemia factor 1
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of MLF1 mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr 2:153,958,060...153,991,705
Ensembl chr 2:153,958,546...153,994,220
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|
| G
|
Mlip
|
muscular LMNA-interacting protein
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of MLIP mRNA
|
CTD |
PMID:26705709 |
|
NCBI chr 8:86,815,491...87,085,117
Ensembl chr 8:86,814,798...87,082,408
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|
| G
|
Mlkl
|
mixed lineage kinase domain like pseudokinase
|
increases phosphorylation decreases expression
|
ISO
|
Arsenic Trioxide results in increased phosphorylation of MLKL protein Arsenic Trioxide results in decreased expression of MLKL mRNA
|
CTD |
PMID:36509116 PMID:37230480 |
|
NCBI chr19:56,186,860...56,213,886
Ensembl chr19:56,186,860...56,213,858
|
|
| G
|
Mllt10
|
MLLT10, histone lysine methyltransferase DOT1L cofactor
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of MLLT10 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr17:85,729,964...85,857,791
Ensembl chr17:85,730,751...85,857,789
|
|
| G
|
Mllt11
|
MLLT11, transcription factor 7 cofactor
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of MLLT11 mRNA
|
CTD |
PMID:25258189 |
|
NCBI chr 2:185,484,791...185,493,961
Ensembl chr 2:185,484,793...185,493,961
|
|
| G
|
Mlph
|
melanophilin
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of MLPH mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr 9:98,955,036...98,990,566
Ensembl chr 9:98,955,141...98,990,556
|
|
| G
|
Mmd
|
monocyte to macrophage differentiation-associated
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of MMD mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr10:75,570,366...75,598,610
Ensembl chr10:75,570,397...75,598,609
|
|
| G
|
Mmp1
|
matrix metallopeptidase 1
|
decreases expression multiple interactions
|
ISO
|
Arsenic Trioxide results in decreased expression of MMP1 mRNA [acetyl-11-ketoboswellic acid co-treated with Arsenic Trioxide] results in decreased activity of MMP1 protein; [acetyl-11-ketoboswellic acid co-treated with Arsenic Trioxide] results in decreased expression of MMP1 mRNA; [acetyl-11-ketoboswellic acid co-treated with Arsenic Trioxide] results in decreased secretion of MMP1 protein; Arsenic Trioxide inhibits the reaction [TNF protein results in increased expression of MMP1 mRNA]; Arsenic Trioxide inhibits the reaction [TNF protein results in increased secretion of and results in increased activity of MMP1 protein]
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CTD |
PMID:15761015 PMID:21078271 PMID:23253724 |
|
NCBI chr 8:12,943,453...12,963,966
Ensembl chr 8:12,943,453...12,963,964
|
|
| G
|
Mmp12
|
matrix metallopeptidase 12
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of MMP12 mRNA
|
CTD |
PMID:19128835 |
|
NCBI chr 8:12,866,652...12,876,554
Ensembl chr 8:12,866,641...12,884,478
|
|
| G
|
Mmp13
|
matrix metallopeptidase 13
|
decreases expression increases expression decreases secretion
|
ISO EXP
|
Arsenic Trioxide results in decreased expression of MMP13 mRNA Arsenic Trioxide results in increased expression of MMP13 mRNA Arsenic Trioxide results in decreased secretion of MMP13 protein
|
CTD |
PMID:26705709 PMID:31734849 PMID:34108876 |
|
NCBI chr 8:12,782,829...12,793,108
Ensembl chr 8:12,782,813...12,793,105
|
|
| G
|
Mmp14
|
matrix metallopeptidase 14
|
decreases expression multiple interactions affects expression
|
ISO EXP
|
Arsenic Trioxide results in decreased expression of MMP14 mRNA; Arsenic Trioxide results in decreased expression of MMP14 protein Arsenic Trioxide promotes the reaction [Berberine results in decreased expression of MMP14 protein] [Arsenic Trioxide co-treated with Silybin] results in decreased expression of MMP14 mRNA; Arsenic Trioxide inhibits the reaction [Silybin results in increased expression of MMP14 mRNA] Arsenic Trioxide affects the expression of MMP14 mRNA
|
CTD |
PMID:15962302 PMID:18294404 PMID:21969006 PMID:27039805 |
|
NCBI chr15:31,857,824...31,867,049
Ensembl chr15:31,857,546...31,869,893
|
|
| G
|
Mmp16
|
matrix metallopeptidase 16
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of MMP16 mRNA
|
CTD |
PMID:25258189 |
|
NCBI chr 5:36,109,265...36,353,252
Ensembl chr 5:36,109,265...36,353,252
|
|
| G
|
Mmp2
|
matrix metallopeptidase 2
|
increases activity increases expression decreases activity multiple interactions decreases expression
|
ISO EXP
|
Arsenic Trioxide results in increased activity of MMP2 protein Arsenic Trioxide results in increased expression of MMP2 protein Arsenic Trioxide results in decreased activity of MMP2 protein Arsenic Trioxide promotes the reaction [Berberine results in decreased activity of MMP2 protein]; Arsenic Trioxide promotes the reaction [Berberine results in decreased expression of MMP2 protein]; Berberine promotes the reaction [Arsenic Trioxide results in decreased activity of MMP2 protein] [acetyl-11-ketoboswellic acid co-treated with Arsenic Trioxide] results in decreased activity of MMP2 protein; [acetyl-11-ketoboswellic acid co-treated with Arsenic Trioxide] results in decreased expression of MMP2 mRNA; [acetyl-11-ketoboswellic acid co-treated with Arsenic Trioxide] results in decreased secretion of MMP2 protein; [Arsenic Trioxide co-treated with Silybin] results in decreased activity of MMP2 protein; [Arsenic Trioxide co-treated with Silybin] results in decreased expression of MMP2 mRNA; [Erlotinib Hydrochloride co-treated with Arsenic Trioxide] results in decreased expression of MMP2 mRNA; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in decreased expression of MMP2 mRNA]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in decreased secretion of MMP2 protein]; Arsenic Trioxide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of MMP2 protein]; Arsenic Trioxide inhibits the reaction [TNF protein results in increased expression of MMP2 mRNA]; Arsenic Trioxide inhibits the reaction [TNF protein results in increased secretion of and results in increased activity of MMP2 protein]; Arsenic Trioxide promotes the reaction [Berberine results in decreased activity of MMP2 protein]; Arsenic Trioxide results in decreased expression of and results in decreased secretion of MMP2 protein; Berberine promotes the reaction [Arsenic Trioxide results in decreased activity of MMP2 protein]; Celecoxib promotes the reaction [Arsenic Trioxide results in decreased expression of MMP2 mRNA]; Celecoxib promotes the reaction [Arsenic Trioxide results in decreased expression of MMP2 protein]; GH1 protein promotes the reaction [Arsenic Trioxide results in decreased expression of MMP2 mRNA]; MIR491 mRNA affects the reaction [Arsenic Trioxide results in decreased expression of MMP2 mRNA]; Silybin promotes the reaction [Arsenic Trioxide results in decreased expression of MMP2 mRNA] Arsenic Trioxide results in decreased expression of MMP2 mRNA; Arsenic Trioxide results in decreased expression of MMP2 protein
|
CTD |
PMID:15553829 PMID:15962302 PMID:16624393 PMID:17512576 PMID:18294404 PMID:19236750 PMID:19822495 PMID:21078271 PMID:21540248 PMID:21969006 PMID:23232515 PMID:23253724 PMID:23851143 PMID:24680928 PMID:25728215 PMID:27039805 PMID:29274334 PMID:30748021 More...
|
|
NCBI chr19:30,327,643...30,355,856
Ensembl chr19:30,327,643...30,355,856
|
|
| G
|
Mmp28
|
matrix metallopeptidase 28
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of MMP28 mRNA
|
CTD |
PMID:15761015 PMID:26705709 |
|
NCBI chr10:68,738,651...68,762,377
Ensembl chr10:68,738,651...68,824,884
|
|
| G
|
Mmp3
|
matrix metallopeptidase 3
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of MMP3 mRNA
|
CTD |
PMID:34108876 |
|
NCBI chr 8:12,925,267...12,938,828
Ensembl chr 8:12,925,280...12,938,826
|
|
| G
|
Mmp7
|
matrix metallopeptidase 7
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of MMP7 mRNA
|
CTD |
PMID:19128835 PMID:26966376 PMID:28901456 |
|
NCBI chr 8:13,133,043...13,140,761
Ensembl chr 8:13,133,043...13,140,755
|
|
| G
|
Mmp9
|
matrix metallopeptidase 9
|
multiple interactions decreases expression increases expression decreases activity decreases response to substance
|
ISO
|
[acetyl-11-ketoboswellic acid co-treated with Arsenic Trioxide] results in decreased activity of MMP9 protein; [acetyl-11-ketoboswellic acid co-treated with Arsenic Trioxide] results in decreased expression of MMP9 mRNA; [acetyl-11-ketoboswellic acid co-treated with Arsenic Trioxide] results in decreased secretion of MMP9 protein; [Arsenic Trioxide co-treated with apatinib] results in decreased expression of MMP9 protein; [Arsenic Trioxide co-treated with Silybin] results in decreased expression of MMP9 mRNA; [Erlotinib Hydrochloride co-treated with Arsenic Trioxide] results in decreased expression of MMP9 mRNA; [Silybin co-treated with Arsenic Trioxide] results in decreased activity of MMP9 protein; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in decreased expression of MMP9 mRNA]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in decreased secretion of MMP9 protein]; Arsenic Trioxide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]; Arsenic Trioxide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of and results in increased activity of MMP9 protein]; Arsenic Trioxide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of MMP9 protein]; Arsenic Trioxide results in decreased expression of and results in decreased secretion of MMP9 protein; Arsenic Trioxide results in increased expression of and affects the localization of and results in decreased secretion of MMP9 protein; benzyloxycarbonyl-valyl-alanyl-aspartyl-fluoromethane inhibits the reaction [Arsenic Trioxide results in increased expression of and affects the localization of MMP9 protein]; benzyloxycarbonyl-valyl-alanyl-aspartyl-fluoromethane inhibits the reaction [Arsenic Trioxide results in increased expression of MMP9 mRNA]; Dactinomycin inhibits the reaction [Arsenic Trioxide results in increased expression of MMP9 mRNA]; GH1 protein promotes the reaction [Arsenic Trioxide results in decreased activity of MMP9 protein]; GH1 protein promotes the reaction [Arsenic Trioxide results in decreased expression of MMP9 mRNA]; HMOX1 protein inhibits the reaction [Arsenic Trioxide results in increased expression of MMP9 mRNA]; HMOX1 protein inhibits the reaction [Arsenic Trioxide results in increased expression of MMP9 protein]; JUN protein promotes the reaction [Arsenic Trioxide results in increased expression of MMP9 mRNA]; JUN protein promotes the reaction [Arsenic Trioxide results in increased expression of MMP9 protein]; MIR491 mRNA affects the reaction [Arsenic Trioxide results in decreased expression of MMP9 mRNA]; MMP9 protein inhibits the reaction [Arsenic Trioxide inhibits the reaction [BCL2L11 protein binds to MCL1 protein]]; MMP9 protein inhibits the reaction [Arsenic Trioxide results in decreased expression of BCL2L1 protein]; MMP9 protein inhibits the reaction [Arsenic Trioxide results in decreased expression of MCL1 protein]; MMP9 protein inhibits the reaction [Arsenic Trioxide results in increased expression of BAX protein]; MMP9 protein inhibits the reaction [Arsenic Trioxide results in increased expression of BCL2L11 protein]; SB 203580 inhibits the reaction [Arsenic Trioxide results in increased expression of MMP9 mRNA]; SB 203580 inhibits the reaction [Arsenic Trioxide results in increased expression of MMP9 protein]; SR 11302 inhibits the reaction [Arsenic Trioxide results in increased expression of MMP9 mRNA]; SR 11302 inhibits the reaction [Arsenic Trioxide results in increased expression of MMP9 protein]; zinc protoporphyrin promotes the reaction [Arsenic Trioxide results in increased expression of MMP9 protein] Arsenic Trioxide results in decreased expression of MMP9 mRNA; Arsenic Trioxide results in decreased expression of MMP9 protein Arsenic Trioxide results in increased expression of MMP9; Arsenic Trioxide results in increased expression of MMP9 mRNA; Arsenic Trioxide results in increased expression of MMP9 protein MMP9 protein results in decreased susceptibility to Arsenic Trioxide
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CTD |
PMID:15949266 PMID:15962302 PMID:16624393 PMID:19128835 PMID:19236750 PMID:19350554 PMID:19804631 PMID:20471514 PMID:20592496 PMID:21078271 PMID:21969006 PMID:23210436 PMID:23253724 PMID:23851143 PMID:24680928 PMID:24956101 PMID:25728215 PMID:26238599 PMID:26705709 PMID:27039805 PMID:27829220 PMID:29274334 PMID:39223679 More...
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|
NCBI chr 3:174,103,474...174,111,434
Ensembl chr 3:174,084,123...174,111,442
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|
| G
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Mnd1
|
meiotic nuclear divisions 1
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of MND1 mRNA
|
CTD |
PMID:26705709 |
|
NCBI chr 2:171,731,523...171,794,124
Ensembl chr 2:171,731,523...171,794,095
|
|
| G
|
Mnt
|
MAX network transcriptional repressor
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of MNT mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr10:60,197,654...60,213,221
Ensembl chr10:60,197,948...60,213,209
|
|
| G
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Mocos
|
molybdenum cofactor sulfurase
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of MOCOS mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr18:16,206,402...16,251,928
Ensembl chr18:16,206,402...16,251,928
|
|
| G
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Mpdu1
|
mannose-P-dolichol utilization defect 1
|
multiple interactions
|
ISO
|
[Tretinoin co-treated with Arsenic Trioxide] results in increased expression of MPDU1 mRNA
|
CTD |
PMID:15894607 |
|
NCBI chr10:54,873,467...54,880,536
Ensembl chr10:54,873,473...54,879,195
|
|
| G
|
Mpl
|
MPL proto-oncogene, thrombopoietin receptor
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of MPL mRNA
|
CTD |
PMID:15761015 |
|
NCBI chr 5:137,259,288...137,281,540
Ensembl chr 5:137,259,288...137,272,177
|
|
| G
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Mpo
|
myeloperoxidase
|
multiple interactions decreases expression increases expression increases activity
|
ISO EXP
|
Arsenic Trioxide promotes the reaction [1,2-Dimethylhydrazine results in increased activity of MPO protein]; Taurine inhibits the reaction [Arsenic Trioxide results in increased expression of MPO protein] [Tretinoin co-treated with Arsenic Trioxide co-treated with Butyrates] results in decreased expression of MPO mRNA; [Tretinoin co-treated with Arsenic Trioxide co-treated with hexamethylene bisacetamide] results in decreased expression of MPO mRNA; [Tretinoin co-treated with Arsenic Trioxide] results in decreased expression of MPO mRNA; Arsenic Trioxide inhibits the reaction [Tretinoin results in decreased expression of MPO protein] Arsenic Trioxide results in decreased expression of MPO protein dapagliflozin inhibits the reaction [Arsenic Trioxide results in increased activity of MPO protein]; Febuxostat inhibits the reaction [Arsenic Trioxide results in increased expression of MPO protein]; Taurine inhibits the reaction [Arsenic Trioxide results in increased expression of MPO protein]
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CTD |
PMID:11133770 PMID:12130515 PMID:20693187 PMID:30090573 PMID:30237538 PMID:30660605 PMID:37689273 PMID:38070468 More...
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|
NCBI chr10:73,092,124...73,102,057
Ensembl chr10:73,092,400...73,102,056
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|
| G
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Mpp4
|
MAGUK p55 scaffold protein 4
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of MPP4 mRNA
|
CTD |
PMID:26705709 |
|
NCBI chr 9:68,063,867...68,103,050
Ensembl chr 9:68,063,867...68,106,128
|
|
| G
|
Mpped2
|
metallophosphoesterase domain containing 2
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of MPPED2 mRNA
|
CTD |
PMID:26705709 |
|
NCBI chr 3:113,635,614...113,810,307
Ensembl chr 3:113,635,407...113,811,783
|
|
| G
|
Mpz
|
myelin protein zero
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of MPZ mRNA
|
CTD |
PMID:27829220 |
|
NCBI chr13:86,103,290...86,109,156
Ensembl chr13:86,103,290...86,109,155
|
|
| G
|
Mr1
|
major histocompatibility complex, class I-related
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of MR1 mRNA
|
CTD |
PMID:22521957 |
|
NCBI chr13:69,850,420...69,868,302
Ensembl chr13:69,850,420...69,868,502
|
|
| G
|
Mrap2
|
melanocortin 2 receptor accessory protein 2
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of MRAP2 mRNA
|
CTD |
PMID:26705709 |
|
NCBI chr 8:96,968,239...97,024,581
Ensembl chr 8:96,988,079...97,024,579
|
|
| G
|
Mrc2
|
mannose receptor, C type 2
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of MRC2 mRNA
|
CTD |
PMID:21461292 |
|
NCBI chr10:90,761,751...90,823,055
Ensembl chr10:90,761,878...90,823,055
|
|
| G
|
Mrpl17
|
mitochondrial ribosomal protein L17
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of MRPL17 protein
|
CTD |
PMID:25419056 |
|
NCBI chr 1:169,574,010...169,575,699
Ensembl chr 1:169,574,010...169,575,818
|
|
| G
|
Mrpl24
|
mitochondrial ribosomal protein L24
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of MRPL24 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 2:175,680,872...175,687,107
Ensembl chr 2:175,681,070...175,688,660
|
|
| G
|
Mrpl30
|
mitochondrial ribosomal protein L30
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of MRPL30 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 9:47,621,226...47,631,986
Ensembl chr 9:47,621,227...47,633,484
|
|
| G
|
Mrpl37
|
mitochondrial ribosomal protein L37
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to MRPL37 protein]
|
CTD |
PMID:26598702 |
|
NCBI chr 5:127,056,679...127,075,000
Ensembl chr 5:127,058,716...127,074,980
|
|
| G
|
Mrpl42
|
mitochondrial ribosomal protein L42
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of MRPL42 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 7:32,004,863...32,028,640
Ensembl chr 7:32,004,777...32,035,104
|
|
| G
|
Mrpl49
|
mitochondrial ribosomal protein L49
|
decreases response to substance
|
ISO
|
MRPL49 protein results in decreased susceptibility to Arsenic Trioxide
|
CTD |
PMID:20707922 |
|
NCBI chr 1:212,775,357...212,779,364
Ensembl chr 1:212,775,357...212,779,888
|
|
| G
|
Mrpl57
|
mitochondrial ribosomal protein L57
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of MRPL57 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr15:36,086,457...36,087,319
Ensembl chr15:36,086,457...36,087,298
|
|
| G
|
Mrps12
|
mitochondrial ribosomal protein S12
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of MRPS12 protein
|
CTD |
PMID:19364129 |
|
NCBI chr 1:93,153,424...93,156,422
Ensembl chr 1:93,153,425...93,159,629
|
|
| G
|
Mrps16
|
mitochondrial ribosomal protein S16
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of MRPS16 mRNA
|
CTD |
PMID:14703492 |
|
NCBI chr15:3,967,809...3,970,211
Ensembl chr15:3,968,054...3,970,185
|
|
| G
|
Mrps2
|
mitochondrial ribosomal protein S2
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of MRPS2 mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr 3:32,201,037...32,204,317
Ensembl chr 3:32,198,641...32,204,892
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| G
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Mrps30
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mitochondrial ribosomal protein S30
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increases expression
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ISO
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Arsenic Trioxide results in increased expression of MRPS30 mRNA
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CTD |
PMID:20458559 PMID:22521957 |
|
NCBI chr 2:52,189,049...52,196,136
Ensembl chr 2:52,189,058...52,195,904
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| G
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Ms4a4a
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membrane spanning 4-domains A4A
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increases expression
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ISO
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Arsenic Trioxide results in increased expression of MS4A4A mRNA
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CTD |
PMID:35676786 |
|
NCBI chr 1:217,495,704...217,510,019
Ensembl chr 1:217,487,996...217,510,503
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| G
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Ms4a6a
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membrane spanning 4-domains A6A
|
increases expression
|
ISO
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Arsenic Trioxide results in increased expression of MS4A6A mRNA
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CTD |
PMID:20458559 |
|
NCBI chr 1:217,826,261...217,839,606
Ensembl chr 1:217,826,261...217,850,013
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| G
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Ms4a8
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membrane spanning 4-domains A8
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decreases expression
|
ISO
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Arsenic Trioxide results in decreased expression of MS4A8 mRNA
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CTD |
PMID:39716349 |
|
NCBI chr 1:217,155,557...217,169,151
Ensembl chr 1:217,155,557...217,169,215
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| G
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Msc
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musculin
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decreases expression
|
ISO
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Arsenic Trioxide results in decreased expression of MSC mRNA
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CTD |
PMID:15761015 |
|
NCBI chr 5:9,330,522...9,336,391
Ensembl chr 5:9,330,544...9,336,857
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| G
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Msh2
|
mutS homolog 2
|
multiple interactions
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ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to MSH2 protein]
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CTD |
PMID:26598702 |
|
NCBI chr 6:12,567,368...12,626,534
Ensembl chr 6:12,567,368...12,626,503
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| G
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Msi1
|
musashi RNA-binding protein 1
|
multiple interactions
|
ISO
|
Arsenic Trioxide promotes the reaction [MSI1 protein binds to EIF2AK2 protein modified form]; Arsenic Trioxide promotes the reaction [MSI1 protein binds to EIF2S1 protein modified form]; Arsenic Trioxide promotes the reaction [MSI1 protein results in increased expression of KLF4 protein]; Arsenic Trioxide promotes the reaction [MSI1 protein results in increased expression of MYC protein]; Arsenic Trioxide promotes the reaction [MSI1 protein results in increased expression of POU5F1 protein]; Arsenic Trioxide promotes the reaction [MSI1 protein results in increased expression of SOX2 protein]; EIF2AK2 protein affects the reaction [Arsenic Trioxide promotes the reaction [MSI1 protein results in increased expression of KLF4 protein]]; EIF2AK2 protein affects the reaction [Arsenic Trioxide promotes the reaction [MSI1 protein results in increased expression of MYC protein]]; EIF2AK2 protein affects the reaction [Arsenic Trioxide promotes the reaction [MSI1 protein results in increased expression of POU5F1 protein]]; EIF2AK2 protein affects the reaction [Arsenic Trioxide promotes the reaction [MSI1 protein results in increased expression of SOX2 protein]]; EIF2AK2 protein affects the reaction [MSI1 protein promotes the reaction [Arsenic Trioxide results in increased phosphorylation of EIF2S1 protein]]; EIF2S1 protein affects the reaction [Arsenic Trioxide promotes the reaction [MSI1 protein results in increased expression of KLF4 protein]]; EIF2S1 protein affects the reaction [Arsenic Trioxide promotes the reaction [MSI1 protein results in increased expression of MYC protein]]; EIF2S1 protein affects the reaction [Arsenic Trioxide promotes the reaction [MSI1 protein results in increased expression of POU5F1 protein]]; EIF2S1 protein affects the reaction [Arsenic Trioxide promotes the reaction [MSI1 protein results in increased expression of SOX2 protein]]; EIF2S1 protein affects the reaction [MSI1 protein promotes the reaction [Arsenic Trioxide results in increased phosphorylation of EIF2AK2 protein]]; MSI1 protein affects the reaction [Arsenic Trioxide results in increased expression of KLF4 protein]; MSI1 protein affects the reaction [Arsenic Trioxide results in increased expression of MYC protein]; MSI1 protein affects the reaction [Arsenic Trioxide results in increased expression of POU5F1 protein]; MSI1 protein affects the reaction [Arsenic Trioxide results in increased expression of SOX2 protein]; MSI1 protein inhibits the reaction [Arsenic Trioxide results in increased activity of CASP3 protein]; MSI1 protein promotes the reaction [Arsenic Trioxide results in increased phosphorylation of EIF2AK2 protein]; MSI1 protein promotes the reaction [Arsenic Trioxide results in increased phosphorylation of EIF2S1 protein]
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CTD |
PMID:29486283 |
|
NCBI chr12:46,815,225...46,911,852
Ensembl chr12:46,819,039...46,845,425
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| G
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Msl1
|
MSL complex subunit 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of MSL1 mRNA
|
CTD |
PMID:35676786 |
|
NCBI chr10:84,251,362...84,263,384
Ensembl chr10:84,251,642...84,261,971
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|
| G
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Msl2
|
MSL complex subunit 2
|
increases response to substance
|
ISO
|
MSL2 protein results in increased susceptibility to Arsenic Trioxide
|
CTD |
PMID:20707922 |
|
NCBI chr 8:110,555,579...110,642,096
Ensembl chr 8:110,555,271...110,647,889
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| G
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Msmo1
|
methylsterol monooxygenase 1
|
multiple interactions decreases expression
|
ISO
|
[Dasatinib co-treated with Arsenic Trioxide] results in decreased expression of MSMO1 mRNA; [Tretinoin co-treated with Arsenic Trioxide] results in decreased expression of MSMO1 mRNA Arsenic Trioxide results in decreased expression of MSMO1 mRNA
|
CTD |
PMID:15894607 PMID:29266867 |
|
NCBI chr16:29,747,113...29,764,360
Ensembl chr16:29,747,137...29,764,445
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| G
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Msn
|
moesin
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of MSN protein
|
CTD |
PMID:25419056 |
|
NCBI chr X:65,005,546...65,073,512
Ensembl chr X:65,005,458...65,075,129
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| G
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Msr1
|
macrophage scavenger receptor 1
|
decreases expression multiple interactions
|
ISO
|
Arsenic Trioxide results in decreased expression of MSR1 mRNA Arsenic Trioxide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MSR1 mRNA]; Thioctic Acid inhibits the reaction [Arsenic Trioxide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MSR1 mRNA]]
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CTD |
PMID:20458559 PMID:21315065 |
|
NCBI chr16:59,421,250...59,507,070
Ensembl chr16:59,421,057...59,507,070
|
|
| G
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Msra
|
methionine sulfoxide reductase A
|
increases expression affects expression
|
ISO
|
Arsenic Trioxide results in increased expression of MSRA mRNA; Arsenic Trioxide results in increased expression of MSRA protein Arsenic Trioxide affects the expression of MSRA protein
|
CTD |
PMID:31473893 |
|
NCBI chr15:42,514,818...42,853,278
Ensembl chr15:42,527,045...42,853,279
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| G
|
Msrb1
|
methionine sulfoxide reductase B1
|
affects expression
|
ISO
|
Arsenic Trioxide affects the expression of MSRB1 mRNA; Arsenic Trioxide affects the expression of MSRB1 protein
|
CTD |
PMID:31473893 |
|
NCBI chr10:14,269,414...14,275,140
Ensembl chr10:14,269,414...14,274,184
|
|
| G
|
Msrb2
|
methionine sulfoxide reductase B2
|
decreases expression affects expression
|
ISO
|
Arsenic Trioxide results in decreased expression of MSRB2 mRNA Arsenic Trioxide affects the expression of MSRB2 mRNA
|
CTD |
PMID:15725085 PMID:31473893 |
|
NCBI chr17:86,882,750...86,908,392
Ensembl chr17:86,882,394...86,908,391
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| G
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Mst1r
|
macrophage stimulating 1 receptor
|
decreases response to substance
|
ISO
|
MST1R protein results in decreased susceptibility to Arsenic Trioxide
|
CTD |
PMID:20707922 |
|
NCBI chr 8:117,471,928...117,491,059
Ensembl chr 8:117,475,968...117,490,515
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| G
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Msx2
|
msh homeobox 2
|
decreases response to substance
|
ISO
|
MSX2 protein results in decreased susceptibility to Arsenic Trioxide
|
CTD |
PMID:20707922 |
|
NCBI chr17:11,102,284...11,107,949
Ensembl chr17:11,102,247...11,107,945
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|
| G
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Mt-atp6
|
mitochondrially encoded ATP synthase membrane subunit 6
|
decreases expression increases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of ATP6 mRNA Arsenic Trioxide results in increased expression of ATP6 mRNA
|
CTD |
PMID:14703492 PMID:15949261 |
|
NCBI chr MT:7,919...8,599
Ensembl chr MT:7,904...8,584
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| G
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Mt-nd4
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mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 4
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of ND4 mRNA
|
CTD |
PMID:14703492 |
|
NCBI chr MT:10,160...11,537
Ensembl chr MT:10,145...11,522
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|
| G
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Mt1-ps3
|
metallothionein 1, pseudogene 3
|
increases expression decreases expression affects expression
|
ISO
|
Arsenic Trioxide results in increased expression of MT1E mRNA Arsenic Trioxide results in decreased expression of MT1E mRNA Arsenic Trioxide affects the expression of MT1E mRNA
|
CTD |
PMID:15725085 PMID:19128835 PMID:19417148 PMID:22555517 PMID:25873331 PMID:26705709 PMID:27829220 More...
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|
NCBI chr17:79,695,812...79,696,200
Ensembl chr17:79,695,809...79,696,200
|
|
| G
|
Mt1a
|
metallothionein 1A
|
affects response to substance decreases expression increases expression
|
ISO
|
MT1A SNP affects the susceptibility to Arsenic Trioxide Arsenic Trioxide results in decreased expression of MT1A mRNA Arsenic Trioxide results in increased expression of MT1A mRNA Arsenic Trioxide results in increased expression of MT1X mRNA
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CTD |
PMID:19128835 PMID:22555517 PMID:24924344 PMID:27829220 PMID:39716349 |
|
NCBI chr19:10,831,959...10,832,975
Ensembl chr17:79,695,809...79,696,200 Ensembl chr X:79,695,809...79,696,200 Ensembl chr19:79,695,809...79,696,200
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|
| G
|
Mt2
|
metallothionein 2
|
decreases expression decreases response to substance multiple interactions increases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of MT2A mRNA MT2A protein results in decreased susceptibility to Arsenic Trioxide [Arsenic Trioxide co-treated with Tretinoin] results in increased expression of MT2A mRNA; Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to MT2A protein]; Atrazine promotes the reaction [Arsenic Trioxide results in increased expression of MT2A mRNA]; MT2A protein inhibits the reaction [Arsenic Trioxide results in increased expression of BAX protein]; MT2A protein inhibits the reaction [Arsenic Trioxide results in increased expression of CASP12 protein modified form]; MT2A protein inhibits the reaction [Arsenic Trioxide results in increased expression of CASP3 protein modified form]; MT2A protein inhibits the reaction [Arsenic Trioxide results in increased expression of MAPK1 protein modified form]; MT2A protein inhibits the reaction [Arsenic Trioxide results in increased expression of MAPK3 protein modified form]; MT2A protein promotes the reaction [Arsenic Trioxide results in increased expression of DDIT3 protein] Arsenic Trioxide results in increased expression of MT2A mRNA; Arsenic Trioxide results in increased expression of MT2A protein Arsenic Trioxide results in increased expression of MT1E mRNA; Arsenic Trioxide results in increased expression of MT1F mRNA; Arsenic Trioxide results in increased expression of MT1G mRNA; Arsenic Trioxide results in increased expression of MT2A mRNA
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CTD |
PMID:11678611 PMID:14682389 PMID:15725085 PMID:19128835 PMID:19417148 PMID:20458559 PMID:22521957 PMID:22555517 PMID:23664956 PMID:24356939 PMID:26598702 PMID:26705709 PMID:27829220 PMID:38179723 PMID:39716349 More...
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|
NCBI chr19:10,837,934...10,838,708
Ensembl chr19:10,837,927...10,838,709
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| G
|
Mt2-ps1
|
metallothionein 2, pseudogene 1
|
increases expression
|
ISO
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Arsenic Trioxide results in increased expression of MT1HL1 mRNA
|
CTD |
PMID:15725085 PMID:26705709 |
|
NCBI chr20:3,163,749...3,164,121
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|
| G
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Mt3
|
metallothionein 3
|
multiple interactions decreases expression
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to MT3 protein] Arsenic Trioxide results in decreased expression of MT3 mRNA
|
CTD |
PMID:22555517 PMID:26598702 |
|
NCBI chr19:10,854,676...10,856,080
Ensembl chr19:10,854,677...10,856,080
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| G
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Mta1
|
metastasis associated 1
|
decreases expression increases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of MTA1 mRNA Arsenic Trioxide results in increased expression of MTA1 mRNA
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CTD |
PMID:12478894 PMID:20458559 PMID:35676786 PMID:39716349 |
|
NCBI chr 6:137,999,845...138,038,696
Ensembl chr 6:137,999,915...138,038,696
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| G
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Mtap
|
methylthioadenosine phosphorylase
|
multiple interactions decreases expression increases expression
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to MTAP protein] Arsenic Trioxide results in decreased expression of MTAP protein Arsenic Trioxide results in increased expression of MTAP mRNA
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CTD |
PMID:19364129 PMID:22521957 PMID:26598702 |
|
NCBI chr 5:108,990,270...109,036,494
Ensembl chr 5:108,988,830...109,055,214
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| G
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Mtarc2
|
mitochondrial amidoxime reducing component 2
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of MTARC2 mRNA
|
CTD |
PMID:35676786 |
|
NCBI chr13:98,894,347...98,928,754
Ensembl chr13:98,897,108...98,928,781
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| G
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Mtch2
|
mitochondrial carrier 2
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of MTCH2 mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr 3:97,286,388...97,306,028
Ensembl chr 3:97,285,894...97,307,327
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| G
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Mtcl3
|
MTCL family member 3
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of MTCL3 mRNA
|
CTD |
PMID:26705709 |
|
NCBI chr 1:30,469,698...30,530,205
Ensembl chr 1:30,453,046...30,529,122
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| G
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Mterf3
|
mitochondrial transcription termination factor 3
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of MTERF3 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 7:65,711,654...65,729,926
Ensembl chr 7:65,711,662...65,729,895
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|
| G
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Mtf1
|
metal-regulatory transcription factor 1
|
affects response to substance
|
ISO
|
MTF1 gene mutant form affects the susceptibility to Arsenic Trioxide
|
CTD |
PMID:30815697 |
|
NCBI chr 5:142,347,024...142,391,810
Ensembl chr 5:142,347,054...142,391,810
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|
| G
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Mtf2
|
metal response element binding transcription factor 2
|
increases response to substance multiple interactions decreases expression
|
ISO
|
MTF2 protein results in increased susceptibility to Arsenic Trioxide Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to MTF2 protein] Arsenic Trioxide results in decreased expression of MTF2 mRNA
|
CTD |
PMID:20707922 PMID:26598702 PMID:35676786 |
|
NCBI chr14:1,784,218...1,828,463
Ensembl chr14:1,783,627...1,828,414
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|
| G
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Mtfr1l
|
mitochondrial fission regulator 1-like
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to MTFR1L protein]
|
CTD |
PMID:26598702 |
|
NCBI chr 5:152,020,617...152,030,417
Ensembl chr 5:152,020,622...152,030,417
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|
| G
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Mthfd1
|
methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1
|
decreases expression multiple interactions
|
ISO
|
Arsenic Trioxide results in decreased expression of MTHFD1 mRNA Arsenic Trioxide results in increased sumoylation of and results in increased degradation of MTHFD1 protein; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Arsenic Trioxide results in increased degradation of MTHFD1 protein]
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CTD |
PMID:20458559 PMID:28265077 |
|
NCBI chr 6:100,713,510...100,781,013
Ensembl chr 6:100,713,681...100,781,957
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|
| G
|
Mthfd1l
|
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of MTHFD1L mRNA
|
CTD |
PMID:22521957 |
|
NCBI chr 1:42,849,424...43,038,313
Ensembl chr 1:42,849,374...43,038,309
|
|
| G
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Mthfd2
|
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of MTHFD2 mRNA
|
CTD |
PMID:24356939 |
|
NCBI chr 4:117,368,833...117,380,350
Ensembl chr 4:117,368,835...117,380,350
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|
| G
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Mtif3
|
mitochondrial translational initiation factor 3
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of MTIF3 mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr12:13,240,091...13,251,350
Ensembl chr12:13,240,173...13,254,373
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|
| G
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Mtmr11
|
myotubularin related protein 11
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of MTMR11 mRNA
|
CTD |
PMID:29633893 |
|
NCBI chr 2:186,410,851...186,421,024
Ensembl chr 2:186,412,291...186,421,026
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|
| G
|
Mtmr2
|
myotubularin related protein 2
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of MTMR2 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 8:18,899,303...18,949,767
Ensembl chr 8:18,928,126...18,949,766
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| G
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Mtor
|
mechanistic target of rapamycin kinase
|
decreases expression decreases phosphorylation multiple interactions increases expression affects expression increases phosphorylation
|
ISO EXP
|
Arsenic Trioxide results in decreased expression of MTOR mRNA; Arsenic Trioxide results in decreased expression of MTOR protein Arsenic Trioxide results in decreased phosphorylation of MTOR protein [Arsenic Trioxide co-treated with apatinib] results in decreased phosphorylation of MTOR protein; Arsenic Trioxide inhibits the reaction [Sorafenib results in increased expression of MTOR protein]; Gemcitabine promotes the reaction [Arsenic Trioxide results in decreased phosphorylation of MTOR protein]; GRB10 protein promotes the reaction [[Arsenic Trioxide co-treated with apatinib] results in decreased phosphorylation of MTOR protein] Arsenic Trioxide results in increased expression of MTOR mRNA Arsenic Trioxide affects the expression of MTOR mRNA 3-methyladenine inhibits the reaction [Arsenic Trioxide results in decreased phosphorylation of MTOR protein]; Sirolimus promotes the reaction [Arsenic Trioxide results in decreased phosphorylation of MTOR protein] Arsenic Trioxide results in increased phosphorylation of MTOR protein dapagliflozin inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of MTOR protein]
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CTD |
PMID:21594580 PMID:25416439 PMID:25449439 PMID:29633893 PMID:30032600 PMID:30225639 PMID:32112876 PMID:32781346 PMID:33462182 PMID:36400307 PMID:38070468 PMID:39223679 More...
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|
NCBI chr 5:164,167,985...164,277,438
Ensembl chr 5:164,167,928...164,277,435
|
|
| G
|
Mtr
|
5-methyltetrahydrofolate-homocysteine methyltransferase
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of MTR protein
|
CTD |
PMID:15894607 |
|
NCBI chr17:62,911,705...62,996,544
Ensembl chr17:62,911,771...62,996,541
|
|
| G
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Mtrex
|
Mtr4 exosome RNA helicase
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of MTREX mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 2:46,233,528...46,293,827
Ensembl chr 2:46,194,647...46,293,827
|
|
| G
|
Mtrf1l
|
mitochondrial translation release factor 1 like
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of MTRF1L mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr 1:44,614,162...44,626,367
Ensembl chr 1:44,615,921...44,626,178
|
|
| G
|
Mtus1
|
microtubule associated scaffold protein 1
|
decreases response to substance
|
ISO
|
MTUS1 protein results in decreased susceptibility to Arsenic Trioxide
|
CTD |
PMID:20707922 |
|
NCBI chr16:57,905,991...58,051,466
Ensembl chr16:57,906,128...58,051,474
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|
| G
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Mtx1
|
Metaxin 1
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of MTX1 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 2:176,913,225...176,919,148
Ensembl chr 2:176,913,225...176,918,824
|
|
| G
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Muc2
|
mucin 2, oligomeric mucus/gel-forming
|
multiple interactions
|
ISO
|
[Arsenic Trioxide results in increased abundance of arsenite] which results in increased expression of MUC2 mRNA; [Arsenic Trioxide results in increased abundance of arsenite] which results in increased expression of MUC2 protein
|
CTD |
PMID:36791901 |
|
NCBI chr 1:206,225,775...206,261,280
Ensembl chr 1:206,229,035...206,261,280
|
|
| G
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Muc3a
|
mucin 3A, cell surface associated
|
decreases response to substance
|
ISO
|
MUC3A protein results in decreased susceptibility to Arsenic Trioxide
|
CTD |
PMID:20707922 |
|
NCBI chr12:25,082,728...25,091,494
Ensembl chr12:25,082,837...25,097,265
|
|
| G
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Mug2
|
murinoglobulin 2
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of PZP mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 4:156,836,140...156,908,972
|
|
| G
|
Mus81
|
MUS81 structure-specific endonuclease subunit
|
multiple interactions increases sumoylation affects response to substance
|
ISO
|
MUS81 protein mutant form inhibits the reaction [Arsenic Trioxide results in increased expression of H2AX protein modified form] Arsenic Trioxide results in increased sumoylation of MUS81 protein [MUS81 protein affects the susceptibility to Arsenic Trioxide] which affects the susceptibility to Camptothecin; [MUS81 protein affects the susceptibility to Arsenic Trioxide] which affects the susceptibility to olaparib; MUS81 protein affects the susceptibility to Arsenic Trioxide
|
CTD |
PMID:28318385 PMID:37530740 |
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NCBI chr 1:212,219,793...212,225,214
Ensembl chr 1:212,219,795...212,225,068
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| G
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Mutyh
|
mutY DNA glycosylase
|
affects activity
|
ISO
|
MUTYH protein affects the activity of Arsenic Trioxide
|
CTD |
PMID:17101720 |
|
NCBI chr 5:135,510,666...135,522,777
Ensembl chr 5:135,517,695...135,522,776
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| G
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Mvp
|
major vault protein
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of MVP protein Arsenic Trioxide results in increased expression of MVP mRNA
|
CTD |
PMID:25419056 PMID:39716349 |
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NCBI chr 1:191,025,259...191,052,866
Ensembl chr 1:191,025,268...191,052,873
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| G
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Mx1
|
MX dynamin like GTPase 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of MX1 protein Arsenic Trioxide results in increased expression of MX1 mRNA
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CTD |
PMID:19364129 PMID:35676786 |
|
NCBI chr11:50,269,056...50,294,699
Ensembl chr11:50,269,057...50,292,904
|
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| G
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Mxd1
|
max dimerization protein 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of MXD1 mRNA
|
CTD |
PMID:25258189 PMID:26705709 |
|
NCBI chr 4:120,654,731...120,678,972
Ensembl chr 4:120,654,731...120,675,129
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| G
|
Mxra7
|
matrix remodeling associated 7
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of MXRA7 mRNA
|
CTD |
PMID:17547211 |
|
NCBI chr10:102,501,848...102,530,231
Ensembl chr10:102,489,604...102,530,231
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| G
|
Mybbp1a
|
MYB binding protein 1a
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of MYBBP1A protein
|
CTD |
PMID:25419056 |
|
NCBI chr10:57,555,458...57,565,819
Ensembl chr10:57,555,452...57,566,041
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|
| G
|
Mybl1
|
MYB proto-oncogene like 1
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of MYBL1 mRNA
|
CTD |
PMID:15725085 PMID:25258189 PMID:26705709 |
|
NCBI chr 5:14,365,768...14,401,012
Ensembl chr 5:14,365,768...14,399,588
|
|
| G
|
Mybph
|
myosin binding protein H
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to MYBPH protein]
|
CTD |
PMID:26598702 |
|
NCBI chr13:48,205,162...48,212,928
Ensembl chr13:48,205,269...48,212,928
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| G
|
Myc
|
MYC proto-oncogene, bHLH transcription factor
|
affects methylation multiple interactions decreases expression increases expression affects expression
|
ISO EXP
|
Arsenic Trioxide affects the methylation of MYC promoter [Genistein co-treated with Arsenic Trioxide] results in decreased expression of MYC protein Arsenic Trioxide results in decreased expression of MYC mRNA; Arsenic Trioxide results in decreased expression of MYC protein [Arsenic Trioxide co-treated with apatinib] results in decreased expression of MYC protein; [Arsenic Trioxide co-treated with Aprepitant] results in decreased expression of MYC mRNA; [Arsenic Trioxide co-treated with Cisplatin] results in decreased expression of MYC mRNA; [Arsenic Trioxide co-treated with Cisplatin] results in decreased expression of MYC protein; [Arsenic Trioxide co-treated with Tretinoin] results in decreased expression of MYC mRNA; [Arsenic Trioxide co-treated with Tretinoin] results in decreased expression of MYC protein; [Genistein co-treated with Arsenic Trioxide] results in decreased expression of MYC protein; [NVP-BKM120 co-treated with Arsenic Trioxide] results in decreased expression of MYC mRNA; [ruxolitinib co-treated with Arsenic Trioxide] results in decreased expression of MYC mRNA; Acetylcysteine inhibits the reaction [[Arsenic Trioxide co-treated with Cisplatin] results in decreased expression of MYC protein]; Arsenic Trioxide inhibits the reaction [Lithium Chloride results in increased expression of MYC protein]; Arsenic Trioxide inhibits the reaction [MYC protein binds to PRDX3 protein]; Arsenic Trioxide inhibits the reaction [MYC protein results in increased activity of PRDX3 protein]; Arsenic Trioxide inhibits the reaction [SP1 protein binds to MYC promoter]; Arsenic Trioxide promotes the reaction [MSI1 protein results in increased expression of MYC protein]; Arsenic Trioxide promotes the reaction [Tretinoin results in decreased expression of MYC protein]; BCL2 protein inhibits the reaction [Arsenic Trioxide results in decreased expression of MYC mRNA]; CAB39L protein alternative form inhibits the reaction [Arsenic Trioxide results in decreased expression of MYC protein]; EIF2AK2 protein affects the reaction [Arsenic Trioxide promotes the reaction [MSI1 protein results in increased expression of MYC protein]]; EIF2AK2 protein affects the reaction [Arsenic Trioxide results in increased expression of MYC protein]; EIF2S1 protein affects the reaction [Arsenic Trioxide promotes the reaction [MSI1 protein results in increased expression of MYC protein]]; GH1 protein promotes the reaction [Arsenic Trioxide results in increased expression of MYC mRNA]; GRB10 protein promotes the reaction [[Arsenic Trioxide co-treated with apatinib] results in decreased expression of MYC protein]; MSI1 protein affects the reaction [Arsenic Trioxide results in increased expression of MYC protein]; RORB protein affects the reaction [Arsenic Trioxide affects the expression of MYC protein]; Tretinoin promotes the reaction [Arsenic Trioxide results in decreased expression of MYC protein]; VS-5584 promotes the reaction [Arsenic Trioxide results in decreased expression of MYC mRNA] Arsenic Trioxide results in increased expression of MYC mRNA; Arsenic Trioxide results in increased expression of MYC protein Arsenic Trioxide promotes the reaction [Berberine affects the localization of MYC protein]
|
CTD |
PMID:11714746 PMID:11775218 PMID:12903497 PMID:12903512 PMID:15283693 PMID:15761015 PMID:18294404 PMID:19408305 PMID:19769630 PMID:20953137 PMID:21078540 PMID:22944098 PMID:23851143 PMID:25174355 PMID:25335113 PMID:25436934 PMID:26046465 PMID:26966376 PMID:27039805 PMID:28565807 PMID:28901456 PMID:29059232 PMID:29355690 PMID:29486283 PMID:29574283 PMID:29944906 PMID:30012499 PMID:30093655 PMID:30145367 PMID:30316766 PMID:31539632 PMID:34413873 PMID:38179723 PMID:38797699 PMID:39223679 PMID:39716349 More...
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|
NCBI chr 7:95,483,105...95,488,031
Ensembl chr 7:95,483,105...95,488,028
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|
| G
|
Mycbp2
|
MYC binding protein 2
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of MYCBP2 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr15:86,352,061...86,590,126
Ensembl chr15:86,352,061...86,590,325
|
|
| G
|
Mycn
|
MYCN proto-oncogene, bHLH transcription factor
|
decreases expression increases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of MYCN mRNA; Arsenic Trioxide results in decreased expression of MYCN protein Arsenic Trioxide results in increased expression of MYCN mRNA
|
CTD |
PMID:12478894 PMID:20458559 PMID:24685274 PMID:38130211 |
|
NCBI chr 6:41,446,683...41,452,584
Ensembl chr 6:41,446,684...41,452,508
|
|
| G
|
Myd88
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MYD88, innate immune signal transduction adaptor
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of MYD88 mRNA
|
CTD |
PMID:17530438 |
|
NCBI chr 8:127,952,161...127,956,230
Ensembl chr 8:127,952,161...127,956,230
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|
| G
|
Myh10
|
myosin heavy chain 10
|
increases expression decreases expression
|
ISO
|
Arsenic Trioxide results in increased expression of MYH10 mRNA Arsenic Trioxide results in decreased expression of MYH10 mRNA
|
CTD |
PMID:20458559 PMID:26238599 |
|
NCBI chr10:53,891,955...54,024,032
Ensembl chr10:53,893,166...54,024,036
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|
| G
|
Myh6
|
myosin heavy chain 6
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of MYH6 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr15:32,388,102...32,413,663
Ensembl chr15:32,387,487...32,411,333
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|
| G
|
Myh7
|
myosin heavy chain 7
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of MYH7 mRNA
|
CTD |
PMID:35676786 |
|
NCBI chr15:32,416,525...32,439,851
Ensembl chr15:32,416,527...32,438,194
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|
| G
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Myh9
|
myosin, heavy chain 9
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of MYH9 protein
|
CTD |
PMID:25258189 |
|
NCBI chr 7:111,224,291...111,304,963
Ensembl chr 7:111,224,291...111,304,963
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| G
|
Myl4
|
myosin, light chain 4
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of MYL4 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr10:89,949,733...89,985,308
Ensembl chr10:89,949,404...89,985,308
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|
| G
|
Mylk
|
myosin light chain kinase
|
decreases expression increases expression multiple interactions
|
ISO
|
Arsenic Trioxide results in decreased expression of MYLK mRNA Arsenic Trioxide results in increased expression of MYLK mRNA; Arsenic Trioxide results in increased expression of MYLK protein 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Arsenic Trioxide results in increased expression of MYLK mRNA]
|
CTD |
PMID:26238599 PMID:32683294 |
|
NCBI chr11:79,288,243...79,535,450
Ensembl chr11:79,288,243...79,535,659
|
|
| G
|
Myo18a
|
myosin XVIIIa
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of MYO18A mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr10:63,152,303...63,253,543
Ensembl chr10:63,152,103...63,253,543
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|
| G
|
Myo1b
|
myosin Ib
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of MYO1B mRNA
|
CTD |
PMID:15070760 PMID:15761015 |
|
NCBI chr 9:57,182,059...57,344,335
Ensembl chr 9:57,181,987...57,344,328
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|
| G
|
Myo1e
|
myosin IE
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of MYO1E mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr 8:79,768,828...79,961,048
Ensembl chr 8:79,753,596...79,961,045
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|
| G
|
Myo5b
|
myosin Vb
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of MYO5B mRNA
|
CTD |
PMID:22521957 |
|
NCBI chr18:70,313,717...70,613,918
Ensembl chr18:70,311,990...70,613,918
|
|
| G
|
Myo5c
|
myosin VC
|
decreases response to substance
|
ISO
|
MYO5C protein results in decreased susceptibility to Arsenic Trioxide
|
CTD |
PMID:20707922 |
|
NCBI chr 8:84,870,031...84,946,996
Ensembl chr 8:84,870,043...84,946,996
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|
| G
|
Myo6
|
myosin VI
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of MYO6 mRNA
|
CTD |
PMID:17258074 |
|
NCBI chr 8:89,967,351...90,122,219
Ensembl chr 8:89,967,377...90,122,215
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|
| G
|
Myo9b
|
myosin IXb
|
multiple interactions decreases expression
|
ISO
|
[Tretinoin co-treated with Arsenic Trioxide] results in decreased expression of MYO9B protein Arsenic Trioxide results in decreased expression of MYO9B protein
|
CTD |
PMID:15894607 |
|
NCBI chr16:17,979,374...18,064,100
Ensembl chr16:17,979,439...18,064,332
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|
| G
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Myocd
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myocardin
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of MYOCD mRNA
|
CTD |
PMID:26705709 |
|
NCBI chr10:50,332,356...50,426,819
Ensembl chr10:50,332,356...50,426,819
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|
| G
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Myof
|
myoferlin
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of MYOF mRNA
|
CTD |
PMID:19128835 |
|
NCBI chr 1:245,086,109...245,234,768
Ensembl chr 1:245,086,109...245,234,768
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|
| G
|
Myom1
|
myomesin 1
|
decreases expression multiple interactions
|
ISO
|
Arsenic Trioxide results in decreased expression of MYOM1 protein [Tretinoin co-treated with Arsenic Trioxide] results in decreased expression of MYOM1 protein
|
CTD |
PMID:15894607 |
|
NCBI chr 9:118,362,547...118,485,954
Ensembl chr 9:118,362,621...118,485,952
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|
| G
|
Myt1l
|
myelin transcription factor 1-like
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of MYT1L mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 6:51,892,858...52,291,830
Ensembl chr 6:52,155,754...52,291,828
|
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| G
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Myzap
|
myocardial zonula adherens protein
|
multiple interactions increases expression
|
ISO
|
Metformin inhibits the reaction [Arsenic Trioxide results in increased expression of MYZAP mRNA]
|
CTD |
PMID:29095437 |
|
NCBI chr 8:81,036,599...81,123,933
Ensembl chr 8:81,036,601...81,123,810
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|
| G
|
N4bp1
|
Nedd4 binding protein 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of N4BP1 mRNA
|
CTD |
PMID:15761015 |
|
NCBI chr19:36,396,082...36,446,835
Ensembl chr19:36,396,324...36,446,835
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|
| G
|
N4bp2l1
|
NEDD4 binding protein 2-like 1
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of N4BP2L1 mRNA
|
CTD |
PMID:15761015 |
|
NCBI chr12:4,938,199...4,965,003
Ensembl chr12:4,927,142...4,963,045
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| G
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Naa20
|
N(alpha)-acetyltransferase 20, NatB catalytic subunit
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of NAA20 mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr 3:153,775,351...153,790,129
Ensembl chr 3:153,775,338...153,790,916
|
|
| G
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Naaa
|
N-acylethanolamine acid amidase
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of NAAA mRNA
|
CTD |
PMID:22521957 |
|
NCBI chr14:16,061,599...16,080,703
Ensembl chr14:16,061,583...16,080,702
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|
| G
|
Nab2
|
Ngfi-A binding protein 2
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of NAB2 mRNA
|
CTD |
PMID:15761015 PMID:20458559 |
|
NCBI chr 7:65,382,863...65,389,527
Ensembl chr 7:65,382,863...65,389,255
|
|
| G
|
Nabp1
|
nucleic acid binding protein 1
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to NABP1 protein]
|
CTD |
PMID:26598702 |
|
NCBI chr 9:57,570,326...57,625,926
Ensembl chr 9:57,618,505...57,626,052
|
|
| G
|
Naca
|
nascent polypeptide associated complex subunit alpha
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of NACA mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 7:1,053,474...1,066,606
Ensembl chr 7:1,054,338...1,066,605
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|
| G
|
Nadk2
|
NAD kinase 2, mitochondrial
|
affects expression
|
ISO
|
Arsenic Trioxide affects the expression of NADK2 mRNA
|
CTD |
PMID:35676786 |
|
NCBI chr 2:59,844,854...59,886,989
Ensembl chr 2:59,844,854...59,886,988
|
|
| G
|
Naglu
|
N-acetyl-alpha-glucosaminidase
|
multiple interactions decreases expression
|
ISO
|
Metformin inhibits the reaction [Arsenic Trioxide results in decreased expression of NAGLU mRNA]
|
CTD |
PMID:29095437 |
|
NCBI chr10:86,501,864...86,509,333
Ensembl chr10:86,501,836...86,509,315
|
|
| G
|
Naip5
|
NLR family, apoptosis inhibitory protein 5
|
decreases expression
|
EXP
|
Arsenic Trioxide results in decreased expression of NAIP5 mRNA
|
CTD |
PMID:19730151 |
|
NCBI chr 2:33,289,785...33,342,807
Ensembl chr 2:33,282,466...33,323,401
|
|
| G
|
Naip6
|
NLR family, apoptosis inhibitory protein 6
|
decreases expression
|
EXP
|
Arsenic Trioxide results in decreased expression of NAIP2 mRNA
|
CTD |
PMID:19730151 |
|
NCBI chr 2:33,241,520...33,293,184
Ensembl chr 2:33,241,521...33,276,859
|
|
| G
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Nampt
|
nicotinamide phosphoribosyltransferase
|
multiple interactions decreases expression
|
ISO
|
Arsenic Trioxide promotes the reaction [N-(4-(1-benzoylpiperidin-4-yl)butyl)-3-(pyridin-3-yl)acrylamide results in decreased expression of NAMPT mRNA]; N-(4-(1-benzoylpiperidin-4-yl)butyl)-3-(pyridin-3-yl)acrylamide promotes the reaction [Arsenic Trioxide results in decreased expression of NAMPT mRNA] Arsenic Trioxide results in decreased expression of NAMPT mRNA; Arsenic Trioxide results in decreased expression of NAMPT protein
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CTD |
PMID:28501332 PMID:39716349 |
|
NCBI chr 6:55,152,756...55,189,547
Ensembl chr 6:55,151,926...55,189,544
|
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| G
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Nanog
|
Nanog homeobox
|
increases cleavage decreases expression multiple interactions increases expression
|
ISO
|
Arsenic Trioxide results in increased cleavage of NANOG protein Arsenic Trioxide results in decreased expression of NANOG mRNA [Arsenic Trioxide co-treated with Tretinoin] results in decreased expression of NANOG protein; ICG 001 affects the reaction [RORB protein affects the reaction [Arsenic Trioxide results in decreased expression of NANOG protein]]; PTGS2 protein affects the reaction [Arsenic Trioxide results in increased expression of NANOG protein]; RORB protein affects the reaction [Arsenic Trioxide results in decreased expression of NANOG protein]; SOX2 protein affects the reaction [Arsenic Trioxide results in increased expression of NANOG protein]; SOX2 protein affects the reaction [PTGS2 protein affects the reaction [Arsenic Trioxide results in increased expression of NANOG protein]] Arsenic Trioxide results in increased expression of NANOG mRNA; Arsenic Trioxide results in increased expression of NANOG protein Arsenic Trioxide results in decreased expression of NANOG mRNA; Arsenic Trioxide results in decreased expression of NANOG protein
|
CTD |
PMID:29396848 PMID:29767511 PMID:30093655 PMID:33634982 PMID:38797699 |
|
NCBI chr 4:157,615,687...157,623,061
Ensembl chr 4:157,615,687...157,623,061
|
|
| G
|
Nanp
|
N-acetylneuraminic acid phosphatase
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to NANP protein]
|
CTD |
PMID:26598702 |
|
NCBI chr 3:160,289,269...160,302,001
Ensembl chr 3:160,288,830...160,302,002
|
|
| G
|
Nans
|
N-acetylneuraminate synthase
|
decreases expression multiple interactions increases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of NANS protein Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to NANS protein] Arsenic Trioxide results in increased expression of NANS mRNA
|
CTD |
PMID:19364129 PMID:25419056 PMID:26598702 PMID:39716349 |
|
NCBI chr 5:65,575,970...65,593,164
Ensembl chr 5:65,576,015...65,610,547
|
|
| G
|
Nap1l1
|
nucleosome assembly protein 1-like 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of NAP1L1 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 7:48,819,464...48,844,108
Ensembl chr 7:48,819,477...48,844,104
|
|
| G
|
Napb
|
NSF attachment protein beta
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to NAPB protein]
|
CTD |
PMID:26598702 |
|
NCBI chr 3:156,585,394...156,632,418
Ensembl chr 3:156,585,394...156,632,418
|
|
| G
|
Napg
|
NSF attachment protein gamma
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to NAPG protein]
|
CTD |
PMID:26598702 |
|
NCBI chr18:58,710,702...58,729,450
Ensembl chr18:58,708,655...58,729,450
|
|
| G
|
Nasp
|
nuclear autoantigenic sperm protein
|
increases response to substance
|
ISO
|
NASP protein results in increased susceptibility to Arsenic Trioxide
|
CTD |
PMID:20707922 |
|
NCBI chr 5:135,294,599...135,319,992
Ensembl chr 5:135,294,032...135,319,591
|
|
| G
|
Nav1
|
neuron navigator 1
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of NAV1 mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr13:49,418,755...49,671,117
Ensembl chr13:49,418,755...49,671,004
|
|
| G
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Nav3
|
neuron navigator 3
|
increases expression decreases expression
|
ISO
|
Arsenic Trioxide results in increased expression of NAV3 mRNA Arsenic Trioxide results in decreased expression of NAV3 mRNA
|
CTD |
PMID:15761015 PMID:22521957 |
|
NCBI chr 7:46,938,577...47,726,839
Ensembl chr 7:46,940,670...47,504,893
|
|
| G
|
Nbl1
|
NBL1, DAN family BMP antagonist
|
multiple interactions
|
ISO
|
[Arsenic Trioxide co-treated with apatinib] results in decreased expression of NBL1 mRNA
|
CTD |
PMID:39223679 |
|
NCBI chr 5:156,601,986...156,613,182
Ensembl chr 5:156,601,986...156,613,186
|
|
| G
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Nbn
|
nibrin
|
increases expression
|
ISO EXP
|
Arsenic Trioxide results in increased expression of NBN mRNA Arsenic Trioxide results in increased expression of NBN protein
|
CTD |
PMID:17530438 PMID:23337567 |
|
NCBI chr 5:34,256,678...34,291,163
Ensembl chr 5:34,256,627...34,291,162
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| G
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Ncam2
|
neural cell adhesion molecule 2
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of NCAM2 mRNA
|
CTD |
PMID:26705709 |
|
NCBI chr11:33,591,748...34,078,788
Ensembl chr11:33,591,713...34,078,788
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| G
|
Ncaph
|
non-SMC condensin I complex, subunit H
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of NCAPH mRNA
|
CTD |
PMID:19128835 |
|
NCBI chr 3:134,825,271...134,852,502
Ensembl chr 3:134,825,271...134,852,502
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| G
|
Nceh1
|
neutral cholesterol ester hydrolase 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of NCEH1 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 2:112,003,677...112,064,274
Ensembl chr 2:112,003,502...112,064,272
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| G
|
Ncf1
|
neutrophil cytosolic factor 1
|
increases expression multiple interactions
|
ISO
|
Arsenic Trioxide results in increased expression of NCF1 protein ATF4 protein promotes the reaction [Arsenic Trioxide results in increased expression of NCF1 protein] Arsenic Trioxide results in increased expression of NCF1 mRNA; Arsenic Trioxide results in increased expression of NCF1 protein 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Arsenic Trioxide promotes the reaction [Tretinoin results in increased expression of NCF1 protein]]; acetovanillone inhibits the reaction [Arsenic Trioxide affects the localization of NCF1 protein]; Arsenic Trioxide promotes the reaction [Tretinoin results in increased expression of NCF1 protein]; Arsenic Trioxide results in increased phosphorylation of and affects the localization of NCF1 protein; SB 203580 inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of and affects the localization of NCF1 protein]; Y 27632 inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of and affects the localization of NCF1 protein]
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CTD |
PMID:15070760 PMID:15761015 PMID:18424721 PMID:20615082 PMID:27638049 |
|
NCBI chr12:28,121,816...28,131,080
Ensembl chr12:28,121,366...28,131,079
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| G
|
Ncf2
|
neutrophil cytosolic factor 2
|
affects localization multiple interactions increases expression
|
ISO
|
Arsenic Trioxide affects the localization of NCF2 protein NCF2 mutant form inhibits the reaction [Arsenic Trioxide results in increased abundance of Reactive Oxygen Species]; NCF2 mutant form inhibits the reaction [Arsenic Trioxide results in increased cleavage of PARP1 protein]; NCF2 mutant form inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of EGFR protein] Arsenic Trioxide results in increased expression of NCF2 protein ATF4 protein promotes the reaction [Arsenic Trioxide results in increased expression of NCF2 protein] Arsenic Trioxide results in increased expression of NCF2 mRNA; Arsenic Trioxide results in increased expression of NCF2 protein
|
CTD |
PMID:15070760 PMID:18424721 PMID:22532027 PMID:27638049 |
|
NCBI chr13:67,505,492...67,536,015
Ensembl chr13:67,505,375...67,536,149
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| G
|
Nckap1
|
NCK-associated protein 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of NCKAP1 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 3:85,824,333...85,898,748
Ensembl chr 3:85,824,336...85,898,797
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| G
|
Nckipsd
|
NCK interacting protein with SH3 domain
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of NCKIPSD mRNA
|
CTD |
PMID:27829220 |
|
NCBI chr 8:118,390,121...118,401,121
Ensembl chr 8:118,390,159...118,401,118
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|
| G
|
Ncl
|
nucleolin
|
multiple interactions
|
ISO
|
[Tretinoin co-treated with Arsenic Trioxide] results in increased expression of NCL mRNA
|
CTD |
PMID:15894607 |
|
NCBI chr 9:94,447,559...94,456,083
Ensembl chr 9:94,446,682...94,456,083
|
|
| G
|
Ncmap
|
noncompact myelin associated protein
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of NCMAP mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr 5:152,893,173...152,921,175
Ensembl chr 5:152,894,316...152,902,414
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|
| G
|
Ncoa2
|
nuclear receptor coactivator 2
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [Metribolone promotes the reaction [NCOA2 protein binds to KLK3 promoter]]
|
CTD |
PMID:19131511 |
|
NCBI chr 5:10,618,712...10,852,776
Ensembl chr 5:10,618,722...10,852,776
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|
| G
|
Ncoa4
|
nuclear receptor coactivator 4
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of NCOA4 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr16:7,395,502...7,415,846
Ensembl chr16:7,401,802...7,415,840
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|
| G
|
Ncoa7
|
nuclear receptor coactivator 7
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of NCOA7 mRNA
|
CTD |
PMID:22521957 PMID:24356939 |
|
NCBI chr 1:28,674,614...28,835,891
Ensembl chr 1:28,675,426...28,835,886
|
|
| G
|
Ndc80
|
NDC80 kinetochore complex component
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of NDC80 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 9:118,853,806...118,887,582
Ensembl chr 9:118,853,806...118,887,568
|
|
| G
|
Ndel1
|
nudE neurodevelopment protein 1-like 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of NDEL1 mRNA
|
CTD |
PMID:35676786 |
|
NCBI chr10:54,001,435...54,080,909
Ensembl chr10:54,016,149...54,062,375
|
|
| G
|
Ndor1
|
NADPH dependent diflavin oxidoreductase 1
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to NDOR1 protein]
|
CTD |
PMID:26598702 |
|
NCBI chr 3:28,460,787...28,469,018
Ensembl chr 3:28,460,797...28,469,018
|
|
| G
|
Ndp
|
norrin cystine knot growth factor NDP
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of NDP mRNA
|
CTD |
PMID:26705709 |
|
NCBI chr X:8,379,569...8,404,019
Ensembl chr X:8,379,569...8,406,802
|
|
| G
|
Ndrg1
|
N-myc downstream regulated 1
|
multiple interactions increases expression
|
ISO
|
[Arsenic Trioxide co-treated with Tretinoin] results in decreased expression of NDRG1 mRNA; [Arsenic Trioxide co-treated with Tretinoin] results in decreased expression of NDRG1 protein; [Tretinoin co-treated with Arsenic Trioxide] results in increased expression of NDRG1 mRNA Arsenic Trioxide results in increased expression of NDRG1 mRNA
|
CTD |
PMID:15894607 PMID:21575456 PMID:39716349 |
|
NCBI chr 7:100,573,526...100,614,902
Ensembl chr 7:100,573,523...100,614,913
|
|
| G
|
Ndrg3
|
NDRG family member 3
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of NDRG3 mRNA
|
CTD |
PMID:35676786 |
|
NCBI chr 3:166,007,556...166,070,981
Ensembl chr 3:165,890,091...166,049,887
|
|
| G
|
Ndrg4
|
NDRG family member 4
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of NDRG4 mRNA
|
CTD |
PMID:22521957 |
|
NCBI chr19:9,357,470...9,393,465
Ensembl chr19:9,357,470...9,392,972
|
|
| G
|
Ndst1
|
N-deacetylase and N-sulfotransferase 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of NDST1 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr18:56,407,308...56,470,007
Ensembl chr18:56,411,200...56,448,612
|
|
| G
|
Ndst3
|
N-deacetylase and N-sulfotransferase 3
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of NDST3 mRNA
|
CTD |
PMID:26705709 |
|
NCBI chr 2:214,386,804...214,552,739
Ensembl chr 2:214,389,447...214,539,164
|
|
| G
|
Ndufa10
|
NADH:ubiquinone oxidoreductase subunit A10
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of NDUFA10 mRNA
|
CTD |
PMID:22521957 |
|
NCBI chr 9:100,454,498...100,490,023
Ensembl chr 9:100,437,379...100,489,264
|
|
| G
|
Ndufa12
|
NADH:ubiquinone oxidoreductase subunit A12
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of NDUFA12 protein Arsenic Trioxide results in decreased expression of NDUFA12 mRNA
|
CTD |
PMID:19422848 PMID:25419056 |
|
NCBI chr 7:30,658,316...30,685,302
Ensembl chr 7:30,658,322...30,686,300
|
|
| G
|
Ndufa4
|
Ndufa4, mitochondrial complex associated
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of COXFA4 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 4:40,968,391...40,975,559
Ensembl chr 4:40,968,391...40,975,559
|
|
| G
|
Ndufa9
|
NADH:ubiquinone oxidoreductase subunit A9
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of NDUFA9 mRNA
|
CTD |
PMID:22521957 |
|
NCBI chr 4:161,345,398...161,374,188
Ensembl chr 4:161,345,400...161,375,025
|
|
| G
|
Ndufab1
|
NADH:ubiquinone oxidoreductase subunit AB1
|
increases expression decreases expression
|
ISO
|
Arsenic Trioxide results in increased expression of NDUFAB1 mRNA Arsenic Trioxide results in decreased expression of NDUFAB1 mRNA
|
CTD |
PMID:19422848 PMID:22521957 PMID:29633893 |
|
NCBI chr 1:186,075,933...186,091,843
Ensembl chr 1:186,057,113...186,089,373
|
|
| G
|
Ndufaf1
|
NADH:ubiquinone oxidoreductase complex assembly factor 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of NDUFAF1 mRNA
|
CTD |
PMID:22521957 |
|
NCBI chr 3:127,089,893...127,104,357
Ensembl chr 3:127,093,659...127,104,020
|
|
| G
|
Ndufb2
|
NADH:ubiquinone oxidoreductase subunit B2
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of NDUFB2 mRNA
|
CTD |
PMID:19422848 |
|
NCBI chr 4:69,334,307...69,341,394
Ensembl chr 4:69,334,307...69,340,136 Ensembl chr15:69,334,307...69,340,136
|
|
| G
|
Ndufc1
|
NADH:ubiquinone oxidoreductase subunit C1
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of NDUFC1 mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr 2:137,597,944...137,601,819
Ensembl chr 2:137,600,156...137,601,735
|
|
| G
|
Ndufs1
|
NADH:ubiquinone oxidoreductase core subunit S1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of NDUFS1 mRNA
|
CTD |
PMID:22521957 |
|
NCBI chr 9:72,040,286...72,073,605
Ensembl chr 9:72,040,090...72,073,605
|
|
| G
|
Ndufs2
|
NADH:ubiquinone oxidoreductase core subunit S2
|
increases expression decreases expression
|
ISO
|
Arsenic Trioxide results in increased expression of NDUFS2 mRNA Arsenic Trioxide results in decreased expression of NDUFS2 mRNA
|
CTD |
PMID:22521957 PMID:35676786 PMID:39716349 |
|
NCBI chr13:86,186,867...86,203,914
Ensembl chr13:86,186,870...86,203,608
|
|
| G
|
Ndufs8
|
NADH:ubiquinone oxidoreductase core subunit S8
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of NDUFS8 mRNA
|
CTD |
PMID:24831965 |
|
NCBI chr 1:210,569,823...210,573,707
Ensembl chr 1:210,569,824...210,572,971
|
|
| G
|
Neat1
|
nuclear paraspeckle assembly transcript 1
|
decreases expression multiple interactions increases expression
|
EXP ISO
|
Arsenic Trioxide results in decreased expression of NEAT1 mRNA NEAT1 mRNA affects the reaction [Arsenic Trioxide affects the expression of IL1B mRNA]; NEAT1 mRNA affects the reaction [Arsenic Trioxide affects the expression of IL1B protein]; NEAT1 mRNA affects the reaction [Arsenic Trioxide affects the expression of IL6 mRNA]; NEAT1 mRNA affects the reaction [Arsenic Trioxide affects the expression of IL6 protein]; NEAT1 mRNA affects the reaction [Arsenic Trioxide affects the expression of TNF mRNA]; NEAT1 mRNA affects the reaction [Arsenic Trioxide affects the expression of TNF protein] Arsenic Trioxide results in increased expression of NEAT1 mRNA
|
CTD |
PMID:32096187 PMID:39716349 |
|
NCBI chr 1:212,507,512...212,568,055
|
|
| G
|
Necab2
|
N-terminal EF-hand calcium binding protein 2
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of NECAB2 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr19:64,409,627...64,436,371
Ensembl chr19:64,409,751...64,436,369
|
|
| G
|
Nectin1
|
nectin cell adhesion molecule 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of PVRL1 mRNA Arsenic Trioxide results in increased expression of NECTIN1 mRNA
|
CTD |
PMID:29633893 PMID:39716349 |
|
NCBI chr 8:52,998,662...53,061,745
Ensembl chr 8:52,998,662...53,086,664
|
|
| G
|
Nectin3
|
nectin cell adhesion molecule 3
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of NECTIN3 mRNA
|
CTD |
PMID:22521957 |
|
NCBI chr11:67,825,296...67,931,999
Ensembl chr11:67,827,137...67,871,383
|
|
| G
|
Nedd1
|
NEDD1 gamma-tubulin ring complex targeting factor
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of NEDD1 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 7:29,120,200...29,161,634
Ensembl chr 7:29,120,200...29,161,634
|
|
| G
|
Nedd8
|
NEDD8 ubiquitin like modifier
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of NEDD8 protein
|
CTD |
PMID:19364129 |
|
NCBI chr15:33,123,505...33,135,522
Ensembl chr15:33,123,505...33,135,522
|
|
| G
|
Nefm
|
neurofilament medium chain
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of NEFM protein
|
CTD |
PMID:35467087 |
|
NCBI chr15:46,535,857...46,541,161
Ensembl chr15:46,535,517...46,541,163
|
|
| G
|
Nek1
|
NIMA-related kinase 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of NEK1 mRNA
|
CTD |
PMID:22521957 |
|
NCBI chr16:34,009,092...34,137,418
Ensembl chr16:34,009,094...34,128,576
|
|
| G
|
Nek7
|
NIMA-related kinase 7
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of NEK7 mRNA
|
CTD |
PMID:22521957 |
|
NCBI chr13:52,573,730...52,700,869
Ensembl chr13:52,573,730...52,700,823
|
|
| G
|
Nenf
|
neudesin neurotrophic factor
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of NENF mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr13:105,419,113...105,425,911
Ensembl chr13:105,419,113...105,426,091
|
|
| G
|
Neo1
|
neogenin 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of NEO1 mRNA
|
CTD |
PMID:27829220 |
|
NCBI chr 8:68,169,711...68,322,158
Ensembl chr 8:68,169,716...68,322,152
|
|
| G
|
Nes
|
nestin
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of NES mRNA
|
CTD |
PMID:22521957 |
|
NCBI chr 2:175,735,715...175,745,631
Ensembl chr 2:175,736,551...175,746,228
|
|
| G
|
Neto2
|
neuropilin and tolloid like 2
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of NETO2 mRNA
|
CTD |
PMID:25258189 |
|
NCBI chr19:37,517,518...37,588,961
Ensembl chr19:37,517,587...37,591,413
|
|
| G
|
Neu2
|
neuraminidase 2
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of NEU2 mRNA
|
CTD |
PMID:35676786 |
|
NCBI chr 9:95,666,338...95,715,209
Ensembl chr 9:95,696,507...95,715,208
|
|
| G
|
Neu3
|
neuraminidase 3
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of NEU3 mRNA
|
CTD |
PMID:15070760 |
|
NCBI chr 1:163,549,834...163,560,997
Ensembl chr 1:163,549,738...163,561,049
|
|
| G
|
Nf2
|
NF2, moesin-ezrin-radixin like (MERLIN) tumor suppressor
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of NF2 mRNA
|
CTD |
PMID:11940349 PMID:25258189 |
|
NCBI chr14:83,850,894...83,934,263
Ensembl chr14:83,850,894...83,934,151
|
|
| G
|
Nfatc1
|
nuclear factor of activated T-cells 1
|
increases expression multiple interactions
|
EXP
|
Arsenic Trioxide results in increased expression of NFATC1 mRNA; Arsenic Trioxide results in increased expression of NFATC1 protein Phloretin inhibits the reaction [Arsenic Trioxide results in increased expression of NFATC1 mRNA]; Phloretin inhibits the reaction [Arsenic Trioxide results in increased expression of NFATC1 protein]
|
CTD |
PMID:34037972 |
|
NCBI chr18:76,321,386...76,430,997
Ensembl chr18:76,321,386...76,430,990
|
|
| G
|
Nfatc3
|
nuclear factor of activated T-cells 3
|
decreases expression affects expression
|
ISO
|
Arsenic Trioxide results in decreased expression of NFATC3 mRNA Arsenic Trioxide affects the expression of NFATC3 mRNA
|
CTD |
PMID:29633893 PMID:39716349 |
|
NCBI chr19:50,870,464...50,944,992
Ensembl chr19:50,870,489...50,944,992
|
|
| G
|
Nfe2l1
|
NFE2 like bZIP transcription factor 1
|
multiple interactions
|
ISO
|
Arsenic Trioxide results in increased expression of and results in increased activity of NFE2L1 protein
|
CTD |
PMID:16487037 |
|
NCBI chr10:82,296,824...82,309,472
Ensembl chr10:82,292,508...82,309,375
|
|
| G
|
Nfe2l2
|
NFE2 like bZIP transcription factor 2
|
multiple interactions affects response to substance increases expression decreases expression decreases response to substance affects localization
|
EXP ISO
|
Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased expression of and affects the localization of NFE2L2 protein]; alpha-Tocopherol inhibits the reaction [Arsenic Trioxide results in decreased expression of NFE2L2 mRNA]; Arsenic Trioxide affects the expression of and affects the phosphorylation of NFE2L2 protein; Arsenic Trioxide results in increased expression of and affects the localization of NFE2L2 protein; Arsenic Trioxide results in increased phosphorylation of and affects the localization of NFE2L2 protein; Ascorbic Acid inhibits the reaction [Arsenic Trioxide results in decreased expression of NFE2L2 mRNA]; Buthionine Sulfoximine promotes the reaction [Arsenic Trioxide results in increased expression of and affects the localization of NFE2L2 protein]; crocin inhibits the reaction [Arsenic Trioxide results in decreased expression of NFE2L2 protein]; eriodictyol promotes the reaction [Arsenic Trioxide results in increased expression of NFE2L2 mRNA]; eriodictyol promotes the reaction [Arsenic Trioxide results in increased expression of NFE2L2 protein]; Nicorandil affects the reaction [Arsenic Trioxide affects the expression of and affects the phosphorylation of NFE2L2 protein]; oxymatrine promotes the reaction [Arsenic Trioxide results in increased expression of NFE2L2 protein]; Resveratrol inhibits the reaction [Arsenic Trioxide results in decreased expression of NFE2L2 mRNA] NFE2L2 protein affects the susceptibility to Arsenic Trioxide Arsenic Trioxide results in increased expression of NFE2L2 mRNA; Arsenic Trioxide results in increased expression of NFE2L2 protein Arsenic Trioxide results in decreased expression of NFE2L2 mRNA; Arsenic Trioxide results in decreased expression of NFE2L2 protein 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt inhibits the reaction [Arsenic Trioxide results in increased expression of NFE2L2 mRNA]; 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt inhibits the reaction [Arsenic Trioxide results in increased expression of NFE2L2 protein]; 18alpha,20beta-hydroxy-11-oxo-norolean-12-en-3beta-yl-2-O-beta-D-glucopyranurosyl-alpha-D-glucopyranosiduronate magnesium tetrahydrate inhibits the reaction [Arsenic Trioxide results in decreased expression of NFE2L2 protein]; [Arsenic Trioxide co-treated with Grape Seed Proanthocyanidins] results in increased expression of NFE2L2 mRNA; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in decreased expression of NFE2L2 protein]; Arsenic Trioxide promotes the reaction [Lutein results in increased expression of NFE2L2 mRNA]; Arsenic Trioxide promotes the reaction [Lutein results in increased expression of NFE2L2 protein]; Lutein promotes the reaction [Arsenic Trioxide results in increased expression of NFE2L2 mRNA]; Lutein promotes the reaction [Arsenic Trioxide results in increased expression of NFE2L2 protein]; NFE2L2 protein affects the reaction [Arsenic Trioxide results in decreased expression of TNF protein]; NFE2L2 protein affects the reaction [Arsenic Trioxide results in increased expression of GCLC mRNA]; NFE2L2 protein affects the reaction [Arsenic Trioxide results in increased expression of HMOX1 mRNA]; NFE2L2 protein affects the reaction [Arsenic Trioxide results in increased expression of NQO1 mRNA]; NFE2L2 protein promotes the reaction [Arsenic Trioxide results in increased expression of NQO1 protein]; SB 203580 inhibits the reaction [Arsenic Trioxide results in increased expression of NFE2L2 mRNA]; Thioctic Acid inhibits the reaction [Arsenic Trioxide results in increased expression of NFE2L2 mRNA]; Thioctic Acid inhibits the reaction [Arsenic Trioxide results in increased expression of NFE2L2 protein] NFE2L2 mRNA results in decreased susceptibility to Arsenic Trioxide; NFE2L2 protein results in decreased susceptibility to Arsenic Trioxide Arsenic Trioxide affects the localization of NFE2L2 protein [Arsenic Trioxide results in increased abundance of Arsenic] which results in increased expression of and affects the localization of NFE2L2 protein; [Arsenic Trioxide results in increased abundance of Arsenic] which results in increased expression of NFE2L2 mRNA; [Arsenic Trioxide results in increased abundance of Arsenic] which results in increased expression of NFE2L2 protein; [Resveratrol co-treated with Arsenic Trioxide] results in increased expression of NFE2L2 protein; [Tretinoin co-treated with Arsenic Trioxide] results in increased expression of NFE2L2 mRNA; Acetylcysteine inhibits the reaction [Arsenic Trioxide affects the localization of NFE2L2 protein]; allicin inhibits the reaction [Arsenic Trioxide results in decreased expression of NFE2L2 protein]; Arsenic Trioxide promotes the reaction [NFE2L2 protein binds to VMP1 gene]; Arsenic Trioxide promotes the reaction [Resveratrol results in increased expression of NFE2L2 protein]; Arsenic Trioxide results in increased expression of and affects the localization of NFE2L2 protein; NFE2L2 mRNA promotes the reaction [Ethionamide results in increased susceptibility to Arsenic Trioxide]; NFE2L2 promotes the reaction [Arsenic Trioxide results in increased expression of MIR21 protein]; NFE2L2 protein affects the reaction [Arsenic Trioxide results in decreased expression of ACTA2 protein]; NFE2L2 protein affects the reaction [Arsenic Trioxide results in increased expression of HMOX1 mRNA]; NFE2L2 protein inhibits the reaction [Arsenic Trioxide results in increased abundance of Reactive Oxygen Species]; NFE2L2 protein promotes the reaction [Arsenic Trioxide results in increased expression of HMOX1 protein]; NFE2L2 protein promotes the reaction [Arsenic Trioxide results in increased expression of KEAP1 protein]; NFE2L2 protein promotes the reaction [Arsenic Trioxide results in increased expression of NQO1 protein]; NFE2L2 protein promotes the reaction [Arsenic Trioxide results in increased expression of PPARG mRNA]; NFE2L2 protein promotes the reaction [Rosiglitazone results in increased susceptibility to Arsenic Trioxide]; NFE2L2 protein promotes the reaction [Troglitazone results in increased susceptibility to Arsenic Trioxide]; Resveratrol promotes the reaction [Arsenic Trioxide results in increased expression of NFE2L2 protein]; TGM2 protein affects the reaction [[Tretinoin co-treated with Arsenic Trioxide] results in increased expression of NFE2L2 mRNA]; Tretinoin inhibits the reaction [Arsenic Trioxide affects the localization of NFE2L2 protein]
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CTD |
PMID:19350554 PMID:20707922 PMID:21327864 PMID:22155346 PMID:22488045 PMID:22684020 PMID:24157283 PMID:24327821 PMID:24634002 PMID:24801890 PMID:25003661 PMID:25341331 PMID:25815309 PMID:25966753 PMID:26187899 PMID:26283888 PMID:26708503 PMID:26772155 PMID:27561292 PMID:27592447 PMID:27713174 PMID:28978146 PMID:29049341 PMID:29223816 PMID:29297235 PMID:29876539 PMID:29986281 PMID:30317545 PMID:31258454 PMID:32920515 PMID:33434570 PMID:33603344 PMID:33846815 PMID:35276128 PMID:37446117 PMID:38295932 PMID:38741475 PMID:39152142 PMID:39630573 More...
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NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:81,001,529...81,029,090
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| G
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Nfia
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nuclear factor I/A
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decreases expression increases expression
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ISO
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Arsenic Trioxide results in decreased expression of NFIA mRNA Arsenic Trioxide results in increased expression of NFIA mRNA
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CTD |
PMID:19128835 PMID:26705709 |
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NCBI chr 5:117,359,006...117,897,391
Ensembl chr 5:117,359,077...117,891,395
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| G
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Nfkb1
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nuclear factor kappa B subunit 1
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affects localization increases expression multiple interactions decreases expression decreases activity
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ISO
|
Arsenic Trioxide affects the localization of NFKB1 protein Arsenic Trioxide results in increased expression of NFKB1 mRNA [BIBR 1532 co-treated with Arsenic Trioxide] affects the expression of NFKB1 mRNA; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in decreased activity of NFKB1 protein]; Arsenic Trioxide inhibits the reaction [RELA protein binds to NFKB1 protein]; JAK1 protein inhibits the reaction [Arsenic Trioxide results in decreased expression of NFKB1 protein]; STAT3 protein inhibits the reaction [Arsenic Trioxide results in decreased expression of NFKB1 protein] Arsenic Trioxide results in decreased expression of NFKB1 mRNA; Arsenic Trioxide results in decreased expression of NFKB1 protein
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CTD |
PMID:15073043 PMID:15314284 PMID:18349030 PMID:18922898 PMID:20458559 PMID:20471514 PMID:25410152 PMID:30333888 PMID:32645343 PMID:33634982 More...
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NCBI chr 2:226,689,745...226,805,897
Ensembl chr 2:226,689,745...226,783,088
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| G
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Nfkb2
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nuclear factor kappa B subunit 2
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increases expression decreases expression multiple interactions
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ISO
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Arsenic Trioxide results in increased expression of NFKB2 mRNA Arsenic Trioxide results in decreased expression of NFKB2 protein Arsenic Trioxide inhibits the reaction [Homoharringtonine results in increased expression of NFKB2 protein]
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CTD |
PMID:18349030 PMID:29633893 PMID:31307525 PMID:33634982 |
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NCBI chr 1:255,106,010...255,114,649
Ensembl chr 1:255,107,374...255,114,637
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| G
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Nfkbia
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NFKB inhibitor alpha
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multiple interactions decreases expression increases expression decreases phosphorylation decreases degradation
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ISO EXP
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[[Sulindac co-treated with Arsenic Trioxide] results in decreased phosphorylation of and results in decreased degradation of NFKBIA protein] which affects the localization of RELA protein; [Arsenic Trioxide co-treated with Tetradecanoylphorbol Acetate] results in decreased degradation of NFKBIA protein; [BIBR 1532 co-treated with Arsenic Trioxide] affects the expression of NFKBIA mRNA; [Bortezomib co-treated with Arsenic Trioxide] affects the expression of NFKBIA protein; [Sulindac co-treated with Arsenic Trioxide] results in decreased phosphorylation of and results in decreased degradation of NFKBIA protein; Arsenic Trioxide inhibits the reaction [CXCL12 protein results in increased phosphorylation of and results in increased degradation of NFKBIA protein]; Arsenic Trioxide promotes the reaction [Aprepitant results in decreased phosphorylation of NFKBIA protein]; Arsenic Trioxide promotes the reaction [VS-5584 results in decreased phosphorylation of NFKBIA protein]; Arsenic Trioxide results in decreased degradation of and results in increased stability of NFKBIA protein; NFKBIA protein inhibits the reaction [Arsenic Trioxide results in increased expression of FAS protein] Arsenic Trioxide results in increased phosphorylation of and results in increased degradation of NFKBIA protein; Febuxostat inhibits the reaction [Arsenic Trioxide results in decreased expression of NFKBIA protein] Arsenic Trioxide results in decreased expression of NFKBIA; Arsenic Trioxide results in decreased expression of NFKBIA mRNA Arsenic Trioxide results in increased expression of NFKBIA mRNA; Arsenic Trioxide results in increased expression of NFKBIA protein Arsenic Trioxide results in decreased phosphorylation of NFKBIA protein Arsenic Trioxide results in decreased degradation of NFKBIA protein Arsenic Trioxide inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in decreased expression of NFKBIA protein]
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CTD |
PMID:11739184 PMID:12560223 PMID:15382040 PMID:15476326 PMID:15547942 PMID:16174796 PMID:18575716 PMID:18718063 PMID:20458559 PMID:20471514 PMID:20534739 PMID:25047463 PMID:27664319 PMID:29574283 PMID:30145367 PMID:30612216 PMID:32645343 PMID:37689273 PMID:38237221 More...
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NCBI chr 6:78,593,844...78,597,307
Ensembl chr 6:78,593,847...78,597,072
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| G
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Nfkbib
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NFKB inhibitor beta
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decreases expression increases expression
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ISO
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Arsenic Trioxide results in decreased expression of NFKBIB mRNA Arsenic Trioxide results in increased expression of NFKBIB mRNA
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CTD |
PMID:19769630 PMID:20471514 |
|
NCBI chr 1:93,173,817...93,181,387
Ensembl chr 1:93,173,820...93,326,366
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| G
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Nfkbie
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NFKB inhibitor epsilon
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multiple interactions decreases expression
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ISO
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Arsenic Trioxide results in decreased degradation of and results in increased stability of NFKBIE protein; Bortezomib inhibits the reaction [Arsenic Trioxide results in decreased expression of NFKBIE mRNA]
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CTD |
PMID:12560223 PMID:20471514 |
|
NCBI chr 9:22,941,037...22,947,872
Ensembl chr 9:22,941,040...22,947,872
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| G
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Ngfr
|
nerve growth factor receptor
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multiple interactions increases expression
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ISO
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Arsenic Trioxide promotes the reaction [Drugs, Chinese Herbal results in increased expression of TNFRSF10B protein]; Drugs, Chinese Herbal promotes the reaction [Arsenic Trioxide results in increased expression of TNFRSF10B protein]
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CTD |
PMID:28587418 |
|
NCBI chr10:81,012,077...81,030,305
Ensembl chr10:81,012,089...81,030,305
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| G
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Ngrn
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neugrin, neurite outgrowth associated
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increases expression
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ISO
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Arsenic Trioxide results in increased expression of NGRN mRNA
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CTD |
PMID:20458559 |
|
NCBI chr 1:143,622,494...143,628,609
Ensembl chr 1:143,622,731...143,628,609
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| G
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Nherf1
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NHERF family PDZ scaffold protein 1
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increases expression
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ISO
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Arsenic Trioxide results in increased expression of NHERF1 protein
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CTD |
PMID:25419056 |
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NCBI chr10:100,902,165...100,919,265
Ensembl chr10:100,901,227...100,919,579
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| G
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Nhsl3
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NHS like 3
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increases expression
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ISO
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Arsenic Trioxide results in increased expression of NHSL3 mRNA
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CTD |
PMID:20458559 |
|
NCBI chr 5:146,848,747...146,877,504
Ensembl chr 5:146,848,747...146,877,504
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| G
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Niban1
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niban apoptosis regulator 1
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increases expression decreases expression
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ISO
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Arsenic Trioxide results in increased expression of NIBAN1 protein Arsenic Trioxide results in decreased expression of NIBAN1 mRNA
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CTD |
PMID:30093655 PMID:35676786 |
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NCBI chr13:66,224,219...66,377,728
Ensembl chr13:66,224,021...66,377,724
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| G
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Niban2
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niban apoptosis regulator 2
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decreases expression
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ISO
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Arsenic Trioxide results in decreased expression of NIBAN2 mRNA
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CTD |
PMID:35676786 |
|
NCBI chr 3:36,572,356...36,621,968
Ensembl chr 3:36,572,377...36,621,967
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| G
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Nifk
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nucleolar protein interacting with the FHA domain of MKI67
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increases expression
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ISO
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Arsenic Trioxide results in increased expression of NIFK mRNA
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CTD |
PMID:14703492 |
|
NCBI chr13:31,946,119...31,955,950
Ensembl chr13:31,946,108...31,959,561
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| G
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Ninj2
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ninjurin 2
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decreases expression
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ISO
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Arsenic Trioxide results in decreased expression of NINJ2 mRNA
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CTD |
PMID:26705709 |
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NCBI chr 4:154,978,660...155,080,860
Ensembl chr 4:155,073,295...155,080,860
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| G
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Nipal3
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NIPA-like domain containing 3
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increases expression
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ISO
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Arsenic Trioxide results in increased expression of NIPAL3 mRNA
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CTD |
PMID:26705709 |
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NCBI chr 5:152,970,934...153,010,006
Ensembl chr 5:152,968,910...153,008,845
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| G
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Nit1
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nitrilase 1
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increases expression
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ISO
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Arsenic Trioxide results in increased expression of NIT1 mRNA
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CTD |
PMID:39716349 |
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NCBI chr13:86,302,334...86,305,770
Ensembl chr13:86,298,387...86,305,770
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| G
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Nkd1
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NKD inhibitor of WNT signaling pathway 1
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multiple interactions
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ISO
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[Arsenic Trioxide co-treated with apatinib] results in decreased expression of NKD1 mRNA
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CTD |
PMID:39223679 |
|
NCBI chr19:34,649,803...34,722,846
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| G
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Nkd2
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NKD inhibitor of WNT signaling pathway 2
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increases expression
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ISO
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Arsenic Trioxide results in increased expression of NKD2 mRNA
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CTD |
PMID:19128835 |
|
NCBI chr 1:31,268,856...31,299,390
Ensembl chr 1:31,272,519...31,299,387
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| G
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Nktr
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natural killer cell triggering receptor
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decreases expression
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ISO
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Arsenic Trioxide results in decreased expression of NKTR mRNA
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CTD |
PMID:22521957 |
|
NCBI chr 8:130,255,541...130,298,001
Ensembl chr 8:130,259,461...130,298,008
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|
| G
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Nkx3-2
|
NK3 homeobox 2
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decreases expression
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ISO
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Arsenic Trioxide results in decreased expression of NKX3-2 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr14:73,396,198...73,398,585
Ensembl chr14:73,395,619...73,399,558
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| G
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Nlgn1
|
neuroligin 1
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increases expression decreases expression
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ISO
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Arsenic Trioxide results in increased expression of NLGN1 mRNA Arsenic Trioxide results in decreased expression of NLGN1 mRNA
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CTD |
PMID:20458559 PMID:26705709 |
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NCBI chr 2:110,184,987...111,110,316
Ensembl chr 2:110,186,573...110,909,984
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| G
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Nlrc4
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NLR family, CARD domain containing 4
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decreases expression
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ISO
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Arsenic Trioxide results in decreased expression of NLRC4 protein
|
CTD |
PMID:35226250 |
|
NCBI chr 6:26,743,658...26,771,783
Ensembl chr 6:26,743,698...26,770,563
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| G
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Nlrp12
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NLR family, pyrin domain containing 12
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increases expression multiple interactions
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ISO
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Arsenic Trioxide results in increased expression of NLRP12 mRNA Bortezomib promotes the reaction [Arsenic Trioxide results in increased expression of NLRP12 mRNA]
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CTD |
PMID:20471514 |
|
NCBI chr 1:74,848,020...74,885,945
Ensembl chr 1:74,848,063...74,876,341
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| G
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Nlrp1a
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NLR family, pyrin domain containing 1A
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increases expression multiple interactions
|
ISO
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Arsenic Trioxide results in increased expression of NLRP1 mRNA [sanguinarine co-treated with Arsenic Trioxide] results in increased expression of NLRP1 mRNA
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CTD |
PMID:24345465 |
|
NCBI chr10:56,277,134...56,332,229
Ensembl chr10:56,277,134...56,323,880
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|
| G
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Nlrp3
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NLR family, pyrin domain containing 3
|
multiple interactions increases expression
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ISO EXP
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[Arsenic Trioxide results in increased abundance of arsenite] which results in increased expression of NLRP3 mRNA; Arsenic Trioxide affects the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of NLRP3 mRNA]; Arsenic Trioxide affects the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of NLRP3 protein]; Arsenic Trioxide promotes the reaction [AS3MT protein binds to NLRP3 protein]; Arsenic Trioxide promotes the reaction [METTL14 protein binds to NLRP3 mRNA]; Taurine inhibits the reaction [Arsenic Trioxide results in increased expression of NLRP3 protein] [Arsenic Trioxide co-treated with Lipopolysaccharides] results in increased expression of NLRP3 protein; Febuxostat inhibits the reaction [Arsenic Trioxide results in increased expression of NLRP3 protein]; N-(1,2,3,5,6,7-hexahydro-S-indacen-4-ylcarbamoyl)-4-(2-hydroxy-2-propanyl)-2-furansulfonamide inhibits the reaction [[Arsenic Trioxide co-treated with Lipopolysaccharides] results in increased expression of NLRP3 protein]; Taurine inhibits the reaction [[Arsenic Trioxide co-treated with Lipopolysaccharides] results in increased expression of NLRP3 protein]; Taurine inhibits the reaction [Arsenic Trioxide results in increased expression of NLRP3 protein] [Arsenic Trioxide co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of NLRP3 protein; Arsenic Trioxide promotes the reaction [AS3MT protein binds to NLRP3 protein]; Arsenic Trioxide promotes the reaction [METTL14 protein binds to NLRP3 mRNA]; AS3MT mRNA promotes the reaction [Arsenic Trioxide promotes the reaction [METTL14 protein binds to NLRP3 mRNA]]; AS3MT mRNA promotes the reaction [Arsenic Trioxide results in increased expression of NLRP3 protein]; AS3MT mRNA promotes the reaction [Arsenic Trioxide results in increased stability of NLRP3 mRNA]; IGF2BP2 protein promotes the reaction [Arsenic Trioxide results in increased expression of NLRP3 protein]; IGF2BP2 protein promotes the reaction [Arsenic Trioxide results in increased stability of NLRP3 mRNA]; METTL14 protein promotes the reaction [Arsenic Trioxide results in increased expression of NLRP3 protein]; METTL14 protein promotes the reaction [Arsenic Trioxide results in increased stability of NLRP3 mRNA]; N-(1,2,3,5,6,7-hexahydro-S-indacen-4-ylcarbamoyl)-4-(2-hydroxy-2-propanyl)-2-furansulfonamide inhibits the reaction [[Arsenic Trioxide co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of NLRP3 protein]; N-(1,2,3,5,6,7-hexahydro-S-indacen-4-ylcarbamoyl)-4-(2-hydroxy-2-propanyl)-2-furansulfonamide inhibits the reaction [Arsenic Trioxide results in increased expression of NLRP3 protein]; Taurine inhibits the reaction [[Arsenic Trioxide co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of NLRP3 protein] Arsenic Trioxide results in increased expression of NLRP3 mRNA; Arsenic Trioxide results in increased expression of NLRP3 protein
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CTD |
PMID:30237538 PMID:30660605 PMID:35226250 PMID:36791901 PMID:37689273 PMID:38237221 More...
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NCBI chr10:44,826,299...44,853,373
Ensembl chr10:44,828,014...44,853,394
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| G
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Nme1
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NME/NM23 nucleoside diphosphate kinase 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of NME1 protein Arsenic Trioxide results in increased expression of NME1 mRNA; Arsenic Trioxide results in increased expression of NME1 protein
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CTD |
PMID:12452020 PMID:12478894 PMID:19822495 |
|
NCBI chr10:79,403,939...79,426,620
Ensembl chr10:79,403,940...79,413,310
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|
| G
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Nmt1
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N-myristoyltransferase 1
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increases expression
|
ISO
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Arsenic Trioxide results in increased expression of NMT1 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr10:88,488,918...88,525,496
Ensembl chr10:88,488,990...88,522,729
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|
| G
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Nmt2
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N-myristoyltransferase 2
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increases expression
|
ISO
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Arsenic Trioxide results in increased expression of NMT2 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr17:79,826,999...79,874,088
Ensembl chr17:79,826,999...79,870,259
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|
| G
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Nnt
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nicotinamide nucleotide transhydrogenase
|
increases expression
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ISO
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Arsenic Trioxide results in increased expression of NNT mRNA
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CTD |
PMID:39716349 |
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NCBI chr 2:53,144,157...53,237,857
Ensembl chr 2:53,144,160...53,237,310
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|
| G
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Nol3
|
nucleolar protein 3
|
decreases response to substance
|
ISO
|
NOL3 protein results in decreased susceptibility to Arsenic Trioxide
|
CTD |
PMID:20707922 |
|
NCBI chr19:50,066,493...50,068,175
Ensembl chr19:50,063,986...50,068,722
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|
| G
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Nol6
|
nucleolar protein 6
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of NOL6 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 5:61,055,863...61,083,249
Ensembl chr 5:61,055,863...61,083,264
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|
| G
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Nolc1
|
nucleolar and coiled-body phosphoprotein 1
|
decreases expression
|
ISO
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Arsenic Trioxide results in decreased expression of NOLC1 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 1:254,870,195...254,881,070
Ensembl chr 1:254,870,319...254,881,069
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|
| G
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Nop53
|
NOP53 ribosome biogenesis factor
|
increases expression
|
ISO
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Arsenic Trioxide results in increased expression of NOP53 mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr 1:85,757,271...85,765,089
Ensembl chr 1:85,756,586...85,765,089
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|
| G
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Nop56
|
NOP56 ribonucleoprotein
|
increases expression
|
ISO
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Arsenic Trioxide results in increased expression of NOP56 mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr 3:137,926,187...137,934,971
Ensembl chr 3:137,929,646...137,934,959
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|
| G
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Nos2
|
nitric oxide synthase 2
|
decreases expression increases expression multiple interactions
|
ISO EXP
|
Arsenic Trioxide results in decreased expression of NOS2 mRNA Arsenic Trioxide results in increased expression of NOS2 protein; Arsenic Trioxide results in increased expression of NOS2A mRNA Arsenic Trioxide inhibits the reaction [[Lipopolysaccharides results in increased expression of NOS2 protein] which results in increased chemical synthesis of Nitric Oxide] 4-amino-1,8-naphthalimide inhibits the reaction [Arsenic Trioxide results in increased expression of NOS2 protein] Arsenic Trioxide results in increased expression of NOS2 mRNA
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CTD |
PMID:20458559 PMID:20693187 PMID:23106696 PMID:25972196 PMID:28454374 PMID:31258454 More...
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NCBI chr10:64,313,335...64,349,221
Ensembl chr10:64,313,335...64,401,880
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|
| G
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Nos3
|
nitric oxide synthase 3
|
increases expression multiple interactions decreases expression
|
ISO EXP
|
Arsenic Trioxide results in increased expression of NOS3 mRNA Arsenic Trioxide results in increased phosphorylation of and results in increased activity of NOS3 protein Arsenic Trioxide results in decreased expression of NOS3 protein Nicorandil inhibits the reaction [Arsenic Trioxide results in decreased expression of NOS3 protein]
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CTD |
PMID:17559834 PMID:18414637 PMID:20458559 PMID:38741475 |
|
NCBI chr 4:11,686,088...11,706,604
Ensembl chr 4:11,686,268...11,706,664
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|
| G
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Notch1
|
notch receptor 1
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decreases response to substance decreases activity multiple interactions decreases expression increases expression
|
ISO
|
NOTCH1 protein results in decreased susceptibility to Arsenic Trioxide Arsenic Trioxide results in decreased activity of NOTCH1 protein 4-(4-(N-benzoylamino)anilino)-6-methoxy-7-(3-(1-morpholino)propoxy)quinazoline inhibits the reaction [Arsenic Trioxide results in decreased expression of NOTCH1 protein]; [Arsenic Trioxide results in decreased activity of NOTCH1 protein] which results in decreased phosphorylation of and results in decreased activity of STAT3 protein; Arsenic Trioxide inhibits the reaction [Homoharringtonine results in increased expression of NOTCH1 protein]; Arsenic Trioxide inhibits the reaction [PROM1 protein results in increased activity of NOTCH1 protein]; Arsenic Trioxide results in decreased expression of and results in increased phosphorylation of NOTCH1 protein; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Arsenic Trioxide results in decreased expression of NOTCH1 protein]; BI 2536 inhibits the reaction [Arsenic Trioxide results in decreased expression of NOTCH1 protein]; RO3280 inhibits the reaction [Arsenic Trioxide results in decreased expression of NOTCH1 protein] Arsenic Trioxide results in decreased expression of NOTCH1; Arsenic Trioxide results in decreased expression of NOTCH1 mRNA; Arsenic Trioxide results in decreased expression of NOTCH1 protein Arsenic Trioxide results in increased expression of NOTCH1 mRNA; Arsenic Trioxide results in increased expression of NOTCH1 protein
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CTD |
PMID:22949821 PMID:22978106 PMID:23497375 PMID:23542114 PMID:23832679 PMID:24801890 PMID:25088040 PMID:29738779 PMID:31307525 PMID:31597699 PMID:33634982 More...
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NCBI chr 3:29,676,040...29,721,613
Ensembl chr 3:29,676,171...29,721,613
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| G
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Notch2
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notch receptor 2
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multiple interactions
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ISO
|
[Arsenic Trioxide co-treated with Homoharringtonine] results in decreased expression of NOTCH2 protein
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CTD |
PMID:31307525 |
|
NCBI chr 2:188,299,336...188,432,823
Ensembl chr 2:188,299,336...188,432,823
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| G
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Nova1
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NOVA alternative splicing regulator 1
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decreases expression
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ISO
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Arsenic Trioxide results in decreased expression of NOVA1 mRNA
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CTD |
PMID:20458559 |
|
NCBI chr 6:69,506,983...69,632,437
Ensembl chr 6:69,506,983...69,632,437
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| G
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Nox1
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NADPH oxidase 1
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multiple interactions increases expression increases activity
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ISO EXP
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[ruxolitinib co-treated with Arsenic Trioxide] results in increased expression of NOX1 mRNA Arsenic Trioxide results in increased expression of NOX1 protein Arsenic Trioxide results in increased activity of NOX1 protein dapagliflozin inhibits the reaction [Arsenic Trioxide results in increased activity of NOX1 protein]; Febuxostat inhibits the reaction [Arsenic Trioxide results in increased expression of NOX1 protein]; Nicorandil inhibits the reaction [Arsenic Trioxide results in increased expression of NOX1 protein]
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CTD |
PMID:30012499 PMID:37689273 PMID:38070468 PMID:38741475 |
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NCBI chr X:101,572,338...101,625,571
Ensembl chr X:101,572,340...101,595,520
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| G
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Nox4
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NADPH oxidase 4
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multiple interactions
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ISO
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Arsenic Trioxide inhibits the reaction [TGFB1 protein results in increased expression of NOX4 mRNA]
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CTD |
PMID:24762191 |
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NCBI chr 1:150,313,736...150,491,480
Ensembl chr 1:150,313,728...150,491,483
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| G
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Np4
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defensin NP-4 precursor
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multiple interactions increases expression
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ISO
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[Tretinoin co-treated with Arsenic Trioxide] results in increased expression of DEFA4 mRNA Arsenic Trioxide results in increased expression of DEFA4 mRNA
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CTD |
PMID:15070760 PMID:15761015 PMID:15894607 |
|
NCBI chr16:77,197,061...77,199,713
Ensembl chr16:77,121,639...77,122,502 Ensembl chr16:77,121,639...77,122,502
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| G
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Npas1
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neuronal PAS domain protein 1
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increases expression
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ISO
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Arsenic Trioxide results in increased expression of NPAS1 mRNA
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CTD |
PMID:15761015 |
|
NCBI chr 1:86,295,509...86,316,018
Ensembl chr 1:86,295,515...86,314,893
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| G
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Npc1
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NPC intracellular cholesterol transporter 1
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decreases expression
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ISO
|
Arsenic Trioxide results in decreased expression of NPC1 protein
|
CTD |
PMID:25419056 |
|
NCBI chr18:3,654,237...3,699,853
Ensembl chr18:3,654,237...3,699,800
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| G
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Nphp4
|
nephrocystin 4
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multiple interactions
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ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to NPHP4 protein]
|
CTD |
PMID:26598702 |
|
NCBI chr 5:168,270,522...168,356,393
Ensembl chr 5:168,271,073...168,358,242
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| G
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Nphs2
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NPHS2 stomatin family member, podocin
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increases expression
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ISO
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Arsenic Trioxide results in increased expression of NPHS2 mRNA
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CTD |
PMID:20458559 |
|
NCBI chr13:70,993,622...71,011,585
Ensembl chr13:70,999,186...71,011,572
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| G
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Nploc4
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NPL4 homolog, ubiquitin recognition factor
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multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to NPLOC4 protein]
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CTD |
PMID:26598702 |
|
NCBI chr10:106,152,756...106,208,306
Ensembl chr10:106,153,173...106,208,264
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| G
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Npm1
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nucleophosmin 1
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increases expression increases response to substance multiple interactions affects response to substance
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ISO
|
Arsenic Trioxide results in increased expression of NPM1 mRNA NPM1 protein mutant form results in increased susceptibility to Arsenic Trioxide Acetylcysteine inhibits the reaction [NPM1 protein mutant form results in increased susceptibility to Arsenic Trioxide] NPM1 protein affects the susceptibility to Arsenic Trioxide
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CTD |
PMID:20458559 PMID:22521957 PMID:23877794 |
|
NCBI chr10:18,245,739...18,255,913
Ensembl chr10:18,245,740...18,256,024 Ensembl chr X:18,245,740...18,256,024
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| G
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Npr3
|
natriuretic peptide receptor 3
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of NPR3 mRNA
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CTD |
PMID:35676786 |
|
NCBI chr 2:62,592,557...62,660,497
Ensembl chr 2:62,597,668...62,660,066
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| G
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Nptn
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neuroplastin
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increases expression
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ISO
|
Arsenic Trioxide results in increased expression of NPTN protein
|
CTD |
PMID:25419056 |
|
NCBI chr 8:67,892,678...67,959,231
Ensembl chr 8:67,892,702...67,959,236
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| G
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Nptx2
|
neuronal pentraxin 2
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decreases expression increases expression
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ISO
|
Arsenic Trioxide results in decreased expression of NPTX2 mRNA Arsenic Trioxide results in increased expression of NPTX2 mRNA
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CTD |
PMID:15761015 PMID:26705709 |
|
NCBI chr12:15,151,136...15,162,045
Ensembl chr12:15,151,136...15,162,045
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| G
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Npy
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neuropeptide Y
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increases expression
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ISO
|
Arsenic Trioxide results in increased expression of NPY mRNA
|
CTD |
PMID:11027660 |
|
NCBI chr 4:80,212,111...80,219,310
Ensembl chr 4:80,212,111...80,219,310
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| G
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Npy1r
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neuropeptide Y receptor Y1
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of NPY1R mRNA
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CTD |
PMID:39716349 |
|
NCBI chr16:27,804,416...27,814,070
Ensembl chr16:27,804,416...27,813,387
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| G
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Nqo1
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NAD(P)H quinone dehydrogenase 1
|
increases expression multiple interactions decreases expression decreases response to substance
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ISO EXP
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Arsenic Trioxide results in increased expression of NQO1 mRNA; Arsenic Trioxide results in increased expression of NQO1 protein [Arsenic Trioxide results in decreased expression of MEG3 protein] promotes the reaction [NQO1 protein binds to FSCN1 protein]; [Arsenic Trioxide results in decreased expression of MEG3 protein] which results in increased expression of NQO1 protein; [Arsenic Trioxide results in increased abundance of Arsenic] which results in increased expression of NQO1 mRNA; [Arsenic Trioxide results in increased abundance of Arsenic] which results in increased expression of NQO1 protein; [Resveratrol co-treated with Arsenic Trioxide] results in increased expression of NQO1 protein; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased expression of NQO1 protein]; allicin inhibits the reaction [Arsenic Trioxide results in decreased expression of NQO1 protein]; Arsenic Trioxide promotes the reaction [FSCN1 protein binds to NQO1 protein]; MEG3 inhibits the reaction [Arsenic Trioxide results in increased expression of NQO1 protein]; MIR155 mRNA inhibits the reaction [Arsenic Trioxide results in decreased expression of NQO1 protein]; NFE2L2 protein promotes the reaction [Arsenic Trioxide results in increased expression of NQO1 protein]; NQO1 promotes the reaction [Arsenic Trioxide results in increased expression of FSCN1 protein]; Tretinoin inhibits the reaction [Arsenic Trioxide results in increased expression of NQO1 protein] Arsenic Trioxide results in decreased expression of NQO1 mRNA [Arsenic Trioxide co-treated with Grape Seed Proanthocyanidins] results in increased expression of NQO1 mRNA; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in decreased expression of NQO1 mRNA]; AHR protein promotes the reaction [Arsenic Trioxide results in increased expression of NQO1 protein]; Arsenic Trioxide promotes the reaction [Lutein results in increased expression of NQO1 mRNA]; Arsenic Trioxide promotes the reaction [Lutein results in increased expression of NQO1 protein]; Arsenic Trioxide promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of and results in increased activity of NQO1 protein]; Arsenic Trioxide promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of NQO1 mRNA]; Arsenic Trioxide results in increased expression of and results in increased activity of NQO1 protein; Buthionine Sulfoximine promotes the reaction [Arsenic Trioxide promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of NQO1 mRNA]]; Lutein promotes the reaction [Arsenic Trioxide results in increased expression of NQO1 mRNA]; Lutein promotes the reaction [Arsenic Trioxide results in increased expression of NQO1 protein]; NFE2L2 protein affects the reaction [Arsenic Trioxide results in increased expression of NQO1 mRNA]; NFE2L2 protein promotes the reaction [Arsenic Trioxide results in increased expression of NQO1 protein]; Tetrachlorodibenzodioxin promotes the reaction [Arsenic Trioxide results in increased expression of and results in increased activity of NQO1 protein]; Tetrachlorodibenzodioxin promotes the reaction [Arsenic Trioxide results in increased expression of NQO1 mRNA] NQO1 protein results in decreased susceptibility to Arsenic Trioxide crocin inhibits the reaction [Arsenic Trioxide results in decreased expression of NQO1 protein]
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CTD |
PMID:16274885 PMID:19417148 PMID:20707922 PMID:21533816 PMID:22155346 PMID:23426167 PMID:24356939 PMID:25003661 PMID:25419056 PMID:25424538 PMID:25815309 PMID:25966753 PMID:26187899 PMID:27561292 PMID:27829220 PMID:29049341 PMID:29260515 PMID:29876539 PMID:32920515 PMID:33434570 PMID:35276128 PMID:37424815 PMID:39630573 More...
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NCBI chr19:52,205,374...52,220,267
Ensembl chr19:52,205,314...52,220,260
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| G
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Nqo2
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N-ribosyldihydronicotinamide:quinone dehydrogenase 2
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of NQO2 mRNA
|
CTD |
PMID:21461292 |
|
NCBI chr17:31,114,825...31,144,062
Ensembl chr17:31,114,529...31,143,662
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| G
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Nr1h2
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nuclear receptor subfamily 1, group H, member 2
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decreases expression increases expression multiple interactions
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ISO EXP
|
Arsenic Trioxide results in decreased expression of NR1H2 mRNA; Arsenic Trioxide results in decreased expression of NR1H2 protein Arsenic Trioxide results in increased expression of NR1H2 mRNA Cholesterol, Dietary promotes the reaction [Arsenic Trioxide results in decreased expression of NR1H2 protein]
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CTD |
PMID:15073043 PMID:21851829 PMID:27622732 |
|
NCBI chr 1:104,178,483...104,183,863
Ensembl chr 1:104,178,234...104,183,863
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| G
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Nr2f2
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nuclear receptor subfamily 2, group F, member 2
|
decreases expression
|
ISO
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Arsenic Trioxide results in decreased expression of NR2F2 mRNA
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CTD |
PMID:20458559 |
|
NCBI chr 1:133,419,161...133,434,290
Ensembl chr 1:133,420,227...133,431,975
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| G
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Nr2f6
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nuclear receptor subfamily 2, group F, member 6
|
decreases expression
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ISO
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Arsenic Trioxide results in decreased expression of NR2F6 mRNA
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CTD |
PMID:20458559 |
|
NCBI chr16:18,080,003...18,087,449
Ensembl chr16:18,080,003...18,087,449
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| G
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Nr3c1
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nuclear receptor subfamily 3, group C, member 1
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multiple interactions decreases expression
|
ISO EXP
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Arsenic Trioxide affects the reaction [NR3C1 protein modified form binds to DAXX protein]; Arsenic Trioxide inhibits the reaction [[DAXX protein binds to NR3C1 protein] which binds to TSC22D3 promoter]; Arsenic Trioxide results in decreased expression of and results in increased degradation of NR3C1 protein; Diosgenin inhibits the reaction [Arsenic Trioxide results in decreased expression of NR3C1 protein]; NR3C1 promotes the reaction [Diosgenin inhibits the reaction [Arsenic Trioxide results in decreased expression of CDH5 protein]]; NR3C1 promotes the reaction [Diosgenin inhibits the reaction [Arsenic Trioxide results in decreased expression of PECAM1 protein]]; NR3C1 promotes the reaction [Diosgenin inhibits the reaction [Arsenic Trioxide results in increased expression of ACTA2 protein]]; NR3C1 promotes the reaction [Diosgenin inhibits the reaction [Arsenic Trioxide results in increased expression of TAGLN protein]] Diosgenin inhibits the reaction [Arsenic Trioxide results in decreased expression of and results in increased degradation of NR3C1 protein]; NR3C1 promotes the reaction [Diosgenin inhibits the reaction [Arsenic Trioxide results in increased expression of and results in increased secretion of IL6 protein]]
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CTD |
PMID:17081986 PMID:39059093 |
|
NCBI chr18:31,522,783...31,644,508
Ensembl chr18:31,522,783...31,643,843
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| G
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Nr4a1
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nuclear receptor subfamily 4, group A, member 1
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decreases expression increases expression
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ISO
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Arsenic Trioxide results in decreased expression of NR4A1 mRNA Arsenic Trioxide results in increased expression of NR4A1 mRNA
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CTD |
PMID:20458559 PMID:37969188 |
|
NCBI chr 7:134,247,153...134,268,044
Ensembl chr 7:134,247,192...134,268,041
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| G
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Nr4a2
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nuclear receptor subfamily 4, group A, member 2
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decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of NR4A2 mRNA
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CTD |
PMID:26705709 |
|
NCBI chr 3:62,098,739...62,115,926
Ensembl chr 3:62,098,743...62,106,769
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| G
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Nr4a3
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nuclear receptor subfamily 4, group A, member 3
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of NR4A3 mRNA
|
CTD |
PMID:35676786 |
|
NCBI chr 5:67,157,141...67,198,287
Ensembl chr 5:67,157,375...67,198,285
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| G
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Nrep
|
neuronal regeneration related protein
|
decreases expression
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ISO
|
Arsenic Trioxide results in decreased expression of NREP mRNA
|
CTD |
PMID:15725085 |
|
NCBI chr18:25,291,219...25,320,742
Ensembl chr18:25,291,219...25,320,742
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| G
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Nrf1
|
nuclear respiratory factor 1
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affects methylation
|
ISO
|
Arsenic Trioxide affects the methylation of NRF1 promoter
|
CTD |
PMID:26046465 |
|
NCBI chr 4:59,632,366...59,738,166
Ensembl chr 4:59,632,372...59,738,353
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| G
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Nrg1
|
neuregulin 1
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increases expression decreases expression
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ISO
|
Arsenic Trioxide results in increased expression of NRG1 mRNA Arsenic Trioxide results in decreased expression of NRG1 mRNA
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CTD |
PMID:22521957 PMID:35676786 |
|
NCBI chr16:65,954,084...67,007,484
Ensembl chr16:65,953,865...66,999,849
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| G
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Nrg3
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neuregulin 3
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increases expression
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ISO
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Arsenic Trioxide results in increased expression of NRG3 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr16:14,256,540...15,374,107
Ensembl chr16:14,257,148...15,374,147
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| G
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Nrip3
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nuclear receptor interacting protein 3
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increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of NRIP3 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 1:173,224,532...173,249,829
Ensembl chr 1:173,224,532...173,251,769
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| G
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Nrtn
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neurturin
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decreases expression
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ISO
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Arsenic Trioxide results in decreased expression of NRTN mRNA
|
CTD |
PMID:26705709 |
|
NCBI chr 9:1,669,099...1,674,957
Ensembl chr 9:1,641,618...1,675,133
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| G
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Nrxn3
|
neurexin 3
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decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of NRXN3 mRNA
|
CTD |
PMID:26705709 |
|
NCBI chr 6:113,372,667...115,004,073
Ensembl chr 6:113,443,524...115,002,540
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| G
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Nsa2
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NSA2 ribosome biogenesis factor
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of NSA2 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 2:30,177,753...30,184,004
Ensembl chr 2:30,177,702...30,184,031
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| G
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Nsd2
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nuclear receptor binding SET domain protein 2
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increases expression
|
ISO
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Arsenic Trioxide results in increased expression of NSD2 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr14:81,057,727...81,135,866
Ensembl chr14:81,057,727...81,123,027
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| G
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Nsd3
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nuclear receptor binding SET domain protein 3
|
decreases expression
|
ISO
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Arsenic Trioxide results in decreased expression of NSD3 mRNA
|
CTD |
PMID:22521957 |
|
NCBI chr16:73,056,748...73,170,082
Ensembl chr16:73,061,694...73,168,130
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| G
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Nsdhl
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NAD(P) dependent 3-beta-hydroxysteroid dehydrogenase NSDHL
|
multiple interactions decreases expression
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to NSDHL protein] Arsenic Trioxide results in decreased expression of NSDHL protein
|
CTD |
PMID:25419056 PMID:26598702 |
|
NCBI chr X:155,817,301...155,848,224
Ensembl chr X:155,817,340...155,848,220
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| G
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Nsl1
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NSL1 component of MIS12 kinetochore complex
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of NSL1 mRNA
|
CTD |
PMID:22521957 |
|
NCBI chr13:105,176,163...105,205,179
Ensembl chr13:105,180,183...105,196,117
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| G
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Nt5c
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5', 3'-nucleotidase, cytosolic
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decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of NT5C mRNA
|
CTD |
PMID:21461292 |
|
NCBI chr10:101,238,552...101,240,666
Ensembl chr10:101,238,576...101,240,865
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| G
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Nt5e
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5' nucleotidase, ecto
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of NT5E mRNA
|
CTD |
PMID:22521957 |
|
NCBI chr 8:98,150,925...98,195,646
Ensembl chr 8:98,150,900...98,195,645
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| G
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Ntaq1
|
N-terminal glutamine amidase 1
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to NTAQ1 protein]
|
CTD |
PMID:26598702 |
|
NCBI chr 7:91,573,816...91,593,980
Ensembl chr 7:91,553,676...91,626,071
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| G
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Nthl1
|
nth-like DNA glycosylase 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of NTHL1 mRNA
|
CTD |
PMID:35676786 |
|
NCBI chr10:14,160,334...14,166,502
Ensembl chr10:14,160,330...14,166,966
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| G
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Ntrk1
|
neurotrophic receptor tyrosine kinase 1
|
decreases expression increases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of NTRK1 Arsenic Trioxide results in increased expression of NTRK1 mRNA; Arsenic Trioxide results in increased expression of NTRK1 protein
|
CTD |
PMID:16569477 PMID:29898774 |
|
NCBI chr 2:175,534,844...175,551,664
Ensembl chr 2:175,534,844...175,551,787
|
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| G
|
Ntrk2
|
neurotrophic receptor tyrosine kinase 2
|
increases sumoylation decreases expression multiple interactions increases expression
|
ISO
|
Arsenic Trioxide results in increased sumoylation of NTRK2 protein Arsenic Trioxide results in decreased expression of NTRK2 mRNA; Arsenic Trioxide results in decreased expression of NTRK2 protein Arsenic Trioxide promotes the reaction [Reserpine results in decreased expression of NTRK2 protein] Arsenic Trioxide results in increased expression of NTRK2 mRNA; Arsenic Trioxide results in increased expression of NTRK2 protein
|
CTD |
PMID:16569477 PMID:16711005 PMID:26114099 PMID:26705709 PMID:28318385 PMID:29898774 More...
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|
NCBI chr17:5,560,558...5,875,899
Ensembl chr17:5,564,570...5,874,628
|
|
| G
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Ntrk3
|
neurotrophic receptor tyrosine kinase 3
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of NTRK3 mRNA; Arsenic Trioxide results in increased expression of NTRK3 protein
|
CTD |
PMID:29898774 |
|
NCBI chr 1:141,526,192...141,913,575
Ensembl chr 1:141,542,569...141,913,004
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|
| G
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Nts
|
neurotensin
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of NTS mRNA
|
CTD |
PMID:26705709 |
|
NCBI chr 7:39,451,484...39,460,888
Ensembl chr 7:39,451,073...39,460,961
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| G
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Ntsr1
|
neurotensin receptor 1
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of NTSR1 mRNA
|
CTD |
PMID:25258189 |
|
NCBI chr 3:187,983,778...188,033,934
Ensembl chr 3:187,983,778...188,033,934
|
|
| G
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Nuak1
|
NUAK family kinase 1
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of NUAK1 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 7:21,217,729...21,289,608
Ensembl chr 7:21,217,681...21,289,354
|
|
| G
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Nuak2
|
NUAK family kinase 2
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of NUAK2 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr13:46,305,744...46,322,755
Ensembl chr13:46,305,975...46,322,748
|
|
| G
|
Nubp1
|
NUBP iron-sulfur cluster assembly factor 1
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to NUBP1 protein]
|
CTD |
PMID:26598702 |
|
NCBI chr10:5,766,157...5,777,648
Ensembl chr10:5,766,157...5,786,422
|
|
| G
|
Nubpl
|
NUBP iron-sulfur cluster assembly factor, mitochondrial
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of NUBPL mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr 6:75,294,609...75,516,603
Ensembl chr 6:75,294,632...75,516,601
|
|
| G
|
Nucb2
|
nucleobindin 2
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of NUCB2 mRNA
|
CTD |
PMID:17547211 |
|
NCBI chr 1:180,185,121...180,221,644
Ensembl chr 1:180,199,551...180,230,116
|
|
| G
|
Nudt12
|
nudix hydrolase 12
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to NUDT12 protein]
|
CTD |
PMID:26598702 |
|
NCBI chr 9:106,188,930...106,202,340
Ensembl chr 9:106,189,661...106,202,340
|
|
| G
|
Nudt16l2
|
nudix hydrolase 16 like 2
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of NUDT16L2P mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr 8:114,633,615...114,635,346
Ensembl chr 8:114,632,701...114,635,296
|
|
| G
|
Nudt18
|
nudix hydrolase 18
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of NUDT18 mRNA
|
CTD |
PMID:15761015 |
|
NCBI chr15:52,060,297...52,062,822
Ensembl chr15:52,060,293...52,063,661
|
|
| G
|
Nudt4
|
nudix hydrolase 4
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to NUDT4 protein]
|
CTD |
PMID:26598702 |
|
NCBI chr 7:32,074,978...32,091,491
Ensembl chr 7:32,075,002...32,091,491
|
|
| G
|
Nudt7
|
nudix hydrolase 7
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of NUDT7 mRNA
|
CTD |
PMID:27829220 |
|
NCBI chr19:59,034,808...59,049,148
Ensembl chr19:59,034,839...59,063,994
|
|
| G
|
Numa1
|
nuclear mitotic apparatus protein 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of NUMA1 protein
|
CTD |
PMID:25419056 |
|
NCBI chr 1:165,709,893...165,784,848
Ensembl chr 1:165,709,905...165,784,848
|
|
| G
|
Numb
|
NUMB, endocytic adaptor protein
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of NUMB mRNA
|
CTD |
PMID:19128835 |
|
NCBI chr 6:109,162,499...109,284,527
Ensembl chr 6:109,162,499...109,284,463
|
|
| G
|
Nup107
|
nucleoporin 107
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of NUP107 mRNA
|
CTD |
PMID:17547211 |
|
NCBI chr 7:55,239,610...55,285,050
Ensembl chr 7:55,239,613...55,285,234
|
|
| G
|
Nup153
|
nucleoporin 153
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of NUP153 mRNA
|
CTD |
PMID:21461292 |
|
NCBI chr17:18,178,434...18,231,109
Ensembl chr17:18,178,456...18,231,109
|
|
| G
|
Nup37
|
nucleoporin 37
|
decreases response to substance
|
ISO
|
NUP37 protein results in decreased susceptibility to Arsenic Trioxide
|
CTD |
PMID:20707922 |
|
NCBI chr 7:24,443,998...24,497,088
Ensembl chr 7:24,463,301...24,508,741
|
|
| G
|
Nupr1
|
nuclear protein 1, transcriptional regulator
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of NUPR1 mRNA
|
CTD |
PMID:19128835 |
|
NCBI chr 1:190,643,866...190,645,901
Ensembl chr 1:190,643,867...190,645,901
|
|
| G
|
Nusap1
|
nucleolar and spindle associated protein 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of NUSAP1 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 3:127,057,220...127,092,779
Ensembl chr 3:127,057,265...127,087,237
|
|
| G
|
Nvl
|
nuclear VCP-like
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of NVL mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr13:95,385,389...95,438,490
Ensembl chr13:95,372,641...95,442,291
|
|
| G
|
Nxph2
|
neurexophilin 2
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of NXPH2 mRNA
|
CTD |
PMID:26705709 |
|
NCBI chr 3:26,373,858...26,392,392
Ensembl chr 3:26,153,756...26,391,876
|
|
| G
|
Obp2b
|
odorant binding protein 2B
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of OBP2B mRNA
|
CTD |
PMID:25258189 |
|
NCBI chr 3:28,960,375...28,983,394
Ensembl chr 3:28,980,186...28,983,370
|
|
| G
|
Obsl1
|
obscurin like cytoskeletal adaptor 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of OBSL1 mRNA
|
CTD |
PMID:15761015 |
|
NCBI chr 9:84,416,447...84,442,415
Ensembl chr 9:84,416,240...84,442,415
|
|
| G
|
Oc90
|
otoconin 90
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of OC90 mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr 7:99,524,975...99,558,386
Ensembl chr 7:99,524,975...99,558,386
|
|
| G
|
Ocln
|
occludin
|
decreases expression multiple interactions
|
ISO
|
Arsenic Trioxide results in decreased expression of OCLN mRNA; Arsenic Trioxide results in decreased expression of OCLN protein 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Arsenic Trioxide results in decreased expression of OCLN protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in decreased expression of OCLN mRNA]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in decreased expression of OCLN protein]; Resveratrol inhibits the reaction [Arsenic Trioxide results in decreased expression of OCLN protein]; SB 203580 inhibits the reaction [Arsenic Trioxide results in decreased expression of OCLN protein] [Arsenic Trioxide results in increased abundance of arsenite] which results in decreased expression of OCLN mRNA; Butyrates inhibits the reaction [Arsenic Trioxide results in decreased expression of OCLN protein]; MIR122 mRNA affects the reaction [Butyrates inhibits the reaction [Arsenic Trioxide results in decreased expression of OCLN protein]]
|
CTD |
PMID:30032600 PMID:30225639 PMID:32683294 PMID:36473683 PMID:36791901 |
|
NCBI chr 2:33,391,303...33,442,207
Ensembl chr 2:33,391,303...33,430,411
|
|
| G
|
Odc1
|
ornithine decarboxylase 1
|
multiple interactions
|
ISO EXP
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to ODC1 protein] Arsenic Trioxide promotes the reaction [Berberine results in decreased expression of ODC1 protein]
|
CTD |
PMID:18294404 PMID:26598702 |
|
NCBI chr 6:46,058,439...46,065,148
Ensembl chr 6:46,058,463...46,065,146
|
|
| G
|
Ogfod1
|
2-oxoglutarate and iron-dependent oxygenase domain containing 1
|
decreases expression multiple interactions
|
ISO
|
Arsenic Trioxide results in decreased expression of OGFOD1 mRNA [Arsenic Trioxide co-treated with Ascorbic Acid] results in decreased expression of OGFOD1 mRNA
|
CTD |
PMID:25555879 |
|
NCBI chr19:10,950,950...10,980,519
Ensembl chr19:10,950,060...10,980,519
|
|
| G
|
Ogg1
|
8-oxoguanine DNA glycosylase
|
affects activity decreases expression
|
ISO
|
OGG1 protein affects the activity of Arsenic Trioxide Arsenic Trioxide results in decreased expression of OGG1 mRNA
|
CTD |
PMID:17101720 PMID:20458559 |
|
NCBI chr 4:148,030,237...148,037,599
Ensembl chr 4:148,030,349...148,037,604
|
|
| G
|
Ogn
|
osteoglycin
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of OGN mRNA
|
CTD |
PMID:26705709 |
|
NCBI chr17:15,238,500...15,259,167
Ensembl chr17:15,238,500...15,259,252
|
|
| G
|
Ogt
|
O-linked N-acetylglucosamine (GlcNAc) transferase
|
increases response to substance
|
ISO
|
OGT protein results in increased susceptibility to Arsenic Trioxide
|
CTD |
PMID:20707922 |
|
NCBI chr X:70,811,317...70,856,123
Ensembl chr X:70,811,319...70,856,123
|
|
| G
|
Olfm1
|
olfactomedin 1
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of OLFM1 mRNA
|
CTD |
PMID:35676786 |
|
NCBI chr 3:31,918,512...31,956,261
Ensembl chr 3:31,918,573...31,956,260
|
|
| G
|
Olfml2a
|
olfactomedin-like 2A
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of OLFML2A mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 3:43,098,299...43,127,621
Ensembl chr 3:43,098,299...43,127,621
|
|
| G
|
Olfml3
|
olfactomedin-like 3
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of OLFML3 mRNA
|
CTD |
PMID:20458559 PMID:22521957 |
|
NCBI chr 2:193,932,665...193,935,494
Ensembl chr 2:193,932,665...193,935,494
|
|
| G
|
Olig2
|
oligodendrocyte transcription factor 2
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to OLIG2 protein]
|
CTD |
PMID:26598702 |
|
NCBI chr11:43,961,585...43,964,961
Ensembl chr11:43,958,940...43,968,634
|
|
| G
|
Olr1
|
oxidized low density lipoprotein receptor 1
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of OLR1 mRNA
|
CTD |
PMID:19128835 |
|
NCBI chr 4:164,612,460...164,635,082
Ensembl chr 4:164,612,463...164,634,598
|
|
| G
|
Onecut2
|
one cut homeobox 2
|
multiple interactions
|
ISO
|
[Arsenic Trioxide co-treated with Tretinoin] results in decreased expression of ONECUT2 mRNA
|
CTD |
PMID:38179723 |
|
NCBI chr18:60,101,967...60,161,095
Ensembl chr18:60,102,126...60,107,668
|
|
| G
|
Opa1
|
OPA1, mitochondrial dynamin like GTPase
|
multiple interactions increases expression
|
ISO EXP
|
salvianolic acid A inhibits the reaction [Arsenic Trioxide results in increased expression of OPA1 protein]
|
CTD |
PMID:29867492 |
|
NCBI chr11:84,612,943...84,690,025
Ensembl chr11:84,615,340...84,689,955
|
|
| G
|
Opalin
|
oligodendrocytic myelin paranodal and inner loop protein
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of OPALIN mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 1:249,840,539...249,858,423
Ensembl chr 1:249,840,539...249,858,190
|
|
| G
|
Opcml
|
opioid binding protein/cell adhesion molecule-like
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of OPCML mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 8:34,451,629...35,562,897
Ensembl chr 8:34,451,500...35,558,966
|
|
| G
|
Opn3
|
opsin 3
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of OPN3 mRNA
|
CTD |
PMID:22521957 |
|
NCBI chr13:90,121,560...90,152,076
Ensembl chr13:90,121,560...90,152,076
|
|
| G
|
Optn
|
optineurin
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to OPTN protein]
|
CTD |
PMID:26598702 |
|
NCBI chr17:78,118,847...78,169,543
Ensembl chr17:78,118,866...78,169,543
|
|
| G
|
Or10a5
|
olfactory receptor family 10 subfamily A member 5
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of OR10A5 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 1:170,275,374...170,276,327
Ensembl chr 1:170,275,353...170,276,327
|
|
| G
|
Or51e1
|
olfactory receptor family 51 subfamily E member 1
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of OR51E1 mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr 1:166,554,112...166,564,147
Ensembl chr 1:166,554,061...166,564,105
|
|
| G
|
Orc4
|
origin recognition complex, subunit 4
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of ORC4 mRNA
|
CTD |
PMID:15761015 |
|
NCBI chr 3:53,700,046...53,743,293
Ensembl chr 3:53,703,615...53,742,264
|
|
| G
|
Os9
|
OS9, endoplasmic reticulum lectin
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of OS9 mRNA
|
CTD |
PMID:17547211 |
|
NCBI chr 7:64,802,517...64,829,185
Ensembl chr 7:64,802,103...64,829,070
|
|
| G
|
Osbpl6
|
oxysterol binding protein-like 6
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of OSBPL6 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 3:81,751,020...81,948,186
Ensembl chr 3:81,750,982...81,946,615
|
|
| G
|
Osbpl8
|
oxysterol binding protein-like 8
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of OSBPL8 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 7:48,483,259...48,636,151
Ensembl chr 7:48,483,022...48,636,151
|
|
| G
|
Osbpl9
|
oxysterol binding protein-like 9
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of OSBPL9 mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr 5:129,047,776...129,190,838
Ensembl chr 5:129,047,781...129,190,836
|
|
| G
|
Oscar
|
osteoclast associated Ig-like receptor
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of OSCAR mRNA
|
CTD |
PMID:19128835 |
|
NCBI chr 1:74,521,626...74,529,119
Ensembl chr 1:74,515,001...74,529,119
|
|
| G
|
Osgepl1
|
O-sialoglycoprotein endopeptidase-like 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of OSGEPL1 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 9:55,707,389...55,725,325
Ensembl chr 9:55,707,392...55,721,346
|
|
| G
|
Ostc
|
oligosaccharyltransferase complex non-catalytic subunit
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of OSTC mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 2:221,924,727...221,940,253
Ensembl chr 2:221,874,948...221,940,267
|
|
| G
|
Ovol2
|
ovo-like zinc finger 2
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to OVOL2 protein]
|
CTD |
PMID:26598702 |
|
NCBI chr 3:152,130,767...152,160,487
Ensembl chr 3:152,130,767...152,160,487
|
|
| G
|
P2ry1
|
purinergic receptor P2Y1
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of P2RY1 mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr 2:147,391,661...147,397,870
Ensembl chr 2:147,390,681...147,398,027
|
|
| G
|
P2ry13
|
purinergic receptor P2Y13
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of P2RY13 protein
|
CTD |
PMID:25258189 |
|
NCBI chr 2:145,620,321...145,624,730
Ensembl chr 2:145,619,655...145,622,787
|
|
| G
|
P3h2
|
prolyl 3-hydroxylase 2
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of P3H2 mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr11:88,139,086...88,280,221
Ensembl chr11:88,139,078...88,281,203
|
|
| G
|
P4ha1
|
prolyl 4-hydroxylase subunit alpha 1
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of P4HA1 mRNA
|
CTD |
PMID:15725085 |
|
NCBI chr20:27,784,696...27,895,785
Ensembl chr20:27,845,141...27,895,404
|
|
| G
|
P4hb
|
prolyl 4-hydroxylase subunit beta
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of P4HB mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr10:106,335,300...106,346,911
Ensembl chr10:106,335,300...106,346,911
|
|
| G
|
P4htm
|
prolyl 4-hydroxylase, transmembrane
|
decreases response to substance
|
ISO
|
P4HTM protein results in decreased susceptibility to Arsenic Trioxide
|
CTD |
PMID:20707922 |
|
NCBI chr 8:118,153,158...118,172,199
Ensembl chr 8:118,153,158...118,171,002
|
|
| G
|
Pabpc4
|
poly(A) binding protein, cytoplasmic 4
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to PABPC4 protein]
|
CTD |
PMID:26598702 |
|
NCBI chr 5:140,847,835...140,864,089
Ensembl chr 5:140,848,225...140,864,087
|
|
| G
|
Pabpc6
|
poly(A) binding protein, cytoplasmic 6
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of PABPC3 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 1:53,592,902...53,595,978
Ensembl chr 1:53,592,884...53,595,973
|
|
| G
|
Pacsin2
|
protein kinase C and casein kinase substrate in neurons 2
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to PACSIN2 protein]
|
CTD |
PMID:26598702 |
|
NCBI chr 7:116,385,571...116,478,609
Ensembl chr 7:116,384,190...116,478,537
|
|
| G
|
Padi1
|
peptidyl arginine deiminase 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of PADI1 mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr 5:158,402,614...158,435,077
Ensembl chr 5:158,402,614...158,435,077
|
|
| G
|
Pafah1b1
|
platelet-activating factor acetylhydrolase 1b, regulatory subunit 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of PAFAH1B1 protein
|
CTD |
PMID:25419056 |
|
NCBI chr10:60,031,441...60,090,259
Ensembl chr10:60,032,514...60,090,196
|
|
| G
|
Pafah1b3
|
platelet-activating factor acetylhydrolase 1b, catalytic subunit 3
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of PAFAH1B3 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 1:90,009,085...90,011,611
Ensembl chr 1:90,009,085...90,011,611
|
|
| G
|
Pafah2
|
platelet-activating factor acetylhydrolase 2
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of PAFAH2 mRNA
|
CTD |
PMID:15761015 |
|
NCBI chr 5:151,890,751...151,919,896
Ensembl chr 5:151,896,832...151,919,894
|
|
| G
|
Paics
|
phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of PAICS mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr14:31,553,355...31,586,843
Ensembl chr14:31,553,357...31,587,027
|
|
| G
|
Pak2
|
p21 (RAC1) activated kinase 2
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to PAK2 protein]
|
CTD |
PMID:26598702 |
|
NCBI chr11:82,212,896...82,273,803
Ensembl chr11:82,212,951...82,273,803
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| G
|
Pak3
|
p21 (RAC1) activated kinase 3
|
multiple interactions
|
ISO
|
[Tretinoin co-treated with Arsenic Trioxide] results in decreased expression of PAK3 mRNA
|
CTD |
PMID:15894607 |
|
NCBI chr X:111,912,967...112,171,037
Ensembl chr X:111,913,059...112,165,035
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| G
|
Pakap
|
paralemmin A kinase anchor protein
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of PALM2AKAP2 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 5:76,976,906...77,443,656
Ensembl chr 5:76,977,112...77,443,656
|
|
| G
|
Palld
|
palladin, cytoskeletal associated protein
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of PALLD mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr16:33,238,943...33,632,236
Ensembl chr16:33,238,956...33,632,232
|
|
| G
|
Pals1
|
protein associated with LIN7 1, MAGUK p55 family member
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of PALS1 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 6:103,327,965...103,384,543
Ensembl chr 6:103,281,154...103,387,209
|
|
| G
|
Pan2
|
poly(A) specific ribonuclease subunit PAN2
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of PAN2 mRNA
|
CTD |
PMID:27829220 |
|
NCBI chr 7:1,313,654...1,332,252
Ensembl chr 7:1,313,655...1,332,252
|
|
| G
|
Pank2
|
pantothenate kinase 2
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of PANK2 mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr 3:138,936,448...138,974,196
Ensembl chr 3:138,936,452...138,974,194
|
|
| G
|
Panx2
|
pannexin 2
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of PANX2 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 7:122,018,937...122,032,009
Ensembl chr 7:122,018,937...122,032,004
|
|
| G
|
Paox
|
polyamine oxidase
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of PAOX mRNA
|
CTD |
PMID:15761015 |
|
NCBI chr 1:204,349,326...204,358,140
Ensembl chr 1:204,348,987...204,358,481
|
|
| G
|
Pappa
|
pappalysin 1
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of PAPPA mRNA
|
CTD |
PMID:22521957 |
|
NCBI chr 5:83,513,358...83,751,364
Ensembl chr 5:83,513,358...83,751,361
|
|
| G
|
Pappa2
|
pappalysin 2
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of PAPPA2 mRNA
|
CTD |
PMID:35676786 |
|
NCBI chr13:73,407,385...73,683,699
Ensembl chr13:73,407,385...73,681,568
|
|
| G
|
Papss1
|
3'-phosphoadenosine 5'-phosphosulfate synthase 1
|
multiple interactions decreases expression
|
ISO
|
[Arsenic Trioxide co-treated with Ascorbic Acid] results in decreased expression of PAPSS1 mRNA Arsenic Trioxide results in decreased expression of PAPSS1 mRNA
|
CTD |
PMID:25555879 |
|
NCBI chr 2:222,646,103...222,788,475
Ensembl chr 2:222,714,487...222,788,670
|
|
| G
|
Papss2
|
3'-phosphoadenosine 5'-phosphosulfate synthase 2
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of PAPSS2 mRNA
|
CTD |
PMID:22521957 |
|
NCBI chr 1:239,867,597...239,952,614
Ensembl chr 1:239,867,574...239,952,616
|
|
| G
|
Paqr6
|
progestin and adipoQ receptor family member 6
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of PAQR6 mRNA
|
CTD |
PMID:15725085 |
|
NCBI chr 2:176,131,345...176,136,266
Ensembl chr 2:176,131,859...176,136,265
|
|
| G
|
Pard3
|
par-3 family cell polarity regulator
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of PARD3 mRNA alternative form
|
CTD |
PMID:35676786 |
|
NCBI chr19:71,977,420...72,527,273
Ensembl chr19:71,977,470...72,526,941
|
|
| G
|
Parn
|
poly(A)-specific ribonuclease
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of PARN mRNA
|
CTD |
PMID:25258189 |
|
NCBI chr10:1,917,830...2,055,749
Ensembl chr10:1,917,830...2,055,722
|
|
| G
|
Parp1
|
poly (ADP-ribose) polymerase 1
|
increases expression multiple interactions increases degradation decreases expression increases activity increases cleavage affects localization
|
ISO EXP
|
Arsenic Trioxide results in increased expression of PARP1 protein; Arsenic Trioxide results in increased expression of PARP1 protein modified form 17-(dimethylaminoethylamino)-17-demethoxygeldanamycin promotes the reaction [Arsenic Trioxide results in increased cleavage of PARP1 protein]; 3,4-dihydro-5-(4-(1-piperidinyl)butoxy)-1(2H)-isoquinolinone inhibits the reaction [[Arsenic Trioxide co-treated with phytosphingosine] results in increased activity of PARP1 protein]; 6-Aminonicotinamide inhibits the reaction [Arsenic Trioxide results in increased cleavage of PARP1 protein]; [Arsenic Trioxide co-treated with apatinib] results in increased cleavage of PARP1 protein; [Arsenic Trioxide co-treated with Bortezomib] results in increased degradation of PARP1 protein; [Arsenic Trioxide co-treated with Ethacrynic Acid] results in increased cleavage of PARP1 protein; [Arsenic Trioxide co-treated with IL24 protein] results in decreased expression of PARP1; [Arsenic Trioxide co-treated with MIR15A co-treated with MIR16-1] results in increased cleavage of PARP1 protein; [Arsenic Trioxide co-treated with PD 173074] results in increased expression of PARP1 protein modified form; [Arsenic Trioxide co-treated with phytosphingosine] results in increased activity of PARP1 protein; [Arsenic Trioxide co-treated with phytosphingosine] results in increased cleavage of PARP1 protein; [Arsenic Trioxide co-treated with Plant Extracts] results in increased cleavage of PARP1 protein; [Arsenic Trioxide results in increased susceptibility to PD 173074] which results in increased expression of PARP1 protein modified form; [Dasatinib co-treated with Arsenic Trioxide] results in increased cleavage of PARP1 protein; [Genistein co-treated with Arsenic Trioxide] results in increased cleavage of PARP1 protein; [MARVELD1 protein results in decreased susceptibility to Arsenic Trioxide] which results in decreased cleavage of PARP1 protein; [monomethylarsonous acid co-treated with dimethylarsinous acid co-treated with Arsenic Trioxide] results in increased cleavage of PARP1 protein; [PD 173074 results in increased susceptibility to Arsenic Trioxide] which results in increased expression of PARP1 protein modified form; [pifithrin co-treated with Arsenic Trioxide] results in decreased expression of PARP1 protein; [pifithrin co-treated with Arsenic Trioxide] results in increased cleavage of PARP1 protein; [sulforaphane co-treated with Arsenic Trioxide] results in increased cleavage of PARP1 protein; [Sulindac co-treated with Arsenic Trioxide] results in increased cleavage of PARP1 protein; Acetylcysteine inhibits the reaction [[Arsenic Trioxide co-treated with Ethacrynic Acid] results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [[Arsenic Trioxide co-treated with phytosphingosine] results in increased activity of PARP1 protein]; Acetylcysteine inhibits the reaction [[monomethylarsonous acid co-treated with dimethylarsinous acid co-treated with Arsenic Trioxide] results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [[sulforaphane co-treated with Arsenic Trioxide] results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [[Sulindac co-treated with Arsenic Trioxide] results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide promotes the reaction [Cisplatin results in increased cleavage of PARP1 protein]]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased expression of PARP1 protein]; Acetylcysteine inhibits the reaction [Cisplatin promotes the reaction [Arsenic Trioxide results in increased cleavage of PARP1 protein]]; Arsenic Trioxide promotes the reaction [Chloroquine results in increased cleavage of PARP1 protein]; Arsenic Trioxide promotes the reaction [Cisplatin results in increased cleavage of PARP1 protein]; Arsenic Trioxide promotes the reaction [Curcumin results in increased expression of PARP1 protein modified form]; Arsenic Trioxide promotes the reaction [Dasatinib results in increased cleavage of PARP1 protein]; Arsenic Trioxide promotes the reaction [Matrines results in increased cleavage of PARP1 protein]; Arsenic Trioxide promotes the reaction [pralsetinib results in increased cleavage of PARP1 protein]; Arsenic Trioxide promotes the reaction [Zoledronic Acid results in increased cleavage of PARP1 protein]; Arsenic Trioxide results in increased cleavage of and results in increased activity of PARP1 protein; benzyloxycarbonyl-valyl-alanyl-aspartic acid analog inhibits the reaction [[Arsenic Trioxide co-treated with Ethacrynic Acid] results in increased cleavage of PARP1 protein]; benzyloxycarbonyl-valyl-alanyl-aspartic acid analog inhibits the reaction [[monomethylarsonous acid co-treated with dimethylarsinous acid co-treated with Arsenic Trioxide] results in increased cleavage of PARP1 protein]; benzyloxycarbonyl-valyl-alanyl-aspartic acid analog inhibits the reaction [Arsenic Trioxide results in increased cleavage of PARP1 protein]; Cisplatin promotes the reaction [Arsenic Trioxide results in increased cleavage of PARP1 protein]; Curcumin promotes the reaction [Arsenic Trioxide results in increased expression of PARP1 protein modified form]; Dasatinib promotes the reaction [Arsenic Trioxide results in increased cleavage of PARP1 protein]; Deoxyglucose inhibits the reaction [Arsenic Trioxide results in increased cleavage of PARP1 protein]; Dithiothreitol inhibits the reaction [Arsenic Trioxide results in increased cleavage of PARP1 protein]; GRB10 protein promotes the reaction [[Arsenic Trioxide co-treated with apatinib] results in increased cleavage of PARP1 protein]; GSTP1 mutant form promotes the reaction [[Arsenic Trioxide co-treated with Ethacrynic Acid] results in increased cleavage of PARP1 protein]; HSF1 protein affects the reaction [Arsenic Trioxide results in increased cleavage of PARP1 protein]; KNK 437 promotes the reaction [Arsenic Trioxide results in increased cleavage of PARP1 protein]; MARVELD1 protein inhibits the reaction [Arsenic Trioxide results in increased cleavage of PARP1 protein]; Matrines promotes the reaction [Arsenic Trioxide results in increased cleavage of PARP1 protein]; MCL1 mutant form promotes the reaction [[Arsenic Trioxide co-treated with Ethacrynic Acid] results in increased cleavage of PARP1 protein]; NCF2 mutant form inhibits the reaction [Arsenic Trioxide results in increased cleavage of PARP1 protein]; PRDX3 protein affects the reaction [Arsenic Trioxide results in increased cleavage of and results in increased activity of PARP1 protein]; pyrazolanthrone inhibits the reaction [[Arsenic Trioxide co-treated with Ethacrynic Acid] results in increased cleavage of PARP1 protein]; pyrazolanthrone inhibits the reaction [[Sulindac co-treated with Arsenic Trioxide] results in increased cleavage of PARP1 protein]; pyrazolanthrone inhibits the reaction [Arsenic Trioxide results in increased cleavage of PARP1 protein]; SB 203580 inhibits the reaction [Arsenic Trioxide results in increased cleavage of PARP1 protein]; TGIF1 mutant form promotes the reaction [Arsenic Trioxide results in increased cleavage of PARP1 protein]; TGIF1 protein inhibits the reaction [Arsenic Trioxide results in increased cleavage of PARP1 protein] Arsenic Trioxide results in increased degradation of PARP1 protein Arsenic Trioxide results in decreased expression of PARP1 protein Arsenic Trioxide results in increased activity of PARP1 protein Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased cleavage of PARP1 protein]; salvianolic acid A inhibits the reaction [Arsenic Trioxide results in increased expression of PARP1 protein] Arsenic Trioxide affects the localization of PARP1 protein modified form [Genistein co-treated with Arsenic Trioxide] results in increased cleavage of PARP1 protein; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased activity of PARP1 protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased cleavage of PARP1 protein]; Arsenic Trioxide promotes the reaction [Drugs, Chinese Herbal results in increased cleavage of PARP1 protein]; Deoxyglucose promotes the reaction [Metformin inhibits the reaction [Arsenic Trioxide results in increased expression of PARP1 protein modified form]]; Glucose deficiency inhibits the reaction [Arsenic Trioxide results in increased expression of PARP1 protein modified form]; Metformin inhibits the reaction [Arsenic Trioxide results in increased expression of PARP1 protein modified form]; Rotenone inhibits the reaction [Arsenic Trioxide results in increased expression of PARP1 protein modified form]
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CTD |
PMID:10382944 PMID:10477740 PMID:10648417 PMID:10850458 PMID:11146441 PMID:11304686 PMID:11739184 PMID:12148893 PMID:12181429 PMID:12429934 PMID:12883035 PMID:12883267 PMID:12931215 PMID:14632209 PMID:15131059 PMID:15314284 PMID:15493360 PMID:15761769 PMID:16166054 PMID:16328441 PMID:16646077 PMID:17237268 PMID:17495969 PMID:18022205 PMID:18281123 PMID:18539383 PMID:19364129 PMID:19371599 PMID:19408305 PMID:19468689 PMID:19695276 PMID:20435036 PMID:20723298 PMID:20953137 PMID:20977926 PMID:21056550 PMID:21078540 PMID:21454520 PMID:21565247 PMID:21594580 PMID:21649584 PMID:22496356 PMID:22532027 PMID:22922937 PMID:23082001 PMID:23700110 PMID:23861973 PMID:24157283 PMID:24634002 PMID:25174355 PMID:25246272 PMID:25419056 PMID:25574600 PMID:25791921 PMID:25972196 PMID:26160715 PMID:27430728 PMID:27794399 PMID:28391263 PMID:28587418 PMID:29095437 PMID:29266867 PMID:29767511 PMID:29774349 PMID:29944906 PMID:30338810 PMID:31205918 PMID:32096187 PMID:32305283 PMID:34303041 PMID:35030298 PMID:37301138 PMID:39223679 More...
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|
NCBI chr13:94,839,484...94,871,295
Ensembl chr13:94,839,433...94,871,567
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| G
|
Parp2
|
poly (ADP-ribose) polymerase 2
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of PARP2 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr15:26,494,722...26,517,893
Ensembl chr15:26,494,731...26,517,891
|
|
| G
|
Parp8
|
poly (ADP-ribose) polymerase family, member 8
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of PARP8 mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr 2:50,408,404...50,581,513
Ensembl chr 2:50,408,404...50,581,233
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|
| G
|
Patz1
|
POZ (BTB) and AT hook containing zinc finger 1
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of PATZ1 mRNA
|
CTD |
PMID:35676786 |
|
NCBI chr14:82,378,226...82,396,679
Ensembl chr14:82,377,697...82,396,686
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|
| G
|
Pawr
|
pro-apoptotic WT1 regulator
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of PAWR mRNA; Arsenic Trioxide results in increased expression of PAWR protein
|
CTD |
PMID:16966277 |
|
NCBI chr 7:45,531,480...45,611,492
Ensembl chr 7:45,531,637...45,611,492
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|
| G
|
Pax3
|
paired box 3
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of PAX3 mRNA
|
CTD |
PMID:35676786 |
|
NCBI chr 9:87,015,960...87,112,531
Ensembl chr 9:87,016,999...87,124,141
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|
| G
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Pax5
|
paired box 5
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of PAX5 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 5:63,554,784...63,741,380
Ensembl chr 5:63,560,722...63,739,987
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|
| G
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Pax6
|
paired box 6
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of PAX6 mRNA
|
CTD |
PMID:37969188 |
|
NCBI chr 3:112,590,034...112,611,771
Ensembl chr 3:112,590,391...112,611,763
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|
| G
|
Pax9
|
paired box 9
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of PAX9 mRNA
|
CTD |
PMID:26705709 |
|
NCBI chr 6:79,917,466...79,938,551
Ensembl chr 6:79,921,801...79,938,549
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|
| G
|
Pbrm1
|
polybromo 1
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of PBRM1 mRNA
|
CTD |
PMID:34108876 |
|
NCBI chr16:6,219,933...6,319,336
Ensembl chr16:6,219,917...6,319,336
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|
| G
|
Pbx3
|
PBX homeobox 3
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of PBX3 mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr 3:37,886,241...38,079,956
Ensembl chr 3:37,886,687...38,079,895
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|
| G
|
Pcbd1
|
pterin-4 alpha-carbinolamine dehydratase 1
|
decreases response to substance
|
ISO
|
PCBD1 protein results in decreased susceptibility to Arsenic Trioxide
|
CTD |
PMID:20707922 |
|
NCBI chr20:29,573,362...29,587,181
Ensembl chr20:29,573,423...29,587,180
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|
| G
|
Pcbp1
|
poly(rC) binding protein 1
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to PCBP1 protein]
|
CTD |
PMID:26598702 |
|
NCBI chr 4:120,530,100...120,532,107
Ensembl chr 4:120,529,172...120,539,111
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|
| G
|
Pcbp2
|
poly(rC) binding protein 2
|
decreases expression increases expression multiple interactions
|
ISO
|
Arsenic Trioxide results in decreased expression of PCBP2 protein Arsenic Trioxide results in increased expression of PCBP2 mRNA Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to PCBP2 protein]
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CTD |
PMID:20458559 PMID:25419056 PMID:26598702 |
|
NCBI chr 7:135,483,702...135,508,254
Ensembl chr 7:135,483,856...135,509,412
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|
| G
|
Pcca
|
propionyl-CoA carboxylase subunit alpha
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of PCCA mRNA
|
CTD |
PMID:22521957 |
|
NCBI chr15:106,034,586...106,374,908
Ensembl chr15:106,034,610...106,374,908
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|
| G
|
Pcdh17
|
protocadherin 17
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to PCDH17 protein]
|
CTD |
PMID:26598702 |
|
NCBI chr15:66,631,549...66,725,007
Ensembl chr15:66,633,142...66,722,105
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|
| G
|
Pcdh19
|
protocadherin 19
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of PCDH19 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr X:101,061,002...101,166,777
Ensembl chr X:101,065,263...101,165,269
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|
| G
|
Pcdh20
|
protocadherin 20
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of PCDH20 mRNA
|
CTD |
PMID:26705709 |
|
NCBI chr15:70,834,042...70,840,298
Ensembl chr15:70,834,042...70,840,298
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|
| G
|
Pcdhac1
|
protocadherin alpha subfamily C, 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of PCDHAC1 mRNA
|
CTD |
PMID:39716349 |
|
|
|
| G
|
Pcf11
|
PCF11 cleavage and polyadenylation factor subunit
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of PCF11 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 1:156,109,724...156,136,950
Ensembl chr 1:156,109,724...156,136,435
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|
| G
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Pcgf6
|
polycomb group ring finger 6
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of PCGF6 mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr 1:255,866,709...255,886,306
Ensembl chr 1:255,866,711...255,886,266
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|
| G
|
Pck1
|
phosphoenolpyruvate carboxykinase 1
|
increases expression multiple interactions decreases expression
|
ISO
|
Arsenic Trioxide results in increased expression of PCK1 mRNA Taurine inhibits the reaction [Arsenic Trioxide results in increased expression of PCK1 mRNA] Arsenic Trioxide results in increased expression of PCK1 protein Arsenic Trioxide results in decreased expression of PCK1 mRNA
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CTD |
PMID:30362509 PMID:33634982 PMID:35226250 PMID:39716349 |
|
NCBI chr 3:182,348,572...182,354,521
Ensembl chr 3:182,348,572...182,354,561
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|
| G
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Pck2
|
phosphoenolpyruvate carboxykinase 2 (mitochondrial)
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of PCK2 protein
|
CTD |
PMID:19364129 |
|
NCBI chr15:32,997,853...33,006,691
Ensembl chr15:32,997,834...33,016,864
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| G
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Pcm1
|
pericentriolar material 1
|
increases response to substance decreases expression
|
ISO
|
PCM1 protein results in increased susceptibility to Arsenic Trioxide Arsenic Trioxide results in decreased expression of PCM1 mRNA
|
CTD |
PMID:20707922 PMID:22521957 |
|
NCBI chr16:57,711,833...57,808,842
Ensembl chr16:57,711,833...57,808,599
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|
| G
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Pcna
|
proliferating cell nuclear antigen
|
decreases expression increases expression multiple interactions
|
ISO EXP
|
Arsenic Trioxide results in decreased expression of PCNA protein Arsenic Trioxide results in increased expression of PCNA mRNA Arsenic Trioxide results in decreased expression of PCNA mRNA; Arsenic Trioxide results in decreased expression of PCNA protein Arsenic Trioxide promotes the reaction [CDKN1A protein binds to PCNA protein] pifithrin inhibits the reaction [Arsenic Trioxide results in increased expression of PCNA mRNA]
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CTD |
PMID:12783709 PMID:16029599 PMID:17390014 PMID:17487067 PMID:21565247 PMID:34413873 More...
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|
NCBI chr 3:139,951,948...139,955,820
Ensembl chr 3:139,951,941...139,955,901
|
|
| G
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Pcolce
|
procollagen C-endopeptidase enhancer
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of PCOLCE mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr12:24,720,972...24,727,287
Ensembl chr12:24,720,936...24,727,287
|
|
| G
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Pcolce2
|
procollagen C-endopeptidase enhancer 2
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of PCOLCE2 mRNA
|
CTD |
PMID:26705709 |
|
NCBI chr 8:105,073,086...105,130,725
Ensembl chr 8:105,073,086...105,145,160
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|
| G
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Pcsk1
|
proprotein convertase subtilisin/kexin type 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of PCSK1 mRNA
|
CTD |
PMID:21461292 |
|
NCBI chr 2:6,130,045...6,176,974
Ensembl chr 2:6,129,592...6,176,974
|
|
| G
|
Pcsk5
|
proprotein convertase subtilisin/kexin type 5
|
increases expression decreases expression
|
ISO
|
Arsenic Trioxide results in increased expression of PCSK5 mRNA Arsenic Trioxide results in decreased expression of PCSK5 mRNA
|
CTD |
PMID:15761015 PMID:37969188 |
|
NCBI chr 1:224,263,823...224,694,350
Ensembl chr 1:224,264,678...224,694,347
|
|
| G
|
Pcsk7
|
proprotein convertase subtilisin/kexin type 7
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to PCSK7 protein]
|
CTD |
PMID:26598702 |
|
NCBI chr 8:55,098,821...55,121,416
Ensembl chr 8:55,098,806...55,121,382
|
|
| G
|
Pcsk9
|
proprotein convertase subtilisin/kexin type 9
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of PCSK9 mRNA
|
CTD |
PMID:26705709 |
|
NCBI chr 5:126,440,102...126,462,507
Ensembl chr 5:126,440,102...126,462,507
|
|
| G
|
Pcyt2
|
phosphate cytidylyltransferase 2, ethanolamine
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of PCYT2 mRNA
|
CTD |
PMID:27829220 |
|
NCBI chr10:106,387,150...106,394,500
Ensembl chr10:106,387,148...106,394,468
|
|
| G
|
Pdcd2
|
programmed cell death 2
|
multiple interactions increases expression
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to PDCD2 protein] Arsenic Trioxide results in increased expression of PDCD2 mRNA
|
CTD |
PMID:20458559 PMID:26598702 |
|
NCBI chr 1:65,158,034...65,163,524
Ensembl chr 1:65,158,034...65,163,524
|
|
| G
|
Pdcd4
|
programmed cell death 4
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of PDCD4 mRNA; Arsenic Trioxide results in increased expression of PDCD4 protein
|
CTD |
PMID:17259349 PMID:20458559 PMID:24356939 PMID:25419056 PMID:30093655 |
|
NCBI chr 1:262,912,659...262,949,581
Ensembl chr 1:262,926,656...262,950,189
|
|
| G
|
Pdcd5
|
programmed cell death 5
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of PDCD5 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 1:97,442,755...97,448,084
Ensembl chr 1:97,442,755...97,449,844
|
|
| G
|
Pdcd6ip
|
programmed cell death 6 interacting protein
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of PDCD6IP mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr 8:122,469,223...122,524,993
Ensembl chr 8:122,469,223...122,524,993
|
|
| G
|
Pdcl3
|
phosducin-like 3
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of PDCL3 protein
|
CTD |
PMID:30093655 |
|
NCBI chr 9:48,730,083...48,738,554
Ensembl chr 9:48,723,767...48,739,529
|
|
| G
|
Pde1a
|
phosphodiesterase 1A
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of PDE1A mRNA
|
CTD |
PMID:26705709 |
|
NCBI chr 3:85,152,053...85,432,289
Ensembl chr 3:85,154,184...85,519,212
|
|
| G
|
Pde2a
|
phosphodiesterase 2A
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of PDE2A mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 1:165,235,623...165,327,466
Ensembl chr 1:165,235,623...165,327,466
|
|
| G
|
Pde4a
|
phosphodiesterase 4A
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of PDE4A mRNA
|
CTD |
PMID:15070760 |
|
NCBI chr 8:27,966,978...28,029,721
Ensembl chr 8:27,966,996...28,046,924
|
|
| G
|
Pde4b
|
phosphodiesterase 4B
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of PDE4B mRNA
|
CTD |
PMID:15761015 |
|
NCBI chr 5:122,028,956...122,598,267
Ensembl chr 5:122,135,174...122,598,267
|
|
| G
|
Pde4d
|
phosphodiesterase 4D
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of PDE4D mRNA
|
CTD |
PMID:22521957 |
|
NCBI chr 2:41,748,337...43,262,567
Ensembl chr 2:42,110,838...43,262,569
|
|
| G
|
Pde4dip
|
phosphodiesterase 4D interacting protein
|
increases expression multiple interactions
|
ISO
|
Arsenic Trioxide results in increased expression of PDE4DIP mRNA [Tretinoin co-treated with Arsenic Trioxide] affects the expression of PDE4DIP mRNA
|
CTD |
PMID:15761015 PMID:15894607 |
|
NCBI chr 2:187,982,002...188,178,937
Ensembl chr 2:187,981,878...188,178,869
|
|
| G
|
Pde7b
|
phosphodiesterase 7B
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of PDE7B mRNA
|
CTD |
PMID:26705709 |
|
NCBI chr 1:16,994,072...17,312,828
Ensembl chr 1:17,002,286...17,312,456
|
|
| G
|
Pde8a
|
phosphodiesterase 8A
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of PDE8A mRNA
|
CTD |
PMID:22521957 |
|
NCBI chr 1:144,575,203...144,698,216
Ensembl chr 1:144,575,428...144,698,215
|
|
| G
|
Pdgfa
|
platelet derived growth factor subunit A
|
decreases expression increases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of PDGFA mRNA Arsenic Trioxide results in increased expression of PDGFA mRNA
|
CTD |
PMID:20458559 PMID:27829220 |
|
NCBI chr12:20,759,366...20,780,337
Ensembl chr12:20,754,208...20,780,322
|
|
| G
|
Pdgfb
|
platelet derived growth factor subunit B
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [PDGFB protein results in increased expression of CCNA1 protein]; Arsenic Trioxide inhibits the reaction [PDGFB protein results in increased expression of CDK2 protein]; Arsenic Trioxide inhibits the reaction [PDGFB protein results in increased expression of CDK4 protein]
|
CTD |
PMID:35276128 |
|
NCBI chr 7:113,419,882...113,438,343
Ensembl chr 7:113,420,710...113,438,343
|
|
| G
|
Pdgfrb
|
platelet derived growth factor receptor beta
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of PDGFRB mRNA
|
CTD |
PMID:29633893 |
|
NCBI chr18:56,770,348...56,809,228
Ensembl chr18:56,770,348...56,809,233
|
|
| G
|
Pdha1
|
pyruvate dehydrogenase E1 subunit alpha 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of PDHA1 mRNA
|
CTD |
PMID:22521957 |
|
NCBI chr X:38,509,158...38,522,986
Ensembl chr X:38,509,084...38,522,536
|
|
| G
|
Pdia3
|
protein disulfide isomerase family A, member 3
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of PDIA3 protein
|
CTD |
PMID:19364129 |
|
NCBI chr 3:128,841,781...128,865,733
Ensembl chr 3:128,841,917...128,867,327
|
|
| G
|
Pdk1
|
pyruvate dehydrogenase kinase 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of PDK1 mRNA
|
CTD |
PMID:32112876 |
|
NCBI chr 3:77,113,464...77,144,145
Ensembl chr 3:77,113,473...77,144,145
|
|
| G
|
Pdk3
|
pyruvate dehydrogenase kinase 3
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of PDK3 mRNA
|
CTD |
PMID:34108876 |
|
NCBI chr X:62,480,535...62,547,371
Ensembl chr X:62,480,535...62,547,371
|
|
| G
|
Pdlim5
|
PDZ and LIM domain 5
|
decreases expression affects expression
|
ISO
|
Arsenic Trioxide results in decreased expression of PDLIM5 mRNA Arsenic Trioxide affects the expression of PDLIM5 mRNA
|
CTD |
PMID:20458559 PMID:39716349 |
|
NCBI chr 2:233,625,478...233,793,582
Ensembl chr 2:233,628,503...233,793,528
|
|
| G
|
Pdlim7
|
PDZ and LIM domain 7
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of PDLIM7 mRNA
|
CTD |
PMID:15761015 |
|
NCBI chr17:9,129,603...9,144,956
Ensembl chr17:9,129,525...9,144,956
|
|
| G
|
Pdpk1
|
3-phosphoinositide dependent protein kinase-1
|
decreases expression decreases activity increases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of PDPK1 mRNA Arsenic Trioxide results in decreased activity of PDPK1 protein Arsenic Trioxide results in increased expression of PDPK1 mRNA
|
CTD |
PMID:14633726 PMID:30032600 PMID:32781346 |
|
NCBI chr10:13,610,000...13,687,226
Ensembl chr10:13,610,063...13,679,181
|
|
| G
|
Pdrg1
|
p53 and DNA damage regulated 1
|
multiple interactions increases expression
|
ISO
|
Metformin inhibits the reaction [Arsenic Trioxide results in increased expression of PDRG1 mRNA]
|
CTD |
PMID:29095437 |
|
NCBI chr 3:161,937,812...161,943,981
Ensembl chr 3:161,937,815...161,948,995
|
|
| G
|
Pdxdc1
|
pyridoxal-dependent decarboxylase domain containing 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of PDXDC1 mRNA
|
CTD |
PMID:22521957 |
|
NCBI chr10:2,528,989...2,620,669
Ensembl chr10:2,532,485...2,620,669
|
|
| G
|
Pdzd2
|
PDZ domain containing 2
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of PDZD2 mRNA
|
CTD |
PMID:15761015 |
|
NCBI chr 2:63,111,650...63,497,520
Ensembl chr 2:63,111,650...63,497,478
|
|
| G
|
Pdzd7
|
PDZ domain containing 7
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of PDZD7 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 1:253,837,454...253,856,919
Ensembl chr 1:253,837,459...253,855,999
|
|
| G
|
Pdzd8
|
PDZ domain containing 8
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of PDZD8 mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr 1:268,435,304...268,492,923
Ensembl chr 1:268,435,304...268,492,913
|
|
| G
|
Pdzrn4
|
PDZ domain containing RING finger 4
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of PDZRN4 mRNA
|
CTD |
PMID:26705709 |
|
NCBI chr 7:125,696,448...125,844,965
Ensembl chr 7:125,696,448...125,844,965
|
|
| G
|
Pecam1
|
platelet and endothelial cell adhesion molecule 1
|
increases expression multiple interactions decreases expression
|
ISO EXP
|
Arsenic Trioxide results in increased expression of PECAM1 mRNA [Tretinoin co-treated with Arsenic Trioxide] results in increased expression of PECAM1 mRNA; Diosgenin inhibits the reaction [Arsenic Trioxide results in decreased expression of PECAM1 protein]; NR3C1 promotes the reaction [Diosgenin inhibits the reaction [Arsenic Trioxide results in decreased expression of PECAM1 protein]] Arsenic Trioxide results in decreased expression of PECAM1 mRNA; Arsenic Trioxide results in decreased expression of PECAM1 protein
|
CTD |
PMID:15761015 PMID:15894607 PMID:30014256 PMID:39059093 |
|
NCBI chr10:92,090,263...92,152,002
Ensembl chr10:92,090,235...92,151,839
|
|
| G
|
Peli1
|
pellino E3 ubiquitin protein ligase 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of PELI1 mRNA
|
CTD |
PMID:24356939 |
|
NCBI chr14:99,455,970...99,510,474
Ensembl chr14:99,455,811...99,510,466
|
|
| G
|
Per2
|
period circadian regulator 2
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of PER2 mRNA
|
CTD |
PMID:20458559 PMID:26705709 PMID:27829220 |
|
NCBI chr 9:99,454,828...99,497,069
Ensembl chr 9:99,454,830...99,496,993
|
|
| G
|
Pex3
|
peroxisomal biogenesis factor 3
|
increases expression multiple interactions
|
ISO
|
Arsenic Trioxide results in increased expression of PEX3 mRNA [Tretinoin co-treated with Arsenic Trioxide] results in decreased expression of PEX3 mRNA
|
CTD |
PMID:15761015 PMID:15894607 |
|
NCBI chr 1:9,732,641...9,774,479
Ensembl chr 1:9,732,492...9,774,576
|
|
| G
|
Pfas
|
phosphoribosylformylglycinamidine synthase
|
increases expression multiple interactions
|
ISO
|
Arsenic Trioxide results in increased expression of PFAS mRNA [Arsenic Trioxide co-treated with Ascorbic Acid] results in increased expression of PFAS mRNA
|
CTD |
PMID:25555879 |
|
NCBI chr10:54,189,157...54,210,685
Ensembl chr10:54,189,157...54,207,272
|
|
| G
|
Pfkfb4
|
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of PFKFB4 mRNA
|
CTD |
PMID:27829220 |
|
NCBI chr 8:118,522,371...118,565,478
Ensembl chr 8:118,522,365...118,565,468
|
|
| G
|
Pfkm
|
phosphofructokinase, muscle
|
decreases expression multiple interactions
|
ISO
|
Arsenic Trioxide results in decreased expression of PFKM mRNA; Arsenic Trioxide results in decreased expression of PFKM protein [Ascorbic Acid co-treated with Arsenic Trioxide] results in decreased expression of PFKM protein; Arsenic Trioxide promotes the reaction [Ascorbic Acid results in decreased expression of PFKM mRNA]; Arsenic Trioxide promotes the reaction [Ascorbic Acid results in decreased expression of PFKM protein]; Ascorbic Acid promotes the reaction [Arsenic Trioxide results in decreased expression of PFKM mRNA]; Ascorbic Acid promotes the reaction [Arsenic Trioxide results in decreased expression of PFKM protein]
|
CTD |
PMID:38160894 |
|
NCBI chr 7:131,100,684...131,138,250
Ensembl chr 7:131,100,753...131,138,248
|
|
| G
|
Pfkp
|
phosphofructokinase, platelet
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of PFKP protein
|
CTD |
PMID:25419056 |
|
NCBI chr17:68,639,749...68,704,055
Ensembl chr17:68,639,481...68,705,752
|
|
| G
|
Pfn2
|
profilin 2
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to PFN2 protein]
|
CTD |
PMID:26598702 |
|
NCBI chr 2:144,217,100...144,222,936
Ensembl chr 2:144,205,636...144,222,936
|
|
| G
|
Pfn4
|
profilin family, member 4
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to PFN4 protein]
|
CTD |
PMID:26598702 |
|
NCBI chr 6:33,506,077...33,516,163
Ensembl chr 6:33,506,077...33,516,163
|
|
| G
|
Pgam5
|
PGAM family member 5, mitochondrial serine/threonine protein phosphatase
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of PGAM5 protein
|
CTD |
PMID:25419056 |
|
NCBI chr12:52,069,023...52,076,131
Ensembl chr12:52,069,103...52,076,131
|
|
| G
|
Pgc
|
progastricsin
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of PGC mRNA
|
CTD |
PMID:17547211 |
|
NCBI chr 9:20,755,002...20,763,220
Ensembl chr 9:20,755,002...20,763,220
|
|
| G
|
Pgd
|
phosphogluconate dehydrogenase
|
decreases response to substance multiple interactions increases expression
|
ISO
|
PGD protein results in decreased susceptibility to Arsenic Trioxide [Tretinoin co-treated with Arsenic Trioxide] results in increased expression of PGD mRNA; Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to PGD protein] Arsenic Trioxide results in increased expression of PGD mRNA
|
CTD |
PMID:15894607 PMID:20458559 PMID:20707922 PMID:25258189 PMID:26598702 |
|
NCBI chr 5:164,865,830...164,882,029
Ensembl chr 5:164,865,830...164,882,029
|
|
| G
|
Pgf
|
placental growth factor
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of PGF mRNA
|
CTD |
PMID:17547211 |
|
NCBI chr 6:110,547,165...110,557,747
Ensembl chr 6:110,547,153...110,557,747
|
|
| G
|
Pgghg
|
protein-glucosylgalactosylhydroxylysine glucosidase
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of PGGHG mRNA
|
CTD |
PMID:25258189 |
|
NCBI chr 1:205,467,179...205,474,185
Ensembl chr 1:205,467,993...205,474,183
|
|
| G
|
Pggt1b
|
protein geranylgeranyltransferase type I subunit beta
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of PGGT1B mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr18:41,138,536...41,182,145
Ensembl chr18:41,139,965...41,182,139
|
|
| G
|
Pgk1
|
phosphoglycerate kinase 1
|
increases expression multiple interactions decreases expression
|
ISO
|
Arsenic Trioxide results in increased expression of PGK1 mRNA [Ascorbic Acid co-treated with Arsenic Trioxide] results in decreased expression of PGK1 protein; Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to PGK1 protein]; Arsenic Trioxide promotes the reaction [Ascorbic Acid results in decreased expression of PGK1 mRNA]; Arsenic Trioxide promotes the reaction [Ascorbic Acid results in decreased expression of PGK1 protein]; Ascorbic Acid promotes the reaction [Arsenic Trioxide results in decreased expression of PGK1 mRNA]; Ascorbic Acid promotes the reaction [Arsenic Trioxide results in decreased expression of PGK1 protein] Arsenic Trioxide results in decreased expression of PGK1 mRNA; Arsenic Trioxide results in decreased expression of PGK1 protein
|
CTD |
PMID:22521957 PMID:26598702 PMID:38160894 |
|
NCBI chr X:75,336,988...75,352,962
Ensembl chr X:75,336,687...75,352,959
|
|
| G
|
Pgm1
|
phosphoglucomutase 1
|
increases expression multiple interactions decreases expression
|
ISO
|
Arsenic Trioxide results in increased expression of PGM1 mRNA; Arsenic Trioxide results in increased expression of PGM1 protein [Ascorbic Acid co-treated with Arsenic Trioxide] results in decreased expression of PGM1 protein; Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to PGM1 protein]; Arsenic Trioxide promotes the reaction [Ascorbic Acid results in decreased expression of PGM1 mRNA]; Arsenic Trioxide promotes the reaction [Ascorbic Acid results in decreased expression of PGM1 protein]; Ascorbic Acid promotes the reaction [Arsenic Trioxide results in decreased expression of PGM1 mRNA]; Ascorbic Acid promotes the reaction [Arsenic Trioxide results in decreased expression of PGM1 protein] Arsenic Trioxide results in decreased expression of PGM1 mRNA; Arsenic Trioxide results in decreased expression of PGM1 protein
|
CTD |
PMID:20458559 PMID:25419056 PMID:26598702 PMID:38160894 |
|
NCBI chr 5:119,710,734...119,770,159
Ensembl chr 5:119,710,737...119,770,159
|
|
| G
|
Pgm2
|
phosphoglucomutase 2
|
decreases expression increases expression multiple interactions
|
ISO
|
Arsenic Trioxide results in decreased expression of PGM2 mRNA Arsenic Trioxide results in increased expression of PGM2 protein Metformin inhibits the reaction [Arsenic Trioxide results in decreased expression of PGM2 mRNA]
|
CTD |
PMID:25419056 PMID:29095437 |
|
NCBI chr14:44,519,906...44,553,420
Ensembl chr14:44,519,906...44,553,770
|
|
| G
|
Pgm3
|
phosphoglucomutase 3
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to PGM3 protein]
|
CTD |
PMID:26598702 |
|
NCBI chr 8:96,398,331...96,416,045
Ensembl chr 8:96,398,269...96,416,021
|
|
| G
|
Phb1
|
prohibitin 1
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to PHB1 protein]
|
CTD |
PMID:26598702 |
|
NCBI chr10:81,102,043...81,114,815
Ensembl chr10:81,102,028...81,116,233
|
|
| G
|
Phf1
|
PHD finger protein 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of PHF1 mRNA
|
CTD |
PMID:25258189 |
|
NCBI chr20:5,019,650...5,024,732
Ensembl chr20:5,019,673...5,024,731
|
|
| G
|
Phf12
|
PHD finger protein 12
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of PHF12 mRNA
|
CTD |
PMID:21461292 |
|
NCBI chr10:63,368,547...63,417,079
Ensembl chr10:63,370,210...63,417,073
|
|
| G
|
Phf21a
|
PHD finger protein 21A
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of PHF21A mRNA
|
CTD |
PMID:20458559 PMID:22521957 |
|
NCBI chr 3:98,600,933...98,791,132
Ensembl chr 3:98,613,844...98,787,350
|
|
| G
|
Phf5a
|
PHD finger protein 5A
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of PHF5A protein
|
CTD |
PMID:25419056 |
|
NCBI chr 7:115,258,609...115,265,174
Ensembl chr 7:115,258,609...115,265,174
|
|
| G
|
Phgdh
|
phosphoglycerate dehydrogenase
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to PHGDH protein]
|
CTD |
PMID:26598702 |
|
NCBI chr 2:188,595,700...188,624,789
Ensembl chr 2:188,595,700...188,624,789
|
|
| G
|
Phkg2
|
phosphorylase kinase catalytic subunit gamma 2
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of PHKG2 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 1:191,614,738...191,627,615
Ensembl chr 1:191,614,865...191,627,616
|
|
| G
|
Phlda1
|
pleckstrin homology-like domain, family A, member 1
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of PHLDA1 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 7:48,853,690...48,855,894
Ensembl chr 7:48,853,260...48,857,542
|
|
| G
|
Phlda2
|
pleckstrin homology-like domain, family A, member 2
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of PHLDA2 mRNA
|
CTD |
PMID:15761015 |
|
NCBI chr 1:208,126,302...208,127,241
Ensembl chr 1:208,126,302...208,127,920
|
|
| G
|
Phlda3
|
pleckstrin homology-like domain, family A, member 3
|
increases expression multiple interactions
|
ISO
|
Arsenic Trioxide results in increased expression of PHLDA3 mRNA Metformin inhibits the reaction [Arsenic Trioxide results in increased expression of PHLDA3 mRNA]
|
CTD |
PMID:29095437 |
|
NCBI chr13:49,745,003...49,748,088
Ensembl chr13:49,742,591...49,749,621
|
|
| G
|
Phldb1
|
pleckstrin homology-like domain, family B, member 1
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of PHLDB1 mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr 8:53,900,338...53,948,325
Ensembl chr 8:53,900,338...53,949,518
|
|
| G
|
Phldb2
|
pleckstrin homology-like domain, family B, member 2
|
increases expression decreases expression
|
ISO
|
Arsenic Trioxide results in increased expression of PHLDB2 mRNA Arsenic Trioxide results in decreased expression of PHLDB2 mRNA
|
CTD |
PMID:20458559 PMID:39716349 |
|
NCBI chr11:68,321,738...68,540,724
Ensembl chr11:68,355,959...68,540,734
|
|
| G
|
Phlpp1
|
PH domain and leucine rich repeat protein phosphatase 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of PHLPP1 mRNA
|
CTD |
PMID:29633893 |
|
NCBI chr13:22,823,132...23,045,619
Ensembl chr13:22,823,132...23,045,619
|
|
| G
|
Phospho2
|
phosphatase, orphan 2
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to PHOSPHO2 protein]
|
CTD |
PMID:26598702 |
|
NCBI chr 3:74,962,649...74,969,810
Ensembl chr 3:74,962,361...74,970,892
|
|
| G
|
Phox2b
|
paired-like homeobox 2b
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of PHOX2B protein
|
CTD |
PMID:35467087 |
|
NCBI chr14:41,420,011...41,424,527
Ensembl chr14:41,420,011...41,424,494
|
|
| G
|
Phyhipl
|
phytanoyl-CoA 2-hydroxylase interacting protein-like
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to PHYHIPL protein]
|
CTD |
PMID:26598702 |
|
NCBI chr20:18,023,831...18,064,903
Ensembl chr20:17,934,683...18,065,756
|
|
| G
|
Pi4k2a
|
phosphatidylinositol 4-kinase type 2 alpha
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of PI4K2A protein
|
CTD |
PMID:30093655 |
|
NCBI chr 1:250,850,440...250,878,399
Ensembl chr 1:250,852,154...250,881,811
|
|
| G
|
Pi4ka
|
phosphatidylinositol 4-kinase alpha
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of PI4KA mRNA
|
CTD |
PMID:12852829 |
|
NCBI chr11:97,113,390...97,234,374
Ensembl chr11:97,113,245...97,228,315
|
|
| G
|
Pias1
|
protein inhibitor of activated STAT, 1
|
multiple interactions
|
ISO
|
PIAS1 protein promotes the reaction [Arsenic Trioxide results in increased degradation of PML protein]
|
CTD |
PMID:22406621 |
|
NCBI chr 8:72,233,566...72,347,085
Ensembl chr 8:72,233,566...72,334,315
|
|
| G
|
Pias2
|
protein inhibitor of activated STAT, 2
|
multiple interactions decreases expression
|
ISO
|
Metformin inhibits the reaction [Arsenic Trioxide results in decreased expression of PIAS2 mRNA]
|
CTD |
PMID:29095437 |
|
NCBI chr18:72,883,008...72,989,486
Ensembl chr18:72,882,890...73,006,662
|
|
| G
|
Pigh
|
phosphatidylinositol glycan anchor biosynthesis, class H
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to PIGH protein]
|
CTD |
PMID:26598702 |
|
NCBI chr 6:103,601,369...103,630,214
Ensembl chr 6:103,601,520...103,630,159
|
|
| G
|
Pigo
|
phosphatidylinositol glycan anchor biosynthesis, class O
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of PIGO mRNA
|
CTD |
PMID:15761015 |
|
NCBI chr 5:62,040,979...62,052,067
Ensembl chr 5:62,037,308...62,052,075
|
|
| G
|
Pigr
|
polymeric immunoglobulin receptor
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of PIGR mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr13:44,851,001...44,879,143
Ensembl chr13:44,851,182...44,879,141
|
|
| G
|
Pik3c3
|
phosphatidylinositol 3-kinase, catalytic subunit type 3
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of PIK3C3 protein
|
CTD |
PMID:34042274 |
|
NCBI chr18:22,119,677...22,203,546
Ensembl chr18:22,119,792...22,203,539
|
|
| G
|
Pik3ca
|
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of PIK3CA mRNA; Arsenic Trioxide results in decreased expression of PIK3CA protein
|
CTD |
PMID:20458559 PMID:34042274 |
|
NCBI chr 2:117,103,643...117,177,411
Ensembl chr 2:117,143,468...117,177,411
|
|
| G
|
Pik3cb
|
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of PIK3CB protein
|
CTD |
PMID:34042274 |
|
NCBI chr 8:108,474,017...108,579,140
Ensembl chr 8:108,474,019...108,579,331
|
|
| G
|
Pik3cg
|
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of PIK3CG protein
|
CTD |
PMID:34042274 |
|
NCBI chr 6:54,494,247...54,529,563
Ensembl chr 6:54,478,603...54,529,509
|
|
| G
|
Pik3r1
|
phosphoinositide-3-kinase regulatory subunit 1
|
decreases expression increases expression increases phosphorylation multiple interactions
|
ISO EXP
|
Arsenic Trioxide results in decreased expression of PIK3R1 mRNA Arsenic Trioxide results in increased expression of PIK3R1 mRNA Arsenic Trioxide results in decreased expression of PIK3R1 protein modified form Arsenic Trioxide results in increased phosphorylation of PIK3R1 protein dapagliflozin inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of PIK3R1 protein]
|
CTD |
PMID:30032600 PMID:30225639 PMID:32112876 PMID:34042274 PMID:38070468 |
|
NCBI chr 2:34,612,946...34,697,660
Ensembl chr 2:34,612,946...34,626,347
|
|
| G
|
Pik3r2
|
phosphoinositide-3-kinase regulatory subunit 2
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of PIK3R2 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr16:18,699,389...18,708,045
Ensembl chr16:18,699,448...18,709,665
|
|
| G
|
Pilra
|
paired immunoglobin-like type 2 receptor alpha
|
multiple interactions increases expression
|
ISO
|
Metformin inhibits the reaction [Arsenic Trioxide results in increased expression of PILRA mRNA]
|
CTD |
PMID:29095437 |
|
NCBI chr12:23,452,626...23,464,772
|
|
| G
|
Pilral1
|
paired immunoglobin-like type 2 receptor alpha like 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of ZNF37A mRNA
|
CTD |
PMID:15761015 |
|
NCBI chr12:23,409,774...23,421,574
|
|
| G
|
Pim1
|
Pim-1 proto-oncogene, serine/threonine kinase
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of PIM1 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr20:7,556,496...7,560,747
Ensembl chr20:7,556,113...7,561,764
|
|
| G
|
Pin1
|
peptidylprolyl cis/trans isomerase, NIMA-interacting 1
|
multiple interactions affects binding affects response to substance decreases expression
|
ISO
|
[Arsenic Trioxide binds to PIN1 protein] affects the reaction [Arsenic Trioxide results in decreased expression of CTNNB1 protein]; [Arsenic Trioxide binds to PIN1 protein] affects the reaction [Arsenic Trioxide results in decreased expression of FBXW7 protein]; [Arsenic Trioxide binds to PIN1 protein] affects the reaction [Arsenic Trioxide results in decreased expression of RAB2A protein]; [Arsenic Trioxide binds to PIN1 protein] affects the reaction [Arsenic Trioxide results in decreased expression of RELA protein]; [Arsenic Trioxide co-treated with NVP-BKM120] results in decreased expression of PIN1 mRNA; [Arsenic Trioxide co-treated with Tretinoin] results in decreased expression of PIN1 protein; AQP9 protein affects the reaction [Arsenic Trioxide promotes the reaction [Tretinoin results in decreased expression of and results in increased degradation of PIN1 protein]]; AQP9 protein affects the reaction [PIN1 protein affects the susceptibility to Arsenic Trioxide]; AQP9 protein affects the reaction [Tretinoin promotes the reaction [Arsenic Trioxide results in decreased expression of and results in increased degradation of PIN1 protein]]; Arsenic Trioxide promotes the reaction [Tretinoin results in decreased expression of and results in increased degradation of PIN1 protein]; Arsenic Trioxide results in decreased expression of and results in increased degradation of PIN1 protein; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Arsenic Trioxide results in decreased expression of PIN1 protein]; PIN1 protein affects the reaction [Arsenic Trioxide results in decreased expression of CTNNB1 protein]; PIN1 protein affects the reaction [Arsenic Trioxide results in decreased expression of RAB2A protein]; PIN1 protein affects the reaction [Arsenic Trioxide results in decreased expression of RELA protein]; PIN1 protein affects the reaction [Arsenic Trioxide results in increased expression of FBXW7 protein]; Tretinoin promotes the reaction [Arsenic Trioxide results in decreased expression of and results in increased degradation of PIN1 protein]; Tretinoin promotes the reaction [Arsenic Trioxide results in increased degradation of PIN1 protein] Arsenic Trioxide analog binds to PIN1 protein
|
CTD |
PMID:30093655 PMID:31539632 |
|
NCBI chr 8:27,465,538...27,477,016
|
|
| G
|
Pink1
|
PTEN induced kinase 1
|
multiple interactions increases expression decreases expression
|
EXP ISO
|
Taurine inhibits the reaction [Arsenic Trioxide results in decreased expression of PINK1 protein] Arsenic Trioxide results in increased expression of PINK1 protein 3-(2,4-dichloro-5-methoxyphenyl)-2-sulfanyl-4(3H)-quinazolinone inhibits the reaction [Arsenic Trioxide results in increased expression of PINK1 protein]; Cyclosporine inhibits the reaction [Arsenic Trioxide results in increased expression of PINK1 protein]
|
CTD |
PMID:27318970 PMID:30551535 |
|
NCBI chr 5:155,813,838...155,825,950
Ensembl chr 5:155,813,838...155,825,950
|
|
| G
|
Pinx1
|
PIN2/TERF1 interacting, telomerase inhibitor 1
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of PINX1 mRNA
|
CTD |
PMID:22944098 |
|
NCBI chr15:42,273,805...42,333,047
Ensembl chr15:42,273,799...42,333,047
|
|
| G
|
Pip4k2c
|
phosphatidylinositol-5-phosphate 4-kinase type 2 gamma
|
increases response to substance
|
ISO
|
PIP4K2C protein results in increased susceptibility to Arsenic Trioxide
|
CTD |
PMID:22496355 |
|
NCBI chr 7:64,905,322...64,920,380
Ensembl chr 7:64,905,328...64,920,373
|
|
| G
|
Pip4p1
|
phosphatidylinositol-4,5-bisphosphate 4-phosphatase 1
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to PIP4P1 protein]
|
CTD |
PMID:26598702 |
|
NCBI chr15:26,620,399...26,624,369
Ensembl chr15:26,620,401...26,624,246
|
|
| G
|
Pir
|
pirin
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of PIR mRNA
|
CTD |
PMID:15761015 PMID:19417148 |
|
NCBI chr X:33,740,428...33,851,049
Ensembl chr X:33,740,429...33,851,049
|
|
| G
|
Pirt
|
phosphoinositide-interacting regulator of transient receptor potential channels
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of PIRT mRNA
|
CTD |
PMID:35676786 |
|
NCBI chr10:52,112,235...52,127,140
Ensembl chr10:52,111,959...52,131,422
|
|
| G
|
Pitpnc1
|
phosphatidylinositol transfer protein, cytoplasmic 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of PITPNC1 mRNA
|
CTD |
PMID:26705709 |
|
NCBI chr10:92,663,260...92,928,616
Ensembl chr10:92,663,260...92,928,344
|
|
| G
|
Pitpnm2
|
phosphatidylinositol transfer protein, membrane-associated 2
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of PITPNM2 mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr12:38,008,399...38,140,046
Ensembl chr12:38,066,006...38,140,046
|
|
| G
|
Pkd2l1
|
polycystin 2 like 1, transient receptor potential cation channel
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of PKD2L1 mRNA
|
CTD |
PMID:19128835 |
|
NCBI chr 1:252,982,096...253,019,235
Ensembl chr 1:252,982,096...253,023,359
|
|
| G
|
Pkib
|
cAMP-dependent protein kinase inhibitor beta
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of PKIB mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr20:37,511,564...37,608,607
Ensembl chr20:37,512,822...37,608,401
|
|
| G
|
Pklr
|
pyruvate kinase L/R
|
multiple interactions decreases expression
|
ISO
|
Taurine inhibits the reaction [Arsenic Trioxide results in decreased expression of PKLR mRNA]
|
CTD |
PMID:30362509 |
|
NCBI chr 2:176,840,779...176,849,637
Ensembl chr 2:176,840,764...176,849,644
|
|
| G
|
Pkm
|
pyruvate kinase M1/2
|
multiple interactions increases expression decreases expression
|
ISO
|
[Ascorbic Acid co-treated with Arsenic Trioxide] results in decreased expression of PKM protein; [Tretinoin co-treated with Arsenic Trioxide] results in increased expression of PKM mRNA; Arsenic Trioxide promotes the reaction [Ascorbic Acid results in decreased expression of PKM mRNA]; Arsenic Trioxide promotes the reaction [Ascorbic Acid results in decreased expression of PKM protein]; Ascorbic Acid promotes the reaction [Arsenic Trioxide results in decreased expression of PKM mRNA]; Ascorbic Acid promotes the reaction [Arsenic Trioxide results in decreased expression of PKM protein]; MEG3 protein affects the reaction [Arsenic Trioxide results in decreased expression of PKM mRNA]; MEG3 protein affects the reaction [Arsenic Trioxide results in decreased expression of PKM protein]; PKM protein inhibits the reaction [Arsenic Trioxide results in decreased expression of CDH2 mRNA]; PKM protein inhibits the reaction [Arsenic Trioxide results in decreased expression of CDH2 protein]; PKM protein inhibits the reaction [Arsenic Trioxide results in decreased expression of VIM mRNA]; PKM protein inhibits the reaction [Arsenic Trioxide results in decreased expression of VIM protein]; PKM protein inhibits the reaction [Arsenic Trioxide results in increased expression of CDH1 mRNA]; PKM protein inhibits the reaction [Arsenic Trioxide results in increased expression of CDH1 protein]; PKM protein inhibits the reaction [Arsenic Trioxide results in increased expression of MEG3 mRNA] Arsenic Trioxide results in increased expression of PKM protein Arsenic Trioxide results in decreased expression of PKM mRNA; Arsenic Trioxide results in decreased expression of PKM protein
|
CTD |
PMID:15894607 PMID:25419056 PMID:31003765 PMID:38160894 |
|
NCBI chr 8:68,949,731...68,975,394
Ensembl chr 8:68,948,815...68,975,396
|
|
| G
|
Pkmyt1
|
protein kinase, membrane associated tyrosine/threonine 1
|
increases expression decreases expression
|
ISO
|
Arsenic Trioxide results in increased expression of PKMYT1 mRNA Arsenic Trioxide results in decreased expression of PKMYT1 mRNA
|
CTD |
PMID:20458559 PMID:20862710 |
|
NCBI chr10:13,252,805...13,263,584
Ensembl chr10:13,252,816...13,264,263
|
|
| G
|
Pknox1
|
PBX/knotted 1 homeobox 1
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of PKNOX1 mRNA
|
CTD |
PMID:15761015 |
|
NCBI chr20:9,664,120...9,706,328
Ensembl chr20:9,664,312...9,706,349
|
|
| G
|
Pknox2
|
PBX/knotted 1 homeobox 2
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to PKNOX2 protein]
|
CTD |
PMID:26598702 |
|
NCBI chr 8:44,789,464...45,051,933
Ensembl chr 8:44,789,467...44,979,754
|
|
| G
|
Pkp1
|
plakophilin 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of PKP1 protein
|
CTD |
PMID:25419056 |
|
NCBI chr13:49,861,340...49,909,162
Ensembl chr13:49,861,340...49,909,162
|
|
| G
|
Pkp3
|
plakophilin 3
|
decreases response to substance
|
ISO
|
PKP3 protein results in decreased susceptibility to Arsenic Trioxide
|
CTD |
PMID:20707922 |
|
NCBI chr 1:205,617,511...205,628,441
Ensembl chr 1:205,617,511...205,628,440
|
|
| G
|
Pla2g1b
|
phospholipase A2 group IB
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of PLA2G1B mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr12:46,802,932...46,814,511
Ensembl chr12:46,802,939...46,813,693
|
|
| G
|
Pla2g4a
|
phospholipase A2 group 4A
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of PLA2G4A mRNA
|
CTD |
PMID:24831965 PMID:38758479 |
|
NCBI chr13:64,427,921...64,572,352
Ensembl chr13:64,427,916...64,589,641
|
|
| G
|
Pla2g6
|
phospholipase A2 group VI
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to PLA2G6 protein]
|
CTD |
PMID:26598702 |
|
NCBI chr 7:112,731,803...112,771,978
Ensembl chr 7:112,731,803...112,771,609
|
|
| G
|
Pla2r1
|
phospholipase A2 receptor 1
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to PLA2R1 protein]
|
CTD |
PMID:26598702 |
|
NCBI chr 3:65,292,629...65,422,462
Ensembl chr 3:65,292,629...65,422,335
|
|
| G
|
Plac1
|
placenta enriched 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of PLAC1 mRNA
|
CTD |
PMID:22521957 |
|
NCBI chr X:137,740,896...137,874,688
Ensembl chr X:137,740,890...137,905,210
|
|
| G
|
Plagl2
|
PLAG1 like zinc finger 2
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of PLAGL2 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 3:162,155,554...162,168,748
Ensembl chr 3:162,155,554...162,168,748
|
|
| G
|
Plat
|
plasminogen activator, tissue type
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of PLAT mRNA
|
CTD |
PMID:20458559 PMID:22521957 |
|
NCBI chr16:75,943,061...76,022,037
Ensembl chr16:75,943,064...75,967,696
|
|
| G
|
Plau
|
plasminogen activator, urokinase
|
increases expression multiple interactions decreases expression
|
ISO
|
Arsenic Trioxide results in increased expression of PLAU mRNA [Silybin co-treated with Arsenic Trioxide] results in decreased expression of PLAU mRNA; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in decreased secretion of PLAU protein]; Arsenic Trioxide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of PLAU protein]; Arsenic Trioxide promotes the reaction [Silybin results in decreased expression of PLAU mRNA]; Arsenic Trioxide results in decreased expression of and results in decreased secretion of PLAU protein; GH1 protein promotes the reaction [Arsenic Trioxide results in decreased expression of PLAU mRNA]; Silybin promotes the reaction [Arsenic Trioxide results in decreased expression of PLAU mRNA]
|
CTD |
PMID:15962302 PMID:20458559 PMID:21969006 PMID:23851143 PMID:27039805 PMID:37969188 More...
|
|
NCBI chr15:3,505,485...3,511,987
Ensembl chr15:3,505,487...3,512,030
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| G
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Plaur
|
plasminogen activator, urokinase receptor
|
decreases expression multiple interactions
|
ISO
|
Arsenic Trioxide results in decreased expression of PLAUR mRNA; Arsenic Trioxide results in decreased expression of PLAUR protein GH1 protein promotes the reaction [Arsenic Trioxide results in decreased expression of PLAUR mRNA]
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CTD |
PMID:15761015 PMID:15962302 PMID:19128835 PMID:19642359 PMID:23851143 |
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NCBI chr 1:89,181,363...89,196,308
Ensembl chr 1:89,178,453...89,198,130
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| G
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Plcb1
|
phospholipase C beta 1
|
decreases expression increases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of PLCB1 mRNA Arsenic Trioxide results in increased expression of PLCB1 mRNA
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CTD |
PMID:24831965 PMID:39716349 |
|
NCBI chr 3:142,512,765...143,224,042
Ensembl chr 3:142,513,033...143,225,646
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| G
|
Plcb4
|
phospholipase C, beta 4
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of PLCB4 mRNA; Arsenic Trioxide results in decreased expression of PLCB4 protein
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CTD |
PMID:24831965 |
|
NCBI chr 3:143,405,721...143,775,129
Ensembl chr 3:143,405,950...143,775,113
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|
| G
|
Plcd1
|
phospholipase C, delta 1
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to PLCD1 protein]
|
CTD |
PMID:26598702 |
|
NCBI chr 8:127,672,955...127,695,939
Ensembl chr 8:127,672,980...127,695,939
|
|
| G
|
Plcg2
|
phospholipase C, gamma 2
|
decreases phosphorylation
|
ISO
|
Arsenic Trioxide results in decreased phosphorylation of PLCG2 protein
|
CTD |
PMID:20129490 |
|
NCBI chr19:62,456,196...62,592,684
Ensembl chr19:62,453,259...62,592,684
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|
| G
|
Plcl1
|
phospholipase C-like 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of PLCL1 mRNA
|
CTD |
PMID:24356939 |
|
NCBI chr 9:64,395,976...64,733,171
Ensembl chr 9:64,361,520...64,733,171
|
|
| G
|
Plcxd1
|
phosphatidylinositol-specific phospholipase C, X domain containing 1
|
decreases expression
|
ISO
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Arsenic Trioxide results in decreased expression of PLCXD1 mRNA
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CTD |
PMID:20458559 |
|
NCBI chr12:52,238,450...52,241,884
Ensembl chr12:52,238,623...52,241,865
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|
| G
|
Pld1
|
phospholipase D1
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of PLD1 mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr 2:112,777,820...112,975,857
Ensembl chr 2:112,777,951...112,976,245
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| G
|
Pld3
|
phospholipase D family, member 3
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of PLD3 mRNA
|
CTD |
PMID:22521957 |
|
NCBI chr 1:91,949,465...91,971,834
Ensembl chr 1:91,949,467...91,961,207
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|
| G
|
Pld5
|
phospholipase D family, member 5
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of PLD5 mRNA
|
CTD |
PMID:26705709 |
|
NCBI chr13:90,426,689...90,765,072
Ensembl chr13:90,428,490...90,783,066
|
|
| G
|
Plek2
|
pleckstrin 2
|
decreases response to substance
|
ISO
|
PLEK2 protein results in decreased susceptibility to Arsenic Trioxide
|
CTD |
PMID:20707922 |
|
NCBI chr 6:103,434,156...103,452,457
Ensembl chr 6:103,434,156...103,452,371
|
|
| G
|
Plekha6
|
pleckstrin homology domain containing A6
|
decreases response to substance
|
ISO
|
PLEKHA6 protein results in decreased susceptibility to Arsenic Trioxide
|
CTD |
PMID:20707922 |
|
NCBI chr13:47,166,899...47,307,003
Ensembl chr13:47,167,160...47,307,003
|
|
| G
|
Plekhg1
|
pleckstrin homology and RhoGEF domain containing G1
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of PLEKHG1 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 1:42,612,023...42,841,727
Ensembl chr 1:42,612,122...42,841,719
|
|
| G
|
Plekhg3
|
pleckstrin homology and RhoGEF domain containing G3
|
decreases response to substance
|
ISO
|
PLEKHG3 protein results in decreased susceptibility to Arsenic Trioxide
|
CTD |
PMID:20707922 |
|
NCBI chr 6:100,998,965...101,042,120
Ensembl chr 6:100,994,417...101,042,118
|
|
| G
|
Plekhg6
|
pleckstrin homology and RhoGEF domain containing G6
|
decreases response to substance
|
ISO
|
PLEKHG6 protein results in decreased susceptibility to Arsenic Trioxide
|
CTD |
PMID:20707922 |
|
NCBI chr 4:159,849,987...159,885,730
Ensembl chr 4:159,849,364...159,868,122
|
|
| G
|
Plekhm2
|
pleckstrin homology and RUN domain containing M2
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to PLEKHM2 protein]
|
CTD |
PMID:26598702 |
|
NCBI chr 5:159,222,620...159,261,666
Ensembl chr 5:159,223,300...159,261,642
|
|
| G
|
Plekhm3
|
pleckstrin homology domain containing M3
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of PLEKHM3 mRNA
|
CTD |
PMID:35676786 |
|
NCBI chr 9:73,659,998...73,819,079
Ensembl chr 9:73,664,817...73,799,503
|
|
| G
|
Plekho1
|
pleckstrin homology domain containing O1
|
decreases expression increases response to substance
|
ISO
|
Arsenic Trioxide results in decreased expression of PLEKHO1 mRNA PLEKHO1 protein results in increased susceptibility to Arsenic Trioxide
|
CTD |
PMID:15761015 PMID:20707922 |
|
NCBI chr 2:186,233,435...186,242,114
Ensembl chr 2:186,233,452...186,241,354
|
|
| G
|
Plg
|
plasminogen
|
decreases activity
|
ISO
|
Arsenic Trioxide results in decreased activity of PLG protein
|
CTD |
PMID:19781379 |
|
NCBI chr 1:50,872,927...50,915,406
Ensembl chr 1:50,872,926...50,917,320
|
|
| G
|
Plin2
|
perilipin 2
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of PLIN2 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 5:106,202,634...106,258,748
Ensembl chr 5:106,202,634...106,258,878
|
|
| G
|
Plk1
|
polo-like kinase 1
|
multiple interactions increases phosphorylation
|
ISO
|
4-(4-(N-benzoylamino)anilino)-6-methoxy-7-(3-(1-morpholino)propoxy)quinazoline inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of PLK1 protein]; BI 2536 inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of PLK1 protein]; RO3280 inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of PLK1 protein]
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CTD |
PMID:31597699 |
|
NCBI chr 1:186,147,658...186,157,637
Ensembl chr 1:186,147,658...186,157,637
|
|
| G
|
Plk3
|
polo-like kinase 3
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of PLK3 mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr 5:135,843,725...135,848,900
Ensembl chr 5:135,843,725...135,848,900
|
|
| G
|
Plk4
|
polo-like kinase 4
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of PLK4 mRNA
|
CTD |
PMID:26705709 |
|
NCBI chr 2:125,730,480...125,748,894
Ensembl chr 2:125,730,460...125,748,892
|
|
| G
|
Pllp
|
plasmolipin
|
decreases response to substance
|
ISO
|
PLLP protein results in decreased susceptibility to Arsenic Trioxide
|
CTD |
PMID:20707922 |
|
NCBI chr19:10,321,080...10,341,869
Ensembl chr19:10,321,080...10,342,226
|
|
| G
|
Plp1
|
proteolipid protein 1
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of PLP1 mRNA
|
CTD |
PMID:26705709 |
|
NCBI chr X:104,933,921...104,993,317
Ensembl chr X:104,975,780...104,993,314
|
|
| G
|
Plpp1
|
phospholipid phosphatase 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of PLPP1 mRNA
|
CTD |
PMID:22521957 |
|
NCBI chr 2:46,172,202...46,233,632
Ensembl chr 2:46,172,197...46,234,676
|
|
| G
|
Plpp2
|
phospholipid phosphatase 2
|
decreases response to substance
|
ISO
|
PLPP2 protein results in decreased susceptibility to Arsenic Trioxide
|
CTD |
PMID:20707922 |
|
NCBI chr 7:10,826,534...10,834,628
Ensembl chr 7:10,826,549...10,834,627
|
|
| G
|
Plpp3
|
phospholipid phosphatase 3
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of PLPP3 mRNA
|
CTD |
PMID:19128835 |
|
NCBI chr 5:125,156,000...125,231,119
Ensembl chr 5:125,155,945...125,235,667
|
|
| G
|
Plppr5
|
phospholipid phosphatase related 5
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of PLPPR5 mRNA
|
CTD |
PMID:26705709 |
|
NCBI chr 2:208,143,058...208,422,836
Ensembl chr 2:208,142,871...208,439,051
|
|
| G
|
Plscr1
|
phospholipid scramblase 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of PLSCR1 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 8:101,662,512...101,684,474
Ensembl chr 8:101,664,056...101,684,614
|
|
| G
|
Pltp
|
phospholipid transfer protein
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of PLTP mRNA
|
CTD |
PMID:19128835 |
|
NCBI chr 3:173,994,162...174,011,982
Ensembl chr 3:173,994,162...174,012,505
|
|
| G
|
Plxna3
|
plexin A3
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of PLXNA3 mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr X:157,266,986...157,282,896
Ensembl chr X:157,267,107...157,282,891
|
|
| G
|
Plxnb1
|
plexin B1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of PLXNB1 mRNA
|
CTD |
PMID:35676786 |
|
NCBI chr 8:118,621,961...118,647,491
Ensembl chr 8:118,623,040...118,647,489
|
|
| G
|
Plxnb2
|
plexin B2
|
decreases response to substance
|
ISO
|
PLXNB2 protein results in decreased susceptibility to Arsenic Trioxide
|
CTD |
PMID:20707922 |
|
NCBI chr 7:122,111,917...122,138,201
Ensembl chr 7:122,111,917...122,127,746
|
|
| G
|
Plxnc1
|
plexin C1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of PLXNC1 mRNA
|
CTD |
PMID:15761015 |
|
NCBI chr 7:31,276,978...31,430,823
Ensembl chr 7:31,276,978...31,431,092
|
|
| G
|
Pmaip1
|
phorbol-12-myristate-13-acetate-induced protein 1
|
increases expression decreases expression multiple interactions
|
ISO
|
Arsenic Trioxide results in increased expression of PMAIP1 mRNA Arsenic Trioxide results in decreased expression of PMAIP1 mRNA [Arsenic Trioxide co-treated with Bortezomib] results in decreased expression of PMAIP1 mRNA; [Bortezomib co-treated with Arsenic Trioxide] results in increased expression of PMAIP1 protein; [sanguinarine co-treated with Arsenic Trioxide] results in increased expression of PMAIP1 mRNA; GH1 protein promotes the reaction [Arsenic Trioxide results in increased expression of PMAIP1 mRNA]; PMAIP1 protein promotes the reaction [[Bortezomib co-treated with Arsenic Trioxide] results in increased activity of CASP3 protein]; PMAIP1 protein promotes the reaction [Arsenic Trioxide results in increased activity of CASP3 protein]
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CTD |
PMID:19417148 PMID:20458559 PMID:21518486 PMID:23851143 PMID:24345465 PMID:25258189 PMID:25913414 More...
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|
NCBI chr18:62,255,970...62,262,384
Ensembl chr18:62,255,598...62,262,382
|
|
| G
|
Pml
|
PML nuclear body scaffold
|
affects metabolic processing increases expression decreases response to substance increases ubiquitination increases response to substance affects localization multiple interactions affects binding increases sumoylation decreases expression affects response to substance increases degradation
|
ISO
|
Arsenic Trioxide affects the metabolism of PML protein Arsenic Trioxide results in increased expression of PML mRNA PML gene mutant form results in decreased susceptibility to Arsenic Trioxide; PML protein mutant form results in decreased susceptibility to Arsenic Trioxide; PML protein results in decreased susceptibility to Arsenic Trioxide Arsenic Trioxide results in increased ubiquitination of PML protein; Arsenic Trioxide results in increased ubiquitination of PML protein alternative form PML mutant form results in increased susceptibility to Arsenic Trioxide Arsenic Trioxide affects the localization of PML protein Arsenic Trioxide inhibits the reaction [Bleomycin results in increased expression of PML protein]; Arsenic Trioxide results in increased sumoylation of and results in increased localization of and results in increased degradation of [PML protein mutant form binds to PML protein mutant form] Arsenic Trioxide binds to PML protein; Arsenic Trioxide binds to PML protein modified form Arsenic Trioxide results in increased expression of PML protein modified form Arsenic Trioxide results in increased sumoylation of PML protein; Arsenic Trioxide results in increased sumoylation of PML protein alternative form Arsenic Trioxide results in decreased expression of PML mRNA mutant form; Arsenic Trioxide results in decreased expression of PML protein; Arsenic Trioxide results in decreased expression of PML protein mutant form PML protein affects the susceptibility to Arsenic Trioxide [[Arsenic Trioxide results in increased sumoylation of PML protein alternative form] promotes the reaction [PML protein alternative form binds to RNF4 protein]] which results in increased degradation of PML protein alternative form; [[Arsenic Trioxide results in increased sumoylation of PML protein] promotes the reaction [PML protein binds to RNF4 protein]] which results in increased degradation of PML protein; [Arsenic Trioxide affects the reaction [SUMO2 protein binds to PML protein]] promotes the reaction [SUMO1 protein binds to PML protein]; [Arsenic Trioxide affects the reaction [SUMO2 protein binds to PML protein]] which results in increased ubiquitination of PML protein; [Arsenic Trioxide co-treated with PML protein] results in decreased expression of BCL2; [Arsenic Trioxide co-treated with PML protein] results in increased expression of TP53; [Arsenic Trioxide promotes the reaction [SUMO1 protein binds to PML protein]] which results in increased ubiquitination of PML protein; [Arsenic Trioxide promotes the reaction [UBE2I protein binds to PML protein]] which results in increased sumoylation of PML protein; [Arsenic Trioxide results in increased sumoylation of PML protein alternative form] promotes the reaction [PML protein alternative form binds to RNF4 protein]; [Arsenic Trioxide results in increased sumoylation of PML protein] promotes the reaction [PML protein binds to RNF4 protein]; [monomethylarsonous acid co-treated with dimethylarsinous acid co-treated with Arsenic Trioxide] results in increased degradation of PML protein; [Tretinoin co-treated with Arsenic Trioxide] results in decreased expression of PML mRNA alternative form; [Tretinoin co-treated with Arsenic Trioxide] results in increased degradation of PML protein mutant form; [Vorinostat co-treated with Arsenic Trioxide] results in decreased expression of PML protein mutant form; ALDH3A1 protein inhibits the reaction [PML mutant form results in increased susceptibility to Arsenic Trioxide]; Arsenic Trioxide affects the localization of and results in decreased expression of PML protein; Arsenic Trioxide affects the reaction [PML protein modified form binds to DAXX protein]; Arsenic Trioxide affects the reaction [SUMO2 protein binds to PML protein]; Arsenic Trioxide affects the sumoylation of and results in increased ubiquitination of and results in increased cleavage of PML protein; Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to PML protein]; Arsenic Trioxide inhibits the reaction [p-aminophenylarsine oxide binds to PML protein]; Arsenic Trioxide promotes the reaction [PML protein binds to PML protein]; Arsenic Trioxide promotes the reaction [puerarin results in decreased expression of PML mRNA alternative form]; Arsenic Trioxide promotes the reaction [RNF4 protein binds to and results in increased degradation of PML protein modified form]; Arsenic Trioxide promotes the reaction [RNF4 protein results in increased degradation of PML protein alternative form]; Arsenic Trioxide promotes the reaction [RNF4 protein results in increased degradation of PML protein]; Arsenic Trioxide promotes the reaction [SUMO1 protein binds to PML protein]; Arsenic Trioxide promotes the reaction [SUMO2 protein binds to PML protein]; Arsenic Trioxide promotes the reaction [tetraarsenic tetrasulfide results in increased degradation of [PML protein mutant form binds to RARA protein mutant form]]; Arsenic Trioxide promotes the reaction [UBE2I protein binds to PML protein]; Arsenic Trioxide results in increased degradation of [PML protein mutant form binds to RARA protein mutant form]; Arsenic Trioxide results in increased expression of and results in increased sumoylation of PML protein; Arsenic Trioxide results in increased localization of [CASP8AP2 protein co-treated with PML protein]; Arsenic Trioxide results in increased localization of and results in increased degradation of PML protein; Arsenic Trioxide results in increased phosphorylation of and results in increased sumoylation of PML protein; Arsenic Trioxide results in increased sumoylation of and results in increased localization of PML protein; Arsenic Trioxide results in increased ubiquitination of and results in increased degradation of PML protein; cobaltous chloride promotes the reaction [Arsenic Trioxide results in increased degradation of PML protein mutant form]; Cycloheximide inhibits the reaction [Arsenic Trioxide results in increased degradation of PML protein]; Fenofibrate promotes the reaction [Arsenic Trioxide results in decreased expression of PML protein mutant form]; PIAS1 protein promotes the reaction [Arsenic Trioxide results in increased degradation of PML protein]; PML gene mutant form results in decreased susceptibility to [Arsenic Trioxide co-treated with Tretinoin]; PML protein affects the reaction [Arsenic Trioxide results in increased expression of ACTA2 protein]; PML protein affects the reaction [Arsenic Trioxide results in increased expression of SUMO1 protein]; PML protein affects the reaction [Arsenic Trioxide results in increased expression of TGFB1 protein]; RNF4 protein promotes the reaction [Arsenic Trioxide results in increased degradation of PML protein]; RNF4 protein promotes the reaction [Arsenic Trioxide results in increased ubiquitination of PML protein]; SENP1 protein promotes the reaction [Arsenic Trioxide affects the reaction [SUMO2 protein binds to PML protein]]; SENP1 protein promotes the reaction [Arsenic Trioxide affects the sumoylation of and results in increased ubiquitination of PML protein]; SENP1 protein promotes the reaction [Arsenic Trioxide promotes the reaction [SUMO1 protein binds to PML protein]]; SUMO1 protein promotes the reaction [Arsenic Trioxide results in increased ubiquitination of PML protein]; SUMO2 protein mutant form inhibits the reaction [Arsenic Trioxide affects the reaction [SUMO2 protein binds to PML protein]]; SUMO2 protein mutant form inhibits the reaction [Arsenic Trioxide promotes the reaction [SUMO1 protein binds to PML protein]]; SUMO2 protein mutant form inhibits the reaction [Arsenic Trioxide results in increased ubiquitination of PML protein]; tetraarsenic tetrasulfide promotes the reaction [Arsenic Trioxide results in increased degradation of [PML protein mutant form binds to RARA protein mutant form]]; UBE2I protein affects the reaction [Arsenic Trioxide results in increased expression of and results in increased sumoylation of PML protein] Arsenic Trioxide results in increased degradation of PML protein; Arsenic Trioxide results in increased degradation of PML protein mutant form
|
CTD |
PMID:8704214 PMID:9450572 PMID:9716575 PMID:9834237 PMID:11721366 PMID:15093545 PMID:15622748 PMID:15748426 PMID:16330433 PMID:16891316 PMID:17081986 PMID:17217047 PMID:18469801 PMID:19225113 PMID:20377131 PMID:20378816 PMID:20416161 PMID:20609355 PMID:20943951 PMID:21217775 PMID:21613260 PMID:21921037 PMID:22362285 PMID:22406621 PMID:23028697 PMID:23430110 PMID:23440206 PMID:23469683 PMID:23673342 PMID:23734343 PMID:24762191 PMID:26060329 PMID:26110921 PMID:26118777 PMID:26285909 PMID:26598702 PMID:26728337 PMID:27189198 PMID:27770503 PMID:29266867 PMID:29774349 PMID:32240679 PMID:32929351 More...
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|
NCBI chr 8:67,523,164...67,557,801
Ensembl chr 8:67,523,164...67,576,083
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| G
|
Pmm1
|
phosphomannomutase 1
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of PMM1 mRNA
|
CTD |
PMID:35676786 |
|
NCBI chr 7:115,346,767...115,357,137
Ensembl chr 7:115,346,771...115,357,024
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|
| G
|
Pmm2
|
phosphomannomutase 2
|
increases expression multiple interactions
|
ISO
|
Arsenic Trioxide results in increased expression of PMM2 mRNA Metformin inhibits the reaction [Arsenic Trioxide results in increased expression of PMM2 mRNA]
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CTD |
PMID:29095437 PMID:39716349 |
|
NCBI chr10:7,468,371...7,489,574
Ensembl chr10:7,468,372...7,489,554
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|
| G
|
Pmpcb
|
peptidase, mitochondrial processing subunit beta
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of PMPCB protein
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CTD |
PMID:25419056 |
|
NCBI chr 4:14,189,807...14,202,584
Ensembl chr 4:14,165,844...14,202,615
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|
| G
|
Pms2
|
PMS1 homolog 2, mismatch repair system component
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of PMS2 mRNA
|
CTD |
PMID:22521957 |
|
NCBI chr12:15,790,478...15,814,790
Ensembl chr12:15,790,478...15,815,248
|
|
| G
|
Pnma1
|
PNMA family member 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of PNMA1 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 6:109,513,382...109,515,167
Ensembl chr 6:109,507,773...109,515,451
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|
| G
|
Pnp
|
purine nucleoside phosphorylase
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of PNP mRNA; Arsenic Trioxide results in decreased expression of PNP protein
|
CTD |
PMID:19128835 PMID:25419056 |
|
NCBI chr15:26,644,147...26,651,808
Ensembl chr15:26,643,858...26,678,162
|
|
| G
|
Pnpla6
|
patatin-like phospholipase domain containing 6
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of PNPLA6 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr12:6,372,284...6,401,632
Ensembl chr12:6,372,293...6,401,631
|
|
| G
|
Pnpo
|
pyridoxamine 5'-phosphate oxidase
|
decreases response to substance
|
ISO
|
PNPO protein results in decreased susceptibility to Arsenic Trioxide
|
CTD |
PMID:20707922 |
|
NCBI chr10:82,421,027...82,427,288
Ensembl chr10:82,421,027...82,427,288
|
|
| G
|
Pnrc1
|
proline-rich nuclear receptor coactivator 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of PNRC1 mRNA
|
CTD |
PMID:20458559 PMID:24356939 |
|
NCBI chr 5:52,443,400...52,489,303
Ensembl chr 5:52,443,400...52,446,491
|
|
| G
|
Poc1b
|
POC1 centriolar protein B
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of POC1B mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr 7:35,810,761...35,912,571
Ensembl chr 7:35,810,820...35,912,571
|
|
| G
|
Podxl
|
podocalyxin-like
|
affects expression decreases expression
|
ISO
|
Arsenic Trioxide affects the expression of PODXL mRNA Arsenic Trioxide results in decreased expression of PODXL mRNA
|
CTD |
PMID:19128835 PMID:26705709 PMID:28786057 |
|
NCBI chr 4:61,102,434...61,149,131
Ensembl chr 4:61,102,419...61,149,789
|
|
| G
|
Pofut2
|
protein O-fucosyltransferase 2
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of POFUT2 mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr20:11,366,636...11,378,252
Ensembl chr20:11,366,636...11,377,824
|
|
| G
|
Pold1
|
DNA polymerase delta 1, catalytic subunit
|
increases expression multiple interactions
|
ISO
|
Arsenic Trioxide results in increased expression of POLD1 mRNA Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to POLD1 protein]
|
CTD |
PMID:26598702 PMID:29633893 |
|
NCBI chr 1:104,161,984...104,178,074
Ensembl chr 1:104,162,016...104,172,982
|
|
| G
|
Pold3
|
DNA polymerase delta 3, accessory subunit
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of POLD3 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 1:163,830,217...163,870,015
Ensembl chr 1:163,830,437...163,869,202
|
|
| G
|
Pold4
|
DNA polymerase delta 4, accessory subunit
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of POLD4 mRNA
|
CTD |
PMID:22521957 |
|
NCBI chr 1:210,956,110...210,957,863
Ensembl chr 1:210,956,099...210,957,860
|
|
| G
|
Poldip2
|
DNA polymerase delta interacting protein 2
|
increases expression decreases response to substance
|
ISO
|
Arsenic Trioxide results in increased expression of POLDIP2 mRNA POLDIP2 protein results in decreased susceptibility to Arsenic Trioxide
|
CTD |
PMID:20458559 PMID:20707922 |
|
NCBI chr10:63,905,287...63,915,655
Ensembl chr10:63,904,691...63,915,655
|
|
| G
|
Pole
|
DNA polymerase epsilon, catalytic subunit
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of POLE mRNA
|
CTD |
PMID:34413873 |
|
NCBI chr12:52,005,155...52,053,761
Ensembl chr12:52,005,155...52,053,662
|
|
| G
|
Pole2
|
DNA polymerase epsilon 2, accessory subunit
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of POLE2 mRNA
|
CTD |
PMID:34413873 |
|
NCBI chr 6:93,410,713...93,448,782
Ensembl chr 6:93,410,758...93,435,361
|
|
| G
|
Pole4
|
DNA polymerase epsilon 4, accessory subunit
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of POLE4 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 4:116,723,040...116,728,873
Ensembl chr 4:116,716,719...116,728,851
|
|
| G
|
Polg2
|
DNA polymerase gamma 2, accessory subunit
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of POLG2 mRNA
|
CTD |
PMID:27829220 |
|
NCBI chr10:92,212,303...92,222,849
Ensembl chr10:92,212,304...92,222,726
|
|
| G
|
Polr2a
|
RNA polymerase II subunit A
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of POLR2A mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr10:54,951,162...54,977,179
Ensembl chr10:54,951,162...54,977,179
|
|
| G
|
Polr2c
|
RNA polymerase II subunit C
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of POLR2C mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr19:10,164,148...10,170,930
Ensembl chr19:10,164,145...10,170,971
|
|
| G
|
Polr2e
|
RNA polymerase II, I and III subunit E
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of POLR2E protein
|
CTD |
PMID:25419056 |
|
NCBI chr 7:10,317,332...10,321,280
Ensembl chr 7:10,317,389...10,321,276
|
|
| G
|
Polr2f
|
RNA polymerase II, I and III subunit F
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of POLR2F protein
|
CTD |
PMID:30093655 |
|
NCBI chr 7:112,592,977...112,604,681
Ensembl chr 7:112,593,027...112,604,666
|
|
| G
|
Pomt1
|
protein-O-mannosyltransferase 1
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of POMT1 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 3:35,918,370...35,936,330
Ensembl chr 3:35,918,188...35,936,364
|
|
| G
|
Popdc1
|
popeye domain cAMP effector 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of POPDC1 mRNA
|
CTD |
PMID:27829220 |
|
NCBI chr20:50,401,611...50,442,653
Ensembl chr20:50,401,733...50,442,645
|
|
| G
|
Popdc2
|
popeye domain cAMP effector 2
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of POPDC2 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr11:75,850,068...75,897,094
Ensembl chr11:75,880,274...75,896,269
|
|
| G
|
Postn
|
periostin
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of POSTN mRNA
|
CTD |
PMID:26705709 |
|
NCBI chr 2:140,677,774...140,709,304
Ensembl chr 2:140,677,754...140,709,300
|
|
| G
|
Poteh
|
POTE ankyrin domain family member H
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of ANKRD18A mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr15:19,559,450...19,654,345
|
|
| G
|
Pou2f1
|
POU class 2 homeobox 1
|
increases expression decreases expression
|
ISO
|
Arsenic Trioxide results in increased expression of POU2F1 mRNA Arsenic Trioxide results in decreased expression of POU2F1 mRNA
|
CTD |
PMID:20458559 PMID:39716349 |
|
NCBI chr13:80,653,602...80,796,279
Ensembl chr13:80,663,714...80,796,356
|
|
| G
|
Pou4f1
|
POU class 4 homeobox 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of POU4F1 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr15:87,668,328...87,674,643
Ensembl chr15:87,668,328...87,674,643
|
|
| G
|
Pou5f1
|
POU class 5 homeobox 1
|
decreases expression increases expression multiple interactions
|
ISO
|
Arsenic Trioxide results in decreased expression of POU5F1 mRNA; Arsenic Trioxide results in decreased expression of POU5F1 protein Arsenic Trioxide results in increased expression of POU5F1 mRNA; Arsenic Trioxide results in increased expression of POU5F1 protein [Arsenic Trioxide co-treated with FN1 protein] results in decreased expression of POU5F1 mRNA Arsenic Trioxide promotes the reaction [MSI1 protein results in increased expression of POU5F1 protein]; EIF2AK2 protein affects the reaction [Arsenic Trioxide promotes the reaction [MSI1 protein results in increased expression of POU5F1 protein]]; EIF2AK2 protein affects the reaction [Arsenic Trioxide results in increased expression of POU5F1 protein]; EIF2S1 protein affects the reaction [Arsenic Trioxide promotes the reaction [MSI1 protein results in increased expression of POU5F1 protein]]; ICG 001 affects the reaction [RORB protein affects the reaction [Arsenic Trioxide results in decreased expression of POU5F1 protein]]; MSI1 protein affects the reaction [Arsenic Trioxide results in increased expression of POU5F1 protein]; PTGS2 protein affects the reaction [Arsenic Trioxide results in increased expression of POU5F1 protein]; RORB protein affects the reaction [Arsenic Trioxide results in decreased expression of POU5F1 protein]; SOX2 protein affects the reaction [Arsenic Trioxide results in increased expression of POU5F1 protein]; SOX2 protein affects the reaction [PTGS2 protein affects the reaction [Arsenic Trioxide results in increased expression of POU5F1 protein]]
|
CTD |
PMID:22641096 PMID:29396848 PMID:29486283 PMID:29767511 PMID:33634982 PMID:38797699 More...
|
|
NCBI chr20:3,227,836...3,232,598
Ensembl chr20:3,227,837...3,232,598
|
|
| G
|
Ppara
|
peroxisome proliferator activated receptor alpha
|
multiple interactions increases expression decreases expression
|
ISO
|
3-methyladenine inhibits the reaction [Arsenic Trioxide results in increased expression of PPARA protein]; MK-886 inhibits the reaction [Arsenic Trioxide results in increased expression of PPARA protein]; Taurine inhibits the reaction [Arsenic Trioxide results in increased expression of PPARA protein] Arsenic Trioxide results in decreased expression of PPARA mRNA; Arsenic Trioxide results in decreased expression of PPARA protein
|
CTD |
PMID:21257625 PMID:22521957 PMID:30237538 PMID:30677399 |
|
NCBI chr 7:118,712,261...118,780,723
Ensembl chr 7:118,712,412...118,780,714
|
|
| G
|
Pparg
|
peroxisome proliferator-activated receptor gamma
|
decreases response to substance decreases expression increases expression multiple interactions
|
ISO EXP
|
PPARG protein results in decreased susceptibility to Arsenic Trioxide Arsenic Trioxide results in decreased expression of PPARG protein Arsenic Trioxide results in increased expression of PPARG mRNA; Arsenic Trioxide results in increased expression of PPARG protein [Rosiglitazone binds to and results in increased activity of PPARG protein] which results in increased susceptibility to Arsenic Trioxide; [Tretinoin co-treated with Arsenic Trioxide] results in increased expression of PPARG protein; [Troglitazone binds to and results in increased activity of PPARG protein] which results in increased susceptibility to Arsenic Trioxide; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased expression of and results in decreased phosphorylation of PPARG protein]; Arsenic Trioxide results in increased expression of and results in decreased activity of PPARG protein; Arsenic Trioxide results in increased expression of and results in decreased phosphorylation of PPARG protein; KEAP1 protein inhibits the reaction [Arsenic Trioxide results in increased expression of PPARG mRNA]; KEAP1 protein inhibits the reaction [Arsenic Trioxide results in increased expression of PPARG protein]; NFE2L2 protein promotes the reaction [Arsenic Trioxide results in increased expression of PPARG mRNA]; Pioglitazone inhibits the reaction [Arsenic Trioxide results in increased expression of and results in decreased phosphorylation of PPARG protein]; Rosiglitazone inhibits the reaction [Arsenic Trioxide results in decreased expression of PPARG protein]; Taurine inhibits the reaction [Arsenic Trioxide results in decreased expression of PPARG protein] Arsenic Trioxide inhibits the reaction [AKT1 protein binds to PPARG protein]; Arsenic Trioxide inhibits the reaction [RXRA protein binds to PPARG protein]; Taurine inhibits the reaction [Arsenic Trioxide results in decreased expression of PPARG protein] Arsenic Trioxide results in decreased expression of PPARG mRNA Nicorandil inhibits the reaction [Arsenic Trioxide results in increased expression of PPARG protein]
|
CTD |
PMID:15916724 PMID:20707922 PMID:22684020 PMID:30362509 PMID:31258454 PMID:32929351 PMID:34108876 PMID:38741475 PMID:38781725 More...
|
|
NCBI chr 4:150,095,743...150,221,104
Ensembl chr 4:150,095,787...150,221,104
|
|
| G
|
Ppargc1a
|
PPARG coactivator 1 alpha
|
increases expression multiple interactions decreases expression
|
ISO EXP
|
Arsenic Trioxide results in increased expression of PPARGC1A mRNA Nicorandil inhibits the reaction [Arsenic Trioxide results in increased expression of PPARGC1A mRNA]; salvianolic acid A inhibits the reaction [Arsenic Trioxide results in decreased expression of PPARGC1A protein] salvianolic acid A inhibits the reaction [Arsenic Trioxide results in decreased expression of PPARGC1A protein]; Taurine inhibits the reaction [Arsenic Trioxide results in increased expression of PPARGC1A mRNA] Acetylcysteine inhibits the reaction [Arsenic Trioxide results in decreased expression of PPARGC1A protein]
|
CTD |
PMID:20458559 PMID:29867492 PMID:30362509 PMID:38741475 PMID:38781725 |
|
NCBI chr14:63,073,505...63,729,215
Ensembl chr14:63,273,189...63,729,213
|
|
| G
|
Ppat
|
phosphoribosyl pyrophosphate amidotransferase
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of PPAT mRNA
|
CTD |
PMID:22521957 |
|
NCBI chr14:31,570,010...31,604,410
Ensembl chr14:31,551,388...31,604,405
|
|
| G
|
Ppbp
|
pro-platelet basic protein
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of PPBP mRNA
|
CTD |
PMID:19128835 |
|
NCBI chr14:17,586,495...17,587,299
Ensembl chr14:17,586,495...17,587,299
|
|
| G
|
Ppfia4
|
PTPRF interacting protein alpha 4
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of PPFIA4 mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr13:48,305,844...48,354,329
Ensembl chr13:48,305,848...48,354,279
|
|
| G
|
Ppia
|
peptidylprolyl isomerase A
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of PPIA mRNA
|
CTD |
PMID:20458559 PMID:22521957 |
|
NCBI chr14:85,491,223...85,496,884
Ensembl chr14:85,492,484...85,497,115
|
|
| G
|
Ppif
|
peptidylprolyl isomerase F
|
increases oxidation
|
ISO
|
Arsenic Trioxide results in increased oxidation of PPIF protein
|
CTD |
PMID:26975474 |
|
NCBI chr16:1,264,001...1,270,722
Ensembl chr16:1,263,541...1,316,954
|
|
| G
|
Ppig
|
peptidylprolyl isomerase G
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of PPIG mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 3:74,891,846...74,923,010
Ensembl chr 3:74,891,846...74,920,750
|
|
| G
|
Ppih
|
peptidylprolyl isomerase H
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of PPIH mRNA
|
CTD |
PMID:17547211 |
|
NCBI chr 5:138,191,624...138,209,625
Ensembl chr 5:138,191,624...138,209,580
|
|
| G
|
Ppil1
|
peptidylprolyl isomerase like 1
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of PPIL1 mRNA
|
CTD |
PMID:35676786 |
|
NCBI chr20:7,303,919...7,323,962
Ensembl chr20:7,303,922...7,318,781
|
|
| G
|
Ppil3
|
peptidylprolyl isomerase like 3
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to PPIL3 protein]
|
CTD |
PMID:26598702 |
|
NCBI chr 9:67,460,594...67,474,325
Ensembl chr 9:67,460,595...67,474,251
|
|
| G
|
Ppm1a
|
protein phosphatase, Mg2+/Mn2+ dependent, 1A
|
decreases expression multiple interactions
|
ISO
|
Arsenic Trioxide results in decreased expression of PPM1A mRNA Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to PPM1A protein]
|
CTD |
PMID:20458559 PMID:26598702 |
|
NCBI chr 6:97,174,955...97,216,585
Ensembl chr 6:97,174,916...97,216,574
|
|
| G
|
Ppm1d
|
protein phosphatase, Mg2+/Mn2+ dependent, 1D
|
multiple interactions affects activity decreases expression increases expression
|
ISO
|
Metformin inhibits the reaction [Arsenic Trioxide results in increased expression of PPM1D mRNA] MIR29A protein affects the reaction [Arsenic Trioxide results in decreased expression of PPM1D protein]; PPM1D mutant form promotes the reaction [Arsenic Trioxide results in increased phosphorylation of and results in increased activity of CHEK2 protein]; PPM1D mutant form promotes the reaction [Arsenic Trioxide results in increased phosphorylation of and results in increased activity of MAPK14 protein] Arsenic Trioxide affects the activity of PPM1D
|
CTD |
PMID:18482988 PMID:21175813 PMID:29095437 |
|
NCBI chr10:70,670,026...70,706,030
Ensembl chr10:70,670,020...70,706,256
|
|
| G
|
Ppm1k
|
protein phosphatase, Mg2+/Mn2+ dependent, 1K
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of PPM1K mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr 4:88,942,226...88,969,139
Ensembl chr 4:88,942,386...88,969,136
|
|
| G
|
Ppme1
|
protein phosphatase methylesterase 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of PPME1 mRNA; Arsenic Trioxide results in increased expression of PPME1 protein
|
CTD |
PMID:20458559 PMID:25419056 |
|
NCBI chr 1:164,080,242...164,127,261
Ensembl chr 1:164,080,242...164,127,220
|
|
| G
|
Ppp1ca
|
protein phosphatase 1 catalytic subunit alpha
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of PPP1CA protein
|
CTD |
PMID:25419056 |
|
NCBI chr 1:210,914,576...210,918,193
Ensembl chr 1:210,914,567...210,918,193
|
|
| G
|
Ppp1cb
|
protein phosphatase 1 catalytic subunit beta
|
decreases expression increases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of PPP1CB mRNA; Arsenic Trioxide results in decreased expression of PPP1CB protein Arsenic Trioxide results in increased expression of PPP1CB protein
|
CTD |
PMID:12852829 PMID:19364129 PMID:25419056 |
|
NCBI chr 6:29,681,099...29,712,835
Ensembl chr 6:29,681,100...29,712,924
|
|
| G
|
Ppp1r13b
|
protein phosphatase 1, regulatory subunit 13B
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of PPP1R13B mRNA
|
CTD |
PMID:21461292 |
|
NCBI chr 6:136,711,834...136,785,068
Ensembl chr 6:136,711,834...136,785,113
|
|
| G
|
Ppp1r15a
|
protein phosphatase 1, regulatory subunit 15A
|
increases expression decreases expression
|
ISO
|
Arsenic Trioxide results in increased expression of PPP1R15A mRNA Arsenic Trioxide results in decreased expression of PPP1R15A mRNA
|
CTD |
PMID:22521957 PMID:25258189 PMID:27829220 |
|
NCBI chr 1:105,136,521...105,139,596
Ensembl chr 1:105,136,525...105,139,774
|
|
| G
|
Ppp1r26
|
protein phosphatase 1, regulatory subunit 26
|
decreases response to substance
|
ISO
|
PPP1R26 protein results in decreased susceptibility to Arsenic Trioxide
|
CTD |
PMID:20707922 |
|
NCBI chr 3:32,179,686...32,188,069
Ensembl chr 3:32,177,235...32,188,264
|
|
| G
|
Ppp1r3d
|
protein phosphatase 1, regulatory subunit 3D
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of PPP1R3D mRNA
|
CTD |
PMID:22521957 |
|
NCBI chr 3:185,880,087...185,883,158
Ensembl chr 3:185,876,709...185,883,703
|
|
| G
|
Ppp1r9a
|
protein phosphatase 1, regulatory subunit 9A
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of PPP1R9A mRNA
|
CTD |
PMID:26705709 |
|
NCBI chr 4:33,936,949...34,258,927
Ensembl chr 4:33,988,827...34,258,927
|
|
| G
|
Ppp2ca
|
protein phosphatase 2 catalytic subunit alpha
|
decreases expression multiple interactions
|
ISO
|
Arsenic Trioxide results in decreased expression of PPP2CA protein Arsenic Trioxide promotes the reaction [AKT1 protein binds to PPP2CA protein]; aspartyl-glutamyl-valyl-aspartal inhibits the reaction [Arsenic Trioxide promotes the reaction [AKT1 protein binds to PPP2CA protein]]; Okadaic Acid inhibits the reaction [Arsenic Trioxide promotes the reaction [AKT1 protein binds to PPP2CA protein]]; PPP2CA protein affects the reaction [Arsenic Trioxide results in decreased expression of CXCR4 protein]
|
CTD |
PMID:21655183 PMID:25047463 |
|
NCBI chr10:36,856,534...36,878,789
|
|
| G
|
Ppp2cb
|
protein phosphatase 2 catalytic subunit beta
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of PPP2CB mRNA
|
CTD |
PMID:20458559 PMID:29633893 |
|
NCBI chr16:65,261,178...65,282,658
Ensembl chr16:65,261,181...65,282,634
|
|
| G
|
Ppp2r2c
|
protein phosphatase 2, regulatory subunit B, gamma
|
multiple interactions
|
ISO
|
[Arsenic Trioxide co-treated with apatinib] results in increased expression of PPP2R2C mRNA
|
CTD |
PMID:39223679 |
|
NCBI chr14:78,071,274...78,156,212
Ensembl chr14:78,071,274...78,156,212
|
|
| G
|
Ppp2r5a
|
protein phosphatase 2, regulatory subunit B', alpha
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of PPP2R5A mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr13:105,462,371...105,506,767
Ensembl chr13:105,462,371...105,506,767
|
|
| G
|
Ppp2r5e
|
protein phosphatase 2 regulatory subunit B', epsilon
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of PPP2R5E mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr 6:99,904,569...100,053,672
Ensembl chr 6:99,904,569...100,053,573
|
|
| G
|
Ppp3ca
|
protein phosphatase 3 catalytic subunit alpha
|
decreases expression increases expression multiple interactions
|
EXP ISO
|
Arsenic Trioxide results in decreased expression of PPP3CA mRNA Arsenic Trioxide results in increased expression of PPP3CA mRNA Arsenic Trioxide results in increased expression of PPP3CA protein Phloretin inhibits the reaction [Arsenic Trioxide results in increased expression of PPP3CA protein]
|
CTD |
PMID:17963750 PMID:29223816 PMID:34037972 |
|
NCBI chr 2:227,839,058...228,113,560
Ensembl chr 2:227,839,062...228,113,554
|
|
| G
|
Ppp3cb
|
protein phosphatase 3 catalytic subunit beta
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of PPP3CB mRNA
|
CTD |
PMID:20138156 |
|
NCBI chr15:3,809,182...3,854,204
Ensembl chr15:3,809,262...3,854,203
|
|
| G
|
Ppp4c
|
protein phosphatase 4, catalytic subunit
|
multiple interactions
|
ISO
|
[Tretinoin co-treated with Arsenic Trioxide] results in decreased expression of PPP4C protein
|
CTD |
PMID:15894607 |
|
NCBI chr 1:190,823,447...190,830,247
Ensembl chr 1:190,823,486...190,830,168
|
|
| G
|
Ppp5c
|
protein phosphatase 5, catalytic subunit
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of PPP5C mRNA
|
CTD |
PMID:35676786 |
|
NCBI chr 1:86,818,297...86,842,505
Ensembl chr 1:86,818,297...86,842,950
|
|
| G
|
Ppp6c
|
protein phosphatase 6, catalytic subunit
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of PPP6C mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 3:43,339,521...43,371,807
Ensembl chr 3:43,341,108...43,371,807
|
|
| G
|
Pprc1
|
PPARG related coactivator 1
|
multiple interactions
|
ISO
|
[Arsenic Trioxide co-treated with Ascorbic Acid] results in increased expression of PPRC1 mRNA
|
CTD |
PMID:25555879 |
|
NCBI chr 1:254,851,136...254,867,570
Ensembl chr 1:254,851,164...254,867,570
|
|
| G
|
Pram1
|
PML-RARA regulated adaptor molecule 1
|
increases expression multiple interactions
|
ISO
|
Arsenic Trioxide results in increased expression of PRAM1 mRNA; Arsenic Trioxide results in increased expression of PRAM1 protein [Arsenic Trioxide co-treated with Tretinoin] results in increased expression of PRAM1 mRNA; [monomethylarsonous acid co-treated with dimethylarsinous acid co-treated with Arsenic Trioxide] results in increased expression of PRAM1 protein; Arsenic Trioxide inhibits the reaction [PRAM1 protein results in decreased expression of MIR210 mRNA]; Arsenic Trioxide inhibits the reaction [PRAM1 protein results in decreased expression of MIR23A mRNA]; Arsenic Trioxide inhibits the reaction [PRAM1 protein results in decreased expression of RARB mRNA]; benzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketone inhibits the reaction [PRAM1 protein promotes the reaction [Arsenic Trioxide results in increased phosphorylation of JUN protein]]; PRAM1 protein promotes the reaction [Arsenic Trioxide results in increased phosphorylation of JUN protein]
|
CTD |
PMID:15637062 PMID:18941112 PMID:29774349 PMID:38179723 |
|
NCBI chr 7:15,125,813...15,142,494
|
|
| G
|
Prc1
|
protein regulator of cytokinesis 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of PRC1 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 1:143,659,312...143,681,019
Ensembl chr 1:143,659,481...143,681,012
|
|
| G
|
Prcc
|
proline rich mitotic checkpoint control factor
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to PRCC protein]
|
CTD |
PMID:26598702 |
|
NCBI chr 2:175,624,134...175,649,664
Ensembl chr 2:175,624,134...175,649,664
|
|
| G
|
Prdm8
|
PR/SET domain 8
|
multiple interactions
|
ISO
|
[Tretinoin co-treated with Arsenic Trioxide] results in decreased expression of PRDM8 mRNA
|
CTD |
PMID:15894607 |
|
NCBI chr14:11,708,477...11,728,111
Ensembl chr14:11,708,269...11,715,125
|
|
| G
|
Prdx1
|
peroxiredoxin 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of PRDX1 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 5:135,383,906...135,399,504
Ensembl chr 5:135,383,906...135,399,504
|
|
| G
|
Prdx2
|
peroxiredoxin 2
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of PRDX2 mRNA
|
CTD |
PMID:21173536 |
|
NCBI chr19:40,085,788...40,091,083
Ensembl chr19:40,084,430...40,091,006
|
|
| G
|
Prdx3
|
peroxiredoxin 3
|
decreases expression increases expression multiple interactions increases oxidation affects response to substance
|
ISO
|
Arsenic Trioxide results in decreased expression of PRDX3 mRNA; Arsenic Trioxide results in decreased expression of PRDX3 protein Arsenic Trioxide results in increased expression of PRDX3 mRNA; Arsenic Trioxide results in increased expression of PRDX3 protein Arsenic Trioxide inhibits the reaction [MYC protein binds to PRDX3 protein]; Arsenic Trioxide inhibits the reaction [MYC protein results in increased activity of PRDX3 protein]; PRDX3 protein affects the reaction [Arsenic Trioxide results in increased cleavage of and results in increased activity of PARP1 protein] Arsenic Trioxide results in increased oxidation of PRDX3 protein PRDX3 protein affects the susceptibility to Arsenic Trioxide
|
CTD |
PMID:19364129 PMID:19408305 PMID:22521957 PMID:26975474 |
|
NCBI chr 1:269,987,691...270,000,111
Ensembl chr 1:269,987,685...270,000,300
|
|
| G
|
Prdx4
|
peroxiredoxin 4
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of PRDX4 protein
|
CTD |
PMID:19364129 |
|
NCBI chr X:43,876,374...43,893,815
Ensembl chr X:43,876,417...43,893,812
|
|
| G
|
Prdx5
|
peroxiredoxin 5
|
increases expression multiple interactions
|
ISO
|
Arsenic Trioxide results in increased expression of PRDX5 mRNA [Tretinoin co-treated with Arsenic Trioxide] results in increased expression of PRDX5 mRNA; TGM2 protein affects the reaction [[Tretinoin co-treated with Arsenic Trioxide] results in increased expression of PRDX5 mRNA]
|
CTD |
PMID:25258189 PMID:37446117 |
|
NCBI chr 1:213,529,042...213,532,787
Ensembl chr 1:213,529,035...213,533,020
|
|
| G
|
Prelp
|
proline and arginine rich end leucine rich repeat protein
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of PRELP mRNA
|
CTD |
PMID:20458559 PMID:26705709 |
|
NCBI chr13:47,920,480...47,943,547
Ensembl chr13:47,922,590...47,932,324
|
|
| G
|
Prg3
|
proteoglycan 3, pro eosinophil major basic protein 2
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of PRG3 mRNA
|
CTD |
PMID:15761015 |
|
NCBI chr 3:90,478,627...90,484,760
Ensembl chr 3:90,479,154...90,484,759
|
|
| G
|
Prg4
|
proteoglycan 4
|
increases expression decreases expression
|
ISO
|
Arsenic Trioxide results in increased expression of PRG4 mRNA Arsenic Trioxide results in decreased expression of PRG4 mRNA
|
CTD |
PMID:20458559 PMID:35676786 |
|
NCBI chr13:65,037,363...65,054,764
Ensembl chr13:65,037,363...65,054,508
|
|
| G
|
Prkaa1
|
protein kinase AMP-activated catalytic subunit alpha 1
|
increases expression multiple interactions
|
ISO EXP
|
Arsenic Trioxide results in increased expression of PRKAA1 mRNA Arsenic Trioxide affects the expression of and affects the phosphorylation of PRKAA1 protein; Nicorandil affects the reaction [Arsenic Trioxide affects the expression of and affects the phosphorylation of PRKAA1 protein]
|
CTD |
PMID:30032600 PMID:32112876 PMID:38741475 |
|
NCBI chr 2:55,967,766...56,003,450
Ensembl chr 2:55,967,351...56,003,450
|
|
| G
|
Prkaca
|
protein kinase cAMP-activated catalytic subunit alpha
|
multiple interactions
|
ISO
|
PRKACA protein affects the reaction [Arsenic Trioxide results in increased expression of HMOX1 mRNA]; PRKACA protein affects the reaction [Arsenic Trioxide results in increased expression of TXN mRNA]; PRKACA protein affects the reaction [TRIM44 protein promotes the reaction [Arsenic Trioxide results in increased expression of HMOX1 mRNA]]; PRKACA protein affects the reaction [TRIM44 protein promotes the reaction [Arsenic Trioxide results in increased expression of TXN mRNA]]
|
CTD |
PMID:39152142 |
|
NCBI chr19:41,059,843...41,083,189
Ensembl chr19:41,059,843...41,086,494
|
|
| G
|
Prkar1a
|
protein kinase cAMP-dependent type I regulatory subunit alpha
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of PRKAR1A mRNA
|
CTD |
PMID:22521957 |
|
NCBI chr10:95,120,537...95,139,028
Ensembl chr10:95,120,487...95,139,025
|
|
| G
|
Prkar1b
|
protein kinase cAMP-dependent type I regulatory subunit beta
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of PRKAR1B mRNA
|
CTD |
PMID:21461292 |
|
NCBI chr12:20,606,066...20,738,766
Ensembl chr12:20,618,757...20,738,766
|
|
| G
|
Prkca
|
protein kinase C, alpha
|
decreases expression affects response to substance multiple interactions
|
ISO EXP
|
Arsenic Trioxide results in decreased expression of PRKCA mRNA PRKCA mRNA affects the susceptibility to Arsenic Trioxide Arsenic Trioxide promotes the reaction [Berberine results in decreased activity of PRKCA protein]
|
CTD |
PMID:18294404 PMID:23911876 PMID:24831965 |
|
NCBI chr10:93,388,991...93,787,617
Ensembl chr10:93,388,991...93,787,572
|
|
| G
|
Prkcb
|
protein kinase C, beta
|
multiple interactions decreases expression increases expression affects response to substance
|
ISO
|
Tretinoin promotes the reaction [Arsenic Trioxide results in increased expression of PRKCB mRNA] Arsenic Trioxide results in decreased expression of PRKCB mRNA PRKCB mRNA affects the susceptibility to Arsenic Trioxide
|
CTD |
PMID:10673743 PMID:15725085 PMID:23911876 PMID:29442453 |
|
NCBI chr 1:186,263,397...186,594,743
Ensembl chr 1:186,263,447...186,594,740
|
|
| G
|
Prkcd
|
protein kinase C, delta
|
multiple interactions increases phosphorylation
|
ISO EXP
|
[Arsenic Trioxide co-treated with Bortezomib] results in increased cleavage of and results in increased activity of PRKCD protein; Arsenic Trioxide results in increased cleavage of and results in increased activity of PRKCD protein Arsenic Trioxide results in increased phosphorylation of PRKCD protein
|
CTD |
PMID:17495969 PMID:19662097 PMID:29986281 |
|
NCBI chr16:5,775,681...5,806,122
Ensembl chr16:5,775,681...5,805,839
|
|
| G
|
Prkce
|
protein kinase C, epsilon
|
affects localization multiple interactions
|
EXP
|
Arsenic Trioxide affects the localization of PRKCE protein Arsenic Trioxide promotes the reaction [Berberine results in decreased activity of PRKCE protein]
|
CTD |
PMID:18294404 |
|
NCBI chr 6:13,718,050...14,204,931
Ensembl chr 6:13,718,050...14,204,288
|
|
| G
|
Prkch
|
protein kinase C, eta
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of PRKCH mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 6:98,027,830...98,226,486
Ensembl chr 6:98,027,646...98,226,477
|
|
| G
|
Prkcz
|
protein kinase C, zeta
|
affects response to substance
|
ISO
|
PRKCZ mRNA affects the susceptibility to Arsenic Trioxide
|
CTD |
PMID:23911876 |
|
NCBI chr 5:171,101,774...171,212,694
Ensembl chr 5:171,101,774...171,212,674
|
|
| G
|
Prkd3
|
protein kinase D3
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of PRKD3 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 6:21,784,665...21,860,600
Ensembl chr 6:21,784,673...21,860,600
|
|
| G
|
Prkn
|
parkin RBR E3 ubiquitin protein ligase
|
multiple interactions decreases expression affects localization
|
EXP ISO
|
Taurine inhibits the reaction [Arsenic Trioxide results in decreased expression of PRKN protein] Arsenic Trioxide affects the localization of PRKN protein
|
CTD |
PMID:24801902 PMID:30551535 |
|
NCBI chr 1:51,236,410...52,430,242
Ensembl chr 1:51,210,330...52,430,304
|
|
| G
|
Prlr
|
prolactin receptor
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of PRLR mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr 2:60,861,391...61,051,883
Ensembl chr 2:60,861,658...61,051,882
|
|
| G
|
Prmt1
|
protein arginine methyltransferase 1
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of PRMT1 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 1:104,595,339...104,605,552
Ensembl chr 1:104,595,335...104,604,827
|
|
| G
|
Prmt5
|
protein arginine methyltransferase 5
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to PRMT5 protein]
|
CTD |
PMID:26598702 |
|
NCBI chr15:31,938,927...31,948,318
Ensembl chr15:31,938,719...31,948,426
|
|
| G
|
Prnp
|
prion protein
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to PRNP protein]
|
CTD |
PMID:26598702 |
|
NCBI chr 3:139,639,076...139,654,420
Ensembl chr 3:139,630,144...139,658,436
|
|
| G
|
Prom1
|
prominin 1
|
decreases response to substance decreases expression increases expression multiple interactions
|
ISO
|
PROM1 protein results in decreased susceptibility to Arsenic Trioxide Arsenic Trioxide results in decreased expression of PROM1 mRNA; Arsenic Trioxide results in decreased expression of PROM1 protein Arsenic Trioxide results in increased expression of PROM1 mRNA; Arsenic Trioxide results in increased expression of PROM1 protein Arsenic Trioxide inhibits the reaction [PROM1 protein results in increased activity of NOTCH1 protein]; Arsenic Trioxide inhibits the reaction [PROM1 protein results in increased expression of HES1 mRNA]; ICG 001 affects the reaction [RORB protein affects the reaction [Arsenic Trioxide results in decreased expression of PROM1 protein]]; RORB protein affects the reaction [Arsenic Trioxide results in decreased expression of PROM1 protein]; SOX2 protein affects the reaction [Arsenic Trioxide results in increased expression of PROM1 protein]
|
CTD |
PMID:21788103 PMID:23832679 PMID:24685274 PMID:29396848 PMID:30748021 PMID:33634982 PMID:38797699 More...
|
|
NCBI chr14:71,202,303...71,307,008
Ensembl chr14:71,202,336...71,307,002
|
|
| G
|
Prom2
|
prominin 2
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of PROM2 mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr 3:135,200,944...135,215,130
Ensembl chr 3:135,200,944...135,215,077
|
|
| G
|
Prpf18
|
pre-mRNA processing factor 18
|
multiple interactions
|
ISO
|
[Tretinoin co-treated with Arsenic Trioxide] results in increased expression of PRPF18 mRNA
|
CTD |
PMID:15894607 |
|
NCBI chr17:78,539,004...78,570,483
Ensembl chr17:78,539,839...78,600,250
|
|
| G
|
Prpf40a
|
pre-mRNA processing factor 40 homolog A
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of PRPF40A mRNA
|
CTD |
PMID:35676786 |
|
NCBI chr 3:58,036,779...58,098,996
Ensembl chr 3:58,038,042...58,099,363
|
|
| G
|
Prpf8
|
pre-mRNA processing factor 8
|
multiple interactions
|
ISO
|
[Tretinoin co-treated with Arsenic Trioxide] results in increased expression of PRPF8 mRNA
|
CTD |
PMID:15894607 |
|
NCBI chr10:60,829,778...60,852,887
Ensembl chr10:60,829,778...60,852,887
|
|
| G
|
Prps1
|
phosphoribosyl pyrophosphate synthetase 1
|
increases expression decreases expression
|
ISO
|
Arsenic Trioxide results in increased expression of PRPS1 mRNA Arsenic Trioxide results in decreased expression of PRPS1 protein
|
CTD |
PMID:20458559 PMID:25419056 |
|
NCBI chr X:108,920,663...108,942,713
Ensembl chr X:108,920,651...108,942,711
|
|
| G
|
Prps2
|
phosphoribosyl pyrophosphate synthetase 2
|
multiple interactions increases expression
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to PRPS2 protein] Arsenic Trioxide results in increased expression of PRPS2 protein
|
CTD |
PMID:25419056 PMID:26598702 |
|
NCBI chr X:30,592,845...30,630,127
Ensembl chr X:30,593,019...30,630,126
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|
| G
|
Prr16
|
proline rich 16
|
decreases expression increases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of PRR16 mRNA Arsenic Trioxide results in increased expression of PRR16 mRNA
|
CTD |
PMID:15761015 PMID:26705709 |
|
NCBI chr18:46,622,816...46,963,251
Ensembl chr18:46,623,058...46,830,385
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|
| G
|
Prr3
|
proline rich 3
|
increases response to substance
|
ISO
|
PRR3 protein results in increased susceptibility to Arsenic Trioxide
|
CTD |
PMID:20707922 |
|
NCBI chr20:2,797,677...2,804,674
Ensembl chr20:2,797,105...2,798,617
|
|
| G
|
Prr5
|
proline rich 5
|
increases expression decreases expression
|
ISO
|
Arsenic Trioxide results in increased expression of PRR5 mRNA Arsenic Trioxide results in decreased expression of PRR5-ARHGAP8 mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr 7:117,675,308...117,717,833
Ensembl chr 7:117,675,383...117,717,831
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|
| G
|
Prrc1
|
proline-rich coiled-coil 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of PRRC1 mRNA
|
CTD |
PMID:22521957 |
|
NCBI chr18:53,010,606...53,047,601
Ensembl chr18:53,010,600...53,045,015
|
|
| G
|
Prrc2c
|
proline-rich coiled-coil 2C
|
increases response to substance decreases expression
|
ISO
|
PRRC2C protein results in increased susceptibility to Arsenic Trioxide Arsenic Trioxide results in decreased expression of PRRC2C mRNA
|
CTD |
PMID:20707922 PMID:39716349 |
|
NCBI chr13:77,537,226...77,606,926
Ensembl chr13:77,537,814...77,607,001
|
|
| G
|
Prrg1
|
proline rich and Gla domain 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of PRRG1 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr X:46,381,329...46,493,677
Ensembl chr X:46,383,967...46,493,700
|
|
| G
|
Prss1
|
serine protease 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of PRSS1 mRNA
|
CTD |
PMID:15761015 |
|
NCBI chr 4:71,331,249...71,334,452
Ensembl chr 4:71,331,246...71,334,452
|
|
| G
|
Prss16
|
serine protease 16
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of PRSS16 mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr17:47,210,071...47,225,377
Ensembl chr17:47,210,081...47,217,658
|
|
| G
|
Prss35
|
serine protease 35
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of PRSS35 mRNA
|
CTD |
PMID:35676786 |
|
NCBI chr 8:96,594,460...96,610,992
Ensembl chr 8:96,590,571...96,613,024
|
|
| G
|
Prtn3
|
proteinase 3
|
multiple interactions
|
ISO
|
Arsenic Trioxide promotes the reaction [Tretinoin results in decreased expression of PRTN3 mRNA]
|
CTD |
PMID:26892147 |
|
NCBI chr 7:10,472,750...10,482,037
Ensembl chr 7:10,472,755...10,482,474
|
|
| G
|
Prxl2b
|
peroxiredoxin like 2B
|
decreases expression increases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of PRXL2B mRNA Arsenic Trioxide results in increased expression of PRXL2B mRNA
|
CTD |
PMID:24356939 PMID:39716349 |
|
NCBI chr 5:170,744,953...170,747,556
Ensembl chr 5:170,744,953...170,747,556
|
|
| G
|
Psat1
|
phosphoserine aminotransferase 1
|
decreases expression increases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of PSAT1 mRNA Arsenic Trioxide results in increased expression of PSAT1 mRNA
|
CTD |
PMID:19128835 PMID:34108876 |
|
NCBI chr 1:222,623,553...222,646,187
Ensembl chr 1:222,623,556...222,655,693
|
|
| G
|
Psd3
|
pleckstrin and Sec7 domain containing 3
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of PSD3 mRNA
|
CTD |
PMID:19128835 |
|
NCBI chr16:26,238,595...26,802,535
Ensembl chr16:26,340,028...26,802,535
|
|
| G
|
Psma1
|
proteasome 20S subunit alpha 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of PSMA1 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 1:177,876,838...177,887,857
Ensembl chr 1:177,875,353...177,887,949
|
|
| G
|
Psma5
|
proteasome 20S subunit alpha 5
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of PSMA5 protein
|
CTD |
PMID:19364129 |
|
NCBI chr 2:198,584,502...198,607,867
Ensembl chr 2:198,584,505...198,607,867
|
|
| G
|
Psma6
|
proteasome 20S subunit alpha 6
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of PSMA6 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 6:78,500,676...78,531,693
Ensembl chr 6:78,500,736...78,531,717
|
|
| G
|
Psma7
|
proteasome 20S subunit alpha 7
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of PSMA7 mRNA
|
CTD |
PMID:29633893 PMID:39716349 |
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NCBI chr 3:187,514,901...187,521,289
Ensembl chr 3:187,513,441...187,521,253
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Psmb1
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proteasome 20S subunit beta 1
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increases expression
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ISO
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Arsenic Trioxide results in increased expression of PSMB1 mRNA; Arsenic Trioxide results in increased expression of PSMB1 protein
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CTD |
PMID:19549367 PMID:29633893 |
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NCBI chr 1:65,115,770...65,136,516
Ensembl chr 1:65,114,724...65,136,640
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| G
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Psmb3
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proteasome 20S subunit beta 3
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increases expression
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ISO
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Arsenic Trioxide results in increased expression of PSMB3 mRNA
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CTD |
PMID:25258189 PMID:29633893 |
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NCBI chr10:83,193,787...83,200,883
Ensembl chr10:83,193,787...83,200,883
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| G
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Psmb4
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proteasome 20S subunit beta 4
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increases expression
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ISO
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Arsenic Trioxide results in increased expression of PSMB4 mRNA
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CTD |
PMID:20458559 PMID:29633893 |
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NCBI chr 2:185,131,787...185,134,561
Ensembl chr 2:185,131,786...185,135,287
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| G
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Psmb6
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proteasome 20S subunit beta 6
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multiple interactions increases expression
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ISO
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Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to PSMB6 protein] Arsenic Trioxide results in increased expression of PSMB6 mRNA
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CTD |
PMID:12852829 PMID:26598702 PMID:29633893 |
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NCBI chr10:55,737,852...55,740,218
Ensembl chr10:55,737,888...55,740,218
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| G
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Psmb8
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proteasome 20S subunit beta 8
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decreases expression multiple interactions
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ISO
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Arsenic Trioxide results in decreased expression of PSMB8 mRNA; Arsenic Trioxide results in decreased expression of PSMB8 protein [Tretinoin co-treated with Arsenic Trioxide] results in increased expression of PSMB8 mRNA
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CTD |
PMID:15725085 PMID:15894607 PMID:19364129 PMID:27829220 |
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NCBI chr20:4,654,068...4,657,049
Ensembl chr20:4,654,068...4,657,031
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| G
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Psmb9
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proteasome 20S subunit beta 9
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decreases expression
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ISO
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Arsenic Trioxide results in decreased expression of PSMB9 mRNA
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CTD |
PMID:39716349 |
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NCBI chr20:4,668,952...4,674,421
Ensembl chr20:4,668,739...4,674,421
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| G
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Psmc2
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proteasome 26S subunit, ATPase 2
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multiple interactions decreases expression
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ISO
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[Tretinoin co-treated with Arsenic Trioxide] results in increased expression of PSMC2 mRNA Arsenic Trioxide results in decreased expression of PSMC2 protein
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CTD |
PMID:15894607 PMID:19364129 |
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NCBI chr 4:14,148,080...14,162,390
Ensembl chr 4:14,148,090...14,162,390
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| G
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Psmc3
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proteasome 26S subunit, ATPase 3
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multiple interactions increases expression
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ISO
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Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to PSMC3 protein] Arsenic Trioxide results in increased expression of PSMC3 mRNA
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CTD |
PMID:26598702 PMID:29633893 |
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NCBI chr 3:97,487,643...97,493,025
Ensembl chr 3:97,487,632...97,499,176
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| G
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Psmc4
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proteasome 26S subunit, ATPase 4
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increases expression
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ISO
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Arsenic Trioxide results in increased expression of PSMC4 mRNA
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CTD |
PMID:29633893 |
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NCBI chr 1:92,476,690...92,485,268
Ensembl chr 1:92,476,690...92,485,060
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| G
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Psmd1
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proteasome 26S subunit, non-ATPase 1
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increases expression
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ISO
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Arsenic Trioxide results in increased expression of PSMD1 mRNA
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CTD |
PMID:20458559 PMID:29633893 |
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NCBI chr 9:94,157,971...94,233,218
Ensembl chr 9:94,157,971...94,233,218
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| G
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Psmd11
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proteasome 26S subunit, non-ATPase 11
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increases expression
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ISO
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Arsenic Trioxide results in increased expression of PSMD11 mRNA
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CTD |
PMID:15894607 PMID:25258189 PMID:29633893 |
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NCBI chr10:65,923,669...65,977,523
Ensembl chr10:65,931,279...65,976,234
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| G
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Psmd12
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proteasome 26S subunit, non-ATPase 12
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increases expression
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ISO
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Arsenic Trioxide results in increased expression of PSMD12 protein
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CTD |
PMID:25419056 |
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NCBI chr10:92,937,957...92,956,601
Ensembl chr10:92,901,133...92,988,964
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| G
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Psmd13
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proteasome 26S subunit, non-ATPase 13
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multiple interactions
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ISO
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[Tretinoin co-treated with Arsenic Trioxide] results in increased expression of PSMD13 mRNA
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CTD |
PMID:15894607 |
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NCBI chr 1:205,394,248...205,406,525
Ensembl chr 1:205,393,746...205,411,651
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| G
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Psmd3
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proteasome 26S subunit, non-ATPase 3
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multiple interactions increases expression
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ISO
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Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to PSMD3 protein] Arsenic Trioxide results in increased expression of PSMD3 mRNA
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CTD |
PMID:26598702 PMID:29633893 |
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NCBI chr10:84,139,249...84,151,879
Ensembl chr10:84,139,677...84,151,878
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| G
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Psmd7
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proteasome 26S subunit, non-ATPase 7
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increases expression multiple interactions
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ISO
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Arsenic Trioxide results in increased expression of PSMD7 mRNA Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to PSMD7 protein]
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CTD |
PMID:26598702 PMID:29633893 |
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NCBI chr19:52,404,032...52,411,316
Ensembl chr19:52,404,032...52,417,871
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| G
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Psmd8
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proteasome 26S subunit, non-ATPase 8
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increases expression
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ISO
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Arsenic Trioxide results in increased expression of PSMD8 mRNA
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CTD |
PMID:20458559 |
|
NCBI chr 1:93,601,857...93,608,689
Ensembl chr 1:93,601,853...93,608,689
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| G
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Psme2
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proteasome activator subunit 2
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increases expression
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ISO
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Arsenic Trioxide results in increased expression of PSME2 protein
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CTD |
PMID:25419056 |
|
NCBI chr15:33,048,452...33,053,055
Ensembl chr15:33,048,457...33,053,102
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| G
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Psme3
|
proteasome activator subunit 3
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decreases expression
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ISO
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Arsenic Trioxide results in decreased expression of PSME3 protein
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CTD |
PMID:19364129 |
|
NCBI chr10:86,757,933...86,765,719
Ensembl chr10:86,757,899...86,818,033
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| G
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Psme4
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proteasome activator subunit 4
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increases expression
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ISO
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Arsenic Trioxide results in increased expression of PSME4 mRNA
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CTD |
PMID:22521957 PMID:26705709 |
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NCBI chr14:108,706,643...108,810,330
Ensembl chr14:108,706,643...108,810,328
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| G
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Pspc1
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paraspeckle component 1
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decreases expression
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ISO
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Arsenic Trioxide results in decreased expression of PSPC1 protein
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CTD |
PMID:19364129 |
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NCBI chr15:34,941,445...35,027,460
Ensembl chr15:34,967,477...35,026,828
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| G
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Psph
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phosphoserine phosphatase
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increases expression decreases expression
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ISO
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Arsenic Trioxide results in increased expression of PSPH mRNA Arsenic Trioxide results in decreased expression of PSPH protein
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CTD |
PMID:25258189 PMID:25419056 |
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NCBI chr12:32,527,091...32,541,182
Ensembl chr12:32,519,269...32,541,180
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| G
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Pstk
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phosphoseryl-tRNA kinase
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decreases response to substance
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ISO
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PSTK gene mutant form results in decreased susceptibility to Arsenic Trioxide
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CTD |
PMID:30815697 |
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NCBI chr 1:195,587,911...195,598,326
Ensembl chr 1:195,587,890...195,604,035
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| G
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Ptbp3
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polypyrimidine tract binding protein 3
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increases expression
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ISO
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Arsenic Trioxide results in increased expression of PTBP3 mRNA
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CTD |
PMID:17258074 |
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NCBI chr 5:79,108,376...79,194,533
Ensembl chr 5:79,108,376...79,194,508
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| G
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Ptch1
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patched 1
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decreases expression multiple interactions
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ISO EXP
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Arsenic Trioxide results in decreased expression of PTCH1 mRNA [Arsenic Trioxide co-treated with Curcumin] inhibits the reaction [Cisplatin results in increased expression of PTCH1 mRNA]; Arsenic Trioxide inhibits the reaction [Cisplatin results in increased expression of PTCH1 mRNA]
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CTD |
PMID:23861973 PMID:24685274 PMID:31612257 |
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NCBI chr17:1,548,449...1,613,461
Ensembl chr17:1,548,449...1,613,461
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| G
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Pten
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phosphatase and tensin homolog
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increases expression multiple interactions increases response to substance decreases expression
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ISO EXP
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Arsenic Trioxide results in increased expression of PTEN mRNA; Arsenic Trioxide results in increased expression of PTEN protein MAPK8 protein affects the reaction [Arsenic Trioxide results in increased expression of PTEN protein]; MIR19A inhibits the reaction [Arsenic Trioxide results in increased expression of PTEN protein]; PTEN protein promotes the reaction [Arsenic Trioxide results in decreased phosphorylation of WEE1 protein]; PTEN protein promotes the reaction [Arsenic Trioxide results in increased phosphorylation of CDK1 protein]; pyrazolanthrone inhibits the reaction [Arsenic Trioxide results in increased expression of PTEN protein]; salvin promotes the reaction [Arsenic Trioxide results in increased expression of PTEN mRNA] PTEN protein results in increased susceptibility to Arsenic Trioxide Arsenic Trioxide results in decreased expression of PTEN mRNA dapagliflozin inhibits the reaction [Arsenic Trioxide results in decreased expression of PTEN mRNA] Arsenic Trioxide results in decreased expression of PTEN protein
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CTD |
PMID:20534739 PMID:20857258 PMID:22185283 PMID:22521957 PMID:22730174 PMID:23239002 PMID:23497375 PMID:38070468 More...
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NCBI chr 1:240,043,707...240,110,330
Ensembl chr 1:240,043,707...240,110,330
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| G
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Ptgdr2
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prostaglandin D2 receptor 2
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increases expression
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ISO
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Arsenic Trioxide results in increased expression of PTGDR2 mRNA
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CTD |
PMID:15761015 |
|
NCBI chr 1:217,010,183...217,015,044
Ensembl chr 1:216,995,629...217,022,393
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| G
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Ptger2
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prostaglandin E receptor 2
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decreases expression
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ISO
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Arsenic Trioxide results in decreased expression of PTGER2 mRNA
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CTD |
PMID:20458559 |
|
NCBI chr15:20,694,765...20,708,475
Ensembl chr15:20,696,013...20,708,950
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| G
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Ptges
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prostaglandin E synthase
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multiple interactions
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ISO
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[Tetradecanoylphorbol Acetate co-treated with Arsenic Trioxide] results in increased expression of PTGES mRNA
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CTD |
PMID:18922899 |
|
NCBI chr 3:34,575,643...34,586,987
Ensembl chr 3:34,575,639...34,586,995
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| G
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Ptges3
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prostaglandin E synthase 3
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increases expression
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ISO
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Arsenic Trioxide results in increased expression of PTGES3 mRNA
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CTD |
PMID:20458559 |
|
NCBI chr 7:1,075,230...1,092,363
Ensembl chr 7:1,075,227...1,092,695
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| G
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Ptgfr
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prostaglandin F receptor
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decreases expression increases expression
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ISO
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Arsenic Trioxide results in decreased expression of PTGFR mRNA Arsenic Trioxide results in increased expression of PTGFR mRNA
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CTD |
PMID:15761015 PMID:26705709 |
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NCBI chr 2:243,390,820...243,426,647
Ensembl chr 2:243,393,350...243,425,623
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| G
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Ptgr1
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prostaglandin reductase 1
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increases expression
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ISO
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Arsenic Trioxide results in increased expression of PTGR1 mRNA
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CTD |
PMID:20458559 PMID:22521957 |
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NCBI chr 5:78,579,060...78,597,671
Ensembl chr 5:78,579,057...78,597,811
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| G
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Ptgs1
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prostaglandin-endoperoxide synthase 1
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multiple interactions decreases expression
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ISO
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Arsenic Trioxide inhibits the reaction [Tretinoin results in increased expression of PTGS1 protein] Arsenic Trioxide results in decreased expression of PTGS1 mRNA
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CTD |
PMID:18354491 PMID:26705709 PMID:38758479 |
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NCBI chr 3:39,981,419...40,002,993
Ensembl chr 3:39,981,415...40,002,990
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| G
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Ptgs2
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prostaglandin-endoperoxide synthase 2
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multiple interactions decreases expression increases expression
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ISO EXP
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[Genistein co-treated with Arsenic Trioxide] results in decreased expression of PTGS2 protein; Arsenic Trioxide promotes the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA] 3-(2,4-dichloro-5-methoxyphenyl)-2-sulfanyl-4(3H)-quinazolinone inhibits the reaction [Arsenic Trioxide results in decreased expression of PTGS2 mRNA]; 3-(2,4-dichloro-5-methoxyphenyl)-2-sulfanyl-4(3H)-quinazolinone inhibits the reaction [Arsenic Trioxide results in decreased expression of PTGS2 protein]; [Arsenic Trioxide co-treated with Dexamethasone] results in decreased expression of PTGS2 protein; [Genistein co-treated with Arsenic Trioxide] results in decreased expression of PTGS2 protein; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in decreased expression of PTGS2 mRNA]; Arsenic Trioxide results in decreased expression of and affects the localization of PTGS2 protein; CAT protein inhibits the reaction [Arsenic Trioxide results in increased expression of PTGS2 mRNA]; Celecoxib promotes the reaction [Arsenic Trioxide results in decreased expression of PTGS2 mRNA]; Celecoxib promotes the reaction [Arsenic Trioxide results in decreased expression of PTGS2 protein]; Cyclosporine inhibits the reaction [Arsenic Trioxide results in decreased expression of PTGS2 mRNA]; Cyclosporine inhibits the reaction [Arsenic Trioxide results in decreased expression of PTGS2 protein]; Melatonin inhibits the reaction [Arsenic Trioxide results in increased expression of PTGS2 mRNA]; Melatonin inhibits the reaction [Arsenic Trioxide results in increased expression of PTGS2 protein]; Potassium Iodide inhibits the reaction [Arsenic Trioxide results in increased expression of PTGS2 mRNA]; Potassium Iodide inhibits the reaction [Arsenic Trioxide results in increased expression of PTGS2 protein]; PTGS2 protein affects the reaction [Arsenic Trioxide results in increased expression of NANOG protein]; PTGS2 protein affects the reaction [Arsenic Trioxide results in increased expression of POU5F1 protein]; PTGS2 protein affects the reaction [Arsenic Trioxide results in increased expression of SOX2 protein]; SOX2 protein affects the reaction [PTGS2 protein affects the reaction [Arsenic Trioxide results in increased expression of NANOG protein]]; SOX2 protein affects the reaction [PTGS2 protein affects the reaction [Arsenic Trioxide results in increased expression of POU5F1 protein]]; SOX2 protein affects the reaction [PTGS2 protein affects the reaction [Arsenic Trioxide results in increased expression of SOX2 protein]]; zinc protoporphyrin promotes the reaction [Arsenic Trioxide results in increased expression of PTGS2] Arsenic Trioxide results in decreased expression of PTGS2; Arsenic Trioxide results in decreased expression of PTGS2 mRNA; Arsenic Trioxide results in decreased expression of PTGS2 protein Arsenic Trioxide results in increased expression of PTGS2; Arsenic Trioxide results in increased expression of PTGS2 mRNA; Arsenic Trioxide results in increased expression of PTGS2 protein Febuxostat inhibits the reaction [Arsenic Trioxide results in increased expression of PTGS2 protein]; Nicorandil inhibits the reaction [Arsenic Trioxide results in increased expression of PTGS2 protein]
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CTD |
PMID:15547942 PMID:17530438 PMID:18588940 PMID:19236750 PMID:20339114 PMID:21078540 PMID:21540248 PMID:23649692 PMID:24312908 PMID:26966376 PMID:27318970 PMID:29396848 PMID:31258454 PMID:37689273 PMID:38741475 PMID:38758479 More...
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NCBI chr13:64,714,063...64,722,320
Ensembl chr13:64,713,619...64,722,320
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| G
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Ptk2b
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protein tyrosine kinase 2 beta
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affects expression
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ISO
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Arsenic Trioxide affects the expression of PTK2B mRNA
|
CTD |
PMID:28786057 |
|
NCBI chr15:44,536,275...44,656,754
Ensembl chr15:44,531,249...44,656,806
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| G
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Ptk6
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protein tyrosine kinase 6
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decreases response to substance
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ISO
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PTK6 protein results in decreased susceptibility to Arsenic Trioxide
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CTD |
PMID:20707922 |
|
NCBI chr 3:188,684,633...188,693,224
Ensembl chr 3:188,684,633...188,693,224
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| G
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Ptma
|
prothymosin alpha
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affects expression
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ISO
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Arsenic Trioxide affects the expression of PTMA mRNA
|
CTD |
PMID:28786057 |
|
NCBI chr 9:94,624,194...94,628,276
Ensembl chr 9:94,624,196...94,628,276
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| G
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Ptpdc1
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protein tyrosine phosphatase domain containing 1
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decreases expression
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ISO
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Arsenic Trioxide results in decreased expression of PTPDC1 mRNA
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CTD |
PMID:20458559 |
|
NCBI chr17:16,235,311...16,284,160
Ensembl chr17:16,235,263...16,284,158
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| G
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Ptpn1
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protein tyrosine phosphatase, non-receptor type 1
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decreases expression multiple interactions
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ISO
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Arsenic Trioxide results in decreased expression of PTPN1 mRNA Acetylcysteine inhibits the reaction [Arsenic Trioxide promotes the reaction [Pamidronate results in decreased expression of and results in decreased activity of PTPN1 protein]]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in decreased expression of and results in decreased activity of PTPN1 protein]; Acetylcysteine inhibits the reaction [Pamidronate promotes the reaction [Arsenic Trioxide results in decreased expression of and results in decreased activity of PTPN1 protein]]; Arsenic Trioxide promotes the reaction [Pamidronate results in decreased expression of and results in decreased activity of PTPN1 protein]; Arsenic Trioxide results in decreased expression of and results in decreased activity of PTPN1 protein; Pamidronate promotes the reaction [Arsenic Trioxide results in decreased expression of and results in decreased activity of PTPN1 protein]
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CTD |
PMID:22521957 PMID:32337366 |
|
NCBI chr 3:177,056,588...177,106,424
Ensembl chr 3:177,057,659...177,106,416
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| G
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Ptpn11
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protein tyrosine phosphatase, non-receptor type 11
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decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of PTPN11 mRNA
|
CTD |
PMID:19763917 |
|
NCBI chr12:41,026,079...41,085,577
Ensembl chr12:41,043,785...41,085,577
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| G
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Ptpn13
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protein tyrosine phosphatase, non-receptor type 13
|
decreases expression
|
ISO
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Arsenic Trioxide results in decreased expression of PTPN13 mRNA
|
CTD |
PMID:34108876 |
|
NCBI chr14:6,412,841...6,587,238
Ensembl chr14:6,412,841...6,587,171
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| G
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Ptpn21
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protein tyrosine phosphatase, non-receptor type 21
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of PTPN21 mRNA
|
CTD |
PMID:25258189 |
|
NCBI chr 6:123,662,783...123,727,809
Ensembl chr 6:123,662,783...123,727,809
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| G
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Ptpn6
|
protein tyrosine phosphatase, non-receptor type 6
|
increases expression multiple interactions decreases methylation
|
ISO
|
Arsenic Trioxide results in increased expression of PTPN6 mRNA; Arsenic Trioxide results in increased expression of PTPN6 protein [Arsenic Trioxide co-treated with Decitabine] results in increased expression of PTPN6 mRNA; Arsenic Trioxide results in decreased methylation of and results in increased expression of PTPN6; pervanadate inhibits the reaction [Arsenic Trioxide results in increased expression of PTPN6 protein]; PTPN6 protein affects the reaction [Arsenic Trioxide results in decreased phosphorylation of JAK2 protein]; PTPN6 protein affects the reaction [Arsenic Trioxide results in decreased phosphorylation of STAT3 protein] Arsenic Trioxide results in decreased methylation of PTPN6 promoter
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CTD |
PMID:19619438 PMID:19950550 PMID:23815908 PMID:24762999 PMID:29409467 PMID:29633893 More...
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|
NCBI chr 4:159,212,320...159,237,069
Ensembl chr 4:159,212,320...159,237,069
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| G
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Ptprc
|
protein tyrosine phosphatase, receptor type, C
|
increases response to substance affects response to substance increases expression
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ISO
|
PTPRC protein results in increased susceptibility to Arsenic Trioxide PTPRC protein alternative form affects the susceptibility to Arsenic Trioxide Arsenic Trioxide results in increased expression of PTPRC mRNA; Arsenic Trioxide results in increased expression of PTPRC protein
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CTD |
PMID:20707922 PMID:25410152 |
|
NCBI chr13:52,147,717...52,259,810
Ensembl chr13:52,147,717...52,259,746
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| G
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Ptpre
|
protein tyrosine phosphatase, receptor type, E
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of PTPRE mRNA
|
CTD |
PMID:22521957 |
|
NCBI chr 1:199,774,195...199,924,646
Ensembl chr 1:199,774,198...199,922,242
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| G
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Ptprk
|
protein tyrosine phosphatase, receptor type, K
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of PTPRK mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr 1:18,557,091...19,056,297
Ensembl chr 1:18,558,365...19,056,107
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| G
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Ptprn2
|
protein tyrosine phosphatase, receptor type N2
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of PTPRN2 mRNA
|
CTD |
PMID:26705709 |
|
NCBI chr 6:143,582,568...144,334,573
Ensembl chr 6:143,582,547...144,336,744
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| G
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Ptpro
|
protein tyrosine phosphatase, receptor type, O
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of PTPRO mRNA
|
CTD |
PMID:26705709 |
|
NCBI chr 4:171,895,104...172,105,911
Ensembl chr 4:171,895,232...172,105,903
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| G
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Ptpru
|
protein tyrosine phosphatase, receptor type, U
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of PTPRU mRNA
|
CTD |
PMID:35676786 |
|
NCBI chr 5:149,234,624...149,308,857
Ensembl chr 5:149,234,624...149,308,833
|
|
| G
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Ptrh2
|
peptidyl-tRNA hydrolase 2
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of PTRH2 mRNA
|
CTD |
PMID:14703492 |
|
NCBI chr10:72,002,450...72,012,606
Ensembl chr10:71,985,245...72,045,352
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| G
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Pttg1
|
PTTG1 regulator of sister chromatid separation, securin
|
multiple interactions increases expression
|
ISO
|
17-(dimethylaminoethylamino)-17-demethoxygeldanamycin promotes the reaction [Arsenic Trioxide results in increased expression of PTTG1 protein]; KNK 437 promotes the reaction [Arsenic Trioxide results in increased expression of PTTG1 protein] Arsenic Trioxide results in increased expression of PTTG1 mRNA; Arsenic Trioxide results in increased expression of PTTG1 protein
|
CTD |
PMID:17547211 PMID:19371599 |
|
NCBI chr10:28,394,940...28,406,410
Ensembl chr10:28,394,814...28,406,309
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|
| G
|
Ptx3
|
pentraxin 3
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of PTX3 mRNA; Arsenic Trioxide results in increased expression of PTX3 protein
|
CTD |
PMID:27750169 |
|
NCBI chr 2:152,797,563...152,803,372
Ensembl chr 2:152,781,955...152,803,372
|
|
| G
|
Puf60
|
poly-U binding splicing factor 60
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of PUF60 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 7:109,663,490...109,674,443
Ensembl chr 7:109,663,490...109,674,724
|
|
| G
|
Purg
|
purine-rich element binding protein G
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of PURG mRNA
|
CTD |
PMID:15761015 |
|
NCBI chr16:65,435,371...65,466,437
Ensembl chr16:65,412,238...65,466,185
|
|
| G
|
Pvt1
|
Pvt1 oncogene
|
affects expression
|
ISO
|
Arsenic Trioxide affects the expression of PVT1 mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr 7:95,545,916...95,769,306
|
|
| G
|
Pwwp3a
|
PWWP domain containing 3A, DNA repair factor
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of PWWP3A mRNA
|
CTD |
PMID:22521957 |
|
NCBI chr 7:10,115,865...10,132,696
Ensembl chr 7:10,115,866...10,130,925
|
|
| G
|
Pxdn
|
peroxidasin
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of PXDN mRNA
|
CTD |
PMID:15761015 |
|
NCBI chr 6:52,308,347...52,385,943
Ensembl chr 6:52,308,364...52,385,942
|
|
| G
|
Pxk
|
PX domain containing serine/threonine kinase like
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of PXK mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr15:19,190,085...19,258,711
Ensembl chr15:19,190,085...19,258,671
|
|
| G
|
Pxmp2
|
peroxisomal membrane protein 2
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of PXMP2 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr12:52,053,951...52,064,283
Ensembl chr12:52,053,788...52,064,283
|
|
| G
|
Pycard
|
PYD and CARD domain containing
|
decreases methylation decreases expression increases expression multiple interactions
|
ISO EXP
|
Arsenic Trioxide results in decreased methylation of PYCARD promoter Arsenic Trioxide results in decreased expression of PYCARD mRNA Arsenic Trioxide results in increased expression of PYCARD mRNA; Arsenic Trioxide results in increased expression of PYCARD protein [sanguinarine co-treated with Arsenic Trioxide] results in increased expression of PYCARD mRNA Febuxostat inhibits the reaction [Arsenic Trioxide results in increased expression of PYCARD protein]
|
CTD |
PMID:19730151 PMID:24345465 PMID:24993472 PMID:37689273 |
|
NCBI chr 1:192,032,124...192,033,419
Ensembl chr 1:192,032,124...192,033,419
|
|
| G
|
Pygb
|
glycogen phosphorylase B
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of PYGB mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr 3:160,072,141...160,118,930
Ensembl chr 3:160,072,115...160,123,961
|
|
| G
|
Pygl
|
glycogen phosphorylase L
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of PYGL mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 6:94,433,558...94,476,219
Ensembl chr 6:94,426,346...94,476,269
|
|
| G
|
Qki
|
QKI, KH domain containing RNA binding
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of QKI mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 1:52,935,357...53,047,338
Ensembl chr 1:52,935,382...53,047,337
|
|
| G
|
Qsox1
|
quiescin sulfhydryl oxidase 1
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of QSOX1 mRNA
|
CTD |
PMID:19128835 |
|
NCBI chr13:70,500,060...70,537,711
Ensembl chr13:70,500,060...70,537,733
|
|
| G
|
Qtrt1
|
queuine tRNA-ribosyltransferase catalytic subunit 1
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of QTRT1 protein
|
CTD |
PMID:19364129 |
|
NCBI chr 8:28,239,993...28,249,983
Ensembl chr 8:28,242,472...28,250,398
|
|
| G
|
R3hdm2
|
R3H domain containing 2
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of R3HDM2 mRNA
|
CTD |
PMID:27829220 |
|
NCBI chr 7:65,097,685...65,225,863
Ensembl chr 7:65,097,923...65,225,862
|
|
| G
|
Rab11fip5
|
RAB11 family interacting protein 5
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of RAB11FIP5 mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr 4:119,428,766...119,466,277
Ensembl chr 4:119,428,766...119,466,213
|
|
| G
|
Rab13
|
RAB13, member RAS oncogene family
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of RAB13 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 2:177,972,535...177,977,679
Ensembl chr 2:177,972,372...177,977,684
|
|
| G
|
Rab15
|
RAB15, member RAS oncogene family
|
increases expression decreases expression
|
ISO
|
Arsenic Trioxide results in increased expression of RAB15 mRNA Arsenic Trioxide results in decreased expression of RAB15 mRNA
|
CTD |
PMID:20458559 PMID:22521957 |
|
NCBI chr 6:101,232,740...101,257,388
Ensembl chr 6:101,232,743...101,257,083
|
|
| G
|
Rab17
|
RAB17, member RAS oncogene family
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to RAB17 protein]
|
CTD |
PMID:26598702 |
|
NCBI chr 9:99,001,044...99,014,340
Ensembl chr 9:99,001,045...99,014,032
|
|
| G
|
Rab1a
|
RAB1A, member RAS oncogene family
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of RAB1A mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr14:98,623,582...98,648,766
Ensembl chr14:98,623,635...98,661,582
|
|
| G
|
Rab21
|
RAB21, member RAS oncogene family
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of RAB21 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 7:52,790,158...52,814,943
Ensembl chr 7:52,790,165...52,814,943
|
|
| G
|
Rab24
|
RAB24, member RAS oncogene family
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of RAB24 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr17:9,313,593...9,315,675
Ensembl chr17:9,313,593...9,316,575
|
|
| G
|
Rab25
|
RAB25, member RAS oncogene family
|
decreases response to substance
|
ISO
|
RAB25 protein results in decreased susceptibility to Arsenic Trioxide
|
CTD |
PMID:20707922 |
|
NCBI chr 2:176,298,124...176,304,221
Ensembl chr 2:176,298,124...176,304,221
|
|
| G
|
Rab27b
|
RAB27B, member RAS oncogene family
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of RAB27B mRNA
|
CTD |
PMID:15761015 PMID:26705709 |
|
NCBI chr18:65,870,230...66,069,597
Ensembl chr18:65,876,342...66,067,700
|
|
| G
|
Rab2a
|
RAB2A, member RAS oncogene family
|
decreases expression multiple interactions increases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of RAB2A protein [Arsenic Trioxide binds to PIN1 protein] affects the reaction [Arsenic Trioxide results in decreased expression of RAB2A protein]; Arsenic Trioxide promotes the reaction [Tretinoin results in decreased expression of RAB2A protein]; PIN1 protein affects the reaction [Arsenic Trioxide results in decreased expression of RAB2A protein]; Tretinoin promotes the reaction [Arsenic Trioxide results in decreased expression of RAB2A protein] Arsenic Trioxide results in increased expression of RAB2 mRNA
|
CTD |
PMID:20458559 PMID:30093655 |
|
NCBI chr 5:26,473,424...26,537,441
Ensembl chr 5:26,473,548...26,538,488
|
|
| G
|
Rab2b
|
RAB2B, member RAS oncogene family
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to RAB2B protein]
|
CTD |
PMID:26598702 |
|
NCBI chr15:27,441,860...27,462,479
Ensembl chr15:27,442,816...27,462,479
|
|
| G
|
Rab31
|
RAB31, member RAS oncogene family
|
multiple interactions
|
ISO
|
[Tretinoin co-treated with Arsenic Trioxide] results in increased expression of RAB31 mRNA
|
CTD |
PMID:15894607 |
|
NCBI chr 9:112,693,596...112,828,104
Ensembl chr 9:112,693,597...112,828,092
|
|
| G
|
Rab33a
|
RAB33A, member RAS oncogene family
|
increases expression multiple interactions
|
ISO
|
Arsenic Trioxide results in increased expression of RAB33A mRNA [Tretinoin co-treated with Arsenic Trioxide] results in increased expression of RAB33A mRNA
|
CTD |
PMID:15894607 PMID:20458559 |
|
NCBI chr X:132,572,133...132,584,255
Ensembl chr X:132,572,148...132,584,254
|
|
| G
|
Rab5a
|
RAB5A, member RAS oncogene family
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of RAB5A mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 9:6,720,057...6,749,456
Ensembl chr 9:6,721,122...6,749,447
|
|
| G
|
Rab5c
|
RAB5C, member RAS oncogene family
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of RAB5C mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr10:86,142,872...86,166,449
Ensembl chr10:86,142,873...86,166,449
|
|
| G
|
Rab7a
|
RAB7A, member RAS oncogene family
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of RAB7A mRNA
|
CTD |
PMID:15894607 |
|
NCBI chr 4:122,019,281...122,068,067
Ensembl chr 4:121,983,938...122,064,185
|
|
| G
|
Rabggta
|
Rab geranylgeranyltransferase subunit alpha
|
multiple interactions
|
ISO
|
[Tretinoin co-treated with Arsenic Trioxide] results in increased expression of RABGGTA mRNA
|
CTD |
PMID:15894607 |
|
NCBI chr15:33,176,268...33,183,320
Ensembl chr15:33,176,099...33,183,271
|
|
| G
|
Rabl3
|
RAB, member of RAS oncogene family-like 3
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to RABL3 protein]
|
CTD |
PMID:26598702 |
|
NCBI chr11:76,658,723...76,687,681
Ensembl chr11:76,658,723...76,687,940
|
|
| G
|
Rabl6
|
RAB, member RAS oncogene family-like 6
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of RABL6 mRNA
|
CTD |
PMID:35676786 |
|
NCBI chr 3:28,800,802...28,826,722
Ensembl chr 3:28,800,802...28,826,722
|
|
| G
|
Rac1
|
Rac family small GTPase 1
|
multiple interactions increases activity decreases expression affects localization
|
ISO
|
[ruxolitinib co-treated with Arsenic Trioxide] results in increased expression of RAC1 mRNA; [Tetradecanoylphorbol Acetate co-treated with Arsenic Trioxide] results in increased expression of RAC1 mRNA; [Tetradecanoylphorbol Acetate co-treated with Arsenic Trioxide] results in increased expression of RAC1 protein; Ascorbic Acid promotes the reaction [Arsenic Trioxide results in increased activity of RAC1 protein] Arsenic Trioxide results in decreased expression of RAC1 mRNA; Arsenic Trioxide results in decreased expression of RAC1 protein Arsenic Trioxide results in increased expression of and affects the localization of RAC1 protein; ATF4 protein promotes the reaction [Arsenic Trioxide results in increased expression of and affects the localization of RAC1 protein] Arsenic Trioxide affects the localization of RAC1 protein
|
CTD |
PMID:12239215 PMID:18424721 PMID:18922899 PMID:25419056 PMID:26238599 PMID:27638049 PMID:30012499 More...
|
|
NCBI chr12:16,150,411...16,170,864
Ensembl chr12:16,128,649...16,172,109
|
|
| G
|
Rac2
|
Rac family small GTPase 2
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of RAC2 mRNA
|
CTD |
PMID:19128835 PMID:26238599 |
|
NCBI chr 7:111,981,825...112,009,201
Ensembl chr 7:111,996,742...112,009,267
|
|
| G
|
Racgap1
|
Rac GTPase-activating protein 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of RACGAP1 mRNA
|
CTD |
PMID:17547211 |
|
NCBI chr 7:132,629,789...132,659,738
Ensembl chr 7:132,620,595...132,659,738
|
|
| G
|
Rad17
|
RAD17 checkpoint clamp loader component
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of RAD17 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 2:33,498,335...33,528,614
Ensembl chr 2:33,498,336...33,528,144
|
|
| G
|
Rad21
|
RAD21 cohesin complex component
|
affects methylation
|
ISO
|
Arsenic Trioxide affects the methylation of RAD21 promoter
|
CTD |
PMID:26046465 |
|
NCBI chr 7:85,177,715...85,204,657
Ensembl chr 7:85,177,716...85,204,657
|
|
| G
|
Rad23a
|
RAD23 homolog A, nucleotide excision repair protein
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to RAD23A protein]
|
CTD |
PMID:26598702 |
|
NCBI chr19:40,219,235...40,225,543
Ensembl chr19:40,219,636...40,225,543
|
|
| G
|
Rad23b
|
RAD23 homolog B, nucleotide excision repair protein
|
multiple interactions
|
ISO
|
[Tretinoin co-treated with Arsenic Trioxide] results in increased expression of RAD23B protein
|
CTD |
PMID:15894607 |
|
NCBI chr 5:74,885,518...74,923,621
Ensembl chr 5:74,885,516...74,962,426
|
|
| G
|
Rad50
|
RAD50 double strand break repair protein
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of RAD50 mRNA
|
CTD |
PMID:17530438 |
|
NCBI chr10:38,310,147...38,362,100
Ensembl chr10:38,310,147...38,362,100
|
|
| G
|
Rad51c
|
RAD51 paralog C
|
multiple interactions decreases expression affects expression
|
ISO
|
Metformin inhibits the reaction [Arsenic Trioxide results in decreased expression of RAD51C mRNA] Arsenic Trioxide affects the expression of RAD51C mRNA
|
CTD |
PMID:27825931 PMID:29095437 |
|
NCBI chr10:72,702,299...72,728,980
Ensembl chr10:72,702,299...72,729,143
|
|
| G
|
Rad51d
|
RAD51 paralog D
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of RAD51D mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr10:68,303,350...68,322,002
Ensembl chr10:68,238,273...68,321,902
|
|
| G
|
Rad52
|
RAD52 homolog, DNA repair protein
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of RAD52 mRNA
|
CTD |
PMID:15073043 |
|
NCBI chr 4:154,778,320...154,802,002
Ensembl chr 4:154,778,320...154,800,021
|
|
| G
|
Rad54b
|
RAD54 homolog B
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of RAD54B mRNA
|
CTD |
PMID:20458559 PMID:22521957 |
|
NCBI chr 5:29,829,465...29,901,967
Ensembl chr 5:29,855,304...29,901,964
|
|
| G
|
Rad9a
|
RAD9 checkpoint clamp component A
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of RAD9A mRNA
|
CTD |
PMID:20862710 |
|
NCBI chr 1:210,917,970...210,983,038
Ensembl chr 1:210,917,970...210,925,161
|
|
| G
|
Raf1
|
Raf-1 proto-oncogene, serine/threonine kinase
|
multiple interactions increases expression decreases expression
|
ISO EXP
|
[Arsenic Trioxide co-treated with PD 173074] results in decreased expression of RAF1 protein; [Arsenic Trioxide co-treated with PD 173074] results in decreased expression of RAF1 protein modified form; [Arsenic Trioxide results in increased susceptibility to PD 173074] which results in decreased expression of RAF1 protein; [PD 173074 results in increased susceptibility to Arsenic Trioxide] which results in decreased expression of RAF1 protein; [PD 173074 results in increased susceptibility to Arsenic Trioxide] which results in decreased expression of RAF1 protein modified form; Arsenic Trioxide promotes the reaction [PD 173074 results in decreased expression of RAF1 protein modified form]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[Arsenic Trioxide co-treated with PD 173074] results in decreased expression of RAF1 protein modified form]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[Arsenic Trioxide co-treated with PD 173074] results in decreased expression of RAF1 protein] Arsenic Trioxide results in increased expression of RAF1 mRNA Arsenic Trioxide results in decreased expression of RAF1 mRNA Phloretin inhibits the reaction [Arsenic Trioxide results in decreased expression of RAF1 mRNA]
|
CTD |
PMID:20458559 PMID:27794399 PMID:34037972 |
|
NCBI chr 4:150,352,158...150,412,813
Ensembl chr 4:150,352,160...150,412,813
|
|
| G
|
Rala
|
RAS like proto-oncogene A
|
decreases response to substance increases expression
|
ISO
|
RALA protein results in decreased susceptibility to Arsenic Trioxide Arsenic Trioxide results in increased expression of RALA mRNA
|
CTD |
PMID:20458559 PMID:22330069 |
|
NCBI chr17:51,787,682...51,840,738
Ensembl chr17:51,787,699...51,840,733
|
|
| G
|
Ralbp1
|
ralA binding protein 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of RALBP1 mRNA
|
CTD |
PMID:29633893 |
|
NCBI chr 9:112,903,289...112,940,093
Ensembl chr 9:112,903,302...112,939,659
|
|
| G
|
Ralgapa1
|
Ral GTPase activating protein catalytic subunit alpha 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of RALGAPA1 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 6:78,712,554...78,987,486
Ensembl chr 6:78,701,832...78,987,486
|
|
| G
|
Ralgdsl1
|
ral guanine nucleotide dissociation stimulator like 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of RGL1 mRNA
|
CTD |
PMID:19128835 |
|
NCBI chr13:67,184,402...67,454,019
Ensembl chr13:67,184,402...67,454,019
|
|
| G
|
Ralgps1
|
Ral GEF with PH domain and SH3 binding motif 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of RALGPS1 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 3:36,831,029...37,067,659
Ensembl chr 3:36,831,029...37,067,659
|
|
| G
|
Raly
|
RALY heterogeneous nuclear ribonucleoprotein
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of RALY protein
|
CTD |
PMID:25419056 |
|
NCBI chr 3:163,766,183...163,830,726
Ensembl chr 3:163,766,478...163,830,740
|
|
| G
|
Ramp2
|
receptor activity modifying protein 2
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of RAMP2 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr10:86,689,148...86,690,956
Ensembl chr10:86,688,703...86,691,231
|
|
| G
|
Ranbp3l
|
RAN binding protein 3-like
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of RANBP3L mRNA
|
CTD |
PMID:27829220 |
|
NCBI chr 2:59,785,070...59,840,338
Ensembl chr 2:59,785,450...59,840,334
|
|
| G
|
Ranbp9
|
RAN binding protein 9
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of RANBP9 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr17:21,426,717...21,508,964
Ensembl chr17:21,426,777...21,508,964
|
|
| G
|
Rap1b
|
RAP1B, member of RAS oncogene family
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of RAP1B mRNA
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CTD |
PMID:20458559 |
|
NCBI chr 7:55,308,922...55,342,217
Ensembl chr 7:55,308,922...55,342,217
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| G
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Rap1gap2
|
RAP1 GTPase activating protein 2
|
increases expression
|
ISO
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Arsenic Trioxide results in increased expression of RAP1GAP2 mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr10:59,753,822...59,970,946
Ensembl chr10:59,753,822...59,970,887
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| G
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Rap1gds1
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Rap1 GTPase-GDP dissociation stimulator 1
|
multiple interactions increases expression decreases expression
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to RAP1GDS1 protein] Arsenic Trioxide results in increased expression of RAP1GDS1 mRNA Arsenic Trioxide results in decreased expression of RAP1GDS1 mRNA
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CTD |
PMID:25258189 PMID:26598702 PMID:39716349 |
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NCBI chr 2:230,173,713...230,318,555
Ensembl chr 2:230,173,713...230,318,538
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| G
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Rap2c
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RAP2C, member of RAS oncogene family
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of RAP2C mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr X:135,388,881...135,401,998
Ensembl chr X:135,388,882...135,401,998
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| G
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Rapgef3
|
Rap guanine nucleotide exchange factor 3
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of RAPGEF3 mRNA
|
CTD |
PMID:35676786 |
|
NCBI chr 7:130,754,883...130,777,303
Ensembl chr 7:130,754,871...130,777,668
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| G
|
Rapgef4
|
Rap guanine nucleotide exchange factor 4
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of RAPGEF4 mRNA
|
CTD |
PMID:15761015 |
|
NCBI chr 3:77,217,024...77,509,933
Ensembl chr 3:77,217,039...77,509,978
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| G
|
Rapgef5
|
Rap guanine nucleotide exchange factor 5
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of RAPGEF5 mRNA
|
CTD |
PMID:26705709 |
|
NCBI chr 6:144,588,162...144,822,908
Ensembl chr 6:144,580,976...144,822,908
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| G
|
Raph1
|
Ras association (RalGDS/AF-6) and pleckstrin homology domains 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of RAPH1 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 9:69,397,272...69,484,174
Ensembl chr 9:69,401,517...69,484,019
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| G
|
Rara
|
retinoic acid receptor, alpha
|
multiple interactions decreases response to substance decreases expression increases degradation
|
ISO
|
Arsenic Trioxide results in increased degradation of and results in decreased expression of RARA protein 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid inhibits the reaction [Arsenic Trioxide results in increased degradation of RARA protein]; [Tretinoin co-treated with Arsenic Trioxide] results in decreased expression of RARA mRNA alternative form; [Vorinostat co-treated with Arsenic Trioxide] results in decreased expression of RARA protein mutant form; Arsenic Trioxide promotes the reaction [puerarin results in decreased expression of RARA mRNA alternative form]; Arsenic Trioxide promotes the reaction [tetraarsenic tetrasulfide results in increased degradation of [PML protein mutant form binds to RARA protein mutant form]]; Arsenic Trioxide results in increased degradation of [PML protein mutant form binds to RARA protein mutant form]; cobaltous chloride promotes the reaction [Arsenic Trioxide results in increased degradation of RARA protein mutant form]; RARA gene mutant form inhibits the reaction [Tretinoin inhibits the reaction [Arsenic Trioxide results in increased expression of HMOX1 protein]]; RARA gene mutant form inhibits the reaction [Tretinoin promotes the reaction [Arsenic Trioxide results in increased activity of CASP3 protein]]; tetraarsenic tetrasulfide promotes the reaction [Arsenic Trioxide results in increased degradation of [PML protein mutant form binds to RARA protein mutant form]] RARA gene mutant form results in decreased susceptibility to Arsenic Trioxide Arsenic Trioxide results in decreased expression of RARA mRNA mutant form; Arsenic Trioxide results in decreased expression of RARA protein; Arsenic Trioxide results in decreased expression of RARA protein mutant form Arsenic Trioxide results in increased degradation of RARA protein; Arsenic Trioxide results in increased degradation of RARA protein mutant form
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CTD |
PMID:9834237 PMID:15688020 PMID:15748426 PMID:16330433 PMID:16891316 PMID:17018029 PMID:17217047 PMID:19225113 PMID:20416161 PMID:23469683 PMID:25003661 PMID:26110921 PMID:26728337 PMID:27189198 PMID:27770503 More...
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|
NCBI chr10:84,379,780...84,424,371
Ensembl chr10:84,389,622...84,425,160
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|
| G
|
Rarb
|
retinoic acid receptor, beta
|
multiple interactions decreases expression
|
ISO
|
Arsenic Trioxide inhibits the reaction [Tretinoin results in increased expression of RARB mRNA] Arsenic Trioxide results in decreased expression of RARB mRNA Arsenic Trioxide inhibits the reaction [PRAM1 protein results in decreased expression of RARB mRNA]; Arsenic Trioxide inhibits the reaction [Tretinoin results in increased expression of RARB mRNA]; Arsenic Trioxide inhibits the reaction [Tretinoin results in increased expression of RARB protein]
|
CTD |
PMID:10673743 PMID:11133770 PMID:15688020 PMID:16184197 PMID:18941112 |
|
NCBI chr15:10,837,252...11,482,037
Ensembl chr15:11,131,358...11,482,040
|
|
| G
|
Rarg
|
retinoic acid receptor, gamma
|
multiple interactions
|
ISO
|
Arsenic Trioxide results in increased degradation of and results in decreased expression of RARG protein
|
CTD |
PMID:15688020 |
|
NCBI chr 7:135,246,427...135,268,889
Ensembl chr 7:135,246,427...135,268,889
|
|
| G
|
Rars1
|
arginyl-tRNA synthetase 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of RARS1 protein
|
CTD |
PMID:25419056 |
|
NCBI chr10:20,774,804...20,799,251
Ensembl chr10:20,774,805...20,799,251
|
|
| G
|
Rasgrf1
|
RAS protein-specific guanine nucleotide-releasing factor 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of RASGRF1 mRNA
|
CTD |
PMID:11940349 |
|
NCBI chr 8:99,324,986...99,454,099
Ensembl chr 8:99,324,749...99,454,089
|
|
| G
|
Rasl10a
|
RAS-like, family 10, member A
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of RASL10A mRNA
|
CTD |
PMID:19128835 PMID:21461292 |
|
NCBI chr14:84,169,141...84,170,519
Ensembl chr14:84,168,227...84,170,495
|
|
| G
|
Rasl11a
|
RAS-like family 11 member A
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of RASL11A mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr12:13,372,023...13,374,784
Ensembl chr12:13,372,023...13,376,451
|
|
| G
|
Rassf1
|
Ras association domain family member 1
|
decreases methylation increases expression multiple interactions
|
ISO
|
Arsenic Trioxide results in decreased methylation of RASSF1 gene; Arsenic Trioxide results in decreased methylation of RASSF1 promoter Arsenic Trioxide results in increased expression of RASSF1 mRNA; Arsenic Trioxide results in increased expression of RASSF1 protein [Arsenic Trioxide results in decreased methylation of RASSF1 promoter] which results in increased expression of RASSF1 mRNA; Arsenic Trioxide promotes the reaction [Decitabine results in increased expression of RASSF1 mRNA]; Arsenic Trioxide results in increased expression of and affects the localization of RASSF1 protein; Decitabine promotes the reaction [Arsenic Trioxide results in increased expression of RASSF1 mRNA]
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CTD |
PMID:16613325 PMID:20079060 |
|
NCBI chr 8:117,103,665...117,114,805
Ensembl chr 8:117,103,362...117,114,805
|
|
| G
|
Rassf7
|
Ras association domain family member 7
|
decreases response to substance
|
ISO
|
RASSF7 protein results in decreased susceptibility to Arsenic Trioxide
|
CTD |
PMID:20707922 |
|
NCBI chr 1:205,749,173...205,753,350
Ensembl chr 1:205,747,654...205,753,360
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|
| G
|
Rassf8
|
Ras association domain family member 8
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of RASSF8 mRNA
|
CTD |
PMID:15761015 |
|
NCBI chr 4:180,447,050...180,528,792
Ensembl chr 4:180,446,846...180,528,790
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|
| G
|
Rb1
|
RB transcriptional corepressor 1
|
decreases expression decreases phosphorylation multiple interactions
|
ISO
|
Arsenic Trioxide results in decreased expression of RB1 protein modified form Arsenic Trioxide results in decreased phosphorylation of RB1 protein [Arsenic Trioxide results in decreased activity of CDK6 protein] which results in decreased phosphorylation of RB1 protein; Arsenic Trioxide promotes the reaction [RB1 protein binds to E2F1 protein]; Arsenic Trioxide results in increased expression of and results in increased phosphorylation of RB1 protein; TP53 protein promotes the reaction [Arsenic Trioxide results in increased expression of RB1 protein]
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CTD |
PMID:10850458 PMID:12480548 PMID:20953137 PMID:25335113 PMID:34042274 |
|
NCBI chr15:54,780,858...54,911,989
Ensembl chr15:54,780,858...54,911,857
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|
| G
|
Rbbp4
|
RB binding protein 4, chromatin remodeling factor
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of RBBP4 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 5:146,940,207...146,959,501
Ensembl chr 5:146,922,611...146,959,501
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|
| G
|
Rbl1
|
RB transcriptional corepressor like 1
|
decreases methylation
|
ISO
|
Arsenic Trioxide results in decreased methylation of RBL1 promoter
|
CTD |
PMID:29159499 |
|
NCBI chr 3:166,226,187...166,289,862
Ensembl chr 3:166,226,198...166,289,376
|
|
| G
|
Rbl2
|
RB transcriptional corepressor like 2
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of RBL2 mRNA
|
CTD |
PMID:35676786 |
|
NCBI chr19:32,049,690...32,096,467
Ensembl chr19:32,049,691...32,096,411
|
|
| G
|
Rbm12
|
RNA binding motif protein 12
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to RBM12 protein]
|
CTD |
PMID:26598702 |
|
NCBI chr 3:165,069,744...165,089,994
Ensembl chr 3:165,042,878...165,090,021
|
|
| G
|
Rbm17
|
RNA binding motif protein 17
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of RBM17 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr17:71,846,941...71,863,834
Ensembl chr17:71,846,916...71,864,431
|
|
| G
|
Rbm3
|
RNA binding motif protein 3
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of RBM3 mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr X:17,020,863...17,024,341
Ensembl chr X:17,020,864...17,024,841
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|
| G
|
Rbm38
|
RNA binding motif protein 38
|
multiple interactions
|
ISO
|
[Tretinoin co-treated with Arsenic Trioxide] results in increased expression of RBM38 mRNA
|
CTD |
PMID:15894607 |
|
NCBI chr 3:182,219,898...182,232,723
Ensembl chr 3:182,219,899...182,232,714
|
|
| G
|
Rbm47
|
RNA binding motif protein 47
|
decreases response to substance
|
ISO
|
RBM47 protein results in decreased susceptibility to Arsenic Trioxide
|
CTD |
PMID:20707922 |
|
NCBI chr14:42,407,226...42,545,304
Ensembl chr14:42,466,335...42,543,163
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|
| G
|
Rbm6
|
RNA binding motif protein 6
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of RBM6 mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr 8:117,327,607...117,431,397
Ensembl chr 8:117,331,325...117,431,397
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|
| G
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Rbmx
|
RNA binding motif protein, X-linked
|
decreases expression increases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of RBMX mRNA; Arsenic Trioxide results in decreased expression of RBMX protein Arsenic Trioxide results in increased expression of RBMX mRNA
|
CTD |
PMID:12852829 PMID:20458559 PMID:25419056 |
|
NCBI chr X:140,342,544...140,352,121
Ensembl chr X:140,345,571...140,352,035
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|
| G
|
Rbp1
|
retinol binding protein 1
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to RBP1 protein]
|
CTD |
PMID:26598702 |
|
NCBI chr 8:107,904,589...107,926,109
Ensembl chr 8:107,887,417...107,983,847
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|
| G
|
Rbp2
|
retinol binding protein 2
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to RBP2 protein]
|
CTD |
PMID:26598702 |
|
NCBI chr 8:107,958,670...107,983,850
|
|
| G
|
Rbpms
|
RNA binding protein, mRNA processing factor
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of RBPMS mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr16:64,942,159...65,098,504
Ensembl chr16:64,942,530...65,098,503
|
|
| G
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Rchy1
|
ring finger and CHY zinc finger domain containing 1
|
increases expression multiple interactions
|
ISO
|
Arsenic Trioxide results in increased expression of RCHY1 mRNA RCHY1 protein promotes the reaction [Arsenic Trioxide results in increased degradation of TP63 protein mutant form]
|
CTD |
PMID:23271742 |
|
NCBI chr14:16,397,533...16,413,286
Ensembl chr14:16,397,494...16,413,451
|
|
| G
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Rcl1
|
RNA terminal phosphate cyclase-like 1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of RCL1 mRNA
|
CTD |
PMID:25258189 |
|
NCBI chr 1:236,238,078...236,282,597
Ensembl chr 1:236,238,031...236,315,894
|
|
| G
|
Rcn3
|
reticulocalbin 3
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of RCN3 mRNA
|
CTD |
PMID:25258189 |
|
NCBI chr 1:104,700,969...104,710,228
Ensembl chr 1:104,700,545...104,710,249
|
|
| G
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Reg3b
|
regenerating family member 3 beta
|
multiple interactions
|
ISO
|
[Arsenic Trioxide results in increased abundance of arsenite] which results in decreased expression of REG3B mRNA
|
CTD |
PMID:36791901 |
|
NCBI chr 4:112,419,776...112,423,014
Ensembl chr 4:112,419,776...112,423,014
|
|
| G
|
Reg3g
|
regenerating family member 3 gamma
|
multiple interactions
|
ISO
|
[Arsenic Trioxide results in increased abundance of arsenite] which results in decreased expression of REG3G mRNA
|
CTD |
PMID:36791901 |
|
NCBI chr 4:112,482,183...112,484,738
Ensembl chr 4:112,482,183...112,484,738
|
|
| G
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Rel
|
REL proto-oncogene, NF-kB subunit
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of REL protein
|
CTD |
PMID:18349030 PMID:33634982 |
|
NCBI chr14:101,891,238...101,922,324
Ensembl chr14:101,891,243...101,921,938
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|
| G
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Rela
|
RELA proto-oncogene, NF-kB subunit
|
affects localization affects expression increases expression decreases expression multiple interactions decreases activity decreases phosphorylation increases phosphorylation decreases response to substance
|
ISO EXP
|
Arsenic Trioxide affects the localization of RELA protein Arsenic Trioxide affects the expression of RELA protein Arsenic Trioxide results in increased expression of RELA protein Arsenic Trioxide results in decreased expression of RELA mRNA; Arsenic Trioxide results in decreased expression of RELA protein; Arsenic Trioxide results in decreased expression of RELA protein modified form 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of RELA protein]; 18alpha,20beta-hydroxy-11-oxo-norolean-12-en-3beta-yl-2-O-beta-D-glucopyranurosyl-alpha-D-glucopyranosiduronate magnesium tetrahydrate inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of RELA protein]; [Arsenic Trioxide co-treated with 3-(4-methylphenylsulfonyl)-2-propenenitrile co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of RELA protein; [Genistein co-treated with Arsenic Trioxide] results in decreased expression of RELA protein; Arsenic Trioxide promotes the reaction [3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [lipopolysaccharide, E coli O55-B5 affects the localization of RELA protein]]; Arsenic Trioxide results in increased expression of and results in increased phosphorylation of RELA protein; baicalin inhibits the reaction [Arsenic Trioxide results in increased expression of and results in increased phosphorylation of RELA protein]; Thioctic Acid inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of RELA protein] 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Arsenic Trioxide affects the localization of RELA protein]; [Arsenic Trioxide results in increased abundance of Arsenic] which results in increased expression of RELA protein; Apigenin inhibits the reaction [[Arsenic Trioxide results in increased abundance of Arsenic] which results in increased expression of RELA protein]; boric acid inhibits the reaction [Arsenic Trioxide results in increased expression of RELA mRNA]; boric acid inhibits the reaction [Arsenic Trioxide results in increased expression of RELA protein]; crocin inhibits the reaction [Arsenic Trioxide results in increased expression of RELA protein]; Febuxostat inhibits the reaction [Arsenic Trioxide results in increased expression of RELA protein]; Phloretin inhibits the reaction [Arsenic Trioxide affects the localization of RELA protein]; polydatin inhibits the reaction [Arsenic Trioxide results in increased expression of RELA mRNA]; trans-sodium crocetinate inhibits the reaction [Arsenic Trioxide results in increased expression of RELA protein] 3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of RELA protein]; 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of RELA protein]; 4-amino-1,8-naphthalimide inhibits the reaction [Arsenic Trioxide affects the localization of RELA protein]; [[Sulindac co-treated with Arsenic Trioxide] results in decreased phosphorylation of and results in decreased degradation of NFKBIA protein] which affects the localization of RELA protein; [Arsenic Trioxide binds to PIN1 protein] affects the reaction [Arsenic Trioxide results in decreased expression of RELA protein]; [Arsenic Trioxide co-treated with CSF2] results in decreased activity of RELA protein; [Arsenic Trioxide co-treated with Homoharringtonine] results in decreased expression of RELA protein; [Arsenic Trioxide co-treated with Plant Extracts] results in decreased expression of RELA protein; [Arsenic Trioxide co-treated with Tetradecanoylphorbol Acetate] results in decreased activity of and results in increased localization of RELA protein; [BIBR 1532 co-treated with Arsenic Trioxide] affects the expression of RELA mRNA; [Bortezomib co-treated with Arsenic Trioxide] results in decreased activity of RELA protein; Acetylcysteine inhibits the reaction [Arsenic Trioxide affects the localization of RELA protein]; allicin inhibits the reaction [Arsenic Trioxide results in increased expression of RELA protein]; Arsenic Trioxide inhibits the reaction [EZH2 protein binds to RELA protein]; Arsenic Trioxide inhibits the reaction [RELA protein binds to NFKB1 protein]; Arsenic Trioxide inhibits the reaction [TNF protein results in increased activity of RELA protein]; Arsenic Trioxide inhibits the reaction [TNF protein results in increased expression of RELA mRNA]; Arsenic Trioxide inhibits the reaction [TNF protein results in increased phosphorylation of RELA protein]; Arsenic Trioxide promotes the reaction [tetraarsenic tetrasulfide results in decreased expression of RELA mRNA]; Arsenic Trioxide promotes the reaction [tetraarsenic tetrasulfide results in decreased expression of RELA protein]; Arsenic Trioxide promotes the reaction [Tretinoin results in decreased expression of RELA protein]; Arsenic Trioxide results in decreased expression of and affects the localization of RELA protein; Arsenic Trioxide results in decreased phosphorylation of and affects the localization of RELA protein; Genistein promotes the reaction [Arsenic Trioxide results in decreased expression of RELA protein]; JAK1 protein inhibits the reaction [Arsenic Trioxide results in decreased expression of RELA protein]; MIR491 mRNA affects the reaction [Arsenic Trioxide results in decreased phosphorylation of and affects the localization of RELA protein]; PIN1 protein affects the reaction [Arsenic Trioxide results in decreased expression of RELA protein]; pyrazolanthrone inhibits the reaction [Arsenic Trioxide results in decreased activity of RELA protein]; RELA protein inhibits the reaction [Arsenic Trioxide inhibits the reaction [CXCL12 protein results in increased expression of CXCR4 protein]]; RELA protein inhibits the reaction [Arsenic Trioxide results in decreased expression of CXCR4 protein]; RELA protein inhibits the reaction [Arsenic Trioxide results in decreased expression of ITGAX protein]; STAT3 protein inhibits the reaction [Arsenic Trioxide results in decreased expression of RELA protein]; tetraarsenic tetrasulfide promotes the reaction [Arsenic Trioxide results in decreased expression of RELA mRNA]; tetraarsenic tetrasulfide promotes the reaction [Arsenic Trioxide results in decreased expression of RELA protein]; Tretinoin promotes the reaction [Arsenic Trioxide results in decreased expression of RELA protein] Arsenic Trioxide results in decreased phosphorylation of RELA protein Arsenic Trioxide results in increased expression of RELA mRNA; Arsenic Trioxide results in increased expression of RELA protein RELA protein results in decreased susceptibility to Arsenic Trioxide
|
CTD |
PMID:15073043 PMID:15314284 PMID:15547942 PMID:16105982 PMID:16174796 PMID:18349030 PMID:18575716 PMID:20435036 PMID:20471514 PMID:20534739 PMID:20889596 PMID:21078540 PMID:22384180 PMID:22488045 PMID:22949821 PMID:24680928 PMID:25047463 PMID:25196641 PMID:25436934 PMID:25972196 PMID:26110921 PMID:26160715 PMID:27561292 PMID:27664319 PMID:28115242 PMID:29130132 PMID:29274627 PMID:29396848 PMID:30093655 PMID:30333888 PMID:30368975 PMID:30612216 PMID:31258454 PMID:31307525 PMID:31734849 PMID:32305283 PMID:32645343 PMID:32920515 PMID:33173984 PMID:33634982 PMID:34037972 PMID:34303041 PMID:34333357 PMID:35317438 PMID:37689273 PMID:37730986 PMID:38237221 More...
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NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:212,333,035...212,364,817
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| G
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Relb
|
RELB proto-oncogene, NF-kB subunit
|
decreases expression multiple interactions
|
ISO
|
Arsenic Trioxide results in decreased expression of RELB mRNA; Arsenic Trioxide results in decreased expression of RELB protein Arsenic Trioxide inhibits the reaction [Homoharringtonine results in increased expression of RELB protein]
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CTD |
PMID:18349030 PMID:20458559 PMID:31307525 PMID:33634982 |
|
NCBI chr 1:88,385,717...88,413,380
Ensembl chr 1:88,385,717...88,413,420
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|
| G
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Rep15
|
RAB15 effector protein
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of REP15 mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr 4:181,682,588...181,683,661
Ensembl chr 4:181,682,588...181,683,661
|
|
| G
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Repin1
|
replication initiator 1
|
increases expression multiple interactions
|
ISO
|
Arsenic Trioxide results in increased expression of REPIN1 mRNA [Tretinoin co-treated with Arsenic Trioxide] results in increased expression of REPIN1 mRNA
|
CTD |
PMID:15894607 PMID:20458559 |
|
NCBI chr 4:78,879,910...78,885,143
Ensembl chr 4:78,880,976...78,886,413
|
|
| G
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Rere
|
arginine-glutamic acid dipeptide repeats
|
increases expression increases sumoylation
|
ISO
|
Arsenic Trioxide results in increased expression of RERE mRNA Arsenic Trioxide results in increased sumoylation of RERE protein
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CTD |
PMID:15761015 PMID:28318385 |
|
NCBI chr 5:166,048,770...166,380,559
Ensembl chr 5:166,048,844...166,380,558
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| G
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Rerg
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RAS-like, estrogen-regulated, growth-inhibitor
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decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of RERG mRNA
|
CTD |
PMID:26705709 |
|
NCBI chr 4:171,712,794...171,821,268
Ensembl chr 4:171,712,794...171,820,903
|
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| G
|
Rest
|
RE1-silencing transcription factor
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increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of REST mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr14:31,213,415...31,233,451
Ensembl chr14:31,213,415...31,248,662
|
|
| G
|
Retn
|
resistin
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increases expression multiple interactions decreases expression
|
ISO
|
Arsenic Trioxide results in increased expression of RETN mRNA [Tretinoin co-treated with Arsenic Trioxide] results in increased expression of and results in increased secretion of RETN protein; Arsenic Trioxide results in increased expression of and results in increased secretion of RETN protein; Fenofibrate inhibits the reaction [Arsenic Trioxide results in increased expression of and results in increased secretion of RETN protein] Arsenic Trioxide results in decreased expression of RETN mRNA
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CTD |
PMID:32929351 PMID:35676786 |
|
NCBI chr12:6,508,653...6,511,115
Ensembl chr12:6,508,801...6,511,116
|
|
| G
|
Rfc2
|
replication factor C subunit 2
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of RFC2 mRNA
|
CTD |
PMID:17547211 |
|
NCBI chr12:27,756,920...27,770,049
Ensembl chr12:27,756,922...27,770,025
|
|
| G
|
Rfc3
|
replication factor C subunit 3
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of RFC3 mRNA
|
CTD |
PMID:34413873 |
|
NCBI chr12:5,836,546...5,847,331
Ensembl chr12:5,836,553...5,847,340
|
|
| G
|
Rgcc
|
regulator of cell cycle
|
decreases expression increases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of RGCC mRNA Arsenic Trioxide results in increased expression of RGCC mRNA
|
CTD |
PMID:20458559 PMID:26705709 |
|
NCBI chr15:61,071,574...61,084,408
Ensembl chr15:61,071,574...61,084,408
|
|
| G
|
Rgs11
|
regulator of G-protein signaling 11
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of RGS11 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr10:15,727,279...15,735,536
Ensembl chr10:15,727,279...15,735,536
|
|
| G
|
Rgs2
|
regulator of G-protein signaling 2
|
increases expression decreases expression
|
ISO
|
Arsenic Trioxide results in increased expression of RGS2 mRNA Arsenic Trioxide results in decreased expression of RGS2 mRNA
|
CTD |
PMID:12852829 PMID:20458559 PMID:21461292 PMID:24356939 PMID:25258189 |
|
NCBI chr13:58,350,063...58,352,666
Ensembl chr13:58,349,163...58,352,697
|
|
| G
|
Rhoa
|
ras homolog family member A
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of RHOA mRNA
|
CTD |
PMID:22521957 |
|
NCBI chr 8:117,870,548...117,904,303
Ensembl chr 8:117,870,270...117,904,302
|
|
| G
|
Rhob
|
ras homolog family member B
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of RHOB mRNA
|
CTD |
PMID:26238599 |
|
NCBI chr 6:37,083,030...37,085,204
Ensembl chr 6:37,075,015...37,112,772
|
|
| G
|
Rhobtb1
|
Rho-related BTB domain containing 1
|
multiple interactions decreases expression
|
ISO
|
Metformin inhibits the reaction [Arsenic Trioxide results in decreased expression of RHOBTB1 mRNA]
|
CTD |
PMID:29095437 |
|
NCBI chr20:19,326,197...19,455,182
Ensembl chr20:19,326,212...19,402,057
|
|
| G
|
Rhoc
|
ras homolog family member C
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of RHOC mRNA
|
CTD |
PMID:26238599 |
|
NCBI chr 2:194,975,586...194,981,637
Ensembl chr 2:194,975,242...194,983,745
|
|
| G
|
Rhod
|
ras homolog family member D
|
decreases response to substance
|
ISO
|
RHOD protein results in decreased susceptibility to Arsenic Trioxide
|
CTD |
PMID:20707922 |
|
NCBI chr 1:211,138,126...211,153,953
Ensembl chr 1:211,138,126...211,152,061
|
|
| G
|
Rhof
|
ras homolog family member F, filopodia associated
|
decreases response to substance
|
ISO
|
RHOF protein results in decreased susceptibility to Arsenic Trioxide
|
CTD |
PMID:20707922 |
|
NCBI chr12:39,082,413...39,107,528
Ensembl chr12:39,091,979...39,107,528
|
|
| G
|
Rhoh
|
ras homolog family member H
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of RHOH mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr14:42,694,860...42,725,690
Ensembl chr14:42,693,413...42,749,967
|
|
| G
|
Rhoq
|
ras homolog family member Q
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of RHOQ mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 6:13,368,499...13,403,929
Ensembl chr 1:115,757,909...115,759,467
|
|
| G
|
Rhot1
|
ras homolog family member T1
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of RHOT1 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr10:65,685,687...65,760,682
Ensembl chr10:65,696,571...65,760,681
|
|
| G
|
Rimbp2
|
RIMS binding protein 2
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of RIMBP2 mRNA
|
CTD |
PMID:26705709 |
|
NCBI chr12:33,383,646...33,582,259
Ensembl chr12:33,384,007...33,593,999
|
|
| G
|
Rims1
|
regulating synaptic membrane exocytosis 1
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of RIMS1 mRNA
|
CTD |
PMID:26705709 |
|
NCBI chr 9:32,193,352...32,692,998
Ensembl chr 9:32,193,352...32,692,772
|
|
| G
|
Rims2
|
regulating synaptic membrane exocytosis 2
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of RIMS2 mRNA
|
CTD |
PMID:26705709 |
|
NCBI chr 7:72,133,004...72,644,059
Ensembl chr 7:72,133,170...72,645,499
|
|
| G
|
Rinl
|
Ras and Rab interactor-like
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of RINL mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr 1:93,204,543...93,215,851
Ensembl chr 1:93,204,789...93,215,851
|
|
| G
|
Ripk1
|
receptor interacting serine/threonine kinase 1
|
increases cleavage decreases expression increases expression
|
ISO
|
Arsenic Trioxide results in increased cleavage of RIPK1 protein Arsenic Trioxide results in decreased expression of RIPK1 mRNA Arsenic Trioxide results in increased expression of RIPK1 mRNA
|
CTD |
PMID:15314284 PMID:34108876 PMID:37230480 |
|
NCBI chr17:31,044,983...31,077,167
Ensembl chr17:31,044,994...31,077,167
|
|
| G
|
Ripor2
|
RHO family interacting cell polarization regulator 2
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of FAM65B mRNA
|
CTD |
PMID:26705709 |
|
NCBI chr17:40,751,771...40,975,611
Ensembl chr17:40,751,771...40,975,337
|
|
| G
|
Rmdn2
|
regulator of microtubule dynamics 2
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of RMDN2 mRNA
|
CTD |
PMID:26705709 |
|
NCBI chr 6:21,101,383...21,195,221
Ensembl chr 6:21,119,396...21,193,684
|
|
| G
|
Rmi2
|
RecQ mediated genome instability 2
|
multiple interactions
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to RMI2 protein]
|
CTD |
PMID:26598702 |
|
NCBI chr10:5,336,269...5,344,202
Ensembl chr10:5,338,060...5,344,235
|
|
| G
|
Rmnd1
|
required for meiotic nuclear division 1 homolog
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of RMND1 mRNA
|
CTD |
PMID:22521957 |
|
NCBI chr 1:43,265,207...43,299,748
Ensembl chr 1:43,265,207...43,299,682
|
|
| G
|
Rnase2
|
ribonuclease A family member 2
|
multiple interactions
|
ISO
|
[Tretinoin co-treated with Arsenic Trioxide] results in decreased expression of RNASE2 mRNA
|
CTD |
PMID:15894607 |
|
NCBI chr15:26,923,125...26,923,934
Ensembl chr15:26,923,134...26,923,955
|
|
| G
|
Rnaseh2a
|
ribonuclease H2, subunit A
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of RNASEH2A mRNA
|
CTD |
PMID:17547211 |
|
NCBI chr19:40,091,206...40,100,904
Ensembl chr19:40,091,210...40,100,899
|
|
| G
|
Rnasel
|
ribonuclease L
|
increases expression multiple interactions
|
ISO
|
Arsenic Trioxide results in increased expression of RNASEL mRNA Metformin inhibits the reaction [Arsenic Trioxide results in increased expression of RNASEL mRNA]
|
CTD |
PMID:29095437 |
|
NCBI chr13:68,446,641...68,460,804
Ensembl chr13:68,446,882...68,459,557
|
|
| G
|
Rnaset2
|
ribonuclease T2
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of RNASET2 mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr 1:55,133,532...55,150,701
Ensembl chr 1:55,117,492...55,150,701
|
|
| G
|
Rnd3
|
Rho family GTPase 3
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of RND3 mRNA
|
CTD |
PMID:26238599 |
|
NCBI chr 3:55,981,142...55,998,494
Ensembl chr 3:55,980,355...55,998,536
|
|
| G
|
Rnf128
|
ring finger protein 128
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of RNF128 mRNA
|
CTD |
PMID:19128835 |
|
NCBI chr X:107,968,973...108,087,037
Ensembl chr X:107,972,348...108,087,288
|
|
| G
|
Rnf13
|
ring finger protein 13
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of RNF13 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr 2:144,076,526...144,211,520
Ensembl chr 2:144,077,916...144,211,798
|
|
| G
|
Rnf130
|
ring finger protein 130
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of RNF130 mRNA
|
CTD |
PMID:35676786 |
|
NCBI chr10:34,843,920...34,957,130
Ensembl chr10:34,843,915...34,960,408
|
|
| G
|
Rnf144a
|
ring finger protein 144A
|
multiple interactions increases expression
|
ISO
|
Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to RNF144A protein] Arsenic Trioxide results in increased expression of RNF144A mRNA
|
CTD |
PMID:15761015 PMID:26598702 |
|
NCBI chr 6:48,628,241...48,748,241
Ensembl chr 6:48,631,648...48,748,179
|
|
| G
|
Rnf157
|
ring finger protein 157
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of RNF157 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr10:102,070,842...102,138,738
Ensembl chr10:102,070,842...102,155,802
|
|
| G
|
Rnf167
|
ring finger protein 167
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of RNF167 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr10:55,859,254...55,863,546
Ensembl chr10:55,859,297...55,863,905
|
|
| G
|
Rnf182
|
ring finger protein 182
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of RNF182 mRNA
|
CTD |
PMID:35676786 |
|
NCBI chr17:21,232,084...21,287,329
Ensembl chr17:21,232,084...21,299,723
|
|
| G
|
Rnf220
|
ring finger protein 220
|
decreases expression
|
ISO
|
Arsenic Trioxide results in decreased expression of RNF220 mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr 5:135,975,739...136,198,017
Ensembl chr 5:135,975,739...136,197,858
|
|
| G
|
Rnf223
|
ring finger protein 223
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of RNF223 mRNA
|
CTD |
PMID:39716349 |
|
NCBI chr 5:172,005,566...172,008,456
Ensembl chr 5:172,005,566...172,008,458
|
|
| G
|
Rnf24
|
ring finger protein 24
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of RNF24 mRNA
|
CTD |
PMID:15761015 |
|
NCBI chr 3:138,973,492...138,987,354
Ensembl chr 3:138,973,492...139,028,177
|
|
| G
|
Rnf34
|
ring finger protein 34
|
increases expression
|
ISO
|
Arsenic Trioxide results in increased expression of RNF34 mRNA
|
CTD |
PMID:20458559 |
|
NCBI chr12:39,364,461...39,385,391
Ensembl chr12:39,355,578...39,385,340
|
|
| G
|
Rnf4
|
ring finger protein 4
|
multiple interactions affects localization
|
ISO
|
[[Arsenic Trioxide results in increased sumoylation of PML protein alternative form] promotes the reaction [PML protein alternative form binds to RNF4 protein]] which results in increased degradation of PML protein alternative form; [[Arsenic Trioxide results in increased sumoylation of PML protein] promotes the reaction [PML protein binds to RNF4 protein]] which results in increased degradation of PML protein; [Arsenic Trioxide results in increased sumoylation of PML protein alternative form] promotes the reaction [PML protein alternative form binds to RNF4 protein]; [Arsenic Trioxide results in increased sumoylation of PML protein] promotes the reaction [PML protein binds to RNF4 protein]; Arsenic Trioxide promotes the reaction [RNF4 protein binds to and results in increased degradation of PML protein modified form]; Ar |